format-version: 1.2 data-version: releases/2023-08-26 date: 25:05:2023 19:03 saved-by: pfey auto-generated-by: OBO-Edit 2.2 default-namespace: Dicty Phenotypes ontology: ddpheno property_value: http://purl.org/dc/elements/1.1/description "A structured controlled vocabulary of phenotypes of the slime-mould Dictyostelium discoideum." xsd:string property_value: http://purl.org/dc/elements/1.1/title "Dicty Phenotype Ontology (DDPHENO)" xsd:string property_value: http://purl.org/dc/terms/license http://creativecommons.org/publicdomain/zero/1.0/ property_value: owl:versionInfo "2023-08-26" xsd:string [Term] id: DDPHENO:0000001 name: aberrant spore color def: "Deviation from the normal, usual, or expected spore color." [DDB:pf] synonym: "aberrant spore pigmentation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation created_by: pfey creation_date: 2013-08-14T16:28:20Z [Term] id: DDPHENO:0000002 name: aberrant standing slug morphology def: "Deviation from the normal, usual, or expected morphology of the standing slug (finger)." [DDB:pf] synonym: "aberrant finger morphology" EXACT [] synonym: "curly fingers" BROAD [] is_a: DDPHENO:0001014 ! aberrant slug development created_by: pfey creation_date: 2013-08-15T16:54:08Z [Term] id: DDPHENO:0000003 name: increased migratory slug length def: "Increase in relative or proportionate length of the slug." [DDB:pf] synonym: "increased slug length" EXACT [] synonym: "long slug" EXACT [] xref: PMID:18366659 "DDANAT:0000008" is_a: DDPHENO:0000160 ! increased migratory slug size created_by: pfey creation_date: 2013-08-16T15:21:25Z [Term] id: DDPHENO:0000004 name: decreased migratory slug size def: "Decrease in relative or proportionate dimensions of the slug." [DDB:pf] synonym: "decreased slug size" BROAD [] xref: PMID:18366659 "DDANAT:0000008" is_a: DDPHENO:0001014 ! aberrant slug development created_by: pfey creation_date: 2013-08-27T16:36:33Z [Term] id: DDPHENO:0000005 name: aberrant autophagy def: "Deviation from the normal, usual, or expected events during autophagy, a cellular catabolic process when cells digest or remodel their parts under stress." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2013-09-23T14:27:57Z [Term] id: DDPHENO:0000006 name: increased autophagy def: "Increase in extent, amount, or degree of autophagy, a cellular catabolic process when cells digest or remodel their parts under stress." [DDB:pf] is_a: DDPHENO:0000005 ! aberrant autophagy created_by: pfey creation_date: 2013-09-23T14:29:45Z [Term] id: DDPHENO:0000007 name: decreased autophagy def: "Reduction in extent, amount, or degree of autophagy, a cellular catabolic process when cells digest or remodel their parts under stress." [DDB:pf] is_a: DDPHENO:0000005 ! aberrant autophagy created_by: pfey creation_date: 2013-09-23T14:30:03Z [Term] id: DDPHENO:0000008 name: aberrant co-transcriptional gene silencing by RNA interference machinery def: "Deviation from the normal, usual, or expected events during co-transciptional gene silencing by RNA." [DDB:pf] synonym: "aberrant small RNA-mediated co-transcriptional gene silencing" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2013-10-28T15:52:58Z [Term] id: DDPHENO:0000009 name: aberrant fruiting body morphogenesis def: "Deviation from the normal, usual, or expected morphology of the fruiting body." [DDB:pg] synonym: "aberrant sorocarp morphogenesis" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000010 name: abolished co-transcriptional gene silencing by RNA interference machinery def: "Complete inability for co-transciptional gene silencing by RNA." [DDB:pf] synonym: "abolished small RNA-mediated co-transcriptional gene silencing" EXACT [] is_a: DDPHENO:0000008 ! aberrant co-transcriptional gene silencing by RNA interference machinery created_by: pfey creation_date: 2013-10-28T15:57:20Z [Term] id: DDPHENO:0000011 name: decreased co-transcriptional gene silencing by RNA interference machinery def: "Reduction in level of modification of co-transciptional gene silencing by RNA." [DDB:pf] synonym: "decreased small RNA-mediated co-transcriptional gene silencing" EXACT [] is_a: DDPHENO:0000008 ! aberrant co-transcriptional gene silencing by RNA interference machinery created_by: pfey creation_date: 2013-10-28T15:59:10Z [Term] id: DDPHENO:0000012 name: aberrant pre-miRNA processing def: "Deviation from the normal, usual, or expected events during pre-miRNA processing." [DDB:pf] comment: GO:0031054. synonym: "aberrant miRNA processing" BROAD [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2013-10-28T18:00:23Z [Term] id: DDPHENO:0000014 name: abolished pre-miRNA processing def: "Complete inability for pre-miRNA processing." [DDB:pf] synonym: "abolished miRNA processing" BROAD [] is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing created_by: pfey creation_date: 2013-10-28T18:01:47Z [Term] id: DDPHENO:0000015 name: increased pre-miRNA processing def: "Increase in level of pre-miRNA processing." [DDB:pf] synonym: "increased miRNA processing" BROAD [] is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing created_by: pfey creation_date: 2013-10-28T18:03:08Z [Term] id: DDPHENO:0000016 name: decreased pre-miRNA processing def: "Reduction in level of pre-miRNA processing." [DDB:pf] synonym: "decreased miRNA processing" BROAD [] is_a: DDPHENO:0000012 ! aberrant pre-miRNA processing created_by: pfey creation_date: 2013-10-28T18:03:53Z [Term] id: DDPHENO:0000017 name: aberrant transitive RNA interference def: "Deviation from the normal, usual, or expected events during transitive RNA interference." [DDB:pf] comment: GO:0036453. synonym: "aberrant transitive RNAi" EXACT [] is_a: DDPHENO:0000008 ! aberrant co-transcriptional gene silencing by RNA interference machinery created_by: pfey creation_date: 2013-11-06T10:25:06Z [Term] id: DDPHENO:0000018 name: abolished transitive RNA interference def: "Complete inability for transitive RNA interference." [DDB:pf] synonym: "abolished transitive RNAi" EXACT [] is_a: DDPHENO:0000017 ! aberrant transitive RNA interference created_by: pfey creation_date: 2013-11-06T10:26:55Z [Term] id: DDPHENO:0000019 name: abolished culmination def: "Complete inability for culmination." [DDB:pg] synonym: "abolished culmination involved in sorocarp development" EXACT [] synonym: "culmination defective" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000020 name: obsolete aberrant RNA interference def: "OBSOLETE Deviation from the normal, usual, or expected events during RNA interference." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2013-11-06T10:35:04Z [Term] id: DDPHENO:0000021 name: obsolete abolished RNA interference def: "OBSOLETE Complete inability for RNA interference." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2013-11-06T10:38:10Z [Term] id: DDPHENO:0000022 name: aberrant regulation of siRNA processing def: "Deviation from the normal, usual, or expected events during production of siRNA involved in RNA interference." [DDB:pf] comment: GO:0070921. synonym: "aberrant production of siRNA involved in RNA interference" EXACT [] synonym: "aberrant production of siRNA involved in RNAi" EXACT [] is_a: DDPHENO:0000008 ! aberrant co-transcriptional gene silencing by RNA interference machinery created_by: pfey creation_date: 2013-11-06T11:17:36Z [Term] id: DDPHENO:0000024 name: abolished regulation of siRNA processing def: "Complete inability for production of siRNA involved in RNA interference." [DDB:pf] synonym: "abolished production of siRNA involved in RNA interference" EXACT [] synonym: "abolished production of siRNA involved in RNAi" EXACT [] is_a: DDPHENO:0000022 ! aberrant regulation of siRNA processing created_by: pfey creation_date: 2013-11-06T11:20:17Z [Term] id: DDPHENO:0000025 name: abolished exocytosis def: "Complete inability for exocytosis." [DDB:pf] is_a: DDPHENO:0001110 ! aberrant exocytosis created_by: pfey creation_date: 2013-12-02T17:36:22Z [Term] id: DDPHENO:0000026 name: development arrests at mound stage alt_id: DDPHENO:0000319 def: "Development cannot progress past the mound stage." [DDB:pf] synonym: "development arrests at aggregate stage" EXACT [] synonym: "development arrests at tight aggregate stage" NARROW [] synonym: "development arrests at tight mound stage" NARROW [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000027 name: abolished phagosome reneutralization def: "Complete inability for phagosome reneutralization." [DDB:pf] is_a: DDPHENO:0001488 ! aberrant phagosome maturation created_by: pfey creation_date: 2013-12-02T17:39:10Z [Term] id: DDPHENO:0000028 name: abolished stalk development def: "Complete inability for stalk development." [DDB:pg] comment: GO:0031150. synonym: "abolished sorocarp stalk development" EXACT [] synonym: "abolished stalk formation" RELATED [] is_a: DDPHENO:0001012 ! aberrant stalk development [Term] id: DDPHENO:0000029 name: increased resistance to N-Phenylthiourea def: "Increase in extent, amount, or degree of resistance to N-Phenylthiourea." [DDB:pf] is_a: DDPHENO:0000041 ! aberrant response to N-Phenylthiourea created_by: pfey creation_date: 2014-01-16T15:06:08Z [Term] id: DDPHENO:0000030 name: abolished slug development def: "Complete inability to form slugs during development." [DDB:pf] synonym: "abolished slug development involved in sorocarp development" EXACT [] synonym: "abolished slug formation" RELATED [] is_a: DDPHENO:0001014 ! aberrant slug development created_by: pfey creation_date: 2014-01-24T13:54:53Z [Term] id: DDPHENO:0000031 name: obsolete abolished rate of endocytosis def: "OBSOLETE. Complete inability for rendocytosis." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-01-27T14:30:48Z [Term] id: DDPHENO:0000032 name: increased sporulation def: "Increase in extent, amount, or degree of spore formation." [DDB:pf] synonym: "increased asexual sporulation" EXACT [] synonym: "increased number of spores" RELATED [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000033 name: aberrant secretion def: "Deviation from the normal, usual, or expected events during secretion of a substance." [DDB:pf] is_a: DDPHENO:0001047 ! aberrant transport created_by: pfey creation_date: 2014-01-27T14:34:52Z [Term] id: DDPHENO:0000034 name: aberrant contractile vacuole discharge def: "Deviation from the normal, usual, or expected events during contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000033 ! aberrant secretion is_a: DDPHENO:0001110 ! aberrant exocytosis created_by: pfey creation_date: 2014-01-27T16:14:28Z [Term] id: DDPHENO:0000035 name: abolished contractile vacuole discharge def: "Complete inability for contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2014-01-27T16:15:45Z [Term] id: DDPHENO:0000036 name: increased number of tip-organizers def: "Increase in extend, amount, or degree of the number of tips." [DDB:pf] synonym: "increased number of tips" EXACT [] synonym: "multiple tips" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis is_a: DDPHENO:0001431 ! aberrant development of tipped mound [Term] id: DDPHENO:0000037 name: decreased contractile vacuole discharge def: "Reduction in extent, amount, or degree of contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2014-01-27T16:16:48Z [Term] id: DDPHENO:0000038 name: increased contractile vacuole discharge def: "Increase in extent, amount, or degree of contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2014-01-27T16:17:55Z [Term] id: DDPHENO:0000039 name: aberrant plasma membrane organization def: "Deviation from the normal, usual, or expected events during plasma membrane organization." [DDB:pf] synonym: "aberrant plasma membrane circulation" RELATED [] synonym: "aberrant plasma membrane organization and biogenesis" EXACT [] is_a: DDPHENO:0001042 ! aberrant cellular component organization created_by: pfey creation_date: 2014-01-27T16:39:23Z [Term] id: DDPHENO:0000040 name: aberrant response to chemical def: "Deviation from the normal, usual, or expected events during the response to a chemical." [DDB:pf] synonym: "aberrant response to chemical stimulus" RELATED [] is_a: DDPHENO:0001003 ! aberrant response to stimulus created_by: pfey creation_date: 2014-03-20T12:02:35Z [Term] id: DDPHENO:0000041 name: aberrant response to N-Phenylthiourea def: "Deviation from the normal, usual, or expected events during the response to N-Phenylthiourea." [DDB:pf] is_a: DDPHENO:0000040 ! aberrant response to chemical created_by: pfey creation_date: 2014-03-20T12:09:31Z [Term] id: DDPHENO:0000042 name: aberrant membrane ruffling def: "Deviation from the normal, usual, or expected events during membrane ruffling." [DDB:pf] synonym: "aberrant ruffle assembly" EXACT [] is_a: DDPHENO:0001042 ! aberrant cellular component organization created_by: pfey creation_date: 2014-03-20T13:02:03Z [Term] id: DDPHENO:0000043 name: decreased membrane ruffling def: "Reduction in extent, amount, or degree of membrane ruffling." [DDB:pf] synonym: "decreased ruffle assembly" EXACT [] is_a: DDPHENO:0000042 ! aberrant membrane ruffling created_by: pfey creation_date: 2014-03-20T13:04:44Z [Term] id: DDPHENO:0000044 name: obsolete aberrant SDF production def: "OBSLOTETE. Deviation from the normal, usual, or expected events during SDF production." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-03-20T13:59:32Z [Term] id: DDPHENO:0000045 name: aberrant phosphatidylinositol metabolism def: "Deviation from the normal, usual, or expected events during phosphatidylinositol metabolism." [DDB:pf] synonym: "aberrant phosphatidylinositol metabolic process" EXACT [] synonym: "aberrant phosphoinositide metabolism" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2014-03-20T14:03:28Z [Term] id: DDPHENO:0000046 name: aberrant phosphatidylinositol synthesis def: "Deviation from the normal, usual, or expected events during phosphatidylinositol synthesis." [DDB:pf] synonym: "aberrant phosphatidylinositol biosynthetic process" EXACT [] is_a: DDPHENO:0000045 ! aberrant phosphatidylinositol metabolism created_by: pfey creation_date: 2014-03-20T14:07:21Z [Term] id: DDPHENO:0000047 name: decreased phosphatidylinositol synthesis def: "Reduction in extent, amount, or degree of phosphatidylinositol synthesis." [DDB:pf] synonym: "decreased phosphatidylinositol biosynthetic process" EXACT [] is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol synthesis created_by: pfey creation_date: 2014-03-20T14:09:34Z [Term] id: DDPHENO:0000048 name: increased phosphatidylinositol synthesis def: "Increase in extent, amount, or degree of phosphatidylinositol synthesis." [DDB:pf] synonym: "increased phosphatidylinositol biosynthetic process" EXACT [] is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol synthesis created_by: pfey creation_date: 2014-03-20T14:10:51Z [Term] id: DDPHENO:0000049 name: abolished phosphatidylinositol synthesis def: "Complete inability for the production of phosphatidylinositol." [DDB:pf] synonym: "abolished phosphatidylinositol biosynthetic process" EXACT [] is_a: DDPHENO:0000046 ! aberrant phosphatidylinositol synthesis created_by: pfey creation_date: 2014-03-20T14:12:10Z [Term] id: DDPHENO:0000050 name: abolished cellular hypotonic response def: "Complete inability to respond to cellular hypo-osmotic stress." [DDB:pf] synonym: "abolished cellular response to hypotonic stress" EXACT [] synonym: "abolished cellular response to hypo-osmotic stress" EXACT [] is_a: DDPHENO:0001068 ! aberrant cellular hypotonic response created_by: pfey creation_date: 2014-03-26T09:43:34Z [Term] id: DDPHENO:0000051 name: decreased cellular hypotonic response def: "Reduction in extent, amount, or degree of the cellular response to hypo-osmotic stress." [DDB:pf] synonym: "decreased cellular response to hypo-osmotic stress" EXACT [] synonym: "decreased cellular response to hypotonic stress" EXACT [] is_a: DDPHENO:0001068 ! aberrant cellular hypotonic response created_by: pfey creation_date: 2014-03-26T09:45:52Z [Term] id: DDPHENO:0000052 name: increased cellular hypotonic response def: "Increase in extent, amount, or degree of the cellular response to hypo-osmotic stress." [DDB:pf] synonym: "increased cellular response to hypo-osmotic stress" EXACT [] synonym: "increased cellular response to hypotonic stress" EXACT [] is_a: DDPHENO:0001068 ! aberrant cellular hypotonic response created_by: pfey creation_date: 2014-03-26T09:49:08Z [Term] id: DDPHENO:0000053 name: decreased contractile vacuole size def: "Decrease in relative or proportionate dimensions of the contractile vacuole." [DDB:pf] is_a: DDPHENO:0001066 ! aberrant contractile vacuole morphology created_by: pfey creation_date: 2014-03-26T09:52:55Z [Term] id: DDPHENO:0000077 name: decreased fruiting body size def: "Reduction in relative or proportionate dimensions of the fruiting body." [DDB:pf] synonym: "decreased sorocarp size" EXACT [] synonym: "small fruiting body" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis [Term] id: DDPHENO:0000090 name: aberrant endocytosis def: "Deviation from the normal, usual, or expected events during endocytosis." [DDB:pg] synonym: "endocytosis defect" RELATED [] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0000094 name: obsolete spores inviable def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000098 name: aberrant prestalk A cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk A cells." [DDB:pg] synonym: "aberrant pstA cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0000099 name: decreased chemotaxis rate def: "Reduction in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp] is_a: DDPHENO:0000148 ! decreased cell motility is_a: DDPHENO:0001122 ! aberrant chemotaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0000102 name: increased number of mounds def: "Quantitative increase in mounds." [DDB:pg] synonym: "increased number of aggregates" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000104 name: aberrant protein localization to nucleolus alt_id: DDPHENO:0000097 def: "Deviation from the normal, usual, or expected events during localization of a protein to the nucleolus." [DDB:pf] synonym: "aberrant localization to nucleolus" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2014-05-21T10:46:32Z [Term] id: DDPHENO:0000105 name: abolished protein localization to nucleolus alt_id: DDPHENO:0000100 def: "Complete inability to localize a protein to the nucleolus." [DDB:pf] synonym: "abolished localization to nucleolus" BROAD [] is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2014-05-21T10:46:58Z [Term] id: DDPHENO:0000106 name: decreased protein localization to nucleolus alt_id: DDPHENO:0000103 def: "Reduction in amount or accumulation of a protein to the nucleolus." [DDB:pf] synonym: "decreased localization to nucleolus" BROAD [] is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2014-05-21T10:47:16Z [Term] id: DDPHENO:0000107 name: increased protein localization to nucleolus alt_id: DDPHENO:0000101 def: "Increase in amount or accumulation of a protein at the nucleolus." [DDB:pf] synonym: "increased localization to nucleolus" BROAD [] is_a: DDPHENO:0000104 ! aberrant protein localization to nucleolus is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2014-05-21T10:47:28Z [Term] id: DDPHENO:0000108 name: increased glucose level def: "Increase in amount or accumulation of cytosolic glucose." [DDB:pg] synonym: "increased cytosolic glucose level" NARROW [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000109 name: increased cell-cell adhesion def: "Increase in extent, amount, or degree of cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion [Term] id: DDPHENO:0000110 name: abolished cellular localization def: "Complete inability to localize to a cellular compartment or structure." [DDB:pf] comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product. is_a: DDPHENO:0001217 ! aberrant cellular localization created_by: pfey creation_date: 2014-06-02T11:45:51Z [Term] id: DDPHENO:0000111 name: increased mound size alt_id: DDPHENO:0001018 def: "Increase in relative or proportionate dimensions of the mound." [DDB:pf] synonym: "aberrant negative regulation of aggregate size" RELATED [] synonym: "increased aggregate size" EXACT [] is_a: DDPHENO:0001017 ! aberrant mound size [Term] id: DDPHENO:0000112 name: decreased cellular localization def: "Reduction in amount or accumulation at a certain cellular location." [DDB:pf] comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product. is_a: DDPHENO:0001217 ! aberrant cellular localization created_by: pfey creation_date: 2014-06-02T11:49:54Z [Term] id: DDPHENO:0000113 name: increased cellular localization def: "Increase in amount or accumulation at a certain cellular location." [DDB:pf] comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product. is_a: DDPHENO:0001217 ! aberrant cellular localization created_by: pfey creation_date: 2014-06-02T11:50:23Z [Term] id: DDPHENO:0000115 name: aberrant substrate adhesion-dependent cell spreading def: "Deviation from the normal, usual, or expected events during substrate adhesion-dependent cell spreading." [DDB:pf] synonym: "aberrant cell spreading during cell substrate adhesion" EXACT [] synonym: "aberrant substrate adhesion dependent cell spreading" EXACT [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion created_by: pfey creation_date: 2014-08-27T11:05:50Z [Term] id: DDPHENO:0000116 name: increased cell motility def: "Increase in extent, amount, or degree of cell motility." [DD:pg] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0000117 name: abolished substrate adhesion-dependent cell spreading def: "Complete inability for substrate adhesion-dependent cell spreading." [DDB:pf] synonym: "abolished cell spreading during cell substrate adhesion" EXACT [] synonym: "abolished substrate adhesion dependent cell spreading" EXACT [] is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading created_by: pfey creation_date: 2014-08-27T11:08:28Z [Term] id: DDPHENO:0000118 name: decreased substrate adhesion-dependent cell spreading def: "Reduction in extent, amount, or degree of substrate adhesion-dependent cell spreading." [DDB:pf] synonym: "decreased cell spreading during cell substrate adhesion" EXACT [] synonym: "decreased substrate adhesion dependent cell spreading" EXACT [] synonym: "reduced cell spreading during cell substrate adhesion" EXACT [] synonym: "reduced substrate adhesion dependent cell spreading" EXACT [] synonym: "reduced substrate adhesion-dependent cell spreading" EXACT [] is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading created_by: pfey creation_date: 2014-08-27T11:10:54Z [Term] id: DDPHENO:0000119 name: increased substrate adhesion-dependent cell spreading def: "Increase in extent, amount, or degree of substrate adhesion-dependent cell spreading." [DDB:pf] synonym: "increased cell spreading during cell substrate adhesion" EXACT [] synonym: "increased substrate adhesion dependent cell spreading" EXACT [] is_a: DDPHENO:0000115 ! aberrant substrate adhesion-dependent cell spreading created_by: pfey creation_date: 2014-08-27T11:11:10Z [Term] id: DDPHENO:0000120 name: aberrant cell-cell recognition def: "Deviation from the normal, usual, or expected events during cell-cell recognition." [DDB:pf] is_a: DDPHENO:0001008 ! aberrant cellular process created_by: pfey creation_date: 2014-10-02T14:41:25Z [Term] id: DDPHENO:0000121 name: decreased glucose level def: "Reduction in extent, amount or accumulation of cytosolic glucose." [DDB:pg] synonym: "decreased cytosolic glucose level" NARROW [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000122 name: aberrant cell-cell self recognition def: "Deviation from the normal, usual, or expected events during cell-cell self recognition." [DDB:pf] synonym: "aberrant kin discrimination" RELATED [] synonym: "aberrant kin recognition" BROAD [] synonym: "aberrant self recognition" BROAD [] is_a: DDPHENO:0000120 ! aberrant cell-cell recognition created_by: pfey creation_date: 2014-10-02T14:42:58Z [Term] id: DDPHENO:0000123 name: decreased cGMP-mediated signaling alt_id: DDPHENO:0000199 def: "Reduction in extent, amount, or degree of cGMP-mediated signaling." [DDB:pf] synonym: "decreased cAMP-induced cGMP pulse" RELATED [] synonym: "decreased cyclic GMP-mediated signaling" EXACT [] is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling [Term] id: DDPHENO:0000124 name: obsolete increased cAMP-induced cAMP pulse def: "OBSOLETE. Increase in extent, amount, or degree of cAMP pulse in response to cAMP." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000125 name: abolished cell-cell self recognition def: "Complete inability to perform cell-cell self recognition." [DDB:pf] synonym: "abolished kin discrimination" RELATED [] synonym: "abolished kin recognition" BROAD [] synonym: "abolished self recognition" BROAD [] is_a: DDPHENO:0000122 ! aberrant cell-cell self recognition created_by: pfey creation_date: 2014-10-02T14:52:26Z [Term] id: DDPHENO:0000126 name: increased cGMP-mediated signaling def: "Increase in extent, amount, or degree of cGMP-mediated signaling." [DDB:pf] synonym: "increased cAMP-induced cGMP pulse" RELATED [] synonym: "increased cyclic GMP-mediated signaling" EXACT [] is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling [Term] id: DDPHENO:0000127 name: aberrant socially cooperative development def: "Deviation from the normal, usual, or expected social cooperation during aggregation." [DDB:pf] synonym: "" RELATED [] synonym: "aberrant social cooperation" BROAD [] synonym: "aberrant socially cooperative aggregation" NARROW [] is_a: DDPHENO:0000483 ! aberrant aggregation created_by: pfey creation_date: 2014-10-02T16:36:10Z [Term] id: DDPHENO:0000128 name: decreased socially cooperative development def: "Reduction in social cooperation during development." [DDB:pf] comment: Involves cheating during development; cheaters make more spores than their normal share in chimeras. synonym: "cheating during development" NARROW [] synonym: "decreased social cooperation" BROAD [] is_a: DDPHENO:0000127 ! aberrant socially cooperative development created_by: pfey creation_date: 2014-10-02T16:37:23Z [Term] id: DDPHENO:0000129 name: increased resistance to naringenin def: "Increase in extent, amount, or degree of resistance to the flavonoid naringenin." [DDB:pf] is_a: DDPHENO:0000040 ! aberrant response to chemical created_by: pfey creation_date: 2014-11-06T12:16:28Z [Term] id: DDPHENO:0000130 name: obsolete decreased cAMP-induced cAMP pulse def: "OBSOLETE. Reduction in extent, amount, or degree of cAMP pulse in response to cAMP." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000131 name: obsolete increased secretion of counting factor (CF) def: "OBSOLETE. Increase in extent, amount, or degree of secretion of counting factor (CF)." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000132 name: increased actin filament bundle assembly alt_id: DDPHENO:0000303 def: "Increase in amount or accumulation of actin filament bundle assembly." [DDB:pf] synonym: "increased basal F-actin level" RELATED [] synonym: "increased basal filamentous actin level" RELATED [] is_a: DDPHENO:0000151 ! aberrant actin filament organization [Term] id: DDPHENO:0000133 name: obsolete increased ABP120 protein level def: "OBSOLETE. Increase in extent, amount, or degree ABP120 protein level." [DDB:pg] synonym: "increased level of ABP" EXACT [] is_obsolete: true [Term] id: DDPHENO:0000134 name: increased myosin II assembly def: "Increase in extent, amount, or degree of assembly of myosin II." [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0000135 name: obsolete decreased ABP120 protein level def: "OBSOLETE. Reduction in extent, amount or accumulation of ABP120 level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000136 name: decreased myosin II assembly def: "Reduction in extent, amount, or degree of myosin II assembly." [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0000137 name: decreased actin filament bundle assembly def: "Reduction in amount or accumulation of actin filament bundle assembly." [DDB:pf] synonym: "decreased basal F-actin level" RELATED [] synonym: "decreased basal filamentous actin level" RELATED [] is_a: DDPHENO:0000151 ! aberrant actin filament organization [Term] id: DDPHENO:0000138 name: decreased cell-cell adhesion def: "Reduction in extent, amount, or degree of cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion [Term] id: DDPHENO:0000139 name: decreased sexual fusion def: "Reduction in extent, amount, or degree of gamete fusion during macrocyst formation." [DDB:pf] synonym: "decreased conjugation with cellular fusion" RELATED [] is_a: DDPHENO:0001010 ! aberrant macrocyst formation [Term] id: DDPHENO:0000140 name: decreased slime trail def: "Reduction in amount or accumulation of the slime trail, acellular material from the surface sheath left behind the migratory slug." [DDB:pf] synonym: "decreased slime trail accumulation" EXACT [] synonym: "weak slime trail" EXACT [] xref: PMID:4338436 "DDANAT:0000076" is_a: DDPHENO:0001014 ! aberrant slug development [Term] id: DDPHENO:0000141 name: decreased negative chemotaxis def: "Reduction in extent, amount, or degree of chemotaxis towards a decreasing chemical concentration." [DDB:pf] is_a: DDPHENO:0001225 ! aberrant negative chemotaxis created_by: pfey creation_date: 2014-12-17T16:11:58Z [Term] id: DDPHENO:0000142 name: wild type def: "No phenotypic difference has been reported compared to wild type." [DDB:pf] synonym: "no known phenotype" RELATED [] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0000144 name: increased negative chemotaxis def: "Increase in extent, amount, or degree of chemotaxis towards a decreasing chemical concentration." [DDB:pf] is_a: DDPHENO:0001225 ! aberrant negative chemotaxis created_by: pfey creation_date: 2014-12-17T16:14:48Z [Term] id: DDPHENO:0000145 name: obsolete decreased spore viability def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000146 name: abolished negative chemotaxis def: "Complete inability for negative chemotaxis." [DDB:pf] is_a: DDPHENO:0001225 ! aberrant negative chemotaxis created_by: pfey creation_date: 2014-12-17T16:15:30Z [Term] id: DDPHENO:0000147 name: aberrant chemorepellant activity def: "Deviation from the normal, usual, or expected chemorepellant activity." [DDB:pf] comment: GO:0045499; Chemorepellant activity is the counter part_of DDPHENO:0001225 negative chemotaxis. is_a: DDPHENO:0000773 ! aberrant signaling receptor activity created_by: pfey creation_date: 2014-12-17T16:19:14Z [Term] id: DDPHENO:0000148 name: decreased cell motility alt_id: DDPHENO:0000386 def: "Reduction in extent, amount, or degree of cell motility." [DDB:pg] synonym: "decreased random cell locomotion" RELATED [] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0000149 name: aberrant cytokinesis def: "Deviation from the normal, usual, or expected events during cytokinesis." [DDB:pg] synonym: "aberrant mitotic cytokinesis" EXACT [] is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0000150 name: abolished chemorepellant activity def: "Complete inability for chemorepellant activity." [DDB:pf] synonym: "abolished chemorepellent activity" EXACT [] is_a: DDPHENO:0000147 ! aberrant chemorepellant activity created_by: pfey creation_date: 2014-12-17T16:25:50Z [Term] id: DDPHENO:0000151 name: aberrant actin filament organization def: "Deviation from the normal, usual, or expected events during actin filament organization." [DDB:pg] synonym: "aberrant F-actin organization" EXACT [] is_a: DDPHENO:0001481 ! aberrant actin cytoskeleton organization [Term] id: DDPHENO:0000152 name: increased chemorepellant activity def: "Increase in extent, amount, or degree of chemorepellant activity." [DDB:pf] synonym: "increased chemorepellent activity" EXACT [] is_a: DDPHENO:0000147 ! aberrant chemorepellant activity created_by: pfey creation_date: 2014-12-17T16:28:25Z [Term] id: DDPHENO:0000153 name: decreased chemorepellant activity def: "Reduction in extent, amount, or degree of chemorepellant activity." [DDB:pf] synonym: "decreased chemorepellent activity" EXACT [] is_a: DDPHENO:0000147 ! aberrant chemorepellant activity created_by: pfey creation_date: 2014-12-17T16:29:56Z [Term] id: DDPHENO:0000154 name: aberrant sorocarp development alt_id: DDPHENO:0000143 alt_id: DDPHENO:0000374 alt_id: DDPHENO:0000380 def: "Deviation from the normal, usual, or expected events during sorocarp development." [DDB:pg] synonym: "merged_development hypersensitive to ammonia" NARROW [] synonym: "merged_development is resistant to Li+" NARROW [] synonym: "merged_increased sensitivity to lithium" NARROW [] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0000155 name: development arrests at tipped mound stage def: "Development cannot progress past the tipped mound stage." [DDB:pf] synonym: "development arrests at tipped aggregate stage" EXACT [] is_a: DDPHENO:0000026 ! development arrests at mound stage [Term] id: DDPHENO:0000156 name: delayed aggregation alt_id: DDPHENO:0000502 alt_id: DDPHENO:0000548 def: "Late onset or slower progression through aggregation." [DDB:pg] synonym: "delayed aggregation during fruiting body development" EXACT [] synonym: "delayed aggregation involved in sorocarp development" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000157 name: delayed development of tipped mound def: "Late onset or slower progression through development of tipped mound." [DDB:pg] synonym: "delayed sorocarp development of tipped mound" EXACT [] synonym: "delayed tip formation" RELATED [] is_a: DDPHENO:0000162 ! delayed development is_a: DDPHENO:0001431 ! aberrant development of tipped mound [Term] id: DDPHENO:0000158 name: decreased mound size alt_id: DDPHENO:0001019 def: "Reduction in relative or proportionate dimensions of the mound." [DDB:pf] synonym: "decreased aggregate size" EXACT [] synonym: "decreased positive regulation of aggregate size" RELATED [] is_a: DDPHENO:0001017 ! aberrant mound size [Term] id: DDPHENO:0000159 name: development arrests at loose mound stage alt_id: DDPHENO:0000505 alt_id: DDPHENO:0000506 alt_id: DDPHENO:0000507 def: "Development cannot progress past the loose mound stage." [DDB:pf] synonym: "development arrests at loose aggregate stage" EXACT [] synonym: "development arrests at loose aggregate stage in the presence of EGTA" NARROW [] synonym: "development arrests at loose aggregate stage in the presence of TMB-8" NARROW [] synonym: "merged_development arrests at loose aggregate stage in the presence of lithium" NARROW [] is_a: DDPHENO:0000026 ! development arrests at mound stage [Term] id: DDPHENO:0000160 name: increased migratory slug size def: "Increase in relative or proportionate dimensions of the slug." [DDB:pg] synonym: "increased slug size" EXACT [] xref: PMID:18366659 "DDANAT:0000008" is_a: DDPHENO:0001014 ! aberrant slug development [Term] id: DDPHENO:0000161 name: delayed culmination def: "Late onset or slower progression through culmination." [DDBB:pg] synonym: "delayed culmination involved in sorocarp development" EXACT [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000162 name: delayed development alt_id: DDPHENO:0000418 alt_id: DDPHENO:0000508 def: "Late onset or slower progression through development." [DDB:pg] synonym: "delayed sorocarp development" EXACT [] synonym: "merged_delayed development in the presence of gossypol" NARROW [] synonym: "merged_delayed development in the presence of lithium" NARROW [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000163 name: aberrant spore morphology def: "Deviation from the normal, usual, or expected morphology of the spore." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphogenesis is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000164 name: obsolete aberrant regulation of chemorepellant activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:35:43Z [Term] id: DDPHENO:0000165 name: increased stalk length def: "Having a relative long stalk." [DDB:pg] synonym: "long stalk" EXACT [] synonym: "stalky" RELATED [] xref: PATO:0000573 is_a: DDPHENO:0000510 ! aberrant stalk morphology [Term] id: DDPHENO:0000166 name: decreased sorus size def: "Reduction in relative or proportionate dimensions of the sorus." [DDB:pg] synonym: "small sori" RELATED [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0000167 name: precocious development def: "Early onset or faster progression through development." [DDB:pg] synonym: "precocious sorocarp development" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000168 name: development arrests at slug stage def: "Development cannot progress past the migratory slug stage during development." [DDB:pf] synonym: "development arrests at migratory slug stage" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000169 name: increased prestalk cell differentiation def: "Increase in extent, amount, or degree of prestalk cell differentiation." [DDB:pg] synonym: "increased number of prestalk cells" RELATED [] synonym: "increased pst cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation is_a: DDPHENO:0001174 ! increased cell differentiation [Term] id: DDPHENO:0000170 name: increased prespore cell differentiation def: "Increase in extent, amount, or degree of differentiation into prespore cells." [DDB:pg] synonym: "increased number of prespore cells" RELATED [] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation is_a: DDPHENO:0001174 ! increased cell differentiation [Term] id: DDPHENO:0000171 name: increased growth rate alt_id: DDPHENO:0000460 alt_id: DDPHENO:0000496 def: "Increase in extent, amount, or degree of cell proliferation." [DDB:pf] synonym: "increased asexual reproduction" EXACT [] synonym: "increased growth rate in suspension" NARROW [] synonym: "increased growth rate on bacterial plates" NARROW [] is_a: DDPHENO:0001084 ! aberrant vegetative growth [Term] id: DDPHENO:0000172 name: obsolete insensitive to ammonia def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000173 name: precocious spore germination def: "Early onset or faster progression of release from spore dormancy." [DDB:pf] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000175 name: decreased prespore cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prespore cells." [DDB:pg] synonym: "decreased number of prespore cells" RELATED [] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation is_a: DDPHENO:0001175 ! decreased cell differentiation [Term] id: DDPHENO:0000176 name: increased prestalk O cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk O cells." [DDB:pf] synonym: "increased number of prestalk O cells" RELATED [] synonym: "increased pstO cell differentiation" EXACT [] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000177 name: obsolete aberrant positive regulation of chemorepellant activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the positive regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:36:44Z [Term] id: DDPHENO:0000178 name: precocious development of tipped mound def: "Early onset or faster progression through development of tipped mound." [DDB:pg] synonym: "precocious sorocarp development of tipped mound" EXACT [] synonym: "precocious tip formation" RELATED [] is_a: DDPHENO:0000167 ! precocious development is_a: DDPHENO:0001431 ! aberrant development of tipped mound [Term] id: DDPHENO:0000181 name: abolished slug migration def: "Complete inability for slugs to migrate." [DDB:pg] synonym: "abolished migratory slug locomotion" EXACT [] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000183 name: decreased number of astral microtubules def: "Reduction in extent, amount, or degree of astral microtubules." [DDB:pf] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000184 name: decreased size of astral microtubules def: "Reduction in extent or length of astral microtubules." [DDB:pf] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0000185 name: decreased resistance to nocodazole def: "Decreased tolerance of the normal, usual, or expected events towards nocodazole." [DDB:pf] is_a: DDPHENO:0000362 ! aberrant response to nocodazole [Term] id: DDPHENO:0000187 name: aberrant cell-substrate adhesion def: "Deviation from the normal, usual, or expected events during cell-substrate adhesion." [DDB:pg] synonym: "aberrant substrate adhesion" RELATED [] synonym: "defective substrate adhesion" RELATED [] is_a: DDPHENO:0001044 ! aberrant cell adhesion [Term] id: DDPHENO:0000188 name: decreased phagocytosis def: "Reduction in extent, amount, or degree of phagocytosis." [DDB:pg] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0000190 name: obsolete aberrant negative regulation of chemorepellant activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the negative regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:38:07Z [Term] id: DDPHENO:0000191 name: decreased prestalk cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk cells." [DDB:pg] synonym: "decreased number of prestalk cells" RELATED [] synonym: "decreased number of pst cells" RELATED [] synonym: "decreased pst cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation is_a: DDPHENO:0001175 ! decreased cell differentiation [Term] id: DDPHENO:0000192 name: abolished prestalk O cell differentiation def: "Complete inability for differentiation of prestalk O cells." [DDB:pf] synonym: "abolished pstO cell differentiation" EXACT [] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000193 name: abolished DIF-1 biosynthesis def: "Complete inability for DIF biosynthesis." [DDB:pf] synonym: "abolished DIF-1 biosynthetic process" EXACT [] synonym: "abolished DIF-1 production" RELATED [] synonym: "abolished differentiation inducing factor 1 biosynthesis" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis [Term] id: DDPHENO:0000195 name: decreased stalk cell differentiation def: "Reduction in extent, amount, or degree of differentiation into stalk cells." [DDB:pg] synonym: "decreased number of stalk cells" RELATED [] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation is_a: DDPHENO:0001175 ! decreased cell differentiation [Term] id: DDPHENO:0000196 name: obsolete increased protein kinase A activity def: "OBSOLETE. Increase in extent, amount, or degree of kinase a activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000197 name: obsolete increased GTP-gamma-S-stimulated guanylyl cyclase activity def: "OBSOLETE. Increase in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000198 name: obsolete aberrant activation of adenylate cyclase activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the activation of adenylate cyclase." [DDB:pg] comment: Replaced "defective in activation of adenylate cyclase (ACA)" with "aberrant activation of adenylate cyclase (ACA)"; annotations should be changed to "decreased" or "abolished" activation of adenylate cyclase. PG 10-11-2006. is_obsolete: true [Term] id: DDPHENO:0000200 name: obsolete decreased GTP-gamma-S-stimulated guanylyl cyclase activity def: "OBSOLETE. Reduction in extent, amount, or degree of GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000201 name: obsolete decreased glycogen synthase kinase 3 activity def: "OBSOLETE. Reduction in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000203 name: increased number of microtubule organizing center def: "Quantitative increase in microtubule organizing centers." [DDB:pg] is_a: DDPHENO:0000413 ! aberrant microtubule cytoskeleton organization [Term] id: DDPHENO:0000204 name: obsolete decreased extracellular counting factor component(s) level def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular counting factor component level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000205 name: obsolete decreased extracellular CF50 level def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular CF50 level." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000206 name: precocious aggregation def: "Early onset or faster progression through aggregation." [DDB:pg] synonym: "precocious aggregation during fruiting body development" EXACT [] synonym: "precocious aggregation involved in sorocarp development" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000207 name: increased standing slug length def: "Increase in relative or proportionate length of the standing slug." [DDB:pf] synonym: "long fingers" EXACT [] xref: PMID:18366659 "DDANAT:0000007 standing slug" is_a: DDPHENO:0000002 ! aberrant standing slug morphology [Term] id: DDPHENO:0000208 name: decreased standing slug width def: "Decrease in relative or proportionate width of the standing slug." [DDB:pf] synonym: "thin fingers" EXACT [] synonym: "thin standing slug" EXACT [] xref: PMID:18366659 "DDANAT:0000007 standing slug" is_a: DDPHENO:0000002 ! aberrant standing slug morphology [Term] id: DDPHENO:0000209 name: aberrant cellular response to osmotic stress def: "Deviation from the normal, usual, or expected events during the cellular response to osmotic stress." [DDB:pf] comment: GO:0071470. is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0000210 name: delayed slug development def: "Late onset or slower progression through slug development." [DDB:pg] synonym: "delayed slug development involved in sorocarp development" EXACT [] synonym: "delayed slug formation" RELATED [] is_a: DDPHENO:0001014 ! aberrant slug development [Term] id: DDPHENO:0000211 name: aberrant cellular response to nitrogen starvation def: "Deviation from the normal, usual, or expected events during the cellular response to nitrogen starvation." [DDB:pf] is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus [Term] id: DDPHENO:0000212 name: aberrant macroautophagy def: "Deviation from the normal, usual, or expected events during macroautophagy." [DDB:pf] comment: GO:0016236. is_a: DDPHENO:0000005 ! aberrant autophagy [Term] id: DDPHENO:0000213 name: increased cell-substrate adhesion def: "Increase in extent, amount, or degree of cell-substrate adhesion." [DDB:pg] synonym: "increased substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000214 name: precocious sporulation def: "Early onset or faster progression through spore formation." [DDB:pf] synonym: "precocious asexual sporulation" EXACT [] synonym: "precocious spore differentiation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000215 name: decreased spore resistance to hydrogen peroxide def: "Decreased tolerance of the normal, usual, or expected events in spores towards hydrogen peroxide." [DDB:pf] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000216 name: aberrant spore coat morphology def: "Deviation from the normal, usual, or expected morphology of the spore coat." [DDB:pg] synonym: "aberrant spore wall morphology" EXACT [] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0000222 name: aberrant phototaxis def: "Deviation from the normal, usual, or expected events during the response to light." [DDB:pf] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0000223 name: aberrant thermotaxis def: "Deviation from the normal, usual, or expected events during the response to temperature changes." [DDB:pf] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0000225 name: decreased slug migration def: "Reduction in extent, amount, or degree of slug migration." [DDB:pg] synonym: "decreased migratory slug locomotion" EXACT [] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000226 name: increased prestalk A cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk A cells." [DDB:pg] synonym: "increased number of prestalk A cells" RELATED [] synonym: "increased pstA cell differentiation" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000169 ! increased prestalk cell differentiation [Term] id: DDPHENO:0000227 name: obsolete abolished regulation of chemorepellant activity def: "OBSOLETE Complete inability of the regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:39:18Z [Term] id: DDPHENO:0000228 name: obsolete abolished positive regulation of chemorepellant activity def: "OBSOLETE Complete inability of the positive regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:39:53Z [Term] id: DDPHENO:0000229 name: obsolete abolished negative regulation of chemorepellant activity def: "OBSOLETE Complete inability of the negative regulation of chemorepellant activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2014-12-17T16:40:31Z [Term] id: DDPHENO:0000230 name: aberrant endosome morphology def: "Deviation from the normal, usual, or expected morphology of the endosome." [DDB:pg] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000231 name: increased cell death def: "Increase in extent, amount, or degree of cell death." [DDB:pf] synonym: "decreased cell viability" RELATED [] is_a: DDPHENO:0001267 ! aberrant cell death created_by: pfey creation_date: 2014-12-19T15:32:33Z [Term] id: DDPHENO:0000232 name: decreased spore germination def: "Reduction in extent, amount, or degree of release from spore dormancy." [DDB:pf] synonym: "decreased spore viability" BROAD [] is_a: DDPHENO:0001046 ! aberrant spore germination [Term] id: DDPHENO:0000233 name: aberrant contractile vacuole organization def: "Deviation from the normal, usual, or expected organization and biogenesis of the contractile vacuole." [DDB:pf] is_a: DDPHENO:0001041 ! aberrant vacuole organization [Term] id: DDPHENO:0000234 name: aberrant mitosis def: "Deviation from the normal, usual, or expected events during mitosis." [DDB:pg] synonym: "mitotic nuclear division" EXACT [] is_a: DDPHENO:0001418 ! aberrant cell cycle [Term] id: DDPHENO:0000235 name: obsolete increased aneuploidy def: "OBSOLETE. Increase in extent, amount, or degree of aneuploidy." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000236 name: aberrant cell morphogenesis def: "Deviation from the normal, usual, or expected morphology of a cell." [DDB:pg] comment: GO:0000902. is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000237 name: decreased cell death def: "Reduction in extent, amount, or degree of cell death." [DDB:pf] synonym: "increased cell viability" RELATED [] is_a: DDPHENO:0001267 ! aberrant cell death created_by: pfey creation_date: 2014-12-19T15:35:54Z [Term] id: DDPHENO:0000238 name: obsolete aberrant DNA mediated transformation def: "OBSOLETE. Deviation from the normal, usual, or expected events during DNA-mediated transformation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-01-27T11:45:54Z [Term] id: DDPHENO:0000239 name: obsolete decreased DNA mediated transformation def: "OBSOLETE. Reduction in extent, amount or degree of DNA mediated transformation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-01-27T11:48:35Z [Term] id: DDPHENO:0000240 name: obsolete increased DNA mediated transformation def: "OBSOLETE. Increase in extent, amount, or degree of DNA mediated transformation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-01-27T11:48:59Z [Term] id: DDPHENO:0000241 name: obsolete abolished DNA mediated transformation def: "OBSOLETE. Complete inability for DNA-mediated transformation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-01-29T14:57:44Z [Term] id: DDPHENO:0000242 name: aberrant DNA repair def: "Deviation from the normal, usual, or expected events during DNA repair." [DDB:pf] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus created_by: pfey creation_date: 2015-02-12T14:58:49Z [Term] id: DDPHENO:0000243 name: aberrant single-strand break repair def: "Deviation from the normal, usual, or expected events during single-strand break DNA repair." [DDB:pf] is_a: DDPHENO:0000242 ! aberrant DNA repair created_by: pfey creation_date: 2015-02-12T14:59:35Z [Term] id: DDPHENO:0000244 name: aberrant double-strand break repair def: "Deviation from the normal, usual, or expected events during double-strand break DNA repair." [DDB:pf] synonym: "aberrant double strand break repair" EXACT [] synonym: "aberrant DSB repair" EXACT [] is_a: DDPHENO:0000242 ! aberrant DNA repair created_by: pfey creation_date: 2015-02-12T15:00:20Z [Term] id: DDPHENO:0000245 name: decreased double-strand break repair def: "Reduction in extent, amount, or degree of double strand break DNA repair." [DDB:pf] is_a: DDPHENO:0000244 ! aberrant double-strand break repair created_by: pfey creation_date: 2015-02-12T15:03:53Z [Term] id: DDPHENO:0000246 name: decreased single-strand break repair def: "Reduction in extent, amount, or degree of single-strand break repair of DNA." [DDB:pf] is_a: DDPHENO:0000243 ! aberrant single-strand break repair created_by: pfey creation_date: 2015-02-12T15:04:21Z [Term] id: DDPHENO:0000247 name: abolished double strand break repair def: "Complete inability for double strand break DNA repair." [DDB:pf] is_a: DDPHENO:0000244 ! aberrant double-strand break repair created_by: pfey creation_date: 2015-02-12T15:06:27Z [Term] id: DDPHENO:0000248 name: abolished single-strand break repair def: "Complete inability for single-strand break repair of DNA." [DDB:pf] is_a: DDPHENO:0000243 ! aberrant single-strand break repair created_by: pfey creation_date: 2015-02-12T15:06:50Z [Term] id: DDPHENO:0000249 name: increased double-strand break repair def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair." [DDB:pf] is_a: DDPHENO:0000244 ! aberrant double-strand break repair created_by: pfey creation_date: 2015-02-12T16:01:50Z [Term] id: DDPHENO:0000250 name: increased single-strand break repair def: "Increased tolerance of the normal, usual, or expected events in single-strand break repair of DNA." [DDB:pf] is_a: DDPHENO:0000243 ! aberrant single-strand break repair created_by: pfey creation_date: 2015-02-12T16:02:13Z [Term] id: DDPHENO:0000251 name: aberrant regulation of mitochondrial membrane potential def: "Deviation from the normal, usual, or expected events during regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf] is_a: DDPHENO:0001008 ! aberrant cellular process created_by: pfey creation_date: 2015-03-04T16:27:33Z [Term] id: DDPHENO:0000252 name: aberrant positive regulation of mitochondrial membrane potential def: "Deviation from the normal, usual, or expected events during positive regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf] is_a: DDPHENO:0000251 ! aberrant regulation of mitochondrial membrane potential created_by: pfey creation_date: 2015-03-04T17:40:26Z [Term] id: DDPHENO:0000253 name: aberrant negative regulation of mitochondrial membrane potential def: "Deviation from the normal, usual, or expected events during negative regulation of the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [DDB:pf] is_a: DDPHENO:0000251 ! aberrant regulation of mitochondrial membrane potential created_by: pfey creation_date: 2015-03-04T17:41:03Z [Term] id: DDPHENO:0000254 name: aberrant cell motility in response to calcium ion def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration of calcium." [DDB:pf] synonym: "aberrant chemotaxis to Ca2+" EXACT [] synonym: "aberrant chemotaxis to calcium" EXACT [] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis created_by: pfey creation_date: 2015-04-13T16:41:24Z [Term] id: DDPHENO:0000255 name: obsolete aberrant potassium-dependent chemotaxis to cAMP def: "OBSOLETE. Deviation from the normal, usual, or expected events during potassium-dependent chemotaxis to cAMP." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-04-13T16:57:18Z [Term] id: DDPHENO:0000256 name: obsolete abolished potassium-dependent chemotaxis to cAMP def: "OBSOLETE. Complete inability for potassium-dependent chemotaxis to cAMP." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-04-13T17:39:42Z [Term] id: DDPHENO:0000257 name: abolished cell motility in response to calcium ion def: "Complete inability for chemotaxis in response to calcium." [DDB:pf] synonym: "abolished chemotaxis to Ca2+" EXACT [] synonym: "abolished chemotaxis to calcium" EXACT [] is_a: DDPHENO:0000254 ! aberrant cell motility in response to calcium ion created_by: pfey creation_date: 2015-04-13T17:42:45Z [Term] id: DDPHENO:0000258 name: aberrant defence response to bacterium alt_id: DDPHENO:0000277 def: "Deviation from the normal, usual, or expected events during defence response to bacterium." [DDB:pf] comment: Pathogenic bacteria are defined as being pathogens for humans, though in the any specific study a strain or species less virulent for humans may have been used. synonym: "aberrant infection rate by pathogenic bacterium" NARROW [] is_a: DDPHENO:0001505 ! aberrant cellular defence response created_by: pfey creation_date: 2015-05-05T14:26:26Z [Term] id: DDPHENO:0000260 name: decreased cell migration to prestalk region def: "Reduction in extent, amount, or degree of cell migration to prestalk region during the slug stage." [DDB:pg] synonym: "decreased sorting to prestalk region" EXACT [] is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region [Term] id: DDPHENO:0000261 name: obsolete abolished prestalk cell differentiation in response to DIF-1 def: "OBSOLETE. Complete inability for prestalk cell differentiation in response to DIF-1." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000262 name: decreased prestalk O cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk O cells." [DDB:pf] synonym: "decreased number of prestalk O cells" RELATED [] synonym: "decreased pstO cell differentiation" EXACT [] is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation is_a: DDPHENO:0001024 ! aberrant prestalk O cell differentiation [Term] id: DDPHENO:0000263 name: aberrant nucleus morphology def: "Deviation from the normal, usual, or expected morphology of the nucleus." [DDB:pg] synonym: "aberrant nuclear morphology" EXACT [] is_a: DDPHENO:0001002 ! aberrant organelle morphology is_a: DDPHENO:0001536 ! aberrant nucleus organization [Term] id: DDPHENO:0000264 name: aberrant cell motility def: "Deviation from the normal, usual, or expected events during cell motility." [DDB:pg] comment: Child of GO:0006928 : cell motility. is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0000265 name: aberrant myosin II filament organization def: "Deviation from the normal, usual, or expected events during myosin II organization." [DDB:pg] synonym: "aberrant myosin II organization" EXACT [] is_a: DDPHENO:0000236 ! aberrant cell morphogenesis [Term] id: DDPHENO:0000269 name: increased basal disc size def: "Increase in relative or proportionate dimensions of the basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0000270 name: obsolete increased number of tubular mitochondria def: "OBSOLETE. Quantitative increase in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000271 name: decreased number of mitochondria def: "Quantitative reduction in mitochondria." [DDB:pg] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization [Term] id: DDPHENO:0000272 name: increased number of mitochondria def: "Quantitative increase in mitochondria." [DDB:pg] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization [Term] id: DDPHENO:0000273 name: obsolete decreased SDF production def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF production." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000274 name: obsolete abolished SDF production def: "OBSOLETE. Complete inability for SDF production." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000276 name: obsolete increased resistance to DNA-damaging agents def: "OBSOLETE. Increased tolerance of the normal, usual, or expected events in the presence of DNA damaging agents." [DDB:pf] synonym: "decreased sensitivity to DNA-damaging agents" EXACT [] is_obsolete: true [Term] id: DDPHENO:0000278 name: increased defence response to bacterium def: "Increase in extent, amount, or degree of the def defence ense response to bacterium." [DDB:pf] is_a: DDPHENO:0000258 ! aberrant defence response to bacterium created_by: pfey creation_date: 2015-05-05T14:58:43Z [Term] id: DDPHENO:0000279 name: decreased defence response to bacterium def: "Reduction in extent, amount, or degree for defence response to bacterium." [DDB:pf] is_a: DDPHENO:0000258 ! aberrant defence response to bacterium created_by: pfey creation_date: 2015-05-05T14:59:45Z [Term] id: DDPHENO:0000280 name: aberrant defence response to fungus def: "Deviation from the normal, usual, or expected events defence response to fungus." [DDB:pf] synonym: "aberrant defence response to yeast" NARROW [] is_a: DDPHENO:0001505 ! aberrant cellular defence response created_by: pfey creation_date: 2015-05-05T16:05:13Z [Term] id: DDPHENO:0000281 name: obsolete aberrant infection rate by a yeast def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true created_by: pfey creation_date: 2015-05-05T16:06:20Z [Term] id: DDPHENO:0000282 name: increased defence response to fungus def: "Increase in extent, amount, or degree of the defence response to fungus." [DDB:pf] synonym: "increased defence response to yeast" NARROW [] is_a: DDPHENO:0000280 ! aberrant defence response to fungus created_by: pfey creation_date: 2015-05-05T16:07:54Z [Term] id: DDPHENO:0000283 name: decreased defence response to fungus def: "Reduction in extent, amount, or degree for defence response to fungus." [DDB:pf] synonym: "decreased defence response to yeast" NARROW [] is_a: DDPHENO:0000280 ! aberrant defence response to fungus created_by: pfey creation_date: 2015-05-05T16:08:09Z [Term] id: DDPHENO:0000284 name: aberrant defence response to Gram-positive bacterium def: "Deviation from the normal, usual, or expected events during defence response to Gram-positive bacterium, often after infection." [DDB:pf, PMID:23664307] synonym: "aberrant defence response to pathogenic Gram-positive bacterium" NARROW [] is_a: DDPHENO:0000258 ! aberrant defence response to bacterium created_by: pfey creation_date: 2015-05-05T16:38:31Z [Term] id: DDPHENO:0000285 name: increased defence response to Gram-positive bacterium def: "Increase in extent, amount, or degree of the defence response to Gram-positive bacterium, often after infection." [DDB:pf] synonym: "increased defence response to pathogenic Gram-positive bacterium" NARROW [] is_a: DDPHENO:0000278 ! increased defence response to bacterium is_a: DDPHENO:0000284 ! aberrant defence response to Gram-positive bacterium created_by: pfey creation_date: 2015-05-05T16:42:05Z [Term] id: DDPHENO:0000286 name: decreased defence response to Gram-positive bacterium def: "Reduction in extent, amount, or degree for defence response to Gram-positive bacterium, often after infection." [DDB:pf] synonym: "decreased defence response to pathogenic Gram-positive bacterium" NARROW [] is_a: DDPHENO:0000279 ! decreased defence response to bacterium is_a: DDPHENO:0000284 ! aberrant defence response to Gram-positive bacterium created_by: pfey creation_date: 2015-05-05T16:42:37Z [Term] id: DDPHENO:0000287 name: aberrant defence response to Gram-negative bacterium def: "Deviation from the normal, usual, or expected events defence response to Gram-negative bacterium, often after infection." [DDB:pf, PMID:23664307] synonym: "aberrant defence response to pathogenic Gram-negative bacterium" NARROW [] is_a: DDPHENO:0000258 ! aberrant defence response to bacterium created_by: pfey creation_date: 2015-05-05T16:48:58Z [Term] id: DDPHENO:0000288 name: increased defence response to Gram-negative bacterium def: "Increase in extent, amount, or degree of the defence response to Gram-negative bacterium, often after infection." [DDB:pf] synonym: "increased defence response to pathogenic Gram-negative bacterium" NARROW [] is_a: DDPHENO:0000278 ! increased defence response to bacterium is_a: DDPHENO:0000287 ! aberrant defence response to Gram-negative bacterium created_by: pfey creation_date: 2015-05-05T16:49:27Z [Term] id: DDPHENO:0000289 name: decreased defence response to Gram-negative bacterium def: "Reduction in extent, amount, or degree of the defence response to Gram-negative bacterium, often after infection." [DDB:pf] synonym: "decreased defence response to pathogenic Gram-negative bacterium" NARROW [] is_a: DDPHENO:0000279 ! decreased defence response to bacterium is_a: DDPHENO:0000287 ! aberrant defence response to Gram-negative bacterium created_by: pfey creation_date: 2015-05-05T16:49:39Z [Term] id: DDPHENO:0000290 name: abolished defence response to Gram-positive bacterium def: "Complete inability for defence response to Gram-positive bacterium, often after infection." [DDB:pf] synonym: "abolished defence response to pathogenic Gram-positive bacterium" NARROW [] is_a: DDPHENO:0000284 ! aberrant defence response to Gram-positive bacterium is_a: DDPHENO:0000491 ! abolished defence response to bacterium created_by: pfey creation_date: 2015-05-05T16:57:55Z [Term] id: DDPHENO:0000291 name: abolished defence response to Gram-negative bacterium def: "Complete inability for defence response to Gram-negative bacterium, often after infection." [DDB:pf] synonym: "abolished defence response to pathogenic Gram-negative bacterium" NARROW [] is_a: DDPHENO:0000287 ! aberrant defence response to Gram-negative bacterium is_a: DDPHENO:0000491 ! abolished defence response to bacterium created_by: pfey creation_date: 2015-05-05T16:58:28Z [Term] id: DDPHENO:0000292 name: obsolete decreased infection rate by Mycobacterium marinum def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true created_by: pfey creation_date: 2015-05-05T17:02:13Z [Term] id: DDPHENO:0000293 name: obsolete increased infection rate by Mycobacterium marinum def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true created_by: pfey creation_date: 2015-05-05T17:03:59Z [Term] id: DDPHENO:0000294 name: aberrant protein binding def: "Deviation from the normal, usual, or expected binding of a protein." [DDB:pf] is_a: DDPHENO:0001255 ! aberrant binding created_by: pfey creation_date: 2015-05-20T17:42:41Z [Term] id: DDPHENO:0000295 name: abolished protein binding def: "Complete absence of protein binding." [DDB:pf] is_a: DDPHENO:0000294 ! aberrant protein binding created_by: pfey creation_date: 2015-05-20T17:43:34Z [Term] id: DDPHENO:0000296 name: decreased protein binding def: "A reduction in extent, amount, or degree of binding to a protein." [DDB:pf] is_a: DDPHENO:0000294 ! aberrant protein binding created_by: pfey creation_date: 2015-05-20T17:44:30Z [Term] id: DDPHENO:0000297 name: increased protein binding def: "Increased in extent, amount, or degree of binding a protein." [DDB:pf] is_a: DDPHENO:0000294 ! aberrant protein binding created_by: pfey creation_date: 2015-05-20T17:44:44Z [Term] id: DDPHENO:0000298 name: aberrant lipid binding def: "Deviation from the normal, usual, or expected binding a lipid." [DDB:pf] is_a: DDPHENO:0001255 ! aberrant binding created_by: pfey creation_date: 2015-05-20T17:46:27Z [Term] id: DDPHENO:0000300 name: decreased gene expression alt_id: DDPHENO:0000174 alt_id: DDPHENO:0000189 alt_id: DDPHENO:0000220 alt_id: DDPHENO:0000267 def: "Reduction in extent, amount, or degree of gene expression." [DDB:pg] synonym: "merged_decreased expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_decreased expression of prespore genes" NARROW [DDB:kp] synonym: "merged_decreased expression of prestalk genes" NARROW [DDB:kp] synonym: "merged_decreased expression of spore genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0000301 name: increased gene expression alt_id: DDPHENO:0000114 alt_id: DDPHENO:0000224 alt_id: DDPHENO:0000266 alt_id: DDPHENO:0000372 def: "Increase in extent, amount, or degree of gene expression." [DDB:pg] synonym: "merged_increased discoidin level" NARROW [DDB:kp] synonym: "merged_increased expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_increased expression of prespore genes" NARROW [DDB:kp] synonym: "merged_increased expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0000302 name: abolished vegetative growth alt_id: DDPHENO:0000221 alt_id: DDPHENO:0000259 alt_id: DDPHENO:0000275 alt_id: DDPHENO:0000458 alt_id: DDPHENO:0001060 def: "Complete inability for cells to proliferate." [DDB:pg] synonym: "abolished asexual reproduction" EXACT [] synonym: "abolished growth in acidic medium" NARROW [] synonym: "abolished growth in axenic medium" NARROW [] synonym: "abolished growth in suspension" NARROW [] synonym: "abolished growth on bacterial plates" NARROW [] synonym: "inviable" RELATED [] is_a: DDPHENO:0001084 ! aberrant vegetative growth [Term] id: DDPHENO:0000304 name: increased membrane ruffling def: "Increase in extent, amount, or degree of membrane ruffling." [DDB:pg] synonym: "increased ruffle assembly" EXACT [] is_a: DDPHENO:0000042 ! aberrant membrane ruffling [Term] id: DDPHENO:0000305 name: obsolete abolished down-regulation of growth phase genes def: "OBSOLETE. Complete inability for down-regulation of growth phase genes." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000306 name: aberrant cell migration to prestalk region def: "Deviation from the normal, usual, or expected cell migration to the prestalk region." [DDB:pf] synonym: "aberrant sorting to prestalk region" EXACT [] is_a: DDPHENO:0001014 ! aberrant slug development created_by: pfey creation_date: 2015-06-16T17:41:25Z [Term] id: DDPHENO:0000307 name: obsolete abolished SDF-1 production def: "OBSOLETE. Complete inability for SDF-1 production." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T14:01:18Z [Term] id: DDPHENO:0000308 name: obsolete abolished SDF-2 production def: "OBSOLETE. Complete inability for SDF-2 production." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T14:01:46Z [Term] id: DDPHENO:0000309 name: obsolete decreased SDF-1 production def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF-1 production." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T14:02:06Z [Term] id: DDPHENO:0000310 name: obsolete decreased SDF-2 production def: "OBSOLETE. Reduction in extent, amount or accumulation of SDF-2 production." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T14:03:53Z [Term] id: DDPHENO:0000311 name: aberrant MPBD level def: "Deviation from the normal, usual, or expected during MPBD biosynthesis, a polyketide." [DDB:pf] synonym: "aberrant 4-methyl5-pentylbenzene-1,3 diol production" EXACT [] synonym: "aberrant MPBD biosynthesis" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2015-06-17T14:37:07Z [Term] id: DDPHENO:0000312 name: abolished MPBD level def: "Complete inability for the biosynthesis of MPBD, a polyketide." [DDB:pf] synonym: "abolished 4-methyl5-pentylbenzene-1,3-diol production" EXACT [] synonym: "abolished MPBD biosynthesis" EXACT [] is_a: DDPHENO:0000311 ! aberrant MPBD level created_by: pfey creation_date: 2015-06-17T14:39:34Z [Term] id: DDPHENO:0000313 name: decreased MPBD level def: "Reduction in extent, amount, or degree of MPBD biosynthesis, a polyketide." [DDB:pf] synonym: "decreased 4-methyl5-pentylbenzene-1,3 diol production" EXACT [] synonym: "decreased MPBD biosynthesis" EXACT [] is_a: DDPHENO:0000311 ! aberrant MPBD level created_by: pfey creation_date: 2015-06-17T14:40:21Z [Term] id: DDPHENO:0000314 name: aberrant polyketide metabolic process def: "Deviation from the normal, usual, or expected during the polyketide metabolic process." [DDB:pf] synonym: "aberrant response to 4-methyl5-pentylbenzene-1,3 diol (MPBD)" NARROW [] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus created_by: pfey creation_date: 2015-06-17T17:18:33Z [Term] id: DDPHENO:0000315 name: abolished polyketide metabolic process def: "Complete inability for polyketide metabolic process." [DDB:pf] synonym: "abolished response to 4-methyl5-pentylbenzene-1,3 diol (MPBD)" NARROW [] is_a: DDPHENO:0000314 ! aberrant polyketide metabolic process is_a: DDPHENO:0000693 ! abolished response to biotic stimulus created_by: pfey creation_date: 2015-06-17T17:20:55Z [Term] id: DDPHENO:0000316 name: obsolete aberrant response to SDF-1 def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to SDF-1." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T17:27:25Z [Term] id: DDPHENO:0000317 name: obsolete abolished response to SDF-1 def: "OBSOLETE. Complete inability for response to SDF-1." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2015-06-17T17:29:11Z [Term] id: DDPHENO:0000318 name: abolished development of tipped mound def: "Complete inability to form a tipped mound during development." [DDB:pf] synonym: "abolished sorocarp development of tipped mound" EXACT [] synonym: "abolished tip formation" RELATED [] is_a: DDPHENO:0001431 ! aberrant development of tipped mound created_by: pfey creation_date: 2015-10-08T17:23:04Z [Term] id: DDPHENO:0000320 name: aberrant polysaccharide binding def: "Deviation from the normal, usual, or expected binding a polysaccharide." [DDB:pf] is_a: DDPHENO:0001255 ! aberrant binding created_by: pfey creation_date: 2015-12-17T17:14:53Z [Term] id: DDPHENO:0000321 name: aberrant cellulose binding def: "Deviation from the normal, usual, or expected binding of cellulose." [DDB:pf] is_a: DDPHENO:0000320 ! aberrant polysaccharide binding created_by: pfey creation_date: 2015-12-17T17:15:32Z [Term] id: DDPHENO:0000322 name: abolished cellulose binding def: "Complete absence of cellulose binding." [DDB:pf] is_a: DDPHENO:0000321 ! aberrant cellulose binding created_by: pfey creation_date: 2015-12-17T17:16:25Z [Term] id: DDPHENO:0000323 name: decreased cellulose binding def: "A reduction in extent, amount, or degree of binding to cellulose." [DDB:pf] is_a: DDPHENO:0000321 ! aberrant cellulose binding created_by: pfey creation_date: 2015-12-17T17:16:44Z [Term] id: DDPHENO:0000324 name: aberrant cyclic nucleotide binding def: "Deviation from the normal, usual, or expected binding of a cyclic nucleotide." [DDB:pf] is_a: DDPHENO:0000327 ! aberrant small molecule binding created_by: pfey creation_date: 2015-12-17T17:18:19Z [Term] id: DDPHENO:0000325 name: decreased lipid binding def: "A reduction in extent, amount, or degree of binding to a lipid." [DDB:pf] is_a: DDPHENO:0000298 ! aberrant lipid binding created_by: pfey creation_date: 2015-12-17T17:50:09Z [Term] id: DDPHENO:0000326 name: abolished lipid binding def: "Complete absence of lipid binding." [DDB:pf] is_a: DDPHENO:0000298 ! aberrant lipid binding created_by: pfey creation_date: 2015-12-17T17:50:52Z [Term] id: DDPHENO:0000327 name: aberrant small molecule binding def: "Deviation from the normal, usual, or expected binding a small molecule." [DDB:pf] comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids. is_a: DDPHENO:0001255 ! aberrant binding created_by: pfey creation_date: 2015-12-17T17:52:38Z [Term] id: DDPHENO:0000328 name: abolished small molecule binding def: "Complete absence of small molecule binding." [DDB:pf] comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids. is_a: DDPHENO:0000327 ! aberrant small molecule binding created_by: pfey creation_date: 2015-12-17T17:53:02Z [Term] id: DDPHENO:0000329 name: decreased small molecule binding def: "A reduction in extent, amount, or degree of binding to a small molecule." [DDB:pf] comment: Small molecules include monosaccharides but exclude disaccharides and polysaccharides; includes organic cyclic compounds and single amino acids. is_a: DDPHENO:0000327 ! aberrant small molecule binding created_by: pfey creation_date: 2015-12-17T17:53:44Z [Term] id: DDPHENO:0000330 name: abolished cAMP binding def: "Complete absence of cAMP binding." [DDB:pf] is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding is_a: DDPHENO:0000328 ! abolished small molecule binding created_by: pfey creation_date: 2016-04-21T16:35:28Z [Term] id: DDPHENO:0000331 name: aberrant folic acid binding def: "Deviation from the normal, usual, or expected binding to folic acid." [DDB:pf] is_a: DDPHENO:0000327 ! aberrant small molecule binding created_by: pfey creation_date: 2016-04-21T16:37:34Z [Term] id: DDPHENO:0000332 name: decreased folic acid binding def: "A reduction in extent, amount, or degree of binding to folic acid." [DDB:pf] is_a: DDPHENO:0000329 ! decreased small molecule binding is_a: DDPHENO:0000331 ! aberrant folic acid binding created_by: pfey creation_date: 2016-04-21T16:39:46Z [Term] id: DDPHENO:0000333 name: increased folic acid binding def: "Increased in extent, amount, or degree of binding to folic acid." [DDB:pf] is_a: DDPHENO:0000331 ! aberrant folic acid binding created_by: pfey creation_date: 2016-04-21T16:40:08Z [Term] id: DDPHENO:0000334 name: abolished folic acid binding def: "Complete absence of folic acid binding." [DDB:pf] is_a: DDPHENO:0000328 ! abolished small molecule binding is_a: DDPHENO:0000331 ! aberrant folic acid binding created_by: pfey creation_date: 2016-04-21T16:42:34Z [Term] id: DDPHENO:0000335 name: obsolete aberrant electrotaxis def: "OBSOLETE. Deviation from the normal, usual, or expected events during the locomotory response to an electrical field." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-06-14T12:24:22Z [Term] id: DDPHENO:0000336 name: obsolete decreased electrotaxis def: "Obsolete Reduction in extent, amount, or degree of electrotaxis rate during the locomotory response to an electrical field." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-06-14T12:26:21Z [Term] id: DDPHENO:0000337 name: obsolete increased electrotaxis def: "OBSOLETE. Increase in extent, amount, or degree of electrotaxis rate during the locomotory response to an electrical field." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-06-14T12:26:37Z [Term] id: DDPHENO:0000338 name: obsolete abolished electrotaxis def: "OBSOLETE. Complete inability for electrotaxis in response to an electrical field." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-06-14T12:26:51Z [Term] id: DDPHENO:0000339 name: obsolete aberrant response to SDF-2 def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to SDF-2." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-07-18T10:38:21Z [Term] id: DDPHENO:0000340 name: obsolete abolished response to SDF-2 def: "OBSOLETE. Complete inability for response to SDF-2." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-07-18T10:39:38Z [Term] id: DDPHENO:0000341 name: obsolete aberrant membrane organization during endocytosis def: "OBSOLETE. Deviation from the normal, usual, or expected plasma membrane organization during endocytosis." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-09-07T17:43:13Z [Term] id: DDPHENO:0000342 name: decreased plasma membrane organization def: "Decrease from the normal, usual, or expected plasma membrane organization." [DDB:pf] is_a: DDPHENO:0000039 ! aberrant plasma membrane organization created_by: pfey creation_date: 2016-09-07T17:44:39Z [Term] id: DDPHENO:0000343 name: obsolete abolished activation of GTPase activity def: "OBSOLETE Complete inability for activation of GTPase activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-10-07T13:24:37Z [Term] id: DDPHENO:0000344 name: obsolete decreased activation of GTPase activity def: "OBSOLETE Reduction in extent, amount, or degree of activation GTPase activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-10-07T13:25:29Z [Term] id: DDPHENO:0000345 name: obsolete increased activation of GTPase activity def: "OBSOLETE Increase in extent, amount, or degree of activation of GTPase activity." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2016-10-07T13:25:54Z [Term] id: DDPHENO:0000346 name: decreased protein kinase activity def: "Reduction in extent, amount, or degree of protein kinase activity." [DDB:pf] is_a: DDPHENO:0001257 ! decreased catalytic activity created_by: pfey creation_date: 2016-10-10T17:14:11Z [Term] id: DDPHENO:0000347 name: abolished protein kinase activity def: "Complete absence of protein kinase activity." [DDB:pf] is_a: DDPHENO:0001289 ! abolished catalytic activity created_by: pfey creation_date: 2016-10-10T17:17:41Z [Term] id: DDPHENO:0000348 name: increased protein kinase activity def: "Increase in extent, amount, or degree of protein kinase activity." [DDB:pf] is_a: DDPHENO:0001256 ! increased catalytic activity created_by: pfey creation_date: 2016-10-10T17:18:44Z [Term] id: DDPHENO:0000349 name: aberrant calcium-mediated signaling def: "Deviation from the normal, usual, or expected events during calcium signaling." [DDB:pf] synonym: "aberrant Ca2+ signaling" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2016-10-11T12:46:12Z [Term] id: DDPHENO:0000350 name: aberrant macropinocytosis def: "Deviation from the normal, usual, or expected events during macropinocytosis." [DDB:pf] is_a: DDPHENO:0001007 ! aberrant pinocytosis created_by: pfey creation_date: 2016-10-11T13:11:24Z [Term] id: DDPHENO:0000351 name: abolished macropinocytosis def: "Complete inability to perform macropinocytosis." [DDB:pf] is_a: DDPHENO:0000350 ! aberrant macropinocytosis created_by: pfey creation_date: 2016-10-11T13:13:56Z [Term] id: DDPHENO:0000352 name: decreased macropinocytosis def: "Reduction in extent, amount, or degree of macropinocytosis." [DDB:pf] is_a: DDPHENO:0000350 ! aberrant macropinocytosis created_by: pfey creation_date: 2016-10-11T13:14:51Z [Term] id: DDPHENO:0000353 name: aberrant endosomal transport def: "Deviation from the normal, usual, or expected events during endosomal transport." [DDB:pf] is_a: DDPHENO:0001047 ! aberrant transport created_by: pfey creation_date: 2017-02-08T15:22:57Z [Term] id: DDPHENO:0000354 name: aberrant endocytic recycling def: "Deviation from the normal, usual, or expected events during endocytic recycling." [DDB:pf] synonym: "aberrant retrograde transport of endocytic vesicles" RELATED [] is_a: DDPHENO:0000353 ! aberrant endosomal transport created_by: pfey creation_date: 2017-02-08T15:26:07Z [Term] id: DDPHENO:0000355 name: abolished endocytic recycling def: "Complete inability of endocytic recycling." [DDB:pf] synonym: "abolished retrograde transport of endocytic vesicles" RELATED [] is_a: DDPHENO:0000354 ! aberrant endocytic recycling created_by: pfey creation_date: 2017-02-08T15:27:20Z [Term] id: DDPHENO:0000356 name: decreased endocytic recycling def: "Reduction in extent, amount, or degree of endocytic recycling." [DDB:pf] synonym: "decreased retrograde transport of endocytic vesicles" RELATED [] is_a: DDPHENO:0000354 ! aberrant endocytic recycling created_by: pfey creation_date: 2017-02-08T15:29:59Z [Term] id: DDPHENO:0000357 name: increased endocytic recycling def: "Increase in extent, amount, or degree of endocytic recycling." [DDB:pf] synonym: "increased retrograde transport of endocytic vesicles" RELATED [] is_a: DDPHENO:0000354 ! aberrant endocytic recycling created_by: pfey creation_date: 2017-02-08T15:31:07Z [Term] id: DDPHENO:0000358 name: aberrant response to cAMP def: "Deviation from the normal, usual, or expected events during the response to cAMP." [DDB:pf] is_a: DDPHENO:0001038 ! aberrant extracellular cAMP signaling pathway created_by: pfey creation_date: 2017-02-24T10:45:56Z [Term] id: DDPHENO:0000359 name: increased response to cAMP def: "Increase in extent, amount, or degree of response to cAMP." [DDB:pf] is_a: DDPHENO:0000358 ! aberrant response to cAMP created_by: pfey creation_date: 2017-02-24T10:46:56Z [Term] id: DDPHENO:0000360 name: decreased response to cAMP def: "Reduction in the response to cAMP." [DDB:pf] is_a: DDPHENO:0000358 ! aberrant response to cAMP created_by: pfey creation_date: 2017-02-24T10:47:13Z [Term] id: DDPHENO:0000361 name: abolished response to cAMP def: "Complete inability to respond to cAMP." [DDB:pf] is_a: DDPHENO:0000358 ! aberrant response to cAMP created_by: pfey creation_date: 2017-02-24T10:48:18Z [Term] id: DDPHENO:0000362 name: aberrant response to nocodazole def: "Deviation from the normal, usual, or expected events during the response to nocodazole." [DDB:pf] is_a: DDPHENO:0000040 ! aberrant response to chemical created_by: pfey creation_date: 2017-03-07T16:39:49Z [Term] id: DDPHENO:0000363 name: increased resistance to nocodazole def: "Increase in extent, amount, or degree of resistance to nocodazole." [DDB:pf] is_a: DDPHENO:0000362 ! aberrant response to nocodazole created_by: pfey creation_date: 2017-03-07T16:41:38Z [Term] id: DDPHENO:0000364 name: increased macropinocytosis def: "Increase in extent, amount, or degree of macropinocytosis." [DDB:pf] is_a: DDPHENO:0000350 ! aberrant macropinocytosis created_by: pfey creation_date: 2017-03-13T10:24:42Z [Term] id: DDPHENO:0000365 name: aberrant prestalk gene expression def: "Deviation from the normal, usual, or expected expression of prestalk genes." [DDB:pf] synonym: "aberrant prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0001113 ! aberrant gene expression created_by: pfey creation_date: 2017-03-23T09:52:00Z [Term] id: DDPHENO:0000366 name: precocious prestalk gene expression def: "Early onset or faster progression of prestalk cell specific gene expression." [DDB:pf] synonym: "precocious prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0000365 ! aberrant prestalk gene expression is_a: DDPHENO:0001116 ! precocious gene expression created_by: pfey creation_date: 2017-03-23T09:53:39Z [Term] id: DDPHENO:0000367 name: obsolete mislocalized prestalk gene expression def: "OBSOLETE. Prestalk gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2017-03-23T13:29:35Z [Term] id: DDPHENO:0000368 name: delayed prestalk gene expression def: "Late onset or slower progression of prestalk cell specific gene expression." [DDB:pf] synonym: "delayed prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0000365 ! aberrant prestalk gene expression is_a: DDPHENO:0001115 ! delayed gene expression created_by: pfey creation_date: 2017-03-23T14:54:09Z [Term] id: DDPHENO:0000369 name: decreased prestalk gene expression def: "Reduction in extent, amount, or degree of prestalk cell specific gene expression." [DDB:pf] synonym: "decreased prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0000300 ! decreased gene expression is_a: DDPHENO:0000365 ! aberrant prestalk gene expression created_by: pfey creation_date: 2017-03-23T14:54:56Z [Term] id: DDPHENO:0000370 name: aberrant prespore gene expression def: "Deviation from the normal, usual, or expected prespore cell specific gene expression." [DDB:pf] synonym: "aberrant prespore cell specific gene expression" EXACT [] is_a: DDPHENO:0001113 ! aberrant gene expression created_by: pfey creation_date: 2017-03-23T15:35:42Z [Term] id: DDPHENO:0000371 name: decreased prespore gene expression def: "Reduction in extent, amount, or degree of prespore cell specific gene expression." [DDB:pf] synonym: "decreased prespore cell specific gene expression" EXACT [] is_a: DDPHENO:0000300 ! decreased gene expression is_a: DDPHENO:0000370 ! aberrant prespore gene expression created_by: pfey creation_date: 2017-03-23T15:36:45Z [Term] id: DDPHENO:0000375 name: delayed prespore gene expression def: "Late onset or slower progression of prespore cell specific gene expression." [DDB:pf] synonym: "delayed prespore cell specific gene expression" EXACT [] is_a: DDPHENO:0000370 ! aberrant prespore gene expression is_a: DDPHENO:0001115 ! delayed gene expression created_by: pfey creation_date: 2017-03-23T15:38:40Z [Term] id: DDPHENO:0000376 name: abolished filopodium formation def: "Complete inability to form filopodia." [DDB:pf] synonym: "abolished filopodium assembly" EXACT [] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000377 name: increased filopodium formation def: "Increase in extent, amount, or degree of formation of filopodia." [DDB:pg] synonym: "increased filopodium assembly" EXACT [] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000378 name: decreased lateral pseudopodium retraction def: "Reduction in extent, amount, or degree of suppression or retraction of lateral pseudopods." [DD:pg] is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation [Term] id: DDPHENO:0000379 name: decreased vegetative cell size def: "Reduction in relative or proportionate dimensions of the vegetative cell." [DDB:pf] synonym: "decreased vegetative amoebae size" EXACT [] xref: PMID:18366659 "DDANAT:0000002" is_a: DDPHENO:0000236 ! aberrant cell morphogenesis [Term] id: DDPHENO:0000381 name: decreased resistance to TMB-8 def: "Decreased tolerance of the normal, usual, or expected events towards TMB-8." [DDB:pf] synonym: "increased sensitivity to 3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester" EXACT [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0000382 name: obsolete aberrant morphology def: "OBSOLETE. Deviation from the normal, usual, or expected events during morphogenesis." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0000383 name: decreased stalk length def: "Having a relative short stalk." [DDB:pg] synonym: "short stalk" EXACT [] xref: PATO:0000574 is_a: DDPHENO:0000510 ! aberrant stalk morphology [Term] id: DDPHENO:0000384 name: aberrant sorus morphology def: "Deviation from the normal, usual, or expected morphology of the sorus." [DDB:pg] synonym: "aberrant spore head morphology" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis [Term] id: DDPHENO:0000385 name: abolished cytokinesis def: "Complete inability for cytokinesis." [DDB:pg] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0000387 name: abolished prespore cell division def: "Complete inability for division of prespore cells." [DDB:pg] is_a: DDPHENO:0001014 ! aberrant slug development [Term] id: DDPHENO:0000388 name: obsolete abolished vacuolation def: "OBSOLETE. Complete inability for vacuolation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000389 name: increased sorus size def: "Increase in relative or proportionate dimensions of the sorus." [DDB:pg] synonym: "large sori" EXACT [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0000390 name: aberrant sorus color def: "Deviation from the normal, usual, or expected sorus color." [DDB:pf] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000391 name: obsolete partial suppression of tagB mutation def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000392 name: decreased establishment of cell polarity def: "Reduction in extent, amount, or degree of cell polarity establishment." [DDB:pg] synonym: "decreased cell polarity" EXACT [] is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity [Term] id: DDPHENO:0000393 name: decreased cell-substrate adhesion def: "Reduction in extent, amount, or degree of cell-substrate adhesion." [DDB:pg] synonym: "decreased substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000394 name: decreased growth rate alt_id: DDPHENO:0000202 alt_id: DDPHENO:0000373 alt_id: DDPHENO:0000396 alt_id: DDPHENO:0000416 alt_id: DDPHENO:0000417 alt_id: DDPHENO:0000435 alt_id: DDPHENO:0000436 alt_id: DDPHENO:0000467 alt_id: DDPHENO:0000511 alt_id: DDPHENO:0000534 alt_id: DDPHENO:0001096 def: "Reduction in extent, amount, or degree of cell proliferation." [DDB:pf] synonym: "decreased asexual reproduction" EXACT [] synonym: "decreased growth rate in bacterial suspension" NARROW [] synonym: "decreased growth rate in liquid medium on solid surfaces" NARROW [] synonym: "decreased growth rate in suspension" NARROW [] synonym: "decreased growth rate in suspension at low temperature" NARROW [] synonym: "decreased growth rate on bacterial plates" NARROW [] synonym: "decreased growth rate under Ca2+ stress" NARROW [] synonym: "decreased growth rates on solid surfaces" NARROW [] synonym: "merged_decreased growth rate at low cell density" NARROW [] synonym: "merged_decreased growth rate in suspension in the presence of lithium" NARROW [] synonym: "merged_decreased growth rate in the presence of gossypol" NARROW [] synonym: "merged_decreased growth rate in the presence of ion chelators" NARROW [] is_a: DDPHENO:0001084 ! aberrant vegetative growth [Term] id: DDPHENO:0000395 name: obsolete decreased activation of protein kinase B def: "OBSOLETE. Reduction in extent, amount or degree of activation of protein kinase B." [DDB:pg] comment: Not sure this is legitimate. See SF for an item on PKB; I think it's a gee product. is_obsolete: true [Term] id: DDPHENO:0000397 name: aberrant cytoskeleton organization def: "Deviation from the normal, usual, or expected events during cytoskeleton organization." [DDB:pg] is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0000398 name: obsolete no synthetic interaction observed between rasS and gefB def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000399 name: decreased rate of endocytosis def: "Reduction in extent, amount, or degree of endocytosis." [DDB:pg] is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0000400 name: increased chemotaxis rate def: "Increase in extent, amount, or degree of chemotaxis rate during the locomotory response to a chemical concentration gradient." [DDB:kp] is_a: DDPHENO:0000116 ! increased cell motility is_a: DDPHENO:0001122 ! aberrant chemotaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0000401 name: increased resistance to cisplatin def: "Increase in extent, amount, or degree of resistance to cisplatin." [DDB:pf] is_a: DDPHENO:0001456 ! aberrant response to cisplatin [Term] id: DDPHENO:0000402 name: obsolete increased intracellular cAMP level def: "OBSOLETE. Increase in extent, amount, or degree of intracellular cAMP level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000403 name: increased prestalk gene expression def: "Increase in extent, amount, or degree of prestalk cell specific gene expression." [DDB:pf] synonym: "increased prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0000301 ! increased gene expression is_a: DDPHENO:0000365 ! aberrant prestalk gene expression created_by: pfey creation_date: 2017-03-23T15:39:41Z [Term] id: DDPHENO:0000404 name: increased prespore gene expression def: "Increase in extent, amount, or degree for prespore cell specific gene expression." [DDB:pf] synonym: "increased prespore gene cell specific expression" EXACT [] is_a: DDPHENO:0000301 ! increased gene expression is_a: DDPHENO:0000370 ! aberrant prespore gene expression created_by: pfey creation_date: 2017-03-23T15:54:24Z [Term] id: DDPHENO:0000405 name: increased phagocytosis def: "Increase in extent, amount, or degree of phagocytosis." [DDB:pg] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0000406 name: increased vegetative cell size def: "Increase in relative or proportionate dimensions of the vegetative cell." [DDB:pf] synonym: "increased vegetative amoebae size" EXACT [] xref: PMID:18366659 "DDANAT:0000002" is_a: DDPHENO:0000236 ! aberrant cell morphogenesis [Term] id: DDPHENO:0000407 name: obsolete decreased chemoattractant-mediated F-actin polymerization def: "OBSOLETE. Reduction in extent, amount or degree of chemoattractant-mediated F-actin polymerization." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000408 name: increased resistance to carboplatin def: "Increase in extent, amount, or degree of tolerance to carboplatin." [DDB:pf] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus [Term] id: DDPHENO:0000409 name: decreased resistance to carboplatin def: "Decreased tolerance of the normal, usual, or expected events towards carboplatin." [DDB:pf] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus [Term] id: DDPHENO:0000410 name: decreased resistance to cisplatin def: "Decreased tolerance of the normal, usual, or expected events towards cisplatin." [DDB:pf] is_a: DDPHENO:0001456 ! aberrant response to cisplatin [Term] id: DDPHENO:0000411 name: increased cellular thermotolerance def: "Increased tolerance of the normal, usual, or expected events towards heat." [DDB:pf] synonym: "increased cellular heat acclimation" EXACT [] synonym: "increased resistance to heat shock" NARROW [] is_a: DDPHENO:0001035 ! aberrant cellular response to heat [Term] id: DDPHENO:0000412 name: aberrant cell-cell adhesion def: "Deviation from the normal, usual, or expected events during cell-cell adhesion." [DDB:pg] is_a: DDPHENO:0001044 ! aberrant cell adhesion [Term] id: DDPHENO:0000413 name: aberrant microtubule cytoskeleton organization def: "Deviation from the normal, usual, or expected events during organization of the microtubule cytoskeleton." [DDB:pg] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0000414 name: decreased cellular thermotolerance def: "Decreased tolerance of the normal, usual, or expected events towards heat." [DDB:pf] synonym: "decreased cellular heat acclimation" EXACT [] synonym: "decreased resistance to heat shock" NARROW [] is_a: DDPHENO:0001035 ! aberrant cellular response to heat [Term] id: DDPHENO:0000415 name: obsolete mislocalized prespore gene expression def: "OBSOLETE. Prespore gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2017-03-23T15:55:17Z [Term] id: DDPHENO:0000420 name: obsolete decreased cAMP-induced Ca2+ influx def: "OBSOLETE. Reduction in extent, amount or degree of cAMP-induced Ca2+ influx." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000421 name: obsolete delayed cAMP-induced Ca2+ influx def: "OBSOLETE. Late onset or slower progression for cAMP-induced Ca2+ influx." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000422 name: obsolete decreased Ca2+-induced Ca2+ influx def: "OBSOLETE. Reduction in extent, amount or degree of Ca2+ induced Ca2+ influx." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000423 name: obsolete decreased infection rate by Legionella pneumophila def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000424 name: abolished sporulation def: "Complete inability for sporulation." [DDB:pg] synonym: "abolished asexual sporulation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000425 name: decreased resistance to hydrogen peroxide def: "Reduction in extent, amount, or degree of the resistance to hydrogen peroxide." [DDB:pf] synonym: "decreased resistance to H2O2" EXACT [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0000426 name: aberrant response to UV def: "Deviation from the normal, usual, or expected events during the response to UV light." [DDB:pf] synonym: "aberrant response to UV light" EXACT [] is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0000427 name: obsolete decreased resistance to mitomycin C def: "OBSOLETE Decreased tolerance of the normal, usual, or expected events towards mitomycin C (MMC)." [DDB:pf] synonym: "decreased resistance to MMC" EXACT [] is_obsolete: true [Term] id: DDPHENO:0000428 name: decreased fatty acid level def: "Reduction in extent, amount or accumulation of fatty acid." [DDB:pg] synonym: "decreased fatty acid accumulation" RELATED [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000429 name: aberrant vesicle coat assembly def: "Deviation from the normal, usual, or expected process of vesicle coat assembly." [DDB:pg] synonym: "aberrant vesicle coating" EXACT [] is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0000430 name: decreased pinocytosis def: "Reduction in extent, amount, or degree of pinocytosis." [DDD:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000431 name: mitotic G1 phase arrest def: "The G1 phase in the mitotic cell cycle cannot complete." [DDB:pf] synonym: "G1 phase mitotic cell cycle arrest" EXACT [] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0000432 name: aberrant glycogen metabolism def: "Deviation from the normal, usual, or expected events during glycogen metabolism." [DDB:pg] synonym: "aberrant glycogen metabolic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000433 name: increased secretion of lysosomal enzymes def: "Increase in extent, amount, or degree of secretion of lysosomal enzymes." [DDB:pf] is_a: DDPHENO:0001232 ! increased protein secretion [Term] id: DDPHENO:0000434 name: aberrant pinosome maturation def: "Deviation from the normal, usual, or expected events during pinosome maturation." [DDB:pf] synonym: "aberrant pinosome assembly" EXACT [] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000437 name: decreased actin nucleation def: "Reduction in extent, amount, or degree of actin nucleation." [DDB:pg] synonym: "decreased actin nucleation on plasma membranes" NARROW [] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0000438 name: abolished uracil biosynthetic process def: "Complete inability to produce uracil." [DDB:pf] synonym: "uracil auxotroph" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0000439 name: increased resistance to 5-Fluoroorotic acid def: "Increase in extent, amount, or degree of resistance to 5-Fluoroorotic acid." [DDB:pf] synonym: "increased resistance to 5-FOA" EXACT [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0000440 name: abolished thymidine biosynthetic process def: "Complete inability to produce thymidine." [DDB:pf] synonym: "thymidine auxotroph" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0000441 name: obsolete increased extracellular of CF50 level def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000442 name: obsolete increased extracellular counting factor component(s) level def: "OBSOLETE. Increase in extent, amount, or degree of counting factr component level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000443 name: decreased secretion of lysosomal enzymes def: "Reduction in extent, amount, or degree of secretion of lysosomal enzymes." [DDB:pf] is_a: DDPHENO:0001233 ! decreased protein secretion [Term] id: DDPHENO:0000444 name: obsolete increased intracellular counting factor component(s) level def: "OBSOLETE. Increase in extent, amount, or degree of intracellular counting factor (CF) level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000445 name: increased slug migration def: "Increase in extent, amount, or degree of migration of slugs." [DDB:pg] synonym: "increased migratory slug locomotion" EXACT [] synonym: "slugger" NARROW [] is_a: DDPHENO:0001077 ! aberrant slug migration [Term] id: DDPHENO:0000446 name: aberrant mound color def: "Deviation from the normal, usual, or expected mound color." [DDB:pg] synonym: "aberrant aggregate color" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000447 name: obsolete increased myosin protein level def: "OBSOLETE. Increase in extent, amount, or degree of myosin protein level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000448 name: increased pinocytosis def: "Increase in extent, amount, or degree of pinocytosis." [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000449 name: obsolete no synthetic interaction def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000450 name: decreased number of mounds def: "Quantitative reduction in mounds." [DDB:pg] synonym: "decreased number of aggregates" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000451 name: obsolete increased number of peripheral cells during sexual reproduction def: "OBSOLETE. Quantitative increase in peripheral cells during sexual reproduction." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000452 name: decreased macrocyst size def: "Reduction in extent, amount, or degree of macrocysts size." [DDB:pf] synonym: "small macrocysts" EXACT [] is_a: DDPHENO:0001010 ! aberrant macrocyst formation [Term] id: DDPHENO:0000453 name: abolished protein localization to nucleus alt_id: DDPHENO:0000084 def: "Complete inability to localize a protein to the nucleus." [DDB:pf, DDB:pg] synonym: "abolished localization to nucleus" BROAD [] synonym: "abolished nuclear protein localization" EXACT [] is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0000454 name: decreased cGMP biosynthesis def: "Reduction in extent, amount, or degree of cGMP biosynthesis." [DDB:pf] synonym: "decreased accumulation of cGMP" RELATED [] synonym: "decreased cGMP biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000455 name: increased cGMP biosynthesis def: "Increase in extent, amount, or degree of cGMP biosynthesis." [DDB:pf] synonym: "increased accumulation of cGMP" RELATED [] synonym: "increased cGMP biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000456 name: obsolete increased actin phosphorylation def: "OBSOLETE. Increase in amount or accumulation of actin phosphorylation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000457 name: obsolete aberrant actin phosphorylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during actin phosphorylation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000459 name: increased actin filament polymerization def: "Increase in extent, amount, or degree of F-actin polymerization." [DDB:pg] synonym: "increased F-actin polymerization" EXACT [] is_a: DDPHENO:0001445 ! aberrant actin filament polymerization [Term] id: DDPHENO:0000461 name: decreased regulation of intracellular pH def: "Reduction of intracellular pH." [DDB:pf] synonym: "decreased cytosolic pH level" EXACT [] synonym: "intracellular pH reduction" EXACT [] synonym: "reduction of cellular pH" EXACT [] is_a: DDPHENO:0001455 ! aberrant regulation of intracellular pH [Term] id: DDPHENO:0000462 name: decreased filopodium formation def: "Reduction in extent, amount, or degree of filopodium formation." [DDB:pg] synonym: "decreased filopodium assembly" EXACT [] is_a: DDPHENO:0001028 ! aberrant filopodium formation [Term] id: DDPHENO:0000463 name: precocious prespore gene expression def: "Early onset or faster progression of prespore cell specific gene expression." [DDB:pf] synonym: "precocious prespore cell specific gene expression" EXACT [] is_a: DDPHENO:0000370 ! aberrant prespore gene expression is_a: DDPHENO:0001116 ! precocious gene expression created_by: pfey creation_date: 2017-03-23T15:57:06Z [Term] id: DDPHENO:0000464 name: aberrant protein localization to contractile vacuole def: "Deviation from the normal, usual, or expected during localization of a protein to contractile vacuole." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2017-04-20T17:03:31Z [Term] id: DDPHENO:0000465 name: obsolete abolished cAMP-induced Ca2+ influx def: "OBSOLETE. Complete inability for cAMP-induced Ca2+ influx." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000466 name: abolished positive chemotaxis def: "Complete inability for chemotaxis." [DDB:pg] is_a: DDPHENO:0001131 ! abolished taxis is_a: DDPHENO:0001224 ! aberrant positive chemotaxis [Term] id: DDPHENO:0000471 name: aberrant protein localization def: "Deviation from the normal, usual, or expected localization of a protein." [DDB:pf, DDB:pg] comment: Use for the altered localization of a protein that is affected by the mutation of another gene product. is_a: DDPHENO:0001217 ! aberrant cellular localization [Term] id: DDPHENO:0000472 name: aberrant regulation of protein modification def: "Deviation from the normal, usual, or expected events during the regulation of protein modification." [DDB:pg] synonym: "aberrant regulation of protein modification process" EXACT [] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0000473 name: increased establishment of cell polarity def: "Increase in extent, amount, or degree of cell polarity establishment." [DDB:pg] synonym: "increased cell polarity" EXACT [] is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity [Term] id: DDPHENO:0000474 name: decreased lateral pseudopodium formation def: "Reduction in extent, amount, or degree of formation of lateral pseudopodia." [DDB:pg] synonym: "decreased lateral pseudopodium assembly" EXACT [] is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation [Term] id: DDPHENO:0000475 name: increased resistance to alendronic acid def: "Increase in extent, amount, or degree of resistance to the drug alendronic acid." [DDB:pf] synonym: "increased resistance to alendronate" EXACT [] synonym: "increased resistance to bisphosphonate" RELATED [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0000477 name: aberrant lateral pseudopodium formation def: "Deviation from the normal, usual, or expected events during lateral pseudopodium formation." [DDB:pf] synonym: "aberrant lateral pseudopodium assembly" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0000478 name: increased lateral pseudopodium formation def: "Increase in extent, amount, or degree of formation of lateral pseudopods." [DDB:pg] synonym: "increased lateral pseudopodium assembly" EXACT [] is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation [Term] id: DDPHENO:0000479 name: obsolete decreased resistance to DNA-damaging agents def: "OBSOLETE. Decreased tolerance of the normal, usual, or expected events in the presence of DNA damaging agents." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000480 name: obsolete aberrant cAMP signaling def: "OBSOLETE. Deviation from the normal, usual, or expected events during cAMP signaling." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000481 name: obsolete decreased actin phosphorylation def: "OBSOLETE. Reduction in extent, amount, or degree of actin phosphorylation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000482 name: aberrant stream development def: "Deviation from the normal, usual, or expected process of streaming." [DDB:pg] synonym: "aberrant stream development during sorocarp development" EXACT [] synonym: "aberrant stream morphology" EXACT [] synonym: "aberrant streaming" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0000483 name: aberrant aggregation alt_id: DDPHENO:0000013 alt_id: DDPHENO:0000539 alt_id: DDPHENO:0000541 def: "Deviation from the normal, usual, or expected events during aggregation." [DDB:pg] synonym: "aberrant aggregation involved in sorocarp development" EXACT [] synonym: "merged_aberrant formation of the aggregation territory" RELATED [] synonym: "merged_aggregation defective" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0000484 name: obsolete curly fingers def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0000486 name: increased resistance to spectinomycin def: "Increase in extent, amount, or degree of resistance to the antibiotic spectinomycin." [DDB:pf] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0000487 name: abolished cell migration to prestalk region def: "Complete inability for cells to migrate to the prestalk region during the slug stage." [DDB:pg] synonym: "abolished sorting to prestalk region" EXACT [] is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region [Term] id: DDPHENO:0000488 name: delayed response to cAMP def: "Late onset or slower progression in the response to cAMP." [DDB:pg] is_a: DDPHENO:0000358 ! aberrant response to cAMP [Term] id: DDPHENO:0000489 name: obsolete increased cytosolic Ca2+ response def: "OBSOLETE. Increase in extent, amount, or degree of cytosolic Ca2+ response." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000490 name: decreased calcium ion import def: "Reduction in extent, amount, or degree of uptake of extracellular calcium." [DDB:pg] synonym: "decreased extracellular Ca2+ uptake" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0000491 name: abolished defence response to bacterium def: "Complete inability for a defence response to a bacterium." [DDB:pf] is_a: DDPHENO:0000258 ! aberrant defence response to bacterium [Term] id: DDPHENO:0000492 name: abolished stream development def: "Complete inability for streaming during early development." [DDB:pf] synonym: "abolished development of streams" EXACT [] synonym: "abolished stream development during sorocarp development" EXACT [] synonym: "abolished streaming" EXACT [] is_a: DDPHENO:0000482 ! aberrant stream development [Term] id: DDPHENO:0000493 name: obsolete abolished CRAC localization to the plasma membrane def: "OBSOLETE. Complete inability for CRAC localization to the plasma membrane." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000494 name: obsolete aberrant adaptation of adenylate cyclase def: "OBSOLETE. Deviation from the normal, usual, or expected events during the adaptation of adenylate cyclase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000495 name: obsolete decreased DNA methylation on cytosine def: "OBSOLETE. Reduction in extent, amount, or degree of cytosine methylation in genomic DNA." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000497 name: decreased number of vacuoles def: "Quantitative reduction in vacuoles." [DDB:pg] is_a: DDPHENO:0001041 ! aberrant vacuole organization [Term] id: DDPHENO:0000498 name: abolished autophagosome organizationn def: "Complete inability to form autophagic vacuoles." [DDB:pg] synonym: "abolished autophagic vacuole formation" EXACT [] is_a: DDPHENO:0000684 ! abolished vacuole organization [Term] id: DDPHENO:0000499 name: abolished cell-substrate adhesion def: "Complete inability for cell-substrate adhesion." [DDB:pg] synonym: "abolished substrate adhesion" RELATED [] is_a: DDPHENO:0000187 ! aberrant cell-substrate adhesion [Term] id: DDPHENO:0000500 name: decreased pinosome size def: "Decreased size of pinosomes." [DDB:pf] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000501 name: increased number of pinosomes def: "Quantitative increase in pinosomes." [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000503 name: precocious culmination def: "Early onset or faster progression through culmination." [DDB:pg] synonym: "precocious culmination involved in sorocarp development" EXACT [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000504 name: decreased sporulation alt_id: DDPHENO:0000194 def: "Reduction in extent, amount, or degree of spore formation." [DDB:pf] synonym: "decreased asexual sporulation" EXACT [] synonym: "decreased number of spores" RELATED [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0000509 name: obsolete delayed development in the presence of TMB-8 def: "OBSOLETE. Late onset or slower progression for development in the oresence of TMB-8." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000510 name: aberrant stalk morphology def: "Deviation from the normal, usual, or expected events during stalk morphogenesis." [DDB:pg] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000512 name: abolished prestalk cell differentiation def: "Complete inability for differentiation of prestalk cells." [DDB:pg] synonym: "abolished pst cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation is_a: DDPHENO:0001176 ! abolished cell differentiation [Term] id: DDPHENO:0000513 name: aberrant sporulation alt_id: DDPHENO:0000023 def: "Deviation from the normal, usual, or expected events during spore formation." [DDB:pf] synonym: "aberrant asexual sporulation" EXACT [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0000514 name: abolished stalk cell differentiation def: "Complete inability for differentiation into stalk cells." [DDB:pg] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation is_a: DDPHENO:0001176 ! abolished cell differentiation [Term] id: DDPHENO:0000516 name: abolished prespore cell differentiation def: "Complete inability for differentiation of prespore cells." [DDB:pg] is_a: DDPHENO:0001025 ! aberrant prespore cell differentiation is_a: DDPHENO:0001176 ! abolished cell differentiation [Term] id: DDPHENO:0000517 name: abolished protein localization to contractile vacuole def: "Complete inability to localize a protein to the contractile vacuole." [DDB:pf] is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2017-04-20T17:07:45Z [Term] id: DDPHENO:0000518 name: increased stalk width def: "Having a relative thick stalk." [DDB:pg] synonym: "thick stalk" EXACT [] xref: PATO:0000599 is_a: DDPHENO:0000510 ! aberrant stalk morphology [Term] id: DDPHENO:0000519 name: aberrant protein localization to contractile vacuole membrane def: "Deviation from the normal, usual, or expected during localization of a protein to the contractile vacuole membrane." [DDB:pf] synonym: "aberrant protein localization to contractile vacuolar membrane" EXACT [] is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole created_by: pfey creation_date: 2017-04-20T17:11:27Z [Term] id: DDPHENO:0000520 name: obsolete abolished stalk cell differentiation in vitro def: "OBSOLETE. Complete inability for differentiation into stalk cells in vitro." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000521 name: abolished protein localization to contractile vacuole membrane def: "Complete inability to localize a protein to the contractile vacuole membrane." [DDB:pf] synonym: "abolished localization to contractile vacuolar membrane" EXACT [] is_a: DDPHENO:0000517 ! abolished protein localization to contractile vacuole is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane created_by: pfey creation_date: 2017-04-20T17:14:01Z [Term] id: DDPHENO:0000522 name: decreased chemotaxis to cAMP def: "Reduction in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pg] synonym: "" RELATED [] synonym: "decreased positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000099 ! decreased chemotaxis rate is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0000523 name: decreased chemotaxis to folate def: "Reduction in extent, amount, or degree of chemotaxis in response to folate." [DDB:pg] synonym: "decreased chemotaxis to folic acid" EXACT [] synonym: "decreased positive chemotaxis to folate" EXACT [] synonym: "decreased positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000099 ! decreased chemotaxis rate is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0000524 name: increased cell migration to prestalk region def: "Increase in extent, amount, or degree of cell migration to the prestalk region during the slug stage." [DDB:pg] synonym: "increased sorting to prestalk region" EXACT [] is_a: DDPHENO:0000306 ! aberrant cell migration to prestalk region [Term] id: DDPHENO:0000525 name: delayed mitotic cell cycle def: "Increase in relative or proportionate duration of the mitotic cell cycle." [DDB:pf] synonym: "increased mitotic cell cycle duration" EXACT [] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0000526 name: obsolete increased prestalk cell differentiation in response to DIF-1 def: "OBSOLETE Increase in extent, amount, or degree of prestalk differentiation factor." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000527 name: obsolete abolished histone H3-K4 methylation def: "OBSOLETE Complete inability for methylation of histone H3 at lysine 4." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0000528 name: increased rate of endocytosis def: "Increase in extent, amount, or degree of endocytosis." [DDB:pf] is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0000529 name: increased stalk cell differentiation def: "Increase in extent, amount, or degree of differentiation into stalk cells." [DDB:pgg] synonym: "increased number of stalk cells" RELATED [] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation is_a: DDPHENO:0001174 ! increased cell differentiation [Term] id: DDPHENO:0000530 name: increased co-transcriptional gene silencing by RNA interference machinery def: "Increase in extent, amount, or degree of co-transciptional gene silencing by RNA." [DDB:pf] synonym: "increased small RNA-mediated cotranscriptional gene silencing" EXACT [] is_a: DDPHENO:0000008 ! aberrant co-transcriptional gene silencing by RNA interference machinery [Term] id: DDPHENO:0000531 name: increased contractile vacuole size def: "Increase in relative or proportionate dimensions of the contractile vacuole." [DDB:pf] is_a: DDPHENO:0001066 ! aberrant contractile vacuole morphology created_by: pfey creation_date: 2017-04-20T17:56:20Z [Term] id: DDPHENO:0000532 name: increased number of contractile vacuoles def: "Quantitative increase in contractile vacuoles." [DDB:pf] is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization created_by: pfey creation_date: 2017-04-20T18:02:17Z [Term] id: DDPHENO:0000533 name: aberrant mitotic anaphase def: "Deviation from the normal, usual, or expected events during mitotic anaphase." [DDB:pf] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0000535 name: decreased glycogen level def: "Reduction in amount or accumulation of intracellular glycogen." [DDB:pg] synonym: "decreased cytosolic glycogen level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000536 name: increased glutamate level def: "Increase in amount or accumulation of intracellular glutamate." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000537 name: increased ammonia level alt_id: DDPHENO:0001380 def: "Increase in amount or accumulation of ammonia." [DDB:pf] synonym: "increased extracellular ammonia level" NARROW [] synonym: "increased intracellular ammonia level" NARROW [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000538 name: decreased pteridine level def: "Reduction in amount or accumulation of intracellular pteridine." [DDB:pg] synonym: "decreased cytosolic pteridine level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0000540 name: increased pseudopodium size def: "Increase in relative or proportionate dimensions of the pseudopodium." [DDB:pg] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0000542 name: obsolete increased infection rate by Legionella pneumophila def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0000543 name: obsolete increased infection rate by Mycobacterium avium def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf] synonym: "increased sensitivity to infection by Mycobacterium avium" RELATED [] is_obsolete: true [Term] id: DDPHENO:0000544 name: abolished iron ion transport def: "Complete inability to transport iron." [DDB:pg] is_a: DDPHENO:0001026 ! aberrant ion transport [Term] id: DDPHENO:0000545 name: increased iron ion transport def: "Increase in extent, amount, or degree of transport of iron." [DDB:pg] is_a: DDPHENO:0001026 ! aberrant ion transport [Term] id: DDPHENO:0000546 name: aberrant stalk cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of stalk cells." [DDB:pg] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0000547 name: aberrant late culminant morphology def: "Deviation from the normal, usual, or expected morphogenesis of the late culminant." [DDB:pf] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0000549 name: decreased stalk width def: "Having a relative thin stalk." [DDB:pg] synonym: "thin stalk" EXACT [] xref: PATO:0000600 is_a: DDPHENO:0000510 ! aberrant stalk morphology [Term] id: DDPHENO:0000550 name: abolished pinocytosis def: "Complete inability to perform phagocytosis." [DDB:pg] is_a: DDPHENO:0001007 ! aberrant pinocytosis [Term] id: DDPHENO:0000551 name: increased pseudopodium formation def: "Increase in extent, amount, or degree of formation of pseudopodia." [DDB:pg] synonym: "increased pseudopod extension" RELATED [] synonym: "increased pseudopodium assembly" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0000552 name: abolished contractile vacuole organization def: "Complete inability to form a functional contractile vacuole." [DDB:pf] synonym: "abolished contractile vacuole formation" EXACT [] is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization is_a: DDPHENO:0000684 ! abolished vacuole organization created_by: pfey creation_date: 2017-04-20T18:05:43Z [Term] id: DDPHENO:0000553 name: aberrant contractile vacuole localization def: "Deviation from the normal, usual, or expected contractile vacuole localization." [DDB:pf] is_a: DDPHENO:0001218 ! aberrant organelle localization created_by: pfey creation_date: 2017-04-20T18:12:09Z [Term] id: DDPHENO:0000554 name: aberrant contractile vacuole tethering involved in discharge def: "Deviation from the normal, usual, or expected events during contractile vacuole attachment to the plasma membrane involved in discharge." [DDB:pf] synonym: "aberrant contractile vacuole tethering to plasma membrane" NARROW [] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2017-05-04T10:54:14Z [Term] id: DDPHENO:0000555 name: abolished contractile vacuole tethering involved in discharge def: "Complete inability for contractile vacuole tethering involved in discharge." [DDB:pf] synonym: "abolished contractile vacuole tethering to plasma membrane" RELATED [] is_a: DDPHENO:0000554 ! aberrant contractile vacuole tethering involved in discharge created_by: pfey creation_date: 2017-05-04T12:28:53Z [Term] id: DDPHENO:0000556 name: aberrant contractile vacuole dissociation from plasma membrane def: "Deviation from the normal, usual, or expected events during contractile vacuole dissociation from plasma membrane after discharge." [DDB:pf] synonym: "aberrant contractile vacuole detethering from plasma membrane" RELATED [] is_a: DDPHENO:0001047 ! aberrant transport created_by: pfey creation_date: 2017-05-04T12:44:12Z [Term] id: DDPHENO:0000557 name: abolished contractile vacuole dissociation from plasma membrane def: "Complete inability of contractile vacuole dissociation from plasma membrane after discharge." [DDB:pf] synonym: "abolished contractile vacuole detethering from plasma membrane" RELATED [] is_a: DDPHENO:0000556 ! aberrant contractile vacuole dissociation from plasma membrane created_by: pfey creation_date: 2017-05-04T12:44:52Z [Term] id: DDPHENO:0000558 name: aberrant pore formation during contractile vacuole discharge def: "Deviation from the normal, usual, or expected events during pore formation, part of contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2017-05-16T16:22:59Z [Term] id: DDPHENO:0000559 name: abolished pore formation during contractile vacuole discharge def: "Complete inability for pore formation, part of contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000558 ! aberrant pore formation during contractile vacuole discharge created_by: pfey creation_date: 2017-05-16T16:23:33Z [Term] id: DDPHENO:0000560 name: aberrant endosomal vesicle fusion def: "Deviation from the normal, usual, or expected events during homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf] synonym: "aberrant endosome fusion" EXACT [] synonym: "aberrant phagocytic vesicle fusion" NARROW [] synonym: "aberrant phagosome fusion" NARROW [] is_a: DDPHENO:0000090 ! aberrant endocytosis created_by: pfey creation_date: 2017-06-12T17:03:48Z [Term] id: DDPHENO:0000561 name: decreased endosomal vesicle fusion def: "Reduction in extent, amount, or degree of homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf] synonym: "decreased endosome fusion" EXACT [] synonym: "decreased phagocytic vesicle fusion" NARROW [] synonym: "decreased phagosome fusion" NARROW [] is_a: DDPHENO:0000560 ! aberrant endosomal vesicle fusion created_by: pfey creation_date: 2017-06-12T17:04:12Z [Term] id: DDPHENO:0000562 name: increased endosomal vesicle fusion def: "Increase in extent, amount, or degree of homotypic fusion of endocytic vesicles to form or add to an early endosome." [DDB:pf] synonym: "increased endosome fusion" EXACT [] synonym: "increased phagocytic vesicle fusion" NARROW [] synonym: "increased phagosome fusion" NARROW [] is_a: DDPHENO:0000560 ! aberrant endosomal vesicle fusion created_by: pfey creation_date: 2017-06-12T17:04:27Z [Term] id: DDPHENO:0000563 name: aberrant endoplasmic reticulum organization def: "Deviation from the normal, usual, or expected events during endoplasmic reticulum organization." [DDB:pf] synonym: "aberrant ER organization" EXACT [] is_a: DDPHENO:0001043 ! aberrant organelle organization created_by: pfey creation_date: 2017-08-10T12:20:08Z [Term] id: DDPHENO:0000564 name: aberrant endoplasmic reticulum membrane organization def: "Deviation from the normal, usual, or expected events during endoplasmic reticulum membrane organization." [DDB:pf] synonym: "aberrant ER membrane organization" EXACT [] is_a: DDPHENO:0000563 ! aberrant endoplasmic reticulum organization created_by: pfey creation_date: 2017-08-10T12:22:33Z [Term] id: DDPHENO:0000565 name: obsolete increased endoplasmic reticulum membrane accumulation def: "OBSOLETE. Quantitative increase in endoplasmic reticulum membrane accumulation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2017-08-10T12:24:55Z [Term] id: DDPHENO:0000566 name: aberrant lipid storage def: "Deviation from the normal, usual, or expected storage of lipids." [DDB:pf] is_a: DDPHENO:0001217 ! aberrant cellular localization created_by: pfey creation_date: 2017-10-24T11:44:39Z [Term] id: DDPHENO:0000567 name: aberrant lipid droplet formation def: "Deviation from the normal, usual, or expected formation of lipid droplets." [DDB:pf] is_a: DDPHENO:0000566 ! aberrant lipid storage created_by: pfey creation_date: 2017-10-24T11:46:08Z [Term] id: DDPHENO:0000568 name: decreased lipid droplet formation def: "Reduction in amount or accumulation of lipid droplets." [DDB:pf] is_a: DDPHENO:0000567 ! aberrant lipid droplet formation created_by: pfey creation_date: 2017-10-24T11:48:06Z [Term] id: DDPHENO:0000569 name: increased lipid droplet formation def: "Increase in amount or accumulation of lipid droplets." [DDB:pf] is_a: DDPHENO:0000567 ! aberrant lipid droplet formation created_by: pfey creation_date: 2017-10-24T11:50:05Z [Term] id: DDPHENO:0000570 name: abolished lipid droplet formation def: "Complete inability to form lipid droplets." [DDB:pf] is_a: DDPHENO:0000567 ! aberrant lipid droplet formation created_by: pfey creation_date: 2017-10-24T11:51:58Z [Term] id: DDPHENO:0000571 name: aberrant double-strand break repair via homologous recombination def: "Deviation from the normal, usual, or expected events during double-strand break repair of DNA via homologous recombination." [DDB:pf] synonym: "aberrant double-strand break repair via HR" EXACT [] synonym: "aberrant DSB repair via homologous recombination" EXACT [] is_a: DDPHENO:0000244 ! aberrant double-strand break repair created_by: pfey creation_date: 2017-11-30T15:45:59Z [Term] id: DDPHENO:0000572 name: decreased double-strand break repair via homologous recombination def: "Reduction in extent, amount, or degree of double strand break repair of DNA via homologous recombination." [DDB:pf] synonym: "decreased double-strand break repair via HR" EXACT [] synonym: "decreased DSB repair via homologous recombination" EXACT [] is_a: DDPHENO:0000245 ! decreased double-strand break repair is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination created_by: pfey creation_date: 2017-11-30T15:47:40Z [Term] id: DDPHENO:0000573 name: abolished double-strand break repair via homologous recombination def: "Complete inability for double strand break repair of DNA via homologous recombination." [DDB:pf] synonym: "abolished double-strand break repair via HR" EXACT [] synonym: "abolished DSB repair via homologous recombination" EXACT [] is_a: DDPHENO:0000247 ! abolished double strand break repair is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination created_by: pfey creation_date: 2017-11-30T15:52:53Z [Term] id: DDPHENO:0000574 name: increased double-strand break repair via homologous recombination def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair of DNA via homologous recombination." [DDB:pf] synonym: "increased double-strand break repair via HR" EXACT [] synonym: "increased DSB repair via homologous recombination" EXACT [] is_a: DDPHENO:0000249 ! increased double-strand break repair is_a: DDPHENO:0000571 ! aberrant double-strand break repair via homologous recombination created_by: pfey creation_date: 2017-11-30T15:54:41Z [Term] id: DDPHENO:0000575 name: aberrant double-strand break repair via nonhomologous end joining def: "Deviation from the normal, usual, or expected events during double-strand break repair of DNA via nonhomologous end joining." [DDB:pf] synonym: "aberrant double-strand break repair via NHEJ" EXACT [] synonym: "aberrant DSB repair via nonhomologous end joining" EXACT [] is_a: DDPHENO:0000244 ! aberrant double-strand break repair created_by: pfey creation_date: 2017-11-30T16:25:26Z [Term] id: DDPHENO:0000576 name: abolished double-strand break repair via nonhomologous end joining def: "Complete inability for double strand break repair of DNA via nonhomologous end joining." [DDB:pf] synonym: "abolished double-strand break repair via NHEJ" EXACT [] synonym: "abolished DSB repair via nonhomologous end joining" EXACT [] is_a: DDPHENO:0000247 ! abolished double strand break repair is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining created_by: pfey creation_date: 2017-11-30T16:28:18Z [Term] id: DDPHENO:0000577 name: decreased double-strand break repair via nonhomologous end joining def: "Reduction in extent, amount, or degree of double strand break repair of DNA via nonhomologous end joining." [DDB:pf] synonym: "decreased double-strand break repair via NHEJ" EXACT [] synonym: "decreased DSB repair via nonhomologous end joining" EXACT [] is_a: DDPHENO:0000245 ! decreased double-strand break repair is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining created_by: pfey creation_date: 2017-11-30T16:33:41Z [Term] id: DDPHENO:0000578 name: increased double-strand break repair via nonhomologous end joining def: "Increased tolerance of the normal, usual, or expected events in double-strand break repair of DNA nonhomologous end joining." [DDB:pf] synonym: "increased double-strand break repair via NHEJ" EXACT [] synonym: "increased DSB repair via nonhomologous end joining" EXACT [] is_a: DDPHENO:0000249 ! increased double-strand break repair is_a: DDPHENO:0000575 ! aberrant double-strand break repair via nonhomologous end joining created_by: pfey creation_date: 2017-11-30T16:34:11Z [Term] id: DDPHENO:0000579 name: aberrant cheating during development def: "Deviation from the normal, usual, or expected sorting to prestalk region when mixed with cheater cells." [DDB:pf] synonym: "aberrant cheating during chimeric sorocarp development" EXACT [] is_a: DDPHENO:0000127 ! aberrant socially cooperative development created_by: pfey creation_date: 2018-01-31T15:28:37Z [Term] id: DDPHENO:0000580 name: increased resistance to cheating during development def: "Increase in extent, amount, or degree of resistance towards cheater cells compared to wild type." [DDB:pf] synonym: "increased resistance to cheating during chimeric sorocarp development" EXACT [] is_a: DDPHENO:0000579 ! aberrant cheating during development created_by: pfey creation_date: 2018-01-31T15:28:50Z [Term] id: DDPHENO:0000581 name: decreased resistance to cheating during development def: "Decreased tolerance of the normal, usual, or expected events towards cheater cells compared to wild type." [DDB:pf] synonym: "decreased resistance to cheating during chimeric sorocarp development" EXACT [] is_a: DDPHENO:0000579 ! aberrant cheating during development created_by: pfey creation_date: 2018-01-31T15:29:25Z [Term] id: DDPHENO:0000582 name: obsolete abolished response to cheating def: "OBSOLETE. Complete resistance to cheating when mixed with cheater cells." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2018-01-31T15:29:40Z [Term] id: DDPHENO:0000583 name: aberrant mating type determination def: "Deviation from the normal, usual, or expected events when determining the mating type of a cell." [DDB:pf] is_a: DDPHENO:0001443 ! aberrant cell fate determination created_by: pfey creation_date: 2019-03-01T15:50:16Z [Term] id: DDPHENO:0000584 name: abolished mating type determination def: "Complete inability for determining the mating type of a cell." [DDB:pf] is_a: DDPHENO:0000583 ! aberrant mating type determination created_by: pfey creation_date: 2019-03-01T15:53:27Z [Term] id: DDPHENO:0000585 name: aberrant cellular response to hypoxia def: "Deviation from the normal, usual, or expected events during the cellular response to lowered oxygen tension." [DDB:pf] comment: GO:0071456. synonym: "aberrant cellular response to decreased oxygen" EXACT [] is_a: DDPHENO:0001034 ! aberrant cellular response to stress created_by: pfey creation_date: 2019-11-18T14:20:30Z [Term] id: DDPHENO:0000586 name: decreased cellular response to hypoxia def: "Decreased cellular response to the normal, usual, or expected events in the presence of lower oxygen levels." [DDB:pf] synonym: "decreased cellular response to lowered oxygen levels" EXACT [] synonym: "decreased response to cellular hypoxic stress" EXACT [] is_a: DDPHENO:0000585 ! aberrant cellular response to hypoxia created_by: pfey creation_date: 2019-11-18T14:23:53Z [Term] id: DDPHENO:0000587 name: increased cellular response to hypoxia def: "Increased cellular response to the normal, usual, or expected events in the presence of lower oxygen levels." [DDB:pf] synonym: "increased cellular response to hypoxic stress" EXACT [] synonym: "increased cellular response to lowered oxygen levels" EXACT [] is_a: DDPHENO:0000585 ! aberrant cellular response to hypoxia created_by: pfey creation_date: 2019-11-18T14:28:11Z [Term] id: DDPHENO:0000588 name: decreased response to Gram-positive bacterium def: "Reduction in extent, amount, or degree of the response to Gram-positive bacterium as a food source." [DDB:pf] comment: Gram-positive bacteria (examples):\nB. subtilis\nS. aureus\nM. luteus. synonym: "decreased growth on Gram-positive bacteria" NARROW [] is_a: DDPHENO:0000594 ! decreased response to bacterium created_by: pfey creation_date: 2020-04-16T13:44:00Z [Term] id: DDPHENO:0000589 name: abolished response to Gram-positive bacterium def: "Complete inability for cells to respond to Gram-positive bacteria as a food source." [DDB:pf] comment: Gram-positive bacteria (examples):\nB. subtilis\nS. aureus\nM. luteus. synonym: "abolished growth on Gram-positive bacteria" NARROW [] is_a: DDPHENO:0000593 ! abolished response to bacterium created_by: pfey creation_date: 2020-04-16T13:48:45Z [Term] id: DDPHENO:0000590 name: decreased response to Gram-negative bacterium def: "Reduction in extent, amount, or degree of the response to Gram-negative bacterium as a food source." [DDB:pf] comment: Gram-negative bacteria (examples):\nK. pneumonia\nE. coli\nP. aeruginosa. synonym: "decreased growth on Gram-negative bacteria" NARROW [] is_a: DDPHENO:0000594 ! decreased response to bacterium created_by: pfey creation_date: 2020-04-16T13:51:28Z [Term] id: DDPHENO:0000591 name: abolished response to Gram-negative bacterium def: "Complete inability for a response to Gram-negative bacteria as a food source." [DDB:pf] comment: Gram-negative bacteria (examples):\nK. pneumonia\nE. coli\nP. aeruginosa. synonym: "abolished growth on Gram-negative bacteria" NARROW [] is_a: DDPHENO:0000593 ! abolished response to bacterium created_by: pfey creation_date: 2020-04-16T13:53:46Z [Term] id: DDPHENO:0000592 name: aberrant response to bacterium def: "Deviation from the normal, usual, or expected events during the response to bacteria." [DDB:pf] is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus created_by: pfey creation_date: 2020-05-04T13:08:38Z [Term] id: DDPHENO:0000593 name: abolished response to bacterium def: "Complete inability for a response to bacteria as a food source." [DDB:pf] is_a: DDPHENO:0000592 ! aberrant response to bacterium created_by: pfey creation_date: 2020-05-04T13:12:36Z [Term] id: DDPHENO:0000594 name: decreased response to bacterium def: "Reduction in extent, amount, or degree of the response to bacteria as a food source." [DDB:pf] is_a: DDPHENO:0000592 ! aberrant response to bacterium created_by: pfey creation_date: 2020-05-04T13:13:44Z [Term] id: DDPHENO:0000595 name: obsolete increased actin wave formation def: "OBSOLETE. Increase in extent, amount, or degree of typically cortical actin wave formation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2020-06-12T09:23:59Z [Term] id: DDPHENO:0000596 name: decreased spore stability def: "Reduction of the time span a spore is viable after sporulation." [DDB:pf] is_a: DDPHENO:0000513 ! aberrant sporulation created_by: pfey creation_date: 2020-06-12T13:55:27Z [Term] id: DDPHENO:0000597 name: precocious contractile vacuole discharge def: "Early onset or faster progression through contractile vacuole discharge." [DDB:pf] is_a: DDPHENO:0000034 ! aberrant contractile vacuole discharge created_by: pfey creation_date: 2020-07-06T13:55:30Z [Term] id: DDPHENO:0000598 name: decreased number of post-lysosomal vacuoles def: "Quantitative reduction of the post-lysosomal vacuole number." [DDB:pf] synonym: "decreased number of postlysosomes" EXACT [] is_a: DDPHENO:0001237 ! aberrant lysosome organization created_by: pfey creation_date: 2020-07-07T09:24:23Z [Term] id: DDPHENO:0000599 name: decreased post-lysosomal vacuole size def: "Decrease in relative or proportionate dimensions of the post-lysosomal vacuole." [DDB:pf] synonym: "decreased postlysosome size" EXACT [] is_a: DDPHENO:0001237 ! aberrant lysosome organization created_by: pfey creation_date: 2020-07-07T09:28:21Z [Term] id: DDPHENO:0000600 name: aberrant intermediate filament organization def: "Deviation from the normal, usual, or expected events during organization of intermediate filaments." [DDB:pf] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization created_by: pfey creation_date: 2020-08-13T10:08:45Z [Term] id: DDPHENO:0000601 name: aberrant intermediate filament bundle assembly def: "Deviation from the normal, usual, or expected events during intermediate filament bundle assembly." [DDB:pf] is_a: DDPHENO:0000600 ! aberrant intermediate filament organization created_by: pfey creation_date: 2020-08-13T10:10:37Z [Term] id: DDPHENO:0000602 name: increased intermediate filament bundle assembly def: "Quantitative increase in intermediate filament bundle assembly." [DDB:pf] is_a: DDPHENO:0000601 ! aberrant intermediate filament bundle assembly created_by: pfey creation_date: 2020-08-13T10:11:40Z [Term] id: DDPHENO:0000603 name: decreased intermediate filament bundle assembly def: "Reduction in extent, amount, or degree of intermediate filament bundle assembly." [DDB:pf] is_a: DDPHENO:0000601 ! aberrant intermediate filament bundle assembly created_by: pfey creation_date: 2020-08-13T10:17:12Z [Term] id: DDPHENO:0000604 name: aberrant protein localization to leading edge def: "Deviation from the normal, usual, or expected events during localization of a protein to the leading edge." [DDB:pf] synonym: "aberrant protein localization to cell leading edge" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T12:08:30Z [Term] id: DDPHENO:0000605 name: abolished protein localization to leading edge def: "Complete inability to localize a protein to the leading edge." [DDB:pf] synonym: "abolished protein localization to cell leading edge" EXACT [] is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:00:20Z [Term] id: DDPHENO:0000606 name: decreased protein localization to leading edge def: "Reduction in amount or accumulation of a protein to the leading edge." [DDB:pf] synonym: "decreased protein localization to cell leading edge" EXACT [] is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:02:06Z [Term] id: DDPHENO:0000607 name: increased protein localization to leading edge def: "Increase in amount or accumulation of a protein to the leading edge." [DDB:pf] synonym: "increased protein localization to cell leading edge" EXACT [] is_a: DDPHENO:0000604 ! aberrant protein localization to leading edge is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:08:59Z [Term] id: DDPHENO:0000608 name: aberrant protein localization to actin wave def: "Deviation from the normal, usual, or expected events during localization of a protein to the actin wave." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:11:40Z [Term] id: DDPHENO:0000609 name: abolished protein localization to actin wave def: "Complete inability to localize a protein to the actin wave." [DDB:pf] is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:13:07Z [Term] id: DDPHENO:0000610 name: decreased protein localization to actin wave def: "Reduction in amount or accumulation of a protein to the actin wave." [DDB:pf] is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:14:22Z [Term] id: DDPHENO:0000611 name: increased protein localization to actin wave def: "Increase in amount or accumulation of a protein to the actin wave." [DDB:pf] is_a: DDPHENO:0000608 ! aberrant protein localization to actin wave is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:15:31Z [Term] id: DDPHENO:0000612 name: aberrant protein localization to trailing edge def: "Deviation from the normal, usual, or expected events during localization of a protein to the trailing edge." [DDB:pf] synonym: "aberrant protein localization to cell trailing edge" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:16:55Z [Term] id: DDPHENO:0000613 name: abolished protein localization to trailing edge def: "Complete inability to localize a protein to the trailing edge." [DDB:pf] synonym: "abolished protein localization to cell trailing edge" EXACT [] is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:17:15Z [Term] id: DDPHENO:0000614 name: decreased protein localization to trailing edge def: "Reduction in amount or accumulation of a protein to the trailing edge." [DDB:pf] synonym: "decreased protein localization to cell trailing edge" EXACT [] is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:17:29Z [Term] id: DDPHENO:0000615 name: increased protein localization to trailing edge def: "Increase in amount or accumulation of a protein to the trailing edge." [DDB:pf] synonym: "increased protein localization to cell trailing edge" EXACT [] is_a: DDPHENO:0000612 ! aberrant protein localization to trailing edge is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:17:43Z [Term] id: DDPHENO:0000616 name: aberrant protein localization to filopodium def: "Deviation from the normal, usual, or expected events during localization of a protein to the filopodia." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:24:40Z [Term] id: DDPHENO:0000617 name: abolished protein localization to filopodium def: "Complete inability to localize a protein to the filopodia." [DDB:pf] is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:24:55Z [Term] id: DDPHENO:0000618 name: decreased protein localization to filopodium def: "Reduction in amount or accumulation of a protein to the filopodia." [DDB:pf] is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:25:12Z [Term] id: DDPHENO:0000619 name: increased protein localization to filopodium def: "Increase in amount or accumulation of a protein to the filopodia." [DDB:pf] is_a: DDPHENO:0000616 ! aberrant protein localization to filopodium is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:25:27Z [Term] id: DDPHENO:0000620 name: aberrant protein localization to phagocytic vesicle def: "Deviation from the normal, usual, or expected events during localization of a protein to the phagocytic vesicle." [DDB:pf] synonym: "aberrant protein localization to phagosome" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:34:19Z [Term] id: DDPHENO:0000621 name: abolished protein localization to phagocytic vesicle def: "Complete inability to localize a protein to the phagocytic vesicle." [DDB:pf] synonym: "abolished protein localization to phagosome" EXACT [] is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:34:52Z [Term] id: DDPHENO:0000622 name: decreased protein localization to phagocytic vesicle def: "Reduction in amount or accumulation of a protein to the phagocytic vesicle." [DDB:pf] synonym: "decreased protein localization to phagosome" EXACT [] is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:36:34Z [Term] id: DDPHENO:0000623 name: increased protein localization to phagocytic vesicle def: "Increase in amount or accumulation of a protein to the phagocytic vesicle." [DDB:pf] synonym: "increased protein localization to phagosome" EXACT [] is_a: DDPHENO:0000620 ! aberrant protein localization to phagocytic vesicle is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:36:52Z [Term] id: DDPHENO:0000624 name: aberrant protein localization to centrosome def: "Deviation from the normal, usual, or expected events during localization of a protein to the centrosome." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:48:38Z [Term] id: DDPHENO:0000625 name: abolished protein localization to centrosome def: "Complete inability to localize a protein to the centrosome." [DDB:pf] is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:48:55Z [Term] id: DDPHENO:0000626 name: decreased protein localization to centrosome def: "Reduction in amount or accumulation of a protein to the centrosome." [DDB:pf] is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome created_by: pfey creation_date: 2020-11-05T13:49:09Z [Term] id: DDPHENO:0000627 name: increased protein localization to centrosome def: "Increase in amount or accumulation of a protein to the centrosome." [DDB:pf] is_a: DDPHENO:0000624 ! aberrant protein localization to centrosome created_by: pfey creation_date: 2020-11-05T13:49:27Z [Term] id: DDPHENO:0000628 name: aberrant protein localization to macropinosome def: "Deviation from the normal, usual, or expected events during localization of a protein to the macropinosome." [DDB:pf] synonym: "aberrant protein localization to macropinocytic cup" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T13:54:49Z [Term] id: DDPHENO:0000629 name: abolished protein localization to macropinosome def: "Complete inability to localize a protein to the macropinosome." [DDB:pf] synonym: "abolished protein localization to macropinocytic cup" EXACT [] is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T13:55:37Z [Term] id: DDPHENO:0000630 name: decreased protein localization to macropinosome def: "Reduction in amount or accumulation of a protein to the macropinosome." [DDB:pf] synonym: "decreased protein localization to macropinocytic cup" EXACT [] is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T13:55:55Z [Term] id: DDPHENO:0000631 name: increased protein localization to macropinosome def: "Increase in amount or accumulation of a protein to the macropinosome." [DDB:pf] synonym: "increased protein localization to macropinocytic cup" EXACT [] is_a: DDPHENO:0000628 ! aberrant protein localization to macropinosome is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T13:56:18Z [Term] id: DDPHENO:0000632 name: aberrant protein localization to autophagosome def: "Deviation from the normal, usual, or expected events during localization of a protein to the autophagosome." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T14:18:27Z [Term] id: DDPHENO:0000633 name: abolished protein localization to autophagosome def: "Complete inability to localize a protein to the autophagosome." [DDB:pf] is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T14:18:46Z [Term] id: DDPHENO:0000634 name: decreased protein localization to autophagosome def: "Reduction in amount or accumulation of a protein to the autophagosome." [DDB:pf] is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T14:19:03Z [Term] id: DDPHENO:0000635 name: increased protein localization to autophagosome def: "Increase in amount or accumulation of a protein to the autophagosome." [DDB:pf] is_a: DDPHENO:0000632 ! aberrant protein localization to autophagosome is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T14:19:18Z [Term] id: DDPHENO:0000636 name: aberrant protein localization to cell-cell contact zone def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell-cell contact zone." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T14:29:12Z [Term] id: DDPHENO:0000637 name: abolished protein localization to cell-cell contact zone def: "Complete inability to localize a protein to the cell-cell contact zone." [DDB:pf] is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T14:29:33Z [Term] id: DDPHENO:0000638 name: decreased protein localization to cell-cell contact zone def: "Reduction in amount or accumulation of a protein to the cell-cell contact zone." [DDB:pf] is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T14:29:46Z [Term] id: DDPHENO:0000639 name: increased protein localization to cell-cell contact zone def: "Increase in amount or accumulation of a protein to the cell-cell contact zone." [DDB:pf] is_a: DDPHENO:0000636 ! aberrant protein localization to cell-cell contact zone is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T14:30:03Z [Term] id: DDPHENO:0000640 name: aberrant protein localization to basolateral plasma membrane def: "Deviation from the normal, usual, or expected events during localization of a protein to the basolateral plasma membrane." [DDB:pf] is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T16:35:48Z [Term] id: DDPHENO:0000641 name: abolished protein localization to basolateral plasma membrane def: "Complete inability to localize a protein to the basolateral plasma membrane." [DDB:pf] is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane is_a: DDPHENO:0001394 ! abolished protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T16:36:03Z [Term] id: DDPHENO:0000642 name: decreased protein localization to basolateral plasma membrane def: "Reduction in amount or accumulation of a protein to the basolateral plasma membrane." [DDB:pf] is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane is_a: DDPHENO:0001395 ! decreased protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T16:36:23Z [Term] id: DDPHENO:0000643 name: increased protein localization to basolateral plasma membrane def: "Increase in amount or accumulation of a protein to the basolateral plasma membrane." [DDB:pf] is_a: DDPHENO:0000640 ! aberrant protein localization to basolateral plasma membrane is_a: DDPHENO:0001396 ! increased protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T16:36:44Z [Term] id: DDPHENO:0000644 name: aberrant protein localization to cleavage furrow def: "Deviation from the normal, usual, or expected events during localization of a protein to the cleavage furrow." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T16:40:08Z [Term] id: DDPHENO:0000645 name: abolished protein localization to cleavage furrow def: "Complete inability to localize a protein to the cleavage furrow." [DDB:pf] is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T16:40:58Z [Term] id: DDPHENO:0000646 name: decreased protein localization to cleavage furrow def: "Reduction in amount or accumulation of a protein to the cleavage furrow." [DDB:pf] is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T16:41:13Z [Term] id: DDPHENO:0000647 name: increased protein localization to cleavage furrow def: "Increase in amount or accumulation of a protein to the cleavage furrow." [DDB:pf] is_a: DDPHENO:0000644 ! aberrant protein localization to cleavage furrow is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T16:41:27Z [Term] id: DDPHENO:0000648 name: aberrant protein localization to lysosome def: "Deviation from the normal, usual, or expected events during localization of a protein to the lysosome." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T16:45:10Z [Term] id: DDPHENO:0000649 name: abolished protein localization to lysosome def: "Complete inability to localize a protein to the lysosome." [DDB:pf] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T16:45:33Z [Term] id: DDPHENO:0000650 name: decreased protein localization to lysosome def: "Reduction in amount or accumulation of a protein to the lysosome." [DDB:pf] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome created_by: pfey creation_date: 2020-11-05T16:45:48Z [Term] id: DDPHENO:0000651 name: increased protein localization to lysosome def: "Increase in amount or accumulation of a protein to the lysosome." [DDB:pf] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome created_by: pfey creation_date: 2020-11-05T16:46:13Z [Term] id: DDPHENO:0000652 name: aberrant protein localization to post-lysosomal vacuole def: "Deviation from the normal, usual, or expected events during localization of a protein to the post-lysosomal vacuole." [DDB:pf] synonym: "aberrant protein localization to postlysosome" EXACT [] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome created_by: pfey creation_date: 2020-11-05T16:54:22Z [Term] id: DDPHENO:0000653 name: abolished protein localization to post-lysosomal vacuole def: "Complete inability to localize a protein to the post-lysosomal vacuole." [DDB:pf] synonym: "abolished protein localization to postlysosome" EXACT [] is_a: DDPHENO:0000649 ! abolished protein localization to lysosome is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole created_by: pfey creation_date: 2020-11-05T16:55:04Z [Term] id: DDPHENO:0000654 name: decreased protein localization to post-lysosomal vacuole def: "Reduction in amount or accumulation of a protein to the post-lysosomal vacuole." [DDB:pf] synonym: "decreased protein localization to postlysosome" EXACT [] is_a: DDPHENO:0000650 ! decreased protein localization to lysosome is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole created_by: pfey creation_date: 2020-11-05T16:55:33Z [Term] id: DDPHENO:0000655 name: increased protein localization to post-lysosomal vacuole def: "Increase in amount or accumulation of a protein to the post-lysosomal vacuole." [DDB:pf] synonym: "increased protein localization to postlysosome" EXACT [] is_a: DDPHENO:0000651 ! increased protein localization to lysosome is_a: DDPHENO:0000652 ! aberrant protein localization to post-lysosomal vacuole created_by: pfey creation_date: 2020-11-05T16:55:46Z [Term] id: DDPHENO:0000656 name: aberrant protein localization to lysosomal membrane def: "Deviation from the normal, usual, or expected events during localization of a protein to the lysosomal membrane." [DDB:pf] synonym: "aberrant protein localization to lysosome membrane" EXACT [] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome created_by: pfey creation_date: 2020-11-05T17:19:29Z [Term] id: DDPHENO:0000657 name: abolished protein localization to lysosomal membrane def: "Complete inability to localize a protein to the lysosomal membrane." [DDB:pf] synonym: "abolished protein localization to lysosome membrane" EXACT [] is_a: DDPHENO:0000649 ! abolished protein localization to lysosome is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane created_by: pfey creation_date: 2020-11-05T17:20:08Z [Term] id: DDPHENO:0000658 name: decreased protein localization to lysosomal membrane def: "Reduction in amount or accumulation of a protein to the lysosomal membrane." [DDB:pf] synonym: "decreased protein localization to lysosome membrane" EXACT [] is_a: DDPHENO:0000650 ! decreased protein localization to lysosome is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane created_by: pfey creation_date: 2020-11-05T17:20:24Z [Term] id: DDPHENO:0000659 name: increased protein localization to lysosomal membrane def: "Increase in amount or accumulation of a protein to the lysosomal membrane." [DDB:pf] synonym: "increased protein localization to lysosome membrane" EXACT [] is_a: DDPHENO:0000651 ! increased protein localization to lysosome is_a: DDPHENO:0000656 ! aberrant protein localization to lysosomal membrane created_by: pfey creation_date: 2020-11-05T17:20:37Z [Term] id: DDPHENO:0000660 name: aberrant protein localization to mitotic spindle def: "Deviation from the normal, usual, or expected events during localization of a protein to the mitotic spindle." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T17:27:51Z [Term] id: DDPHENO:0000661 name: abolished protein localization to mitotic spindle def: "Complete inability to localize a protein to the mitotic spindle." [DDB:pf] is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T17:28:10Z [Term] id: DDPHENO:0000662 name: decreased protein localization to mitotic spindle def: "Reduction in amount or accumulation of a protein to the mitotic spindle." [DDB:pf] is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T17:28:24Z [Term] id: DDPHENO:0000663 name: increased protein localization to mitotic spindle def: "Increase in amount or accumulation of a protein to the mitotic spindle." [DDB:pf] is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T17:28:53Z [Term] id: DDPHENO:0000664 name: aberrant protein localization to mitotic spindle midzone def: "Deviation from the normal, usual, or expected events during localization of a protein to the mitotic spindle midzone." [DDB:pf] is_a: DDPHENO:0000660 ! aberrant protein localization to mitotic spindle created_by: pfey creation_date: 2020-11-05T17:29:42Z [Term] id: DDPHENO:0000665 name: abolished protein localization to mitotic spindle midzone def: "Complete inability to localize a protein to the mitotic spindle midzone." [DDB:pf] is_a: DDPHENO:0000661 ! abolished protein localization to mitotic spindle is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone created_by: pfey creation_date: 2020-11-05T17:30:02Z [Term] id: DDPHENO:0000666 name: decreased protein localization to mitotic spindle midzone def: "Reduction in amount or accumulation of a protein to the mitotic spindle midzone." [DDB:pf] is_a: DDPHENO:0000662 ! decreased protein localization to mitotic spindle is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone created_by: pfey creation_date: 2020-11-05T17:30:16Z [Term] id: DDPHENO:0000667 name: increased protein localization to mitotic spindle midzone def: "Increase in amount or accumulation of a protein to the mitotic spindle midzone." [DDB:pf] is_a: DDPHENO:0000663 ! increased protein localization to mitotic spindle is_a: DDPHENO:0000664 ! aberrant protein localization to mitotic spindle midzone created_by: pfey creation_date: 2020-11-05T17:30:31Z [Term] id: DDPHENO:0000668 name: aberrant protein localization to cytoplasmic vesicle def: "Deviation from the normal, usual, or expected events during localization of a protein to the cytoplasmic vesicle." [DDB:pf] is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm created_by: pfey creation_date: 2020-11-05T17:43:09Z [Term] id: DDPHENO:0000669 name: abolished protein localization to cytoplasmic vesicle def: "Complete inability to localize a protein to the cytoplasmic vesicle." [DDB:pf] is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle is_a: DDPHENO:0001392 ! abolished protein localization to cytoplasm created_by: pfey creation_date: 2020-11-05T17:43:49Z [Term] id: DDPHENO:0000670 name: decreased protein localization to cytoplasmic vesicle def: "Reduction in amount or accumulation of a protein to the cytoplasmic vesicle." [DDB:pf] is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle is_a: DDPHENO:0001391 ! decreased protein localization to cytoplasm created_by: pfey creation_date: 2020-11-05T17:45:09Z [Term] id: DDPHENO:0000671 name: increased protein localization to cytoplasmic vesicle def: "Increase in amount or accumulation of a protein to the cytoplasmic vesicle." [DDB:pf] is_a: DDPHENO:0000668 ! aberrant protein localization to cytoplasmic vesicle is_a: DDPHENO:0001390 ! increased protein localization to cytoplasm created_by: pfey creation_date: 2020-11-05T17:45:22Z [Term] id: DDPHENO:0000672 name: aberrant protein localization to cell periphery def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell periphery." [DDB:pf] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2020-11-05T17:52:52Z [Term] id: DDPHENO:0000673 name: abolished protein localization to cell periphery def: "Complete inability to localize a protein to the cell periphery." [DDB:pf] is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery is_a: DDPHENO:0001393 ! abolished protein localization created_by: pfey creation_date: 2020-11-05T17:54:34Z [Term] id: DDPHENO:0000674 name: aberrant protein localization to apical plasma membrane def: "Deviation from the normal, usual, or expected events during localization of a protein from the cytoplasm to the apical plasma membrane." [DDB:pf] is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T18:14:57Z [Term] id: DDPHENO:0000675 name: abolished protein localization to apical plasma membrane def: "Complete inability to localize a protein to the apical plasma membrane." [DDB:pf] is_a: DDPHENO:0000674 ! aberrant protein localization to apical plasma membrane is_a: DDPHENO:0001394 ! abolished protein localization to plasma membrane created_by: pfey creation_date: 2020-11-05T18:15:44Z [Term] id: DDPHENO:0000676 name: aberrant protein localization to endolysosome def: "Deviation from the normal, usual, or expected events during localization of a protein to the endolysosome." [DDB:pf] is_a: DDPHENO:0000648 ! aberrant protein localization to lysosome created_by: pfey creation_date: 2020-11-05T18:26:02Z [Term] id: DDPHENO:0000677 name: abolished protein localization to endolysosome def: "Complete inability to localize a protein to the endolysosome." [DDB:pf] is_a: DDPHENO:0000649 ! abolished protein localization to lysosome is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome created_by: pfey creation_date: 2020-11-05T18:27:17Z [Term] id: DDPHENO:0000678 name: decreased protein localization to endolysosome def: "Reduction in amount or accumulation of a protein to the endolysosome." [DDB:pf] is_a: DDPHENO:0000650 ! decreased protein localization to lysosome is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome created_by: pfey creation_date: 2020-11-05T18:27:48Z [Term] id: DDPHENO:0000679 name: increased protein localization to endolysosome def: "Increase in amount or accumulation of a protein to the endolysosome." [DDB:pf] is_a: DDPHENO:0000651 ! increased protein localization to lysosome is_a: DDPHENO:0000676 ! aberrant protein localization to endolysosome created_by: pfey creation_date: 2020-11-05T18:28:02Z [Term] id: DDPHENO:0000680 name: decreased protein localization to contractile vacuole def: "Reduction in amount or accumulation of a protein to the contractile vacuole." [DDB:pf] is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole is_a: DDPHENO:0001338 ! decreased protein localization created_by: pfey creation_date: 2020-11-05T20:31:48Z [Term] id: DDPHENO:0000681 name: increased protein localization to contractile vacuole def: "Increase in amount or accumulation of a protein to the contractile vacuole." [DDB:pf] is_a: DDPHENO:0000464 ! aberrant protein localization to contractile vacuole is_a: DDPHENO:0001337 ! increased protein localization created_by: pfey creation_date: 2020-11-05T20:32:27Z [Term] id: DDPHENO:0000682 name: decreased protein localization to contractile vacuole membrane def: "Reduction in amount or accumulation of a protein to the contractile vacuole membrane." [DDB:pf] is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane is_a: DDPHENO:0000680 ! decreased protein localization to contractile vacuole created_by: pfey creation_date: 2020-11-05T20:35:24Z [Term] id: DDPHENO:0000683 name: increased protein localization to contractile vacuole membrane def: "Increase in amount or accumulation of a protein to the contractile vacuole membrane." [DDB:pf] is_a: DDPHENO:0000519 ! aberrant protein localization to contractile vacuole membrane is_a: DDPHENO:0000681 ! increased protein localization to contractile vacuole created_by: pfey creation_date: 2020-11-05T20:36:38Z [Term] id: DDPHENO:0000684 name: abolished vacuole organization def: "Complete inability to form a functional vacuole." [DDB:pf] synonym: "abolished vacuolar assembly" NARROW [] synonym: "abolished vacuolation" RELATED [] synonym: "abolished vacuole formation" EXACT [] is_a: DDPHENO:0001041 ! aberrant vacuole organization created_by: pfey creation_date: 2020-11-24T12:08:23Z [Term] id: DDPHENO:0000685 name: development arrests at standing slug stage def: "Development cannot progress past the standing slug stage." [DDB:pf] synonym: "development arrests at finger stage" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development created_by: pfey creation_date: 2021-02-01T17:24:09Z [Term] id: DDPHENO:0000686 name: development arrests at early culminant stage def: "Development cannot progress past the early culminant stage." [DDB:pf] synonym: "development arrests at mexican hat stage" BROAD [] is_a: DDPHENO:0000154 ! aberrant sorocarp development created_by: pfey creation_date: 2021-02-01T17:26:52Z [Term] id: DDPHENO:0000687 name: development arrests at mid culminant stage def: "Development cannot progress past the mid culminant stage." [DDB:pf] synonym: "development arrests at culminant stage" BROAD [] is_a: DDPHENO:0000154 ! aberrant sorocarp development created_by: pfey creation_date: 2021-02-01T17:29:26Z [Term] id: DDPHENO:0000688 name: development arrests at late culminant stage def: "Development cannot progress past the late culminant stage." [DDB:pf] synonym: "development arrests at culminant stage" BROAD [] is_a: DDPHENO:0000154 ! aberrant sorocarp development created_by: pfey creation_date: 2021-02-01T17:38:04Z [Term] id: DDPHENO:0000689 name: aberrant G protein-coupled receptor signaling def: "Deviation from the normal, usual, or expected events during G protein-coupled signaling." [DDB:pf] synonym: "aberrant G protein-coupled receptor signaling pathway" EXACT [] synonym: "aberrant GPCR signaling" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2021-04-28T10:46:00Z [Term] id: DDPHENO:0000690 name: aberrant spore cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation into spores during culmination." [DDB:pf] synonym: "aberrant sorocarp spore cell differentiation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation created_by: pfey creation_date: 2021-04-28T18:08:10Z [Term] id: DDPHENO:0000691 name: abolished spore cell differentiation def: "Complete inability for differentiation of spore cells during culmination." [DDB:pf] synonym: "abolished sorocarp spore cell differentiation" EXACT [] is_a: DDPHENO:0000690 ! aberrant spore cell differentiation created_by: pfey creation_date: 2021-04-28T18:11:09Z [Term] id: DDPHENO:0000692 name: decreased spore cell differentiation def: "Reduction in extent, amount, or degree of differentiation into spore cells during culmination." [DDB:pf] synonym: "decreased sorocarp spore cell differentiation" EXACT [] is_a: DDPHENO:0000690 ! aberrant spore cell differentiation created_by: pfey creation_date: 2021-04-28T18:12:42Z [Term] id: DDPHENO:0000693 name: abolished response to biotic stimulus def: "Complete inability for response to a biotic stimulus." [DDB:pf] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus created_by: pfey creation_date: 2021-04-28T18:19:37Z [Term] id: DDPHENO:0000694 name: aberrant cGMP-mediated signaling def: "Deviation from the normal, usual, or expected events during cGMP-mediated signaling." [DDB:pf] synonym: "aberrant cyclic GMP-mediated signaling" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2021-04-29T11:28:03Z [Term] id: DDPHENO:0000695 name: aberrant cAMP level def: "Deviation from the normal, usual, or expected cAMP level." [DDB:pf] synonym: "aberrant 3',5'-cyclic AMP level" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2021-04-29T18:22:43Z [Term] id: DDPHENO:0000696 name: decreased cAMP level def: "Reduction in extent, amount, or degree of the cAMP level." [DDB:pf] synonym: "decreased 3',5'-cyclic AMP level" EXACT [] is_a: DDPHENO:0000695 ! aberrant cAMP level created_by: pfey creation_date: 2021-04-29T18:25:17Z [Term] id: DDPHENO:0000697 name: increased cAMP level def: "Increase in extent, amount, or degree of cAMP level." [DDB:pf] synonym: "increased 3',5'-cyclic AMP level" EXACT [] is_a: DDPHENO:0000695 ! aberrant cAMP level created_by: pfey creation_date: 2021-04-29T18:26:58Z [Term] id: DDPHENO:0000698 name: aberrant epithelium-like organization def: "Deviation from the normal, usual, or expected events during epithelium-like organization." [DDB:pf] is_a: DDPHENO:0001015 ! aberrant culmination created_by: pfey creation_date: 2021-06-11T10:16:34Z [Term] id: DDPHENO:0000699 name: decreased epithelium-like organization def: "Reduction in extent, amount, or degree of epithelium-like organization." [DDB:pf] is_a: DDPHENO:0000698 ! aberrant epithelium-like organization created_by: pfey creation_date: 2021-06-11T10:17:55Z [Term] id: DDPHENO:0000700 name: abolished epithelium-like organization def: "Complete inability for epithelium-like organization." [DDB:pf] is_a: DDPHENO:0000698 ! aberrant epithelium-like organization created_by: pfey creation_date: 2021-06-11T10:19:25Z [Term] id: DDPHENO:0000701 name: aberrant aggregation territory size def: "Deviation from the normal, usual, or expected events during the development of the aggregation territory size." [DDB:pf] xref: PMID:18366659 "DDANAT:0000003" is_a: DDPHENO:0000483 ! aberrant aggregation created_by: pfey creation_date: 2021-06-14T17:50:44Z [Term] id: DDPHENO:0000702 name: decreased aggregation territory size def: "Reduction in relative or proportionate dimensions of the aggregation territory." [DDB:pf] is_a: DDPHENO:0000701 ! aberrant aggregation territory size created_by: pfey creation_date: 2021-06-14T17:52:35Z [Term] id: DDPHENO:0000703 name: increased aggregation territory size def: "Increase in relative or proportionate dimensions of the aggregation territory." [DDB:pf] is_a: DDPHENO:0000701 ! aberrant aggregation territory size created_by: pfey creation_date: 2021-06-14T17:54:12Z [Term] id: DDPHENO:0000704 name: abolished cAMP biosynthesis def: "Complete inability for cAMP biosynthesis." [DDB:pf] synonym: "abolished cAMP biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2021-06-15T15:51:38Z [Term] id: DDPHENO:0000705 name: decreased cAMP biosynthesis def: "Reduction in extent, amount, or degree of uptake of cAMP biosynthesis." [DDB:pf] synonym: "decreased cAMP biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2021-06-15T15:55:09Z [Term] id: DDPHENO:0000706 name: increased cAMP biosynthesis def: "Increase in extent, amount, or degree of cAMP biosynthesis." [DDB:pf] synonym: "increased cAMP biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2021-06-15T15:56:51Z [Term] id: DDPHENO:0000707 name: obsolete aberrant response to phleomycin def: "OBSOLETE. Deviation from the normal, usual, or expected during the response to phleomycin." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2021-06-21T15:50:58Z [Term] id: DDPHENO:0000708 name: decreased resistance to phleomycin def: "Decreased tolerance of the normal, usual, or expected events in the presence of phleomycin." [DDB:pf] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus created_by: pfey creation_date: 2021-06-21T15:52:31Z [Term] id: DDPHENO:0000709 name: increased resistance to phleomycin def: "Increased tolerance of the normal, usual, or expected events in the presence of phleomycin." [DDB:pf] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus created_by: pfey creation_date: 2021-06-21T15:53:45Z [Term] id: DDPHENO:0000710 name: aberrant response to bleomycin def: "Deviation from the normal, usual, or expected during the response to bleomycin." [DDB:pf] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus created_by: pfey creation_date: 2021-06-21T16:01:45Z [Term] id: DDPHENO:0000711 name: decreased resistance to bleomycin def: "Decreased tolerance of the normal, usual, or expected events in the presence of bleomycin." [DDB:pf] is_a: DDPHENO:0000710 ! aberrant response to bleomycin created_by: pfey creation_date: 2021-06-21T16:38:38Z [Term] id: DDPHENO:0000712 name: increased resistance to bleomycin def: "Increased tolerance of the normal, usual, or expected events in the presence of bleomycin." [DDB:pf] is_a: DDPHENO:0000710 ! aberrant response to bleomycin created_by: pfey creation_date: 2021-06-21T16:40:40Z [Term] id: DDPHENO:0000713 name: aberrant response to hydroxyurea def: "Deviation from the normal, usual, or expected events during the response to hydroxyurea." [DDB:pf] is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus created_by: pfey creation_date: 2021-06-21T17:23:28Z [Term] id: DDPHENO:0000714 name: increased resistance to hydroxyurea def: "Increase in extent, amount, or degree of resistance to hydroxyurea." [DDB:pf] is_a: DDPHENO:0000713 ! aberrant response to hydroxyurea created_by: pfey creation_date: 2021-06-21T17:24:34Z [Term] id: DDPHENO:0000715 name: decreased resistance to hydroxyurea def: "Decreased tolerance of the normal, usual, or expected events towards hydroxyurea." [DDB:pf] is_a: DDPHENO:0000713 ! aberrant response to hydroxyurea created_by: pfey creation_date: 2021-06-21T17:25:36Z [Term] id: DDPHENO:0000716 name: decreased regulation of siRNA processing def: "Reduction in level of modification of siRNA production involved in RNA interference." [DDB:pf] synonym: "decreased production of siRNA involved in RNAi" EXACT [] is_a: DDPHENO:0000022 ! aberrant regulation of siRNA processing created_by: pfey creation_date: 2021-06-24T12:40:11Z [Term] id: DDPHENO:0000717 name: mitotic M phase arrest def: "The M phase in the mitotic cell cycle cannot complete." [DDB:pf] synonym: "M phase mitotic cell cycle arrest" EXACT [] is_a: DDPHENO:0000234 ! aberrant mitosis created_by: pfey creation_date: 2021-06-24T14:40:05Z [Term] id: DDPHENO:0000718 name: increased post-lysosomal vacuole size def: "Increase in relative or proportionate dimensions of the post-lysosomal vacuole." [DDB:pf] synonym: "increased postlysosome size" EXACT [] is_a: DDPHENO:0001237 ! aberrant lysosome organization created_by: pfey creation_date: 2021-06-25T09:49:46Z [Term] id: DDPHENO:0000719 name: obsolete abolished protein tyrosin phosphorylation def: "OBSOLETE. Complete inability to phosphorylate a tyrosine residue of a protein." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2021-06-25T10:21:47Z [Term] id: DDPHENO:0000720 name: increased lateral pseudopodium retraction def: "Increase in extent, amount, or degree of suppression or retraction of lateral pseudopods." [DDB:pf] is_a: DDPHENO:0000477 ! aberrant lateral pseudopodium formation created_by: pfey creation_date: 2021-06-29T14:28:08Z [Term] id: DDPHENO:0000721 name: abolished prestalk gene expression def: "Complete inability for prestalk cell specific gene expression." [DDB:pf] synonym: "abolished prestalk cell specific gene expression" EXACT [] is_a: DDPHENO:0000365 ! aberrant prestalk gene expression is_a: DDPHENO:0001114 ! abolished gene expression created_by: pfey creation_date: 2021-08-31T17:39:53Z [Term] id: DDPHENO:0000722 name: abolished prespore gene expression def: "Complete inability for prespore cell specific gene expression." [DDB:pf] synonym: "abolished prespore cell specific gene expression" EXACT [] is_a: DDPHENO:0000370 ! aberrant prespore gene expression is_a: DDPHENO:0001114 ! abolished gene expression created_by: pfey creation_date: 2021-08-31T17:42:22Z [Term] id: DDPHENO:0000723 name: aberrant protein kinase activity def: "Deviation from the normal, usual, or expected events during protein kinase activity." [DDB:pf] comment: GO:0004672. is_a: DDPHENO:0001105 ! aberrant catalytic activity created_by: pfey creation_date: 2022-12-19T16:47:24Z [Term] id: DDPHENO:0000724 name: abolished protein tyrosine kinase activity def: "Complete absence of protein tyrosine kinase activity." [DDB:pf] is_a: DDPHENO:0000347 ! abolished protein kinase activity is_a: DDPHENO:0000727 ! aberrant protein tyrosine kinase activity created_by: pfey creation_date: 2022-12-19T16:51:28Z [Term] id: DDPHENO:0000725 name: decreased protein tyrosine kinase activity def: "Reduction in extent, amount, or degree of protein tyrosine kinase activity." [DDB:pf] is_a: DDPHENO:0000346 ! decreased protein kinase activity is_a: DDPHENO:0000727 ! aberrant protein tyrosine kinase activity created_by: pfey creation_date: 2022-12-19T16:54:09Z [Term] id: DDPHENO:0000726 name: increased protein tyrosine kinase activity def: "Increase in extent, amount, or degree of protein tyrosine kinase activity." [DDB:pf] is_a: DDPHENO:0000348 ! increased protein kinase activity is_a: DDPHENO:0000727 ! aberrant protein tyrosine kinase activity created_by: pfey creation_date: 2022-12-19T16:56:38Z [Term] id: DDPHENO:0000727 name: aberrant protein tyrosine kinase activity def: "Deviation from the normal, usual, or expected events during protein tyrosine kinase activity." [DDB:pf] comment: GO:0004713. is_a: DDPHENO:0000723 ! aberrant protein kinase activity created_by: pfey creation_date: 2022-12-19T17:05:36Z [Term] id: DDPHENO:0000728 name: aberrant transferase activity def: "Deviation from the normal, usual, or expected activity of a transferase." [DDB:pf] comment: GO:0016740. is_a: DDPHENO:0001171 ! aberrant molecular function created_by: pfey creation_date: 2022-12-19T18:09:25Z [Term] id: DDPHENO:0000729 name: aberrant histone H3K4 methyltransferase activity def: "Deviation from the normal, usual, or expected activity of histone H3K4 methyltransferase activity." [DDB:pf] comment: GO:0042800. is_a: DDPHENO:0000728 ! aberrant transferase activity created_by: pfey creation_date: 2022-12-19T18:15:00Z [Term] id: DDPHENO:0000730 name: abolished histone H3K4 methyltransferase activity def: "Complete absence of histone H3K4 methyltransferase activity." [DDB:pf] is_a: DDPHENO:0000729 ! aberrant histone H3K4 methyltransferase activity created_by: pfey creation_date: 2022-12-19T18:16:21Z [Term] id: DDPHENO:0000731 name: aberrant histone H3K79 methyltransferase activity def: "Deviation from the normal, usual, or expected activity of histone H3K79 methyltransferase activity." [DDB:pf] comment: GO:0031151. is_a: DDPHENO:0000728 ! aberrant transferase activity created_by: pfey creation_date: 2022-12-19T18:28:20Z [Term] id: DDPHENO:0000732 name: abolished histone H3K79 methyltransferase activity def: "Complete absence of histone H3K79 methyltransferase activity." [DDB:pf] is_a: DDPHENO:0000731 ! aberrant histone H3K79 methyltransferase activity created_by: pfey creation_date: 2022-12-19T18:29:17Z [Term] id: DDPHENO:0000733 name: aberrant histone H3K9 methyltransferase activity def: "Deviation from the normal, usual, or expected activity of histone H3K9 methyltransferase activity." [DDB:pf] comment: GO:0046974. is_a: DDPHENO:0000728 ! aberrant transferase activity created_by: pfey creation_date: 2022-12-20T10:59:30Z [Term] id: DDPHENO:0000734 name: abolished histone H3K9 methyltransferase activity def: "Complete absence of histone H3K9 methyltransferase activity." [DDB:pf] is_a: DDPHENO:0000733 ! aberrant histone H3K9 methyltransferase activity created_by: pfey creation_date: 2022-12-20T11:02:12Z [Term] id: DDPHENO:0000735 name: aberrant myosin heavy chain kinase activity def: "Deviation from the normal, usual, or expected events during myosin heavy chain kinase activity." [DDB:pf] comment: GO:0016905. is_a: DDPHENO:0000723 ! aberrant protein kinase activity created_by: pfey creation_date: 2022-12-20T11:08:36Z [Term] id: DDPHENO:0000736 name: abolished myosin heavy chain kinase activity def: "Complete absence of myosin heavy chain kinase activity." [DDB:pf] is_a: DDPHENO:0000735 ! aberrant myosin heavy chain kinase activity created_by: pfey creation_date: 2022-12-20T11:16:50Z [Term] id: DDPHENO:0000737 name: aberrant DNA-methyltransferase activity def: "Deviation from the normal, usual, or expected activity of DNA methyltransferase activity." [DDB:pf] comment: GO:0009008. synonym: "aberrant DNA methyltransferase activity" EXACT [] is_a: DDPHENO:0000728 ! aberrant transferase activity created_by: pfey creation_date: 2022-12-20T11:33:41Z [Term] id: DDPHENO:0000738 name: decreased DNA-methyltransferase activity def: "Reduction in extent, amount, or degree of DNA methyltransferase activity." [DDB:pf] synonym: "decreased DNA methyltransferase activity" EXACT [] is_a: DDPHENO:0000737 ! aberrant DNA-methyltransferase activity created_by: pfey creation_date: 2022-12-20T11:35:45Z [Term] id: DDPHENO:0000739 name: aberrant regulation of MAPK cascade def: "Deviation from the normal, usual, or expected events during the regulation of MAPK cascade." [DDB:pf] comment: GO:0043408. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2022-12-20T16:26:55Z [Term] id: DDPHENO:0000740 name: abolished regulation of MAPK cascade def: "Complete inability to regulate the MAPK cascade." [DDB:pf] is_a: DDPHENO:0000739 ! aberrant regulation of MAPK cascade created_by: pfey creation_date: 2022-12-20T16:28:14Z [Term] id: DDPHENO:0000741 name: aberrant protein kinase B signaling def: "Deviation from the normal, usual, or expected events during protein kinase B signaling." [DDB:pf] comment: GO:0043491. synonym: "aberrant PKB signaling" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2022-12-20T16:37:59Z [Term] id: DDPHENO:0000742 name: decreased protein kinase B signaling def: "Reduction in extent, amount, or degree of activation of protein kinase B signaling." [DDB:pf] synonym: "decreased PKB signaling" EXACT [] is_a: DDPHENO:0000741 ! aberrant protein kinase B signaling created_by: pfey creation_date: 2022-12-20T16:40:41Z [Term] id: DDPHENO:0000743 name: increased protein kinase B signaling def: "Increase in extent, amount, or degree of protein kinase B signaling." [DDB:pf] synonym: "increased PKB signaling" EXACT [] is_a: DDPHENO:0000741 ! aberrant protein kinase B signaling created_by: pfey creation_date: 2022-12-20T16:44:24Z [Term] id: DDPHENO:0000744 name: abolished protein kinase B signaling def: "Complete absence of protein kinase B signaling." [DDB:pf] synonym: "abolished PKB signaling" EXACT [] is_a: DDPHENO:0000741 ! aberrant protein kinase B signaling created_by: pfey creation_date: 2022-12-20T16:45:53Z [Term] id: DDPHENO:0000745 name: aberrant prenylcysteine carboxyl methyltransferase activity def: "Deviation from the normal, usual, or expected activity of prenylcysteine carboxyl methyltransferase activity." [DDB:pf] comment: GO:0004671. synonym: "aberrant protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity" EXACT [] is_a: DDPHENO:0000728 ! aberrant transferase activity created_by: pfey creation_date: 2023-01-09T15:16:32Z [Term] id: DDPHENO:0000746 name: abolished prenylcysteine carboxyl methyltransferase activity def: "Complete absence of prenylcysteine carboxyl methyltransferase activity." [DDB:pf] comment: GO:0004671. synonym: "abolished protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity" EXACT [] is_a: DDPHENO:0000745 ! aberrant prenylcysteine carboxyl methyltransferase activity created_by: pfey creation_date: 2023-01-09T15:19:30Z [Term] id: DDPHENO:0000747 name: aberrant cellular DNA damage response def: "Deviation from the normal, usual, or expected events during the cellular DNA damage response." [DDB:pf] comment: GO:0006974. synonym: "aberrant cellular response to DNA damage stimulus" EXACT [] synonym: "aberrant DNA damage response" EXACT [] is_a: DDPHENO:0001034 ! aberrant cellular response to stress created_by: pfey creation_date: 2023-01-09T15:26:54Z [Term] id: DDPHENO:0000748 name: aberrant phosphatase activity def: "Deviation from the normal, usual, or expected events during phosphatase activity." [DDB:pf] comment: GO:0016791. is_a: DDPHENO:0001105 ! aberrant catalytic activity created_by: pfey creation_date: 2022-12-20T17:07:12Z [Term] id: DDPHENO:0000749 name: decreased phosphatase activity def: "Reduction in extent, amount, or degree of phosphatase activity." [DDB:pf] is_a: DDPHENO:0000748 ! aberrant phosphatase activity created_by: pfey creation_date: 2022-12-20T17:10:30Z [Term] id: DDPHENO:0000750 name: increased phosphatase activity def: "Increase in extent, amount, or degree of phosphatase activity." [DDB:pf] is_a: DDPHENO:0000748 ! aberrant phosphatase activity created_by: pfey creation_date: 2022-12-20T17:13:55Z [Term] id: DDPHENO:0000751 name: abolished phosphatase activity def: "Complete absence of phosphatase activity." [DDB:pf] is_a: DDPHENO:0000748 ! aberrant phosphatase activity created_by: pfey creation_date: 2022-12-20T17:15:26Z [Term] id: DDPHENO:0000752 name: aberrant protein tyrosine phosphatase activity def: "Deviation from the normal, usual, or expected events during protein tyrosine phosphatase activity." [DDB:pf] comment: GO:0004725. is_a: DDPHENO:0000748 ! aberrant phosphatase activity created_by: pfey creation_date: 2022-12-20T17:17:07Z [Term] id: DDPHENO:0000753 name: decreased protein tyrosine phosphatase activity def: "Reduction in extent, amount, or degree of protein tyrosine phosphatase activity." [DDB:pf] is_a: DDPHENO:0000749 ! decreased phosphatase activity is_a: DDPHENO:0000752 ! aberrant protein tyrosine phosphatase activity created_by: pfey creation_date: 2022-12-20T17:20:24Z [Term] id: DDPHENO:0000754 name: increased protein tyrosine phosphatase activity def: "Increase in extent, amount, or degree of protein tyrosine phosphatase activity." [DDB:pf] is_a: DDPHENO:0000750 ! increased phosphatase activity is_a: DDPHENO:0000752 ! aberrant protein tyrosine phosphatase activity created_by: pfey creation_date: 2022-12-20T17:22:53Z [Term] id: DDPHENO:0000755 name: abolished protein tyrosine phosphatase activity def: "Complete absence of protein tyrosine phosphatase activity." [DDB:pf] is_a: DDPHENO:0000751 ! abolished phosphatase activity is_a: DDPHENO:0000752 ! aberrant protein tyrosine phosphatase activity created_by: pfey creation_date: 2022-12-20T17:26:46Z [Term] id: DDPHENO:0000756 name: aberrant STAT signaling pathway def: "Deviation from the normal, usual, or expected events during the STAT signaling pathway." [DDB:pf] comment: GO:0097696. synonym: "aberrant receptor signaling pathway via STAT" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2022-12-20T17:41:05Z [Term] id: DDPHENO:0000757 name: abolished STAT signaling pathway def: "Complete absence of the STAT signaling pathway." [DDB:pf] synonym: "abolished receptor signaling pathway via STAT" EXACT [] is_a: DDPHENO:0000756 ! aberrant STAT signaling pathway created_by: pfey creation_date: 2022-12-20T17:51:47Z [Term] id: DDPHENO:0000758 name: aberrant regulation of STAT signaling pathway def: "Deviation from the normal, usual, or expected events during the regulation of the STAT signaling pathway." [DDB:pf] comment: GO:1904892. synonym: "aberrant regulation of receptor signaling pathway via STAT" EXACT [] is_a: DDPHENO:0000756 ! aberrant STAT signaling pathway created_by: pfey creation_date: 2022-12-20T17:58:25Z [Term] id: DDPHENO:0000759 name: decreased regulation of STAT signaling pathway def: "Reduction in extent, amount, or degree of the regulation of STAT signaling pathway." [DDB:pf] synonym: "decreased regulation of receptor signaling pathway via STAT" EXACT [] is_a: DDPHENO:0000758 ! aberrant regulation of STAT signaling pathway created_by: pfey creation_date: 2022-12-20T18:09:03Z [Term] id: DDPHENO:0000760 name: abolished regulation of STAT signaling pathway def: "Complete absence of the regulation of STAT signalling pathway." [DDB:pf] synonym: "abolished regulation of receptor signaling pathway via STAT" EXACT [] is_a: DDPHENO:0000757 ! abolished STAT signaling pathway is_a: DDPHENO:0000758 ! aberrant regulation of STAT signaling pathway created_by: pfey creation_date: 2022-12-20T18:11:47Z [Term] id: DDPHENO:0000761 name: aberrant Ras protein signal transduction def: "Deviation from the normal, usual, or expected events during Ras protein signal transduction." [DDB:pf] comment: GO:0007265. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2022-12-20T18:21:10Z [Term] id: DDPHENO:0000762 name: decreased Ras protein signal transduction def: "Reduction in extent, amount, or degree of activation of Ras protein signal transduction." [DDB:pf] is_a: DDPHENO:0000761 ! aberrant Ras protein signal transduction created_by: pfey creation_date: 2022-12-20T18:23:48Z [Term] id: DDPHENO:0000763 name: increased Ras protein signal transduction def: "Increase in extent, amount, or degree of Ras protein signal transduction." [DDB:pf] is_a: DDPHENO:0000761 ! aberrant Ras protein signal transduction created_by: pfey creation_date: 2022-12-20T18:25:16Z [Term] id: DDPHENO:0000764 name: abolished Ras protein signal transduction def: "Complete absence of Ras protein signal transduction." [DDB:pf] is_a: DDPHENO:0000761 ! aberrant Ras protein signal transduction created_by: pfey creation_date: 2022-12-20T18:26:23Z [Term] id: DDPHENO:0000765 name: aberrant protein-containing complex assembly def: "Deviation from the normal, usual, or expected events during protein-containing complex assembly." [DDB:pf] synonym: "aberrant cellular protein complex assembly" EXACT [] is_a: DDPHENO:0001042 ! aberrant cellular component organization created_by: pfey creation_date: 2022-12-20T19:33:32Z [Term] id: DDPHENO:0000766 name: decreased cell-cell self recognition def: "Reduction in extent, amount, or degree of cell-cell self recognition." [DDB:pf] is_a: DDPHENO:0000122 ! aberrant cell-cell self recognition created_by: pfey creation_date: 2022-12-20T19:35:59Z [Term] id: DDPHENO:0000767 name: decreased cellular DNA damage response def: "Decreased tolerance of the normal, usual, or expected event during cellular DNA damage response." [DDB:pf] comment: GO:0006974. synonym: "decreased cellular response to DNA damage stimulus" EXACT [] synonym: "decreased DNA damage response" EXACT [] is_a: DDPHENO:0000747 ! aberrant cellular DNA damage response created_by: pfey creation_date: 2023-01-09T15:29:03Z [Term] id: DDPHENO:0000768 name: increased cellular DNA damage response def: "Increased tolerance of the normal, usual, or expected events during cellular DNA damage response." [DDB:pf] comment: GO:0006974. synonym: "increased cellular response to DNA damage stimulus" EXACT [] synonym: "increased DNA damage response" EXACT [] is_a: DDPHENO:0000747 ! aberrant cellular DNA damage response created_by: pfey creation_date: 2023-01-09T15:32:04Z [Term] id: DDPHENO:0000769 name: abolished cellular DNA damage response def: "Complete inability to respond to DNA damage." [DDB:pf] comment: GO:0006974. synonym: "abolished cellular response to DNA damage stimulus" EXACT [] synonym: "abolished DNA damage response" EXACT [] is_a: DDPHENO:0000747 ! aberrant cellular DNA damage response created_by: pfey creation_date: 2023-01-09T15:34:30Z [Term] id: DDPHENO:0000770 name: aberrant programmed cell death def: "Deviation from the normal, usual, or expected events during programmed cell death." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation created_by: pfey creation_date: 2023-03-08T14:23:35Z [Term] id: DDPHENO:0000771 name: increased programmed cell death def: "Increase in extent, amount, or degree of programmed cell death." [DDB:pf] is_a: DDPHENO:0000770 ! aberrant programmed cell death created_by: pfey creation_date: 2023-03-08T14:27:52Z [Term] id: DDPHENO:0000772 name: decreased programmed cell death def: "Reduction in extent, amount, or degree of programmed cell death." [DDB:pf] is_a: DDPHENO:0000770 ! aberrant programmed cell death created_by: pfey creation_date: 2023-03-08T14:30:01Z [Term] id: DDPHENO:0000773 name: aberrant signaling receptor activity def: "Deviation from the normal, usual, or expected activity of a signaling receptor." [DDB:pf] is_a: DDPHENO:0001171 ! aberrant molecular function created_by: pfey creation_date: 2023-03-08T17:27:56Z [Term] id: DDPHENO:0000774 name: aberrant G protein-coupled chemorepellent receptor signaling pathway def: "Deviation from the normal, usual, or expected activity of a G-protein coupled chemorepellent receptor activity." [DDB:pf] comment: GO:0140986. synonym: "aberrant G protein-coupled chemorepellent receptor activity" EXACT [] is_a: DDPHENO:0000689 ! aberrant G protein-coupled receptor signaling created_by: pfey creation_date: 2023-03-08T17:31:23Z [Term] id: DDPHENO:0000775 name: decreased G protein-coupled chemorepellent receptor signaling pathway def: "Reduction in extent, amount, or degree of G-protein coupled chemorepellent receptor activity." [DDB:pf] synonym: "decreased G protein-coupled chemorepellent receptor activity" EXACT [] is_a: DDPHENO:0000774 ! aberrant G protein-coupled chemorepellent receptor signaling pathway created_by: pfey creation_date: 2023-03-08T17:34:39Z [Term] id: DDPHENO:0000776 name: increased G protein-coupled chemorepellent receptor signaling pathway def: "Increased in extent, amount, or degree of G-protein coupled chemorepellent receptor activity." [DDB:pf] synonym: "increased G protein-coupled chemorepellent receptor activity" EXACT [] is_a: DDPHENO:0000774 ! aberrant G protein-coupled chemorepellent receptor signaling pathway created_by: pfey creation_date: 2023-03-08T17:53:51Z [Term] id: DDPHENO:0000777 name: abolished G protein-coupled chemorepellent receptor signaling pathway def: "Complete absence of G-protein coupled chemorepellent receptor activity." [DDB:pf] synonym: "abolished G protein-coupled chemorepellent receptor activity" EXACT [] is_a: DDPHENO:0000774 ! aberrant G protein-coupled chemorepellent receptor signaling pathway created_by: pfey creation_date: 2023-03-08T17:56:16Z [Term] id: DDPHENO:0000778 name: decreased protein localization to mitotic actomyosin contractile ring def: "Reduction in extent, amount, or degree of protein localization to mitotic actomyosin contractile ring." [DDB:pf] is_a: DDPHENO:0000796 ! aberrant protein localization to mitotic actomyosin contractile ring created_by: pfey creation_date: 2023-03-16T17:36:03Z [Term] id: DDPHENO:0000779 name: increased heterotrimeric G-protein complex assembly def: "Increase in extent, amount, or degree of heterotrimeric G-protein complex assembly." [DDB:pf] is_a: DDPHENO:0000806 ! aberrant heterotrimeric G-protein complex assembly created_by: pfey creation_date: 2023-03-17T17:58:26Z [Term] id: DDPHENO:0000782 name: aberrant DNA (cytosine-5-)-methyltransferase activity def: "Deviation from the normal, usual, or expected activity of DNA cytosine-5-)-methyltransferase activity." [DDB:pf] comment: GO:0003886. synonym: "aberrant DNA 5-cytosine methylase activity" EXACT [] is_a: DDPHENO:0000737 ! aberrant DNA-methyltransferase activity created_by: pfey creation_date: 2023-03-13T14:05:10Z [Term] id: DDPHENO:0000783 name: decreased DNA (cytosine-5-)-methyltransferase activity def: "Reduction in extent, amount, or degree of DNA (cytosine-5-)-methyltransferase activity." [DDB:pf] synonym: "decreased DNA 5-cytosine methylase activity" EXACT [] is_a: DDPHENO:0000738 ! decreased DNA-methyltransferase activity is_a: DDPHENO:0000782 ! aberrant DNA (cytosine-5-)-methyltransferase activity created_by: pfey creation_date: 2023-03-13T14:06:25Z [Term] id: DDPHENO:0000784 name: abolished DNA (cytosine-5-)-methyltransferase activity def: "Complete absence of DNA (cytosine-5-)-methyltransferase activity." [DDB:pf] synonym: "abolished DNA 5-cytosine methylase activity" EXACT [] is_a: DDPHENO:0000782 ! aberrant DNA (cytosine-5-)-methyltransferase activity created_by: pfey creation_date: 2023-03-13T15:22:57Z [Term] id: DDPHENO:0000785 name: aberrant molecular function regulator activity def: "Deviation from the normal, usual, or expected molecular function regulator activity." [DDB:pf] comment: GO:0098772. is_a: DDPHENO:0001105 ! aberrant catalytic activity created_by: pfey creation_date: 2023-03-13T17:41:24Z [Term] id: DDPHENO:0000786 name: aberrant adenylate cyclase regulator activity def: "Deviation from the normal, usual, or expected adenylate cyclase regulator activity." [DDB:pf] comment: GO:0010854. is_a: DDPHENO:0000785 ! aberrant molecular function regulator activity created_by: pfey creation_date: 2023-03-13T17:44:47Z [Term] id: DDPHENO:0000787 name: decreased adenylate cyclase regulator activity def: "A reduction in extent, amount, or degree of adenylate cyclase regulator activity." [DDB:pf] comment: GO:0010854. is_a: DDPHENO:0000786 ! aberrant adenylate cyclase regulator activity created_by: pfey creation_date: 2023-03-13T17:47:16Z [Term] id: DDPHENO:0000788 name: abolished adenylate cyclase regulator activity def: "Complete absence of adenylate cyclase regulator activity." [DDB:pf] comment: GO:0010854. is_a: DDPHENO:0000786 ! aberrant adenylate cyclase regulator activity created_by: pfey creation_date: 2023-03-13T18:13:21Z [Term] id: DDPHENO:0000789 name: aberrant adenylate cyclase activator activity def: "Deviation from the normal, usual, or expected adenylate cyclase activator activity." [DDB:pf] comment: GO:0010856. is_a: DDPHENO:0000786 ! aberrant adenylate cyclase regulator activity created_by: pfey creation_date: 2023-03-13T18:18:32Z [Term] id: DDPHENO:0000790 name: decreased adenylate cyclase activator activity def: "Reduction in extent, amount, or degree of adenylate cyclase activator activity." [DDB:pf] comment: GO:0010856. is_a: DDPHENO:0000787 ! decreased adenylate cyclase regulator activity is_a: DDPHENO:0000789 ! aberrant adenylate cyclase activator activity created_by: pfey creation_date: 2023-03-13T18:19:16Z [Term] id: DDPHENO:0000791 name: abolished adenylate cyclase activator activity def: "Complete absence of adenylate cyclase activator activity." [DDB:pf] comment: GO:0010856. is_a: DDPHENO:0000788 ! abolished adenylate cyclase regulator activity is_a: DDPHENO:0000789 ! aberrant adenylate cyclase activator activity created_by: pfey creation_date: 2023-03-13T18:20:48Z [Term] id: DDPHENO:0000792 name: aberrant protein kinase regulator activity def: "Deviation from the normal, usual, or expected protein kinase regulator activity." [DDB:pf] comment: GO:0019887. is_a: DDPHENO:0000785 ! aberrant molecular function regulator activity created_by: pfey creation_date: 2023-03-13T18:41:58Z [Term] id: DDPHENO:0000793 name: increased protein kinase regulator activity def: "Increase in extent, amount, or degree of protein kinase regulator activity." [DDB:pf] comment: GO:0019887. is_a: DDPHENO:0000792 ! aberrant protein kinase regulator activity created_by: pfey creation_date: 2023-03-13T18:44:36Z [Term] id: DDPHENO:0000794 name: decreased protein kinase regulator activity def: "Reduction in extent, amount, or degree of protein kinase regulator activity." [DDB:pf] comment: GO:0019887. is_a: DDPHENO:0000792 ! aberrant protein kinase regulator activity created_by: pfey creation_date: 2023-03-13T18:46:09Z [Term] id: DDPHENO:0000795 name: abolished protein kinase regulator activity def: "Complete absence of protein kinase regulator activity." [DDB:pf] comment: GO:0019887. is_a: DDPHENO:0000792 ! aberrant protein kinase regulator activity created_by: pfey creation_date: 2023-03-13T18:47:51Z [Term] id: DDPHENO:0000796 name: aberrant protein localization to mitotic actomyosin contractile ring def: "Deviation from the normal, usual, or expected protein localization to mitotic actomyosin contractile ring." [DDB:pf] comment: GO:1904498. is_a: DDPHENO:0000149 ! aberrant cytokinesis created_by: pfey creation_date: 2023-03-13T18:56:02Z [Term] id: DDPHENO:0000797 name: abolished protein localization to mitotic actomyosin contractile ring def: "Complete inability for protein localization to mitotic actomyosin contractile ring." [DDB:pf] comment: GO:1904498. is_a: DDPHENO:0000796 ! aberrant protein localization to mitotic actomyosin contractile ring created_by: pfey creation_date: 2023-03-13T19:02:59Z [Term] id: DDPHENO:0000798 name: aberrant GTPase regulator activity def: "Deviation from the normal, usual, or expected GTPase regulator activity." [DDB:pf] comment: GO:0030695. is_a: DDPHENO:0000785 ! aberrant molecular function regulator activity created_by: pfey creation_date: 2023-03-13T19:20:39Z [Term] id: DDPHENO:0000799 name: aberrant GTPase activator activity def: "Deviation from the normal, usual, or expected GTPase activator activity." [DDB:pf] comment: GO:0005096. is_a: DDPHENO:0000798 ! aberrant GTPase regulator activity created_by: pfey creation_date: 2023-03-13T19:24:53Z [Term] id: DDPHENO:0000800 name: increased GTPase activator activity def: "Increase in extent, amount, or degree of GTPase activator activity." [DDB:pf] comment: GO:0005096. is_a: DDPHENO:0000799 ! aberrant GTPase activator activity created_by: pfey creation_date: 2023-03-13T19:26:09Z [Term] id: DDPHENO:0000801 name: decreased GTPase activator activity def: "Reduction in extent, amount, or degree of GTPase activator activity." [DDB:pf] comment: GO:0005096. is_a: DDPHENO:0000799 ! aberrant GTPase activator activity created_by: pfey creation_date: 2023-03-13T19:31:05Z [Term] id: DDPHENO:0000802 name: abolished GTPase activator activity def: "Complete absence of GTPase activator activity." [DDB:pf] is_a: DDPHENO:0000799 ! aberrant GTPase activator activity created_by: pfey creation_date: 2023-03-13T20:29:44Z [Term] id: DDPHENO:0000803 name: aberrant autophagosome maturation def: "Deviation from the normal, usual, or expected events during autophagosome maturation." [DDB:pf] comment: GO:0097352. is_a: DDPHENO:0000212 ! aberrant macroautophagy created_by: pfey creation_date: 2023-03-13T20:36:01Z [Term] id: DDPHENO:0000804 name: decreased autophagosome maturation def: "Reduction in extent, amount, or degree of autophagosome maturation." [DDB:pf] is_a: DDPHENO:0000803 ! aberrant autophagosome maturation created_by: pfey creation_date: 2023-03-13T20:37:43Z [Term] id: DDPHENO:0000805 name: abolished autophagosome maturation def: "Complete absence of autophagosome maturation." [DDB:pf] is_a: DDPHENO:0000803 ! aberrant autophagosome maturation created_by: pfey creation_date: 2023-03-13T20:38:52Z [Term] id: DDPHENO:0000806 name: aberrant heterotrimeric G-protein complex assembly def: "Deviation from the normal, usual, or expected events during heterotrimeric G-protein complex assembly." [DDB:pf] comment: GO:1902605. is_a: DDPHENO:0000765 ! aberrant protein-containing complex assembly created_by: pfey creation_date: 2023-03-13T20:46:07Z [Term] id: DDPHENO:0000807 name: decreased heterotrimeric G-protein complex assembly def: "Reduction in extent, amount, or degree of heterotrimeric G-protein complex assembly." [DDB:pf] is_a: DDPHENO:0000806 ! aberrant heterotrimeric G-protein complex assembly created_by: pfey creation_date: 2023-03-13T20:50:18Z [Term] id: DDPHENO:0000808 name: abolished heterotrimeric G-protein complex assembly def: "Complete absence of heterotrimeric G-protein complex assembly." [DDB:pf] is_a: DDPHENO:0000806 ! aberrant heterotrimeric G-protein complex assembly created_by: pfey creation_date: 2023-03-13T20:51:36Z [Term] id: DDPHENO:0000809 name: aberrant protein metabolic process def: "Deviation from the normal, usual, or expected events during protein metabolic process." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2023-03-13T23:04:53Z [Term] id: DDPHENO:0000810 name: aberrant proteasomal protein catabolic process def: "Deviation from the normal, usual, or expected events during proteasomal protein catabolic process." [DDB:pf] comment: GO:0010498. is_a: DDPHENO:0000809 ! aberrant protein metabolic process created_by: pfey creation_date: 2023-03-13T23:06:27Z [Term] id: DDPHENO:0000811 name: decreased proteasomal protein catabolic process def: "Reduction in extent, amount, or degree of proteasomal protein catabolic process." [DDB:pf] is_a: DDPHENO:0000810 ! aberrant proteasomal protein catabolic process created_by: pfey creation_date: 2023-03-13T23:07:39Z [Term] id: DDPHENO:0000812 name: abolished proteasomal protein catabolic process def: "Complete absence of proteasomal protein catabolic process." [DDB:pf] is_a: DDPHENO:0000810 ! aberrant proteasomal protein catabolic process created_by: pfey creation_date: 2023-03-13T23:09:23Z [Term] id: DDPHENO:0000813 name: aberrant ubiquitin-dependent protein catabolic process def: "Deviation from the normal, usual, or expected events during ubiquitin-dependent protein catabolic process." [DDB:pf] comment: GO:0006511. is_a: DDPHENO:0000809 ! aberrant protein metabolic process created_by: pfey creation_date: 2023-03-13T23:15:25Z [Term] id: DDPHENO:0000814 name: decreased ubiquitin-dependent protein catabolic process def: "Reduction in extent, amount, or degree of ubiquitin-dependent protein catabolic process." [DDB:pf] is_a: DDPHENO:0000813 ! aberrant ubiquitin-dependent protein catabolic process created_by: pfey creation_date: 2023-03-13T23:16:32Z [Term] id: DDPHENO:0000815 name: abolished ubiquitin-dependent protein catabolic process def: "Complete absence of ubiquitin-dependent protein catabolic process." [DDB:pf] is_a: DDPHENO:0000813 ! aberrant ubiquitin-dependent protein catabolic process created_by: pfey creation_date: 2023-03-13T23:18:49Z [Term] id: DDPHENO:0000816 name: abolished programmed cell death def: "Complete absence of programmed cell death." [DDB:pf] is_a: DDPHENO:0000770 ! aberrant programmed cell death created_by: pfey creation_date: 2023-03-14T14:13:46Z [Term] id: DDPHENO:0000817 name: decreased regulation of MAPK cascade def: "Reduction in extent, amount, or degree of regulation of MAPK cascade." [DDB:pf] is_a: DDPHENO:0000739 ! aberrant regulation of MAPK cascade created_by: pfey creation_date: 2023-03-14T14:40:41Z [Term] id: DDPHENO:0000818 name: increased regulation of MAPK cascade def: "Increase in extent, amount, or degree of regulation of MAPK cascade." [DDB:pf] is_a: DDPHENO:0000739 ! aberrant regulation of MAPK cascade created_by: pfey creation_date: 2023-03-14T14:43:42Z [Term] id: DDPHENO:0000819 name: aberrant TORC2 signaling def: "Deviation from the normal, usual, or expected events during TORC2 signaling." [DDB:pf] comment: GO:0038203. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2023-03-14T14:53:48Z [Term] id: DDPHENO:0000820 name: decreased TORC2 signaling def: "Reduction in extent, amount, or degree of TORC2 signaling." [DDB:pf] is_a: DDPHENO:0000819 ! aberrant TORC2 signaling created_by: pfey creation_date: 2023-03-14T14:55:42Z [Term] id: DDPHENO:0000821 name: abolished TORC2 signaling def: "Complete absence of TORC2 signaling." [DDB:pf] is_a: DDPHENO:0000819 ! aberrant TORC2 signaling created_by: pfey creation_date: 2023-03-14T14:56:38Z [Term] id: DDPHENO:0000822 name: increased TORC2 signaling def: "Increase in extent, amount, or degree of TORC2 signaling." [DDB:pf] is_a: DDPHENO:0000819 ! aberrant TORC2 signaling created_by: pfey creation_date: 2023-03-14T14:58:17Z [Term] id: DDPHENO:0000823 name: aberrant Rab protein signal transduction def: "Deviation from the normal, usual, or expected events during Rab protein signal transduction." [DDB:pf] comment: GO:0032482. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2023-03-14T16:33:25Z [Term] id: DDPHENO:0000824 name: decreased Rab protein signal transduction def: "Reduction in extent, amount, or degree of activation of Rab protein signal transduction." [DDB:pf] is_a: DDPHENO:0000823 ! aberrant Rab protein signal transduction created_by: pfey creation_date: 2023-03-14T16:35:14Z [Term] id: DDPHENO:0000825 name: increased Rab protein signal transduction def: "Increase in extent, amount, or degree of Rab protein signal transduction." [DDB:pf] is_a: DDPHENO:0000823 ! aberrant Rab protein signal transduction created_by: pfey creation_date: 2023-03-14T16:47:48Z [Term] id: DDPHENO:0000826 name: abolished Rab protein signal transduction def: "Complete absence of Rab protein signal transduction." [DDB:pf] is_a: DDPHENO:0000823 ! aberrant Rab protein signal transduction created_by: pfey creation_date: 2023-03-14T16:48:54Z [Term] id: DDPHENO:0000827 name: aberrant Rap protein signal transduction def: "Deviation from the normal, usual, or expected events during Rap protein signal transduction." [DDB:pf] comment: GO:0032486. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2023-03-14T16:50:12Z [Term] id: DDPHENO:0000828 name: decreased Rap protein signal transduction def: "Reduction in extent, amount, or degree of activation of Rap protein signal transduction." [DDB:pf] is_a: DDPHENO:0000827 ! aberrant Rap protein signal transduction created_by: pfey creation_date: 2023-03-14T16:51:25Z [Term] id: DDPHENO:0000829 name: increased Rap protein signal transduction def: "Increase in extent, amount, or degree of Rap protein signal transduction." [DDB:pf] is_a: DDPHENO:0000827 ! aberrant Rap protein signal transduction created_by: pfey creation_date: 2023-03-14T16:53:09Z [Term] id: DDPHENO:0000830 name: abolished Rap protein signal transduction def: "Complete absence of Rap protein signal transduction." [DDB:pf] is_a: DDPHENO:0000827 ! aberrant Rap protein signal transduction created_by: pfey creation_date: 2023-03-14T16:54:00Z [Term] id: DDPHENO:0000831 name: aberrant Rac protein signal transduction def: "Deviation from the normal, usual, or expected events during Rac protein signal transduction." [DDB:pf] comment: GO:0016601. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2023-03-14T16:55:28Z [Term] id: DDPHENO:0000832 name: decreased Rac protein signal transduction def: "Reduction in extent, amount, or degree of activation of Rac protein signal transduction." [DDB:pf] is_a: DDPHENO:0000831 ! aberrant Rac protein signal transduction created_by: pfey creation_date: 2023-03-14T16:56:28Z [Term] id: DDPHENO:0000833 name: increased Rac protein signal transduction def: "Increase in extent, amount, or degree of Rac protein signal transduction." [DDB:pf] is_a: DDPHENO:0000831 ! aberrant Rac protein signal transduction created_by: pfey creation_date: 2023-03-14T16:57:16Z [Term] id: DDPHENO:0000834 name: abolished Rac protein signal transduction def: "Complete absence of Rac protein signal transduction." [DDB:pf] is_a: DDPHENO:0000831 ! aberrant Rac protein signal transduction created_by: pfey creation_date: 2023-03-14T16:57:58Z [Term] id: DDPHENO:0000835 name: aberrant small GTPase mediated signal transduction def: "Deviation from the normal, usual, or expected events during small GTPase mediated signal transduction." [DDB:pf] comment: GO:0007264. is_a: DDPHENO:0001118 ! aberrant signal transduction created_by: pfey creation_date: 2023-03-14T17:08:48Z [Term] id: DDPHENO:0000836 name: decreased small GTPase mediated signal transduction def: "Reduction in extent, amount, or degree of small GTPase mediated signal transduction." [DDB:pf] is_a: DDPHENO:0000835 ! aberrant small GTPase mediated signal transduction created_by: pfey creation_date: 2023-03-14T17:12:46Z [Term] id: DDPHENO:0000837 name: increased small GTPase mediated signal transduction def: "Increase in extent, amount, or degree of small GTPase mediated signal transduction." [DDB:pf] is_a: DDPHENO:0000835 ! aberrant small GTPase mediated signal transduction created_by: pfey creation_date: 2023-03-14T17:13:42Z [Term] id: DDPHENO:0000838 name: abolished small GTPase mediated signal transduction def: "Complete absence of small GTPase mediated signal transduction." [DDB:pf] is_a: DDPHENO:0000835 ! aberrant small GTPase mediated signal transduction created_by: pfey creation_date: 2023-03-14T17:14:29Z [Term] id: DDPHENO:0001001 name: obsolete aberrant initiation of development def: "OBSOLETE. Deviation from the normal, usual, or expected events duringninitiation of development." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001002 name: aberrant organelle morphology def: "Deviation from the normal, usual, or expected morphology of organelles." [DDB:pg] comment: Child of GO:0006996 : organelle organization and biogenesis. is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001003 name: aberrant response to stimulus def: "Deviation from the normal, usual, or expected events during the response to stimulus." [DDB:pg] comment: Child of GO:0050896 : response to stimulus. is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001004 name: obsolete aberrant cellular physiological process def: "OBSOLETE. Deviation from the normal, usual, or expected events during cellular physiological process." [DDB:pg] comment: Obsoleted because GO merged with cellular process. All children moved under DDPHENO:0001008 aberrant cellular process is_obsolete: true [Term] id: DDPHENO:0001005 name: aberrant cellular metabolic process def: "Deviation from the normal, usual, or expected events during cellular metabolism." [DDB:pg] comment: Child of GO:0044237: cellular metabolism. synonym: "aberrant cellular metabolism" EXACT [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001006 name: aberrant phagocytosis def: "Deviation from the normal, usual, or expected events during phagocytosis." [DDB:pg] comment: Child of GO:0006909 : phagocytosis. is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0001007 name: aberrant pinocytosis def: "Deviation from the normal, usual, or expected events during pinocytosis." [DDB:pg] comment: Child of GO:0006907 : pinocytosis. is_a: DDPHENO:0000090 ! aberrant endocytosis [Term] id: DDPHENO:0001008 name: aberrant cellular process def: "Deviation from the normal, usual, or expected events during cellular processes." [DDB:pg] comment: Child of GO:0009987 : cellular process. is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001009 name: aberrant localization def: "Deviation from the normal, usual, or expected events during localization." [DDB:pg] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001010 name: aberrant macrocyst formation alt_id: DDPHENO:0000476 def: "Deviation from the normal, usual, or expected events during sexual macrocyst formation." [DDB:pf] comment: Child of GO:0000747: conjugation with cellular fusion. synonym: "aberrant aggregation during macrocyst formation" NARROW [] synonym: "aberrant sexual macrocyst formation" EXACT [] synonym: "aberrant sexual reproduction" BROAD [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001011 name: obsolete decreased intracellular cAMP level def: "OBSOLETE. Reduction in extent, amount or degree of intracellular cAMP level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001012 name: aberrant stalk development def: "Deviation from the normal, usual, or expected events during stalk development." [DDB:pg] synonym: "aberrant sorocarp stalk development" EXACT [] synonym: "aberrant stalk formation" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001013 name: aberrant cell differentiation def: "Deviation from the normal, usual, or expected events during cell differentiation." [DDB:pg] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0001014 name: aberrant slug development def: "Deviation from the normal, usual, or expected events during slug development." [DDB:pg] synonym: "aberrant slug development involved in sorocarp development" EXACT [] synonym: "aberrant slug formation" RELATED [] synonym: "pseudoplasmodium development" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0001015 name: aberrant culmination def: "Deviation from the normal, usual, or expected events during culmination." [DDB:pg] synonym: "aberrant culmination involved in sorocarp development" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0001016 name: aberrant regulation of fruiting body formation def: "Deviation from the normal, usual, or expected events during the regulation of fruiting body formation." [DDB:pg] synonym: "aberrant regulation of sorocarp development" EXACT [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0001017 name: aberrant mound size def: "Deviation from the normal, usual, or expected events during the development of mound size." [DDB:pf] synonym: "aberrant aggregate size" EXACT [] synonym: "aberrant regulation of aggregation during fruiting body formation" RELATED [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001020 name: aberrant regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during the regulation of stalk cell differentiation." [DDB:pg] synonym: "aberrant regulation of sorocarp stalk cell differentiation" EXACT [] is_a: DDPHENO:0000546 ! aberrant stalk cell differentiation [Term] id: DDPHENO:0001021 name: aberrant negative regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during negative regulation of stalk cell differentiation." [DDB:pg] synonym: "aberrant negative regulation of sorocarp stalk cell differentiation" EXACT [] is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation [Term] id: DDPHENO:0001022 name: aberrant positive regulation of stalk cell differentiation def: "Deviation from the normal, usual, or expected events during positive regulation of stalk cell differentiation." [DDB:pg] synonym: "aberrant positive regulation of sorocarp stalk cell differentiation" EXACT [] is_a: DDPHENO:0001020 ! aberrant regulation of stalk cell differentiation [Term] id: DDPHENO:0001023 name: aberrant prestalk cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk cells." [DDB:pg] synonym: "aberrant pst cell differentiation" EXACT [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001024 name: aberrant prestalk O cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk O cells." [DDB:pf] synonym: "aberrant pstO cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0001025 name: aberrant prespore cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prespore cells." [DDB:pg] synonym: "aberrant psp cell differentiation" EXACT [] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001026 name: aberrant ion transport def: "Deviation from the normal, usual, or expected events during ion transport." [DDB:pg] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0001027 name: aberrant pseudopodium formation def: "Deviation from the normal, usual, or expected events during pseudopodium formation." [DDB:pg] synonym: "aberrant pseudopodium assembly" EXACT [] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001028 name: aberrant filopodium formation def: "Deviation from the normal, usual, or expected events during filopodium formation." [DDB:pg] synonym: "aberrant filopodium assembly" EXACT [] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001029 name: aberrant establishment or maintenance of cell polarity def: "Deviation from the normal, usual, or expected events during establishment and/or maintenance of cell polarity." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphogenesis [Term] id: DDPHENO:0001030 name: aberrant protein secretion alt_id: DDPHENO:0000186 def: "Deviation from the normal, usual, or expected events during protein secretion." [DDB:pg] synonym: "aberrant lysosomal traffic" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001031 name: aberrant response to abiotic stimulus def: "Deviation from the normal, usual, or expected events during the response to abiotic stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001032 name: aberrant response to biotic stimulus def: "Deviation from the normal, usual, or expected events during the response to biotic stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001033 name: aberrant macrocyst morphology def: "Deviation from the normal, usual, or expected morphology of the macrocyst." [DDB:pg] is_a: DDPHENO:0000236 ! aberrant cell morphogenesis [Term] id: DDPHENO:0001034 name: aberrant cellular response to stress def: "Deviation from the normal, usual, or expected events during the cellular response to stress." [DDB:pf] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001035 name: aberrant cellular response to heat def: "Deviation from the normal, usual, or expected events during the response to heat." [DDB:pg] synonym: "aberrant cellular response to heat shock" EXACT [] is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0001036 name: aberrant response to oxidative stress def: "Deviation from the normal, usual, or expected events during the response to oxidative stress." [DDB:pg] is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0001037 name: obsolete aberrant signal transduction during aggregation def: "OBSOLETE. Deviation from the normal, usual, or expected events during signal trnduction during aggregation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001038 name: aberrant extracellular cAMP signaling pathway alt_id: DDPHENO:0000419 alt_id: DDPHENO:0000468 alt_id: DDPHENO:0000469 def: "Deviation from the normal, usual, or expected events during extracellular cAMP signaling." [DDB:pf] comment: Merged with aberrant cAMP signaling during aggregation. PG 10-24-2006. synonym: "aberrant adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway" EXACT [] synonym: "aberrant cAMP signaling during aggregation" RELATED [] synonym: "merged_aggregation hypersensitive to caffeine" NARROW [] synonym: "merged_aggregation resistant to caffeine" NARROW [] synonym: "merged_impaired cAMP signaling in the presence of gossypol" NARROW [] is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001039 name: aberrant cellular response to starvation def: "Deviation from the normal, usual, or expected events during the cellular response to starvation." [DDB:pf] is_a: DDPHENO:0001034 ! aberrant cellular response to stress [Term] id: DDPHENO:0001040 name: obsolete aberrant response to drug def: "OBSOLETE. Deviation from the normal, usual, or expected events during response to drug." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001041 name: aberrant vacuole organization def: "Deviation from the normal, usual, or expected process of vacuole organization." [DDB:pf, DDB:pg] synonym: "aberrant vacuolar assembly" NARROW [] synonym: "aberrant vacuolation" RELATED [] synonym: "aberrant vacuole formation" EXACT [] is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001042 name: aberrant cellular component organization def: "Deviation from the normal, usual, or expected events during cellular component organization." [DDB:pf] synonym: "aberrant cellular component organization or biogenesis" EXACT [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001043 name: aberrant organelle organization def: "Deviation from the normal, usual, or expected events during organelle organization." [DDB:pg] synonym: "aberrant organelle organization and biogenesis" EXACT [] is_a: DDPHENO:0001042 ! aberrant cellular component organization [Term] id: DDPHENO:0001044 name: aberrant cell adhesion def: "Deviation from the normal, usual, or expected events during cell adhesion." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001045 name: obsolete aberrant response to DNA damaging agents def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to DNA damaging agents." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001046 name: aberrant spore germination def: "Deviation from the normal, usual, or expected events during release from spore dormancy." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001047 name: aberrant transport def: "Deviation from the normal, usual, or expected events during transport." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001048 name: aberrant cell projection biogenesis def: "Deviation from the normal, usual, or expected events during cell projection biogenesis." [DDB:pg] synonym: "aberrant cell projection assembly" EXACT [] is_a: DDPHENO:0001042 ! aberrant cellular component organization [Term] id: DDPHENO:0001049 name: aberrant bleb assembly def: "Deviation from the normal, usual, or expected events during bleb formation." [DDB:pf] synonym: "aberrant bleb formation" EXACT [] synonym: "aberrant cell blebbing" RELATED [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001050 name: abolished bleb assembly def: "Complete inability to form blebs." [DDB:pf] synonym: "abolished bleb formation" EXACT [] synonym: "abolished cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb assembly [Term] id: DDPHENO:0001051 name: obsolete abolished chemotaxis during aggregation def: "OBSOETE. Complete inability for chemotaxis during aggregation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001052 name: decreased bleb assembly def: "Reduction in extent, amount, or degree of bleb assembly." [DDB:pf] synonym: "decreased bleb formation" EXACT [] synonym: "decreased cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb assembly [Term] id: DDPHENO:0001053 name: increased bleb assembly def: "Increase in extent, amount, or degree of bleb assembly." [DDB:pf] synonym: "increased bleb formation" EXACT [] synonym: "increased cell blebbing" RELATED [] is_a: DDPHENO:0001049 ! aberrant bleb assembly [Term] id: DDPHENO:0001054 name: increased number of early culminant tips def: "Increase in extend, amount, or degree of the number of tips in early culminant." [DDB:pf] synonym: "increased number of tip-organizers of the early culminant" EXACT [] synonym: "multiple tips in early culminant" EXACT [] is_a: DDPHENO:0000036 ! increased number of tip-organizers [Term] id: DDPHENO:0001055 name: increased number of mound tips def: "Increase in extend, amount, or degree of the number of mound tips." [DDB:pf] synonym: "increased number of tip-organizers of the tipped mound" EXACT [] synonym: "multiple tips in mound" EXACT [] is_a: DDPHENO:0000036 ! increased number of tip-organizers [Term] id: DDPHENO:0001056 name: decreased actin filament polymerization def: "Reduction in extent, amount, or degree of F-actin polymerization." [DDB:pg] synonym: "decreased F-actin polymerization" EXACT [] is_a: DDPHENO:0001445 ! aberrant actin filament polymerization [Term] id: DDPHENO:0001057 name: abolished actin filament polymerization def: "Complete inability to polymerize actin into F-actin." [DDB:pg] synonym: "abolished F-actin polymerization" EXACT [] is_a: DDPHENO:0001445 ! aberrant actin filament polymerization [Term] id: DDPHENO:0001058 name: obsolete decreased protein kinase activation def: "OBSOLETE Reduction in extent, amount, or degree of activation of a protein kinase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001059 name: obsolete abolished chemotaxis to cAMP during aggregation def: "OBSOLETE. Complete inability for chemotaxis to cAMP during aggregation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001061 name: obsolete increased protein kinase activation def: "OBSOLETE Increase in extent, amount, or degree of activation of protein kinases." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001062 name: obsolete abolished protein kinase activation def: "OBSOLETE Complete inability for activation of protein kinases." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001063 name: obsolete abolished myosin light chain kinase activation def: "OBSOLETE. Complete inability for myosin light chain activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001064 name: obsolete decreased myosin light chain kinase activation def: "OBSOLETE. Reduction in extent, amount or degree of myosin light chain kinase activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001065 name: obsolete increased myosin light chain kinase activation def: "OBSOLETE. Increase in extent, amount, or degree of myosin light chain kinase activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001066 name: aberrant contractile vacuole morphology def: "Deviation from the normal, usual, or expected morphology of the vacuole." [DDB:pg] is_a: DDPHENO:0000233 ! aberrant contractile vacuole organization is_a: DDPHENO:0001002 ! aberrant organelle morphology [Term] id: DDPHENO:0001067 name: aberrant cellular hyperosmotic response def: "Deviation from the normal, usual, or expected events during cellular response to hyperosmotic stress." [DDB:pf] comment: GO:0071474. synonym: "aberrant cellular hypertonic response" EXACT [] synonym: "aberrant cellular response to hyperosmotic stress" EXACT [] synonym: "aberrant cellular response to hypertonic stress" EXACT [] is_a: DDPHENO:0000209 ! aberrant cellular response to osmotic stress [Term] id: DDPHENO:0001068 name: aberrant cellular hypotonic response def: "Deviation from the normal, usual, or expected events during cellular response to hypo-osmotic stress." [DDB:pf] comment: GO:0071476. For example, when Dictyostelium cells are placed into water, they suffer from hypotonic stress and their contractile vacuole system allows them to survive for some time. synonym: "aberrant cellular response to hypo-osmotic stress" EXACT [] synonym: "aberrant cellular response to hypotonic stress" EXACT [] is_a: DDPHENO:0000209 ! aberrant cellular response to osmotic stress [Term] id: DDPHENO:0001069 name: delayed cellular hyperosmotic response def: "Late onset or slower progression in the cellular response to hyperosmotic stress." [DDB:pf] synonym: "delayed cellular hypertonic response" EXACT [] synonym: "delayed cellular response to hyperosmotic stress" EXACT [] is_a: DDPHENO:0001067 ! aberrant cellular hyperosmotic response [Term] id: DDPHENO:0001070 name: precocious cellular hyperosmotic response def: "Early onset or faster progression in the response to cellular hyperosmotic stress." [DDB:pf] synonym: "precocious cellular hypertonic response" EXACT [] synonym: "precocious cellular response to hyperosmotic stress" EXACT [] is_a: DDPHENO:0001067 ! aberrant cellular hyperosmotic response [Term] id: DDPHENO:0001071 name: precocious cellular hypotonic response def: "Early onset or faster progression in the cellular response to hypo-osmotic stress." [DDB:pf] synonym: "precocious cellular response to hypo-osmotic stress" EXACT [] synonym: "precocious cellular response to hypotonic stress" EXACT [] is_a: DDPHENO:0001068 ! aberrant cellular hypotonic response [Term] id: DDPHENO:0001072 name: delayed cellular hypotonic response def: "Late onset or slower progression in the cellular response to hypo-osmotic stress." [DDB:pf] synonym: "delayed cellular response to hypo-osmotic stress" EXACT [] synonym: "delayed cellular response to hypotonic stress" EXACT [] is_a: DDPHENO:0001068 ! aberrant cellular hypotonic response [Term] id: DDPHENO:0001074 name: aberrant osmosensory signaling pathway def: "Deviation from the normal, usual, or expected events during the osmosensory signaling pathway." [DDB:pg] is_a: DDPHENO:0001067 ! aberrant cellular hyperosmotic response [Term] id: DDPHENO:0001075 name: decreased prestalk A cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk A cells." [DDB:pg] synonym: "decreased number of prestalk A cells" RELATED [] synonym: "decreased pstA cell differentiation" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation [Term] id: DDPHENO:0001076 name: abolished prestalk A cell differentiation def: "Complete inability for differentiation of prestalk A cells." [DDB:pg] synonym: "abolished pstA cell differentiation" EXACT [] is_a: DDPHENO:0000098 ! aberrant prestalk A cell differentiation is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation [Term] id: DDPHENO:0001077 name: aberrant slug migration def: "Deviation from the normal, usual, or expected events during slug migration." [DDB:kp] synonym: "aberrant migratory slug locomotion" EXACT [] is_a: DDPHENO:0001014 ! aberrant slug development [Term] id: DDPHENO:0001078 name: aberrant mitochondrion morphology def: "Deviation from the normal, usual, or expected morphology of the mitochondrion." [DDB:pg] synonym: "aberrant mitochondrial morphology" EXACT [] is_a: DDPHENO:0001002 ! aberrant organelle morphology is_a: DDPHENO:0001234 ! aberrant mitochondrion organization [Term] id: DDPHENO:0001079 name: obsolete decreased number of tubular mitochondria def: "OBSOLETE. Quantitative decrease in tubular mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001080 name: abolished aggregation def: "Complete inability for aggregation." [DDB:pg] synonym: "abolished aggregation during fruiting body development" EXACT [] synonym: "abolished aggregation involved in sorocarp development" EXACT [] synonym: "agg-" EXACT [] is_a: DDPHENO:0000483 ! aberrant aggregation [Term] id: DDPHENO:0001081 name: obsolete decreased number of spherical mitochondria def: "OBSOLETE. Quantitative decrease in spherical mitochondria." [DDB:pg] comment: In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular. is_obsolete: true [Term] id: DDPHENO:0001082 name: obsolete increased number of spherical mitochondria def: "OBSOLETE. Quantitative increase in spherical mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001083 name: obsolete decreased number of rod-shaped mitochondria def: "OBSOLETE. Quantitative decrease in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001084 name: aberrant vegetative growth def: "Deviation from the normal, usual, or expected events during vegetative growth." [DDB:pg] synonym: "aberrant asexual reproduction" EXACT [] synonym: "aberrant cell proliferation" RELATED [] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001085 name: obsolete increased number of rod-shaped mitochondria def: "OBSOLETE. Quantitative increase in rod-shaped mitochondria. In Dictyostelium, cells have mitochondria of three different shapes: spherical, rod-like or tubular." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001086 name: increased chemotaxis to cAMP def: "Increase in extent, amount, or degree of chemotaxis in response to cAMP." [DDB:pf] synonym: "increased positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000400 ! increased chemotaxis rate is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0001087 name: increased chemotaxis to folate def: "Increase in extent, amount, or degree of chemotaxis in response to folate." [DDB:pf] synonym: "increased chemotaxis to folic acid" EXACT [] synonym: "increased positive chemotaxis to folate" EXACT [] synonym: "increased positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000400 ! increased chemotaxis rate is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0001088 name: aberrant response to DIF-1 def: "Deviation from the normal, usual, or expected during the response to differentiation inducing factor 1." [DDB:pg] synonym: "aberrant response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0001032 ! aberrant response to biotic stimulus [Term] id: DDPHENO:0001090 name: decreased response to DIF-1 def: "Reduction in extent, amount, or degree of the response to DIF-1." [DDB:pg] synonym: "decreased response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF-1 [Term] id: DDPHENO:0001091 name: increased response to DIF-1 def: "Increase in extent, amount, or degree of response to DIF-1." [DDB:pg] synonym: "increased response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF-1 [Term] id: DDPHENO:0001092 name: abolished response to DIF-1 def: "Complete inability for response to DIF-1." [DDB:pg] synonym: "abolished response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0000693 ! abolished response to biotic stimulus is_a: DDPHENO:0001088 ! aberrant response to DIF-1 [Term] id: DDPHENO:0001093 name: delayed response to DIF-1 def: "Late onset or slower progression in the response to DIF-1." [DDB:pg] synonym: "delayed response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF-1 [Term] id: DDPHENO:0001094 name: precocious response to DIF-1 def: "Early onset or faster progression in the response to DIF-1." [DDB:pg] synonym: "precocious response to differentiation inducing factor 1" EXACT [] is_a: DDPHENO:0001088 ! aberrant response to DIF-1 [Term] id: DDPHENO:0001095 name: aberrant DIF-1 biosynthesis def: "Deviation from the normal, usual, or expected in the DIF-1 biosynthesis." [DDB:pf] synonym: "aberrant DIF-1 biosynthetic process" EXACT [] synonym: "aberrant DIF-1 production" RELATED [] synonym: "aberrant differentiation inducing factor 1 biosynthesis" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001097 name: decreased DIF-1 biosynthesis def: "Reduction in extent, amount, or degree for DIF-1 biosynthesis." [DDB:pf] synonym: "decreased DIF-1 biosynthetic process" EXACT [] synonym: "decreased DIF-1 production" RELATED [] synonym: "decreased differentiation inducing factor 1 biosynthesis" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis [Term] id: DDPHENO:0001098 name: increased DIF-1 biosynthesis def: "Increase in extent, amount, or degree for DIF-1 biosynthesis." [DDB:pf] synonym: "increased DIF-1 biosynthetic process" EXACT [] synonym: "increased DIF-1 production" RELATED [] synonym: "increased differentiation inducing factor 1 biosynthesis" EXACT [] is_a: DDPHENO:0001095 ! aberrant DIF-1 biosynthesis [Term] id: DDPHENO:0001099 name: obsolete delayed DIF production def: "OBSOLETE. Late onset or slower progression for DIF production." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001100 name: obsolete precocious DIF production def: "OBSOLETE. Complete inability for DIF production." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001101 name: abolished chemotaxis to cAMP def: "Complete inability for chemotaxis in response to cAMP." [DDB:pf] synonym: "abolished positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0000466 ! abolished positive chemotaxis is_a: DDPHENO:0001167 ! aberrant chemotaxis to cAMP [Term] id: DDPHENO:0001102 name: abolished chemotaxis to folate def: "Complete inability for chemotaxis in response to folate." [DDB:pf] synonym: "abolished chemotaxis to folic acid" EXACT [DDB:kp] synonym: "abolished positive chemotaxis to folate" RELATED [] synonym: "abolished positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0000466 ! abolished positive chemotaxis is_a: DDPHENO:0001168 ! aberrant chemotaxis to folate [Term] id: DDPHENO:0001103 name: decreased culmination def: "Reduction in extent, amount, or degree of culminants, resulting in fewer fruiting bodies." [DDB:pf] synonym: "decreased culmination involved in sorocarp development" EXACT [] synonym: "decreased number of fruiting bodies" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001104 name: increased culmination def: "Increase in extent, amount, or degree of culminants, resulting in more fruiting bodies." [DDB:pf] synonym: "increased culmination involved in sorocarp development" EXACT [] synonym: "increased number of fruiting bodies" RELATED [] is_a: DDPHENO:0001015 ! aberrant culmination [Term] id: DDPHENO:0001105 name: aberrant catalytic activity def: "Deviation from the normal, usual, or expected activity of a catalyst." [DDB:pf] synonym: "aberrant enzyme activity" NARROW [DDB:kp] is_a: DDPHENO:0001171 ! aberrant molecular function [Term] id: DDPHENO:0001106 name: decreased lysosomal protein degradation def: "Reduction in extent, amount, or degree of lysosomal protein degradation." [DDB:pf] synonym: "decreased lysosomal enzyme activity" RELATED [] synonym: "decreased lysosomal protein catabolic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001107 name: increased lysosomal protein degradation def: "Increase in extent, amount, or degree of lysosomal protein degradation." [DDB:pf] synonym: "increased lysosomal enzyme activity" EXACT [] synonym: "increased lysosomal protein catabolic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001108 name: aberrant response to lithium def: "Deviation from the normal, usual, or expected events during the response to lithium." [DDB:pf] synonym: "aberrant response to lithium ion" EXACT [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0001109 name: increased resistance to valproic acid def: "Deviation from the normal, usual, or expected events during the response to valproic acid." [DDB:pf] synonym: "aberrant response to valproic acid" RELATED [] synonym: "aberrant response to VPA" RELATED [] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0001110 name: aberrant exocytosis def: "Deviation from the normal, usual, or expected events during exocytosis." [DDB:pf] is_a: DDPHENO:0001047 ! aberrant transport [Term] id: DDPHENO:0001111 name: decreased exocytosis def: "Reduction in extent, amount, or degree of exocytosis." [DDB:pf] is_a: DDPHENO:0001110 ! aberrant exocytosis [Term] id: DDPHENO:0001112 name: increased exocytosis def: "Increase in extent, amount, or degree of exocytosis." [DDB:pf] is_a: DDPHENO:0001110 ! aberrant exocytosis [Term] id: DDPHENO:0001113 name: aberrant gene expression alt_id: DDPHENO:0001000 alt_id: DDPHENO:0001089 def: "Deviation from the normal, usual, or expected expression of genes." [DDB:kp] synonym: "aberrant expression of post aggregation-specific genes" NARROW [] synonym: "merged_aberrant expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_aberrant expression of post-aggregative genes" NARROW [DDB:kp] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001114 name: abolished gene expression alt_id: DDPHENO:0000299 alt_id: DDPHENO:0000515 def: "Complete inability for expression of genes." [DDB:kp] synonym: "merged_abolished expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_abolished expression of prespore genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001115 name: delayed gene expression alt_id: DDPHENO:0000179 alt_id: DDPHENO:0000268 alt_id: DDPHENO:0000470 alt_id: DDPHENO:0000485 def: "Late onset or slower progression in the expression of genes." [DDB:kp] synonym: "merged_delayed expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_delayed expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_delayed expression of prespore genes" NARROW [DDB:kp] synonym: "merged_delayed expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001116 name: precocious gene expression alt_id: DDPHENO:0000180 alt_id: DDPHENO:0000217 alt_id: DDPHENO:0000218 alt_id: DDPHENO:0001073 def: "Early onset or faster progression in the expression of genes." [DDB:kp] synonym: "merged_precocious expression of aggregation genes" NARROW [DDB:kp] synonym: "merged_precocious expression of post-aggregative genes" NARROW [DDB:kp] synonym: "merged_precocious expression of prespore genes" NARROW [DDB:kp] synonym: "merged_precocious expression of prestalk genes" NARROW [DDB:kp] is_a: DDPHENO:0001113 ! aberrant gene expression [Term] id: DDPHENO:0001117 name: obsolete mislocalized gene expression alt_id: DDPHENO:0000182 alt_id: DDPHENO:0000219 def: "OBSOLETE. Gene expression occurring in an abnormal position or in an unusual manner or form." [DDB:kp] is_obsolete: true [Term] id: DDPHENO:0001118 name: aberrant signal transduction def: "Deviation from the normal, usual, or expected events during signal transduction." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001119 name: obsolete aberrant regulation of protein kinase activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the regulation of protein kinase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001120 name: obsolete abolished protein kinase B activation def: "OBSOLETE. Complete inability for protein kinase B activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001121 name: aberrant taxis def: "Deviation from the normal, usual, or expected events during the response to an external stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001122 name: aberrant chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response to a chemical concentration gradient." [DD:pg] is_a: DDPHENO:0000040 ! aberrant response to chemical is_a: DDPHENO:0000264 ! aberrant cell motility is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001123 name: increased phototaxis def: "Increase in extent, amount, or degree of phototaxis." [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0001124 name: increased thermotaxis def: "Increase in extent, amount, or degree of thermotaxis." [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001129 ! increased taxis [Term] id: DDPHENO:0001125 name: abolished phototaxis def: "Complete inability for phototaxis." [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001131 ! abolished taxis [Term] id: DDPHENO:0001126 name: abolished thermotaxis def: "Complete inability for thermotaxis." [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001131 ! abolished taxis [Term] id: DDPHENO:0001127 name: decreased phototaxis def: "Reduction in extent, amount, or degree of phototaxis." [DDB:pg] is_a: DDPHENO:0000222 ! aberrant phototaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0001128 name: decreased thermotaxis def: "Reduction in extent, amount, or degree of thermotaxis." [DDB:pg] is_a: DDPHENO:0000223 ! aberrant thermotaxis is_a: DDPHENO:0001130 ! decreased taxis [Term] id: DDPHENO:0001129 name: increased taxis def: "Increase in extent, amount, or degree of the response to an external stimulus." [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001130 name: decreased taxis def: "Reduction in extent, amount, or degree of the response to external stimulus." [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001131 name: abolished taxis def: "Complete inability to respond to an external stimulus." [DDB:pg] is_a: DDPHENO:0001121 ! aberrant taxis [Term] id: DDPHENO:0001132 name: obsolete decreased activation of adenylate cyclase activity def: "OBSOLETE Reduction in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001133 name: obsolete abolished activation of adenylate cyclase activity def: "OBSOLETE Complete inability to activate adenylate cyclase upon stimulus." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001134 name: obsolete increased activation of adenylate cyclase activity def: "OBSOLETE Increase in extent, amount, or degree of activation of adenylate cyclase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001135 name: obsolete abolished chemoattractant-mediated F-actin polymerization def: "OBSOLETE. Complete inability for chemoattractant-mediated F-actin polymerization." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001136 name: obsolete increased chemoattractant-mediated F-actin polymerization def: "OBSOLETE. Increase in extent, amount, or degree of chemoattractant-mediated F-actin polymerization." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001137 name: obsolete aberrant regulation of GTPase activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the regulation of the activity of a GTPase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001138 name: obsolete decreased positive regulation of GTPase activity def: "OBSOLETE Reduction in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001139 name: obsolete increased positive regulation of GTPase activity def: "IOBSOLETE Increase in extent, amount, or degree of positive regulation of GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001140 name: obsolete aberrant regulation of Ras GTPase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Ras GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001141 name: obsolete aberrant regulation of Rac GTPase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rac GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001142 name: obsolete aberrant regulation of Rab GTPase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rab GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001143 name: obsolete aberrant regulation of Ran GTPase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Ran GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001144 name: obsolete aberrant regulation of Rap GTPase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of Rap GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001145 name: obsolete decreased positive regulation of Rab GTPase activity def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rab GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001146 name: obsolete increased positive regulation of Rab GTPase activity def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rab GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001147 name: obsolete decreased positive regulation of Rac GTPase activity def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rac GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001148 name: obsolete increased positive regulation of Rac GTPase activity def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rac GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001149 name: obsolete decreased positive regulation of Ran GTPase activity def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Ran GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001150 name: obsolete increased positive regulation of Ran GTPase activity def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Ran GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001151 name: obsolete decreased positive regulation of Rap GTPase activity def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Rap GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001152 name: obsolete increased positive regulation of Rap GTPase activity def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Rap GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001153 name: obsolete increased positive regulation of Ras GTPase activity def: "OBSOLETE. Increase in extent, amount, or degree of positive regulation of Ras GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001154 name: obsolete decreased positive regulation of Ras GTPase activity def: "OBSOLETE. Reduction in extent, amount or accumulation of positive regulation of Ras GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001155 name: aberrant macromolecule biosynthesis def: "Deviation from the normal, usual, or expected events during macromolecule biosynthesis." [DDB:pg] synonym: "aberrant macromolecule biosynthetic process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001156 name: aberrant cellulose biosynthesis def: "Deviation from the normal, usual, or expected events during cellulose biosynthesis." [DDB:pg] synonym: "aberrant cellulose biosynthetic process" EXACT [] is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis [Term] id: DDPHENO:0001157 name: abolished cellulose biosynthesis def: "Complete inability for cellulose biosynthesis." [DDB:pg] synonym: "abolished cellulose biosynthetic process" EXACT [] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001158 name: increased cellulose biosynthesis def: "Increase in extent, amount, or degree of cellulose biosynthesis." [DDB:pg] synonym: "increased cellulose biosynthetic process" EXACT [] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001159 name: decreased cellulose biosynthesis def: "Reduction in extent, amount, or degree of cellulose biosynthesis." [DDB:pg] synonym: "decreased cellulose biosynthetic process" EXACT [] is_a: DDPHENO:0001156 ! aberrant cellulose biosynthesis [Term] id: DDPHENO:0001160 name: abolished superoxide generation def: "Complete inability for superoxide generation." [DDB:pf] synonym: "abolished superoxide anion generation" EXACT [] synonym: "abolished superoxide production" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001161 name: decreased superoxide generation def: "Reduction in extent, amount, or degree of superoxide generation." [DDB:pf] synonym: "decreased superoxide anion generation" EXACT [] synonym: "decreased superoxide production" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001162 name: increased superoxide generation def: "Increase in amount or generation of superoxide." [DDB:pf] synonym: "increased superoxide anion generation" EXACT [] synonym: "increased superoxide production" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001163 name: aberrant prestalk B cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk B cells." [DDB:pg] synonym: "aberrant pstB cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation [Term] id: DDPHENO:0001164 name: abolished prestalk B cell differentiation def: "Complete inability for differentiation of prestalk B cells." [DDB:pg] synonym: "abolished pstB cell differentiation" EXACT [] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001165 name: decreased prestalk B cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk B cells." [DDB:pg] synonym: "decreased number of prestalk B cells" RELATED [] synonym: "decreased pstB cell differentiation" EXACT [] is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001166 name: increased prestalk B cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk B cells." [DDB:pg] synonym: "increased number of prestalk B cells" RELATED [] synonym: "increased pstB cell differentiation" EXACT [] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation is_a: DDPHENO:0001163 ! aberrant prestalk B cell differentiation [Term] id: DDPHENO:0001167 name: aberrant chemotaxis to cAMP def: "Deviation from the normal, usual, or expected events during the locomotory response to cAMP." [DDB:kp] synonym: "aberrant positive chemotaxis to cAMP" EXACT [] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis [Term] id: DDPHENO:0001168 name: aberrant chemotaxis to folate def: "Deviation from the normal, usual, or expected events during the locomotory response to folate (folic acid)." [DDB:kp] synonym: "aberrant chemotaxis to folic acid" EXACT [DDB:kp] synonym: "aberrant positive chemotaxis to folate" EXACT [] synonym: "aberrant positive chemotaxis to folic acid" EXACT [] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis [Term] id: DDPHENO:0001169 name: delayed cytokinesis def: "Late onset or slower progression through cytokinesis." [DDB:pf] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0001170 name: aberrant mitotic actomyosin contractile ring contraction def: "Deviation from the normal, usual, or expected events during contractile ring contraction during mitotic cytokinesis." [DDB:pf] synonym: "aberrant cytokinesis, contractile ring contraction" EXACT [] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0001171 name: aberrant molecular function def: "Deviation from normal, usual, or expected molecular function." [DDB:kp] is_a: DDPHENO:0010000 ! Dicty Phenotypes [Term] id: DDPHENO:0001172 name: increased guanyl-nucleotide exchange factor activity def: "Increase in extent, amount, or degree of guanyl-nucleotide exchange factor activity." [DDB:pf] synonym: "increased GEF activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001173 name: obsolete aberrant aspidocyte differentiation def: "OBSOLETE. Deviation from the normal, usual, or expected events during aspidocyte differentiation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001174 name: increased cell differentiation def: "Increase in extent, amount, or degree of cell differentiation." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001175 name: decreased cell differentiation def: "Decrease in extent, amount, or degree of cell differentiation." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001176 name: abolished cell differentiation def: "Complete inability for cell differentiation." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001177 name: decreased pseudopodium formation def: "Decrease in extent, amount, or degree of formation of pseudopods." [DDB:pg] synonym: "decreased pseudopod extension" RELATED [] synonym: "decreased pseudopodium assembly" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0001178 name: decreased pseudopodium size def: "Reduction in relative or proportionate dimensions of the pseudopodium." [DDB:pf] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0001179 name: decreased actin filament polymerization at leading edge def: "Reduction in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell." [DDB:pf] synonym: "decreased F-actin polymerization at leading edge" EXACT [] is_a: DDPHENO:0001056 ! decreased actin filament polymerization [Term] id: DDPHENO:0001180 name: increased actin filament polymerization at leading edge def: "Increase in extent, amount, or degree of F-actin polymerization in the area closest to the direction of movement in a motile cell." [DDB:pf] synonym: "increased F-actin polymerization at leading edge" EXACT [] is_a: DDPHENO:0000459 ! increased actin filament polymerization [Term] id: DDPHENO:0001181 name: delayed pseudopodium formation def: "Late onset or slower progression during pseudopodium formation." [DDB:pf] synonym: "delayed pseudopod extension" RELATED [] synonym: "delayed pseudopodium assembly" EXACT [] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0001182 name: decreased spore size def: "Decrease in relative or proportionate dimensions of the spore." [DDB:pg] synonym: "small spores" RELATED [] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0001183 name: increased spore size def: "Increase in relative or proportionate dimensions of the spore." [DDB:pg] synonym: "large spores" RELATED [] is_a: DDPHENO:0000163 ! aberrant spore morphology [Term] id: DDPHENO:0001184 name: decreased myo-inositol level def: "Decrease in amount or accumulation of intracellular myo-inositol." [DDB:pg] synonym: "decreased cytosolic myo-inositol level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001185 name: increased myo-inositol level def: "Increase in amount or accumulation of intracellular myo-inositol." [DDB:pg] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001186 name: increased 2,3-bisphosphoglycerate level def: "Increase in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg] synonym: "increased 2,3-BPG" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001187 name: decreased 2,3-bisphosphoglycerate level def: "Reduction in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pg] synonym: "decreased 2,3-BPG" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001188 name: abolished macroautophagy def: "Complete inability for macroautophagy." [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001189 name: decreased macroautophagy def: "Reduction in extent, amount, or degree of macroautophagy." [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001190 name: increased macroautophagy def: "Increase in extent, amount, or degree of macroautophagy." [DDB:pf] is_a: DDPHENO:0000212 ! aberrant macroautophagy [Term] id: DDPHENO:0001191 name: increased number of autophagosomes def: "Quantitative increase in autophagosomes." [DDB:pf] synonym: "increased number of autophagic vacuoles" EXACT [] is_a: DDPHENO:0001041 ! aberrant vacuole organization [Term] id: DDPHENO:0001192 name: decreased number of autophagosomes def: "Quantitative reduction in autophagosomes." [DDB:pf] synonym: "decreased number of autophagic vacuoles" EXACT [] is_a: DDPHENO:0001279 ! decreased autophagic vacuole organization [Term] id: DDPHENO:0001193 name: obsolete aberrant infection rate by a microorganism def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001194 name: obsolete increased infection rate by a microorganism def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001195 name: obsolete decreased infection rate by a microorganism def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0001196 name: obsolete decreased infection rate by Mycobacterium avium def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0001197 name: obsolete decreased infection rate by Cryptococcus neoformans def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0001198 name: obsolete increased infection rate by Cryptococcus neoformans def: "OBSOLETE. Was not defined before obsoletion." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001199 name: obsolete decreased actin-dependent ATPase activity def: "OBSOLETE. Reduction in extent, amount, or degree of decreased actin-dependent ATPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001200 name: obsolete increased actin-dependent ATPase activity def: "OBSOLETE. Increase in extent, amount, or degree of increased actin-dependent ATPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001201 name: decreased actin filament sliding def: "Reduction in amount or accumulation of actin filament sliding." [DDB:pf] synonym: "decreased actin-myosin filament sliding" EXACT [] synonym: "decreased F-actin sliding" EXACT [] is_a: DDPHENO:0000151 ! aberrant actin filament organization [Term] id: DDPHENO:0001202 name: increased actin filament sliding def: "Increased in extent, amount, or degree of F-actin filament sliding." [DDB:pf] synonym: "increased actin-myosin filament sliding" EXACT [] synonym: "increased F-actin sliding" EXACT [] is_a: DDPHENO:0000151 ! aberrant actin filament organization [Term] id: DDPHENO:0001203 name: aberrant response to nutrient def: "Deviation from the normal, usual, or expected events during the response to nutrients." [DDB:pf] is_a: DDPHENO:0000040 ! aberrant response to chemical [Term] id: DDPHENO:0001204 name: increased endosome size def: "Increase in relative or proportionate dimensions of the endosome." [DDB:pg] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001205 name: decreased endosome size def: "Decrease in relative or proportionate dimensions of the endosome." [DDB:pg] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001206 name: aberrant lysosome morphology def: "Deviation from the normal, usual, or expected morphology of the lysosome." [DDB:pf] is_a: DDPHENO:0000230 ! aberrant endosome morphology [Term] id: DDPHENO:0001207 name: decreased lysosome size def: "Decrease in relative or proportionate dimensions of the lysosome." [DDB:pg] is_a: DDPHENO:0001205 ! decreased endosome size is_a: DDPHENO:0001206 ! aberrant lysosome morphology [Term] id: DDPHENO:0001208 name: increased lysosome size def: "Increase in relative or proportionate dimensions of the lysosome." [DDB:pg] is_a: DDPHENO:0001204 ! increased endosome size is_a: DDPHENO:0001206 ! aberrant lysosome morphology [Term] id: DDPHENO:0001209 name: aberrant translation def: "Deviation from the normal, usual, or expected events during translation." [DDB:pg] synonym: "aberrant protein biosynthesis" EXACT [] synonym: "aberrant protein synthesis" EXACT [] synonym: "aberrant protein translation" EXACT [] is_a: DDPHENO:0001155 ! aberrant macromolecule biosynthesis [Term] id: DDPHENO:0001210 name: abolished translation def: "Complete inability for translation." [DDB:pg] synonym: "abolished protein biosynthesis" EXACT [] synonym: "abolished protein synthesis" EXACT [] synonym: "abolished protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001211 name: decreased translation def: "Reduction in extent, amount, or degree of translation." [DDB:pg] synonym: "decreased protein biosynthesis" EXACT [] synonym: "decreased protein synthesis" EXACT [] synonym: "decreased protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001212 name: increased translation def: "Increase in extent, amount, or degree of translation." [DDB:pg] synonym: "increased protein biosynthesis" EXACT [] synonym: "increased protein synthesis" EXACT [] synonym: "increased protein translation" EXACT [] is_a: DDPHENO:0001209 ! aberrant translation [Term] id: DDPHENO:0001213 name: decreased calcium-dependent cell-cell adhesion def: "Reduction in extent, amount, or degree of calcium-dependent cell-cell adhesion." [DDB:pf] synonym: "decreased calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "decreased EDTA-sensitive cell-cell adhesion" RELATED [] is_a: DDPHENO:0000138 ! decreased cell-cell adhesion [Term] id: DDPHENO:0001214 name: decreased calcium-independent cell-cell adhesion def: "Reduction in extent, amount, or degree of calcium-independent cell-cell adhesion." [DDB:pf] synonym: "decreased calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "decreased EDTA-resistant cell-cell adhesion" RELATED [] is_a: DDPHENO:0000138 ! decreased cell-cell adhesion [Term] id: DDPHENO:0001215 name: increased calcium-dependent cell-cell adhesion def: "Increase in extent, amount, or degree of calcium-dependent cell-cell adhesion." [DDB:pf] synonym: "increased calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "increased EDTA-sensitive cell-cell adhesion" RELATED [] is_a: DDPHENO:0000109 ! increased cell-cell adhesion [Term] id: DDPHENO:0001216 name: increased calcium-independent cell-cell adhesion def: "Increase in extent, amount, or degree of calcium-independent cell-cell adhesion." [DDB:pf] synonym: "increased calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "increased EDTA-resistant cell-cell adhesion" RELATED [] is_a: DDPHENO:0000109 ! increased cell-cell adhesion [Term] id: DDPHENO:0001217 name: aberrant cellular localization def: "Deviation from the normal, usual, or expected events during localization within the cell." [DDB:pf] comment: Use for mutated gene products that do not localize to their typical cellular compartment compared to the wild type gene product. is_a: DDPHENO:0001009 ! aberrant localization [Term] id: DDPHENO:0001218 name: aberrant organelle localization def: "Deviation from the normal, usual, or expected localization of an organelle within the cell." [DDB:pf] is_a: DDPHENO:0001217 ! aberrant cellular localization [Term] id: DDPHENO:0001219 name: aberrant Golgi localization def: "Deviation from the normal, usual, or expected localization of the Golgi apparatus." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001220 name: aberrant nucleus localization def: "Deviation from the normal, usual, or expected localization of the nucleus." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001221 name: aberrant centrosome localization def: "Deviation from the normal, usual, or expected localization of the centrosome." [DDB:pg] is_a: DDPHENO:0001218 ! aberrant organelle localization [Term] id: DDPHENO:0001222 name: aberrant phagolysosome formation def: "Deviation from the normal, usual, or expected events during phagolysosome formation." [DDB:pf] synonym: "aberrant late phagosome formation" RELATED [] synonym: "aberrant phagolysosome assembly" EXACT [] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001223 name: decreased phagolysosome formation def: "Reduction in extent, amount, or degree of phagolysosome formation." [DDB:pf] synonym: "decreased late phagosome formation" RELATED [] synonym: "decreased phagolysosome assembly" EXACT [] is_a: DDPHENO:0001222 ! aberrant phagolysosome formation [Term] id: DDPHENO:0001224 name: aberrant positive chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response guided by increasing chemical concentration gradient." [DDB:pg] is_a: DDPHENO:0001122 ! aberrant chemotaxis [Term] id: DDPHENO:0001225 name: aberrant negative chemotaxis def: "Deviation from the normal, usual, or expected events during the locomotory response towards a decreasing chemical concentration." [DDB:pf] synonym: "aberrant chemorepulsion" EXACT [] is_a: DDPHENO:0001122 ! aberrant chemotaxis [Term] id: DDPHENO:0001226 name: aberrant cellular response to extracellular stimulus def: "Deviation from the normal, usual, or expected during the cellular response to extracellular stimulus." [DDB:pg] is_a: DDPHENO:0001003 ! aberrant response to stimulus [Term] id: DDPHENO:0001227 name: obsolete aberrant response to prestarvation factor def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001228 name: obsolete aberrant detection of prestarvation factor def: "OBSOLETE. Deviation from the normal, usual, or expected events during the detection of prestarvation factor (PSF) found in conditioned media (CM)." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001229 name: decreased 3',5'-cyclic-AMP phosphodiesterase activity def: "Reduction in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pf] synonym: "decreased cAMP-specific phosphodiesterase activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001230 name: decreased 3',5'-cyclic-GMP phosphodiesterase activity def: "Reduction in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pf] synonym: "decreased cGMP-specific phosphodiesterase activity" RELATED [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001231 name: abolished protein secretion def: "Complete inability for protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion [Term] id: DDPHENO:0001232 name: increased protein secretion def: "Increase in extent, amount, or degree of protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001233 name: decreased protein secretion def: "Reduction in extent, amount, or degree of protein secretion." [DDB:pf] is_a: DDPHENO:0001030 ! aberrant protein secretion is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001234 name: aberrant mitochondrion organization def: "Deviation from the normal, usual, or expected events during mitochondrion organization." [DDB:pf] synonym: "aberrant mitochondrion organization and biogenesis" RELATED [] is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001235 name: decreased ATP level def: "Decrease in amount or accumulation of cytosolic ATP." [DDB:pf] synonym: "decreased cytosolic ATP level" EXACT [] synonym: "decreased intracellular ATP" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001236 name: increased ATP level def: "Increase in amount or accumulation of cytosolic ATP." [DDB:pf] synonym: "increased cytosolic ATP level" EXACT [] synonym: "increased intracellular ATP level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001237 name: aberrant lysosome organization def: "Deviation from the normal, usual, or expected events during lysosome organization and biogenesis." [DDB:pf] synonym: "aberrant lysosome maturation" NARROW [] synonym: "aberrant lysosome organization and biogenesis" EXACT [] is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001238 name: aberrant post-lysosomal vacuole exocytosis def: "Deviation from the normal, usual, or expected events during post-lysosomal vacuole exocytosis." [DDB:pf] synonym: "aberrant postlysosome exocytosis" EXACT [] is_a: DDPHENO:0001237 ! aberrant lysosome organization [Term] id: DDPHENO:0001239 name: abolished cell motility def: "Complete inability for cell motility." [DDB:pg] is_a: DDPHENO:0000264 ! aberrant cell motility [Term] id: DDPHENO:0001240 name: obsolete decreased CRAC localization to the plasma membrane def: "OBSOLETE. Reduction in extent, amount or degree of CRAC localization to the plasma membrane." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001241 name: aberrant protein level def: "Deviation from the normal, usual, or expected level of proteins." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001242 name: decreased protein level def: "Reduction in extent, amount, or degree of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001243 name: increased protein level def: "Increase in extent, amount, or degree of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001244 name: abolished protein level def: "Complete elimination of protein expression." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level [Term] id: DDPHENO:0001245 name: aberrant oscillatory cAMP signaling def: "Deviation from the normal, usual, or expected events during cAMP signal oscillations in early development." [DDB:pf] synonym: "aberrant cAMP relay" EXACT [] synonym: "aberrant cAMP-induced cAMP pulse" EXACT [] is_a: DDPHENO:0001038 ! aberrant extracellular cAMP signaling pathway [Term] id: DDPHENO:0001246 name: abolished oscillatory cAMP signaling def: "Complete inability for oscillatory cAMP signaling during early development." [DDB:pf] synonym: "abolished cAMP relay" EXACT [] synonym: "abolished cAMP-induced cAMP pulse" EXACT [] is_a: DDPHENO:0001245 ! aberrant oscillatory cAMP signaling [Term] id: DDPHENO:0001247 name: obsolete aberrant protein methylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during protein methylation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001248 name: obsolete abolished protein methylation def: "OBSOLETE Complete inability for protein methylation." [DDB:pf] synonym: "abolished protein amino acid methylation" EXACT [] is_obsolete: true [Term] id: DDPHENO:0001249 name: obsolete abolished C-terminal protein methylation def: "OBSOLETE Complete inability for C-terminal protein methylation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001250 name: abolished establishment of cell polarity def: "Complete inability to establish cell polarity." [DDB:pf] synonym: "abolished cell polarity" EXACT [] is_a: DDPHENO:0001029 ! aberrant establishment or maintenance of cell polarity [Term] id: DDPHENO:0001251 name: obsolete increased protein kinase B activation def: "OBSOLETE. Was not defined before obsoletion." [] is_obsolete: true [Term] id: DDPHENO:0001252 name: obsolete abolished MAP kinase activation def: "OBSOLETE. Complete inability for MAP activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001253 name: obsolete decreased MAP kinase activation def: "OBSOLETE. Reduction in extent, amount or degree of MAP kinase activation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001254 name: obsolete increased MAP kinase activation def: "OBSOLETE. Increase in extent, amount, or degree of activation of a MAP kinase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001255 name: aberrant binding def: "Deviation from the normal, usual, or expected binding." [DDB:pg] is_a: DDPHENO:0001171 ! aberrant molecular function [Term] id: DDPHENO:0001256 name: increased catalytic activity def: "Increase in extent, amount, or degree of catalysis by an enzyme." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001257 name: decreased catalytic activity def: "Reduction in extent, amount, or degree of catalysis by an enzyme." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001259 name: obsolete decreased binding def: "OBSOLETE. Reduction in extent, amount or degree of molecule binding." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001260 name: increased cAMP binding def: "Increased in extent, amount, or degree of binding to cAMP." [DDB:pg] synonym: "increased 3',5'-cyclic-AMP binding" EXACT [] is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding [Term] id: DDPHENO:0001261 name: decreased cAMP binding def: "A reduction in extent, amount, or degree of binding to cAMP." [DDB:pg] synonym: "decreased 3',5'-cyclic-AMP binding" EXACT [] is_a: DDPHENO:0000324 ! aberrant cyclic nucleotide binding is_a: DDPHENO:0000329 ! decreased small molecule binding [Term] id: DDPHENO:0001262 name: aberrant adaptation of signaling pathway def: "Deviation from the normal, usual, or expected events during the adaptation of a signaling pathway." [DDB:pg] is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001263 name: aberrant autophagic cell death def: "Deviation from the normal, usual, or expected events during autophagic cell death." [DDB:pf] is_a: DDPHENO:0000770 ! aberrant programmed cell death [Term] id: DDPHENO:0001264 name: abolished autophagic cell death def: "Complete inability for autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001265 name: increased autophagic cell death def: "Increase in extent, amount, or degree of autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001266 name: decreased autophagic cell death def: "Reduction in extent, amount, or degree of autophagic cell death." [DDB:pf] is_a: DDPHENO:0001263 ! aberrant autophagic cell death [Term] id: DDPHENO:0001267 name: aberrant cell death def: "Deviation from the normal, usual, or expected events during regular cell death." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001268 name: obsolete aberrant non-apoptotic programmed cell death def: "OBSOLETE. Deviation from the normal, usual, or expected events during non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001269 name: obsolete abolished non-apoptotic programmed cell death def: "OBSOLETE. Complete inability for non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001270 name: obsolete increased non-apoptotic programmed cell death def: "OBSOLETE. Increase in extent, amount, or degree of non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001271 name: obsolete decreased non-apoptotic programmed cell death def: "OBSOLETE. Reduction in extent, amount or degree of non-apoptotic programmed cell death." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001272 name: decreased pseudopodium retraction def: "Reduction in extent, amount, or degree of pseudopodium retraction." [DDB:pf] is_a: DDPHENO:0001027 ! aberrant pseudopodium formation [Term] id: DDPHENO:0001273 name: decreased uropod retraction def: "Reduction in extent, amount, or degree of uropod retraction." [DDB:pf] is_a: DDPHENO:0001048 ! aberrant cell projection biogenesis [Term] id: DDPHENO:0001274 name: abolished phagocytosis def: "Complete inability for phagocytosis." [DDB:pf] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001275 name: aberrant engulfment during phagocytosis def: "Deviation from the normal, usual, or expected events during engulfment of attached, recognized, external material." [DDB:pf] synonym: "aberrant phagocytosis, engulfment" EXACT [] synonym: "aberrant phagosome formation" RELATED [] is_a: DDPHENO:0001006 ! aberrant phagocytosis [Term] id: DDPHENO:0001276 name: abolished engulfment during phagocytosis def: "Complete inability of engulfment of attached, recognized, external material." [DDB:pf] synonym: "abolished phagocytosis, engulfment" EXACT [] synonym: "abolished phagosome formation" RELATED [] is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis [Term] id: DDPHENO:0001277 name: decreased engulfment during phagocytosis def: "Reduction in extent, amount, or degree of engulfment of attached, recognized, external material." [DDB:pf] synonym: "decreased phagocytosis, engulfment" EXACT [] synonym: "decreased phagosome formation" RELATED [] is_a: DDPHENO:0001275 ! aberrant engulfment during phagocytosis [Term] id: DDPHENO:0001278 name: obsolete aberrant vacuolation def: "OBSOLETE. Deviation from the normal, usual, or expected events during vacuolation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001279 name: decreased autophagic vacuole organization def: "Reduction in extent, amount, or degree of autophagic vacuole formation." [DDB:pf] synonym: "decreased autophagic vacuole formation" EXACT [] synonym: "decreased autophagosome organization" EXACT [] is_a: DDPHENO:0001041 ! aberrant vacuole organization [Term] id: DDPHENO:0001280 name: increased 3',5'-cyclic-AMP phosphodiesterase activity def: "Increase in extent, amount, or degree of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg] synonym: "increased cAMP-specific phosphodiesterase activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001281 name: increased 3',5'-cyclic-GMP phosphodiesterase activity def: "Increase in extent, amount, or degree of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg] synonym: "increased cGMP-specific phosphodiesterase activity>" RELATED [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001282 name: increased adenylate cyclase activity def: "Increase in extent, amount, or degree of adenylate cyclase activity." [DDB:pg] synonym: "increased ACA activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001283 name: obsolete decreased protein kinase A activity def: "OBSOLETE. Reduction in extent, amount or degree of protein kinase A activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001284 name: decreased guanyl-nucleotide exchange factor activity def: "Reduction in extent, amount, or degree of guanyl-nucleotide exchange factor activity." [DDB:pf] synonym: "decreased GEF activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001285 name: decreased adenylate cyclase activity def: "Reduction in extent, amount, or degree of adenylate cyclase activity." [DDB:pg] synonym: "decreased ACA activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001286 name: obsolete increased glycogen synthase kinase 3 activity def: "OBSOLETE. Increase in extent, amount, or degree of glycogen synthase kinase 3 activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001287 name: increased guanylyl cyclase activity def: "Increase in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg] synonym: "increased GC activity" EXACT [] synonym: "increased guanylate cyclase activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001288 name: decreased guanylyl cyclase activity def: "Reduction in extent, amount, or degree of guanylyl cyclase activity." [DDB:pg] synonym: "decreased GC activity" EXACT [] synonym: "decreased guanylate cyclase activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001289 name: abolished catalytic activity def: "Complete absence of catalytic activity." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001290 name: abolished 3',5'-cyclic-AMP phosphodiesterase activity def: "Complete absence of 3',5'-cyclic-AMP phosphodiesterase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001291 name: abolished 3',5'-cyclic-GMP phosphodiesterase activity def: "Complete absence of 3',5'-cyclic-GMP phosphodiesterase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001292 name: obsolete abolished actin-dependent ATPase activity def: "OBSOLETE. Complete absence of actin-dependent ATPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001293 name: abolished adenylate cyclase activity def: "Complete absence of adenylate cyclase activity." [DDB:pg] synonym: "abolished ACA activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001294 name: obsolete abolished glycogen synthase kinase 3 activity def: "OBSOLETE. Complete inability for glycogen synthase kinase 3 activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001295 name: abolished guanylyl cyclase activity def: "Complete absence of guanylyl cyclase activity." [DDB:pg] synonym: "abolished GC activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001296 name: obsolete abolished GTP-gamma-S-stimulated guanylyl cyclase activity def: "OBSOLETE. Complete inability for GTP-gamma-S-stimulated guanylyl cyclase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001297 name: abolished lysosomal protein degradation def: "Complete absence of lysosomal protein degradation." [DDB:pf] synonym: "abolished lysosomal protein catabolic process" EXACT [] synonym: "abolished lysosomal enzyme activity" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001298 name: obsolete abolished protein kinase A activity def: "OBSOLETE. Complete inability for protein kinase A activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001299 name: abolished guanyl-nucleotide exchange factor activity def: "Complete absence of guanyl-nucleotide exchange factor activity." [DDB:pf] synonym: "abolished GEF activity" EXACT [] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001300 name: obsolete abolished protein kinase B activity def: "OBSOLETE. Complete inability for protein kinase B activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001301 name: obsolete decreased protein kinase B activity def: "OBSOLETE. Reduction in extent, amount ordegree of protein kinase B activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001302 name: obsolete increased protein kinase B activity def: "OBSOLETE. Increase in extent, amount, or degree of protein kinase B activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001303 name: obsolete aberrant regulation of catalytic activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the regulation of a catalytic activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001304 name: obsolete aberrant regulation of adenylate cyclase activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the regulation of the activity of adenylate cyclase." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001305 name: abolished cGMP-mediated signaling def: "Complete inability for cGMP signaling." [DDB:pf] synonym: "abolished cAMP induced cGMP pulse" RELATED [] synonym: "abolished cyclic GMP-mediated signaling" EXACT [] is_a: DDPHENO:0000694 ! aberrant cGMP-mediated signaling [Term] id: DDPHENO:0001306 name: obsolete abolished cAMP-induced cAMP pulse def: "OBSOLETE. Complete inability to produce a cAMP pulse upon cAMP stimulation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001307 name: obsolete abolished activation of Rab GTPase activity def: "OBSOLETE. Complete inability for activation of of Rab GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001308 name: obsolete abolished activation of Rac GTPase activity def: "OBSOLETE. Complete inability for activation of of Rac GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001309 name: obsolete abolished activation of Ran GTPase activity def: "OBSOLETE. Complete inability for activation of of Ran GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001310 name: obsolete abolished activation of Rap GTPase activity def: "OBSOLETE. Complete inability for activation of of Rap GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001311 name: obsolete aberrant activation of GTPase activity def: "OBSOLETE Deviation from the normal, usual, or expected events during the activation of the activity of a GTPase." [DDB:pg] comment: GO:0090630. is_obsolete: true [Term] id: DDPHENO:0001312 name: obsolete abolished activation of Ras GTPase activity def: "OBSOLETE. Complete inability for activation of of Ras GTPase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001313 name: obsolete aberrant peptidyl-proline 4-dioxygenase activity def: "OBSOLETE. Deviation from the normal, usual, or expected events during peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001314 name: obsolete decreased peptidyl-proline 4-dioxygenase activity def: "OBSOLETE. Reduction in extent, amount or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001315 name: obsolete increased peptidyl-proline 4-dioxygenase activity def: "OBSOLETE Increase in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001316 name: obsolete abolished peptidyl-proline 4-dioxygenase activity def: "OBSOLETE. Complete inability for peptidyl-proline 4-dioxygenase activity." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001317 name: aberrant protein modification def: "Deviation from the normal, usual, or expected during protein modification." [DDB:pg] synonym: "aberrant protein modification process" EXACT [] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process [Term] id: DDPHENO:0001318 name: obsolete aberrant peptidyl-proline modification def: "OBSOLETE Deviation from the normal, usual, or expected during peptidyl-proline modification." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001319 name: increased peptidyl-proline 4-dioxygenase activity def: "Increase in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pf] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline 4-dioxygenase activity [Term] id: DDPHENO:0001320 name: decreased peptidyl-proline 4-dioxygenase activity def: "Reduction in extent, amount, or degree of peptidyl-proline 4-dioxygenase activity." [DDB:pf] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline 4-dioxygenase activity [Term] id: DDPHENO:0001321 name: aberrant peptidyl-proline 4-dioxygenase activity def: "Deviation from the normal, usual, or expected peptidyl-proline 4-dioxygenase activity." [DDB:pf] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001322 name: abolished peptidyl-proline 4-dioxygenase activity def: "Complete absence of peptidyl-proline 4-dioxygenase activity." [DDB:pf] is_a: DDPHENO:0001321 ! aberrant peptidyl-proline 4-dioxygenase activity [Term] id: DDPHENO:0001323 name: obsolete increased peptidyl-proline hydroxylation def: "OBSOLETE Increase in level of hydroxylation of proline residues on a peptide." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001324 name: obsolete decreased peptidyl-proline hydroxylation def: "OBSOLETE Reduction in level of hydroxylation of proline residues on a peptide." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001325 name: obsolete abolished peptidyl-proline hydroxylation def: "OBSOLETE Complete inability for peptidyl-proline hydroxylation." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001326 name: increased protein modification def: "Increase in level of modification of a protein." [DDB:pg] synonym: "increased protein modification process" EXACT [] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001327 name: decreased protein modification def: "Reduction in level of modification of a protein." [DDB:pg] synonym: "decreased protein modification process" EXACT [] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001328 name: abolished protein modification def: "Complete inability for protein modification." [DDB:pg] synonym: "abolished protein modification process" EXACT [] is_a: DDPHENO:0001317 ! aberrant protein modification [Term] id: DDPHENO:0001329 name: obsolete decreased extracellular cAMP level def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular cAMP level." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001330 name: obsolete increased extracellular cAMP level def: "OBSOLETE. Increase in extent, amount, or degree of cAMP level." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001331 name: aberrant catalase activity def: "Deviation from the normal, usual, or expected activity catalase." [DDB:pg] is_a: DDPHENO:0001105 ! aberrant catalytic activity [Term] id: DDPHENO:0001332 name: abolished catalase activity def: "Complete absence of catalase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001333 name: decreased catalase activity def: "Reduction in extent, amount, or degree of catalase activity." [DDB:pg] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001334 name: increased catalase activity def: "Increase in extent, amount, or degree of catalase activity." [DDB:pg] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001335 name: aberrant protein localization to plasma membrane alt_id: DDPHENO:0000087 def: "Deviation from the normal, usual, or expected events during localization of a protein from the cytoplasm to the plasma membrane." [DDB:pf] synonym: "aberrant localization to plasma membrane" BROAD [] is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery [Term] id: DDPHENO:0001336 name: aberrant protein localization to nucleus alt_id: DDPHENO:0000083 def: "Deviation from the normal, usual, or expected events during localization of a protein to the nucleus." [DDB:pg] synonym: "aberrant localization to nucleus" BROAD [] synonym: "aberrant nuclear protein localization" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001337 name: increased protein localization def: "Increase in amount or accumulation of a protein at a certain location." [DDB:pg] comment: Use for the altered localization of a protein that is affected by the mutation of another gene product. is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001338 name: decreased protein localization def: "Reduction in amount or accumulation of a protein at a certain location." [DDB:pg] comment: Use for the altered localization of a protein that is affected by the mutation of another gene product. is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001339 name: abolished secretion of lysosomal enzymes def: "Complete inability for secretion of lysosomal enzymes." [DDB:pf] is_a: DDPHENO:0001231 ! abolished protein secretion [Term] id: DDPHENO:0001340 name: decreased protein localization to nucleus alt_id: DDPHENO:0000086 def: "Reduction in amount or accumulation of a protein in the nucleus." [DDB:pg] synonym: "decreased localization to nucleus" BROAD [] synonym: "decreased nuclear protein localization" EXACT [] is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001341 name: increased protein localization to nucleus alt_id: DDPHENO:0000085 def: "Increase in amount or accumulation of a protein in the nucleus." [DDB:pg] synonym: "increased localization to nucleus" BROAD [] synonym: "increased nuclear protein localization" EXACT [] is_a: DDPHENO:0001336 ! aberrant protein localization to nucleus is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001342 name: obsolete aberrant protein phosphorylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001343 name: obsolete increased protein phosphorylation def: "OBSOLETE. Increase in amount or accumulation of phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001344 name: obsolete decreased protein phosphorylation def: "OBSOLETE. Reduction in amount or accumulation of phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001345 name: obsolete aberrant protein tyrosine phosphorylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during tyrosine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001346 name: obsolete increased protein tyrosine phosphorylation def: "OBSOLETE. Increase in amount or accumulation of tyrosine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001347 name: obsolete decreased protein threonine phosphorylation def: "OBSOLETE. Reduction in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001348 name: obsolete aberrant protein serine phosphorylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during serine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001349 name: obsolete aberrant protein threonine phosphorylation def: "OBSOLETE. Deviation from the normal, usual, or expected events during threonine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001350 name: obsolete decreased protein serine phosphorylation def: "OBSOLETE. Reduction in amount or accumulation of serine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001351 name: obsolete increased protein serine phosphorylation def: "OBSOLETE. Increase in amount or accumulation of serine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001352 name: obsolete decreased protein tyrosine phosphorylation def: "OBSOLETE. Reduction in amount or accumulation of tyrosine phosphorylation of a protein." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001353 name: obsolete increased protein threonine phosphorylation def: "OBSOLETE. Increase in amount or accumulation of threonine phosphorylation of a protein." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001354 name: aberrant basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the basal disc." [DDB:pg] synonym: "aberrant basal disc development" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis [Term] id: DDPHENO:0001355 name: decreased basal disc size def: "Reduction in relative or proportionate dimensions of the basal disc." [DDB:pg] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001356 name: abolished basal disc formation def: "Complete absence of the basal disc." [DDB:pg] synonym: "abolished basal disc development" EXACT [] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001357 name: aberrant outer basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the outer basal disc." [DDB:pg] synonym: "aberrant outer basal disc development" EXACT [] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001358 name: aberrant inner basal disc formation def: "Deviation from the normal, usual, or expected during the formation of the inner basal disc." [DDB:pg] synonym: "aberrant inner basal disc development" EXACT [] is_a: DDPHENO:0001354 ! aberrant basal disc formation [Term] id: DDPHENO:0001359 name: abolished outer basal disc formation def: "Complete absence of the outer basal disc." [DDB:pg] synonym: "abolished outer basal disc development" EXACT [] is_a: DDPHENO:0001356 ! abolished basal disc formation is_a: DDPHENO:0001357 ! aberrant outer basal disc formation [Term] id: DDPHENO:0001360 name: abolished inner basal disc formation def: "Complete absence of the inner basal disc." [DDB:pg] synonym: "abolished inner basal disc development" EXACT [] is_a: DDPHENO:0001356 ! abolished basal disc formation is_a: DDPHENO:0001358 ! aberrant inner basal disc formation [Term] id: DDPHENO:0001361 name: decreased inner basal disc size def: "Reduction in relative or proportionate dimensions of the inner basal disc." [DDB:pg] is_a: DDPHENO:0001355 ! decreased basal disc size [Term] id: DDPHENO:0001362 name: decreased outer basal disc size def: "Reduction in relative or proportionate dimensions of the outer basal disc." [DDB:pg] is_a: DDPHENO:0001355 ! decreased basal disc size [Term] id: DDPHENO:0001363 name: increased inner basal disc size def: "Increase in relative or proportionate dimensions of the inner basal disc." [DDB:pg] is_a: DDPHENO:0000269 ! increased basal disc size [Term] id: DDPHENO:0001364 name: increased outer basal disc size def: "Increase in relative or proportionate dimensions of the outer basal disc." [DDB:pg] is_a: DDPHENO:0000269 ! increased basal disc size [Term] id: DDPHENO:0001365 name: aberrant lower cup formation def: "Deviation from the normal, usual, or expected morphology of the lower cup." [DDB:pg] synonym: "aberrant lower cup development" EXACT [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0001366 name: aberrant upper cup formation def: "Deviation from the normal, usual, or expected morphology of the upper cup." [DDB:pg] synonym: "aberrant upper cup development" EXACT [] is_a: DDPHENO:0000384 ! aberrant sorus morphology [Term] id: DDPHENO:0001367 name: abolished lower cup formation def: "Complete inability to form a lower cup." [DDB:pg] synonym: "abolished lower cup development" EXACT [] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001368 name: abolished upper cup formation def: "Complete inability to form an upper cup." [DDB:pg] synonym: "abolished upper cup development" EXACT [] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001369 name: increased lower cup size def: "Increase in relative or proportionate dimensions of the lower cup." [DDB:pg] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001370 name: decreased lower cup size def: "Reduction in relative or proportionate dimensions of the lower cup." [DDB:pg] is_a: DDPHENO:0001365 ! aberrant lower cup formation [Term] id: DDPHENO:0001371 name: increased upper cup size def: "Increase in relative or proportionate dimensions of the upper cup." [DDB:pg] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001372 name: decreased upper cup size def: "Reduction in relative or proportionate dimensions of the upper cup." [DDB:pg] is_a: DDPHENO:0001366 ! aberrant upper cup formation [Term] id: DDPHENO:0001373 name: decreased chemotaxis to arachidonic acid def: "Reduction in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf] is_a: DDPHENO:0000099 ! decreased chemotaxis rate [Term] id: DDPHENO:0001374 name: increased chemotaxis to arachidonic acid def: "Increase in extent, amount, or degree of chemotaxis in response to arachidonic acid." [DDB:pf] is_a: DDPHENO:0000400 ! increased chemotaxis rate [Term] id: DDPHENO:0001375 name: aberrant cellular homeostasis def: "Deviation from the normal, usual, or expected events during cellular homeostasis." [DDB:pg] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001376 name: increased glycogen level def: "Increase in amount or accumulation of intracellular glycogen." [DDB:pg] synonym: "increased cytosolic glycogen level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001377 name: increased regulation of intracellular pH def: "Increase in the intracellular pH." [DDB:pf] synonym: "elevation of cellular pH," EXACT [] synonym: "increased cytosolic pH level" EXACT [] synonym: "intracellular pH elevation" EXACT [] is_a: DDPHENO:0001455 ! aberrant regulation of intracellular pH [Term] id: DDPHENO:0001378 name: decreased ammonia level alt_id: DDPHENO:0001379 def: "Reduction in amount or accumulation of ammonia." [DDB:pf] synonym: "decreased cytosolic ammonia level" NARROW [] synonym: "decreased extracellular ammonia level" NARROW [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis [Term] id: DDPHENO:0001381 name: obsolete decreased extracellular glucose level def: "OBSOLETE. Reduction in extent, amount or accumulation of extracellular glucose." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001382 name: obsolete increased extracellular glucose level def: "OBSOLETE. Increase in amount or accumulation of extracellular glucose." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001383 name: obsolete decreased extracellular pteridine level def: "OBSOLETE. Reduction in extent, amount, or accumulation of extracellular pteridine level." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001384 name: decreased cytochrome C oxidase activity def: "Reduction in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg] synonym: "decreased COX activity" EXACT [] is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001385 name: increased cytochrome C oxidase activity def: "Increase in extent, amount, or degree of cytochrome C oxidase activity." [DDB:pg] synonym: "increased COX activity" EXACT [] is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001386 name: abolished cytochrome C oxidase activity def: "Complete absence of cytochrome C oxidase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001387 name: obsolete aberrant CRAC localization to the plasma membrane def: "OBSOLETE. Deviation from the normal, usual, or expected events during CRAC localization to the plasma membrane." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001388 name: obsolete increased CRAC localization to the plasma membrane def: "OBSOLETE. Increase in extent, amount, or degree of CRAC localization to the plasma membrane." [DDB:pg] is_obsolete: true [Term] id: DDPHENO:0001389 name: aberrant protein localization to cytoplasm alt_id: DDPHENO:0000066 def: "Deviation from the normal, usual, or expected events during localization of a protein to the cytoplasm." [DDB:pg] synonym: "aberrant localization to cytoplasm" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001390 name: increased protein localization to cytoplasm alt_id: DDPHENO:0000068 def: "Increase in amount or accumulation of a protein in the cytoplasm." [DDB:pg] synonym: "increased localization to cytoplasm" BROAD [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm [Term] id: DDPHENO:0001391 name: decreased protein localization to cytoplasm alt_id: DDPHENO:0000069 def: "Reduction in amount or accumulation of a protein in the cytoplasm." [DDB:pg] synonym: "decreased localization to cytoplasm" BROAD [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm [Term] id: DDPHENO:0001392 name: abolished protein localization to cytoplasm alt_id: DDPHENO:0000067 def: "Complete inability to localize a protein to the cytoplasm." [DDB:pf, DDB:pg] synonym: "abolished localization to cytoplasm" BROAD [] is_a: DDPHENO:0001389 ! aberrant protein localization to cytoplasm is_a: DDPHENO:0001393 ! abolished protein localization [Term] id: DDPHENO:0001393 name: abolished protein localization def: "Complete inability to localize a protein to a cellular compartment or structure." [DDB:pf, DDB:pg] comment: Use for the abolished localization of a protein that is affected by the mutation of another gene product. is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001394 name: abolished protein localization to plasma membrane alt_id: DDPHENO:0000088 def: "Complete inability to localize a protein to the plasma membrane." [DDB:pf, DDB:pg] synonym: "abolished localization to plasma membrane" BROAD [] is_a: DDPHENO:0000673 ! abolished protein localization to cell periphery is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane [Term] id: DDPHENO:0001395 name: decreased protein localization to plasma membrane alt_id: DDPHENO:0000089 def: "Reduction in the ability for localization of a protein from the cytoplasm to the plasma." [DDB:pf, DDB:pg] synonym: "decreased localization to plasma membrane" BROAD [] is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane is_a: DDPHENO:0001338 ! decreased protein localization [Term] id: DDPHENO:0001396 name: increased protein localization to plasma membrane alt_id: DDPHENO:0000091 def: "Increase in the ability for localization of a protein from the cytoplasm to the plasma membrane." [DDB:pf, DDB:pg] synonym: "increased localization to plasma membrane" BROAD [] is_a: DDPHENO:0001335 ! aberrant protein localization to plasma membrane is_a: DDPHENO:0001337 ! increased protein localization [Term] id: DDPHENO:0001397 name: increased oscillatory cAMP signaling def: "Extended duration for oscillatory cAMP signaling during early development." [DDB:pf] synonym: "increased cAMP relay" EXACT [] synonym: "increased cAMP-induced cAMP pulse" EXACT [] is_a: DDPHENO:0001245 ! aberrant oscillatory cAMP signaling [Term] id: DDPHENO:0001398 name: decreased oscillatory cAMP signaling def: "Shortened duration for oscillatory cAMP signaling during early development." [DDB:pf] synonym: "decreased cAMP-induced cAMP pulse" EXACT [] synonym: "shortened cAMP relay" EXACT [] is_a: DDPHENO:0001245 ! aberrant oscillatory cAMP signaling [Term] id: DDPHENO:0001399 name: abolished protein localization to microtubules alt_id: DDPHENO:0000075 def: "Complete inability to localize a protein to the to microtubules." [DDB:pf] synonym: "abolished localization to microtubules" BROAD [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules [Term] id: DDPHENO:0001400 name: abolished protein localization to microtubule organizing center alt_id: DDPHENO:0000071 def: "Complete inability to localize a protein to the microtubule organizing center." [DDB:pf] synonym: "abolished localization to microtubule organizing center" BROAD [] synonym: "abolished protein localization to the MTOC" EXACT [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center [Term] id: DDPHENO:0001401 name: decreased protein localization to microtubule organizing center alt_id: DDPHENO:0000073 def: "Reduction in amount or accumulation of a protein to the microtubule organizing center." [DDB:pf] synonym: "decreased localization to microtubule organizing center" BROAD [] synonym: "decreased protein localization to the MTOC" EXACT [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center [Term] id: DDPHENO:0001402 name: decreased protein localization to microtubules alt_id: DDPHENO:0000076 def: "Reduction in amount or accumulation of a protein at the microtubules." [DDB:pf] synonym: "decreased localization to microtubules" BROAD [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules [Term] id: DDPHENO:0001403 name: increased protein localization to microtubules alt_id: DDPHENO:0000078 def: "Increase in amount or accumulation of a protein at the microtubules." [DDB:pf] synonym: "increased localization to microtubules" BROAD [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001514 ! aberrant protein localization to microtubules [Term] id: DDPHENO:0001404 name: increased protein localization to microtubule organizing center alt_id: DDPHENO:0000072 def: "Increase in amount or accumulation of a protein to the microtubule organizing center." [DDB:pf] synonym: "increased localization to microtubule organizing center" BROAD [] synonym: "increased protein localization to the MTOC" EXACT [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001513 ! aberrant protein localization to microtubule organizing center [Term] id: DDPHENO:0001405 name: abolished protein localization to clathrin-coated pit alt_id: DDPHENO:0000063 def: "Complete inability to localize a protein to coated pits." [DDB:pf] synonym: "abolished localization to coated pits" BROAD [] synonym: "abolished protein localization to coated pits" EXACT [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001408 ! aberrant protein localization to clathrin-coated pit [Term] id: DDPHENO:0001406 name: decreased protein localization to clathrin-coated pit alt_id: DDPHENO:0000065 def: "Reduction in amount or accumulation of a protein to coated pits." [DDB:pf] synonym: "decreased localization to coated pits" BROAD [] synonym: "decreased protein localization to coated pits" EXACT [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001408 ! aberrant protein localization to clathrin-coated pit [Term] id: DDPHENO:0001407 name: increased protein localization to clathrin-coated pit alt_id: DDPHENO:0000064 def: "Increase in amount or accumulation of a protein to coated pits." [DDB:pf] synonym: "increased localization to coated pits" BROAD [] synonym: "increased protein localization to coated pits" EXACT [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001408 ! aberrant protein localization to clathrin-coated pit [Term] id: DDPHENO:0001408 name: aberrant protein localization to clathrin-coated pit alt_id: DDPHENO:0000062 def: "Deviation from the normal, usual, or expected events during localization of a protein to coated pits." [DDB:pf] synonym: "aberrant localization to coated pits" BROAD [] synonym: "aberrant protein localization to coated pits" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001409 name: abolished phosphatidylinositol binding def: "Complete absence of phosphatidylinositol binding." [DDB:pf] is_a: DDPHENO:0000326 ! abolished lipid binding [Term] id: DDPHENO:0001410 name: abolished phosphatidylinositol-4,5-bisphosphate binding def: "Complete absence of phosphatidylinositol-4,5-bisphosphate binding." [DDB:pf] is_a: DDPHENO:0001409 ! abolished phosphatidylinositol binding [Term] id: DDPHENO:0001411 name: obsolete aberrant response to conditioned medium factor def: "OBSOLETE. Deviation from the normal, usual, or expected events during the response to conditioned medium factor (CMF) found in conditioned media (CM)." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001412 name: aberrant protein localization to pseudopodium alt_id: DDPHENO:0000092 def: "Deviation from the normal, usual, or expected events during localization of a protein to pseudopodia." [DDB:pf] synonym: "aberrant localization to pseudopodium" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001413 name: decreased protein localization to pseudopodium alt_id: DDPHENO:0000095 def: "Reduction in amount or accumulation of a protein in pseudopodia." [DDB:pf] synonym: "decreased localization to pseudopodium" BROAD [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium [Term] id: DDPHENO:0001414 name: increased protein localization to pseudopodium alt_id: DDPHENO:0000096 def: "Increase in amount or accumulation of a protein in pseudopodia." [DDB:pf] synonym: "increased localization to pseudopodium" BROAD [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium [Term] id: DDPHENO:0001415 name: increased fruiting body size def: "Increase in relative or proportionate dimensions of the fruiting body." [DDB:pf] synonym: "increased sorocarp size" EXACT [] synonym: "large fruiting body" EXACT [] is_a: DDPHENO:0000009 ! aberrant fruiting body morphogenesis [Term] id: DDPHENO:0001416 name: aberrant cell separation during cytokinesis def: "Deviation from the normal, usual, or expected events during cell separation during cytokinesis." [DDB:pf] synonym: "aberrant midbody abscission" EXACT [] is_a: DDPHENO:0000149 ! aberrant cytokinesis [Term] id: DDPHENO:0001417 name: delayed cell separation during cytokinesis def: "Late onset or slower progression for cell separation during cytokinesis." [DDB:pf] synonym: "delayed midbody abscission" EXACT [] is_a: DDPHENO:0001169 ! delayed cytokinesis is_a: DDPHENO:0001416 ! aberrant cell separation during cytokinesis [Term] id: DDPHENO:0001418 name: aberrant cell cycle def: "Deviation from the normal, usual, or expected cell cycle event." [DDB:pf] is_a: DDPHENO:0001008 ! aberrant cellular process [Term] id: DDPHENO:0001419 name: aberrant mitotic spindle organization def: "Deviation from the normal, usual, or expected during mitotic spindle organization." [DDB:pf] synonym: "mitotic spindle stabilisation" RELATED [] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0001420 name: precocious mitotic spindle elongation def: "Early onset or faster progression through mitotic spindle elongation." [DDB:pf] is_a: DDPHENO:0001486 ! aberrant mitotic spindle elongation [Term] id: DDPHENO:0001421 name: obsolete decreased spindle stabilisation def: "OBSOLETE. Reduction in spindle stabilisation." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001422 name: aberrant mitotic sister chromatid segregation def: "Deviation from the normal, usual, or expected events during mitotic sister chromosome segregation, resulting in an abnormal number of chromosomes." [DDB:pf] synonym: "aberrant sister chromatid segregation" EXACT [] synonym: "aneuploidy" RELATED [] is_a: DDPHENO:0000234 ! aberrant mitosis [Term] id: DDPHENO:0001423 name: aberrant nuclear envelope morphology def: "Deviation from the normal, usual, or expected morphology of the nuclear envelope." [DDB:pf] is_a: DDPHENO:0000263 ! aberrant nucleus morphology [Term] id: DDPHENO:0001424 name: aberrant nuclear membrane organization def: "Deviation from the normal, usual, or expected morphology of the perinuclear space during nuclear membrane organization." [DDB:pf] synonym: "aberrant nuclear membrane lumen" RELATED [] is_a: DDPHENO:0001423 ! aberrant nuclear envelope morphology [Term] id: DDPHENO:0001425 name: aberrant centrosome organization def: "Deviation from the normal, usual, or expected events during centrosome organization." [DDB:pf] synonym: "aberrant centrosome cycle" EXACT [] is_a: DDPHENO:0001043 ! aberrant organelle organization [Term] id: DDPHENO:0001426 name: increased number of centrosomes def: "Quantitative increase in centrosomes." [DDB:pf] is_a: DDPHENO:0001425 ! aberrant centrosome organization [Term] id: DDPHENO:0001427 name: aberrant protein localization to nuclear envelope alt_id: DDPHENO:0000079 def: "Deviation from the normal, usual, or expected events during localization of a protein to the nuclear envelope." [DDB:pf] synonym: "aberrant localization to nuclear envelope" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization [Term] id: DDPHENO:0001428 name: abolished protein localization to nuclear envelope alt_id: DDPHENO:0000080 def: "Complete inability to localize a protein to the nuclear envelope." [DDB:pf] synonym: "abolished localization to nuclear envelope" BROAD [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope [Term] id: DDPHENO:0001429 name: decreased protein localization to nuclear envelope alt_id: DDPHENO:0000082 def: "Reduction in amount or accumulation of a protein at the nuclear envelope." [DDB:pf] synonym: "decreased localization to nuclear envelope" BROAD [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope [Term] id: DDPHENO:0001430 name: increased protein localization to nuclear envelope alt_id: DDPHENO:0000081 def: "Increase in amount or accumulation of a protein in the nuclear envelope." [DDB:pf] synonym: "increased localization to nuclear envelope" BROAD [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001427 ! aberrant protein localization to nuclear envelope [Term] id: DDPHENO:0001431 name: aberrant development of tipped mound def: "Deviation from the normal, usual, or expected events during development of tipped mound." [DDB:pf] synonym: "aberrant sorocarp development of tipped mound" EXACT [] synonym: "aberrant tip formation" RELATED [] is_a: DDPHENO:0000154 ! aberrant sorocarp development [Term] id: DDPHENO:0001432 name: delayed sporulation def: "Late onset or slower progression through spore formation." [DDB:pf] synonym: "delayed asexual sporulation" EXACT [] is_a: DDPHENO:0000513 ! aberrant sporulation [Term] id: DDPHENO:0001433 name: aberrant GABA signaling pathway def: "Deviation from the normal, usual, or expected events during the gamma-aminobutyric acid signaling pathway." [DDB:pf] synonym: "aberrant gamma-aminobutyric acid signaling pathway" EXACT [] is_a: DDPHENO:0001118 ! aberrant signal transduction [Term] id: DDPHENO:0001434 name: abolished histone deacetylase activity def: "Complete absence of histone deacetylase activity." [DDB:pg] is_a: DDPHENO:0001289 ! abolished catalytic activity [Term] id: DDPHENO:0001435 name: decreased histone deacetylase activity def: "Reduction in extent, amount, or degree of histone deacetylase activity." [DDB:pg] comment: GO:0004407. is_a: DDPHENO:0001257 ! decreased catalytic activity [Term] id: DDPHENO:0001436 name: increased histone deacetylase activity def: "Increase in extent, amount, or degree of histone deacetylase activity." [DDB:pg] comment: GO:0004407. is_a: DDPHENO:0001256 ! increased catalytic activity [Term] id: DDPHENO:0001437 name: aberrant programmed necrotic cell death def: "Deviation from the normal, usual, or expected events during programmed necrotic cell death." [DDB:pf] is_a: DDPHENO:0000770 ! aberrant programmed cell death [Term] id: DDPHENO:0001438 name: abolished programmed necrotic cell death def: "Complete inability for programmed necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant programmed necrotic cell death [Term] id: DDPHENO:0001439 name: decreased programmed necrotic cell death def: "Reduction in extent, amount, or degree of programmed necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant programmed necrotic cell death [Term] id: DDPHENO:0001440 name: increased programmed necrotic cell death def: "Increase in extent, amount, or degree of programmed necrotic cell death." [DDB:pf] is_a: DDPHENO:0001437 ! aberrant programmed necrotic cell death [Term] id: DDPHENO:0001441 name: obsolete aberrant cell fate commitment def: "OBSOLETE. Deviation from the normal, usual, or expected events when committing cells for a specific fate in their normal environment." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001442 name: obsolete decreased cell fate commitment def: "OBSOLETE. Reduction in extent, amount, or degree when committing cells for a specific fate in their normal environment." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001443 name: aberrant cell fate determination def: "Deviation from the normal, usual, or expected events when determining cells for a specific fate regardless of its environment." [DDB:pf] is_a: DDPHENO:0001013 ! aberrant cell differentiation [Term] id: DDPHENO:0001444 name: decreased cell fate determination def: "Reduction in extent, amount, or degree when determining cells for a specific fate regardless of its environment." [DDB:pf] is_a: DDPHENO:0001443 ! aberrant cell fate determination [Term] id: DDPHENO:0001445 name: aberrant actin filament polymerization def: "Deviation from the normal, usual, or expected events during F-actin polymerization." [DDB:pf] synonym: "aberrant F-actin polymerization" EXACT [] is_a: DDPHENO:0000151 ! aberrant actin filament organization created_by: pfey creation_date: 2010-02-03T05:27:42Z [Term] id: DDPHENO:0001446 name: aberrant actin filament depolymerization def: "Deviation from the normal, usual, or expected events during F-actin depolymerization." [DDB:pf] synonym: "aberrant F-actin depolymerization" EXACT [] is_a: DDPHENO:0000151 ! aberrant actin filament organization created_by: pfey creation_date: 2010-02-03T05:54:09Z [Term] id: DDPHENO:0001447 name: abolished actin filament depolymerization def: "Complete inability to depolymerize actin into F-actin." [DDB:pf] synonym: "abolished F-actin depolymerization" EXACT [] is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization created_by: pfey creation_date: 2010-02-03T05:57:47Z [Term] id: DDPHENO:0001448 name: decreased actin filament depolymerization def: "Reduction in extent, amount, or degree of F-actin depolymerization." [DDB:pf] synonym: "decreased F-actin depolymerization" EXACT [] is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization created_by: pfey creation_date: 2010-02-03T05:59:24Z [Term] id: DDPHENO:0001449 name: increased actin filament depolymerization def: "Increase in extent, amount, or degree of F-actin depolymerization." [DDB:pf] synonym: "increased F-actin depolymerization" EXACT [] is_a: DDPHENO:0001446 ! aberrant actin filament depolymerization created_by: pfey creation_date: 2010-02-03T06:00:17Z [Term] id: DDPHENO:0001450 name: obsolete abolished protein phosphorylation def: "OBSOLETE. Complete inability for protein phosphorylation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2010-02-16T04:04:04Z [Term] id: DDPHENO:0001451 name: obsolete abolished actin phosphorylation def: "OBSOLETE. Complete inability for actin phosphorylation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2010-02-16T04:06:48Z [Term] id: DDPHENO:0001452 name: obsolete abolished protein serine phosphorylation def: "OBSOLETE. Complete inability for protein serine phosphorylation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2010-02-16T04:07:35Z [Term] id: DDPHENO:0001453 name: obsolete abolished protein threonine phosphorylation def: "OBSOLETE. Complete inability for protein threonine phosphorylation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2010-02-16T04:08:34Z [Term] id: DDPHENO:0001454 name: obsolete abolished protein tyrosine phosphorylation def: "OBSOLETE. Complete inability for protein tyrosine phosphorylation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2010-02-16T04:08:50Z [Term] id: DDPHENO:0001455 name: aberrant regulation of intracellular pH def: "Deviation from the normal, usual, or expected regulation of the intracellular pH." [DDB:pf] comment: GO:0051453. synonym: "aberrant intracellular pH level" EXACT [] is_a: DDPHENO:0001375 ! aberrant cellular homeostasis created_by: pfey creation_date: 2010-02-19T11:12:47Z [Term] id: DDPHENO:0001456 name: aberrant response to cisplatin def: "Deviation from the normal, usual, or expected events during the response to cisplatin." [DDb:pg] comment: GO:0072718. is_a: DDPHENO:0001031 ! aberrant response to abiotic stimulus created_by: Pascale creation_date: 2010-03-10T09:58:37Z [Term] id: DDPHENO:0001457 name: obsolete aberrant DNA repair def: "OBSOLETE. Deviation from the normal, usual, or expected events during DNA repair." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-10T10:44:05Z [Term] id: DDPHENO:0001458 name: obsolete aberrant double-strand break repair via homologous recombination def: "OBSOLETE. Deviation from the normal, usual, or expected events during double-strand break repair via homologous recombination." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-10T10:44:20Z [Term] id: DDPHENO:0001459 name: obsolete decreased double-strand break repair via homologous recombination def: "OBSOLETE. Reduction in extent, amount, or degree of double-strand break repair via homologous recombination." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-10T10:44:37Z [Term] id: DDPHENO:0001460 name: obsolete increased double-strand break repair via homologous recombination def: "OBSOLETE. Increase in amount or rate of double-strand break repair via homologous recombination." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-10T10:44:51Z [Term] id: DDPHENO:0001461 name: obsolete aberrant chemotaxis to cAMP in response to DIF-1 def: "OBSOLETE. Deviation from the normal, usual, or expected events during chemotaxis to cAMP in response to DIF-1." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-15T04:04:23Z [Term] id: DDPHENO:0001462 name: obsolete aberrant chemotaxis to cAMP in response to DIF-2 def: "OBSOLETE. Deviation from the normal, usual, or expected events during chemotaxis to cAMP in response to DIF-2." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-15T04:05:48Z [Term] id: DDPHENO:0001463 name: aberrant regulation of positive chemotaxis def: "Deviation from the normal, usual, or expected events during the regulation of the locomotory response." [DDB:pf] is_a: DDPHENO:0001224 ! aberrant positive chemotaxis created_by: Pascale creation_date: 2010-03-15T04:20:58Z [Term] id: DDPHENO:0001464 name: obsolete aberrant regulation of chemotaxis to cAMP in response to DIF-1 def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of chemotaxis to cAMP in response to DIF-1." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-15T04:24:28Z [Term] id: DDPHENO:0001465 name: obsolete aberrant regulation of chemotaxis to cAMP in response to DIF-2 def: "OBSOLETE. Deviation from the normal, usual, or expected events during regulation of chemotaxis to cAMP in response to DIF-2." [DDB:pg] is_obsolete: true created_by: Pascale creation_date: 2010-03-15T04:25:54Z [Term] id: DDPHENO:0001466 name: aberrant microtubule nucleation def: "Deviation from the normal, usual, or expected events during microtubule nucleation." [DDB:pf] xref: DDB:pf is_a: DDPHENO:0000413 ! aberrant microtubule cytoskeleton organization created_by: pfey creation_date: 2010-03-17T02:07:26Z [Term] id: DDPHENO:0001467 name: decreased microtubule nucleation def: "Reduction in extent, amount, or degree of microtubule nucleation." [DDB:pf] is_a: DDPHENO:0001466 ! aberrant microtubule nucleation created_by: pfey creation_date: 2010-03-17T02:16:06Z [Term] id: DDPHENO:0001468 name: increased microtubule nucleation def: "Increase in amount or rate of microtubule nucleation." [DDB:pf] is_a: DDPHENO:0001466 ! aberrant microtubule nucleation created_by: pfey creation_date: 2010-03-17T02:20:17Z [Term] id: DDPHENO:0001469 name: aberrant centromere complex assembly def: "Deviation from the normal, usual, or expected events during centromere complex assembly." [DDB:pf] is_a: DDPHENO:0001043 ! aberrant organelle organization created_by: pfey creation_date: 2010-03-19T03:00:52Z [Term] id: DDPHENO:0001470 name: decreased response to lithium def: "Reduction in extent, amount, or degree of response to lithium." [DDB:pf] synonym: "decreased response to lithium ion" EXACT [] is_a: DDPHENO:0001108 ! aberrant response to lithium created_by: pfey creation_date: 2010-09-06T12:50:53Z [Term] id: DDPHENO:0001471 name: increased response to lithium def: "Increase in extent, amount, or degree of response to lithium." [DDB:pf] synonym: "increased response to lithium ion" EXACT [] is_a: DDPHENO:0001108 ! aberrant response to lithium created_by: pfey creation_date: 2010-09-06T12:54:23Z [Term] id: DDPHENO:0001472 name: aberrant inositol phosphate metabolic process def: "Deviation from the normal, usual, or expected events during inositol phosphate metabolism." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2011-03-24T02:17:45Z [Term] id: DDPHENO:0001473 name: aberrant glucose catabolic process def: "Deviation from the normal, usual, or expected events during glucose catabolism." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2011-03-24T02:22:00Z [Term] id: DDPHENO:0001474 name: obsolete increased intracellular 2,3-bisphosphoglycerate def: "OBSOLETE. Increase in amount or accumulation of intracellular 2,3-bisphosphoglycerate." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2011-03-24T02:29:08Z [Term] id: DDPHENO:0001475 name: obsolete abolished histone H3-K79 methylation def: "OBSOLETE Complete inability for methylation of histone H3 at lysine 79." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2011-09-13T10:47:22Z [Term] id: DDPHENO:0001476 name: obsolete abolished histone lysine methylation def: "OBSOLETE Complete inability for methylation of a lysine in histone H3." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2011-09-13T10:54:35Z [Term] id: DDPHENO:0001477 name: obsolete abolished histone H3-K9 methylation def: "OBSOLETE Complete inability for methylation of histone H3 at lysine 9." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2011-09-13T10:57:06Z [Term] id: DDPHENO:0001478 name: abolished cell-cell adhesion def: "Complete inability of cell-cell adhesion." [DDB:pf] is_a: DDPHENO:0000412 ! aberrant cell-cell adhesion created_by: pfey creation_date: 2011-09-13T11:17:59Z [Term] id: DDPHENO:0001479 name: abolished calcium-dependent cell-cell adhesion def: "Complete inability of calcium-dependent cell-cell adhesion." [DDB:pf] synonym: "abolished calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "abolished EDTA-sensitive cell-cell adhesion" RELATED [] is_a: DDPHENO:0001478 ! abolished cell-cell adhesion created_by: pfey creation_date: 2011-09-13T11:19:21Z [Term] id: DDPHENO:0001480 name: abolished calcium-independent cell-cell adhesion def: "Complete inability of calcium-independent cell-cell adhesion." [DDB:pf] synonym: "abolished calcium-independent cell-cell adhesion via plasma membrane cell adhesion molecules" EXACT [] synonym: "abolished EDTA-resistant cell adhesion" RELATED [] is_a: DDPHENO:0001478 ! abolished cell-cell adhesion created_by: pfey creation_date: 2011-09-13T11:21:46Z [Term] id: DDPHENO:0001481 name: aberrant actin cytoskeleton organization def: "Deviation from the normal, usual, or expected events during organization of the actin cytoskeleton." [DDB:pf] is_a: DDPHENO:0000397 ! aberrant cytoskeleton organization [Term] id: DDPHENO:0001482 name: aberrant cortical actin cytoskeleton organization def: "Deviation from the normal, usual, or expected events during organization of the cortical actin cytoskeleton." [DDB:pf] synonym: "aberrant cortical actin cytoskeleton stabilisation" RELATED [] is_a: DDPHENO:0001481 ! aberrant actin cytoskeleton organization [Term] id: DDPHENO:0001483 name: obsolete aberrant cortical actin cytoskeleton stabilisation def: "OBSOLETE. Deviation from the normal, usual, or expected events in the maintenance of the cortical actin cytoskeleton." [DDB:pf] is_obsolete: true [Term] id: DDPHENO:0001484 name: obsolete aberrant spindle stabilisation def: "OBSOLETE. Deviation from the normal, usual, or expected during spindle stabilisation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2012-04-16T01:41:00Z [Term] id: DDPHENO:0001485 name: obsolete increased spindle stabilisation def: "OBSOLETE. Increase in spindle stabilisation." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2012-04-16T01:51:35Z [Term] id: DDPHENO:0001486 name: aberrant mitotic spindle elongation def: "Deviation from the normal, usual, or expected during mitotic spindle elongation." [DDB:pf] is_a: DDPHENO:0001419 ! aberrant mitotic spindle organization created_by: pfey creation_date: 2012-04-16T01:52:48Z [Term] id: DDPHENO:0001487 name: delayed mitotic spindle elongation def: "Late onset or slower progression of the mitotic spindle elongation." [DDB:pf] is_a: DDPHENO:0001486 ! aberrant mitotic spindle elongation created_by: pfey creation_date: 2012-04-16T01:54:39Z [Term] id: DDPHENO:0001488 name: aberrant phagosome maturation def: "Deviation from the normal, usual, or expected events during phagosome maturation." [DDB:pf] is_a: DDPHENO:0001006 ! aberrant phagocytosis created_by: pfey creation_date: 2012-05-22T05:06:53Z [Term] id: DDPHENO:0001489 name: abolished phagosome acidification def: "Complete inability for phagosome acidification." [DDB:pf] is_a: DDPHENO:0001488 ! aberrant phagosome maturation created_by: pfey creation_date: 2012-05-22T05:10:55Z [Term] id: DDPHENO:0001490 name: precocious phagosome acidification def: "Early onset or faster progression of phagosome acidification." [DDB:pf] is_a: DDPHENO:0001488 ! aberrant phagosome maturation created_by: pfey creation_date: 2012-05-22T05:15:21Z [Term] id: DDPHENO:0001491 name: delayed phagosome acidification def: "Late onset or slower progression of phagosome acidification." [DDB:pf] is_a: DDPHENO:0001488 ! aberrant phagosome maturation created_by: pfey creation_date: 2012-05-22T05:19:42Z [Term] id: DDPHENO:0001492 name: delayed phagosome reneutralization def: "Late onset or slower progression of phagosome reneutralization." [DDB:pf] is_a: DDPHENO:0001488 ! aberrant phagosome maturation created_by: pfey creation_date: 2012-05-22T05:22:18Z [Term] id: DDPHENO:0001493 name: obsolete aberrant mitochondrion distribution def: "OBSOLETE. Deviation from the normal, usual, or expected events during mitochondrion distribution." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2012-05-30T05:44:25Z [Term] id: DDPHENO:0001494 name: aberrant intracellular distribution of mitochondria def: "Deviation from the normal, usual, or expected events during intracellular distribution of mitochondria." [DDB:pf] synonym: "aberrant mitochondria positioning within cell" EXACT [] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization created_by: pfey creation_date: 2012-05-30T05:45:34Z [Term] id: DDPHENO:0001495 name: decreased phagolysosome size def: "Reduction in relative or proportional dimensions of the phagolysosome." [DDB:pf] is_a: DDPHENO:0001222 ! aberrant phagolysosome formation created_by: pfey creation_date: 2012-05-30T05:58:22Z [Term] id: DDPHENO:0001496 name: increased phagolysosome size def: "Increase in relative or proportional dimensions of the phagolysosome." [DDB:pf] is_a: DDPHENO:0001222 ! aberrant phagolysosome formation created_by: pfey creation_date: 2012-05-30T05:59:28Z [Term] id: DDPHENO:0001497 name: abolished protein localization to cell surface alt_id: DDPHENO:0000059 def: "Complete inability to localize a protein to the cell surface." [DDB:pf] synonym: "abolished localization to cell surface" BROAD [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface created_by: pfey creation_date: 2012-09-26T05:18:28Z [Term] id: DDPHENO:0001498 name: decreased protein localization to cell surface alt_id: DDPHENO:0000061 def: "Reduction in amount or accumulation of a protein on the cell surface." [DDB:pf] synonym: "decreased localization to cell surface" BROAD [] xref: DDB:pf is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface created_by: pfey creation_date: 2012-09-26T05:24:53Z [Term] id: DDPHENO:0001499 name: increased protein localization to cell surface alt_id: DDPHENO:0000060 def: "Increase in amount or accumulation of a protein to the cell surface." [DDB:pf] synonym: "increased localization to cell surface" BROAD [] xref: DDB:pf is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001511 ! aberrant protein localization to cell surface created_by: pfey creation_date: 2012-09-26T05:36:48Z [Term] id: DDPHENO:0001500 name: aberrant protein stabilization def: "Deviation from the normal, usual, or expected stabilization of proteins." [DDB:pf] is_a: DDPHENO:0001241 ! aberrant protein level created_by: pfey creation_date: 2012-09-26T05:42:31Z [Term] id: DDPHENO:0001501 name: decreased protein stabilization def: "Reduction in extent, amount, or degree of protein stabilization." [DDB:pf] is_a: DDPHENO:0001500 ! aberrant protein stabilization created_by: pfey creation_date: 2012-09-26T05:44:26Z [Term] id: DDPHENO:0001502 name: increased protein stabilization def: "Increase in extent, amount, or degree of protein stabilization." [DDB:pf] is_a: DDPHENO:0001500 ! aberrant protein stabilization created_by: pfey creation_date: 2012-09-26T05:44:42Z [Term] id: DDPHENO:0001503 name: abolished protein stabilization def: "Complete elimination of protein stabilization." [DDB:pf] is_a: DDPHENO:0001500 ! aberrant protein stabilization created_by: pfey creation_date: 2012-09-26T05:44:58Z [Term] id: DDPHENO:0001504 name: aberrant cellular response to cation stress def: "Deviation from the normal, usual, or expected events during the cellular response to cation stress." [DDB:pf] is_a: DDPHENO:0001034 ! aberrant cellular response to stress created_by: pfey creation_date: 2012-10-04T14:20:48Z [Term] id: DDPHENO:0001505 name: aberrant cellular defence response def: "Deviation from the normal, usual, or expected response triggered in response to the presence of a foreign body or the prevention/recovery from an infection." [DDB:pf] is_a: DDPHENO:0001226 ! aberrant cellular response to extracellular stimulus created_by: pfey creation_date: 2012-11-01T15:29:41Z [Term] id: DDPHENO:0001506 name: obsolete aberrant defence response to a microorganism def: "OBSOLETE. Deviation from the normal, usual, or expected response to the presence of a microorganism that acts to protect the cell." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2012-11-01T15:39:11Z [Term] id: DDPHENO:0001507 name: aberrant protein localization to cell cortex alt_id: DDPHENO:0000054 def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell cortex." [DDB:pf] synonym: "aberrant localization to cell cortex" BROAD [] is_a: DDPHENO:0000672 ! aberrant protein localization to cell periphery created_by: pfey creation_date: 2012-11-21T14:21:05Z [Term] id: DDPHENO:0001508 name: abolished protein localization to cell cortex alt_id: DDPHENO:0000055 def: "Complete inability to localize a protein to the cell cortex." [DDB:pf] synonym: "abolished localization to cell cortex" BROAD [] is_a: DDPHENO:0000673 ! abolished protein localization to cell periphery is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex created_by: pfey creation_date: 2012-11-21T14:57:02Z [Term] id: DDPHENO:0001509 name: decreased protein localization to cell cortex alt_id: DDPHENO:0000057 def: "Reduction in amount or accumulation of a protein to the cell cortex." [DDB:pf] synonym: "decreased localization to cell cortex" BROAD [] is_a: DDPHENO:0001338 ! decreased protein localization is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex created_by: pfey creation_date: 2012-11-21T14:59:13Z [Term] id: DDPHENO:0001510 name: increased protein localization to cell cortex alt_id: DDPHENO:0000056 def: "Increase in amount or accumulation of a protein to the cell cortex." [DDB:pf] synonym: "increased localization to cell cortex" BROAD [] is_a: DDPHENO:0001337 ! increased protein localization is_a: DDPHENO:0001507 ! aberrant protein localization to cell cortex created_by: pfey creation_date: 2012-11-21T15:00:30Z [Term] id: DDPHENO:0001511 name: aberrant protein localization to cell surface alt_id: DDPHENO:0000058 def: "Deviation from the normal, usual, or expected events during localization of a protein to the cell surface." [DDB:pf] synonym: "aberrant localization to cell surface" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2012-11-21T16:19:40Z [Term] id: DDPHENO:0001512 name: abolished protein localization to pseudopodium alt_id: DDPHENO:0000093 def: "Complete inability to localize a protein pseudopodia." [DDB:pf] synonym: "abolished localization to pseudopodium" BROAD [] is_a: DDPHENO:0001393 ! abolished protein localization is_a: DDPHENO:0001412 ! aberrant protein localization to pseudopodium created_by: pfey creation_date: 2012-11-21T16:33:42Z [Term] id: DDPHENO:0001513 name: aberrant protein localization to microtubule organizing center alt_id: DDPHENO:0000070 def: "Deviation from the normal, usual, or expected events during localization of a protein to the microtubule organizing center." [DDB:pf] synonym: "aberrant localization to microtubule organizing center" BROAD [] synonym: "aberrant protein localization to the MTOC" EXACT [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2012-11-21T16:41:09Z [Term] id: DDPHENO:0001514 name: aberrant protein localization to microtubules alt_id: DDPHENO:0000074 def: "Deviation from the normal, usual, or expected events during localization of a protein to the microtubules." [DDB:pf] synonym: "aberrant localization to microtubules" BROAD [] is_a: DDPHENO:0000471 ! aberrant protein localization created_by: pfey creation_date: 2012-11-21T16:42:51Z [Term] id: DDPHENO:0001515 name: aberrant mitochondrial fusion def: "Deviation from the normal, usual, or expected events during mitochondrial fusion." [DDB:pf] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization created_by: pfey creation_date: 2012-12-04T16:26:23Z [Term] id: DDPHENO:0001516 name: decreased mitochondrial fusion def: "Quantitative reduction of mitochondrial fusion." [DDB:pf] is_a: DDPHENO:0001515 ! aberrant mitochondrial fusion created_by: pfey creation_date: 2012-12-04T16:28:41Z [Term] id: DDPHENO:0001517 name: increased mitochondrial fusion def: "Quantitative increase in mitochondrial fusion." [DDB:pf] is_a: DDPHENO:0001515 ! aberrant mitochondrial fusion created_by: pfey creation_date: 2012-12-04T16:29:02Z [Term] id: DDPHENO:0001518 name: aberrant mitochondrial fission def: "Deviation from the normal, usual, or expected events during mitochondrial fission." [DDB:pf] is_a: DDPHENO:0001234 ! aberrant mitochondrion organization created_by: pfey creation_date: 2012-12-04T16:29:22Z [Term] id: DDPHENO:0001519 name: decreased mitochondrial fission def: "Quantitative reduction of mitochondrial fission." [DDB:pf] is_a: DDPHENO:0001518 ! aberrant mitochondrial fission created_by: pfey creation_date: 2012-12-04T16:30:43Z [Term] id: DDPHENO:0001520 name: increased mitochondrial fission def: "Quantitative increase in mitochondrial fission." [DDB:pf] is_a: DDPHENO:0001518 ! aberrant mitochondrial fission created_by: pfey creation_date: 2012-12-04T16:31:04Z [Term] id: DDPHENO:0001521 name: aberrant cellular response to fluid shear stress def: "Deviation from the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf] synonym: "aberrant cellular response to mechanical stress" RELATED [] is_a: DDPHENO:0001034 ! aberrant cellular response to stress created_by: pfey creation_date: 2013-01-21T11:10:47Z [Term] id: DDPHENO:0001522 name: obsolete decreased resistance to fluid shear stress def: "OBSOLETE. Decreased tolerance of the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2013-01-21T11:22:51Z [Term] id: DDPHENO:0001523 name: obsolete increased resistance to fluid shear stress def: "OBSOLETE. Increased tolerance of the normal, usual, or expected events during the cellular response to fluid shear stress." [DDB:pf] is_obsolete: true created_by: pfey creation_date: 2013-01-21T11:23:21Z [Term] id: DDPHENO:0001524 name: aberrant chromatin assembly def: "Deviation from the normal, usual, or expected during chromatin assembly." [DDB:pf] is_a: DDPHENO:0001005 ! aberrant cellular metabolic process created_by: pfey creation_date: 2013-01-21T13:29:16Z [Term] id: DDPHENO:0001525 name: increased prestalk U cell differentiation def: "Increase in extent, amount, or degree of differentiation into prestalk U cells." [DDB:pf] synonym: "increased number of prestalk U cells" RELATED [] synonym: "increased pstU cell differentiation" EXACT [] is_a: DDPHENO:0000169 ! increased prestalk cell differentiation is_a: DDPHENO:0001527 ! aberrant prestalk U cell differentiation created_by: pfey creation_date: 2013-02-11T16:28:11Z [Term] id: DDPHENO:0001526 name: decreased prestalk U cell differentiation def: "Reduction in extent, amount, or degree of differentiation into prestalk U cells." [DDB:pf] synonym: "decreased number of prestalk U cells" RELATED [] synonym: "decreased pstU cell differentiation" EXACT [] is_a: DDPHENO:0000191 ! decreased prestalk cell differentiation is_a: DDPHENO:0001527 ! aberrant prestalk U cell differentiation created_by: pfey creation_date: 2013-02-11T16:32:31Z [Term] id: DDPHENO:0001527 name: aberrant prestalk U cell differentiation def: "Deviation from the normal, usual, or expected events during differentiation of prestalk U cells." [DDB:pf] synonym: "aberrant pstU cell differentiation" EXACT [] is_a: DDPHENO:0001023 ! aberrant prestalk cell differentiation created_by: pfey creation_date: 2013-02-11T16:46:03Z [Term] id: DDPHENO:0001528 name: abolished prestalk U cell differentiation def: "Complete inability for differentiation of prestalk U cells." [DDB:pf] synonym: "abolished pstU cell differentiation" EXACT [] is_a: DDPHENO:0000512 ! abolished prestalk cell differentiation is_a: DDPHENO:0001527 ! aberrant prestalk U cell differentiation created_by: pfey creation_date: 2013-02-11T16:56:55Z [Term] id: DDPHENO:0001529 name: aberrant regulation of vegetative growth def: "Deviation from the normal, usual, or expected events during the regulation of vegetative growth." [DDB:pf] synonym: "aberrant regulation of asexual reproduction" EXACT [] synonym: "aberrant regulation of cell proliferation" RELATED [] is_a: DDPHENO:0001084 ! aberrant vegetative growth created_by: pfey creation_date: 2013-02-15T10:39:43Z [Term] id: DDPHENO:0001530 name: aberrant negative regulation of vegetative growth def: "Deviation from the normal, usual, or expected events during the negative regulation of vegetative growth." [DDB:pf] synonym: "aberrant negative regulation of asexual reproduction" EXACT [] synonym: "aberrant negative regulation of cell proliferation" RELATED [] is_a: DDPHENO:0001529 ! aberrant regulation of vegetative growth created_by: pfey creation_date: 2013-02-15T10:44:33Z [Term] id: DDPHENO:0001531 name: abolished negative regulation of vegetative growth def: "Complete inability to negatively regulate vegetative growth." [DDB:pf] synonym: "abolished negative regulation of asexual reproduction" EXACT [] synonym: "abolished negative regulation of cell proliferation" RELATED [] is_a: DDPHENO:0001530 ! aberrant negative regulation of vegetative growth created_by: pfey creation_date: 2013-02-15T10:46:20Z [Term] id: DDPHENO:0001532 name: aberrant positive regulation of vegetative growth def: "Deviation from the normal, usual, or expected events during the positive regulation of vegetative growth." [DDB:pf] synonym: "aberrant positive regulation of asexual reproduction" EXACT [] synonym: "aberrant positive regulation of cell proliferation" RELATED [] is_a: DDPHENO:0001529 ! aberrant regulation of vegetative growth created_by: pfey creation_date: 2013-02-15T11:00:01Z [Term] id: DDPHENO:0001533 name: abolished positive regulation of vegetative growth def: "Complete inability to positively regulate vegetative growth." [DDB:pf] synonym: "abolished positive regulation of asexual reproduction" EXACT [] synonym: "abolished positive regulation of cell proliferation" RELATED [] is_a: DDPHENO:0001532 ! aberrant positive regulation of vegetative growth created_by: pfey creation_date: 2013-02-15T11:01:54Z [Term] id: DDPHENO:0001534 name: increased lysosomal pH def: "Quantitative increase in lysosomal pH." [DDB:pf] synonym: "increased lysosomal lumen pH elevation" EXACT [] is_a: DDPHENO:0001237 ! aberrant lysosome organization created_by: pfey creation_date: 2013-03-25T10:52:45Z [Term] id: DDPHENO:0001535 name: decreased protein processing in phagocytic vesicle def: "Reduction in extent, amount, or degree of phagosomal protein processing." [DDB:pf] synonym: "decreased phagosomal proteolysis" EXACT [] synonym: "decreased protein maturation by proteolysis in phagosome" EXACT [] is_a: DDPHENO:0001006 ! aberrant phagocytosis created_by: pfey creation_date: 2013-03-25T11:01:42Z [Term] id: DDPHENO:0001536 name: aberrant nucleus organization def: "Deviation from the normal, usual, or expected events during nucleus organization." [DDB:pf] is_a: DDPHENO:0001043 ! aberrant organelle organization created_by: pfey creation_date: 2013-03-27T14:34:35Z [Term] id: DDPHENO:0010000 name: Dicty Phenotypes def: "Phenotypes describing mutations in Dictyostelium." [DDB:pf]