format-version: 1.2 data-version: releases/2024-02-20 subsetdef: attribute_slim "" subsetdef: cell_quality "" subsetdef: cellxgene_subset "" subsetdef: common_anatomy "" subsetdef: efo_slim "" subsetdef: gocheck_do_not_annotate "" subsetdef: gocheck_do_not_manually_annotate "" subsetdef: goslim_agr "" subsetdef: goslim_candida "" subsetdef: goslim_chembl "" subsetdef: goslim_drosophila "" subsetdef: goslim_flybase_ribbon "" subsetdef: goslim_generic "" subsetdef: goslim_metagenomics "" subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" subsetdef: goslim_prokaryote "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology "" subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam "" subsetdef: mpath_slim "" subsetdef: non_informative "" subsetdef: pheno_slim "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" subsetdef: uberon_slim "" subsetdef: ubprop:upper_level "" subsetdef: upper_level "" subsetdef: value_slim "" subsetdef: vertebrate_core "" ontology: ecao property_value: http://purl.org/dc/elements/1.1/description "None" xsd:string property_value: http://purl.org/dc/elements/1.1/title "Echinoderm Anatomy and Development Ontology" xsd:string property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/3.0/ [Term] id: BFO:0000001 name: entity property_value: BFO:0000179 "entity" xsd:string property_value: BFO:0000180 "Entity" xsd:string property_value: IAO:0000112 "Julius Caesar" xsd:string property_value: IAO:0000112 "the Second World War" xsd:string property_value: IAO:0000112 "Verdi’s Requiem" xsd:string property_value: IAO:0000112 "your body mass index" xsd:string property_value: IAO:0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string property_value: IAO:0000116 "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", http://www.w3.org/2000/01/rdf-schema#seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"} property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 ! continuant property_value: BFO:0000179 "continuant" xsd:string property_value: BFO:0000180 "Continuant" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string property_value: IAO:0000116 "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"} property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] is_a: BFO:0000001 ! entity relationship: part_of BFO:0000003 ! occurrent property_value: BFO:0000179 "occurrent" xsd:string property_value: BFO:0000180 "Occurrent" xsd:string property_value: IAO:0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string property_value: IAO:0000116 "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string property_value: IAO:0000116 "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"} property_value: IAO:0000116 "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"} property_value: IAO:0000589 "processual entity (BFO)" xsd:string property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"} property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000004 name: independent continuant def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} comment: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! characteristic disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000004 ! independent continuant property_value: BFO:0000179 "ic" xsd:string property_value: BFO:0000180 "IndependentContinuant" xsd:string property_value: IAO:0000112 "a chair" xsd:string property_value: IAO:0000112 "a heart" xsd:string property_value: IAO:0000112 "a leg" xsd:string property_value: IAO:0000112 "a molecule" xsd:string property_value: IAO:0000112 "a spatial region" xsd:string property_value: IAO:0000112 "an atom" xsd:string property_value: IAO:0000112 "an orchestra." xsd:string property_value: IAO:0000112 "an organism" xsd:string property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string property_value: IAO:0000112 "the interior of your mouth" xsd:string property_value: IAO:0000589 "anatomical entity (BFO)" xsd:string property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000015 name: process def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} comment: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. is_a: BFO:0000003 ! occurrent relationship: part_of BFO:0000015 ! process property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string property_value: IAO:0000112 "a process of meiosis" xsd:string property_value: IAO:0000112 "a process of sleeping" xsd:string property_value: IAO:0000112 "the course of a disease" xsd:string property_value: IAO:0000112 "the flight of a bird" xsd:string property_value: IAO:0000112 "the life of an organism" xsd:string property_value: IAO:0000112 "your process of aging." xsd:string property_value: IAO:0000116 "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role property_value: BFO:0000179 "disposition" xsd:string property_value: BFO:0000180 "Disposition" xsd:string property_value: IAO:0000112 "an atom of element X has the disposition to decay to an atom of element Y" xsd:string property_value: IAO:0000112 "certain people have a predisposition to colon cancer" xsd:string property_value: IAO:0000112 "children are innately disposed to categorize objects in certain ways." xsd:string property_value: IAO:0000112 "the cell wall is disposed to filter chemicals in endocytosis and exocytosis" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type." xsd:string property_value: IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: IAO:0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000017 name: realizable name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! characteristic disjoint_from: BFO:0000019 ! quality relationship: part_of BFO:0000017 ! realizable entity property_value: BFO:0000179 "realizable" xsd:string property_value: BFO:0000180 "RealizableEntity" xsd:string property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string property_value: IAO:0000112 "the function of your reproductive organs" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000019 name: quality is_a: BFO:0000020 ! characteristic relationship: part_of BFO:0000019 ! quality property_value: BFO:0000179 "quality" xsd:string property_value: BFO:0000180 "Quality" xsd:string property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string property_value: IAO:0000112 "the color of a tomato" xsd:string property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string property_value: IAO:0000112 "the mass of this piece of gold." xsd:string property_value: IAO:0000112 "the shape of your nose" xsd:string property_value: IAO:0000112 "the shape of your nostril" xsd:string property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000020 name: characteristic name: specifically dependent continuant def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} comment: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: has_part BFO:0000020 ! characteristic relationship: part_of BFO:0000020 ! characteristic property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the shape of this hole." xsd:string property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string property_value: IAO:0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"} property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl property_value: seeAlso https://github.com/OBOFoundry/COB/issues/65 xsd:string property_value: seeAlso https://github.com/oborel/obo-relations/pull/284 xsd:string [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: BFO:0000017 ! realizable entity property_value: BFO:0000179 "role" xsd:string property_value: BFO:0000180 "Role" xsd:string property_value: IAO:0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married." xsd:string property_value: IAO:0000112 "the priest role" xsd:string property_value: IAO:0000112 "the role of a boundary to demarcate two neighboring administrative territories" xsd:string property_value: IAO:0000112 "the role of a building in serving as a military target" xsd:string property_value: IAO:0000112 "the role of a stone in marking a property boundary" xsd:string property_value: IAO:0000112 "the role of subject in a clinical trial" xsd:string property_value: IAO:0000112 "the student role" xsd:string property_value: IAO:0000116 "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives." xsd:string property_value: IAO:0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: IAO:0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000031 name: generically dependent continuant def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} comment: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. is_a: BFO:0000002 ! continuant relationship: part_of BFO:0000031 ! generically dependent continuant property_value: BFO:0000179 "gdc" xsd:string property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition property_value: BFO:0000179 "function" xsd:string property_value: BFO:0000180 "Function" xsd:string property_value: IAO:0000112 "the function of a hammer to drive in nails" xsd:string property_value: IAO:0000112 "the function of a heart pacemaker to regulate the beating of a heart through electricity" xsd:string property_value: IAO:0000112 "the function of amylase in saliva to break down starch into sugar" xsd:string property_value: IAO:0000116 "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc." xsd:string property_value: IAO:0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: IAO:0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant property_value: BFO:0000179 "material" xsd:string property_value: BFO:0000180 "MaterialEntity" xsd:string property_value: IAO:0000112 "a flame" xsd:string property_value: IAO:0000112 "a forest fire" xsd:string property_value: IAO:0000112 "a human being" xsd:string property_value: IAO:0000112 "a hurricane" xsd:string property_value: IAO:0000112 "a photon" xsd:string property_value: IAO:0000112 "a puff of smoke" xsd:string property_value: IAO:0000112 "a sea wave" xsd:string property_value: IAO:0000112 "a tornado" xsd:string property_value: IAO:0000112 "an aggregate of human beings." xsd:string property_value: IAO:0000112 "an energy wave" xsd:string property_value: IAO:0000112 "an epidemic" xsd:string property_value: IAO:0000112 "the undetached arm of a human being" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string property_value: IAO:0000116 "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string property_value: IAO:0000116 "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: CARO:0000000 name: anatomical entity namespace: spatial def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH] [Term] id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 xref: FMA:68646 xref: GO:0005623 xref: KUPO:0000002 xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0043226 ! organelle relationship: has_part GO:0005634 {gci_filler="PATO:0001908", gci_relation="has_characteristic"} ! nucleus relationship: has_part GO:0005634 {gci_filler="PATO:0001407", gci_relation="has_characteristic"} ! nucleus relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: CL:0000225 name: anucleate cell def: "A cell that lacks a nucleus." [FB:ma] synonym: "non-nucleated cell" EXACT [] xref: FMA:68647 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001405 ! anucleate disjoint_from: CL:0002242 ! nucleate cell relationship: has_characteristic PATO:0001405 ! anucleate [Term] id: CL:0000226 name: single nucleate cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001407 ! mononucleate relationship: has_characteristic PATO:0001407 ! mononucleate [Term] id: CL:0000227 name: binucleate cell is_a: CL:0000228 ! multinucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001406 ! binucleate relationship: has_characteristic PATO:0001406 ! binucleate [Term] id: CL:0000228 name: multinucleate cell def: "A cell with more than one nucleus." [FB:ma] synonym: "syncitium" EXACT [] synonym: "syncytial cell" EXACT [] synonym: "syncytium" EXACT [] xref: AEO:0000203 xref: WBbt:0008074 is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0001908 ! multinucleate relationship: has_characteristic PATO:0001908 ! multinucleate [Term] id: CL:0000255 name: eukaryotic cell subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000521 name: fungal cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000000 ! cell intersection_of: only_in_taxon NCBITaxon:4751 ! Fungi relationship: only_in_taxon NCBITaxon:4751 ! Fungi [Term] id: CL:0002242 name: nucleate cell def: "A cell containing at least one nucleus." [GOC:tfm] xref: FMA:67513 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: has_characteristic PATO:0002505 ! nucleated property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T03:32:33Z [Term] id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation relationship: capable_of GO:0030154 ! cell differentiation [Term] id: ECAO:00000000 name: root node [Term] id: ECAO:0000010 name: life cycle period [Term] id: ECAO:0000020 name: gametogenesis def: "Biological process during which certain cells of a female or male individual (parent) are transformed into specialized reproductive cells (gametes) that will initiate development of a progeny individual (offspring) upon fertilization." [] is_a: UBERON:0000105 ! life cycle stage relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000030 name: oogenesis period def: "Period during which female gametes (or oocytes, or eggs) develop and mature from primordial female germ cells to generate cells competent to further development upon fertilization by a mature spermatozoid." [] synonym: "ovogenesis period" EXACT [] relationship: part_of ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000040 name: previtellogenic primary oocyte stage def: "A female gamete that is small in size, i.e. about 10 microm in diameter, and that is at the previtellogenic stage." [] relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000050 name: not fully grown oocyte stage def: "A developing female gamete that started growing in size by accumulation of yolk proteins. At this stage, it is characterized by the presence of a large nucleus, the germinal vesicle, which contains a prominent nucleolus and occupies most of the cytoplasm." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000040 ! previtellogenic primary oocyte stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000060 name: fully grown oocyte with centered germinal vesicle stage def: "A developing female gamete that has reached its full size. It has grown up to ten times its original size, i.e. 80 to 100microm. It also displays a large germinal vesicle that is centered, but it is still not competent for fertilization." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000050 ! not fully grown oocyte stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000070 name: fully grown oocyte with off-centered germinal vesicle stage def: "A developing female gamete that has reached its full size and in which the germinal vesicle has moved asymmetrically to the cell periphery. The germinal vesicle is now close to the animal pole." [] synonym: "primary oocyte" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000080 name: fully grown oocyte with no nucleus stage def: "A developing female gamete in which the germinal vesicle has broken down. The germinal vesicle is no longer visible. However, the female gamete is still not mature. It is undergoing meiotic maturation, extruding successively a first and a second polar body." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000090 name: mature oocyte stage def: "A mature female gamete that has achieved its meiotic maturation and in which the female pronucleus is visible. The mature oocyte is arrested in G1 phase and its average size is 80 to 100 µm. It is surrounded by a transparent jelly coat that is about 30 µm thick. It is competent to fertilization and it is located in the female gonad where it may be stored for weeks to months before its release in sea water by spawning. In the P. lividus species, the mature female gametes are characterized by the presence of pigment granules concentrated in a subequatorial band. This band is classically called the pigment band and allows to visualize the first embryonic axis, i.e. the animal-vegetal axis, which is perpendicular to the band." [] synonym: " spawned egg" EXACT [] synonym: "unfertilized egg" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: part_of ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000100 name: spermatogenesis period def: "Period during which male gametes (or spermatozoa, or spermatozoid) develop and mature from primordial male germ cells to generate cells competent to further development upon fertilization of a mature oocyte." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000030 ! oogenesis period relationship: part_of ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000110 name: developing spermatozoa stage def: "A developing, immature male gamete undergoing mitosis and meiosis to ultimately produce mature spermatozoa." [] synonym: "spermatid" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000120 name: mature spermatozoid stage def: "A mature male gamete that is composed of a head, encompassing a compact nucleus, a neck, a middle piece, and a tail (or flagellum) that propels it towards the oocyte upon spawning." [] synonym: " spermatozoa" EXACT [] synonym: "sperm" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000110 ! developing spermatozoa stage relationship: part_of ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000130 name: embryogenesis def: "Biological process during which the embryo forms. This process starts with the fertilization of a mature oocyte by a mature spermatozoid. It is characterized by a succession of rapid mitotic divisions with no significant growth, but with axis establishment and cellular differentiation, thereby leading to the development of a multicellular embryo." [] is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000020 ! gametogenesis relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000140 name: 1-cell stage def: "A fertilized egg, right after fertilization. The embryo is characterized morphologically by the fact that it is a single diploid cell surrounded by a fertilization envelope. This stage corresponds to an embryo of age 0 hour post-fertilization." [] synonym: " fertilized egg" EXACT [] synonym: "zygote stage" EXACT [] xref: UBERON:0000106 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000100 ! spermatogenesis period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000150 name: cleavage period def: "Period during which the fertilized egg undergoes a succession of rapid cell divisions with no significant growth." [] xref: UBERON:0000107 is_a: BFO:0000003 ! occurrent relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000160 name: 2-cell stage def: "An embryo that is composed of two cells and is surrounded by a fertilization envelope. The first cleavage plane took place meridionally (i.e. along the animal-vegetal axis), thereby generating two blastomeres of equal size, each containing both animal and vegetal cytoplasm." [] synonym: "2c" EXACT [] xref: UBERON:0007232 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000170 name: 4-cell stage def: "An embryo that is composed of four cells and is surrounded by a fertilization envelope. The second cleavage plane was meridional and perpendicular to the first one, thereby producing four blastomeres of equal size, each containing both animal and vegetal cytoplasm." [] synonym: "4c" EXACT [] xref: UBERON:0007233 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000180 name: 8-cell stage def: "An embryo that is composed of eight cells and is surrounded by a fertilization envelope. The third cleavage took place perpendicular to the first two cleavage planes and was equatorial. It thus generated an animal and a vegetal hemisphere each composed of a quartet of four cells of equal volume." [] synonym: "8c" EXACT [] xref: UBERON:0007236 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000170 ! 4-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000190 name: 16-cell stage def: "An embryo that is composed of 16 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: although the fourth cleavage occurred simultaneously in all cells, the pattern of cell division differed in the animal and vegetal blastomeres. In the animal hemisphere the four cells divided meridionally, producing eight blastomeres of equal volume arrayed in a single tier. These cells are called the mesomeres. In the vegetal hemisphere, the four cells underwent an unequal, equatorial cleavage, producing a tier of four large cells, the macromeres, and a tier of four small cells, the micromeres, located at the vegetal pole. At the 16-cell stage, the embryo is hence composed of three groups of cells with distinct sizes. In most sea urchin species,this is the first morphological indication of the animal-vegetal axis." [] synonym: "16c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000200 name: 28-cell stage def: "An embryo that is composed of 28 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: In most sea urchin species, the fifth cleavage signed the end of cell division synchrony, with the mesomeres and macromeres dividing prior to the micromeres with a significant time difference. In the animal hemisphere, the mesomeres underwent an equal and equatorial cleavage, giving rise to two animal cell tiers, each composed of eight blastomeres of equal size: the an1 tier located at the animal pole and the an2 tier located below an1. In parallel, the macromeres divided meridionally, forming a ring of eight cells of equal volume located below the an2 tier. At that stage, the micromeres have not yet divided and are still at a number of four cells." [] synonym: "28c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000210 name: 32-cell stage def: "An embryo that is composed of 32 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: The micromeres have undergone a fifth cleavage (and this has occurred prior to a subsequent division of the other cells). This cleavage was unequal and equatorial, thereby producing four large micromeres and four small micromeres, the smallest cells still marking the vegetal pole." [] synonym: "32c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000220 name: 56-cell stage def: "An embryo that is composed of 56 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: In the animal hemisphere, cells of the an1 and an2 tiers underwent an additional meridional division, producing tiers composed of 16 cells. The macromeres divided equatorially and equally, generating two vegetal cell tiers, each composed of 8 cells of equal volume, namely the veg1 tier (located below an2) and the veg2 tier (located below veg1 and above the large micromeres). At that stage, the large and small micromeres (4 cells each) have not undergone yet a sixth division." [] synonym: "56c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000230 name: 60-cell stage def: "An embryo that is composed of 60 cells and is surrounded by a fertilization envelope. Note for euechinoid indirect developers: The large micromeres have achieved a sixth cleavage, which was meridional, thereby generating a ring of 8 cells. At that stage, from the animal to the vegetal pole, the embryo is composed of: 16 an1-cells, 16 an2-cells, 8 veg1-cells, 8 veg2-cells, 8 large micromeres and 4 small micromeres." [] synonym: "60c" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0000150 ! cleavage period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000240 name: blastula period def: "Period during which the embryo is transformed into a hollow sphere that is one cell layer thick and encompasses a central, fluid-filled cavity called the blastocoel. During this period, every cell of the embryo is in contact on the inside with the blastocoel and on the outside with the hyaline layer." [] xref: UBERON:0000307 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000150 ! cleavage period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000250 name: very early blastula stage def: "The embryo is composed of 110-120 cells, as most blastomeres have completed an additional mitotic division after the 60-cell stage. The embryo is surrounded by a fertilization envelope. All cells are about the same size and there are no obvious morphological indications of embryonic polarity or embryonic territories. All cells have begun to acquire apico-basal polarity, and the embryo is beginning to transform into a hollow sphere with a wall that is one cell layer thick and a fluid-filled cavity (the blastocoel) in the center. Note for euechinoid indirect developers: the micromere progeny divide more slowly than other cells of the embryo. Molecular labelling typically indicates the presence of 8 large micromere descendants and 4 small micromeres at this stage ." [] synonym: " 120-cell stage" EXACT [] synonym: " B1" EXACT [] synonym: "vEB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000260 name: early blastula stage def: "The embryo is composed of slightly more than 200 cells, as most blastomeres have completed an additional mitotic division after the very early blastula stage. The embryo is surrounded by a fertilization envelope. The embryo remains spherical and one cell layer thick, and the blastocoel has expanded slightly since the very early blastula stage, without increasing though the size of the embryo. The synchrony of cell divisions between animal and vegetal cell tiers, as well as within cell tiers, is becoming less pronounced. Note for euechinoid indirect developers: Molecular labeling typically indicates the presence of 16 large micromere descendants and 4 small micromeres at this stage ." [] synonym: " B2" EXACT [] synonym: "EB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000270 name: mid-blastula stage def: "The embryo is composed of about 300 cells and is surrounded by a fertilization envelope. Cell divisions are less synchronous than at earlier stages. The cells have flattened slightly on their inner (basal) surface, further contributing to the enlargement of the blastocoel. In some species, cells have started to form cilia on their outer surface. The embryo is still spherical and does not display any obvious morphological landmarks that indicate the primary or secondary embryonic axes. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 16 to 32 large micromere descendant cells and 4 to 8 small micromere descendants at this stage ." [] synonym: " B3" EXACT [] synonym: " midB" EXACT [] synonym: "mid-B" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000280 name: late blastula stage def: "The embryo is composed of about 400 cells and is surrounded by a fertilization envelope. The embryo is still spherical but the wall is thinner and smoother than at previous stages. The vegetal plate has not formed. Many cells are ciliated, and in some species (e.g. P. lividus) the embryo has begun to rotate within the fertilization envelope, while in others (e.g. S. purpuratus) it is still non-motile. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 32 large micromere descendants and 4 to 8 small micromere descendants at this stage ." [] synonym: " B4" EXACT [] synonym: " LB" EXACT [] synonym: " pre-HB" EXACT [] synonym: " prehatched blastula" EXACT [] synonym: "Late-B" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000290 name: hatched blastula stage def: "The embryo is composed of about 800 cells and is surrounded by a fertilization envelope. The fertilization envelope has started to break down due to the secretion by ectodermal cells of the hatching enzyme, a metalloprotease that digests the fertilization envelope and frees the embryo. The vegetal plate has not formed. The embryo rotates within the envelope or swims away as soon as it is free. At the animal pole, a tuft of long and immotile cilia has started growing." [] synonym: " B5" EXACT [] synonym: " very late blastula stage" EXACT [] synonym: "HB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000300 name: swimming blastula stage def: "The embryo has hatched from the fertilization envelope and swims freely. It is still a hollow sphere that is one cell layer thick, but the cells constituting the vegetal plate (i.e. located at the vegetal pole) have started thickening along the apico-basal axis, thereby creating a morphological landmark that enables orienting the embryo along the animal-vegetal axis. In addition, at the animal pole, the apical tuft composed of long and immotile cilia has continued expending." [] synonym: "SB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000290 ! hatched blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000310 name: late swimming blastula stage def: "The embryo has started elongated along the animal-vegetal axis. Its vegetal region has further continued to thicken and it is marked by a characteristic 'V' shape formed by the blastocoel at the level of the cells constituting the vegetal plate, thereby pointing to the vegetal pole. At the animal pole, the embryo is characterized by the presence of an apical tuft." [] synonym: "late-SB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000300 ! swimming blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000320 name: gastrula period def: "Period during which complex and coordinated cellular movements take place and ultimately generate a three-layered embryo with inner tissues. A portion of cells will ingress, invaginate and/or migrate within the embryo and form the two inner layers (i.e. the endoderm and the mesoderm). The cells that remained outside will instead spread over the whole surface of the embryo and form the outer layer (i.e. the ectoderm)." [] xref: UBERON:0000109 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000240 ! blastula period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000330 name: mesenchyme blastula phase def: "The phase during which skeletogenic primary mesenchyme cells (PMCs) move from the vegetal plate into the blastocoel (ingress) but before the vegetal plate has started to invaginate." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0000320 ! gastrula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000340 name: early mesenchyme blastula stage def: "The vegetal plate is apparent and skeletogenic primary mesenchyme cells (PMCs) are in the process of ingression, a type of epithelial–mesenchymal transition (EMT). The epithelial wall of the embryo has thickened at the animal pole, where a tuft of long, non-motile cilia has formed." [] synonym: "eMB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000350 name: mid-mesenchyme blastula stage def: "All skeletogenic primary mesenchyme cells (PMCs) have ingressed into the blastocoel, leaving behind a reformed vegetal plate containing at its center the 8 small micromere descendants surrounded by non-skeletogenic mesoderm cells. The PMCs are organized in a mound on the vegetal plate but have not begun to disperse. The thickened apical pole domain with its tuft of long, non-motile cilia is still apparent." [] synonym: "mid-MB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000360 name: late mesenchyme blastula stage def: "The skeletogenic primary mesenchyme cells (PMCs) have migrated away from the vegetal plate by extending filopodia and moving along the blastocoel wall. The vegetal plate has flattened but has not started to invaginate. The apical pole domain still bears an apical tuft of long, non-motile cilia." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000350 ! mid-mesenchyme blastula stage relationship: part_of ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000370 name: invagination phase def: "Period during which the inpocketing and elongation of the archenteron takes place." [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0000320 ! gastrula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000380 name: blastopore formation stage def: "The embryo is characterized morphologically by a slight invagination of the vegetal plate and the dispersal of the skeletogenic primary mesenchyme cells (PMCs) along the blastocoel wall at the periphery of the invaginating region. The PMCs are just beginning to adopt a characteristic, ring-like arrangement near the equator of the embryo. Within the vegetal plate, the peripheral non-skeletogenic mesoderm cells have started to indent, undergoing important cell shape changes, but the center of the vegetal plate (composed of small micromeres) has not started to elevate. Invagination has generated the blastopore (an opening that will give rise to the larval anus) as well as the anterior portion of the archenteron (a region that will give rise to the coelomic pouches). At the animal pole, the apical pole domain is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " blastopore gastrula stage" EXACT [] synonym: "blasto-G" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000360 ! late mesenchyme blastula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000390 name: early gastrula stage def: "The embryo is mainly characterized morphologically by the presence in the blastocoel of a small archenteron (i.e. primitive digestive tract) that is about a third of its finally size. Following the initial invagination of the vegetal plate, the archenteron has slightly been extended, within the blastocoel, by the subsequent invagination of additional non-skeletogenic mesoderm cells and of some endoderm cells. In parallel, the skeletogenic mesenchyme cells (or SM cells, primary mesenchyme cells or PMC) have by now started migrating along the blastocoel wall, towards the animal pole, thereby creating two lateral chains (one left and one right), while around the developing archenteron, they have gathered into two ventrolateral clusters separated by an oral (or ventral) and an aboral (or dorsal) chain defined by the remaining skeletogenic mesenchyme cells. Within the oral and aboral skeletogenic mesenchyme chains, the cells have further started to fuse to form syncytial filopodial cables within which skeletal calcification will subsequently take place. At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " EG" EXACT [] synonym: "eG" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000400 name: mid-gastrula stage def: "The embryo is mainly characterized morphologically by the presence of an archenteron (i.e. primitive digestive tract) that has reached one-half its way into the blastocoel. A second phase of archenteron elongation has taken place by invagination of additional cells into the blastocoel, by cell division or by convergent-extension movements depending on the sea urchin species. Non-skeletogenic mesoderm cells that are present at the tip of the archenteron have further started ingressing into the blastocoel, generating the non-skeletogenic mesenchyme cells (or NSM cells, secondary mesenchyme cells or SMC). The oral ectoderm has also started to flatten and to become thicker, providing the first morphological indicator of the oral-aboral (or ventro-dorsal) axis of the embryo. As a consequence the oral chain formed by a portion of the skeletogenic mesenchyme cells has also flattened. Finally, skeletal calcification has further begun within the skeletogenic mesenchyme ventrolateral clusters, marked by the presence of the first calcified structures, which appear as small dots at that stage. At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " mid-G" EXACT [] synonym: "G" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000410 name: late gastrula stage def: "The embryo is mainly characterized morphologically by the presence in the blastocoel of a fully extended archenteron (i.e. primitive digestive tract) that has now reached the roof of the blastocoel. The third and last extension phase of the archenteron has been ensured by pulling forces exerted by non-skeletogenic mesoderm cells that are still present at the tip of the archenteron. These cells have produced filopodia that extended towards the animal pole, attached the wall, and then shortened, thereby pulling up the archenteron. In some sea urchin species, this pulling force is already orienting the tip of the archenteron towards the oral ectoderm, where the future mouth of the larvae will form. In parallel, in the blastocoel, additional non-skeletogenic mesoderm cells continued ingressing from the tip of the archenteron and the skeletal calcified structures present in the skeletogenic mesenchyme ventrolateral clusters have further grown, forming now the primary triradiate skeletal rudiments (or spicules). At the animal pole, the animal neuroectoderm territory is still marked by an enlarged epithelium bearing long and immotile cilia." [] synonym: " late-G" EXACT [] synonym: "LG" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0000370 ! invagination phase property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000420 name: organogenesis period def: "To be written" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000320 ! gastrula period relationship: part_of ECAO:0000130 ! embryogenesis property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000430 name: prism stage def: "The embryo is mainly characterized morphologically by a typical triangular shape, the beginning of the tripatition of the digestive tract and the presence of pigmented cells. The oral (or ventral) ectoderm has by now even more flattened, making an almost perfect right angle with the blastoporal side of the embryo. By contrast, on the opposite side, the aboral (or dorsal) ectoderm has round up and slightly elongated, thereby forming the primitive apex of the future larvae. These changes have conferred the embryo a typical and easy recognizable triangular shape. In the oral ectoderm, a small depression has further appeared, called the stomodeum, which will later fuse with the tip of the archenteron to form the mouth. In the blastocoel, the digestive tract has also by now bended toward the stomodeum and started to become tripartite. The cardiac sphincter has started forming, separating the future esophagus from the future stomach. The triradiate spicules have also continued elongating, thereby forming by now, towards the animal pole, the right and left dorsoventral connecting rods, towards the apex, the body rods, and along the vegetal, oral ectoderm the left and right ventral transverse rods. Moreover, some non-skeletogenic mesenchyme cells (or NSM cells, secondary mesenchyme cells or SMC) have started becoming pigmented and inserted into the aboral ectoderm. These cells represent part of the future immune system of the larvae along with other blastocoelar cells that are present in the blastocoel around the gut. In the vicinity of the future esophagus, other non-skeletogenic mesoderm descendant cells along with some endoderm cells have further arranged to form a single unpaired coelomic pouch. At the animal pole, the apical pole domain has also started to flatten making the embryo look like a square when viewed from the oral side, and it still arbors a tuft a long and immotile cilia. Finally, within the apical pole domain, but not yet in the ciliary band, molecular labeling surveys also start by this stage to reveal the presence of differentiating neuronal cells." [] synonym: " D" EXACT [] synonym: "Pr" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000370 ! invagination phase relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000440 name: larval development is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000130 ! embryogenesis relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000450 name: early feeding larva period def: "Biological process during which the specific outcome is the progression of a free-living larva before the development of the adult. Indirect development represents the mainstream developmental mode of metazoans. This process usually starts with the emergence of a larva that is planktonic and stops at the end of metamorphosis once the animal assumes adult characters." [] xref: UBERON:0000069 is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000420 ! organogenesis period relationship: part_of ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000460 name: early pluteus larva stage def: "The embryo is by now a fully formed pluteus larva. The mouth has opened and the digestive tract is becoming functional. On the ventral side, the mouth is surrounded anteriorly by an oral hood and posteriorly by two postoral arms. On the dorsal side, the apex has lengthened. The skeleton has indeed continued extending, expending the dorsoventral connecting rods, the body rods, and the ventral transverse rods as well as developing the anterolateral rods and the postoral rods. Within the larva, the tripartition of the digestive tract has further progressed. The cardiac sphincter is now fully formed in between the esophagus and the stomach, and the pyloric sphincter in between the stomach and the intestine and the anal sphincter at the level of the anus have also started forming. Around the esophagus, the coelomic pouch has further developed into two bilobed sacs (or pouches), one on each side of the digestive tract. Finally, within the apical pole domain, as well as within the ciliary band, differentiated neurons with their extended axons can also now be distinguished by immunostaining. In parallel, the apical tuft of long and immotile cilia remains discernable at the tip of the oral hood, while in parallel the ciliary band has further started growing a concentrated number of intermediate size motile cilia, which will be used by the larva to swim directionally." [] synonym: " 2-arm pluteus stage" EXACT [] synonym: " early pluteus stage" EXACT [] synonym: "Eplut" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000430 ! prism stage relationship: part_of ECAO:0000450 ! early feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000470 name: 4-arm pluteus larva stage def: "The 4-arm pluteus larva is mainly characterized morphologically by the presence, on the ventral side, of four extended arms (two anterolateral arms at the level of the oral hood and two postoral arms) and on the dorsal side by a sleeked apex. The larva now possesses a completely tripartite and functional digestive tract composed of an esophagus, a stomach, and an intestine, respectively limited by a cardiac sphincter, a pyloric sphincter, and an anal sphincter. Around the esophagus, the right and left coelomic pouches have further started to grow in size and elongate. The first morphological indicator of a left-right asymmetry becomes apparent at that stage, the left coelomic pouch being slightly more elongated than the right one. Furthermore, a thin protrusion of non-skeletogenic mesenchyme cells can be seen extending from the left coelomic pouch to the anterior ectoderm. This is the primary pore canal, which opens to the exterior environment by the hydropore. The larva further now possesses, all around the esophagus, a network of contractile muscles allowing it to swallow and feed. Finally, the apical tuft previously observed at the animal pole has by now disappeared, leaving behind only the concentrated stretch of intermediate size cilia borne by the ciliary band." [] synonym: " P" EXACT [] synonym: " Plut" EXACT [] synonym: " Plut4a" EXACT [] synonym: " pluteus larva" EXACT [] synonym: "Pluteus" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0000450 ! early feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000480 name: late feeding larva period def: "To be written" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000450 ! early feeding larva period relationship: part_of ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000490 name: 6-arm pluteus larva stage def: "The 6-arm pluteus larva is mainly characterized morphologically by the presence, on the ventral side, of six arms, and by the development, on the anterior midline of the esophagus, of the dorsal arch. The larva has indeed extended on the ventral side two additional posterodorsal arms and has developed on the anterior side an additional skeletal element called the dorsal arch. In addition, at the basis of the postoral and posterodorsal arms, four small patches of ciliary band have by now cut off and migrated toward the apex, forming four patches of ciliated structures called the epaulettes (one posterior and one anterior pair). The nervous system of the larva has also become more complex with cell bodies and axons being present all along the arms and for the latter as well throughout the apex. The left and right coelomic pouches have continued to elongate on each side of the digestive tract. As a note this stage is relatively fleeting." [] synonym: "Plut6a" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000500 name: 8-arm pluteus larva stage def: "The 8-arm pluteus larva is mainly characterized morphologically by the presence on the ventral side of the larva of eight arms and by the development within the larva, on the left side of the stomach, of the adult rudiment. This stage is relatively long. It includes distinct changes occurring to the larva as well as within the larva, although the larva consistently exhibits 8 arms. In addition, it should be highlighted that the sequence of events taking place at the level of the larva compared to that occurring on the left side of the stomach to form the rudiment are heterochronic, meaning that differences are observed among individuals in the relative timing of these events. From the larval point of view, at that stage, on the anterior side, the dorsal arch has extended out of the oral hood, thereby forming two additional arms above the mouth, i.e. the preoral arms. In parallel, across the apex, the epaulettes have continued developing, thereby generating four large structures rich in cilia and perpendicular to the ventro-dorsal axis. At the tip of the apex, the suture of the body rods has also eventually ruptured, considerably enlarging the larval apex and reducing the angle between the postoral and posterodorsal arms. In parallel, inside the larva, the left coelomic pouch has also by now been partitioned into three parts: the axocoel (upper part, close to the esophagus), the hydrocoel (middle part) and the somatocoel (lower part, next to the stomach). Likewise, on the opposite side, the right coelomic pouch has also been partitioned into a right axohydrocoel and a right somatocoel, although the right axohydrocoel remains in a rudimentary state compared to its left counterparts. In addition, at the basis of the posterodorsal arm on the left side, a small portion of the ectoderm has thickened, invaginated, and came into contact with the left hydocoel. This structure is called the vestibule and together with the left hydrocoel and the left stomatocoel they have further subsequently fused to form the adult rudiment. The formation of the rudiment has overall taken some time, giving rise first to a pentaradial disc and then to a pentaradial complex structure harboring podia (i.e. tube feet) and spines. In parallel, on the right size of the larva, a variable number of pedicellariae (one to four) and endoskeletal elements (i.e. the five genital plates) have further formed, which will also later contribute to the composition of the adult body." [] synonym: "Plut8a" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000510 name: competent pluteus larva stage def: "The competent pluteus larva is mainly characterized morphologically by the presence, on the ventral size, of still 8 arms and by the presence on the left side of the stomach of the rudiment that is now the size of or even bigger than the stomach. The rudiment further harbors by now five long primary podia (i.e. tube feet), five quartets of definitive spines located between the primary podia and five pairs of immature spines at the basis of the primary podia, while on the opposite side, i.e. on the right side of the larva, five to seven immature spines have further developed, supported by the genital plates, along with one to four pedicaellariae. At the level of the larva, in parallel, the anterior and posterior pairs of epaulettes have also considerably increased in size by now and even fused dorsally to the hydropore and to the anus respectively, thereby leaving exempt of cilia two lateral fields in between them. At the center of the left lateral field, the vestibular roof has also by now ruptured and this opening has created the vestibular pore, through which some primary podia of the rudiment protrude outside the larva and scrutinize the substrate looking for the adequate cues to begin metamorphosis. At that stage, the larva is thus exhibiting a typical substrate-test behavior, going to the sea bottom and scrutinizing the substrate. This behavior is characteristic of a larva named competent to metamorphosis, which it will accomplish providing that it is adequately stimulated by environmental factors." [] synonym: " Cpt8a" EXACT [] synonym: "cPlut" EXACT [] xref: UBERON:0008265 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000520 name: metamorphic larva stage def: "The metamorphic larva stage consists essentially of the evagination of the echinoid rudiment. It is characterized by the execution of conspicuous and relatively abrupt physical changes that take place quite quickly, in about one hour, and during which the planktonic larva is transformed into a benthic juvenile. At that stage, the larva is settled on the substrate and is firmly attached to it by the primary podia of the rudiment. The ectodermal epithelium of its arms has started to collapse, making the spicules supporting the larval arms piercing through the epidermis. The larval mouth and anus have further closed, while in parallel, within the larva, the rudiment spines have lifted up thereby distending the vestibular wall and wide opening the vestibular pore. Following these movements, the rudiment has farther down accomplished and finalized its complete eversion, encapsulating the digestive tract and reaching the right side of the larval body. During this process, the genital plates and the associated pedicellariae and immature spines present on the right side of the larva have further completed the production of the aboral part of the adult body. At the end of metamorphosis, hence at the end of the metamorphic larva stage, the individual has thus become benthic, it is settled in the substrate, and it looks like an adult pentaradial sea urchin although it is smaller in size, deprived of a functional digestive system and sexually immature." [] synonym: " meta" EXACT [] synonym: "metamorphosis" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0000480 ! late feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000530 name: adulthood def: "Biological process during which changes occur in biological and psychological domains to generate a sexually mature animal." [] is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by ECAO:0000440 ! larval development relationship: part_of ECAO:0000010 ! life cycle period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000540 name: juvenile period def: "Period during which a young individual, posing as a small adult, grows but remains unable to reproduce." [] xref: UBERON:0034919 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000480 ! late feeding larva period relationship: part_of ECAO:0000530 ! adulthood property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000550 name: early juvenile stage def: "The early juvenile is morphologically similar to both the late rudiment and a miniature sea urchin adult. Like the rudiment, it harbors five primary podia (or tube feet), five quartet of definitive spines, five pairs of immature spines located at the basis of the primary podia, 5 to 7 immature spines supported by the genital plates as well as 1 to 4 pedicellariae. Like the adult, it displays a pentarial symmetry and is settled on the substrate. An early juvenile is about 300 µm in diameter. On its aboral side, it still exhibits some remaining larval rods and tissues, although these will soon disappear. In addition, the plates forming its endoskeleton are still rather light and porous making it looking relatively clear, although it bears lots of red-pigmented cells. However, the postlarva is still deprived of a mouth and an anus, hence of a functional digestive tract. The early juvenile is thus endotrophic, meaning that its growth and development solely relies on energy derived from internal sources. Furthermore, the early juvenile is sexually immature." [] synonym: " endotrophic juvenile" EXACT [] synonym: " postlarva" EXACT [] synonym: "PLJuv" EXACT [] xref: UBERON:0007021 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000520 ! metamorphic larva stage relationship: part_of ECAO:0000540 ! juvenile period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000560 name: late juvenile stage def: "The late juvenile really looks like a small adult. The plates of its endoskeleton have by now densified providing it with a dark shell. In addition, it has finally developed a functional digestive tract. The digestive tract inherited from the larva has indeed by now undergone a complete reorganization, progressively bending within the perivisceral cavity to form two successive loops. The buccal plates and the aristotle lantern have further finished developing, creating a new mouth that has opened on the oral side at the center of the aristotle's lantern, while a new anus has also opened in the periproct, i.e. at the center of the five genital plates. The late juvenile can thus feed and starts growing in size, by grazing on the substrate. The late juvenile is exotrophic, meaning that its growth and development rely on energy derived from external sources. In addition, the primary podia have started to regress by that stage and will eventually disappear, while secondary podia have emerged and are functional, allowing the juvenile to move. Similarly, the immature spines have also started to be lost and be replaced by definitive spines. The genital plate CD has further differentiated into the madreporite and sphaeridia have formed. However, this individual is still sexually immature." [] synonym: "ExJuv" EXACT [] xref: UBERON:0007021 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0000540 ! juvenile period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000570 name: adult period def: "Period during which the animal reaches sexual maturity." [] xref: UBERON:0000066 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000540 ! juvenile period relationship: part_of ECAO:0000530 ! adulthood property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000580 name: adult stage def: "This stage corresponds to a fully formed pentaradial sea urchin that has reached sexual maturity. The gonads have developed within the perivisceral cavity and are connected to the outside by the genital pores pierced into the genital plates. The young adult has grown up to about several centimeters in diameter and is now producing gametes. Time after fertilization is unknown, between several months to one year depending on the sea urchin species and the rate and type of feeding." [] synonym: " gravid sea urchin" EXACT [] synonym: "sexual mature sea urchin" EXACT [] xref: UBERON:0000113 is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0000570 ! adult period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000590 name: very late blastula stage def: "The embryo is composed of about 800 cells and is surrounded by a fertilization envelope. The wall of the embryo is thinner and smoother than at previous stages. The vegetal plate has not formed. Many cells are ciliated but the embryo has not begun to rotate within the fertilization envelope. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 32 large micromere descendants and 4 small micromere descendants at this stage." [] synonym: "vLB" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000310 ! late swimming blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000600 name: vegetal plate stage def: "Stage when the vegetal plate is apparent but primary mesenchyme cells (PMCs) have not started to ingress. Embryos are motile due ciliary beating but have not completed hatching." [] synonym: "VP" EXACT [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000610 name: open mouth stage def: "open mouth stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000620 name: early prism stage def: "early prism stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000630 name: late prism stage def: "late prism stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000640 name: early pluteus stage def: "early pluteus stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000630 ! late prism stage relationship: part_of ECAO:0000450 ! early feeding larva period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000650 name: early organogenesis stage def: "early organogenesis stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000660 name: mid-organogenesis stage def: "mid-organogenesis stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000650 ! early organogenesis stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000670 name: late organogenesis stage def: "late organogenesis stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000660 ! mid-organogenesis stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000680 name: very late organogenesis stage def: "very late organogenesis stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000670 ! late organogenesis stage relationship: part_of ECAO:0000420 ! organogenesis period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0000690 name: mesenchyme blastula stage def: "mesenchyme blastula stage" [] is_a: BFO:0000003 ! occurrent relationship: immediately_preceded_by ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0000240 ! blastula period property_value: oio:hasOBONamespace "ecao_developmental_stage" xsd:string [Term] id: ECAO:0103500 name: echinoderm anatomy def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [] xref: UBERON:0001062 property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103510 name: anatomical structure def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome" [] xref: UBERON:0000061 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103520 name: anatomical system def: "A system that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity. Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function" [] synonym: " body system" EXACT [] synonym: " connected anatomical system" EXACT [] synonym: "organ system" EXACT [] xref: UBERON:0000467 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103530 name: anatomical region def: "A region of the whole organism without well-defined compartmental boundaries" [] synonym: "organism subdivision" EXACT [] xref: UBERON:0000475 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103540 name: anatomical space xref: UBERON:0000464 relationship: part_of ECAO:0103500 ! echinoderm anatomy property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103550 name: whole organism def: "Anatomical structure that is an individual member of a species and consists of one cell or more" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103560 name: multicellular organism def: "Anatomical structure that is an individual member of a species and consists of more than one cell" [] xref: UBERON:0000468 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103570 name: embryo def: "Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems" [] xref: UBERON:0000922 is_a: ECAO:0103560 ! multicellular organism relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103580 name: larva xref: UBERON:0002548 is_a: ECAO:0103560 ! multicellular organism is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103570 ! embryo relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103590 name: juvenile xref: UBERON:0034919 is_a: ECAO:0103560 ! multicellular organism is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103580 ! larva relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103600 name: adult xref: UBERON:0007023 is_a: ECAO:0103560 ! multicellular organism is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103590 ! juvenile relationship: existence_starts_during ECAO:0000580 ! adult stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103610 name: digestive system def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [] xref: UBERON:0001007 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103620 name: embryonic digestive system def: "The gastrointestinal tract that is being formed during embryonic development starting with the formation of the primitive gut tube (or archenteron)" [] is_a: ECAO:0103610 ! digestive system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103630 name: larval digestive system def: "Organ system responsible for the food uptake and processing in the larva" [] is_a: ECAO:0103610 ! digestive system is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103620 ! embryonic digestive system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103640 name: juvenile digestive system is_a: ECAO:0103610 ! digestive system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103650 name: adult digestive system def: "Anatomical system that processes ingested substances in the adult" [] is_a: ECAO:0103610 ! digestive system is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103640 ! juvenile digestive system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103660 name: immune system xref: UBERON:0002405 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103670 name: embryonic immune system is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103680 name: larval immune system is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103690 name: juvenile immune system is_a: ECAO:0103660 ! immune system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103700 name: adult immune system is_a: ECAO:0103660 ! immune system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103710 name: reproductive system def: "Anatomical system that has as its parts the organs concerned with reproduction, i.e. the male and female gonads." [] xref: UBERON:0000990 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103720 name: nervous system xref: UBERON:0001016 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103730 name: embryonic nervous system def: "The sum of all the structures in the embryo that will develop into the larval nervous system" [] is_a: ECAO:0103720 ! nervous system relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103740 name: larval nervous system def: "The sum of all the neural structures present in the larva" [] is_a: ECAO:0103720 ! nervous system is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103730 ! embryonic nervous system relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103750 name: juvenile nervous system is_a: ECAO:0103720 ! nervous system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103760 name: adult nervous system xref: UBERON:6003559 is_a: ECAO:0103720 ! nervous system is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103750 ! juvenile nervous system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103770 name: muscular system xref: UBERON:0000383 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103780 name: larval muscular system is_a: ECAO:0103770 ! muscular system relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103790 name: juvenile muscular system is_a: ECAO:0103770 ! muscular system relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103800 name: adult muscular system xref: UBERON:6003218 is_a: ECAO:0103770 ! muscular system is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103790 ! juvenile muscular system relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103810 name: endoskeleton def: "Internal support structure of an animal composed of mineralized tissue. It gives shape, support and protection to the body." [] xref: UBERON:0001434 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103820 name: embryonic endoskeleton is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103830 name: larval endoskeleton is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103840 name: rudiment endoskeleton synonym: "skeletal rudiment" EXACT [] is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103850 name: juvenile endoskeleton is_a: ECAO:0103810 ! endoskeleton relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103860 name: adult endoskeleton is_a: ECAO:0103810 ! endoskeleton relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103870 name: water vascular system def: "The water vascular system is a hydraulic system used by sea urchins for locomotion, food and waste transportation, and respiration. The system is composed of canals connecting numerous tube feet." [] xref: UBERON:0008251 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103880 name: hemal system def: "The hemal system contains the blood. It is composed of a complex network of vessels mainly located around the gut." [] synonym: "haemal system" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103520 ! anatomical system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103890 name: animal hemisphere def: "Anatomical region that corresponds to the upper half of the embryo, which later is composed of the mesomeres, and ultimately encompasses the presumptive ectoderm" [] synonym: " upper half" EXACT [] synonym: " upper hemisphere" EXACT [] synonym: "animal half" EXACT [] xref: UBERON:0012284 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103900 name: vegetal hemisphere def: "Anatomical region that corresponds to the lower half of the embryo, which later is composed of the macromeres and the micromeres, and ultimately encompasses the endoderm and mesoderm" [] synonym: " lower half" EXACT [] synonym: " lower hemisphere" EXACT [] synonym: "vegetal half" EXACT [] xref: UBERON:0012285 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103910 name: cell cortex is_a: ECAO:0104040 ! cell part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103920 name: cleavage furrow is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103930 name: animal cortex def: "Cell component comprising the outermost layer of the animal region of the oocyte. It consists of a phospholipid bilayer and associated proteins" [] is_a: ECAO:0103910 ! cell cortex relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103940 name: vegetal cortex def: "Cell component comprising the outermost layer of the vegetal region of the oocyte. It consists of a phospholipid bilayer and associated proteins" [] is_a: ECAO:0103910 ! cell cortex relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103950 name: animal pole def: "The apical region of the animal hemisphere" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103960 name: vegetal pole def: "The apical most region of the vegetal hemisphere. Once cleavages have started the vegetal pole is characterized by the presence of the micromeres initially and then that of the small micromeres" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103970 name: animal pole domain synonym: " animal plate" EXACT [] synonym: " anterior neuroectoderm" EXACT [] synonym: " apical plate" EXACT [] synonym: " neurogenic ectoderm" EXACT [] synonym: "apical pole domain" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103980 name: blastopore xref: UBERON:0000100 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103620 ! embryonic digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0103990 name: blastopore lip xref: UBERON:3010455 is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103980 ! blastopore property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104000 name: bottle cell is_a: ECAO:0104010 ! embryonic cell relationship: existence_ends_during ECAO:0000380 ! blastopore formation stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0104020 ! vegetal plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104010 name: embryonic cell is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000160 ! 2-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104020 name: vegetal plate is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000360 ! late mesenchyme blastula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104030 name: cell def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104040 name: cell part def: "Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher." [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000040 ! previtellogenic primary oocyte stage relationship: part_of ECAO:0104030 ! cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104050 name: digestive system element def: "Any of the organs or elements that are part of the digestive system" [] xref: UBERON:0013765 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104060 name: skeletal element xref: UBERON:0004765 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0103810 ! endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104070 name: embryonic structure def: "Any anatomical structure that is part of an embryo" [] xref: UBERON:0002050 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104080 name: larval structure def: "Any anatomical structure that is part of a larva" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104090 name: juvenile structure def: "Any anatomical structure that is part of a juvenile" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104100 name: adult structure def: "Any anatomical structure that is part of an adult" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104110 name: tissue xref: UBERON:0000479 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0103560 ! multicellular organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104120 name: rudiment synonym: " imaginal adult rudiment" EXACT [] synonym: "adult rudiment" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104130 name: rudiment structure is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104140 name: non-rudiment adult structure is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104147 name: intracellular part is_a: ECAO:0104040 ! cell part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104148 name: cytoskeleton is_a: ECAO:0104147 ! intracellular part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104150 name: microtubule is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104160 name: nucleus def: "A membrane-bounded organelle of in which chromosomes are housed and replicated. In most cells, it contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some specialized cell types, RNA metabolism or DNA replication may be absent" [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104168 name: oocyte def: "A female haploid germ cell." [] is_a: ECAO:0104580 ! gamete relationship: existence_ends_during ECAO:0000030 ! oogenesis period relationship: existence_starts_during ECAO:0000030 ! oogenesis period property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104170 name: germinal vesicle def: "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity" [] is_a: ECAO:0104160 ! nucleus relationship: existence_ends_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: existence_starts_during ECAO:0000050 ! not fully grown oocyte stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104180 name: equatorial pigment band def: "The subequatorial accumulation of pigment granules (the so-called ‘pigment band’) in eggs or early stage embryos, which constitutes an unambiguous marker of animal-vegetal polarity" [] synonym: " pigmented band" EXACT [] synonym: "pigment band" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000060 ! fully grown oocyte with centered germinal vesicle stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104190 name: cytoplasm def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures" [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000050 ! not fully grown oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104200 name: centrosome is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104210 name: mitotic spindle is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000140 ! 1-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104220 name: meiotic spindle is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104230 name: fertilization envelope def: "A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release" [] synonym: "fertilization membrane" EXACT [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_ends_during ECAO:0000280 ! late blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104247 name: spermatozoid def: "A mature male germ cell" [] synonym: " male gamete" EXACT [] synonym: " mature sperm cell" EXACT [] synonym: " spermatozoa" EXACT [] synonym: " spermatozoan" EXACT [] synonym: "sperm" EXACT [] is_a: ECAO:0104580 ! gamete relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104248 name: aster synonym: " mitotic aster" EXACT [] synonym: "spindle aster" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104250 name: sperm aster synonym: "spermatozoid aster" EXACT [] is_a: ECAO:0104248 ! aster relationship: existence_ends_during ECAO:0000120 ! mature spermatozoid stage relationship: existence_starts_during ECAO:0000120 ! mature spermatozoid stage relationship: part_of ECAO:0104247 ! spermatozoid property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104270 name: acellular membrane xref: UBERON:0005764 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000090 ! mature oocyte stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104280 name: vitelline membrane synonym: " vitelline envelope" EXACT [] synonym: "vitelline layer" EXACT [] xref: UBERON:0003125 is_a: ECAO:0104270 ! acellular membrane relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104300 name: hyaline layer synonym: "hyaline membrane" EXACT [] is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104310 name: microvillus is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104320 name: apical lamina synonym: "fibropellin layer" EXACT [] is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0104300 ! hyaline layer property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104330 name: secretory vesicle is_a: ECAO:0104147 ! intracellular part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104340 name: cilium is_a: ECAO:0104040 ! cell part relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104350 name: filopodium is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104360 name: basal lamina xref: UBERON:0000482 is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104370 name: basal laminar vesicle synonym: " basal vesicle" EXACT [] synonym: "basal lamina vesicle" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104380 name: apical vesicle is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104390 name: cortical granule synonym: "cortical vesicle" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104400 name: echinonectin vesicle synonym: " echinonectin granule" EXACT [] synonym: "nectosome" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104410 name: mitochondrion is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104420 name: actin cytoskeleton is_a: ECAO:0104148 ! cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104430 name: actin filament synonym: " F-actin filament" EXACT [] synonym: "microfilament" EXACT [] is_a: ECAO:0104147 ! intracellular part relationship: part_of ECAO:0104420 ! actin cytoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104440 name: nuclear part is_a: ECAO:0104147 ! intracellular part relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0104160 ! nucleus property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104450 name: nucleoplasm is_a: ECAO:0104440 ! nuclear part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104460 name: nuclear envelope is_a: ECAO:0104440 ! nuclear part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104470 name: endoplasmic reticulum is_a: ECAO:0104147 ! intracellular part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104480 name: spermatozoid entry point is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000140 ! 1-cell stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104490 name: plasma membrane synonym: "cell membrane" EXACT [] is_a: ECAO:0104040 ! cell part relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104500 name: polar body def: "A small cell formed by the meiotic division of an oocyte" [] is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: existence_starts_during ECAO:0000070 ! fully grown oocyte with off-centered germinal vesicle stage relationship: part_of ECAO:0104168 ! oocyte property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104510 name: spermatozoid part synonym: "sperm part" EXACT [] is_a: ECAO:0104040 ! cell part relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period relationship: part_of ECAO:0104247 ! spermatozoid property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104520 name: spermatozoid head def: "The part of the late spermatid or spermatozoon that contains the nucleus and acrosome." [] is_a: ECAO:0104510 ! spermatozoid part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104530 name: spermatozoid flagellum def: "A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid" [] synonym: "sperm tail" EXACT [] is_a: ECAO:0104510 ! spermatozoid part property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104540 name: acrosomal vesicle def: "An organelle that develops over the anterior half of the head in the spermatozoa" [] synonym: "acrosome" EXACT [] is_a: ECAO:0104330 ! secretory vesicle relationship: existence_ends_during ECAO:0000100 ! spermatogenesis period relationship: existence_starts_during ECAO:0000100 ! spermatogenesis period relationship: part_of ECAO:0104520 ! spermatozoid head property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104548 name: small micromere descendant cell synonym: "presumptive primordial germ cell" EXACT [] is_a: ECAO:0104630 ! blastomere is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104720 ! small micromere relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104550 name: presumptive primordial germ cell is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104548 ! small micromere descendant cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104560 name: primordial germ cell is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104570 name: germ cell is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104560 ! primordial germ cell relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104580 name: gamete is_a: ECAO:0104570 ! germ cell relationship: existence_ends_during ECAO:0000020 ! gametogenesis relationship: existence_starts_during ECAO:0000020 ! gametogenesis property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104600 name: immature occyte synonym: "immature egg" EXACT [] is_a: ECAO:0104168 ! oocyte relationship: existence_ends_during ECAO:0000080 ! fully grown oocyte with no nucleus stage relationship: part_of ECAO:0104560 ! primordial germ cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104610 name: mature oocyte def: "A mature female gamet that has entered meiosis." [] synonym: " female gamete" EXACT [] synonym: " female germ cell" EXACT [] synonym: " unfertilized egg" EXACT [] synonym: "egg" EXACT [] is_a: ECAO:0104168 ! oocyte relationship: develops_from ECAO:0104600 ! immature occyte relationship: existence_ends_during ECAO:0000090 ! mature oocyte stage relationship: existence_starts_during ECAO:0000090 ! mature oocyte stage relationship: part_of ECAO:0104570 ! germ cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104630 name: blastomere def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)" [] synonym: "blastoderm cell" EXACT [] is_a: ECAO:0104010 ! embryonic cell relationship: existence_ends_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104640 name: blastomere of 2-cell embryo is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000160 ! 2-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104650 name: blastomere of 4-cell embryo is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000170 ! 4-cell stage relationship: existence_starts_during ECAO:0000170 ! 4-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104660 name: mesomere def: "Intermediate size blastomere forming the animal hemisphere of the cleaving embryo" [] synonym: "mesomeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000190 ! 16-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104670 name: macromere def: "Larger blastomere of the vegetal hemisphere of the cleaving embryo located below the equator" [] synonym: "macromeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000190 ! 16-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104678 name: cell tier synonym: "blastomere tier" EXACT [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_ends_during ECAO:0000280 ! late blastula stage relationship: existence_starts_during ECAO:0000180 ! 8-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104680 name: macromere daughter cell tier is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000210 ! 32-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104690 name: micromere def: "Small blastomere of the vegetal hemisphere of the cleaving embryo located at to the vegetal pole" [] synonym: "micromeres" EXACT [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000200 ! 28-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104700 name: large micromere is_a: ECAO:0104630 ! blastomere is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104690 ! micromere relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104710 name: large micromere descendant cell synonym: " presumptive PMC" EXACT [] synonym: " presumptive primary mesenchyme cell" EXACT [] synonym: " presumptive skeletogenic mesenchyme cell" EXACT [] synonym: "large micromere progeny" EXACT [] is_a: ECAO:0104630 ! blastomere is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000340 ! early mesenchyme blastula stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104720 name: small micromere synonym: "SM" EXACT [] is_a: ECAO:0104630 ! blastomere is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104690 ! micromere relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104740 name: presumptive neuron def: "A progenitor cell of the nervous system that will develop into a neuron" [] synonym: "neuronal progenitor cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104750 name: animal pole domain presumptive neuron synonym: " animal pole domain neuronal progenitor cell" EXACT [] synonym: "apical pole domain presumptive neuron" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104760 name: ectoderm presumptive neuron synonym: "ectoderm neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104770 name: ciliary band presumptive neuron synonym: "ciliary band neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104780 name: endoderm associated presumptive neuron synonym: "endoderm associated neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104790 name: neuron synonym: "nerve cell" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104740 ! presumptive neuron relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104800 name: larval neuron is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103740 ! larval nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104810 name: serotonergic neuron is_a: ECAO:0104790 ! neuron relationship: develops_from ECAO:0104750 ! animal pole domain presumptive neuron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104820 name: synaptotagmin-B neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104830 name: dopaminergic neuron is_a: ECAO:0104790 ! neuron relationship: develops_from ECAO:0104760 ! ectoderm presumptive neuron relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104840 name: GABAergic neuron is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104850 name: sensory neuron synonym: "sensory cell" EXACT [] is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104860 name: biopolar neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104870 name: multipolar neuron is_a: ECAO:0104790 ! neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104878 name: neural structure synonym: "neuronal structure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103720 ! nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104880 name: axon tract synonym: " axon bundle" EXACT [] synonym: "axonal tract" EXACT [] xref: UBERON:0001018 is_a: ECAO:0104878 ! neural structure property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104900 name: ciliary band neuron synonym: "peripheral neuron" EXACT [] is_a: ECAO:0104800 ! larval neuron relationship: develops_from ECAO:0104770 ! ciliary band presumptive neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104908 name: ectoderm def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [] xref: UBERON:0000924 is_a: ECAO:0105150 ! germ layer relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104910 name: presumptive ciliary band cell is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104908 ! ectoderm relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104920 name: endoderm associated neuron is_a: ECAO:0104800 ! larval neuron relationship: develops_from ECAO:0104780 ! endoderm associated presumptive neuron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104930 name: ganglion xref: UBERON:0000045 is_a: ECAO:0104878 ! neural structure property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104940 name: apical ganglion synonym: "apical organ" EXACT [] is_a: ECAO:0104930 ! ganglion is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103970 ! animal pole domain relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103740 ! larval nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104950 name: adult neuron is_a: ECAO:0104790 ! neuron relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104960 name: circumoral nerve ring is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104970 name: enteric nerve plexus synonym: " digestive nerve plexus" EXACT [] synonym: "enteric plexus" EXACT [] xref: UBERON:0000429 is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104980 name: radial nerve cord is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0104990 name: primary podia associated neuron is_a: ECAO:0104950 ! adult neuron relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105000 name: secondary podia associated neuron is_a: ECAO:0104950 ! adult neuron relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105010 name: definitive spine associated neuron is_a: ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105020 name: pedicellaria associated neuron is_a: ECAO:0104950 ! adult neuron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105030 name: basiepidermal nerve plexus is_a: ECAO:0104878 ! neural structure relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103760 ! adult nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105050 name: animal quartet def: "Group of four cells of equal size forming the animal hemisphere of an eight-cell stage embryo" [] is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105060 name: vegetal quartet def: "Group of four cells of equal size forming the vegetal hemisphere of an eight-cell stage embryo" [] is_a: ECAO:0104678 ! cell tier relationship: existence_ends_during ECAO:0000180 ! 8-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105070 name: animal tier 1 synonym: "an1" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000230 ! 60-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105080 name: animal tier 2 synonym: "an2" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000230 ! 60-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105090 name: vegetal tier 1 synonym: " ectoendoderm" EXACT [] synonym: "veg1" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104670 ! macromere relationship: existence_ends_during ECAO:0000260 ! early blastula stage relationship: existence_starts_during ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105100 name: vegetal tier 2 synonym: " endomesoderm" EXACT [] synonym: "veg2" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104670 ! macromere relationship: existence_ends_during ECAO:0000260 ! early blastula stage relationship: existence_starts_during ECAO:0000220 ! 56-cell stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105110 name: vegetal tier 1 upper synonym: " presumptive vegetal ectoderm" EXACT [] synonym: " veg1 upper" EXACT [] synonym: "veg1U" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105120 name: vegetal tier 1 lower synonym: " veg1 lower" EXACT [] synonym: "veg1L" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105130 name: vegetal tier 2 upper synonym: " veg2 upper" EXACT [] synonym: "veg2U" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105140 name: vegetal tier 2 lower synonym: " presumptive non-skeletogenic mesoderm" EXACT [] synonym: " veg2 lower" EXACT [] synonym: "veg2L" EXACT [] is_a: ECAO:0104678 ! cell tier is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105150 name: germ layer synonym: " embryonic germ layer" EXACT [] synonym: "primary germ layer" EXACT [] xref: UBERON:0000923 is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105158 name: embryonic tissue xref: UBERON:0005291 is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105160 name: presumptive ectoderm xref: UBERON:0006601 is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104660 ! mesomere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103890 ! animal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105180 name: animal ectoderm is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105190 name: vegetal ectoderm is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105200 name: ventral ectoderm synonym: "oral ectoderm" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105210 name: dorsal ectoderm synonym: "aboral ectoderm" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105220 name: ectoendoderm synonym: " veg1" EXACT [] synonym: "vegetal tier 1" EXACT [] is_a: ECAO:0105150 ! germ layer is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105090 ! vegetal tier 1 relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105230 name: endomesoderm synonym: " mesoendoderm" EXACT [] synonym: " veg2" EXACT [] synonym: "vegetal tier 2" EXACT [] is_a: ECAO:0105150 ! germ layer is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105240 name: inner animal pole domain synonym: "inner apical pole domain" EXACT [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105250 name: outer animal pole domain synonym: "outer apical pole domain" EXACT [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105260 name: central ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105270 name: border ectoderm synonym: "BE" EXACT [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105220 ! ectoendoderm relationship: existence_ends_during ECAO:0000330 ! mesenchyme blastula phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105280 name: near-apical ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105290 name: apical ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000240 ! blastula period relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105300 name: veg1-lateral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105310 name: veg-1 oral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105320 name: lateral ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000370 ! invagination phase relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105330 name: right lateral ectoderm is_a: ECAO:0105320 ! lateral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105340 name: left lateral ectoderm is_a: ECAO:0105320 ! lateral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105350 name: arm tip ectoderm is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105360 name: dorsal arm tip ectoderm is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0105350 ! arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105370 name: ventral arm tip ectoderm is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0105350 ! arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105380 name: apical tuft is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_starts_during ECAO:0000590 ! very late blastula stage relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105400 name: larval tissue is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105410 name: rudiment tissue is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105420 name: juvenile tissue is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103590 ! juvenile property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105430 name: adult tissue is_a: ECAO:0104110 ! tissue relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105440 name: presumptive stomodeum is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105450 name: stomodeum synonym: "presumptive mouth" EXACT [] xref: UBERON:0000930 is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105440 ! presumptive stomodeum relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105460 name: ciliary band is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0104908 ! ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105470 name: oral hood ciliary band is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105480 name: arm ciliary band is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105490 name: animal pole ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105500 name: vegetal ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105510 name: lateral ciliary band is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0105460 ! ciliary band property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105520 name: oral hood synonym: " PL" EXACT [] synonym: " preoral lobe" EXACT [] synonym: "oh" EXACT [] is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105530 name: apex is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105540 name: larval arm is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105550 name: right anterolateral arm synonym: " ALA" EXACT [] synonym: "AL" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105560 name: left anterolateral arm synonym: " ALA" EXACT [] synonym: "AL" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105570 name: right postoral arm synonym: "PO" EXACT [] is_a: ECAO:0105540 ! larval arm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105580 name: left postoral arm synonym: "PO" EXACT [] is_a: ECAO:0105540 ! larval arm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105590 name: right posterodorsal arm synonym: "PD" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105600 name: left posterodorsal arm synonym: "PD" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105610 name: right preoral arm synonym: " PRO" EXACT [] synonym: "PR" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105620 name: left preoral arm synonym: " PRO" EXACT [] synonym: "PR" EXACT [] is_a: ECAO:0105540 ! larval arm relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105628 name: spicule rudiment is_a: ECAO:0104060 ! skeletal element property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105630 name: spicule granule synonym: "spicule dot" EXACT [] is_a: ECAO:0105628 ! spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105650 name: triradiate spicule rudiment synonym: "spicule primordium" EXACT [] is_a: ECAO:0105628 ! spicule rudiment is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105630 ! spicule granule property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105660 name: right ventrolateral triradiate spicule rudiment synonym: "triradiate spicule" EXACT [] is_a: ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105670 name: left ventrolateral triradiate spicule rudiment is_a: ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105680 name: hexaradiate spicule rudiment synonym: "hexaradiate spicule" EXACT [] is_a: ECAO:0105628 ! spicule rudiment is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105630 ! spicule granule relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105690 name: larval spicule def: "A triradiate or hexaradiate minute calcareous skeletal element that initiates most if not all skeletal structures found within the sea urchin embryo, larva and adult." [] synonym: "primary triradiate skeletal rudiment" EXACT [] is_a: ECAO:0104060 ! skeletal element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105698 name: embryonic skeletogenic mesenchyme def: "The embryonic tissue made up of loosely connected mesoderm cells that will produce all of the skeletal elements." [] synonym: " primary mesenchyme" EXACT [] synonym: "SM" EXACT [] is_a: ECAO:0104110 ! tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106220 ! embryonic skeletogenic mesoderm relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105700 name: skeletal rod synonym: "spicule rod" EXACT [] is_a: ECAO:0104060 ! skeletal element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000550 ! early juvenile stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105710 name: anonymous rod is_a: ECAO:0105700 ! skeletal rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105720 name: right anonymous rod is_a: ECAO:0105710 ! anonymous rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105730 name: left anonymous rod is_a: ECAO:0105710 ! anonymous rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105738 name: right dorsoventral connecting rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105740 name: right anterolateral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105738 ! right dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105748 name: left dorsoventral connecting rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105750 name: left anterolateral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105748 ! left dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105760 name: right postoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105720 ! right anonymous rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105770 name: left postoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105730 ! left anonymous rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105780 name: right posterodorsal rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105790 name: left posterodorsal rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105798 name: dorsal arch is_a: ECAO:0104060 ! skeletal element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105800 name: right preoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105798 ! dorsal arch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105810 name: left preoral rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105798 ! dorsal arch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105850 name: right ventral transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105660 ! right ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105860 name: left ventral transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105670 ! left ventrolateral triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105868 name: posterior tip of body rod is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0105880 ! body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105870 name: scheitel synonym: "body rod end" EXACT [] is_a: ECAO:0104060 ! skeletal element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105868 ! posterior tip of body rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105880 name: body rod is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105890 name: left body rod is_a: ECAO:0105880 ! body rod is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105730 ! left anonymous rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105900 name: right body rod is_a: ECAO:0105880 ! body rod is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105720 ! right anonymous rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105920 name: posterior tip of left body rod is_a: ECAO:0105868 ! posterior tip of body rod relationship: part_of ECAO:0105890 ! left body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105930 name: posteror tip of right body rod is_a: ECAO:0105868 ! posterior tip of body rod relationship: part_of ECAO:0105900 ! right body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105940 name: right recurrent rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105738 ! right dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105950 name: left recurrent rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105748 ! left dorsoventral connecting rod relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105960 name: posterior transverse rod is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105650 ! triradiate spicule rudiment relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103830 ! larval endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105970 name: mouth xref: UBERON:0000165 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105980 name: larval mouth is_a: ECAO:0105970 ! mouth is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105450 ! stomodeum relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0105990 name: anus xref: UBERON:0001245 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106000 name: larval anus is_a: ECAO:0105990 ! anus is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103980 ! blastopore relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106010 name: presumptive endoderm synonym: "prospective endoderm" EXACT [] xref: UBERON:0006595 is_a: ECAO:0105158 ! embryonic tissue relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000260 ! early blastula stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106020 name: endoderm xref: UBERON:0000925 is_a: ECAO:0105150 ! germ layer is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106010 ! presumptive endoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000270 ! mid-blastula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106030 name: archenteron synonym: " primitive gut" EXACT [] synonym: "embryonic gut" EXACT [] xref: UBERON:0004735 is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000380 ! blastopore formation stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106040 name: hindgut xref: UBERON:0001046 is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106050 name: dorsal hindgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106060 name: ventral hindgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106070 name: midgut xref: UBERON:0001045 is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106080 name: ventral midgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106090 name: dorsal midgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106100 name: anterior midgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106110 name: posterior midgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106070 ! midgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106120 name: anterior hindgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106130 name: posterior hindgut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106040 ! hindgut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106140 name: foregut synonym: "tip of the digestive tract" EXACT [] xref: UBERON:0001041 is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106150 name: ventral foregut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106160 name: dorsal foregut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106170 name: anterior foregut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106180 name: posterior foregut is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106140 ! foregut property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106190 name: tip of archenteron synonym: "archenteron roof" EXACT [] xref: UBERON:3010432 is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0106030 ! archenteron property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106200 name: presumptive mesoderm synonym: "prospective mesoderm" EXACT [] xref: UBERON:0006603 is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103900 ! vegetal hemisphere property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106210 name: mesoderm xref: UBERON:0000926 is_a: ECAO:0105150 ! germ layer is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106200 ! presumptive mesoderm relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106220 name: embryonic skeletogenic mesoderm def: "The subset of the embryonic mesoderm that will later give rise to the skeletogenic mesenchyme and embryonic skeleton." [] is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000590 ! very late blastula stage relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0106210 ! mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106240 name: embryonic skeletogenic mesenchyme cell synonym: " primary mesenchyme cell" EXACT [] synonym: "PMC" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104700 ! large micromere relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000340 ! early mesenchyme blastula stage relationship: part_of ECAO:0105698 ! embryonic skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106250 name: syncytium synonym: " multinucleated cell" EXACT [] synonym: " syncytial cell" EXACT [] synonym: " syncytium" EXACT [] synonym: "multinucleate cell" EXACT [] is_a: ECAO:0104030 ! cell property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106260 name: embryonic skeletogenic mesenchyme syncytium def: "Anatomical structure composed of skeletogenic mesenchyme cells that have fused to form a single syncytial network." [] is_a: ECAO:0106250 ! syncytium is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103810 ! endoskeleton property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106270 name: subequatorial skeletogenic mesenchyme ring synonym: " PMC ring" EXACT [] synonym: " primary mesenchyme cell ring" EXACT [] synonym: " subequatorial PMC ring" EXACT [] synonym: " subequatorial primary mesenchyme cell ring" EXACT [] synonym: " subequatorial SM ring" EXACT [] synonym: "SM ring" EXACT [] is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106260 ! embryonic skeletogenic mesenchyme syncytium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106280 name: ventral skeletogenic mesenchyme chain def: "Subpopulation of skeletogenic mesenchyme forming a chain on the oral (i.e. ventral) side of the embryo." [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106290 name: dorsal skeletogenic mesenchyme chain def: "Subpopulation of skeletogenic mesenchyme forming a chain on the aboral (i.e. dorsal) side of the embryo." [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106300 name: right ventrolateral skeletogenic mesenchyme cluster def: "Subpopulation of skeletogenic mesenchyme forming a cluster (i.e. a group of cells) in the ventrolateral region of the embryo." [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106310 name: left ventrolateral skeletogenic mesenchyme cluster is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106320 name: lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain on either side of the developing digestive tract, along the blastocoel wall and towards the animal pole." [] is_a: ECAO:0104070 ! embryonic structure relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106260 ! embryonic skeletogenic mesenchyme syncytium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106330 name: right lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the right side of the embryo." [] is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106320 ! lateral chain of skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106340 name: left lateral chain of skeletogenic mesenchyme def: "Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the left side of the embryo." [] is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0106320 ! lateral chain of skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106350 name: embryonic non-skeletogenic mesoderm is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000590 ! very late blastula stage relationship: part_of ECAO:0106210 ! mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106360 name: ventral non-skeletogenic mesoderm is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106370 name: dorsal non-skeletogenic mesoderm is_a: ECAO:0105158 ! embryonic tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106380 name: embryonic non-skeletogenic mesenchyme synonym: " NSM" EXACT [] synonym: "secondary mesenchyme" EXACT [] is_a: ECAO:0104110 ! tissue is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106390 name: embryonic non-skeletogenic mesenchyme cell synonym: " secondary mesenchyme cell" EXACT [] synonym: "SMC" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0106380 ! embryonic non-skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106400 name: larval non-skeletogenic mesenchyme is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106410 name: larval non-skeletogenic mesenchyme cell is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106400 ! larval non-skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106420 name: presumptive blastocoelar cell is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105100 ! vegetal tier 2 relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106430 name: presumptive pigment cell synonym: " presumptive immunocyte" EXACT [] synonym: "presumptive pigmented cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000330 ! mesenchyme blastula phase relationship: part_of ECAO:0106350 ! embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106440 name: pigment cell def: "a cell that contains red coloring matter" [] synonym: " pigmented immunocyte" EXACT [] synonym: "pigmented cell" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106430 ! presumptive pigment cell relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000390 ! early gastrula stage relationship: part_of ECAO:0103660 ! immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106450 name: embryonic pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103670 ! embryonic immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106460 name: larval pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106470 name: juvenile pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103690 ! juvenile immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106480 name: rudiment pigment cell is_a: ECAO:0106440 ! pigment cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0104120 ! rudiment property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106490 name: blastocoelar cell is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106420 ! presumptive blastocoelar cell relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103660 ! immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106500 name: globular cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106510 name: filopodial cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106520 name: ovoid cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106530 name: amoeboid cell is_a: ECAO:0106490 ! blastocoelar cell relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103680 ! larval immune system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106540 name: muscle precursor cell synonym: "presumptive muscle cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000460 ! early pluteus larva stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106550 name: muscle is_a: ECAO:0104110 ! tissue relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106560 name: larval muscle synonym: "contractile muscle" EXACT [] is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0103780 ! larval muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106570 name: rudiment muscle is_a: ECAO:0105410 ! rudiment tissue relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106580 name: juvenile muscle is_a: ECAO:0105420 ! juvenile tissue relationship: part_of ECAO:0103790 ! juvenile muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106590 name: adult muscle is_a: ECAO:0105430 ! adult tissue relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103800 ! adult muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106600 name: blastocoel xref: UBERON:0000090 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103540 ! anatomical space relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: existence_starts_during ECAO:0000250 ! very early blastula stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106610 name: sphincter is_a: ECAO:0104050 ! digestive system element relationship: existence_starts_during ECAO:0000430 ! prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106620 name: pyloric sphincter synonym: "midgut-hindgut constriction" EXACT [] is_a: ECAO:0106610 ! sphincter is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106630 name: cardiac sphincter synonym: "foregut-midgut constriction" EXACT [] is_a: ECAO:0106610 ! sphincter is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106640 name: anal sphincter synonym: "hindgut-ectoderm constriction" EXACT [] is_a: ECAO:0106610 ! sphincter is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106650 name: sphincter muscle xref: UBERON:0004590 is_a: ECAO:0106550 ! muscle is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106660 name: sphincter muscle cell synonym: "myoepithelial cell" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106030 ! archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106650 ! sphincter muscle property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106670 name: pyloric sphincteric muscle synonym: "pyloric sphincter" EXACT [] xref: UBERON:0001202 is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106620 ! pyloric sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106680 name: cardiac sphincteric muscle synonym: "cardiac sphincter" EXACT [] is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106630 ! cardiac sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106690 name: anal sphincteric muscle synonym: "anal sphincter" EXACT [] xref: UBERON:0004916 is_a: ECAO:0106650 ! sphincter muscle relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0106640 ! anal sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106700 name: larval esophagus is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106140 ! foregut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106708 name: circumesophageal muscle is_a: ECAO:0106560 ! larval muscle is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106700 ! larval esophagus property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106710 name: circumesophageal muscle cell synonym: "presumptive circumesophageal muscle cell" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0106708 ! circumesophageal muscle property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106730 name: larval stomach is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106070 ! midgut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106740 name: larval intestine is_a: ECAO:0104050 ! digestive system element is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106040 ! hindgut relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103630 ! larval digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106750 name: larval skeletogenic mesenchyme def: "The mesenchyme cells that produce new skeletal elements (i.e., the posterodorsal rods, dorsal arch, and preoral rods) in the larva after feeding begins" [] is_a: ECAO:0104110 ! tissue relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106760 name: larval skeletogenic mesenchyme cell is_a: ECAO:0104030 ! cell relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106750 ! larval skeletogenic mesenchyme property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106770 name: coelom xref: UBERON:0011997 is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106190 ! tip of archenteron relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106780 name: unpaired coelomic pouch synonym: "unpaired coelomic rudiment" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000430 ! prism stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106790 name: right coelomic pouch is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106800 name: left coelomic pouch synonym: "left coelomic sac" EXACT [] is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106810 name: right coelomic constriction is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106790 ! right coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106820 name: left coelomic constriction is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106780 ! unpaired coelomic pouch relationship: existence_ends_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: existence_starts_during ECAO:0000460 ! early pluteus larva stage relationship: part_of ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106828 name: larval epithelium is_a: ECAO:0105400 ! larval tissue relationship: existence_ends_during ECAO:0000520 ! metamorphic larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106830 name: vestibule synonym: "amniotic sac" EXACT [] is_a: ECAO:0104080 ! larval structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105200 ! ventral ectoderm relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106840 name: oral epithelium synonym: " circumoral ectoderm" EXACT [] synonym: " circumoral epithelium" EXACT [] synonym: "oral epidermis" EXACT [] xref: UBERON:0002424 is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106850 name: aboral epithelium is_a: ECAO:0105400 ! larval tissue relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106858 name: left lateral field def: "The left lateral field is the lateral field located on the left side of the larva" [] is_a: ECAO:0107100 ! lateral field property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106860 name: vestibular pore def: "Opening located in the left lateral field" [] is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106858 ! left lateral field relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000510 ! competent pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106868 name: axocoel synonym: "anterior coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106870 name: left axocoel is_a: ECAO:0106868 ! axocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106880 name: axial coelom is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106870 ! left axocoel relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106890 name: hydrocoel synonym: "central coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106910 name: somatocoel synonym: "posterior coelom" EXACT [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106920 name: left hydrocoel is_a: ECAO:0106890 ! hydrocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106930 name: left somatocoel is_a: ECAO:0106910 ! somatocoel relationship: develops_from ECAO:0106800 ! left coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106940 name: right axohydrocoel synonym: "anterior sac" EXACT [] is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106790 ! right coelomic pouch relationship: existence_ends_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106950 name: right somatocoel is_a: ECAO:0106910 ! somatocoel relationship: develops_from ECAO:0106790 ! right coelomic pouch property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106958 name: axial complex is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106960 name: stone canal is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106800 ! left coelomic pouch relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106970 name: ring canal is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106920 ! left hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106980 name: radial canal is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106920 ! left hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0106990 name: primary pore canal synonym: "hydropore canal" EXACT [] is_a: ECAO:0104080 ! larval structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106380 ! embryonic non-skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107000 name: hydropore is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000470 ! 4-arm pluteus larva stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107010 name: right axocoel is_a: ECAO:0106868 ! axocoel relationship: develops_from ECAO:0106940 ! right axohydrocoel property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107020 name: right hydrocoel is_a: ECAO:0106890 ! hydrocoel relationship: develops_from ECAO:0106940 ! right axohydrocoel property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107040 name: axial sinus is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0107020 ! right hydrocoel relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107050 name: axial organ is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107060 name: dorsal sac is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0106958 ! axial complex property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107070 name: ciliated epaulette is_a: ECAO:0104080 ! larval structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105460 ! ciliary band relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000490 ! 6-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107080 name: anterior ciliated epaulette is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107070 ! ciliated epaulette property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107090 name: posterior ciliated epaulette is_a: ECAO:0104080 ! larval structure relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107070 ! ciliated epaulette property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107100 name: lateral field def: "The lateral field is located in the aboral ectoderm of the larva. It separates the anterior and posterior pairs of epaulettes" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000510 ! competent pluteus larva stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0106828 ! larval epithelium property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107120 name: right lateral field def: "The right lateral field is the lateral field located on the right side of the larva" [] is_a: ECAO:0107100 ! lateral field property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107140 name: ambulacral plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107150 name: adult skeletogenic mesenchyme def: "The mesenchyme cells that produce biomineralized elements (e.g., spines, test plates, and teeth) in the juvenile and adult." [] is_a: ECAO:0104110 ! tissue relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103600 ! adult property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107160 name: interambulacral plate synonym: "int" EXACT [] is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107170 name: ambulacra is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107180 name: interambulacra is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107190 name: genital plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107200 name: appendage is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107210 name: pedicellaria xref: UBERON:0008261 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107220 name: ocular plate synonym: "terminal plate" EXACT [] is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107230 name: buccal plate is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107240 name: genital plate AB is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107250 name: genital plate BC is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107260 name: genital plate CD is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107270 name: genital plate DE is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107280 name: genital plate EA is_a: ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107290 name: podia synonym: "tube foot" EXACT [] xref: UBERON:0008247 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107300 name: primary podia synonym: "primary tube foot" EXACT [] is_a: ECAO:0107290 ! podia relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107310 name: disk of primary podia is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage relationship: part_of ECAO:0107300 ! primary podia property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107320 name: secondary podia synonym: "secondary tube foot" EXACT [] is_a: ECAO:0107290 ! podia relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107330 name: disk of secondary podia is_a: ECAO:0104060 ! skeletal element relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107320 ! secondary podia property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107340 name: buccal podia is_a: ECAO:0104990 ! primary podia associated neuron relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107200 ! appendage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107350 name: spine synonym: "spine appendage" EXACT [] xref: UBERON:0008260 is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000500 ! 8-arm pluteus larva stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107360 name: juvenile spine synonym: "splayed spines" EXACT [] is_a: ECAO:0107350 ! spine relationship: existence_ends_during ECAO:0000560 ! late juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107370 name: definitive spine synonym: "adult spine" EXACT [] is_a: ECAO:0107350 ! spine property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107380 name: sphaeridium is_a: ECAO:0107200 ! appendage relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107390 name: ampulla synonym: "tube foot ampulla" EXACT [] xref: UBERON:0008252 is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106980 ! radial canal relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107400 name: adult mouth is_a: ECAO:0105970 ! mouth relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107410 name: adult anus is_a: ECAO:0105990 ! anus relationship: existence_starts_during ECAO:0000560 ! late juvenile stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107418 name: Aristotles lantern xref: UBERON:0008253 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103610 ! digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107420 name: tooth is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107418 ! Aristotles lantern property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107440 name: madreporite xref: UBERON:0009476 is_a: ECAO:0107190 ! genital plate is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0107260 ! genital plate CD relationship: existence_starts_during ECAO:0000550 ! early juvenile stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107450 name: gonopore synonym: "genital pore" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0107190 ! genital plate property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107460 name: gonad xref: UBERON:0000991 is_a: ECAO:0104100 ! adult structure relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103710 ! reproductive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107470 name: ovary xref: UBERON:0000992 is_a: ECAO:0107460 ! gonad property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107480 name: testis xref: UBERON:0000473 is_a: ECAO:0107460 ! gonad property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107490 name: juvenile digestive tract is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000560 ! late juvenile stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103640 ! juvenile digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107510 name: adult digestive tract is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103630 ! larval digestive system relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000580 ! adult stage relationship: part_of ECAO:0103650 ! adult digestive system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107520 name: mesentery xref: UBERON:0002095 is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107530 name: perivisceral cavity is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107540 name: photosensory cell synonym: "photoreceptor cell" EXACT [] is_a: ECAO:0104030 ! cell relationship: existence_starts_during ECAO:0000550 ! early juvenile stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107560 name: embryonic territory def: "A population of embryonic cells that share a common developmental fate or program of gene expression and comprising a region that lacks clear morphological boundaries" [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103530 ! anatomical region relationship: existence_ends_during ECAO:0000610 ! open mouth stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107570 name: adult organism def: "A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage." [] xref: UBERON:0007023 is_a: ECAO:0103560 ! multicellular organism is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103580 ! larva relationship: existence_starts_during ECAO:0000580 ! adult stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107580 name: embryonic muscular system def: "The muscle system of the embryo." [] is_a: ECAO:0103770 ! muscular system relationship: existence_ends_during ECAO:0000610 ! open mouth stage relationship: existence_starts_during ECAO:0000640 ! early pluteus stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107590 name: extracellular matrix def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [] is_a: ECAO:0104270 ! acellular membrane relationship: existence_ends_during ECAO:0000580 ! adult stage relationship: existence_starts_during ECAO:0000140 ! 1-cell stage relationship: part_of ECAO:0103550 ! whole organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107600 name: blastomere of 8-cell embryo def: "A blastomere of an 8-cell embryo." [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000180 ! 8-cell stage relationship: existence_starts_during ECAO:0000180 ! 8-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107610 name: blastomere of 16-cell embryo def: "A blastomere of a 16-cell embryo." [] is_a: ECAO:0104630 ! blastomere relationship: existence_ends_during ECAO:0000190 ! 16-cell stage relationship: existence_starts_during ECAO:0000190 ! 16-cell stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107620 name: presumptive animal pole domain neuron def: "A cell that will develop into a neuron of the animal pole domain." [] synonym: " animal pole domain neuronal progenitor cell" EXACT [] synonym: "apical pole domain presumptive neuron" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107630 name: presumptive ectoderm neuron def: "An ectodermal cell that will develop into a neuron." [] synonym: "ectoderm neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000630 ! late prism stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107640 name: presumptive ciliary band neuron def: "A cell that will develop into a neuron of the ciliary band." [] synonym: "ciliary band neuronal progenitor cell" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000630 ! late prism stage relationship: existence_starts_during ECAO:0000620 ! early prism stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107650 name: presumptive endoderm-associated neuron def: "An endodermal cell that will develop into a neuron." [] synonym: " endoderm-ssociated neuronal progenitor cell" EXACT [] synonym: "presumptive endodermal neuron" EXACT [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000410 ! late gastrula stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107660 name: postoral neuron def: "A neuron located near the base of an oral arm and outside the ciliary band." [] is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107670 name: presumptive postoral neuron def: "A cell that will give rise to a postoral neuron." [] is_a: ECAO:0104740 ! presumptive neuron relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107680 name: synaptotagmin-B-expressing neuron def: "A neuron that produces the synaptotagmin-B protein." [] synonym: " synaptotagmin-positive neuron" EXACT [] synonym: "synaptotagmin- B neuron" EXACT [] is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000530 ! adulthood relationship: existence_starts_during ECAO:0000410 ! late gastrula stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107690 name: nitric oxide synthase-expressing neuron def: "A neuron that produces the nitric oxide synthase protein." [] is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000530 ! adulthood relationship: existence_starts_during ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107700 name: cholinergic neuron def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [] is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000530 ! adulthood relationship: existence_starts_during ECAO:0000640 ! early pluteus stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107710 name: catecholaminergic/cholinergic neuron def: "A neuron that uses both acetylcholine and catecholamines as vesicular neurotransmitters." [] is_a: ECAO:0104790 ! neuron relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000640 ! early pluteus stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107720 name: endoderm-associated neuron def: "A neuron derived from endoderm." [] synonym: "endodermal neuron" EXACT [] is_a: ECAO:0104800 ! larval neuron relationship: develops_from ECAO:0104780 ! endoderm associated presumptive neuron relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107730 name: lateral ganglion def: "One of two bilateral ganglia that arise in the oral ectoderm near the ciliary band." [] is_a: ECAO:0104930 ! ganglion is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103970 ! animal pole domain relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage relationship: part_of ECAO:0103740 ! larval nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107740 name: right lateral ganglion def: "The lateral ganglion that forms on the right side of the embryo." [] is_a: ECAO:0107730 ! lateral ganglion property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107750 name: left lateral ganglion def: "The lateral ganglion that forms on the left side of the embryo." [] is_a: ECAO:0107730 ! lateral ganglion property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107760 name: presumptive ventral ectoderm def: "The part of the blastula that will give rise to ventral ectoderm." [] synonym: "presumptive oral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory relationship: existence_ends_during ECAO:0000400 ! mid-gastrula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107770 name: presumptive dorsal ectoderm def: "The part of the blastula that will give rise to dorsal ectoderm." [] synonym: "presumptive aboral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory relationship: existence_ends_during ECAO:0000400 ! mid-gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107780 name: anterior neuroectoderm def: "A dynamic terriritory within the prospective ectoderm of the early embryo, located at the anterior (animal) end of the embryo and shaped by Wnt signaling, that contains cells with neurogenic potential." [] synonym: " ANE" EXACT [] synonym: "animal ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000690 ! mesenchyme blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107790 name: equatorial ectoderm def: "A dynamic territory within the prospective ectoderm of the early embryo, located between the anterior neuroectoderm and the endomesoderm." [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000690 ! mesenchyme blastula stage relationship: existence_starts_during ECAO:0000230 ! 60-cell stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107800 name: inner anterior neuroectoderm def: "The innermost part of the anterior neuroectoderm, immediately surrounding the animal pole." [] synonym: " inner apical pole domain" EXACT [] synonym: "inner ANE" EXACT [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000630 ! late prism stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107810 name: outer anterior neuroectoderm def: "A torus shaped region comprising the outer part of the anterior neuroectoderm." [] synonym: " outer apical pole domain" EXACT [] synonym: "outer ANE" EXACT [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105070 ! animal tier 1 relationship: existence_ends_during ECAO:0000630 ! late prism stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0103970 ! animal pole domain property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107820 name: central ventral ectoderm def: "A region of the ectoderm derived from the animal hemisphere (i.e., mesomere descendants) and located just above the equator on the ventral side of the embryo." [] synonym: "central oral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107830 name: near apical ectoderm def: "A region of the ectoderm derived from the animal hemisphere (i.e., mesomere descendants) and located between the central ventral ectoderm and the animal pole domain on the ventral side of the embryo." [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000410 ! late gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0105200 ! ventral ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107840 name: lateral border ectoderm def: "A region of border ectoderm located on a lateral surface of the embryo." [] synonym: " lateral BE" EXACT [] synonym: "veg1 lateral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105220 ! ectoendoderm relationship: existence_ends_during ECAO:0000620 ! early prism stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105270 ! border ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107850 name: ventral border ectoderm def: "A region of border ectoderm located on the ventral side of the embryo." [] synonym: " oral BE" EXACT [] synonym: " oral border ectoderm" EXACT [] synonym: " ventral BE" EXACT [] synonym: "veg1 oral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105220 ! ectoendoderm relationship: existence_ends_during ECAO:0000620 ! early prism stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105270 ! border ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107860 name: dorsal border ectoderm def: "A region of border ectoderm located on the dorsal side of the embryo." [] synonym: " aboral BE" EXACT [] synonym: " aboral border ectoderm" EXACT [] synonym: " dorsal BE" EXACT [] synonym: "veg1 aboral ectoderm" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105220 ! ectoendoderm relationship: existence_ends_during ECAO:0000620 ! early prism stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105270 ! border ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107870 name: animal lateral ectoderm def: "A region of ectoderm derived from the animal hemisphere and located laterally at the boundary between hte ventral and dorsal ectoderm; this region overlaps with part of the prospective ciliary band." [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107880 name: right animal lateral ectoderm def: "The animal lateral ectoderm on the right side of the embryo." [] is_a: ECAO:0105320 ! lateral ectoderm is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107890 name: left animal lateral ectoderm def: "The animal lateral ectoderm on the left side of the embryo." [] is_a: ECAO:0105320 ! lateral ectoderm is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103890 ! animal hemisphere relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0105160 ! presumptive ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107900 name: postoral arm tip ectoderm def: "A portion of the ectoderm located at the tip of a postoral arm." [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage relationship: part_of ECAO:0105350 ! arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107910 name: right postoral arm tip ectoderm def: "A portion of the ectoderm located at the tip of the right postoral arm." [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage relationship: part_of ECAO:0107900 ! postoral arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107920 name: left postoral arm tip ectoderm def: "A portion of the ectoderm located at the tip of the left postoral arm." [] is_a: ECAO:0103530 ! anatomical region is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105270 ! border ectoderm relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage relationship: part_of ECAO:0107900 ! postoral arm tip ectoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107930 name: presumptive ciliary band def: "The cells that will give rise to the ciliary band." [] synonym: "presumptive ciliated band" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104908 ! ectoderm relationship: existence_ends_during ECAO:0000640 ! early pluteus stage relationship: existence_starts_during ECAO:0000690 ! mesenchyme blastula stage relationship: part_of ECAO:0103730 ! embryonic nervous system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107940 name: arm def: "An elongated extension of the embryo on the ventral side, supported by a simple or fenestrated skeletal rod and often covered in part by a ciliary band. Arms develop in bilaterally symmetrical pairs." [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103510 ! anatomical structure relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000610 ! open mouth stage relationship: part_of ECAO:0103560 ! multicellular organism property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107950 name: anterolateral arm def: "A type of arm that projects from the oral hood; forms after the postoral arms appear and prior to the appearance of the preoral and posterodorsal arms." [] is_a: ECAO:0107940 ! arm relationship: existence_starts_during ECAO:0000440 ! larval development relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107960 name: postoral arm def: "A type of arm that forms between the equator and the posterior pole, near the position of the skeletal rudiment; the first type of arm to appear." [] is_a: ECAO:0107940 ! arm relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107970 name: anterolateral rod def: "A rod that forms by the branching or pronounced curving of the anterior tip of a dorsoventral connecting rod and that projects ventrally from the oral hood, supporting an anterolateral arm." [] is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0107990 ! dorsoventral connecting rod relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107980 name: postoral rod def: "A rod that forms by the branching of the anonymous rod and projects ventrally, supporting a postoral arm." [] is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105710 ! anonymous rod relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0107990 name: dorsoventral connecting rod def: "A rod that initially forms as one of the three arms of the embryonic triradiate spicule rudiment; this rod extends toward the animal pole before branching or curving to form the anterolateral rod and, in some species, the recurrent rod." [] is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105630 ! spicule granule relationship: existence_ends_during ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108000 name: ventral transverse rod def: "A rod that initially forms as one of the three arms of the embryonic triradiate spicule rudiment; this rod projects toward the ventral midline and ceases growth early in development without branching." [] is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0105630 ! spicule granule relationship: existence_ends_during ECAO:0000440 ! larval development property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108010 name: distal tip of body rod def: "The growing tip of the body rod as it extends dorsally." [] is_a: ECAO:0104060 ! skeletal element relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage relationship: part_of ECAO:0105880 ! body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108020 name: distal tip of right body rod def: "The distal tip of the body rod that forms on the right side of the embryo." [] is_a: ECAO:0105868 ! posterior tip of body rod relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage relationship: part_of ECAO:0105890 ! left body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108030 name: distal tip of left body rod def: "The distal tip of the body rod that forms on the left side of the embryo.." [] is_a: ECAO:0105868 ! posterior tip of body rod relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage relationship: part_of ECAO:0105900 ! right body rod property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108040 name: recurrent rod def: "A rod that forms from the branching of a dorsoventral transverse rod and extends dorsally." [] is_a: ECAO:0105700 ! skeletal rod relationship: develops_from ECAO:0107990 ! dorsoventral connecting rod relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000630 ! late prism stage property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108050 name: presumptive embryonic skeletogenic mesoderm def: "The part of the embryonic presumptive mesoderm that will later give rise to the skeletogenic mesenchyme and embryonic skeleton." [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000600 ! vegetal plate stage relationship: existence_starts_during ECAO:0000210 ! 32-cell stage relationship: part_of ECAO:0106200 ! presumptive mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108060 name: ventrolateral skeletogenic mesenchyme cluster def: "A cluster of skeletogenic cell bodies that forms in the ventrolateral region of the subequatorial skeletogenic mesenchyme ring; one triradiate spicule rudiment will form in each of two ventrolateral clusters." [] is_a: ECAO:0104070 ! embryonic structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0105698 ! embryonic skeletogenic mesenchyme relationship: existence_ends_during ECAO:0000620 ! early prism stage relationship: existence_starts_during ECAO:0000400 ! mid-gastrula stage relationship: part_of ECAO:0106270 ! subequatorial skeletogenic mesenchyme ring property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108070 name: presumptive embryonic non-skeletogenic mesoderm def: "Embryonic cells tin the epithelial wall of the vegetal plate or the archenteron that will give rise to mesodermal derivatives other than skeleton." [] synonym: "NSM" EXACT [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000620 ! early prism stage relationship: existence_starts_during ECAO:0000280 ! late blastula stage relationship: part_of ECAO:0106200 ! presumptive mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108080 name: ventral presumptive embryonic non-skeletogenic mesoderm def: "The presumptive embryonic non-skeletogenic mesoderm on the ventral side of the embryo." [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0108070 ! presumptive embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108090 name: dorsal presumptive embryonic non-skeletogenic mesoderm def: "The presumptive embryonic non-skeletogenic mesoderm on the dorsal side of the embryo." [] is_a: ECAO:0107560 ! embryonic territory is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0103900 ! vegetal hemisphere relationship: existence_ends_during ECAO:0000390 ! early gastrula stage relationship: existence_starts_during ECAO:0000600 ! vegetal plate stage relationship: part_of ECAO:0108070 ! presumptive embryonic non-skeletogenic mesoderm property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108100 name: presumptive muscle cell def: "A cell that will give rise to a muscle cell." [] synonym: "muscle precursor cell" EXACT [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0104020 ! vegetal plate relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000620 ! early prism stage relationship: part_of ECAO:0103770 ! muscular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108110 name: muscle cell def: "A cell that is part of a muscle." [] is_a: ECAO:0104030 ! cell is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0108100 ! presumptive muscle cell relationship: existence_ends_during ECAO:0000530 ! adulthood relationship: existence_starts_during ECAO:0000640 ! early pluteus stage relationship: part_of ECAO:0106550 ! muscle property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108120 name: presumptive blastocoel def: "The inner, extracellular space between blastomeres of the cleavage stage embryo that will gradually expand and form the blastocoel." [] is_a: BFO:0000004 ! independent continuant is_a: ECAO:0103540 ! anatomical space relationship: existence_ends_during ECAO:0000230 ! 60-cell stage relationship: existence_starts_during ECAO:0000200 ! 28-cell stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108130 name: pyloric sphincter muscle cell def: "A cell that is part of the pyloric sphincter." [] is_a: ECAO:0106660 ! sphincter muscle cell relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000610 ! open mouth stage relationship: part_of ECAO:0106620 ! pyloric sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108140 name: cardiac sphincter muscle cell def: "A cell that is part of the cardiac sphincter." [] is_a: ECAO:0106660 ! sphincter muscle cell relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000640 ! early pluteus stage relationship: part_of ECAO:0106630 ! cardiac sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108150 name: anal sphincter muscle cell def: "A cell that is part of the anal sphincter." [] synonym: "anal pore muscle cell" EXACT [] xref: UBERON:0004916 is_a: ECAO:0106660 ! sphincter muscle cell relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000640 ! early pluteus stage relationship: part_of ECAO:0106640 ! anal sphincter property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108160 name: primary pore canal rudiment def: "A strand of mesenchyme cells that extends from the left coelom to the ectoderm and that will give rise to the primary pore canal." [] synonym: "presumptive hydropore canal" EXACT [] is_a: ECAO:0103510 ! anatomical structure is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0106800 ! left coelomic pouch relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000610 ! open mouth stage relationship: part_of ECAO:0103870 ! water vascular system property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108170 name: posterior enterocoel def: "An evagination of the midgut that will contribute to the coelom." [] is_a: ECAO:0106770 ! coelom relationship: develops_from ECAO:0106070 ! midgut relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000670 ! late organogenesis stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108180 name: left anterior coelomic pouch def: "In species with a posterior enterocoel, the left coelomic pouch that evaginates from the unpaired coelomic pouch at the anterior end of the archenteron." [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000660 ! mid-organogenesis stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108190 name: right anterior coelomic pouch def: "In species with a posterior enterocoel, the right coelomic pouch that evaginates from the unpaired coelomic pouch at the anterior end of the archenteron." [] is_a: ECAO:0106770 ! coelom relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000660 ! mid-organogenesis stage relationship: part_of ECAO:0103570 ! embryo property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108200 name: preoral ciliary band def: "In species with two separate ciliary bands, a ciliary band that surrounds the anterior-ventral end of the embryo, anterior to the mouth." [] is_a: ECAO:0105460 ! ciliary band is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0107930 ! presumptive ciliary band relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000610 ! open mouth stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: ECAO:0108210 name: postoral ciliary band def: "In species with two separate ciliary bands, a ciliary band that surrounds the posterior-dorsal end of the embryo, posterior to the mouth." [] is_a: ECAO:0105460 ! ciliary band is_a: UBERON:0001062 ! anatomical entity relationship: develops_from ECAO:0107930 ! presumptive ciliary band relationship: existence_ends_during ECAO:0000440 ! larval development relationship: existence_starts_during ECAO:0000610 ! open mouth stage relationship: part_of ECAO:0103580 ! larva property_value: oio:hasOBONamespace "echinoderm_anatomy" xsd:string [Term] id: GO:0003674 name: gene product or complex activity name: molecular_function namespace: molecular_function alt_id: GO:0005554 def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. comment: This is the same as GO molecular function subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "molecular function" EXACT [] is_a: BFO:0000015 ! process disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological process [Term] id: GO:0003824 name: catalytic activity namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Enzyme is_a: GO:0003674 ! molecular_function [Term] id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 is_a: BFO:0000040 ! material entity disjoint_from: GO:0008150 ! biological process property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/17729 xsd:anyURI [Term] id: GO:0005622 name: intracellular anatomical structure namespace: cellular_component def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "internal to cell" EXACT [] synonym: "intracellular" EXACT [] synonym: "nucleocytoplasm" RELATED [GOC:mah] synonym: "protoplasm" EXACT [] synonym: "protoplast" RELATED [GOC:mah] xref: Wikipedia:Intracellular is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/17776 xsd:anyURI [Term] id: GO:0005634 name: nucleus namespace: cellular_component def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell nucleus" EXACT [] synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] xref: NIF_Subcellular:sao1702920020 xref: Wikipedia:Cell_nucleus is_a: GO:0043231 ! intracellular membrane-bounded organelle disjoint_from: GO:0005737 ! cytoplasm relationship: in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0005635 name: nuclear envelope namespace: cellular_component alt_id: GO:0005636 def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic subset: goslim_plant xref: Wikipedia:Nuclear_envelope is_a: GO:0031967 ! organelle envelope relationship: part_of GO:0005634 ! nucleus relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0005737 name: cytoplasm namespace: cellular_component def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/23023 xsd:anyURI [Term] id: GO:0005773 name: vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005886 name: plasma membrane namespace: cellular_component alt_id: GO:0005887 alt_id: GO:0005904 def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] synonym: "cytoplasmic membrane" EXACT [] synonym: "inner endospore membrane" NARROW [] synonym: "integral component of plasma membrane" NARROW [] synonym: "integral to plasma membrane" NARROW [] synonym: "juxtamembrane" BROAD [] synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah] synonym: "plasmalemma" EXACT [] xref: NIF_Subcellular:sao1663586795 xref: Wikipedia:Cell_membrane is_a: GO:0016020 ! membrane relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0005938 name: cell cortex namespace: cellular_component def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_yeast synonym: "cell periphery" RELATED [] synonym: "ectoplasm" NARROW [] synonym: "peripheral cytoplasm" RELATED [] xref: Wikipedia:Cell_cortex is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0071944 ! cell periphery relationship: part_of GO:0071944 ! cell periphery property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/26298 xsd:anyURI [Term] id: GO:0007275 name: multicellular organism development namespace: biological_process def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] comment: Note that this term was 'developmental process'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism relationship: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/21234 xsd:anyURI [Term] id: GO:0008150 name: biological process name: biological_process namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 alt_id: GO:0044699 def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] def: "A process that emerges from two or more causally-connected macromolecular activities and has evolved to achieve a biological objective." [] comment: A biological process is an evolved process comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast synonym: "biological process" EXACT [] synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process relationship: has_part GO:0003674 ! molecular_function property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/24968 xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z [Term] id: GO:0009790 name: embryo development namespace: biological_process alt_id: GO:0009795 def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] subset: gocheck_do_not_manually_annotate subset: goslim_chembl subset: goslim_plant synonym: "embryogenesis" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "embryonal development" EXACT [] xref: Wikipedia:Embryogenesis is_a: GO:0007275 ! multicellular organism development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000922 ! embryo relationship: results_in_development_of UBERON:0000922 ! embryo [Term] id: GO:0009791 name: post-embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0009987 name: cellular process namespace: biological_process alt_id: GO:0008151 alt_id: GO:0044763 alt_id: GO:0050875 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate subset: goslim_plant synonym: "cell growth and/or maintenance" NARROW [] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] synonym: "single-organism cellular process" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2012-12-11T16:56:55Z [Term] id: GO:0012505 name: endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] subset: goslim_candida subset: goslim_flybase_ribbon subset: goslim_yeast xref: Wikipedia:Endomembrane_system is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005773 ! vacuole relationship: has_part GO:0005886 ! plasma membrane relationship: part_of CL:0000000 ! cell [Term] id: GO:0016020 name: membrane namespace: cellular_component alt_id: GO:0016021 alt_id: GO:0098589 alt_id: GO:0098805 def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "integral component of membrane" NARROW [] synonym: "integral to membrane" NARROW [] synonym: "membrane region" NARROW [] synonym: "region of membrane" NARROW [] synonym: "transmembrane" RELATED [GOC:mah] synonym: "whole membrane" NARROW [] xref: Wikipedia:Biological_membrane xref: Wikipedia:Transmembrane_protein is_a: GO:0110165 ! cellular anatomical entity creation_date: 2014-03-06T11:37:54Z [Term] id: GO:0016301 name: kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_yeast synonym: "phosphokinase activity" EXACT [] xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups [Term] id: GO:0016740 name: transferase activity namespace: molecular_function def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_prokaryote subset: goslim_yeast xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. subset: goslim_chembl xref: EC:2.7.-.- is_a: GO:0016740 ! transferase activity [Term] id: GO:0030154 name: cell differentiation namespace: biological_process def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant xref: Wikipedia:Cellular_differentiation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: results_in_acquisition_of_features_of CL:0000000 ! cell relationship: results_in_acquisition_of_features_of CL:0000000 ! cell property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/24390 xsd:anyURI [Term] id: GO:0031090 name: organelle membrane namespace: cellular_component def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606] xref: NIF_Subcellular:sao830981606 is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031965 name: nuclear membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: NIF_Subcellular:sao1687101204 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005635 ! nuclear envelope [Term] id: GO:0031967 name: organelle envelope namespace: cellular_component def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] subset: goslim_mouse is_a: GO:0031975 ! envelope relationship: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0031975 name: envelope namespace: cellular_component def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0032501 name: multicellular organismal process namespace: biological_process alt_id: GO:0044707 alt_id: GO:0050874 def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "organismal physiological process" EXACT [] synonym: "single-multicellular organism process" RELATED [] is_a: GO:0008150 ! biological process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2012-09-19T16:07:47Z [Term] id: GO:0032502 name: developmental process namespace: biological_process alt_id: GO:0044767 def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_pir synonym: "development" NARROW [] synonym: "single-organism developmental process" RELATED [] is_a: GO:0008150 ! biological process created_by: jl creation_date: 2012-12-19T12:21:31Z [Term] id: GO:0043226 name: organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_chembl subset: goslim_generic subset: goslim_pir subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0043227 name: membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] synonym: "membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao414196390 is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: has_part GO:0016020 ! membrane relationship: has_part GO:0016020 ! membrane [Term] id: GO:0043229 name: intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure relationship: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043231 name: intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir synonym: "intracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0048468 name: cell development namespace: biological_process def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] subset: goslim_candida synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0008150 ! biological process intersection_of: results_in_development_of CL:0000000 ! cell relationship: part_of GO:0030154 ! cell differentiation relationship: results_in_development_of CL:0000000 ! cell property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/24390 xsd:anyURI [Term] id: GO:0048513 name: animal organ development namespace: biological_process def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] synonym: "development of an organ" EXACT [] synonym: "organogenesis" EXACT [] xref: Wikipedia:Organogenesis is_a: GO:0048856 ! anatomical structure development property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/25943 xsd:anyURI [Term] id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant synonym: "development of an anatomical structure" EXACT [] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/26424 xsd:anyURI [Term] id: GO:0048869 name: cellular developmental process namespace: biological_process def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0009987 ! cellular process is_a: GO:0032502 ! developmental process [Term] id: GO:0071944 name: cell periphery namespace: cellular_component def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah creation_date: 2010-10-04T01:51:47Z [Term] id: GO:0098590 name: plasma membrane region namespace: cellular_component def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. subset: gocheck_do_not_manually_annotate synonym: "region of plasma membrane" EXACT [] is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane created_by: dos creation_date: 2014-03-06T11:55:32Z [Term] id: GO:0099568 name: cytoplasmic region namespace: cellular_component def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] subset: gocheck_do_not_annotate is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0099738 name: cell cortex region namespace: cellular_component def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] subset: gocheck_do_not_annotate synonym: "perimembrane region" EXACT [] is_a: GO:0005938 ! cell cortex is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005938 ! cell cortex intersection_of: part_of GO:0005938 ! cell cortex relationship: part_of GO:0005938 ! cell cortex [Term] id: GO:0110165 name: cellular anatomical entity namespace: cellular_component def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv] subset: gocheck_do_not_annotate subset: goslim_pir is_a: CARO:0000000 ! anatomical entity is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/24200 xsd:anyURI property_value: IAO:0000233 https://github.com/geneontology/go-ontology/issues/26424 xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z [Term] id: IAO:0000027 name: data item is_a: IAO:0000030 ! information content entity property_value: IAO:0000111 "data item" xsd:string [Term] id: IAO:0000030 name: information content entity is_a: BFO:0000031 ! generically dependent continuant property_value: IAO:0000111 "information content entity" xsd:string [Term] id: IAO:0000078 name: curation status specification def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "curation status specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string property_value: IAO:0000119 GROUP:OBI: xsd:string property_value: IAO:0000119 "OBI_0000266" xsd:string [Term] id: IAO:0000102 name: data about an ontology part def: "Data about an ontology part is a data item about a part of an ontology, for example a term" [] is_a: IAO:0000027 ! data item property_value: IAO:0000111 "data about an ontology part" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string [Term] id: IAO:0000225 name: obsolescence reason specification def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "obsolescence reason specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string [Term] id: IAO:0000409 name: denotator type def: "A denotator type indicates how a term should be interpreted from an ontological perspective." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "denotator type" xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string [Term] id: NCBITaxon:1 name: root namespace: ncbi_taxonomy synonym: "all" RELATED synonym [] xref: GC_ID:1 xref: PMID:30365038 xref: PMID:32761142 [Term] id: NCBITaxon:131567 name: cellular organisms namespace: ncbi_taxonomy synonym: "biota" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1 ! root [Term] id: NCBITaxon:147537 name: Saccharomycotina namespace: ncbi_taxonomy synonym: "true yeasts" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:716545 ! saccharomyceta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:147554 name: Schizosaccharomycetes namespace: ncbi_taxonomy synonym: "Archiascomycota" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:451866 ! Taphrinomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:2 name: Bacteria namespace: ncbi_taxonomy synonym: "bacteria" RELATED blast_name [] synonym: "eubacteria" EXACT genbank_common_name [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11542017 xref: PMID:11542087 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:7520741 xref: PMID:8123559 xref: PMID:8186100 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2157 ! Archaea disjoint_from: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:2157 name: Archaea namespace: ncbi_taxonomy synonym: "archaea" RELATED blast_name [] synonym: "Archaebacteria" RELATED synonym [] synonym: "Mendosicutes" RELATED synonym [] synonym: "Metabacteria" RELATED synonym [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11541975 xref: PMID:11542064 xref: PMID:11542149 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:25527841 xref: PMID:270744 xref: PMID:32628106 xref: PMID:36748408 xref: PMID:8123559 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms disjoint_from: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:2759 name: Eukaryota namespace: ncbi_taxonomy synonym: "Eucarya" RELATED synonym [] synonym: "Eucaryotae" RELATED synonym [] synonym: "eucaryotes" EXACT genbank_common_name [] synonym: "Eukarya" RELATED synonym [] synonym: "Eukaryotae" RELATED synonym [] synonym: "eukaryotes" EXACT OMO:0003003 [] synonym: "eukaryotes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: has_rank NCBITaxon:superkingdom [Term] id: NCBITaxon:33154 name: Opisthokonta namespace: ncbi_taxonomy synonym: "Fungi/Metazoa group" RELATED synonym [] synonym: "opisthokonts" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33208 name: Metazoa namespace: ncbi_taxonomy synonym: "Animalia" RELATED synonym [] synonym: "animals" RELATED blast_name [] synonym: "metazoans" EXACT genbank_common_name [] synonym: "multicellular animals" EXACT OMO:0003003 [] xref: GC_ID:1 is_a: NCBITaxon:33154 ! Opisthokonta disjoint_from: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:33213 name: Bilateria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:34346 name: Schizosaccharomycetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:147554 ! Schizosaccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:451864 name: Dikarya namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15689432 xref: PMID:16151185 xref: PMID:17010206 xref: PMID:17051209 xref: PMID:17572334 is_a: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:subkingdom [Term] id: NCBITaxon:451866 name: Taphrinomycotina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota disjoint_from: NCBITaxon:716545 ! saccharomyceta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:4751 name: Fungi namespace: ncbi_taxonomy synonym: "fungi" RELATED blast_name [] synonym: "Mycota" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:12684019 is_a: NCBITaxon:33154 ! Opisthokonta property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:4890 name: Ascomycota namespace: ncbi_taxonomy synonym: "ascomycete fungi" RELATED blast_name [] synonym: "ascomycetes" EXACT genbank_common_name [] synonym: "sac fungi" EXACT OMO:0003003 [] xref: GC_ID:1 xref: PMID:17572334 is_a: NCBITaxon:451864 ! Dikarya property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:4891 name: Saccharomycetes namespace: ncbi_taxonomy synonym: "Hemiascomycetes" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:147537 ! Saccharomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:4892 name: Saccharomycetales namespace: ncbi_taxonomy synonym: "budding yeasts" RELATED blast_name [] synonym: "Endomycetales" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4891 ! Saccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:4893 name: Saccharomycetaceae namespace: ncbi_taxonomy alt_id: NCBITaxon:221665 alt_id: NCBITaxon:44280 xref: GC_ID:1 is_a: NCBITaxon:4892 ! Saccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4894 name: Schizosaccharomycetaceae namespace: ncbi_taxonomy synonym: "fission yeasts" EXACT genbank_common_name [] synonym: "Schizosaccharomycetoideae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:34346 ! Schizosaccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4895 name: Schizosaccharomyces namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4894 ! Schizosaccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4896 name: Schizosaccharomyces pombe namespace: ncbi_taxonomy alt_id: NCBITaxon:45042 synonym: "fission yeast" EXACT genbank_common_name [] synonym: "Schizosaccharomyces malidevorans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4895 ! Schizosaccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:4930 name: Saccharomyces namespace: ncbi_taxonomy alt_id: NCBITaxon:36915 synonym: "Pachytichospora" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4893 ! Saccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4932 name: Saccharomyces cerevisiae namespace: ncbi_taxonomy alt_id: NCBITaxon:41870 synonym: "baker's yeast" EXACT OMO:0003003 [] synonym: "brewer's yeast" EXACT genbank_common_name [] synonym: "Candida robusta" RELATED synonym [] synonym: "Mycoderma cerevisiae" RELATED synonym [] synonym: "Saccharomyces capensis" RELATED synonym [] synonym: "Saccharomyces cerevisiae 'var. diastaticus'" EXACT equivalent_name [] synonym: "Saccharomyces diastaticus" RELATED synonym [] synonym: "Saccharomyces italicus" RELATED synonym [] synonym: "Saccharomyces oviformis" RELATED synonym [] synonym: "Saccharomyces uvarum var. melibiosus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4930 ! Saccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:6072 name: Eumetazoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:716545 name: saccharomyceta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota property_value: has_rank NCBITaxon:clade [Term] id: PATO:0000001 name: quality namespace: quality alt_id: PATO:0000072 def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG] is_a: BFO:0000020 ! characteristic [Term] id: PATO:0001241 name: physical object quality namespace: quality alt_id: PATO:0001237 alt_id: PATO:0001238 def: "A quality which inheres in a continuant." [PATOC:GVG] comment: Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles. synonym: "monadic quality of a continuant" EXACT [] synonym: "monadic quality of an object" NARROW [] synonym: "monadic quality of continuant" NARROW [] synonym: "multiply inhering quality of a physical entity" EXACT [] synonym: "quality of a continuant" EXACT [] synonym: "quality of a single physical entity" EXACT [] synonym: "quality of an object" EXACT [] synonym: "quality of continuant" EXACT [] xref: snap:Quality is_a: PATO:0000001 ! quality [Term] id: PATO:0001396 name: cellular quality namespace: quality def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG] is_a: PATO:0070044 ! anatomical structure quality [Term] id: PATO:0001404 name: nucleate quality namespace: quality def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001405 name: anucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality [Term] id: PATO:0001406 name: binucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001908 ! multinucleate [Term] id: PATO:0001407 name: mononucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001908 name: multinucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001992 name: cellularity namespace: quality def: "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." [PATOC:GVG] subset: attribute_slim subset: scalar_slim is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0001993 name: multicellular namespace: quality def: "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." [PATOC:GVG] subset: value_slim is_a: PATO:0001992 ! cellularity [Term] id: PATO:0001995 name: organismal quality namespace: quality def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0002505 name: nucleated namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-10-21T05:44:34Z [Term] id: PATO:0070044 name: anatomical structure quality namespace: quality def: "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." [] is_a: PATO:0001241 ! physical object quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: UBERON:0000000 name: processual entity namespace: uberon def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] subset: common_anatomy subset: upper_level xref: BFO:0000003 is_a: BFO:0000003 ! occurrent disjoint_from: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000061 name: anatomical structure namespace: uberon def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003] subset: common_anatomy subset: upper_level synonym: "biological structure" EXACT [] synonym: "connected biological structure" EXACT [CARO:0000003] xref: AAO:0010825 xref: AEO:0000003 xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 xref: FBbt:00007001 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 xref: HAO:0000003 xref: http://dbpedia.org/ontology/AnatomicalStructure xref: MA:0003000 xref: MESH:D000825 xref: SCTID:362889002 xref: TAO:0000037 xref: TGMA:0001823 xref: VHOG:0001759 xref: XAO:0003000 xref: ZFA:0000037 is_a: UBERON:0000465 ! material anatomical entity relationship: existence_ends_during_or_before UBERON:0000071 ! death stage relationship: existence_starts_during_or_after UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000066 name: fully formed stage namespace: uberon def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "adult stage" BROAD [] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] xref: BilaDO:0000004 xref: BTO:0001043 xref: EFO:0001272 xref: FBdv:00005369 xref: WBls:0000041 xref: XtroDO:0000084 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: preceded_by UBERON:0000111 ! organogenesis stage relationship: precedes UBERON:0000071 ! death stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/566 xsd:anyURI [Term] id: UBERON:0000068 name: embryo stage namespace: uberon def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165] synonym: "embryogenesis" RELATED [] synonym: "embryonic stage" EXACT [] xref: BilaDO:0000002 xref: EV:0300001 xref: FBdv:00005289 xref: FMA:72652 xref: HsapDv:0000002 xref: MmusDv:0000002 xref: OGES:000000 xref: OGES:000022 xref: SCTID:296280003 xref: WBls:0000003 xref: WBls:0000092 xref: WBls:0000102 xref: XAO:1000012 is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000092 ! post-embryonic stage relationship: precedes UBERON:0000066 ! fully formed stage relationship: precedes UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0009790 ! embryo development [Term] id: UBERON:0000071 name: death stage namespace: uberon def: "End of the life of an organism." [XAO:0000437] subset: common_anatomy synonym: "death" RELATED [] xref: XAO:0000437 xref: XtroDO:0000085 is_a: UBERON:0000105 ! life cycle stage relationship: ends UBERON:0000104 ! life cycle property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "ncit:Death is an outcome" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0000092 name: post-embryonic stage namespace: uberon def: "Stage succeeding embryo, including mature structure." [https://orcid.org/0000-0002-6601-2165] synonym: "post-hatching stage" NARROW [] synonym: "postembryonic" RELATED [] synonym: "postembryonic stage" EXACT [] xref: BilaDO:0000003 xref: OGES:000010 xref: OGES:000014 xref: OGES:000024 xref: WBls:0000022 xref: WBls:0000093 xref: WBls:0000103 is_a: UBERON:0000105 ! life cycle stage relationship: preceded_by UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0009791 ! post-embryonic development property_value: seeAlso https://github.com/obophenotype/uberon/issues/344 xsd:anyURI property_value: UBPROP:0000008 "In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997)" xsd:string [Term] id: UBERON:0000104 name: life cycle namespace: uberon def: "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: upper_level synonym: "entire life cycle" EXACT [] synonym: "entire lifespan" EXACT [] synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv:00000000 xref: HsapDv:0000001 xref: MmusDv:0000001 xref: ncithesaurus:Life xref: OGES:000011 is_a: UBERON:0000000 ! processual entity relationship: ends_with UBERON:0000071 ! death stage relationship: has_part UBERON:0000105 ! life cycle stage relationship: starts_with UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: seeAlso https://github.com/obophenotype/uberon/issues/532 xsd:anyURI [Term] id: UBERON:0000105 name: life cycle stage namespace: uberon def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: efo_slim subset: upper_level synonym: "developmental stage" NARROW [] synonym: "stage" NARROW [] xref: BILS:0000105 xref: EFO:0000399 xref: FBdv:00007012 xref: FMA:24120 xref: HsapDv:0000000 xref: MESH:D008018 xref: MmusDv:0000000 xref: ncithesaurus:Developmental_Stage xref: OlatDv:0000010 xref: PdumDv:0000090 xref: WBls:0000002 xref: XAO:1000000 xref: ZFS:0000000 xref: ZFS:0100000 is_a: UBERON:0000000 ! processual entity relationship: part_of UBERON:0000104 ! life cycle property_value: IAO:0000116 "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages" xsd:string property_value: UBPROP:0000012 "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" xsd:string [Term] id: UBERON:0000106 name: zygote stage namespace: uberon def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote] subset: efo_slim synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 xref: IDOMAL:0000302 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration", https://w3id.org/sssom/author_id="https://orcid.org/0000-0003-4423-4370", https://w3id.org/sssom/mapping_provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 xref: Wikipedia:Zygote xref: XAO:1000001 xref: ZFS:0000001 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: starts UBERON:0000104 ! life cycle property_value: seeAlso EMAPA:16033 property_value: UBPROP:0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000745", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000111 name: organogenesis stage namespace: uberon def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis] synonym: "segmentation stage" RELATED [] xref: BilaDO:0000010 xref: BILS:0000111 xref: HsapDv:0000015 xref: MmusDv:0000018 xref: OGES:000005 xref: OGES:000032 xref: Wikipedia:Organogenesis is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0048513 ! animal organ development property_value: seeAlso https://github.com/obophenotype/developmental-stage-ontologies/issues/84 xsd:anyURI property_value: seeAlso https://github.com/obophenotype/uberon/issues/533 xsd:anyURI [Term] id: UBERON:0000465 name: material anatomical entity namespace: uberon def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level xref: AAO:0010264 xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 xref: FBbt:00007016 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 xref: TGMA:0001826 xref: VHOG:0001721 is_a: BFO:0000040 ! material entity is_a: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000468 name: multicellular organism namespace: uberon def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, http://orcid.org/0000-0001-9114-8737, Wikipedia:Multi-cellular_organism] subset: common_anatomy subset: efo_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "body" RELATED [AEO:0000103, BIRNLEX:18, FMA:256135, NCIT:C13041] synonym: "Koerper" RELATED [BTO:0001489] synonym: "multi-cellular organism" EXACT [CARO:0000012] synonym: "organism" BROAD [FBbt:00000001, VHOG:0000671, WBbt:0007833] synonym: "whole body" RELATED [BTO:0001489] synonym: "whole organism" RELATED [FBbt:00000001] xref: AAO:0010026 xref: AEO:0000191 xref: BILA:0000012 xref: BIRNLEX:18 xref: BSA:0000038 xref: BTO:0000042 xref: CARO:0000012 xref: EFO:0002906 xref: EHDAA2:0003103 xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 xref: FBbt:00000001 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 xref: NCIT:C13041 xref: ncithesaurus:Whole_Organism xref: SCTID:243928005 xref: TADS:0000001 xref: TAO:0001094 xref: TGMA:0001832 xref: VHOG:0000671 xref: WBbt:0007833 xref: Wikipedia:Multi-cellular_organism xref: XAO:0003004 xref: ZFA:0001094 is_a: UBERON:0010000 ! multicellular anatomical structure property_value: IAO:0000116 "TODO - split body and mc organism? body continues after death stage" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000007 "organismal" xsd:string [Term] id: UBERON:0000922 name: embryo namespace: uberon def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "developing organism" RELATED [BILA:0000056] synonym: "developmental tissue" RELATED [] synonym: "embryonic organism" EXACT [BILA:0000056] xref: AAO:0011035 xref: AEO:0000169 xref: BILA:0000056 xref: BSA:0000039 xref: BTO:0000379 xref: CALOHA:TS-0229 xref: EFO:0001367 xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 xref: FBbt:00000052 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism xref: IDOMAL:0000646 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration", https://w3id.org/sssom/author_id="https://orcid.org/0000-0003-4423-4370", https://w3id.org/sssom/mapping_provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 xref: NCIT:C28147 xref: OGEM:000001 xref: SCTID:57991002 xref: UMLS:C0013935 {source="ncithesaurus:Embryo"} xref: VHOG:0001766 xref: Wikipedia:Embryo xref: XAO:0000113 xref: ZFA:0000103 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000068 ! embryo stage intersection_of: existence_starts_with UBERON:0000068 ! embryo stage relationship: existence_ends_with UBERON:0000068 ! embryo stage relationship: existence_starts_with UBERON:0000068 ! embryo stage property_value: http://xmlns.com/foaf/0.1/depiction https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg xsd:anyURI property_value: seeAlso https://github.com/obophenotype/uberon/issues/503 xsd:anyURI property_value: UBPROP:0000007 "embryonic" xsd:string property_value: UBPROP:0000012 "Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level xref: AAO:0010841 xref: AEO:0000000 xref: BFO:0000004 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FBbt:10000000 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 is_a: BFO:0000004 ! independent continuant property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0009953 name: post-embryonic organism namespace: uberon def: "A multicellular organism that existence_starts_with a post-embryonic stage." [OBOL:automatic] synonym: "post-hatching organism" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "post-natal organism" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "postnatal mouse" NARROW [MA:0002405] synonym: "postnatal organism" EXACT [] synonym: "TS28 mouse" NARROW [MA:0002405] xref: MA:0002405 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_with UBERON:0000092 ! post-embryonic stage relationship: existence_starts_with UBERON:0000092 ! post-embryonic stage property_value: seeAlso https://github.com/obophenotype/uberon/issues/667 xsd:anyURI [Term] id: UBERON:0010000 name: multicellular anatomical structure namespace: uberon def: "An anatomical structure that has more than one cell as a part." [CARO:0010000] subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 xref: FBbt:00100313 {https://w3id.org/sssom/mapping_justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular relationship: has_part CL:0000000 ! cell relationship: has_quality PATO:0001993 ! multicellular property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0015212 name: lateral structure namespace: uberon def: "Any structure that is placed on one side of the left-right axis of a bilaterian." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: non_informative is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: in_lateral_side_of UBERON:0000465 ! material anatomical entity relationship: in_lateral_side_of UBERON:0000465 ! material anatomical entity relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0000465 ! material anatomical entity property_value: IAO:0000232 "This class is primarily to implement taxon constraints. It may be removed in the future." xsd:string [Typedef] id: acts_upstream_of name: acts upstream of def: "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0002263 property_value: IAO:0000112 "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." xsd:string property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of holds_over_chain: enables causally_upstream_of is_a: acts_upstream_of_or_within ! acts upstream of or within [Typedef] id: acts_upstream_of,_negative_effect name: acts upstream of, negative effect def: "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004035 property_value: RO:0004050 RO:0002263 property_value: seeAlso https://wiki.geneontology.org/Acts_upstream_of,_negative_effect xsd:anyURI holds_over_chain: enables causally_upstream_of,_negative_effect is_a: acts_upstream_of ! acts upstream of is_a: acts_upstream_of_or_within,_negative_effect ! acts upstream of or within, negative effect created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:22Z [Typedef] id: acts_upstream_of,_positive_effect name: acts upstream of, positive effect def: "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004034 property_value: RO:0004049 RO:0002263 property_value: seeAlso https://wiki.geneontology.org/Acts_upstream_of,_positive_effect xsd:anyURI holds_over_chain: enables causally_upstream_of,_positive_effect is_a: acts_upstream_of ! acts upstream of is_a: acts_upstream_of_or_within,_positive_effect ! acts upstream of or within, positive effect created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:14Z [Typedef] id: acts_upstream_of_or_within name: acts upstream of or within def: "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term synonym: "affects" RELATED [] xref: RO:0002264 property_value: IAO:0000112 "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." xsd:string property_value: seeAlso https://wiki.geneontology.org/Acts_upstream_of_or_within xsd:anyURI holds_over_chain: enables causally_upstream_of_or_within is_a: causal_agent_in_process ! causal agent in process [Typedef] id: acts_upstream_of_or_within,_negative_effect name: acts upstream of or within, negative effect subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004033 property_value: RO:0004050 RO:0002264 property_value: seeAlso https://wiki.geneontology.org/Acts_upstream_of_or_within,_negative_effect xsd:anyURI holds_over_chain: enables causally_upstream_of_or_within,_negative_effect is_a: acts_upstream_of_or_within ! acts upstream of or within created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:51Z [Typedef] id: acts_upstream_of_or_within,_positive_effect name: acts upstream of or within, positive effect subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004032 property_value: RO:0004049 RO:0002264 property_value: seeAlso https://wiki.geneontology.org/Acts_upstream_of_or_within,_positive_effect xsd:anyURI holds_over_chain: enables causally_upstream_of_or_within,_positive_effect is_a: acts_upstream_of_or_within ! acts upstream of or within created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:30Z [Typedef] id: before_or_simultaneous_with name: before or simultaneous with comment: Primitive instance level timing relation between events subset: ro-eco xref: RO:0002081 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "<=" xsd:string is_a: temporally_related_to ! temporally related to [Typedef] id: capable_of name: capable of namespace: uberon def: "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " [] subset: ro-eco xref: RO:0002215 property_value: IAO:0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" xsd:string property_value: IAO:0000112 "osteoclast SubClassOf 'capable of' some 'bone resorption'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function realized in" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20123131 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/21208450 property_value: IAO:0000232 "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000015 ! process is_a: capable_of_part_of ! capable of part of [Typedef] id: capable_of_negatively_regulating name: capable of negatively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." [] xref: RO:0002597 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: capable_of negatively_regulates is_a: capable_of_regulating ! capable of regulating [Typedef] id: capable_of_part_of name: capable of part of namespace: uberon def: "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." [] xref: RO:0002216 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function in" xsd:string property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/ holds_over_chain: capable_of part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: causal_agent_in_process ! causal agent in process is_a: functionally_related_to ! functionally related to [Typedef] id: capable_of_positively_regulating name: capable of positively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." [] xref: RO:0002598 property_value: IAO:0000112 "renin -> arteriolar smooth muscle contraction" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: capable_of positively_regulates is_a: capable_of_regulating ! capable of regulating [Typedef] id: capable_of_regulating name: capable of regulating def: "Holds between c and p if and only if c is capable of some activity a, and a regulates p." [] xref: RO:0002596 property_value: IAO:0000112 "pyrethroid -> growth" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations holds_over_chain: capable_of regulates is_a: causal_agent_in_process ! causal agent in process [Typedef] id: causal_agent_in_process name: causal agent in process def: "A relationship between a material entity and a process where the material entity has some causal role that influences the process" [] xref: RO:0002500 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process inverse_of: process_has_causal_agent ! process has causal agent [Typedef] id: causal_relation_between_entities name: causal relation between entities xref: RO:0002506 property_value: IAO:0000116 "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: causally_related_to ! causally related to [Typedef] id: causal_relation_between_material_entity_and_a_process name: causal relation between material entity and a process def: "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." [] xref: RO:0002595 property_value: IAO:0000116 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations domain: BFO:0000040 ! material entity range: BFO:0000015 ! process is_a: causally_related_to ! causally related to [Typedef] id: causal_relation_between_processes name: causal relation between processes def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." [] xref: RO:0002501 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent is_a: causally_related_to ! causally related to [Typedef] id: causally_downstream_of name: causally downstream of def: "inverse of upstream of" [] xref: RO:0002404 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: causally_downstream_of_or_within ! causally downstream of or within is_a: preceded_by ! preceded by inverse_of: causally_upstream_of ! causally upstream of [Typedef] id: causally_downstream_of_or_within name: causally downstream of or within def: "inverse of causally upstream of or within" [] subset: RO:0002259 xref: RO:0002427 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_transitive: true is_a: causal_relation_between_processes ! causal relation between processes [Typedef] id: causally_influenced_by name: causally influenced by xref: RO:0002559 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influenced by (entity-centric)" xsd:string is_a: causal_relation_between_entities ! causal relation between entities inverse_of: causally_influences ! causally influences [Typedef] id: causally_influences name: causally influences def: "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." [] xref: RO:0002566 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influences (entity-centric)" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: causal_relation_between_entities ! causal relation between entities [Typedef] id: causally_related_to name: causally related to def: "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." [https://en.wikipedia.org/wiki/Causality] xref: RO:0002410 property_value: IAO:0000116 "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string [Typedef] id: causally_upstream_of name: causally upstream of def: "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002411 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: causally_upstream_of_or_within ! causally upstream of or within is_a: precedes ! precedes [Typedef] id: causally_upstream_of,_negative_effect name: causally upstream of, negative effect def: "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002305 property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: RO:0004050 RO:0002411 property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of,_negative_effect is_a: causally_upstream_of ! causally upstream of is_a: causally_upstream_of_or_within,_negative_effect ! causally upstream of or within, negative effect [Typedef] id: causally_upstream_of,_positive_effect name: causally upstream of, positive effect def: "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." [] comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002304 property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: RO:0004049 RO:0002411 property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of,_positive_effect is_a: causally_upstream_of ! causally upstream of is_a: causally_upstream_of_or_within,_positive_effect ! causally upstream of or within, positive effect [Typedef] id: causally_upstream_of_or_within name: causally upstream of or within def: "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." [] synonym: "affects" RELATED [] xref: RO:0002418 property_value: IAO:0000116 "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "influences (processual)" xsd:string is_transitive: true is_a: causal_relation_between_processes ! causal relation between processes inverse_of: causally_downstream_of_or_within ! causally downstream of or within [Typedef] id: causally_upstream_of_or_within,_negative_effect name: causally upstream of or within, negative effect xref: RO:0004046 property_value: RO:0004050 RO:0002418 property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect xsd:anyURI is_a: causally_upstream_of_or_within ! causally upstream of or within created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:05Z [Typedef] id: causally_upstream_of_or_within,_positive_effect name: causally upstream of or within, positive effect xref: RO:0004047 property_value: RO:0004049 RO:0002418 property_value: seeAlso https://wiki.geneontology.org/Causally_upstream_of_or_within,_positive_effect is_a: causally_upstream_of_or_within ! causally upstream of or within created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:19Z [Typedef] id: characteristic_of name: characteristic of def: "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence." [] comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing. xref: RO:0000052 property_value: IAO:0000111 "inheres in" xsd:string property_value: IAO:0000112 "this fragility is a characteristic of this vase" xsd:string property_value: IAO:0000112 "this red color is a characteristic of this apple" xsd:string property_value: IAO:0000118 "inheres_in" xsd:string property_value: RO:0001900 RO:0001901 is_functional: true is_a: characteristic_of_part_of ! characteristic of part of inverse_of: has_characteristic ! has characteristic [Typedef] id: characteristic_of_part_of name: characteristic of part of def: "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." [] xref: RO:0002314 property_value: IAO:0000116 "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "inheres in part of" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 property_value: RO:0001900 RO:0001901 property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/ holds_over_chain: characteristic_of part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: depends_on ! depends on transitive_over: part_of ! part_of [Typedef] id: depends_on name: depends on xref: RO:0002502 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso BFO:0000169 [Typedef] id: developmentally_contributes_to name: developmentally contributes to def: "inverse of has developmental contribution from" [] subset: RO:0002259 xref: RO:0002255 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: develops_into part_of is_a: developmentally_succeeded_by ! developmentally succeeded by is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to [Typedef] id: developmentally_preceded_by name: developmentally preceded by def: "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" [] comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from xref: RO:0002258 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "false" xsd:boolean property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: developmentally_related_to ! developmentally related to inverse_of: developmentally_succeeded_by ! developmentally succeeded by [Typedef] id: developmentally_related_to name: developmentally related to def: "A relationship that holds between entities participating in some developmental process (GO:0032502)" [] xref: RO:0002324 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" xsd:string [Typedef] id: developmentally_succeeded_by name: developmentally succeeded by def: "Inverse of developmentally preceded by" [] xref: RO:0002286 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: develops_from name: develops from namespace: uberon def: "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" [] comment: This is the transitive form of the develops from relation xref: RO:0002202 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant is_transitive: true is_a: developmentally_preceded_by ! developmentally preceded by is_a: has_developmental_contribution_from ! has developmental contribution from inverse_of: develops_into ! develops into [Typedef] id: develops_into name: develops into namespace: uberon def: "inverse of develops from" [] subset: RO:0002259 xref: RO:0002203 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 is_transitive: true is_a: developmentally_succeeded_by ! developmentally succeeded by is_a: has_potential_to_develop_into ! has potential to develop into is_a: has_potential_to_directly_develop_into ! has potential to directly develop into [Typedef] id: device_utilizes_material name: device utilizes material def: "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." [] synonym: "utilizes" BROAD [] xref: RO:0017001 property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899 property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345 property_value: IAO:0000232 "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string property_value: IAO:0000232 "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string holds_over_chain: capable_of has_input creation_date: 2021-11-08T12:00:00Z [Typedef] id: directly_negatively_regulated_by name: directly negatively regulated by def: "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." [https://orcid.org/0000-0002-7073-9172] xref: RO:0002023 is_a: directly_regulated_by ! directly regulated by inverse_of: directly_negatively_regulates ! directly negatively regulates created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-09-17T13:52:38Z [Typedef] id: directly_negatively_regulates name: directly negatively regulates def: "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002630 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002578 property_value: seeAlso https://wiki.geneontology.org/Directly_negatively_regulates xsd:anyURI is_a: directly_regulates ! directly regulates is_a: negatively_regulates ! negatively regulates [Typedef] id: directly_negatively_regulates_activity_of name: directly negatively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." [] synonym: "molecularly decreases activity of" EXACT [] xref: RO:0002449 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly inhibits" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: directly_regulates_activity_of ! directly regulates activity of [Typedef] id: directly_positively_regulated_by name: directly positively regulated by def: "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." [https://orcid.org/0000-0002-7073-9172] xref: RO:0002024 is_a: directly_regulated_by ! directly regulated by inverse_of: directly_positively_regulates ! directly positively regulates created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-09-17T13:52:47Z [Typedef] id: directly_positively_regulates name: directly positively regulates def: "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002629 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002578 property_value: seeAlso https://wiki.geneontology.org/Directly_positively_regulates xsd:anyURI is_a: directly_regulates ! directly regulates is_a: positively_regulates ! positively regulates [Typedef] id: directly_positively_regulates_activity_of name: directly positively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." [] synonym: "molecularly increases activity of" EXACT [] xref: RO:0002450 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly activates" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: directly_regulates_activity_of ! directly regulates activity of [Typedef] id: directly_regulated_by name: directly regulated by comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. {xref="https://orcid.org/0000-0002-7073-9172"} xref: RO:0002022 is_a: regulated_by ! regulated by inverse_of: directly_regulates ! directly regulates created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-09-17T13:52:24Z [Typedef] id: directly_regulates name: directly regulates def: "p directly regulates q iff p is immediately causally upstream of q and p regulates q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002578 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly regulates (processual)" xsd:string property_value: RO:0002575 RO:0002211 is_a: immediately_causally_upstream_of ! immediately causally upstream of is_a: regulates ! regulates [Typedef] id: directly_regulates_activity_of name: directly regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." [] synonym: "molecularly controls" EXACT [] xref: RO:0002448 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: molecularly_interacts_with ! molecularly interacts with is_a: regulates_activity_of ! regulates activity of [Typedef] id: disposition_of name: disposition of def: "inverse of has disposition" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. subset: RO:0002259 xref: RO:0000092 is_a: characteristic_of ! characteristic of [Typedef] id: enabled_by name: enabled by def: "inverse of enables" [] subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002333 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso https://wiki.geneontology.org/Enabled_by xsd:anyURI is_a: functionally_related_to ! functionally related to is_a: has_participant ! has participant [Typedef] id: enables name: enables def: "c enables p iff c is capable of p and c acts to execute p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0002327 property_value: IAO:0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "catalyzes" xsd:string property_value: IAO:0000118 "executes" xsd:string property_value: IAO:0000118 "has" xsd:string property_value: IAO:0000118 "is catalyzing" xsd:string property_value: IAO:0000118 "is executing" xsd:string property_value: IAO:0000232 "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." xsd:string property_value: seeAlso https://wiki.geneontology.org/Enables xsd:anyURI is_a: capable_of ! capable of inverse_of: enabled_by ! enabled by transitive_over: has_component_activity ! has component activity transitive_over: has_part ! has part [Typedef] id: enables_subfunction name: enables subfunction def: "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." [] xref: RO:0004031 holds_over_chain: enables has_part is_a: functionally_related_to ! functionally related to created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-25T23:20:13Z [Typedef] id: ends name: ends namespace: uberon def: "inverse of ends with" [] subset: ro-eco xref: RO:0002229 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: part_of ! part_of is_a: temporally_related_to ! temporally related to inverse_of: ends_with ! ends with [Typedef] id: ends_after name: ends after comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) subset: ro-eco xref: RO:0002086 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string is_transitive: true is_a: temporally_related_to ! temporally related to [Typedef] id: ends_with name: ends with namespace: uberon def: "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: RO:0002230 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "finished by" xsd:string is_transitive: true is_a: has_part ! has part is_a: temporally_related_to ! temporally related to [Typedef] id: evolutionarily_related_to name: evolutionarily related to def: "A relationship that holds via some environmental process" [] xref: RO:0002320 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution." xsd:string [Typedef] id: existence_ends_during name: existence ends during namespace: uberon def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely." [https://orcid.org/0000-0002-6601-2165] def: "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "ceases_to_exist_during" EXACT [] xref: RO:0002492 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during_or_before ! existence ends during or before is_a: existence_overlaps ! existence overlaps transitive_over: part_of ! part_of [Typedef] id: existence_ends_during_or_before name: existence ends during or before namespace: uberon def: "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002497 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: developmentally_succeeded_by existence_ends_during_or_before holds_over_chain: part_of existence_ends_during_or_before is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage transitive_over: part_of ! part_of transitive_over: precedes ! precedes transitive_over: simultaneous_with ! simultaneous with [Typedef] id: existence_ends_with name: existence ends with namespace: uberon def: "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002493 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during ! existence ends during [Typedef] id: existence_overlaps name: existence overlaps def: "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002490 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage [Typedef] id: existence_starts_during name: existence starts during namespace: uberon def: "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." [] xref: RO:0002488 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_overlaps ! existence overlaps is_a: existence_starts_during_or_after ! existence starts during or after transitive_over: part_of ! part_of [Typedef] id: existence_starts_during_or_after name: existence starts during or after namespace: uberon def: "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002496 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: developmentally_preceded_by existence_starts_during_or_after holds_over_chain: part_of existence_starts_during_or_after is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage transitive_over: part_of ! part_of transitive_over: preceded_by ! preceded by transitive_over: simultaneous_with ! simultaneous with [Typedef] id: existence_starts_with name: existence starts with namespace: uberon def: "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y)." [] xref: RO:0002489 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_starts_during ! existence starts during [Typedef] id: function_of name: function of def: "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000079 property_value: IAO:0000112 "this catalysis function is a function of this enzyme" xsd:string property_value: IAO:0000116 "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists." xsd:string property_value: IAO:0000118 "function_of" xsd:string property_value: IAO:0000118 "is function of" xsd:string domain: BFO:0000034 ! function is_a: characteristic_of ! characteristic of inverse_of: has_function ! has function [Typedef] id: functionally_related_to name: functionally related to namespace: uberon def: "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." [] xref: RO:0002328 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This is a grouping relation that collects relations used for the purpose of connecting structure and function" xsd:string [Typedef] id: has_characteristic name: has characteristic def: "Inverse of characteristic_of" [] xref: RO:0000053 property_value: IAO:0000111 "bearer of" xsd:string property_value: IAO:0000112 "this apple is bearer of this red color" xsd:string property_value: IAO:0000112 "this vase is bearer of this fragility" xsd:string property_value: IAO:0000116 "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist." xsd:string property_value: IAO:0000118 "bearer_of" xsd:string property_value: IAO:0000118 "is bearer of" xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso https://github.com/oborel/obo-relations/pull/284 xsd:string range: BFO:0000020 ! characteristic is_inverse_functional: true [Typedef] id: has_component name: has component namespace: uberon def: "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] subset: ro-eco xref: RO:0002180 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." xsd:string property_value: IAO:0000232 "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit." xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:Componency is_a: has_part ! has part [Typedef] id: has_component_activity name: has component activity comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. xref: RO:0002017 is_a: has_component_process ! has component process created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-05-24T09:44:33Z [Typedef] id: has_component_process name: has component process def: "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] xref: RO:0002018 domain: BFO:0000015 ! process range: BFO:0000015 ! process is_a: has_component ! has component created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-05-24T09:49:21Z [Typedef] id: has_developmental_contribution_from name: has developmental contribution from namespace: uberon def: "x has developmental contribution from y iff x has some part z such that z develops from y" [] xref: RO:0002254 property_value: IAO:0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: UBERON:0001062 ! anatomical entity range: UBERON:0001062 ! anatomical entity holds_over_chain: has_part develops_from is_a: developmentally_preceded_by ! developmentally preceded by inverse_of: developmentally_contributes_to ! developmentally contributes to [Typedef] id: has_developmental_potential_involving name: has developmental potential involving def: "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." [] xref: RO:0002384 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: UBERON:0001062 ! anatomical entity range: UBERON:0001062 ! anatomical entity is_a: developmentally_related_to ! developmentally related to [Typedef] id: has_disposition name: has disposition def: "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence" [] xref: RO:0000091 domain: BFO:0000004 ! independent continuant range: BFO:0000016 ! disposition is_a: has_characteristic ! has characteristic inverse_of: disposition_of ! disposition of [Typedef] id: has_effector_activity name: has effector activity def: "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." [https://orcid.org/0000-0002-7073-9172] comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. xref: RO:0002025 is_functional: true is_a: has_component_activity ! has component activity created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-09-22T14:14:36Z [Typedef] id: has_function name: has function def: "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence" [] xref: RO:0000085 property_value: IAO:0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)" xsd:string property_value: IAO:0000116 "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists." xsd:string property_value: IAO:0000118 "has_function" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000034 ! function is_a: has_characteristic ! has characteristic [Typedef] id: has_input name: has input def: "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002233 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "consumes" xsd:string property_value: seeAlso https://wiki.geneontology.org/Has_input xsd:anyURI domain: BFO:0000015 ! process holds_over_chain: starts_with has_input is_a: has_participant ! has participant inverse_of: input_of ! input of [Typedef] id: has_negative_regulatory_component_activity name: has negative regulatory component activity def: "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. xref: RO:0002014 is_a: has_regulatory_component_activity ! has regulatory component activity is_a: negatively_regulated_by ! negatively regulated by created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-05-24T09:31:01Z [Typedef] id: has_part name: has part name: has_part namespace: quality namespace: spatial namespace: uberon def: "a core relation that holds between a whole and its part" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000051 property_value: IAO:0000111 "has part" xsd:string property_value: IAO:0000112 "my body has part my brain (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)" xsd:string property_value: IAO:0000112 "this year has part this day (occurrent parthood)" xsd:string property_value: IAO:0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part." xsd:string property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'." xsd:string property_value: IAO:0000118 "has_part" xsd:string property_value: RO:0001900 RO:0001901 is_transitive: true is_a: overlaps ! overlaps [Typedef] id: has_part_structure_that_is_capable_of name: has part structure that is capable of def: "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" [] xref: RO:0002584 property_value: IAO:0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: has_part capable_of is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process is_a: functionally_related_to ! functionally related to [Typedef] id: has_participant name: has participant def: "a relation between a process and a continuant, in which the continuant is somehow involved in the process" [] xref: RO:0000057 property_value: http://purl.org/dc/terms/source http://www.obofoundry.org/ro/#OBO_REL:has_participant xsd:string property_value: IAO:0000111 "has participant" xsd:string property_value: IAO:0000112 "this blood coagulation has participant this blood clot" xsd:string property_value: IAO:0000112 "this investigation has participant this investigator" xsd:string property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string property_value: IAO:0000116 "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." xsd:string property_value: IAO:0000118 "has_participant" xsd:string domain: BFO:0000003 ! occurrent domain: BFO:0000015 ! process range: BFO:0000002 ! continuant holds_over_chain: has_part has_participant [Typedef] id: has_positive_regulatory_component_activity name: has positive regulatory component activity def: "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. xref: RO:0002015 is_a: has_regulatory_component_activity ! has regulatory component activity is_a: positively_regulated_by ! positively regulated by created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-05-24T09:31:17Z [Typedef] id: has_potential_to_develop_into name: has potential to develop into namespace: uberon def: "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" [] xref: RO:0002387 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: has_potential_to_developmentally_contribute_to name: has potential to developmentally contribute to namespace: uberon def: "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" [] xref: RO:0002385 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: has_potential_to_directly_develop_into name: has potential to directly develop into def: "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" [] xref: RO:0002388 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_potential_to_develop_into ! has potential to develop into [Typedef] id: has_quality name: has quality namespace: uberon def: "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence" [] xref: RO:0000086 property_value: IAO:0000112 "this apple has quality this red color" xsd:string property_value: IAO:0000116 "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist." xsd:string property_value: IAO:0000118 "has_quality" xsd:string range: BFO:0000019 ! quality is_a: has_characteristic ! has characteristic [Typedef] id: has_regulatory_component_activity name: has regulatory component activity def: "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." [] xref: RO:0002013 is_a: has_component_activity ! has component activity is_a: regulated_by ! regulated by created_by: https://orcid.org/0000-0002-7073-9172 creation_date: 2017-05-24T09:30:46Z [Typedef] id: has_role name: has role def: "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence" [] xref: RO:0000087 property_value: IAO:0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)" xsd:string property_value: IAO:0000116 "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists." xsd:string property_value: IAO:0000118 "has_role" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000023 ! role is_a: has_characteristic ! has characteristic [Typedef] id: helper_property_(not_for_use_in_curation) name: helper property (not for use in curation) xref: RO:0002464 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." xsd:string [Typedef] id: immediately_causally_downstream_of name: immediately causally downstream of xref: RO:0002405 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: causally_downstream_of ! causally downstream of is_a: immediately_preceded_by ! immediately preceded by inverse_of: immediately_causally_upstream_of ! immediately causally upstream of [Typedef] id: immediately_causally_upstream_of name: immediately causally upstream of def: "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." [] xref: RO:0002412 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0002575 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: immediately_precedes ! immediately precedes [Typedef] id: immediately_preceded_by name: immediately preceded by namespace: uberon comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) xref: RO:0002087 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "starts_at_end_of" xsd:string holds_over_chain: starts_with ends_with is_a: preceded_by ! preceded by inverse_of: immediately_precedes ! immediately precedes [Typedef] id: immediately_precedes name: immediately precedes comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) subset: ro-eco xref: RO:0002090 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "ends_at_start_of" xsd:string property_value: IAO:0000118 "meets" xsd:string property_value: RO:0002575 BFO:0000063 holds_over_chain: ends_with starts_with is_a: precedes ! precedes [Typedef] id: in_lateral_side_of name: in lateral side of namespace: spatial namespace: uberon def: "X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure" [UBERON:cjm] xref: BSPO:0000126 property_value: seeAlso https://github.com/obophenotype/uberon/issues/2453 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI is_a: part_of ! part_of [Typedef] id: in_left_side_of name: in left side of namespace: spatial namespace: uberon def: "X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000120 xref: NCIT:C25229 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI is_a: in_lateral_side_of ! in lateral side of disjoint_from: in_right_side_of ! in right side of [Typedef] id: in_right_side_of name: in right side of namespace: spatial namespace: uberon def: "X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000121 xref: NCIT:C25228 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern xsd:anyURI is_a: in_lateral_side_of ! in lateral side of [Typedef] id: in_taxon name: in taxon namespace: uberon def: "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." [] comment: Connects a biological entity to its taxon of origin. subset: ro-eco xref: RO:0002162 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9227-417X property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints holds_over_chain: capable_of in_taxon holds_over_chain: develops_from in_taxon holds_over_chain: existence_ends_during in_taxon holds_over_chain: existence_starts_during in_taxon holds_over_chain: has_developmental_contribution_from in_taxon holds_over_chain: has_part in_taxon holds_over_chain: has_potential_to_develop_into in_taxon holds_over_chain: overlaps in_taxon holds_over_chain: part_of in_taxon holds_over_chain: results_in_developmental_progression_of in_taxon is_a: evolutionarily_related_to ! evolutionarily related to [Typedef] id: indirectly_causally_upstream_of name: indirectly causally upstream of def: "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." [] xref: RO:0012011 is_a: causally_upstream_of ! causally upstream of created_by: https://orcid.org/0000-0003-1813-6857 creation_date: 2022-09-26T06:07:17Z [Typedef] id: indirectly_negatively_regulates name: indirectly negatively regulates def: "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." [] xref: RO:0002409 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly inhibits" xsd:string property_value: RO:0002579 RO:0002212 property_value: seeAlso https://wiki.geneontology.org/Indirectly_negatively_regulates xsd:anyURI holds_over_chain: directly_negatively_regulates directly_negatively_regulates holds_over_chain: directly_negatively_regulates indirectly_negatively_regulates is_transitive: true is_a: indirectly_regulates ! indirectly regulates is_a: negatively_regulates ! negatively regulates transitive_over: directly_negatively_regulates ! directly negatively regulates [Typedef] id: indirectly_positively_regulates name: indirectly positively regulates def: "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." [] xref: RO:0002407 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly activates" xsd:string property_value: RO:0002579 RO:0002213 property_value: seeAlso https://wiki.geneontology.org/Indirectly_positively_regulates xsd:anyURI holds_over_chain: directly_positively_regulates directly_positively_regulates holds_over_chain: directly_positively_regulates indirectly_positively_regulates holds_over_chain: indirectly_negatively_regulates indirectly_negatively_regulates is_transitive: true is_a: indirectly_regulates ! indirectly regulates is_a: positively_regulates ! positively regulates transitive_over: directly_positively_regulates ! directly positively regulates [Typedef] id: indirectly_regulates name: indirectly regulates def: "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." [] xref: RO:0012012 is_a: indirectly_causally_upstream_of ! indirectly causally upstream of is_a: regulates ! regulates created_by: https://orcid.org/0000-0003-1813-6857 creation_date: 2022-09-26T06:08:01Z [Typedef] id: input_of name: input of namespace: uberon def: "inverse of has input" [] subset: ro-eco subset: RO:0002259 xref: RO:0002352 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: functionally_related_to ! functionally related to is_a: participates_in ! participates in [Typedef] id: interaction_relation_helper_property name: interaction relation helper property xref: RO:0002563 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29 property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ xsd:anyURI is_a: helper_property_(not_for_use_in_curation) ! helper property (not for use in curation) [Typedef] id: interacts_with name: interacts with def: "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." [] subset: ro-eco synonym: "in pairwise interaction with" EXACT [] xref: RO:0002434 property_value: closeMatch http://purl.obolibrary.org/obo/MI_0914 xsd:anyURI property_value: IAO:0000116 "Considering relabeling as 'pairwise interacts with'" xsd:anyURI property_value: IAO:0000116 "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." xsd:string property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/interaction-relations/ xsd:anyURI domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_symmetric: true [Typedef] id: involved_in name: involved in def: "c involved_in p if and only if c enables some process p', and p' is part of p" [] xref: RO:0002331 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "actively involved in" xsd:string property_value: IAO:0000118 "enables part of" xsd:string property_value: seeAlso https://wiki.geneontology.org/Involved_in xsd:anyURI holds_over_chain: enables part_of is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of is_a: participates_in ! participates in transitive_over: part_of ! part_of [Typedef] id: involved_in_negative_regulation_of name: involved in negative regulation of def: "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" [] xref: RO:0002430 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0004050 RO:0002428 holds_over_chain: enables negatively_regulates holds_over_chain: involved_in negatively_regulates is_a: involved_in_regulation_of ! involved in regulation of [Typedef] id: involved_in_or_involved_in_regulation_of name: involved in or involved in regulation of def: "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" [] xref: RO:0002431 property_value: IAO:0000116 "OWL does not allow defining object properties via a Union" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "involved in or reguates" xsd:string is_a: acts_upstream_of_or_within ! acts upstream of or within is_a: causal_agent_in_process ! causal agent in process is_a: functionally_related_to ! functionally related to [Typedef] id: involved_in_positive_regulation_of name: involved in positive regulation of def: "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" [] xref: RO:0002429 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0004049 RO:0002428 holds_over_chain: enables positively_regulates holds_over_chain: involved_in positively_regulates is_a: involved_in_regulation_of ! involved in regulation of [Typedef] id: involved_in_regulation_of name: involved in regulation of def: "c involved in regulation of p if c is involved in some p' and p' regulates some p" [] xref: RO:0002428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: enables regulates holds_over_chain: involved_in regulates is_a: acts_upstream_of ! acts upstream of is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of [Typedef] id: is_kinase_activity name: is kinase activity xref: RO:0002481 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: molecular_interaction_relation_helper_property ! molecular interaction relation helper property [Typedef] id: mereotopologically_related_to name: mereotopologically related to def: "A mereological relationship or a topological relationship" [] xref: RO:0002323 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" xsd:string property_value: RO:0001900 RO:0001901 [Typedef] id: molecular_interaction_relation_helper_property name: molecular interaction relation helper property xref: RO:0002564 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: interaction_relation_helper_property ! interaction relation helper property [Typedef] id: molecularly_interacts_with name: molecularly interacts with def: "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." [] xref: RO:0002436 property_value: closeMatch http://purl.obolibrary.org/obo/MI_0915 xsd:anyURI property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "binds" xsd:string property_value: IAO:0000118 "molecularly binds with" xsd:string property_value: seeAlso ECO:0000353 is_symmetric: true is_a: interacts_with ! interacts with [Typedef] id: negatively_regulated_by name: negatively regulated by def: "inverse of negatively regulates" [] subset: RO:0002259 xref: RO:0002335 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: regulated_by ! regulated by [Typedef] id: negatively_regulates name: negatively regulates def: "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002212 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002211 holds_over_chain: ends_with negatively_regulates is_a: causally_upstream_of,_negative_effect ! causally upstream of, negative effect is_a: regulates ! regulates inverse_of: negatively_regulated_by ! negatively regulated by [Typedef] id: negatively_regulates_characteristic name: negatively regulates characteristic def: "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." [] xref: RO:0019002 property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599 holds_over_chain: negatively_regulates positively_regulates_characteristic holds_over_chain: positively_regulates negatively_regulates_characteristic is_a: regulates_characteristic ! regulates characteristic [Typedef] id: only_in_taxon name: only in taxon namespace: uberon def: "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z." [] xref: RO:0002160 property_value: IAO:0000112 "lactation SubClassOf 'only in taxon' some 'Mammalia'" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.\n\n 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints is_a: in_taxon ! in taxon [Typedef] id: overlaps name: overlaps namespace: spatial namespace: uberon def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" [] def: "x overlaps y iff they have some part in common." [BSPO:cjm] comment: "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002131 property_value: IAO:0000114 IAO:0000125 property_value: RO:0001900 RO:0001901 holds_over_chain: has_part overlaps holds_over_chain: has_part part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} holds_over_chain: part_of part_of is_symmetric: true is_a: mereotopologically_related_to ! mereotopologically related to transitive_over: part_of ! part_of expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" [] [Typedef] id: part_of name: part of name: part_of namespace: quality namespace: spatial namespace: uberon def: "a core relation that holds between a part and its whole" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000050 property_value: IAO:0000111 "is part of" xsd:string property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string property_value: IAO:0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string property_value: IAO:0000116 "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: IAO:0000116 "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string property_value: IAO:0000118 "part_of" xsd:string property_value: RO:0001900 RO:0001901 property_value: RO:0040042 BFO:0000002 property_value: RO:0040042 BFO:0000003 property_value: RO:0040042 BFO:0000004 property_value: RO:0040042 BFO:0000017 property_value: RO:0040042 BFO:0000019 property_value: RO:0040042 BFO:0000020 property_value: RO:0040042 BFO:0000031 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf property_value: seeAlso http://www.obofoundry.org/ro/#OBO_REL:part_of xsd:string property_value: seeAlso https://wiki.geneontology.org/Part_of xsd:anyURI is_transitive: true is_a: overlaps ! overlaps inverse_of: has_part ! has part [Typedef] id: part_of_structure_that_is_capable_of name: part of structure that is capable of def: "this relation holds between c and p when c is part of some c', and c' is capable of p." [] xref: RO:0002329 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "false" xsd:boolean holds_over_chain: part_of capable_of {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: functionally_related_to ! functionally related to [Typedef] id: participates_in name: participates in namespace: uberon def: "a relation between a continuant and a process, in which the continuant is somehow involved in the process" [] xref: RO:0000056 property_value: IAO:0000111 "participates in" xsd:string property_value: IAO:0000112 "this blood clot participates in this blood coagulation" xsd:string property_value: IAO:0000112 "this input material (or this output material) participates in this process" xsd:string property_value: IAO:0000112 "this investigator participates in this investigation" xsd:string property_value: IAO:0000118 "participates_in" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000003 ! occurrent inverse_of: has_participant ! has participant [Typedef] id: phosphorylates name: phosphorylates xref: RO:0002447 property_value: IAO:0000116 "Axiomatization to GO to be added later" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." xsd:string is_a: molecularly_interacts_with ! molecularly interacts with [Typedef] id: positively_regulated_by name: positively regulated by def: "inverse of positively regulates" [] subset: RO:0002259 xref: RO:0002336 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: regulated_by ! regulated by [Typedef] id: positively_regulates name: positively regulates def: "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002213 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002211 holds_over_chain: ends_with positively_regulates holds_over_chain: negatively_regulates negatively_regulates is_transitive: true is_a: causally_upstream_of,_positive_effect ! causally upstream of, positive effect is_a: regulates ! regulates inverse_of: positively_regulated_by ! positively regulated by [Typedef] id: positively_regulates_characteristic name: positively regulates characteristic def: "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." [] xref: RO:0019001 property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599 holds_over_chain: positively_regulates positively_regulates_characteristic is_a: regulates_characteristic ! regulates characteristic [Typedef] id: preceded_by name: preceded by namespace: uberon def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: BFO:0000062 property_value: http://purl.org/dc/terms/source http://www.obofoundry.org/ro/#OBO_REL:preceded_by xsd:string property_value: IAO:0000111 "preceded by" xsd:string property_value: IAO:0000116 "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." xsd:string property_value: IAO:0000118 "is preceded by" xsd:string property_value: IAO:0000118 "preceded_by" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of preceded_by is_transitive: true is_a: ends_after ! ends after inverse_of: precedes ! precedes [Typedef] id: precedes name: precedes namespace: uberon def: "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: BFO:0000063 property_value: IAO:0000111 "precedes" xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of precedes is_transitive: true is_a: temporally_related_to ! temporally related to [Typedef] id: process_has_causal_agent name: process has causal agent def: "Inverse of 'causal agent in process'" [] xref: RO:0002608 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations is_a: causally_related_to ! causally related to [Typedef] id: quality_of name: quality of def: "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000080 property_value: IAO:0000112 "this red color is a quality of this apple" xsd:string property_value: IAO:0000116 "A quality inheres in its bearer at all times for which the quality exists." xsd:string property_value: IAO:0000118 "is quality of" xsd:string property_value: IAO:0000118 "quality_of" xsd:string is_a: characteristic_of ! characteristic of inverse_of: has_quality ! has quality [Typedef] id: regulated_by name: regulated by def: "inverse of regulates" [] subset: RO:0002259 xref: RO:0002334 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000589 "regulated by (processual)" xsd:string domain: BFO:0000015 ! process range: BFO:0000015 ! process is_transitive: true is_a: causally_downstream_of_or_within ! causally downstream of or within [Typedef] id: regulates name: regulates name: regulates (processual) def: "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002211 property_value: IAO:0000117 https://orcid.org/0000-0001-7476-6306 property_value: IAO:0000117 https://orcid.org/0000-0002-3837-8864 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GO" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Regulation precludes parthood; the regulatory process may not be within the regulated process." xsd:string property_value: IAO:0000589 "regulates (processual)" xsd:string property_value: IAO:0000600 "false" xsd:boolean domain: BFO:0000015 ! process range: BFO:0000015 ! process holds_over_chain: directly_regulates directly_regulates holds_over_chain: ends_with regulates is_transitive: true is_a: causally_upstream_of ! causally upstream of inverse_of: regulated_by ! regulated by transitive_over: has_effector_activity ! has effector activity [Typedef] id: regulates_activity_of name: regulates activity of def: "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." [] xref: RO:0011002 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: causally_influences ! causally influences [Typedef] id: regulates_characteristic name: regulates characteristic def: "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." [] xref: RO:0019000 property_value: http://purl.org/dc/terms/contributor https://orcid.org/0000-0002-8688-6599 domain: BFO:0000015 ! process range: PATO:0000001 ! quality holds_over_chain: regulates regulates_characteristic is_a: causally_related_to ! causally related to [Typedef] id: relation_between_physical_entity_and_a_process_or_stage name: relation between physical entity and a process or stage xref: RO:0002487 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000003 ! occurrent [Typedef] id: results_in_acquisition_of_features_of name: results in acquisition of features of def: "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002315 property_value: IAO:0000112 "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 GOC:mtg_berkeley_2013 xsd:string range: UBERON:0000061 ! anatomical structure is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_changes_to_anatomical_or_cellular_structure name: results in changes to anatomical or cellular structure def: "p has anatomical participant c iff p has participant c, and c is an anatomical entity" [] xref: RO:0040036 is_a: has_participant ! has participant created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-09-26T01:08:58Z [Typedef] id: results_in_development_of name: results in development of def: "p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002296 property_value: IAO:0000112 "every flower development (GO:0009908) results in development of some flower (PO:0009046)" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.geneontology.org/GO.doc.development.shtml xsd:anyURI is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_developmental_progression_of name: results in developmental progression of def: "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." [] xref: RO:0002295 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000116 "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso Ontology:extensions domain: GO:0008150 ! biological process range: UBERON:0001062 ! anatomical entity is_a: developmentally_related_to ! developmentally related to [Typedef] id: role_of name: role of def: "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000081 property_value: IAO:0000112 "this investigator role is a role of this person" xsd:string property_value: IAO:0000116 "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists." xsd:string property_value: IAO:0000118 "is role of" xsd:string property_value: IAO:0000118 "role_of" xsd:string is_a: characteristic_of ! characteristic of inverse_of: has_role ! has role [Typedef] id: simultaneous_with name: simultaneous with namespace: uberon def: "x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time." [] comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) subset: ro-eco xref: RO:0002082 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 is_symmetric: true is_transitive: true is_a: before_or_simultaneous_with ! before or simultaneous with [Typedef] id: starts name: starts namespace: uberon def: "inverse of starts with" [] subset: ro-eco xref: RO:0002223 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Allen" xsd:string is_a: part_of ! part_of is_a: temporally_related_to ! temporally related to inverse_of: starts_with ! starts with [Typedef] id: starts_with name: starts with namespace: uberon def: "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: RO:0002224 property_value: IAO:0000112 "Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "started by" xsd:string is_transitive: true is_a: has_part ! has part is_a: temporally_related_to ! temporally related to [Typedef] id: temporally_related_to name: temporally related to comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. subset: ro-eco xref: RO:0002222 property_value: http://purl.org/dc/terms/source https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1 xsd:anyURI property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 https://en.wikipedia.org/wiki/Allen%27s_interval_algebra property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." xsd:string domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent