http://dx.doi.org/10.1186/2041-1480-4-30
http://orcid.org/0000-0002-1373-1705
http://orcid.org/0000-0002-7073-9172
https://orcid.org/0000-0001-5948-3092
https://orcid.org/0000-0002-0027-0858
A miscellaneous ontology of terms used for curation in FlyBase, including the DPO.
FlyBase Controlled Vocabulary (FBcv)
https://creativecommons.org/licenses/by/3.0/
12:06:2020 09:53
FlyBase miscellaneous CV
1.2
editor preferred term
example of usage
has curation status
definition
editor note
term editor
alternative term
definition source
curator note
imported from
expand expression to
OBO foundry unique label
elucidation
term replaced by
An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.
temporal interpretation
https://github.com/oborel/obo-relations/wiki/ROAndTime
defined by inverse
logical macro assertion on an annotation property
relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y
The general property hierarchy is:
"directly P" SubPropertyOf "P"
Transitive(P)
Where we have an annotation assertion
"directly P" "is direct form of" "P"
If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'
Chris Mungall
is direct form of
If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL
is a defining property chain axiom
If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.
is a defining property chain axiom where second argument is reflexive
cjm
2018-03-14T00:03:16Z
is positive form of
cjm
2018-03-14T00:03:24Z
is negative form of
part-of is homeomorphic for independent continuants.
R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C.
cjm
2018-10-21T19:46:34Z
R homeomorphic-for C expands to: C SubClassOf R only C. Additionally, for any class D that is disjoint with C, we can also expand to C DisjointWith R some D, D DisjointWith R some C.
is homeomorphic for
BRAND NAME
INN
IUPAC NAME
Preliminary entries
Annotated by 3rd party
Manually annotated by ChEBI Team
BrainName official abbreviation
BRAND NAME
EmbDevSlim
FORMULA
FlyTed temp subset for edit tracking purposes
Testis slim
INN
IUPAC NAME
InChI
InChIKey
terms for rd test ontology
SMILES
Abnormal/normal slim
Absent/present slim
Attribute slim
camcur
cell_quality
Terms to summarize typical use of a gene from one organism that is introduced into another organism primarily for use an experimental tool, rather than to study the function of the gene
cur
warning of impending obsoletion
Term not to be used for direct annotation
do not annotate
Term not to be used for direct manual annotation
MGI ribbon terms
fbcvsubset_mgiribbons
larval olfactory system
lethal phase terms
Relational slim: types of quality that require an additional entity in order to exist
Systematic synonym
Value slim
eco subset
subset_property
synonym_type_property
consider
has_alternative_id
has_broad_synonym
database_cross_reference
has_exact_synonym
has_narrow_synonym
has_obo_format_version
has_obo_namespace
has_related_synonym
has_scope
has_synonym_type
in_subset
shorthand
is part of
my brain is part of my body (continuant parthood, two material entities)
my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
this day is part of this year (occurrent parthood)
a core relation that holds between a part and its whole
Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)
A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
part_of
BFO:0000050
OBO_REL:part_of
part_of
external
protein
quality
relationship
uberon
part_of
part_of
part of
part of
part_of
http://www.obofoundry.org/ro/#OBO_REL:part_of
has part
my body has part my brain (continuant parthood, two material entities)
my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
this year has part this day (occurrent parthood)
Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2.
a core relation that holds between a whole and its part
Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime
Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)
A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
has_part
BFO:0000051
OBO_REL:has_part
chebi_ontology
external
protein
quality
relationship
uberon
has_part
false
has_part
We use the has_part relation to relate complex qualities to more primitive ones. A complex quality is a collection of qualities. The complex quality cannot exist without the sub-qualities. For example, the quality 'swollen' necessarily comes with the qualities of 'protruding' and 'increased size'.
has part
has part
has_part
Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2.
PATOC:CJM
preceded by
X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)
x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
is preceded by
preceded_by
http://www.obofoundry.org/ro/#OBO_REL:preceded_by
djs93
2009-10-09T10:00:53Z
BFO:0000062
OBO_REL:preceded_by
is preceded by
takes place after
relationship
uberon
preceded_by
preceded_by
preceded by
preceded_by
is preceded by
SIO:000249
takes place after
Allen:precedes
precedes
x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
BFO:0000063
uberon
precedes
precedes
precedes
precedes
occurs in
b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
occurs_in
unfolds in
unfolds_in
Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant
occurs in
site of
[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant
contains process
has_age
FBdv:00018001
relationship
substage_of
substage_of
Creating this relation as a temporary fix, pending adding the axiom occurent_part_of subpropertyof happens_during to RO
substage_of
inheres in
this fragility inheres in this vase
this red color inheres in this apple
a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence
A dependent inheres in its bearer at all times for which the dependent exists.
inheres_in
RO:0000052
fly_anatomy.ontology
inheres_in
inheres_in
inheres in
inheres_in
bearer of
this apple is bearer of this red color
this vase is bearer of this fragility
a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence
A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
bearer_of
is bearer of
bearer of
participates in
this blood clot participates in this blood coagulation
this input material (or this output material) participates in this process
this investigator participates in this investigation
a relation between a continuant and a process, in which the continuant is somehow involved in the process
participates_in
participates in
has participant
this blood coagulation has participant this blood clot
this investigation has participant this investigator
this process has participant this input material (or this output material)
a relation between a process and a continuant, in which the continuant is somehow involved in the process
Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
has_participant
http://www.obofoundry.org/ro/#OBO_REL:has_participant
has participant
this investigator role is a role of this person
a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
is role of
role_of
role of
this person has role this investigator role (more colloquially: this person has this role of investigator)
a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
has_role
RO:0000087
FlyBase miscellaneous CV
chebi_ontology
has_role
false
false
has_role
has role
has role
A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
dos
2017-05-24T09:30:46Z
has regulatory component activity
A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
dos
2017-05-24T09:31:01Z
By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.
has negative regulatory component activity
A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
dos
2017-05-24T09:31:17Z
By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.
has positive regulatory component activity
dos
2017-05-24T09:44:33Z
A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.
has component activity
w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
dos
2017-05-24T09:49:21Z
has component process
A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.
dos
2017-07-19T17:30:36Z
has ligand
dos
2017-09-17T13:52:24Z
Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
directly regulated by
Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
GOC:dos
Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
dos
2017-09-17T13:52:38Z
directly negatively regulated by
Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
GOC:dos
Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
dos
2017-09-17T13:52:47Z
directly positively regulated by
Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
GOC:dos
A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
dos
2017-09-22T14:14:36Z
This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.
has effector activity
A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.
GOC:dos
David Osumi-Sutherland
X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)
ends after
David Osumi-Sutherland
starts_at_end_of
X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)
immediately preceded by
David Osumi-Sutherland
ends_at_start_of
meets
X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)
immediately precedes
x overlaps y if and only if there exists some z such that x has part z and z part of y
http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
overlaps
true
w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.
For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.
has component
x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
Chris Mungall
David Osumi-Sutherland
Melissa Haendel
Terry Meehan
This is the transitive form of the develops from relation
develops from
inverse of develops from
Chris Mungall
David Osumi-Sutherland
Terry Meehan
develops into
process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.
We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit
Chris Mungall
David Hill
Tanya Berardini
GO
Regulation precludes parthood; the regulatory process may not be within the regulated process.
regulates (processual)
false
regulates
Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
Chris Mungall
negatively regulates (process to process)
negatively regulates
Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
Chris Mungall
positively regulates (process to process)
positively regulates
mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
osteoclast SubClassOf 'capable of' some 'bone resorption'
A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
Chris Mungall
has function realized in
For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
RO_0000053 some (RO_0000054 only ?Y)
capable of
c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
Chris Mungall
has function in
RO_0000053 some (RO_0000054 only (BFO_0000050 some ?Y))
capable of part of
true
OBSOLETE x actively participates in y if and only if x participates in y and x realizes some active role
Chris Mungall
agent in
Obsoleted as the inverse property was obsoleted.
obsolete actively participates in
true
'heart development' has active participant some Shh protein
x has participant y if and only if x realizes some active role that inheres in y
This may be obsoleted and replaced by the original 'has agent' relation
Chris Mungall
has agent
obsolete has active participant
true
Chris Mungall
Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1
A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.
temporally related to
p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
Chris Mungall
consumes
has input
Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
x has developmental contribution from y iff x has some part z such that z develops from y
Chris Mungall
has developmental contribution from
inverse of has developmental contribution from
Chris Mungall
developmentally contributes to
Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
false
Chris Mungall
In general you should not use this relation to make assertions - use one of the more specific relations below this one
This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from
developmentally preceded by
A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision.
c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
acts upstream of
A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway.
c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
affects
acts upstream of or within
Inverse of developmentally preceded by
Chris Mungall
developmentally succeeded by
cjm
holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y
causally upstream of, positive effect
cjm
holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y
causally upstream of, negative effect
q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.
Because part_of is transitive, inheres in is a sub-relation of inheres in part of
Chris Mungall
inheres in part of
true
A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions
ecologically related to
A mereological relationship or a topological relationship
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
mereotopologically related to
A relationship that holds between entities participating in some developmental process (GO:0032502)
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development
developmentally related to
a particular instances of akt-2 enables some instance of protein kinase activity
Chris Mungall
catalyzes
executes
has
is catalyzing
is executing
This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.
This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time.
enables
A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
Chris Mungall
This is a grouping relation that collects relations used for the purpose of connecting structure and function
functionally related to
this relation holds between c and p when c is part of some c', and c' is capable of p.
Chris Mungall
false
part of structure that is capable of
true
c involved_in p if and only if c enables some process p', and p' is part of p
Chris Mungall
actively involved in
enables part of
involved in
inverse of enables
Chris Mungall
enabled by
inverse of regulates
Chris Mungall
regulated by (processual)
regulated by
inverse of negatively regulates
Chris Mungall
negatively regulated by
inverse of positively regulates
Chris Mungall
positively regulated by
An organism that is a member of a population of organisms
is member of is a mereological relation between a item and a collection.
is member of
member part of
SIO
member of
has member is a mereological relation between a collection and an item.
SIO
RO:0002351
uberon
has_member
has_member
has member
has member
inverse of has input
Chris Mungall
input of
A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.
Chris Mungall
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships
This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)
in branching relationship with
https://github.com/obophenotype/uberon/issues/170
x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
Chris Mungall
has developmental potential involving
x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
Chris Mungall
has potential to developmentally contribute to
x has the potential to develop into y iff x develops into y or if x is capable of developing into y
Chris Mungall
has potential to develop into
x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
Chris Mungall
has potential to directly develop into
inverse of upstream of
Chris Mungall
causally downstream of
Chris Mungall
immediately causally downstream of
This relation groups causal relations between material entities and causal relations between processes
This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.
To define causal relations in an activity-flow type network, we make use of 3 primitives:
* Temporal: how do the intervals of the two occurrents relate?
* Is the causal relation regulatory?
* Is the influence positive or negative
The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.
For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.
For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.
Each of these 3 primitives can be composed to yield a cross-product of different relation types.
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causally related to
p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain
Chris Mungall
causally upstream of
p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.
Chris Mungall
immediately causally upstream of
transitive form of directly_provides_input_for
Chris Mungall
This is a grouping relation that should probably not be used in annotation. Consider instead the child relation 'directly provides input for' (which may later be relabeled simply to 'provides input for')
transitively provides input for (process to process)
transitively provides input for
p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.
We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
Chris Mungall
influences (processual)
affects
causally upstream of or within
inverse of causally upstream of or within
Chris Mungall
causally downstream of or within
c involved in regulation of p if c is involved in some p' and p' regulates some p
Chris Mungall
involved in regulation of
c involved in regulation of p if c is involved in some p' and p' positively regulates some p
Chris Mungall
involved in positive regulation of
c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
Chris Mungall
involved in negative regulation of
c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
OWL does not allow defining object properties via a Union
Chris Mungall
involved in or reguates
involved in or involved in regulation of
A protein that enables activity in a cytosol.
c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
Chris Mungall
executes activity in
enables activity in
is active in
true
c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
GOC:cjm
GOC:dos
A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
Considering relabeling as 'pairwise interacts with'
This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.
Chris Mungall
Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.
in pairwise interaction with
interacts with
http://purl.obolibrary.org/obo/MI_0914
https://github.com/oborel/obo-relations/wiki/InteractionRelations
An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
Chris Mungall
binds
molecularly binds with
molecularly interacts with
http://purl.obolibrary.org/obo/MI_0915
Axiomatization to GO to be added later
Chris Mungall
An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.
phosphorylates
The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
Chris Mungall
Vasundra Touré
molecularly controls
directly regulates activity of
The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
Chris Mungall
Vasundra Touré
directly inhibits
molecularly decreases activity of
directly negatively regulates activity of
The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
Chris Mungall
Vasundra Touré
directly activates
molecularly increases activity of
directly positively regulates activity of
Chris Mungall
This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.
helper property (not for use in curation)
p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
Chris Mungall
has part that occurs in
true
Chris Mungall
is kinase activity
A relationship between a material entity and a process where the material entity has some causal role that influences the process
causal agent in process
p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causal relation between processes
Chris Mungall
depends on
q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2
This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.
Chris Mungall
towards
The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch
Chris Mungall
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
causal relation between entities
s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.
Chris Mungall
determined by part of
A relation that holds between two entities that have the property of being sequences or having sequences.
Chris Mungall
http://www.ncbi.nlm.nih.gov/pubmed/20226267
Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving cause and effect.
The domain and range of this relation include entities such as: information-bearing macromolecules such as DNA, or regions of these molecules; abstract information entities encoded as a linear sequence including text, abstract DNA sequences; Sequence features, entities that have a sequence or sequences. Note that these entities are not necessarily contiguous - for example, the mereological sum of exons on a genome of a particular gene.
sequentially related to
The genomic exons of a transcript bound the sequence of the genomic introns of the same transcript (but the introns are not subsequences of the exons)
x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y
Chris Mungall
bounds sequence of
inverse of bounds sequence of
Chris Mungall
is bound by sequence of
x has subsequence y iff all of the sequence parts of x are sequence parts of y
Chris Mungall
contains
http://www.ncbi.nlm.nih.gov/pubmed/20226267
has subsequence
inverse of has subsequence
Chris Mungall
contained by
is subsequence of
x overlaps the sequence of x if and only if x has a subsequence z and z is a subsequence of y.
Chris Mungall
overlaps sequence of
Chris Mungall
causally influenced by (entity-centric)
causally influenced by
Chris Mungall
interaction relation helper property
https://github.com/oborel/obo-relations/wiki/InteractionRelations
Chris Mungall
molecular interaction relation helper property
The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
Chris Mungall
Vasundra Touré
causally influences (entity-centric)
causally influences
A relation that holds between an attribute or a qualifier and another attribute.
Chris Mungall
This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the "modifiers" are.
has modifier
Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
Chris Mungall
directly regulates (processual)
directly regulates
gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
Chris Mungall
has part structure that is capable of
A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
Chris Mungall
causal relation between material entity and a process
pyrethroid -> growth
Holds between c and p if and only if c is capable of some activity a, and a regulates p.
capable of regulating
Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
capable of negatively regulating
renin -> arteriolar smooth muscle contraction
Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
capable of positively regulating
Inverse of 'causal agent in process'
process has causal agent
Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.
directly positively regulates (process to process)
directly positively regulates
Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.
directly negatively regulates (process to process)
directly negatively regulates
p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.
cjm
2018-12-13T11:26:17Z
has primary input or output
Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
cjm
2018-01-25T23:20:13Z
enables subfunction
cjm
2018-01-26T23:49:30Z
acts upstream of or within, positive effect
cjm
2018-01-26T23:49:51Z
acts upstream of or within, negative effect
c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
cjm
2018-01-26T23:53:14Z
acts upstream of, positive effect
c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
cjm
2018-01-26T23:53:22Z
acts upstream of, negative effect
cjm
2018-03-13T23:55:05Z
causally upstream of or within, negative effect
cjm
2018-03-13T23:55:19Z
causally upstream of or within, positive effect
The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
Vasundra Touré
regulates activity of
chebi_ontology
has_functional_parent
false
false
has functional parent
chebi_ontology
has_parent_hydride
false
false
has parent hydride
chebi_ontology
is_conjugate_acid_of
true
false
is conjugate acid of
chebi_ontology
is_conjugate_base_of
true
false
is conjugate base of
chebi_ontology
is_enantiomer_of
true
false
is enantiomer of
chebi_ontology
is_substituent_group_from
false
false
is substituent group from
chebi_ontology
is_tautomer_of
true
is tautomer of
FlyBase miscellaneous CV
conditionality
conditionality
has_role
has role
An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
continuant
An entity that has temporal parts and that happens, unfolds or develops through time.
occurrent
A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
independent continuant
An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
process
A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
realizable entity
quality
A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
specifically dependent continuant
A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
role
A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
generically dependent continuant
An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
material entity
anatomical entity
biological entity
A naphthol carrying a hydroxy group at position 2.
0
C10H8O
InChI=1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H
JWAZRIHNYRIHIV-UHFFFAOYSA-N
144.16992
144.05751
Oc1ccc2ccccc2c1
Beilstein:742134
CAS:135-19-3
Drug_Central:3370
Gmelin:27395
HMDB:HMDB0012322
KEGG:C11713
PMID:14751800
PMID:18515997
PMID:22740618
Reaxys:742134
Wikipedia:2-Naphthol
2-Naphthol
naphthalen-2-ol
chebi_ontology
2-hydroxynaphthalene
2-naphthalenol
beta-Naphthol
beta-hydroxynaphthalene
beta-naphthol
CHEBI:10432
2-naphthol
Beilstein:742134
Beilstein
CAS:135-19-3
ChemIDplus
CAS:135-19-3
KEGG COMPOUND
CAS:135-19-3
NIST Chemistry WebBook
Drug_Central:3370
DrugCentral
Gmelin:27395
Gmelin
PMID:14751800
Europe PMC
PMID:18515997
Europe PMC
PMID:22740618
Europe PMC
Reaxys:742134
Reaxys
2-Naphthol
KEGG_COMPOUND
naphthalen-2-ol
IUPAC
2-hydroxynaphthalene
HMDB
2-naphthalenol
NIST_Chemistry_WebBook
beta-Naphthol
KEGG_COMPOUND
beta-hydroxynaphthalene
NIST_Chemistry_WebBook
beta-naphthol
NIST_Chemistry_WebBook
Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
-1
0.000548579903
0.0
KEGG:C05359
PMID:21614077
Wikipedia:Electron
electron
chebi_ontology
Elektron
beta
beta(-)
beta-particle
e
e(-)
e-
negatron
CHEBI:10545
electron
PMID:21614077
Europe PMC
electron
ChEBI
electron
IUPAC
electron
KEGG_COMPOUND
Elektron
ChEBI
beta
IUPAC
beta(-)
ChEBI
beta-particle
IUPAC
e
IUPAC
e(-)
UniProt
e-
KEGG_COMPOUND
negatron
IUPAC
A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.
chebi_ontology
dicarboxylic acids and derivatives
CHEBI:131927
dicarboxylic acids and O-substituted derivatives
dicarboxylic acids and derivatives
ChEBI
Any member of the class of benzoquinones that is 1,4-benzoquinone or its C-substituted derivatives.
0
C6O2R4
104.063
103.98983
O=C1C(*)=C(*)C(=O)C(*)=C1*
chebi_ontology
a quinone
p-benzoquinones
para-benzoquinones
CHEBI:132124
1,4-benzoquinones
a quinone
UniProt
p-benzoquinones
ChEBI
para-benzoquinones
ChEBI
Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa.
Wikipedia:Volatile_organic_compound
chebi_ontology
VOC
VOCs
volatile organic compounds
CHEBI:134179
volatile organic compound
VOC
ChEBI
VOCs
ChEBI
volatile organic compounds
ChEBI
An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups.
-1
CH2O3SR
94.091
93.97246
C(S([O-])(=O)=O)*
CHEBI:22318
MetaCyc:Alkanesulfonates
chebi_ontology
alkanesulfonate oxoanions
alkanesulfonates
an alkanesulfonate
CHEBI:134249
alkanesulfonate oxoanion
alkanesulfonate oxoanions
ChEBI
alkanesulfonates
ChEBI
an alkanesulfonate
UniProt
A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
glycols
chebi_ontology
Glykol
CHEBI:13643
glycol
glycols
IUPAC
Glykol
ChEBI
A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent.
PMID:26449612
chebi_ontology
pro-agents
proagent
proagents
CHEBI:136859
pro-agent
PMID:26449612
Europe PMC
pro-agents
ChEBI
proagent
ChEBI
proagents
ChEBI
An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included.
Wikipedia:Metalloid
chebi_ontology
metalloid
metalloids
CHEBI:137980
metalloid atom
metalloid
ChEBI
metalloids
ChEBI
Any compound that can disrupt the functions of the endocrine (hormone) system
PMID:27929035
PMID:28356401
PMID:28526231
Wikipedia:Endocrine_disruptor
chebi_ontology
endocrine disrupting chemical
endocrine disrupting chemicals
endocrine disrupting compound
endocrine disrupting compounds
endocrine disruptors
endocrine-disrupting chemical
endocrine-disrupting chemicals
hormonally active agent
hormonally active agents
CHEBI:138015
endocrine disruptor
PMID:27929035
Europe PMC
PMID:28356401
Europe PMC
PMID:28526231
Europe PMC
endocrine disrupting chemical
ChEBI
endocrine disrupting chemicals
ChEBI
endocrine disrupting compound
ChEBI
endocrine disrupting compounds
ChEBI
endocrine disruptors
ChEBI
endocrine-disrupting chemical
ChEBI
endocrine-disrupting chemicals
ChEBI
hormonally active agent
ChEBI
hormonally active agents
ChEBI
A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
Wikipedia:Mineral_acid
chebi_ontology
inorganic acids
mineral acid
mineral acids
CHEBI:138103
inorganic acid
inorganic acids
ChEBI
mineral acid
ChEBI
mineral acids
ChEBI
Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
Wikipedia:https://en.wikipedia.org/wiki/Gas
chebi_ontology
gas molecular entities
gaseous molecular entities
gaseous molecular entity
CHEBI:138675
gas molecular entity
gas molecular entities
ChEBI
gaseous molecular entities
ChEBI
gaseous molecular entity
ChEBI
-1
CH2NO2
InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1
KXDHJXZQYSOELW-UHFFFAOYSA-M
60.03212
60.00910
NC([O-])=O
Beilstein:3903503
CAS:302-11-4
Gmelin:239604
carbamate
FlyBase miscellaneous CV
chebi_ontology
Carbamat
Karbamat
carbamate ion
carbamic acid, ion(1-)
CHEBI:13941
carbamate
Beilstein:3903503
Beilstein
CAS:302-11-4
ChemIDplus
Gmelin:239604
Gmelin
carbamate
IUPAC
carbamate
UniProt
Carbamat
ChEBI
Karbamat
ChEBI
carbamate ion
ChemIDplus
carbamic acid, ion(1-)
ChemIDplus
A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound.
chebi_ontology
sensitisers
sensitizer
sensitizers
CHEBI:139492
sensitiser
sensitisers
ChEBI
sensitizer
ChEBI
sensitizers
ChEBI
Any methoxyflavanone having a methoxy substituent located at position 4'.
0
C16H5O3R9
245.210
245.02387
C1(=C(C(=C(C2=C1OC(C(C2=O)*)C3=C(C(=C(C(=C3*)*)OC)*)*)*)*)*)*
MetaCyc:4-Methoxyflavanones
2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
chebi_ontology
a 4'-methoxyflavanone
CHEBI:140332
4'-methoxyflavanones
MetaCyc:4-Methoxyflavanones
SUBMITTER
2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
IUPAC
a 4'-methoxyflavanone
UniProt
An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group
-1
C5H8NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1
WHUUTDBJXJRKMK-UHFFFAOYSA-M
146.12136
146.04588
[NH3+]C(CCC([O-])=O)C([O-])=O
Gmelin:327908
glutamate(1-)
hydrogen glutamate
chebi_ontology
2-ammoniopentanedioate
glutamate
glutamic acid monoanion
CHEBI:14321
glutamate(1-)
Gmelin:327908
Gmelin
glutamate(1-)
JCBN
hydrogen glutamate
IUPAC
2-ammoniopentanedioate
IUPAC
glutamate
UniProt
glutamic acid monoanion
JCBN
A purine nucleobase found in humans and other organisms.
0
C5H4N4O2
152.111
152.03343
ECMDB:ECMDB00292
KNApSAcK:C00019660
PMID:1557408
PMID:24629268
PMID:9007687
YMDB:YMDB00263
xanthine
chebi_ontology
2,6-dioxopurine
2,6-dioxopurines
xanthines
CHEBI:15318
xanthine
PMID:1557408
Europe PMC
PMID:24629268
Europe PMC
PMID:9007687
Europe PMC
xanthine
ChEBI
2,6-dioxopurine
ChEBI
2,6-dioxopurines
ChEBI
xanthines
ChEBI
A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
CHEBI:13699
CHEBI:2377
KEGG:C00028
KEGG:C16722
Acceptor
chebi_ontology
A
Akzeptor
Hydrogen-acceptor
Oxidized donor
accepteur
CHEBI:15339
acceptor
Acceptor
KEGG_COMPOUND
A
KEGG_COMPOUND
Akzeptor
ChEBI
Hydrogen-acceptor
KEGG_COMPOUND
Oxidized donor
KEGG_COMPOUND
accepteur
ChEBI
A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.
0
C3H7NO2S
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
XUJNEKJLAYXESH-UHFFFAOYSA-N
121.15922
121.01975
NC(CS)C(O)=O
CHEBI:14061
CHEBI:23508
CHEBI:4050
Beilstein:1721406
CAS:3374-22-9
Gmelin:2933
KEGG:C00736
KNApSAcK:C00001351
KNApSAcK:C00007323
PMID:17439666
PMID:25181601
Reaxys:1721406
Wikipedia:Cysteine
Cysteine
cysteine
chebi_ontology
2-Amino-3-mercaptopropionic acid
2-amino-3-mercaptopropanoic acid
2-amino-3-sulfanylpropanoic acid
C
Cys
Cystein
Hcys
Zystein
cisteina
CHEBI:15356
cysteine
Beilstein:1721406
Beilstein
CAS:3374-22-9
ChemIDplus
CAS:3374-22-9
KEGG COMPOUND
CAS:3374-22-9
NIST Chemistry WebBook
Gmelin:2933
Gmelin
PMID:17439666
Europe PMC
PMID:25181601
Europe PMC
Reaxys:1721406
Reaxys
Cysteine
KEGG_COMPOUND
cysteine
ChEBI
cysteine
IUPAC
2-Amino-3-mercaptopropionic acid
KEGG_COMPOUND
2-amino-3-mercaptopropanoic acid
JCBN
2-amino-3-sulfanylpropanoic acid
IUPAC
C
ChEBI
Cys
ChEBI
Cystein
ChEBI
Hcys
IUPAC
Zystein
ChEBI
cisteina
ChEBI
A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides.
CHEBI:13723
CHEBI:22220
CHEBI:2445
CAS:1402-38-6
KEGG:C01775
Actinomycin
chebi_ontology
actinomycins
CHEBI:15369
actinomycin
CAS:1402-38-6
ChemIDplus
CAS:1402-38-6
KEGG COMPOUND
Actinomycin
KEGG_COMPOUND
actinomycins
ChEBI
Any alpha-amino acid having L-configuration at the alpha-carbon.
0
C2H4NO2R
74.05870
74.02420
N[C@@H]([*])C(O)=O
CHEBI:13072
CHEBI:13243
CHEBI:13797
CHEBI:21224
CHEBI:6175
KEGG:C00151
L-alpha-amino acid
L-alpha-amino acids
chebi_ontology
L-2-Amino acid
L-Amino acid
L-alpha-amino acids
CHEBI:15705
L-alpha-amino acid
L-alpha-amino acid
IUPAC
L-alpha-amino acids
IUPAC
L-2-Amino acid
KEGG_COMPOUND
L-Amino acid
KEGG_COMPOUND
L-alpha-amino acids
ChEBI
A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects.
-1
CHO2
InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1
BDAGIHXWWSANSR-UHFFFAOYSA-M
45.01744
44.99820
[H]C([O-])=O
CHEBI:14276
CHEBI:24081
Beilstein:1901205
CAS:71-47-6
Gmelin:1006
HMDB:HMDB0000142
KEGG:C00058
MetaCyc:FORMATE
PMID:17190852
PMID:3946945
Reaxys:1901205
UM-BBD_compID:c0106
Wikipedia:Formate
formate
chebi_ontology
HCO2 anion
aminate
formiate
formic acid, ion(1-)
formylate
hydrogen carboxylate
methanoate
CHEBI:15740
formate
Beilstein:1901205
Beilstein
CAS:71-47-6
ChemIDplus
CAS:71-47-6
NIST Chemistry WebBook
Gmelin:1006
Gmelin
PMID:17190852
Europe PMC
PMID:3946945
Europe PMC
Reaxys:1901205
Reaxys
UM-BBD_compID:c0106
UM-BBD
formate
IUPAC
formate
UniProt
HCO2 anion
NIST_Chemistry_WebBook
aminate
ChEBI
formiate
ChEBI
formic acid, ion(1-)
ChemIDplus
formylate
ChEBI
hydrogen carboxylate
ChEBI
methanoate
ChEBI
Any N-acyl-amino acid in which the amino acid moiety has D configuration.
0
C3H3NO3R2
101.06080
101.01129
OC(=O)[C@@H]([*])NC([*])=O
CHEBI:12474
CHEBI:21631
CHEBI:7224
chebi_ontology
CHEBI:15778
N-acyl-D-amino acid
An optically active form of glutamic acid having D-configuration.
0
C5H9NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
WHUUTDBJXJRKMK-GSVOUGTGSA-N
147.12930
147.05316
N[C@H](CCC(O)=O)C(O)=O
CHEBI:21023
CHEBI:4183
Beilstein:1723800
CAS:6893-26-1
DrugBank:DB02517
Gmelin:201189
HMDB:HMDB0003339
KEGG:C00217
KNApSAcK:C00019577
MetaCyc:D-GLT
PDBeChem:DGL
Reaxys:1723800
(2R)-2-aminopentanedioic acid
D-Glutamic acid
D-glutamic acid
chebi_ontology
(R)-2-aminopentanedioic acid
D-2-Aminoglutaric acid
D-Glutaminic acid
D-Glutaminsaeure
DGL
glutamic acid D-form
CHEBI:15966
D-glutamic acid
Beilstein:1723800
Beilstein
CAS:6893-26-1
ChemIDplus
CAS:6893-26-1
KEGG COMPOUND
CAS:6893-26-1
NIST Chemistry WebBook
Gmelin:201189
Gmelin
Reaxys:1723800
Reaxys
(2R)-2-aminopentanedioic acid
IUPAC
D-Glutamic acid
KEGG_COMPOUND
D-glutamic acid
IUPAC
(R)-2-aminopentanedioic acid
ChEBI
D-2-Aminoglutaric acid
KEGG_COMPOUND
D-Glutaminic acid
KEGG_COMPOUND
D-Glutaminsaeure
ChEBI
DGL
PDBeChem
glutamic acid D-form
ChemIDplus
A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues.
0
(C5H8O6PR)n.C10H17O10PR2
CHEBI:13672
CHEBI:14859
CHEBI:8312
KEGG:C00419
Polynucleotide
chebi_ontology
polynucleotides
CHEBI:15986
polynucleotide
Polynucleotide
KEGG_COMPOUND
polynucleotides
ChEBI
An optically active form of glutamic acid having L-configuration.
0
C5H9NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
WHUUTDBJXJRKMK-VKHMYHEASA-N
147.12930
147.05316
N[C@@H](CCC(O)=O)C(O)=O
CHEBI:21304
CHEBI:42825
CHEBI:6224
BPDB:2297
Beilstein:1723801
CAS:56-86-0
DrugBank:DB00142
Drug_Central:1310
Gmelin:3502
HMDB:HMDB0000148
KEGG:C00025
KEGG:D00007
KNApSAcK:C00001358
LINCS:LSM-36375
MetaCyc:GLT
PDBeChem:GLU_LFOH
PMID:15739367
PMID:15930465
PMID:16719819
PMID:16892196
PMID:19581495
PMID:22219301
PMID:22735334
Reaxys:1723801
Wikipedia:L-Glutamic_Acid
(2S)-2-aminopentanedioic acid
L-Glutamic acid
L-glutamic acid
chebi_ontology
(S)-2-aminopentanedioic acid
(S)-glutamic acid
E
GLUTAMIC ACID
Glu
Glutamate
L-Glu
L-Glutaminic acid
L-Glutaminsaeure
acide glutamique
acido glutamico
acidum glutamicum
glutamic acid
CHEBI:16015
L-glutamic acid
Beilstein:1723801
Beilstein
CAS:56-86-0
ChemIDplus
CAS:56-86-0
KEGG COMPOUND
CAS:56-86-0
NIST Chemistry WebBook
Drug_Central:1310
DrugCentral
Gmelin:3502
Gmelin
PMID:15739367
Europe PMC
PMID:15930465
Europe PMC
PMID:16719819
Europe PMC
PMID:16892196
Europe PMC
PMID:19581495
Europe PMC
PMID:22219301
Europe PMC
PMID:22735334
Europe PMC
Reaxys:1723801
Reaxys
(2S)-2-aminopentanedioic acid
IUPAC
L-Glutamic acid
KEGG_COMPOUND
L-glutamic acid
IUPAC
(S)-2-aminopentanedioic acid
ChEBI
(S)-glutamic acid
NIST_Chemistry_WebBook
E
ChEBI
GLUTAMIC ACID
PDBeChem
Glu
ChEBI
Glutamate
KEGG_COMPOUND
L-Glu
ChEBI
L-Glutaminic acid
KEGG_COMPOUND
L-Glutaminsaeure
ChEBI
acide glutamique
ChEBI
acido glutamico
ChEBI
acidum glutamicum
ChEBI
glutamic acid
ChEBI
A monoatomic monoanion resulting from the addition of an electron to any halogen atom.
-1
X
0.0
0.0
[*-]
CHEBI:14384
CHEBI:5605
KEGG:C00462
halide ions
chebi_ontology
HX
Halide
a halide anion
halide anions
halide(1-)
halides
halogen anion
CHEBI:16042
halide anion
halide ions
IUPAC
HX
KEGG_COMPOUND
Halide
KEGG_COMPOUND
a halide anion
UniProt
halide anions
ChEBI
halide(1-)
ChEBI
halides
ChEBI
halogen anion
ChEBI
An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
0
H3N
InChI=1S/H3N/h1H3
QGZKDVFQNNGYKY-UHFFFAOYSA-N
17.03056
17.02655
[H]N([H])[H]
CHEBI:13405
CHEBI:13406
CHEBI:13407
CHEBI:13771
CHEBI:22533
CHEBI:44269
CHEBI:44284
CHEBI:44404
CHEBI:7434
Beilstein:3587154
CAS:7664-41-7
Drug_Central:4625
Gmelin:79
HMDB:HMDB0000051
KEGG:C00014
KEGG:D02916
KNApSAcK:C00007267
MetaCyc:AMMONIA
MolBase:930
PDBeChem:NH3
PMID:110589
PMID:11139349
PMID:11540049
PMID:11746427
PMID:11783653
PMID:13753780
PMID:14663195
PMID:15092448
PMID:15094021
PMID:15554424
PMID:15969015
PMID:16008360
PMID:16050680
PMID:16348008
PMID:16349403
PMID:16614889
PMID:16664306
PMID:16842901
PMID:17025297
PMID:17439666
PMID:17569513
PMID:17737668
PMID:18670398
PMID:22002069
PMID:22081570
PMID:22088435
PMID:22100291
PMID:22130175
PMID:22150211
PMID:22240068
PMID:22290316
PMID:22342082
PMID:22385337
PMID:22443779
PMID:22560242
Reaxys:3587154
Wikipedia:Ammonia
AMMONIA
Ammonia
ammonia
azane
chebi_ontology
Ammoniak
NH3
R-717
[NH3]
ammoniac
amoniaco
spirit of hartshorn
CHEBI:16134
ammonia
Beilstein:3587154
Beilstein
CAS:7664-41-7
ChemIDplus
CAS:7664-41-7
KEGG COMPOUND
CAS:7664-41-7
NIST Chemistry WebBook
Drug_Central:4625
DrugCentral
Gmelin:79
Gmelin
PMID:110589
Europe PMC
PMID:11139349
Europe PMC
PMID:11540049
Europe PMC
PMID:11746427
Europe PMC
PMID:11783653
Europe PMC
PMID:13753780
Europe PMC
PMID:14663195
Europe PMC
PMID:15092448
Europe PMC
PMID:15094021
Europe PMC
PMID:15554424
Europe PMC
PMID:15969015
Europe PMC
PMID:16008360
Europe PMC
PMID:16050680
Europe PMC
PMID:16348008
Europe PMC
PMID:16349403
Europe PMC
PMID:16614889
Europe PMC
PMID:16664306
Europe PMC
PMID:16842901
Europe PMC
PMID:17025297
Europe PMC
PMID:17439666
Europe PMC
PMID:17569513
Europe PMC
PMID:17737668
Europe PMC
PMID:18670398
Europe PMC
PMID:22002069
Europe PMC
PMID:22081570
Europe PMC
PMID:22088435
Europe PMC
PMID:22100291
Europe PMC
PMID:22130175
Europe PMC
PMID:22150211
Europe PMC
PMID:22240068
Europe PMC
PMID:22290316
Europe PMC
PMID:22342082
Europe PMC
PMID:22385337
Europe PMC
PMID:22443779
Europe PMC
PMID:22560242
Europe PMC
Reaxys:3587154
Reaxys
AMMONIA
PDBeChem
Ammonia
KEGG_COMPOUND
ammonia
IUPAC
azane
IUPAC
Ammoniak
ChemIDplus
NH3
IUPAC
NH3
KEGG_COMPOUND
NH3
UniProt
R-717
ChEBI
[NH3]
MolBase
ammoniac
ChEBI
amoniaco
ChEBI
spirit of hartshorn
ChemIDplus
A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid.
-2
O4S
InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
QAOWNCQODCNURD-UHFFFAOYSA-L
96.06360
95.95283
[O-]S([O-])(=O)=O
CHEBI:15135
CHEBI:45687
CHEBI:9335
Beilstein:3648446
CAS:14808-79-8
Gmelin:2120
HMDB:HMDB0001448
KEGG:C00059
KEGG:D05963
MetaCyc:SULFATE
PDBeChem:SO4
PMID:11200094
PMID:11452993
PMID:11581495
PMID:11798107
PMID:12166931
PMID:12668033
PMID:14597181
PMID:15093386
PMID:15984785
PMID:16186560
PMID:16345535
PMID:16347366
PMID:16348007
PMID:16483812
PMID:16534979
PMID:16656509
PMID:16742508
PMID:16742518
PMID:17120760
PMID:17420092
PMID:17439666
PMID:17709180
PMID:18398178
PMID:18815700
PMID:18846414
PMID:19047345
PMID:19244483
PMID:19544990
PMID:19628332
PMID:19812358
PMID:30398859
Reaxys:3648446
Wikipedia:Sulfate
Sulfate
sulfate
tetraoxidosulfate(2-)
tetraoxosulfate(2-)
tetraoxosulfate(VI)
chebi_ontology
SO4(2-)
SULFATE ION
Sulfate anion(2-)
Sulfate dianion
Sulfate(2-)
Sulfuric acid ion(2-)
[SO4](2-)
sulphate
sulphate ion
CHEBI:16189
sulfate
Beilstein:3648446
Beilstein
CAS:14808-79-8
ChemIDplus
CAS:14808-79-8
NIST Chemistry WebBook
Gmelin:2120
Gmelin
PMID:11200094
Europe PMC
PMID:11452993
Europe PMC
PMID:11581495
Europe PMC
PMID:11798107
Europe PMC
PMID:12166931
Europe PMC
PMID:12668033
Europe PMC
PMID:14597181
Europe PMC
PMID:15093386
Europe PMC
PMID:15984785
Europe PMC
PMID:16186560
Europe PMC
PMID:16345535
Europe PMC
PMID:16347366
Europe PMC
PMID:16348007
Europe PMC
PMID:16483812
Europe PMC
PMID:16534979
Europe PMC
PMID:16656509
Europe PMC
PMID:16742508
Europe PMC
PMID:16742518
Europe PMC
PMID:17120760
Europe PMC
PMID:17420092
Europe PMC
PMID:17439666
Europe PMC
PMID:17709180
Europe PMC
PMID:18398178
Europe PMC
PMID:18815700
Europe PMC
PMID:18846414
Europe PMC
PMID:19047345
Europe PMC
PMID:19244483
Europe PMC
PMID:19544990
Europe PMC
PMID:19628332
Europe PMC
PMID:19812358
Europe PMC
PMID:30398859
Europe PMC
Reaxys:3648446
Reaxys
Sulfate
KEGG_COMPOUND
sulfate
IUPAC
sulfate
UniProt
tetraoxidosulfate(2-)
IUPAC
tetraoxosulfate(2-)
IUPAC
tetraoxosulfate(VI)
IUPAC
SO4(2-)
IUPAC
SULFATE ION
PDBeChem
Sulfate anion(2-)
HMDB
Sulfate dianion
HMDB
Sulfate(2-)
HMDB
Sulfuric acid ion(2-)
HMDB
[SO4](2-)
IUPAC
sulphate
ChEBI
sulphate ion
ChEBI
A carbonyl group with two C-bound amine groups.
0
CH4N2O
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
XSQUKJJJFZCRTK-UHFFFAOYSA-N
60.05534
60.03236
NC(N)=O
CHEBI:15292
CHEBI:27218
CHEBI:46379
CHEBI:9888
Beilstein:635724
CAS:57-13-6
DrugBank:DB03904
Drug_Central:4264
ECMDB:ECMDB04172
Gmelin:1378
HMDB:HMDB0000294
KEGG:C00086
KEGG:D00023
KNApSAcK:C00007314
MetaCyc:UREA
PDBeChem:URE
PMID:18037357
PMID:22770225
PPDB:1728
Reaxys:635724
UM-BBD_compID:c0165
Wikipedia:Urea
YMDB:YMDB00003
UREA
Urea
urea
chebi_ontology
1728
Carbamide
E927b
H2NC(O)NH2
Harnstoff
Karbamid
carbamide
carbonyldiamide
ur
uree
CHEBI:16199
urea
Beilstein:635724
Beilstein
CAS:57-13-6
ChemIDplus
CAS:57-13-6
KEGG COMPOUND
CAS:57-13-6
NIST Chemistry WebBook
Drug_Central:4264
DrugCentral
Gmelin:1378
Gmelin
PMID:18037357
Europe PMC
PMID:22770225
Europe PMC
Reaxys:635724
Reaxys
UM-BBD_compID:c0165
UM-BBD
UREA
PDBeChem
Urea
KEGG_COMPOUND
urea
IUPAC
urea
UniProt
1728
PPDB
Carbamide
KEGG_COMPOUND
E927b
ChEBI
H2NC(O)NH2
ChEBI
Harnstoff
NIST_Chemistry_WebBook
Karbamid
ChEBI
carbamide
ChEBI
carbonyldiamide
NIST_Chemistry_WebBook
ur
IUPAC
uree
ChEBI
A 2-aminopurine carrying a 6-oxo substituent.
0
C5H5N5O
InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
UYTPUPDQBNUYGX-UHFFFAOYSA-N
151.126
151.04941
C12=C(N=C(NC1=O)N)NC=N2
CHEBI:14371
CHEBI:14372
CHEBI:24443
CHEBI:42948
CHEBI:5563
Beilstein:147911
CAS:73-40-5
DrugBank:DB02377
Gmelin:431879
HMDB:HMDB0000132
KEGG:C00242
KNApSAcK:C00001501
MetaCyc:GUANINE
PDBeChem:GUN
PMID:22770225
PMID:8070089
Reaxys:147911
Wikipedia:Guanine
2-amino-1,9-dihydro-6H-purin-6-one
GUANINE
Guanine
guanine
chebi_ontology
2-Amino-6-hydroxypurine
2-amino-6-oxopurine
G
Gua
CHEBI:16235
guanine
Beilstein:147911
Beilstein
CAS:73-40-5
ChemIDplus
CAS:73-40-5
KEGG COMPOUND
CAS:73-40-5
NIST Chemistry WebBook
Gmelin:431879
Gmelin
PMID:22770225
Europe PMC
PMID:8070089
Europe PMC
Reaxys:147911
Reaxys
2-amino-1,9-dihydro-6H-purin-6-one
IUPAC
GUANINE
PDBeChem
Guanine
KEGG_COMPOUND
guanine
UniProt
2-Amino-6-hydroxypurine
KEGG_COMPOUND
2-amino-6-oxopurine
ChEBI
G
ChEBI
Gua
CBN
Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers.
0
SR2
32.066
31.97207
CHEBI:13694
CHEBI:26960
CHEBI:9340
KEGG:C00297
sulfides
chebi_ontology
RSR
Sulfide
Thioether
organic sulfides
thioethers
CHEBI:16385
organic sulfide
sulfides
IUPAC
RSR
IUPAC
Sulfide
KEGG_COMPOUND
Thioether
KEGG_COMPOUND
organic sulfides
ChEBI
thioethers
IUPAC
An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia.
0
C10H8
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H
UFWIBTONFRDIAS-UHFFFAOYSA-N
128.17052
128.06260
c1ccc2ccccc2c1
CHEBI:14638
CHEBI:25469
CHEBI:44619
CHEBI:7472
Beilstein:1421310
CAS:91-20-3
Gmelin:3347
HMDB:HMDB0029751
KEGG:C00829
KNApSAcK:C00001259
MetaCyc:NAPHTHALENE
PDBeChem:NPY
PMID:10814889
PMID:11202734
PMID:16220979
PMID:16699520
PMID:17850896
PMID:26875834
PMID:26895256
PMID:27439360
PPDB:1312
Reaxys:1421310
UM-BBD_compID:c0333
Wikipedia:Naphthalene
NAPHTHALENE
Naphthalene
naphthalene
chebi_ontology
Naphthalen
Naphthalin
naftaleno
naftalina
naphtalene
naphtaline
CHEBI:16482
naphthalene
Beilstein:1421310
Beilstein
CAS:91-20-3
ChemIDplus
CAS:91-20-3
KEGG COMPOUND
CAS:91-20-3
NIST Chemistry WebBook
Gmelin:3347
Gmelin
PMID:10814889
Europe PMC
PMID:11202734
Europe PMC
PMID:16220979
Europe PMC
PMID:16699520
Europe PMC
PMID:17850896
Europe PMC
PMID:26875834
Europe PMC
PMID:26895256
Europe PMC
PMID:27439360
Europe PMC
Reaxys:1421310
Reaxys
UM-BBD_compID:c0333
UM-BBD
NAPHTHALENE
PDBeChem
Naphthalene
KEGG_COMPOUND
naphthalene
IUPAC
naphthalene
UniProt
Naphthalen
ChEBI
Naphthalin
NIST_Chemistry_WebBook
naftaleno
ChEBI
naftalina
ChEBI
naphtalene
ChEBI
naphtaline
ChEBI
The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
0
C6H4O2
InChI=1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H
AZQWKYJCGOJGHM-UHFFFAOYSA-N
108.09480
108.02113
O=C1C=CC(=O)C=C1
CHEBI:12837
CHEBI:15009
CHEBI:18927
CHEBI:49820
CHEBI:8730
Beilstein:773967
CAS:106-51-4
Gmelin:2741
HMDB:HMDB0003364
KEGG:C00472
KEGG:C15602
MetaCyc:P-BENZOQUINONE
PDBeChem:PLQ
PMID:10462055
PMID:11304127
PMID:1395635
PMID:15182198
PMID:15618234
PMID:15920754
PMID:16484134
PMID:24023812
PMID:25057895
PMID:9118901
Reaxys:773967
UM-BBD_compID:c0261
Wikipedia:1,4-Benzoquinone
1,4-Benzoquinone
1,4-benzoquinone
cyclohexa-2,5-diene-1,4-dione
chebi_ontology
1,4-Benzochinon
2,5-Cyclohexadiene-1,4-dione
Quinone
benzo-1,4-quinone
benzoquinone
p-Benzoquinone
p-Chinon
p-quinone
para-benzoquinone
CHEBI:16509
1,4-benzoquinone
Beilstein:773967
Beilstein
CAS:106-51-4
ChemIDplus
CAS:106-51-4
KEGG COMPOUND
CAS:106-51-4
NIST Chemistry WebBook
Gmelin:2741
Gmelin
PMID:10462055
Europe PMC
PMID:11304127
Europe PMC
PMID:1395635
Europe PMC
PMID:15182198
Europe PMC
PMID:15618234
Europe PMC
PMID:15920754
Europe PMC
PMID:16484134
Europe PMC
PMID:24023812
Europe PMC
PMID:25057895
Europe PMC
PMID:9118901
Europe PMC
Reaxys:773967
Reaxys
UM-BBD_compID:c0261
UM-BBD
1,4-Benzoquinone
KEGG_COMPOUND
1,4-benzoquinone
NIST_Chemistry_WebBook
1,4-benzoquinone
UniProt
cyclohexa-2,5-diene-1,4-dione
IUPAC
1,4-Benzochinon
ChEBI
2,5-Cyclohexadiene-1,4-dione
KEGG_COMPOUND
Quinone
KEGG_COMPOUND
benzo-1,4-quinone
NIST_Chemistry_WebBook
benzoquinone
ChemIDplus
p-Benzoquinone
KEGG_COMPOUND
p-Chinon
NIST_Chemistry_WebBook
p-quinone
HMDB
para-benzoquinone
HMDB
Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates.
CHEBI:15131
CHEBI:23008
CHEBI:9318
Wikipedia:Carbohydrate
carbohydrate
carbohydrates
chebi_ontology
Kohlenhydrat
Kohlenhydrate
carbohidrato
carbohidratos
glucide
glucides
glucido
glucidos
hydrates de carbone
saccharide
saccharides
saccharidum
CHEBI:16646
carbohydrate
carbohydrate
IUPAC
carbohydrates
IUPAC
Kohlenhydrat
ChEBI
Kohlenhydrate
ChEBI
carbohidrato
IUPAC
carbohidratos
IUPAC
glucide
ChEBI
glucides
ChEBI
glucido
ChEBI
glucidos
ChEBI
hydrates de carbone
ChEBI
saccharide
IUPAC
saccharides
IUPAC
saccharidum
ChEBI
Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
0
(C2H2NOR)nC2H3NOR
CHEBI:14753
CHEBI:25906
CHEBI:7990
KEGG:C00012
Peptide
peptides
chebi_ontology
Peptid
peptido
peptidos
CHEBI:16670
peptide
Peptide
KEGG_COMPOUND
peptides
IUPAC
Peptid
ChEBI
peptido
ChEBI
peptidos
ChEBI
A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system.
0
C6H6
InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
UHOVQNZJYSORNB-UHFFFAOYSA-N
78.11184
78.04695
c1ccccc1
CHEBI:13876
CHEBI:22703
CHEBI:3025
CHEBI:41187
Beilstein:969212
CAS:71-43-2
Gmelin:1671
HMDB:HMDB0001505
KEGG:C01407
PDBeChem:BNZ
PMID:11684179
PMID:11993966
PMID:12857942
PMID:14677922
PMID:15468289
PMID:15935818
PMID:16161967
PMID:17373369
PMID:18072742
PMID:18407866
PMID:18409691
PMID:18836923
PMID:19228219
PMID:21325737
PMID:23088855
PMID:23222815
PMID:23534829
PMID:6353911
PMID:8124204
Reaxys:969212
UM-BBD_compID:c0142
Wikipedia:Benzene
BENZENE
Benzene
benzene
chebi_ontology
Benzen
Benzine
Benzol
Bicarburet of hydrogen
Coal naphtha
Mineral naphtha
Phene
Pyrobenzol
Pyrobenzole
[6]annulene
benzole
cyclohexatriene
phenyl hydride
CHEBI:16716
benzene
Beilstein:969212
Beilstein
CAS:71-43-2
ChemIDplus
CAS:71-43-2
KEGG COMPOUND
CAS:71-43-2
NIST Chemistry WebBook
Gmelin:1671
Gmelin
PMID:11684179
Europe PMC
PMID:11993966
Europe PMC
PMID:12857942
Europe PMC
PMID:14677922
Europe PMC
PMID:15468289
Europe PMC
PMID:15935818
Europe PMC
PMID:16161967
Europe PMC
PMID:17373369
Europe PMC
PMID:18072742
Europe PMC
PMID:18407866
Europe PMC
PMID:18409691
Europe PMC
PMID:18836923
Europe PMC
PMID:19228219
Europe PMC
PMID:21325737
Europe PMC
PMID:23088855
Europe PMC
PMID:23222815
Europe PMC
PMID:23534829
Europe PMC
PMID:6353911
Europe PMC
PMID:8124204
Europe PMC
Reaxys:969212
Reaxys
UM-BBD_compID:c0142
UM-BBD
BENZENE
PDBeChem
Benzene
KEGG_COMPOUND
benzene
ChEBI
benzene
IUPAC
benzene
UniProt
Benzen
IUPAC
Benzine
UM-BBD
Benzol
ChemIDplus
Bicarburet of hydrogen
ChemIDplus
Coal naphtha
ChemIDplus
Mineral naphtha
ChemIDplus
Phene
ChemIDplus
Pyrobenzol
ChemIDplus
Pyrobenzole
ChemIDplus
[6]annulene
NIST_Chemistry_WebBook
benzole
NIST_Chemistry_WebBook
cyclohexatriene
UM-BBD
phenyl hydride
UM-BBD
0
C2H4NO2R
74.05870
74.02420
N[C@H]([*])C(O)=O
CHEBI:12909
CHEBI:13625
CHEBI:20906
CHEBI:4097
KEGG:C00405
D-alpha-amino acid
D-alpha-amino acids
chebi_ontology
D-Amino acid
D-alpha-amino acids
CHEBI:16733
D-alpha-amino acid
D-alpha-amino acid
ChEBI
D-alpha-amino acids
IUPAC
D-Amino acid
KEGG_COMPOUND
D-alpha-amino acids
ChEBI
An aldehyde resulting from the formal oxidation of methanol.
0
CH2O
InChI=1S/CH2O/c1-2/h1H2
WSFSSNUMVMOOMR-UHFFFAOYSA-N
30.02598
30.01056
[H]C([H])=O
CHEBI:14274
CHEBI:24077
CHEBI:337763
CHEBI:5142
Beilstein:1209228
CAS:50-00-0
DrugBank:DB03843
Drug_Central:3244
Gmelin:445
HMDB:HMDB0001426
KEGG:C00067
KEGG:D00017
PDBeChem:FLH
PDBeChem:FOR
PMID:110589
PMID:12686735
PMID:15091529
PMID:16423181
PMID:17618393
PMID:18837732
PMID:25042713
PMID:7381846
PMID:7548723
PMID:7689168
PMID:7896413
PMID:9686972
PPDB:359
Reaxys:1209228
UM-BBD_compID:c0122
Wikipedia:Formaldehyde
FORMALDEHYDE
Formaldehyde
formaldehyde
FlyBase miscellaneous CV
chebi_ontology
FORMALIN
Formaldehyd
Formalin
Methanal
Methylene oxide
Oxomethane
Oxomethylene
CHEBI:16842
formaldehyde
Beilstein:1209228
Beilstein
CAS:50-00-0
ChemIDplus
CAS:50-00-0
KEGG COMPOUND
CAS:50-00-0
NIST Chemistry WebBook
Drug_Central:3244
DrugCentral
Gmelin:445
Gmelin
PMID:110589
Europe PMC
PMID:12686735
Europe PMC
PMID:15091529
Europe PMC
PMID:16423181
Europe PMC
PMID:17618393
Europe PMC
PMID:18837732
Europe PMC
PMID:25042713
Europe PMC
PMID:7381846
ChEMBL
PMID:7548723
Europe PMC
PMID:7689168
Europe PMC
PMID:7896413
Europe PMC
PMID:9686972
Europe PMC
Reaxys:1209228
Reaxys
UM-BBD_compID:c0122
UM-BBD
FORMALDEHYDE
PDBeChem
Formaldehyde
KEGG_COMPOUND
formaldehyde
IUPAC
formaldehyde
UniProt
FORMALIN
ChEMBL
Formaldehyd
NIST_Chemistry_WebBook
Formalin
KEGG_COMPOUND
Methanal
KEGG_COMPOUND
Methylene oxide
KEGG_COMPOUND
Oxomethane
KEGG_COMPOUND
Oxomethylene
KEGG_COMPOUND
High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
CHEBI:13302
CHEBI:21123
CHEBI:33698
CHEBI:4291
CAS:9007-49-2
KEGG:C00039
Deoxyribonucleic acid
deoxyribonucleic acids
FlyBase miscellaneous CV
chebi_ontology
(Deoxyribonucleotide)m
(Deoxyribonucleotide)n
(Deoxyribonucleotide)n+m
DNA
DNAn
DNAn+1
DNS
Desoxyribonukleinsaeure
deoxyribonucleic acids
desoxyribose nucleic acid
thymus nucleic acid
CHEBI:16991
deoxyribonucleic acid
CAS:9007-49-2
ChemIDplus
CAS:9007-49-2
KEGG COMPOUND
Deoxyribonucleic acid
KEGG_COMPOUND
deoxyribonucleic acids
IUPAC
(Deoxyribonucleotide)m
KEGG_COMPOUND
(Deoxyribonucleotide)n
KEGG_COMPOUND
(Deoxyribonucleotide)n+m
KEGG_COMPOUND
DNA
IUPAC
DNA
KEGG_COMPOUND
DNAn
KEGG_COMPOUND
DNAn+1
KEGG_COMPOUND
DNS
ChEBI
Desoxyribonukleinsaeure
ChEBI
deoxyribonucleic acids
ChEBI
desoxyribose nucleic acid
ChemIDplus
thymus nucleic acid
ChEBI
The D-enantiomer of phenylalanine.
0
C9H11NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
COLNVLDHVKWLRT-MRVPVSSYSA-N
165.18918
165.07898
N[C@H](Cc1ccccc1)C(O)=O
CHEBI:13007
CHEBI:21067
CHEBI:42207
CHEBI:4224
Beilstein:2804068
CAS:673-06-3
DrugBank:DB02556
ECMDB:ECMDB20144
Gmelin:83219
KEGG:C02265
MetaCyc:CPD-216
PDBeChem:DPN
PMID:22382026
PMID:22397264
PMID:24464217
PMID:7114516
Reaxys:2804068
YMDB:YMDB00995
(2R)-2-amino-3-phenylpropanoic acid
D-PHENYLALANINE
D-Phenylalanine
D-phenylalanine
chebi_ontology
D-Phe
D-alpha-Amino-beta-phenylpropionic acid
DPN
phenylalanine D-form
CHEBI:16998
D-phenylalanine
Beilstein:2804068
Beilstein
CAS:673-06-3
ChemIDplus
CAS:673-06-3
KEGG COMPOUND
Gmelin:83219
Gmelin
PMID:22382026
Europe PMC
PMID:22397264
Europe PMC
PMID:24464217
Europe PMC
PMID:7114516
Europe PMC
Reaxys:2804068
Reaxys
(2R)-2-amino-3-phenylpropanoic acid
IUPAC
D-PHENYLALANINE
PDBeChem
D-Phenylalanine
KEGG_COMPOUND
D-phenylalanine
IUPAC
D-Phe
ChEBI
D-alpha-Amino-beta-phenylpropionic acid
KEGG_COMPOUND
DPN
PDBeChem
phenylalanine D-form
ChemIDplus
-1
F
InChI=1S/FH/h1H/p-1
KRHYYFGTRYWZRS-UHFFFAOYSA-M
18.99840
18.99895
[F-]
CHEBI:14271
CHEBI:49593
CHEBI:5113
CAS:16984-48-8
Gmelin:14905
KEGG:C00742
PDBeChem:F
Fluoride
fluoride
fluoride(1-)
chebi_ontology
F(-)
F-
FLUORIDE ION
Fluoride ion
Fluorine anion
CHEBI:17051
fluoride
CAS:16984-48-8
ChemIDplus
CAS:16984-48-8
NIST Chemistry WebBook
Gmelin:14905
Gmelin
Fluoride
KEGG_COMPOUND
fluoride
IUPAC
fluoride
UniProt
fluoride(1-)
IUPAC
F(-)
IUPAC
F-
KEGG_COMPOUND
FLUORIDE ION
PDBeChem
Fluoride ion
KEGG_COMPOUND
Fluorine anion
NIST_Chemistry_WebBook
A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
0
COR2
28.010
27.99491
[*]C([*])=O
CHEBI:13427
CHEBI:13646
CHEBI:24974
CHEBI:6127
CHEBI:8742
KEGG:C01450
Wikipedia:Ketone
Ketone
ketones
chebi_ontology
Keton
R-CO-R'
a ketone
cetone
ketones
CHEBI:17087
ketone
Ketone
KEGG_COMPOUND
ketones
IUPAC
Keton
ChEBI
R-CO-R'
KEGG_COMPOUND
a ketone
UniProt
cetone
ChEBI
ketones
ChEBI
A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2).
CHEBI:14827
CHEBI:26076
CHEBI:8162
chebi_ontology
phosphamide
phosphamides
phosphoramides
CHEBI:17102
phosphoramide
phosphamide
ChEBI
phosphamides
ChEBI
phosphoramides
ChEBI
-1
HO3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1
LSNNMFCWUKXFEE-UHFFFAOYSA-M
81.07214
80.96519
OS([O-])=O
CHEBI:13367
CHEBI:5598
CAS:15181-46-1
Gmelin:1455
KEGG:C11481
PDBeChem:SO3
hydrogen(trioxidosulfate)(1-)
hydrogensulfite(1-)
hydrogentrioxosulfate(1-)
hydrogentrioxosulfate(IV)
hydroxidodioxidosulfate(1-)
monohydrogentrioxosulfate
chebi_ontology
Bisulfite
HSO3(-)
HSO3-
Hydrogen sulfite
[SO2(OH)](-)
bisulfite
bisulphite
hydrogen sulfite(1-)
hydrosulfite anion
CHEBI:17137
hydrogensulfite
CAS:15181-46-1
ChemIDplus
CAS:15181-46-1
KEGG COMPOUND
Gmelin:1455
Gmelin
hydrogen(trioxidosulfate)(1-)
IUPAC
hydrogensulfite(1-)
IUPAC
hydrogentrioxosulfate(1-)
IUPAC
hydrogentrioxosulfate(IV)
IUPAC
hydroxidodioxidosulfate(1-)
IUPAC
monohydrogentrioxosulfate
IUPAC
Bisulfite
KEGG_COMPOUND
HSO3(-)
IUPAC
HSO3-
KEGG_COMPOUND
Hydrogen sulfite
KEGG_COMPOUND
[SO2(OH)](-)
IUPAC
bisulfite
ChemIDplus
bisulphite
ChemIDplus
hydrogen sulfite(1-)
ChemIDplus
hydrosulfite anion
ChemIDplus
The 7H-tautomer of purine.
0
C5H4N4
InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
KDCGOANMDULRCW-UHFFFAOYSA-N
120.11222
120.04360
c1ncc2[nH]cnc2n1
CHEBI:14968
CHEBI:8639
Beilstein:3200
Gmelin:601779
HMDB:HMDB0001366
KEGG:C15587
Reaxys:3200
7H-purine
chebi_ontology
Purine
Purine base
CHEBI:17258
7H-purine
Beilstein:3200
Beilstein
Gmelin:601779
Gmelin
Reaxys:3200
Reaxys
7H-purine
IUPAC
Purine
KEGG_COMPOUND
Purine base
KEGG_COMPOUND
The L-enantiomer of phenylalanine.
0
C9H11NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
COLNVLDHVKWLRT-QMMMGPOBSA-N
165.18918
165.07898
N[C@@H](Cc1ccccc1)C(O)=O
CHEBI:13151
CHEBI:21370
CHEBI:44851
CHEBI:44885
CHEBI:45079
CHEBI:6282
Beilstein:1910408
CAS:63-91-2
DrugBank:DB00120
Drug_Central:2144
ECMDB:ECMDB00159
Gmelin:50837
HMDB:HMDB0000159
KEGG:C00079
KEGG:D00021
KNApSAcK:C00001386
MetaCyc:PHE
PDBeChem:PHE
PMID:13945318
PMID:16893175
PMID:17784858
PMID:21203787
PMID:21956539
PMID:22081386
PMID:22112574
PMID:22143120
PMID:22209218
PMID:22494897
PMID:23836015
PMID:24464217
PMID:24733517
PMID:24966042
Reaxys:1910408
Wikipedia:Phenylalanine
YMDB:YMDB00304
(2S)-2-amino-3-phenylpropanoic acid
L-Phenylalanine
L-phenylalanine
chebi_ontology
(S)-2-Amino-3-phenylpropionic acid
(S)-alpha-Amino-beta-phenylpropionic acid
3-phenyl-L-alanine
F
PHENYLALANINE
Phe
beta-phenyl-L-alanine
CHEBI:17295
L-phenylalanine
Beilstein:1910408
Beilstein
CAS:63-91-2
ChemIDplus
CAS:63-91-2
KEGG COMPOUND
CAS:63-91-2
NIST Chemistry WebBook
Drug_Central:2144
DrugCentral
Gmelin:50837
Gmelin
PMID:13945318
Europe PMC
PMID:16893175
Europe PMC
PMID:17784858
Europe PMC
PMID:21203787
Europe PMC
PMID:21956539
Europe PMC
PMID:22081386
Europe PMC
PMID:22112574
Europe PMC
PMID:22143120
Europe PMC
PMID:22209218
Europe PMC
PMID:22494897
Europe PMC
PMID:23836015
Europe PMC
PMID:24464217
Europe PMC
PMID:24733517
Europe PMC
PMID:24966042
Europe PMC
Reaxys:1910408
Reaxys
(2S)-2-amino-3-phenylpropanoic acid
IUPAC
L-Phenylalanine
KEGG_COMPOUND
L-phenylalanine
IUPAC
(S)-2-Amino-3-phenylpropionic acid
HMDB
(S)-alpha-Amino-beta-phenylpropionic acid
KEGG_COMPOUND
3-phenyl-L-alanine
NIST_Chemistry_WebBook
F
ChEBI
PHENYLALANINE
PDBeChem
Phe
ChEBI
beta-phenyl-L-alanine
NIST_Chemistry_WebBook
Sulfite is an inorganic anion, which is the conjugate base of hydrogen sulfite.
-2
O3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2
LSNNMFCWUKXFEE-UHFFFAOYSA-L
80.06420
79.95791
[O-]S([O-])=O
CHEBI:15139
CHEBI:45548
CAS:14265-45-3
Gmelin:1449
PDBeChem:SO3
sulfite
trioxidosulfate(2-)
trioxosulfate(2-)
trioxosulfate(IV)
chebi_ontology
SO3
SO3(2-)
SULFITE ION
[SO3](2-)
sulphite
CHEBI:17359
sulfite
CAS:14265-45-3
ChemIDplus
Gmelin:1449
Gmelin
sulfite
IUPAC
sulfite
UniProt
trioxidosulfate(2-)
IUPAC
trioxosulfate(2-)
IUPAC
trioxosulfate(IV)
IUPAC
SO3
ChEBI
SO3(2-)
IUPAC
SULFITE ION
PDBeChem
[SO3](2-)
IUPAC
sulphite
ChEBI
A straight-chain saturated fatty acid containing five carbon atoms.
0
C5H10O2
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
NQPDZGIKBAWPEJ-UHFFFAOYSA-N
102.13170
102.06808
CCCCC(O)=O
CHEBI:113448
CHEBI:27263
CHEBI:27264
CHEBI:43606
CHEBI:44803
CHEBI:7980
Beilstein:969454
CAS:109-52-4
DrugBank:DB02406
Gmelin:26714
HMDB:HMDB0000892
KEGG:C00803
KNApSAcK:C00001208
LIPID_MAPS_instance:LMFA01010005
PDBeChem:LEA
PDBeChem:PEI
PMID:20507156
PPDB:3130
Reaxys:969454
Wikipedia:Valeric_acid
Valeric acid
pentanoic acid
chebi_ontology
1-butanecarboxylic acid
CH3-[CH2]3-COOH
PENTANOIC ACID
Pentanoate
Pentanoic acid
Valerate
Valerianic acid
Valeriansaeure
n-BuCOOH
n-Pentanoate
n-Valeric acid
n-pentanoic acid
n-valeric acid
pentoic acid
propylacetic acid
valeric acid, normal
CHEBI:17418
valeric acid
Beilstein:969454
Beilstein
CAS:109-52-4
ChemIDplus
CAS:109-52-4
KEGG COMPOUND
CAS:109-52-4
NIST Chemistry WebBook
Gmelin:26714
Gmelin
LIPID_MAPS_instance:LMFA01010005
LIPID MAPS
PMID:20507156
Europe PMC
Reaxys:969454
Reaxys
Valeric acid
KEGG_COMPOUND
pentanoic acid
IUPAC
1-butanecarboxylic acid
ChemIDplus
1-butanecarboxylic acid
NIST_Chemistry_WebBook
CH3-[CH2]3-COOH
IUPAC
PENTANOIC ACID
PDBeChem
Pentanoate
KEGG_COMPOUND
Pentanoic acid
KEGG_COMPOUND
Valerate
KEGG_COMPOUND
Valerianic acid
KEGG_COMPOUND
Valeriansaeure
ChEBI
n-BuCOOH
ChEBI
n-Pentanoate
KEGG_COMPOUND
n-Valeric acid
KEGG_COMPOUND
n-pentanoic acid
ChemIDplus
n-valeric acid
ChemIDplus
pentoic acid
ChEBI
propylacetic acid
ChemIDplus
valeric acid, normal
ChemIDplus
A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
0
CHOR
29.01800
29.00274
[H]C([*])=O
CHEBI:13432
CHEBI:13753
CHEBI:13805
CHEBI:13806
CHEBI:22291
CHEBI:2554
CHEBI:8750
KEGG:C00071
Aldehyde
aldehyde
aldehydes
chebi_ontology
Aldehyd
RC(=O)H
RCHO
aldehido
aldehidos
aldehydes
aldehydum
an aldehyde
CHEBI:17478
aldehyde
Aldehyde
KEGG_COMPOUND
aldehyde
ChEBI
aldehyde
IUPAC
aldehydes
IUPAC
Aldehyd
ChEBI
RC(=O)H
IUPAC
RCHO
KEGG_COMPOUND
aldehido
ChEBI
aldehidos
ChEBI
aldehydes
ChEBI
aldehydum
ChEBI
an aldehyde
UniProt
The carbon oxoanion resulting from the removal of a proton from carbonic acid.
-1
CHO3
InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
BVKZGUZCCUSVTD-UHFFFAOYSA-M
61.01684
60.99312
OC([O-])=O
CHEBI:13363
CHEBI:22863
CHEBI:40961
CHEBI:5589
Beilstein:3903504
CAS:71-52-3
Gmelin:49249
HMDB:HMDB0000595
KEGG:C00288
MetaCyc:HCO3
PDBeChem:BCT
PMID:17215880
PMID:17505962
PMID:18439416
PMID:28732801
PMID:29150416
PMID:29460248
PMID:29466234
PMID:4208463
Wikipedia:Bicarbonate
Hydrogencarbonate
hydrogen(trioxidocarbonate)(1-)
hydrogencarbonate
hydrogencarbonate(1-)
hydrogentrioxocarbonate(1-)
hydrogentrioxocarbonate(IV)
hydroxidodioxidocarbonate(1-)
chebi_ontology
Acid carbonate
BICARBONATE ION
Bicarbonate
HCO3(-)
HCO3-
[CO2(OH)](-)
hydrogen carbonate
CHEBI:17544
hydrogencarbonate
Beilstein:3903504
Beilstein
CAS:71-52-3
ChemIDplus
Gmelin:49249
Gmelin
PMID:17215880
Europe PMC
PMID:17505962
Europe PMC
PMID:18439416
Europe PMC
PMID:28732801
Europe PMC
PMID:29150416
Europe PMC
PMID:29460248
Europe PMC
PMID:29466234
Europe PMC
PMID:4208463
Europe PMC
Hydrogencarbonate
KEGG_COMPOUND
hydrogen(trioxidocarbonate)(1-)
IUPAC
hydrogencarbonate
IUPAC
hydrogencarbonate
UniProt
hydrogencarbonate(1-)
IUPAC
hydrogentrioxocarbonate(1-)
IUPAC
hydrogentrioxocarbonate(IV)
IUPAC
hydroxidodioxidocarbonate(1-)
IUPAC
Acid carbonate
KEGG_COMPOUND
BICARBONATE ION
PDBeChem
Bicarbonate
KEGG_COMPOUND
HCO3(-)
IUPAC
HCO3-
KEGG_COMPOUND
[CO2(OH)](-)
IUPAC
hydrogen carbonate
PDBeChem
A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription.
0
C4H4N2O2
InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
ISAKRJDGNUQOIC-UHFFFAOYSA-N
112.08684
112.02728
O=c1cc[nH]c(=O)[nH]1
CHEBI:15288
CHEBI:27210
CHEBI:46375
CHEBI:9882
Beilstein:606623
CAS:66-22-8
DrugBank:DB03419
Gmelin:2896
HMDB:HMDB0000300
KEGG:C00106
KEGG:D00027
KNApSAcK:C00001513
MetaCyc:URACIL
PDBeChem:URA
PMID:11279060
PMID:12855717
PMID:15274295
PMID:16834123
PMID:17439666
PMID:18533995
PMID:18815805
PMID:19175333
PMID:22020693
PMID:22074393
PMID:22120518
PMID:22171528
PMID:22237209
PMID:22299724
PMID:22356544
PMID:22447672
PMID:22483865
PMID:22567906
PMID:22685418
PMID:3654008
Reaxys:606623
Wikipedia:Uracil
URACIL
Uracil
pyrimidine-2,4(1H,3H)-dione
uracil
chebi_ontology
2,4(1H,3H)-pyrimidinedione
2,4-Dioxopyrimidine
2,4-Pyrimidinedione
U
Ura
Urazil
CHEBI:17568
uracil
Beilstein:606623
Beilstein
CAS:66-22-8
ChemIDplus
CAS:66-22-8
KEGG COMPOUND
CAS:66-22-8
NIST Chemistry WebBook
Gmelin:2896
Gmelin
PMID:11279060
Europe PMC
PMID:12855717
Europe PMC
PMID:15274295
Europe PMC
PMID:16834123
Europe PMC
PMID:17439666
Europe PMC
PMID:18533995
Europe PMC
PMID:18815805
Europe PMC
PMID:19175333
Europe PMC
PMID:22020693
Europe PMC
PMID:22074393
Europe PMC
PMID:22120518
Europe PMC
PMID:22171528
Europe PMC
PMID:22237209
Europe PMC
PMID:22299724
Europe PMC
PMID:22356544
Europe PMC
PMID:22447672
Europe PMC
PMID:22483865
Europe PMC
PMID:22567906
Europe PMC
PMID:22685418
Europe PMC
PMID:3654008
Europe PMC
Reaxys:606623
Reaxys
URACIL
PDBeChem
Uracil
KEGG_COMPOUND
pyrimidine-2,4(1H,3H)-dione
IUPAC
uracil
UniProt
2,4(1H,3H)-pyrimidinedione
NIST_Chemistry_WebBook
2,4-Dioxopyrimidine
HMDB
2,4-Pyrimidinedione
HMDB
U
ChEBI
Ura
CBN
Urazil
ChEBI
The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.
0
C7H8
InChI=1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
YXFVVABEGXRONW-UHFFFAOYSA-N
92.13842
92.06260
Cc1ccccc1
CHEBI:15248
CHEBI:27022
CHEBI:44023
CHEBI:9624
Beilstein:635760
CAS:108-88-3
DrugBank:DB01900
Gmelin:2456
KEGG:C01455
PDBeChem:MBN
PMID:11182169
PMID:11314682
PMID:11846266
PMID:11991009
PMID:12062755
PMID:12213539
PMID:12237258
PMID:12784113
PMID:12876426
PMID:14512097
PMID:14559343
PMID:14605898
PMID:15015825
PMID:15019953
PMID:15119846
PMID:15193425
PMID:15542760
PMID:15567510
PMID:15695158
PMID:15796064
PMID:16316648
PMID:16348226
PMID:16601996
PMID:17145141
PMID:17175136
PMID:17497535
PMID:17725881
PMID:18397809
PMID:18832024
PMID:19261054
PMID:19384711
PMID:19429395
PMID:19635754
PMID:19765629
PMID:19825861
PMID:19928203
PMID:19969016
PMID:20347282
PMID:20837561
PMID:21430649
PMID:21655021
PMID:21731073
PMID:21802510
PMID:21840036
Reaxys:635760
UM-BBD_compID:c0114
Wikipedia:Toluene
TOLUENE
Toluene
toluene
chebi_ontology
Toluen
Toluol
methylbenzene
phenylmethane
CHEBI:17578
toluene
PMID:12237258
Europe PMC
PMID:12784113
Europe PMC
PMID:12876426
Europe PMC
PMID:14512097
Europe PMC
PMID:14559343
Europe PMC
PMID:14605898
Europe PMC
PMID:15015825
Europe PMC
PMID:15019953
Europe PMC
PMID:15119846
Europe PMC
PMID:15193425
Europe PMC
PMID:15542760
Europe PMC
PMID:15567510
Europe PMC
PMID:15695158
Europe PMC
PMID:15796064
Europe PMC
PMID:16316648
Europe PMC
PMID:16348226
Europe PMC
PMID:16601996
Europe PMC
PMID:17145141
Europe PMC
PMID:17175136
Europe PMC
PMID:17497535
Europe PMC
PMID:17725881
Europe PMC
PMID:18397809
Europe PMC
PMID:18832024
Europe PMC
PMID:19261054
Europe PMC
PMID:19384711
Europe PMC
PMID:19429395
Europe PMC
PMID:19635754
Europe PMC
PMID:19765629
Europe PMC
PMID:19825861
Europe PMC
PMID:19928203
Europe PMC
PMID:19969016
Europe PMC
PMID:20347282
Europe PMC
PMID:20837561
Europe PMC
PMID:21430649
Europe PMC
PMID:21655021
Europe PMC
PMID:21731073
Europe PMC
PMID:21802510
Europe PMC
PMID:21840036
Europe PMC
Reaxys:635760
Reaxys
UM-BBD_compID:c0114
UM-BBD
TOLUENE
PDBeChem
Toluene
KEGG_COMPOUND
toluene
ChEBI
toluene
IUPAC
toluene
UniProt
Toluen
NIST_Chemistry_WebBook
Toluol
NIST_Chemistry_WebBook
methylbenzene
PDBeChem
phenylmethane
ChemIDplus
Beilstein:635760
Beilstein
CAS:108-88-3
ChemIDplus
CAS:108-88-3
KEGG COMPOUND
CAS:108-88-3
NIST Chemistry WebBook
Gmelin:2456
Gmelin
PMID:11182169
Europe PMC
PMID:11314682
Europe PMC
PMID:11846266
Europe PMC
PMID:11991009
Europe PMC
PMID:12062755
Europe PMC
PMID:12213539
Europe PMC
A straight chain alkane composed of 8 carbon atoms.
0
C8H18
InChI=1S/C8H18/c1-3-5-7-8-6-4-2/h3-8H2,1-2H3
TVMXDCGIABBOFY-UHFFFAOYSA-N
114.22852
114.14085
CCCCCCCC
CHEBI:14680
CHEBI:25465
CHEBI:25645
CHEBI:44621
CHEBI:7723
Beilstein:1696875
CAS:111-65-9
DrugBank:DB02440
Gmelin:82412
HMDB:HMDB0001485
KEGG:C01387
LIPID_MAPS_instance:LMFA11000002
MetaCyc:CPD-148
PDBeChem:OCT
PMID:11255151
PMID:24354334
Reaxys:1696875
UM-BBD_compID:c0044
Wikipedia:Octane
Octane
octane
chebi_ontology
CH3-[CH2]6-CH3
N-OCTANE
Oktan
n-Octane
n-Oktan
CHEBI:17590
octane
Beilstein:1696875
Beilstein
CAS:111-65-9
ChemIDplus
CAS:111-65-9
KEGG COMPOUND
CAS:111-65-9
NIST Chemistry WebBook
Gmelin:82412
Gmelin
LIPID_MAPS_instance:LMFA11000002
LIPID MAPS
PMID:11255151
Europe PMC
PMID:24354334
Europe PMC
Reaxys:1696875
Reaxys
UM-BBD_compID:c0044
UM-BBD
Octane
KEGG_COMPOUND
octane
IUPAC
octane
UniProt
CH3-[CH2]6-CH3
IUPAC
N-OCTANE
PDBeChem
Oktan
NIST_Chemistry_WebBook
n-Octane
KEGG_COMPOUND
n-Oktan
ChEBI
A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
0
C6H6O2
InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
QIGBRXMKCJKVMJ-UHFFFAOYSA-N
110.11064
110.03678
Oc1ccc(O)cc1
CHEBI:14416
CHEBI:24645
CHEBI:5793
Beilstein:605970
CAS:123-31-9
Drug_Central:3282
Gmelin:2742
HMDB:HMDB0002434
KEGG:C00530
KEGG:C15603
KEGG:D00073
KNApSAcK:C00002656
MetaCyc:HYDROQUINONE
PMID:11170505
PMID:12213471
PMID:1395635
PMID:15618234
PMID:15894107
PMID:1899343
PMID:19148301
PMID:24407054
PMID:24858384
PMID:25586344
PPDB:1503
Reaxys:605970
UM-BBD_compID:c0091
Wikipedia:Hydroquinone
Hydroquinone
benzene-1,4-diol
hydroquinone
chebi_ontology
1,4-Benzenediol
1,4-Dihydroxybenzene
4-Hydroxyphenol
Benzene-1,4-diol
Eldoquin
Quinol
p-Benzenediol
p-Hydroquinone
p-hydroxyphenol
CHEBI:17594
hydroquinone
Beilstein:605970
Beilstein
CAS:123-31-9
ChemIDplus
CAS:123-31-9
KEGG COMPOUND
CAS:123-31-9
NIST Chemistry WebBook
Drug_Central:3282
DrugCentral
Gmelin:2742
Gmelin
PMID:11170505
Europe PMC
PMID:12213471
Europe PMC
PMID:1395635
Europe PMC
PMID:15618234
Europe PMC
PMID:15894107
Europe PMC
PMID:1899343
Europe PMC
PMID:19148301
Europe PMC
PMID:24407054
Europe PMC
PMID:24858384
Europe PMC
PMID:25586344
Europe PMC
Reaxys:605970
Reaxys
UM-BBD_compID:c0091
UM-BBD
Hydroquinone
KEGG_COMPOUND
benzene-1,4-diol
IUPAC
hydroquinone
UniProt
1,4-Benzenediol
KEGG_COMPOUND
1,4-Dihydroxybenzene
KEGG_COMPOUND
4-Hydroxyphenol
KEGG_COMPOUND
Benzene-1,4-diol
KEGG_COMPOUND
Eldoquin
ChemIDplus
Quinol
KEGG_COMPOUND
p-Benzenediol
KEGG_COMPOUND
p-Hydroquinone
KEGG_COMPOUND
p-hydroxyphenol
NIST_Chemistry_WebBook
0
C6H6O2
110.111
110.03678
CHEBI:13878
CHEBI:3027
CAS:12385-08-9
KEGG:C01785
Benzenediol
benzenediol
chebi_ontology
dihydroxybenzene
CHEBI:17701
benzenediol
CAS:12385-08-9
ChemIDplus
CAS:12385-08-9
KEGG COMPOUND
Benzenediol
KEGG_COMPOUND
benzenediol
IUPAC
dihydroxybenzene
ChEBI
A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
0
ClH
HCl
InChI=1S/ClH/h1H
VEXZGXHMUGYJMC-UHFFFAOYSA-N
36.46064
35.97668
Cl[H]
CHEBI:13364
CHEBI:24635
CHEBI:5590
CAS:7647-01-0
Drug_Central:4568
Gmelin:322
HMDB:HMDB0002306
KEGG:C01327
KEGG:D02057
MetaCyc:HCL
PMID:15823700
PMID:17492841
PMID:22804993
Reaxys:1098214
Wikipedia:HCl
Wikipedia:Hydrochloric_acid
Hydrogen chloride
chlorane
chloridohydrogen
hydrogen chloride
chebi_ontology
Chlorwasserstoff
HCl
Hydrochloride
Hydrogenchlorid
Wasserstoffchlorid
[HCl]
chlorure d'hydrogene
cloruro de hidrogeno
hydrochloric acid
CHEBI:17883
hydrogen chloride
CAS:7647-01-0
ChemIDplus
CAS:7647-01-0
KEGG COMPOUND
CAS:7647-01-0
NIST Chemistry WebBook
Drug_Central:4568
DrugCentral
Gmelin:322
Gmelin
PMID:15823700
Europe PMC
PMID:17492841
Europe PMC
PMID:22804993
Europe PMC
Reaxys:1098214
Reaxys
Hydrogen chloride
KEGG_COMPOUND
chlorane
IUPAC
chloridohydrogen
IUPAC
hydrogen chloride
IUPAC
Chlorwasserstoff
ChEBI
HCl
KEGG_COMPOUND
Hydrochloride
KEGG_COMPOUND
Hydrogenchlorid
ChEBI
Wasserstoffchlorid
ChEBI
[HCl]
IUPAC
chlorure d'hydrogene
ChEBI
cloruro de hidrogeno
ChEBI
hydrochloric acid
ChemIDplus
A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
CHEBI:14202
CHEBI:4697
KEGG:C01351
Donor
chebi_ontology
Donator
donneur
CHEBI:17891
donor
Donor
KEGG_COMPOUND
Donator
ChEBI
donneur
ChEBI
A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.
0
C3H7NO2
InChI=1S/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)
JOYRKODLDBILNP-UHFFFAOYSA-N
89.09322
89.04768
CCOC(N)=O
CHEBI:15295
CHEBI:27225
CHEBI:9892
CAS:51-79-6
DrugBank:DB04827
HMDB:HMDB0031219
KEGG:C01537
LINCS:LSM-37020
PMID:15790490
PMID:24386880
Reaxys:635810
Wikipedia:Ethyl_carbamate
Urethane
ethyl carbamate
urethane
FlyBase miscellaneous CV
chebi_ontology
Ethyl carbamate
carbamic acid ethyl ester
CHEBI:17967
urethane
CAS:51-79-6
KEGG COMPOUND
PMID:15790490
Europe PMC
PMID:24386880
Europe PMC
Reaxys:635810
Reaxys
Urethane
KEGG_COMPOUND
ethyl carbamate
IUPAC
urethane
UniProt
Ethyl carbamate
KEGG_COMPOUND
carbamic acid ethyl ester
ChEBI
A halide anion formed when chlorine picks up an electron to form an an anion.
-1
Cl
InChI=1S/ClH/h1H/p-1
VEXZGXHMUGYJMC-UHFFFAOYSA-M
35.45270
34.96940
[Cl-]
CHEBI:13291
CHEBI:13970
CHEBI:3616
CHEBI:3731
CHEBI:48804
Beilstein:3587171
CAS:16887-00-6
Gmelin:14910
KEGG:C00115
KEGG:C00698
PDBeChem:CL
UM-BBD_compID:c0884
Chloride
chloride
chloride(1-)
chebi_ontology
CHLORIDE ION
Chloride ion
Chloride(1-)
Chlorine anion
Cl(-)
Cl-
CHEBI:17996
chloride
Beilstein:3587171
Beilstein
CAS:16887-00-6
ChemIDplus
CAS:16887-00-6
KEGG COMPOUND
CAS:16887-00-6
NIST Chemistry WebBook
Gmelin:14910
Gmelin
UM-BBD_compID:c0884
UM-BBD
Chloride
KEGG_COMPOUND
chloride
IUPAC
chloride
UniProt
chloride(1-)
IUPAC
CHLORIDE ION
PDBeChem
Chloride ion
KEGG_COMPOUND
Chloride(1-)
ChemIDplus
Chlorine anion
NIST_Chemistry_WebBook
Cl(-)
IUPAC
Cl-
KEGG_COMPOUND
'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
CHEBI:14517
CHEBI:25054
CHEBI:6486
KEGG:C01356
Lipid
lipids
chebi_ontology
CHEBI:18059
lipid
Lipid
KEGG_COMPOUND
lipids
IUPAC
0
HX
1.008
1.00783
[F,Cl,Br,I]
CHEBI:13368
CHEBI:37140
CHEBI:5599
hydrogen halide
hydrogen halides
chebi_ontology
HX
hydrogen halides
CHEBI:18140
hydrogen halide
hydrogen halide
IUPAC
hydrogen halides
IUPAC
HX
UniProt
hydrogen halides
ChEBI
An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.
0
C5H9NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)
WHUUTDBJXJRKMK-UHFFFAOYSA-N
147.12930
147.05316
NC(CCC(O)=O)C(O)=O
CHEBI:24314
CHEBI:5431
Beilstein:1723799
CAS:617-65-2
Gmelin:101971
KEGG:C00302
KEGG:D04341
KNApSAcK:C00001358
KNApSAcK:C00019577
PMID:15739367
PMID:17190852
PMID:24616376
PMID:24984001
Reaxys:1723799
Wikipedia:Glutamic_acid
2-aminopentanedioic acid
Glutamic acid
glutamic acid
chebi_ontology
2-Aminoglutaric acid
DL-Glutamic acid
DL-Glutaminic acid
E
Glu
Glutamate
Glutaminic acid
Glutaminsaeure
CHEBI:18237
glutamic acid
Beilstein:1723799
Beilstein
CAS:617-65-2
ChemIDplus
CAS:617-65-2
KEGG COMPOUND
CAS:617-65-2
NIST Chemistry WebBook
Gmelin:101971
Gmelin
PMID:15739367
Europe PMC
PMID:17190852
Europe PMC
PMID:24616376
Europe PMC
PMID:24984001
Europe PMC
Reaxys:1723799
Reaxys
2-aminopentanedioic acid
IUPAC
Glutamic acid
KEGG_COMPOUND
glutamic acid
IUPAC
2-Aminoglutaric acid
KEGG_COMPOUND
DL-Glutamic acid
KEGG_DRUG
DL-Glutaminic acid
KEGG_COMPOUND
E
ChEBI
Glu
ChEBI
Glutamate
KEGG_COMPOUND
Glutaminic acid
KEGG_COMPOUND
Glutaminsaeure
ChEBI
Any nucleoside where the sugar component is D-ribose.
0
C5H9O4R
133.123
133.05008
OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O
CHEBI:13014
CHEBI:13015
CHEBI:13685
CHEBI:21085
CHEBI:26560
CHEBI:4240
CHEBI:8844
KEGG:C00911
Ribonucleoside
chebi_ontology
a ribonucleoside
ribonucleosides
CHEBI:18254
ribonucleoside
Ribonucleoside
KEGG_COMPOUND
a ribonucleoside
UniProt
ribonucleosides
ChEBI
That part of DNA or RNA that may be involved in pairing.
CHEBI:13873
CHEBI:25598
CHEBI:2995
KEGG:C00701
Wikipedia:Nucleobase
chebi_ontology
Base
nucleobases
CHEBI:18282
nucleobase
Base
KEGG_COMPOUND
nucleobases
ChEBI
An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
0
CH3R
15.035
15.02348
C[*]
CHEBI:13435
CHEBI:22317
CHEBI:2576
KEGG:C01371
Alkane
alkane
alkanes
chebi_ontology
Alkan
RH
alcane
alcanes
alcano
alcanos
an alkane
CHEBI:18310
alkane
Alkane
KEGG_COMPOUND
alkane
IUPAC
alkanes
IUPAC
Alkan
ChEBI
RH
KEGG_COMPOUND
alcane
IUPAC
alcanes
IUPAC
alcano
IUPAC
alcanos
IUPAC
an alkane
UniProt
A phosphate ion that is the conjugate base of hydrogenphosphate.
-3
O4P
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
NBIIXXVUZAFLBC-UHFFFAOYSA-K
94.97136
94.95507
[O-]P([O-])([O-])=O
CHEBI:14791
CHEBI:45024
CHEBI:7793
Beilstein:3903772
CAS:14265-44-2
Gmelin:1997
KEGG:C00009
PDBeChem:PO4
Reaxys:3903772
phosphate
tetraoxidophosphate(3-)
tetraoxophosphate(3-)
tetraoxophosphate(V)
chebi_ontology
Orthophosphate
PHOSPHATE ION
PO4(3-)
Phosphate
[PO4](3-)
CHEBI:18367
phosphate(3-)
Beilstein:3903772
Beilstein
CAS:14265-44-2
ChemIDplus
CAS:14265-44-2
KEGG COMPOUND
Gmelin:1997
Gmelin
PDBeChem:PO4
ChEBI
Reaxys:3903772
Reaxys
phosphate
IUPAC
tetraoxidophosphate(3-)
IUPAC
tetraoxophosphate(3-)
IUPAC
tetraoxophosphate(V)
IUPAC
Orthophosphate
KEGG_COMPOUND
PHOSPHATE ION
PDBeChem
PO4(3-)
IUPAC
Phosphate
KEGG_COMPOUND
[PO4](3-)
IUPAC
0
C10H9NO4S
InChI=1S/C10H9NO4S/c11-10-7-4-2-1-3-6(7)9(5-8(10)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)
RXCMFQDTWCCLBL-UHFFFAOYSA-N
239.24880
239.02523
Nc1c(O)cc(c2ccccc12)S(O)(=O)=O
Beilstein:2697469
CAS:116-63-2
Gmelin:241697
4-amino-3-hydroxynaphthalene-1-sulfonic acid
FlyBase miscellaneous CV
chebi_ontology
1-amino-2-naphthol-4-sulfonic acid
1-amino-4-sulfo-2-naphthol
4-amino-3-hydroxynaphthalene-1-sulphonic acid
CHEBI:19024
4-amino-3-hydroxynaphthalene-1-sulfonic acid
Beilstein:2697469
Beilstein
CAS:116-63-2
ChemIDplus
CAS:116-63-2
NIST Chemistry WebBook
Gmelin:241697
Gmelin
4-amino-3-hydroxynaphthalene-1-sulfonic acid
IUPAC
1-amino-2-naphthol-4-sulfonic acid
ChemIDplus
1-amino-4-sulfo-2-naphthol
ChemIDplus
4-amino-3-hydroxynaphthalene-1-sulphonic acid
ChemIDplus
A haloalkane that is bromoethane substituted by chlorine at position 2.
0
C2H4BrCl
InChI=1S/C2H4BrCl/c3-1-2-4/h1-2H2
IBYHHJPAARCAIE-UHFFFAOYSA-N
143.40986
141.91849
ClCCBr
Beilstein:605265
CAS:107-04-0
Gmelin:984479
PMID:6357525
PMID:8200089
Reaxys:605265
1-bromo-2-chloroethane
FlyBase miscellaneous CV
chebi_ontology
1,2-bromochloroethane
1,2-chlorobromoethane
2-bromo-1-chloroethane
2-bromoethyl chloride
2-chloroethyl bromide
beta-chloroethyl bromide
ethylene chlorobromide
CHEBI:19032
1-bromo-2-chloroethane
Beilstein:605265
Beilstein
CAS:107-04-0
ChemIDplus
CAS:107-04-0
NIST Chemistry WebBook
Gmelin:984479
Gmelin
PMID:6357525
Europe PMC
PMID:8200089
Europe PMC
Reaxys:605265
Reaxys
1-bromo-2-chloroethane
IUPAC
1,2-bromochloroethane
NIST_Chemistry_WebBook
1,2-chlorobromoethane
ChemIDplus
2-bromo-1-chloroethane
ChemIDplus
2-bromoethyl chloride
NIST_Chemistry_WebBook
2-chloroethyl bromide
NIST_Chemistry_WebBook
beta-chloroethyl bromide
NIST_Chemistry_WebBook
ethylene chlorobromide
ChemIDplus
A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups.
0
C10H10N2O2
InChI=1S/C10H10N2O2/c13-9-6-8(12-3-4-12)10(14)5-7(9)11-1-2-11/h5-6H,1-4H2
RCWJMKCTHJPXJV-UHFFFAOYSA-N
190.19868
190.07423
O=C1C=C(N2CC2)C(=O)C=C1N1CC1
Beilstein:169182
CAS:526-62-5
PMID:10373575
PMID:10978162
PMID:11211879
PMID:13415397
PMID:17094478
PMID:1751490
PMID:8137269
PMID:8461296
PMID:9690517
Reaxys:169182
2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
FlyBase miscellaneous CV
chebi_ontology
2,5,-bis(ethyleneimine)-1,4-benzoquinone
2,5,-bisethylene-imine-1,4-benzoquinone
2,5-Bisaethyleniminobenzochinon-1,4
2,5-bis(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione
2,5-bis(1-aziridinyl)-p-benzoquinone
2,5-bis(1-aziridynyl)benzoquinone
2,5-bis(aziridino)-1,4-benzoquinone
2,5-bis(aziridino)benzoquinone
2,5-bis(ethyleneimino)-1,4-benzoquinone
2,5-bis-ethyleniminobenzoquinone
2,5-bisethyleneiminebenzoquinone
2,5-di(ethyleneimino)-1,4-benzoquinone
2,5-diaziridinyl-1,4-benzoquinone
3,6-diaziridinyl-1,4-benzoquinone
DZQ
TW 13
ethylenimine quinone
CHEBI:19363
2,5-bis(aziridin-1-yl)-1,4-benzoquinone
Beilstein:169182
Beilstein
CAS:526-62-5
ChemIDplus
PMID:10373575
Europe PMC
PMID:10978162
Europe PMC
PMID:11211879
Europe PMC
PMID:13415397
Europe PMC
PMID:17094478
Europe PMC
PMID:1751490
Europe PMC
PMID:8137269
Europe PMC
PMID:8461296
Europe PMC
PMID:9690517
Europe PMC
Reaxys:169182
Reaxys
2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione
IUPAC
2,5,-bis(ethyleneimine)-1,4-benzoquinone
ChEBI
2,5,-bisethylene-imine-1,4-benzoquinone
ChEBI
2,5-Bisaethyleniminobenzochinon-1,4
ChEBI
2,5-bis(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione
ChemIDplus
2,5-bis(1-aziridinyl)-p-benzoquinone
ChemIDplus
2,5-bis(1-aziridynyl)benzoquinone
ChemIDplus
2,5-bis(aziridino)-1,4-benzoquinone
ChemIDplus
2,5-bis(aziridino)benzoquinone
ChemIDplus
2,5-bis(ethyleneimino)-1,4-benzoquinone
ChemIDplus
2,5-bis-ethyleniminobenzoquinone
ChemIDplus
2,5-bisethyleneiminebenzoquinone
ChemIDplus
2,5-di(ethyleneimino)-1,4-benzoquinone
ChemIDplus
2,5-diaziridinyl-1,4-benzoquinone
ChemIDplus
3,6-diaziridinyl-1,4-benzoquinone
ChEBI
DZQ
ChEBI
TW 13
ChemIDplus
ethylenimine quinone
ChemIDplus
FlyBase miscellaneous CV
chebi_ontology
CHEBI:19508
2-chloroethyl methanesulfonate
FlyBase miscellaneous CV
chebi_ontology
CHEBI:19579
2-fluoroethyl methanesulfonate
A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.
0
C4H3BrN2O2
InChI=1S/C4H3BrN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
LQLQRFGHAALLLE-UHFFFAOYSA-N
190.98300
189.93779
Brc1c[nH]c(=O)[nH]c1=O
Beilstein:127176
CAS:51-20-7
Gmelin:486432
PMID:14522043
PMID:28166217
PMID:28320905
PMID:3950402
5-bromopyrimidine-2,4(1H,3H)-dione
FlyBase miscellaneous CV
chebi_ontology
1,2,3,4-tetrahydro-5-bromo-2,4-pyrimidinedione
5-BU
5-BrU
5-bromo-2,4(1H,3H)-pyrimidinedione
bromouracil
CHEBI:20552
5-bromouracil
Beilstein:127176
Beilstein
CAS:51-20-7
ChemIDplus
CAS:51-20-7
NIST Chemistry WebBook
Gmelin:486432
Gmelin
PMID:14522043
Europe PMC
PMID:28166217
Europe PMC
PMID:28320905
Europe PMC
PMID:3950402
Europe PMC
5-bromopyrimidine-2,4(1H,3H)-dione
IUPAC
1,2,3,4-tetrahydro-5-bromo-2,4-pyrimidinedione
NIST_Chemistry_WebBook
5-BU
ChemIDplus
5-BrU
ChemIDplus
5-bromo-2,4(1H,3H)-pyrimidinedione
NIST_Chemistry_WebBook
bromouracil
ChemIDplus
A uridine having a bromo substituent at the 5-position.
0
C9H11BrN2O6
InChI=1S/C9H11BrN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
AGFIRQJZCNVMCW-UAKXSSHOSA-N
323.09752
321.98005
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O
Beilstein:33664
CAS:957-75-5
Gmelin:723432
PMID:3950402
5-bromouridine
FlyBase miscellaneous CV
chebi_ontology
1-beta-ribofuranosyl-5-bromo-uracil
5-bromo-1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione
BrU
CHEBI:20553
5-bromouridine
Beilstein:33664
Beilstein
CAS:957-75-5
ChemIDplus
Gmelin:723432
Gmelin
PMID:3950402
Europe PMC
5-bromouridine
ChEBI
5-bromouridine
IUPAC
1-beta-ribofuranosyl-5-bromo-uracil
ChemIDplus
5-bromo-1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione
ChEBI
BrU
ChEBI
Any aminopurine having the amino substituent at the 2-position.
2-aminopurines
chebi_ontology
CHEBI:20702
2-aminopurines
2-aminopurines
ChEBI
A member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively.
0
C20H15Br
InChI=1S/C20H15Br/c1-13-15-7-4-5-9-17(15)19(12-21)18-11-10-14-6-2-3-8-16(14)20(13)18/h2-11H,12H2,1H3
IBWBDNBSIFGSLW-UHFFFAOYSA-N
335.23710
334.03571
Cc1c2ccccc2c(CBr)c2ccc3ccccc3c12
Beilstein:2056479
CAS:16238-56-5
PMID:10838135
PMID:3114533
PMID:8625451
Reaxys:2056479
7-(bromomethyl)-12-methyltetraphene
FlyBase miscellaneous CV
chebi_ontology
7-BrMe-12-MeBA
7-bromomethyl-12-methylbenz[a]anthracene
7-bromomethyl-12-methylbenzanthracene
CHEBI:20787
7-bromomethyl-12-methyltetraphene
Beilstein:2056479
Beilstein
CAS:16238-56-5
ChemIDplus
PMID:10838135
Europe PMC
PMID:3114533
Europe PMC
PMID:8625451
Europe PMC
Reaxys:2056479
Reaxys
7-(bromomethyl)-12-methyltetraphene
IUPAC
7-BrMe-12-MeBA
ChEBI
7-bromomethyl-12-methylbenz[a]anthracene
ChemIDplus
7-bromomethyl-12-methylbenzanthracene
ChemIDplus
0
C21H27Cl4N3O
InChI=1S/C21H25Cl2N3O.2ClH/c1-3-26(12-9-22)11-4-10-24-21-17-7-5-15(23)13-20(17)25-19-8-6-16(27-2)14-18(19)21;;/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,24,25);2*1H
PWGOWIIEVDAYTC-UHFFFAOYSA-N
479.26950
477.09082
Cl[H].Cl[H].CCN(CCCl)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12
CAS:146-59-8
N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine dihydrochloride
FlyBase miscellaneous CV
chebi_ontology
ICR 170
N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-N-ethyl-1,3-propanediamine dihydrochloride
acridine mustard
CHEBI:21183
ICR-170
CAS:146-59-8
ChemIDplus
N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine dihydrochloride
IUPAC
ICR 170
ChemIDplus
N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-N-ethyl-1,3-propanediamine dihydrochloride
ChemIDplus
acridine mustard
ChemIDplus
0
C30H31ClN6
InChI=1S/C30H31N6.ClH/c1-5-35(6-2)26-17-19-28-30(21-26)36(25-10-8-7-9-11-25)29-20-23(14-18-27(29)31-28)33-32-22-12-15-24(16-13-22)34(3)4;/h7-21H,5-6H2,1-4H3;1H/q+1;/p-1
XXACTDWGHQXLGW-UHFFFAOYSA-M
511.06028
510.22987
[Cl-].CCN(CC)c1ccc2nc3ccc(cc3[n+](-c3ccccc3)c2c1)\N=N\c1ccc(cc1)N(C)C
Beilstein:9748061
CAS:2869-83-2
Patent:US2882209
3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium chloride
FlyBase miscellaneous CV
chebi_ontology
3-(diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride
3-(diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride
Janus Green B
Janus Green V
CHEBI:21184
Janus Green B chloride
Beilstein:9748061
Beilstein
CAS:2869-83-2
ChemIDplus
3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium chloride
IUPAC
3-(diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride
ChemIDplus
3-(diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride
ChemIDplus
Janus Green B
ChemIDplus
Janus Green V
ChemIDplus
Any N-acylamino acid having L-configuration.
chebi_ontology
CHEBI:21644
N-acyl-L-amino acid
A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.
glycosylamine
chebi_ontology
N-glycoside
N-glycosides
N-glycosyl compounds
glycosylamines
CHEBI:21731
N-glycosyl compound
glycosylamine
IUPAC
N-glycoside
ChEBI
N-glycosides
ChEBI
N-glycosyl compounds
ChEBI
glycosylamines
IUPAC
An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position
0
C2H5N5O3
InChI=1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4)
VZUNGTLZRAYYDE-UHFFFAOYSA-N
147.09280
147.03924
CN(N=O)C(=N)N[N+]([O-])=O
CHEBI:34872
Beilstein:1779490
CAS:70-25-7
KEGG:C14592
1-methyl-3-nitro-1-nitrosoguanidine
N-Methyl-N'-nitro-N-nitrosoguanidine
FlyBase miscellaneous CV
chebi_ontology
1-Methyl-1-nitroso-3-nitroguanidine
1-Methyl-3-nitro-1-nitrosoguanidine
1-Nitroso-3-nitro-1-methylguanidine
MNG
MNNG
Methylnitronitrosoguanidine
N'-Nitro-N-nitroso-N-methylguanidine
N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide
N-Methyl-N-nitroso-N'-nitroguanidine
N-Methyl-N-nitrosonitroguanidin
N-Nitroso-N-methyl-N'-nitroguanidine
CHEBI:21759
N-methyl-N'-nitro-N-nitrosoguanidine
Beilstein:1779490
Beilstein
CAS:70-25-7
ChemIDplus
CAS:70-25-7
KEGG COMPOUND
CAS:70-25-7
NIST Chemistry WebBook
1-methyl-3-nitro-1-nitrosoguanidine
IUPAC
N-Methyl-N'-nitro-N-nitrosoguanidine
KEGG_COMPOUND
1-Methyl-1-nitroso-3-nitroguanidine
ChemIDplus
1-Methyl-3-nitro-1-nitrosoguanidine
KEGG_COMPOUND
1-Nitroso-3-nitro-1-methylguanidine
ChemIDplus
MNG
ChemIDplus
MNNG
ChemIDplus
MNNG
KEGG_COMPOUND
Methylnitronitrosoguanidine
KEGG_COMPOUND
N'-Nitro-N-nitroso-N-methylguanidine
ChemIDplus
N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide
NIST_Chemistry_WebBook
N-Methyl-N-nitroso-N'-nitroguanidine
ChEBI
N-Methyl-N-nitroso-N'-nitroguanidine
ChemIDplus
N-Methyl-N-nitrosonitroguanidin
ChEBI
N-Nitroso-N-methyl-N'-nitroguanidine
ChemIDplus
FlyBase miscellaneous CV
chebi_ontology
CHEBI:22025
S-2-chloroethylcysteine
An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H).
CHEBI:35813
sulfoxide
chebi_ontology
S-oxides
sulfoxides
CHEBI:22063
sulfoxide
sulfoxide
ChEBI
S-oxides
ChEBI
sulfoxides
ChEBI
Compounds with the general formula RNHC(=O)CH3.
chebi_ontology
CHEBI:22160
acetamides
chebi_ontology
CHEBI:22213
acridines
An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.
acyl group
alkanoyl
chebi_ontology
acyl groups
alkanoyl group
groupe acyle
CHEBI:22221
acyl group
acyl group
IUPAC
alkanoyl
IUPAC
acyl groups
ChEBI
alkanoyl group
ChEBI
groupe acyle
IUPAC
alkali metals
chebi_ontology
Alkalimetall
Alkalimetalle
alkali metal
metal alcalin
metal alcalino
metales alcalinos
metaux alcalins
CHEBI:22314
alkali metal atom
alkali metals
IUPAC
Alkalimetall
ChEBI
Alkalimetalle
ChEBI
alkali metal
ChEBI
metal alcalin
ChEBI
metal alcalino
ChEBI
metales alcalinos
ChEBI
metaux alcalins
ChEBI
Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.
Wikipedia:Alkaloid
Alkaloid
alkaloids
chebi_ontology
Alkaloide
alcaloide
alcaloides
CHEBI:22315
alkaloid
Alkaloid
ChEBI
alkaloids
IUPAC
Alkaloide
ChEBI
alcaloide
ChEBI
alcaloides
ChEBI
A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom.
alkyl group
alkyl groups
chebi_ontology
groupe alkyle
grupo alquilo
grupos alquilo
CHEBI:22323
alkyl group
alkyl group
IUPAC
alkyl groups
IUPAC
groupe alkyle
IUPAC
grupo alquilo
IUPAC
grupos alquilo
IUPAC
chebi_ontology
aliphatic thioether
aliphatic thioethers
CHEBI:22327
aliphatic sulfide
aliphatic thioether
ChEBI
aliphatic thioethers
ChEBI
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
chebi_ontology
CHEBI:22333
alkylating agent
chebi_ontology
aminobenzoates
CHEBI:22494
aminobenzoate
aminobenzoates
ChEBI
0
C19H20N8O5
InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1
TVZGACDUOSZQKY-LBPRGKRZSA-N
440.41302
440.15567
Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
Beilstein:69045
CAS:54-62-6
Drug_Central:21
PMID:18789931
4-aminofolic acid
N-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
FlyBase miscellaneous CV
chebi_ontology
4-amino-PGA
4-aminopteroylglutamic acid
N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
aminopterin
CHEBI:22526
4-aminofolic acid
Beilstein:69045
Beilstein
CAS:54-62-6
ChemIDplus
Drug_Central:21
DrugCentral
PMID:18789931
Europe PMC
4-aminofolic acid
ChemIDplus
N-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
IUPAC
4-amino-PGA
ChemIDplus
4-aminopteroylglutamic acid
ChemIDplus
N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
ChemIDplus
aminopterin
ChemIDplus
Any purine having at least one amino substituent.
chebi_ontology
aminopurines
CHEBI:22527
aminopurine
aminopurines
ChEBI
A monoatomic or polyatomic species having one or more elementary charges of the electron.
Anion
anion
chebi_ontology
Anionen
aniones
anions
CHEBI:22563
anion
Anion
ChEBI
anion
ChEBI
anion
IUPAC
Anionen
ChEBI
aniones
ChEBI
anions
IUPAC
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
chebi_ontology
antioxidants
antioxydant
antoxidant
CHEBI:22586
antioxidant
antioxidants
ChEBI
antioxydant
ChEBI
antoxidant
ChEBI
chebi_ontology
CHEBI:22681
aziridines
A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
KEGG:C00701
Base
base
chebi_ontology
Base1
Base2
Basen
Nucleobase
bases
CHEBI:22695
base
Base
ChEBI
base
ChEBI
base
IUPAC
Base1
KEGG_COMPOUND
Base2
KEGG_COMPOUND
Basen
ChEBI
Nucleobase
KEGG_COMPOUND
bases
ChEBI
Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
chebi_ontology
CHEBI:22712
benzenes
chebi_ontology
arenesulfonates
CHEBI:22713
arenesulfonate oxoanion
arenesulfonates
ChEBI
A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid.
chebi_ontology
benzoate anion
CHEBI:22718
benzoates
benzoate anion
ChEBI
Wikipedia:Benzopyran
chebi_ontology
benzopyrans
CHEBI:22727
benzopyran
benzopyrans
ChEBI
Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their C-substituted derivatives.
chebi_ontology
CHEBI:22729
benzoquinones
0
C7H7
91.13048
91.05478
benzyl
chebi_ontology
Bn
C6H5-CH2-
phenylalanine side-chain
phenylmethyl
CHEBI:22744
benzyl group
benzyl
IUPAC
Bn
ChEBI
C6H5-CH2-
IUPAC
phenylalanine side-chain
ChEBI
phenylmethyl
IUPAC
-3
BO3
InChI=1S/BO3/c2-1(3)4/q-3
BTBUEUYNUDRHOZ-UHFFFAOYSA-N
58.80920
58.99569
[O-]B([O-])[O-]
Gmelin:164057
borate
trioxidoborate(3-)
chebi_ontology
(BO3)3-
BO3(3-)
[BO3](3-)
borate ion
trioxoborate(3-) ion
trioxoborate(III) anion
CHEBI:22908
borate
Gmelin:164057
Gmelin
borate
IUPAC
trioxidoborate(3-)
IUPAC
(BO3)3-
ChEBI
BO3(3-)
IUPAC
[BO3](3-)
IUPAC
borate ion
ChEBI
trioxoborate(3-) ion
ChEBI
trioxoborate(III) anion
ChEBI
Any inorganic anion that is formally derived from boric acid. The term includes polymeric anions containing chains of BO3 structural units sharing one oxygen atom (e.g. di-, tri-, and tetraborates) as well as chains or rings sharing two oxygen atoms (e.g. metaborates).
Wikipedia:Borate
borate ion
chebi_ontology
borate anions
borate ions
CHEBI:22909
borate ion
borate ion
ChEBI
borate anions
ChEBI
borate ions
ChEBI
boron molecular entity
chebi_ontology
boron compounds
boron molecular entities
CHEBI:22916
boron molecular entity
boron molecular entity
ChEBI
boron compounds
ChEBI
boron molecular entities
ChEBI
A compound derived from a hydrocarbon by replacing a hydrogen atom with a bromine atom.
chebi_ontology
brominated hydrocarbons
bromohydrocarbons
CHEBI:22926
bromohydrocarbon
brominated hydrocarbons
ChEBI
bromohydrocarbons
ChEBI
0
Br
InChI=1S/Br
WKBOTKDWSSQWDR-UHFFFAOYSA-N
79.90400
78.91834
[Br]
WebElements:Br
bromine
chebi_ontology
35Br
Br
Brom
brome
bromine
bromo
bromum
CHEBI:22927
bromine atom
bromine
IUPAC
35Br
IUPAC
Br
ChEBI
Brom
ChEBI
brome
ChEBI
bromine
ChEBI
bromo
ChEBI
bromum
ChEBI
bromine molecular entity
chebi_ontology
bromine compounds
bromine molecular entities
CHEBI:22928
bromine molecular entity
bromine molecular entity
ChEBI
bromine compounds
ChEBI
bromine molecular entities
ChEBI
Any haloalkane that consists of an alkane substituted by at least one bromine atom.
chebi_ontology
alkyl bromide
alkyl bromides
bromoalkanes
CHEBI:22929
bromoalkane
alkyl bromide
ChEBI
alkyl bromides
ChEBI
bromoalkanes
ChEBI
A diol that is a butanediol or a derivative of a butanediol.
chebi_ontology
CHEBI:22944
butanediols
Any ester of carbamic acid or its N-substituted derivatives.
Wikipedia:Carbamate
chebi_ontology
carbamate esters
carbamates
CHEBI:23003
carbamate ester
carbamate esters
ChEBI
carbamates
ChEBI
The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid.
0
CH2NO
44.03272
44.01364
PMID:24168430
carbamoyl
chebi_ontology
-C(O)NH2
-CONH2
aminocarbonyl
carbamyl
carbamyl group
carboxamide
CHEBI:23004
carbamoyl group
PMID:24168430
Europe PMC
carbamoyl
IUPAC
-C(O)NH2
ChEBI
-CONH2
IUPAC
aminocarbonyl
IUPAC
carbamyl
ChEBI
carbamyl group
ChEBI
carboxamide
IUPAC
0
CO
28.01010
27.99491
carbonyl
carbonyl group
chebi_ontology
>C=O
CHEBI:23019
carbonyl group
carbonyl
IUPAC
carbonyl group
ChEBI
carbonyl group
UniProt
>C=O
IUPAC
A substance intended to sterilize any organism.
Wikipedia:Chemosterilant
chebi_ontology
chemosterilants
CHEBI:23092
chemosterilant
chemosterilants
ChEBI
chebi_ontology
chloride salts
chlorides
CHEBI:23114
chloride salt
chloride salts
ChEBI
chlorides
ChEBI
0
Cl
InChI=1S/Cl
ZAMOUSCENKQFHK-UHFFFAOYSA-N
35.45270
34.96885
[Cl]
WebElements:Cl
chlorine
chebi_ontology
17Cl
Chlor
Cl
chlore
chlorine
chlorum
cloro
CHEBI:23116
chlorine atom
chlorine
IUPAC
17Cl
IUPAC
Chlor
ChEBI
Cl
IUPAC
chlore
ChEBI
chlorine
ChEBI
chlorum
ChEBI
cloro
ChEBI
A halogen molecular entity containing one or more atoms of chlorine.
chebi_ontology
CHEBI:23117
chlorine molecular entity
Any haloalkane that consists of an alkane substituted by at least one chloro group.
chloroalkane
chebi_ontology
alkyl chloride
alkyl chlorides
chloroalkanes
CHEBI:23128
chloroalkane
chloroalkane
ChEBI
alkyl chloride
ChEBI
alkyl chlorides
ChEBI
chloroalkanes
ChEBI
chebi_ontology
CHEBI:23239
chromopeptide
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
Wikipedia:Cofactor_(biochemistry)
cofactor
cofactors
chebi_ontology
CHEBI:23357
cofactor
cofactor
IUPAC
cofactors
IUPAC
An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.
0
C22H25NO6
InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
IAKHMKGGTNLKSZ-UHFFFAOYSA-N
399.43704
399.16819
COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC
Beilstein:2228812
CAS:54192-66-4
DrugBank:DB01394
HMDB:HMDB0015466
LINCS:LSM-6449
PMID:10680067
PMID:24074178
PMID:7200520
PMID:9819133
Reaxys:2228812
N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
FlyBase miscellaneous CV
chebi_ontology
CHEBI:23359
colchicine
Beilstein:2228812
Beilstein
CAS:54192-66-4
NIST Chemistry WebBook
PMID:10680067
Europe PMC
PMID:24074178
Europe PMC
PMID:7200520
Europe PMC
PMID:9819133
Europe PMC
Reaxys:2228812
Reaxys
N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide
IUPAC
Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
molecular entity
chebi_ontology
entidad molecular
entidades moleculares
entite moleculaire
molecular entities
molekulare Entitaet
CHEBI:23367
molecular entity
molecular entity
IUPAC
entidad molecular
IUPAC
entidades moleculares
IUPAC
entite moleculaire
IUPAC
molecular entities
IUPAC
molekulare Entitaet
ChEBI
copper molecular entity
chebi_ontology
copper compounds
copper molecular entities
CHEBI:23377
copper molecular entity
copper molecular entity
ChEBI
copper compounds
ChEBI
copper molecular entities
ChEBI
Cu
63.546
62.92960
copper cation
chebi_ontology
Cu cation
copper cations
CHEBI:23378
copper cation
copper cation
IUPAC
Cu cation
UniProt
copper cations
ChEBI
A metal sulfate compound having copper(2+) as the metal ion.
0
CuO4S
InChI=1S/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
ARUVKPQLZAKDPS-UHFFFAOYSA-L
159.60960
158.88133
[Cu++].[O-]S([O-])(=O)=O
CAS:7758-98-7
Gmelin:8294
KEGG:C18713
PMID:10469300
PMID:29079364
PMID:8566016
PPDB:178
Wikipedia:Copper(II)_sulfate
Copper(II) sulfate
copper(2+) sulfate
copper(II) sulfate
FlyBase miscellaneous CV
chebi_ontology
CuSO4
Cupric sulfate
copper sulfate
cupric sulfate anhydrous
CHEBI:23414
copper(II) sulfate
CAS:7758-98-7
ChemIDplus
CAS:7758-98-7
KEGG COMPOUND
Gmelin:8294
Gmelin
PMID:10469300
Europe PMC
PMID:29079364
Europe PMC
PMID:8566016
Europe PMC
Copper(II) sulfate
KEGG_COMPOUND
copper(2+) sulfate
IUPAC
copper(II) sulfate
IUPAC
CuSO4
IUPAC
Cupric sulfate
ChemIDplus
copper sulfate
ChemIDplus
cupric sulfate anhydrous
ChemIDplus
An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues.
cysteine derivative
chebi_ontology
CHEBI:23509
cysteine derivative
cysteine derivative
ChEBI
0
C4H6O2
InChI=1S/C4H6O2/c1-3(5-1)4-2-6-4/h3-4H,1-2H2
ZFIVKAOQEXOYFY-UHFFFAOYSA-N
86.08924
86.03678
C1OC1C1CO1
Beilstein:79831
CAS:1464-53-5
2,2'-bioxirane
FlyBase miscellaneous CV
chebi_ontology
1,1'-bi[ethylene oxide]
1,2:3,4-butadiene diepoxide
1,2:3,4-dianhydrothreitol
1,2:3,4-diepoxybutane
1,3-butadiene diepoxide
Butadiendioxyd
DEB
bioxirane
butadiene diepoxide
butadiene dioxide
butane diepoxide
dioxybutadiene
CHEBI:23704
diepoxybutane
Beilstein:79831
Beilstein
CAS:1464-53-5
ChemIDplus
CAS:1464-53-5
NIST Chemistry WebBook
2,2'-bioxirane
IUPAC
1,1'-bi[ethylene oxide]
NIST_Chemistry_WebBook
1,2:3,4-butadiene diepoxide
ChemIDplus
1,2:3,4-dianhydrothreitol
NIST_Chemistry_WebBook
1,2:3,4-diepoxybutane
ChemIDplus
1,3-butadiene diepoxide
NIST_Chemistry_WebBook
Butadiendioxyd
ChemIDplus
DEB
NIST_Chemistry_WebBook
bioxirane
NIST_Chemistry_WebBook
butadiene diepoxide
NIST_Chemistry_WebBook
butadiene dioxide
NIST_Chemistry_WebBook
butane diepoxide
NIST_Chemistry_WebBook
dioxybutadiene
ChemIDplus
0
C8H14O2
InChI=1S/C8H14O2/c1(3-7-5-9-7)2-4-8-6-10-8/h7-8H,1-6H2
LFKLPJRVSHJZPL-UHFFFAOYSA-N
142.19556
142.09938
C(CCC1CO1)CC1CO1
Beilstein:104873
CAS:2426-07-5
2,2'-butane-1,4-diyldioxirane
FlyBase miscellaneous CV
chebi_ontology
1,2,7,8-Diepoxyoctane
1,2-Epoxy-7,8-epoxyoctane
1,7-Octadiene diepoxide
2,2'-(1,4-Butanediyl)bisoxirane
CHEBI:23705
1,2:7,8-diepoxyoctane
Beilstein:104873
Beilstein
CAS:2426-07-5
ChemIDplus
CAS:2426-07-5
NIST Chemistry WebBook
2,2'-butane-1,4-diyldioxirane
IUPAC
1,2,7,8-Diepoxyoctane
ChemIDplus
1,2-Epoxy-7,8-epoxyoctane
ChemIDplus
1,7-Octadiene diepoxide
ChemIDplus
2,2'-(1,4-Butanediyl)bisoxirane
ChemIDplus
A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols.
Wikipedia:Diol
diols
chebi_ontology
CHEBI:23824
diol
diols
IUPAC
Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
chebi_ontology
drugs
medicine
CHEBI:23888
drug
drugs
ChEBI
medicine
ChEBI
chebi_ontology
monoatomic anions
CHEBI:23905
monoatomic anion
monoatomic anions
ChEBI
chebi_ontology
monoatomic cations
CHEBI:23906
monoatomic cation
monoatomic cations
ChEBI
A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
enzyme inhibitor
chebi_ontology
enzyme inhibitors
inhibidor enzimatico
inhibidores enzimaticos
inhibiteur enzymatique
inhibiteurs enzymatiques
CHEBI:23924
enzyme inhibitor
enzyme inhibitor
IUPAC
enzyme inhibitors
ChEBI
inhibidor enzimatico
ChEBI
inhibidores enzimaticos
ChEBI
inhibiteur enzymatique
ChEBI
inhibiteurs enzymatiques
ChEBI
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
0
C3H8O3S
InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
PLUBXMRUUVWRLT-UHFFFAOYSA-N
124.15900
124.01942
CCOS(C)(=O)=O
CAS:62-50-0
KEGG:C19239
PMID:16039156
PMID:19797863
PMID:20102787
PMID:24475756
PMID:24524729
PMID:24531730
PMID:24728647
PMID:6936603
PMID:7285888
Reaxys:773969
Wikipedia:Ethyl_methanesulfonate
FlyBase miscellaneous CV
chebi_ontology
EMS
ethyl mesylate
ethyl methanesulphonate
methylsulfonic acid ethyl ester
methylsulfonic acid, ethyl ester
CHEBI:23994
ethyl methanesulfonate
CAS:62-50-0
ChemIDplus
CAS:62-50-0
KEGG COMPOUND
CAS:62-50-0
NIST Chemistry WebBook
PMID:16039156
Europe PMC
PMID:19797863
Europe PMC
PMID:20102787
Europe PMC
PMID:24475756
Europe PMC
PMID:24524729
Europe PMC
PMID:24531730
Europe PMC
PMID:24728647
Europe PMC
PMID:6936603
Europe PMC
PMID:7285888
Europe PMC
Reaxys:773969
Reaxys
EMS
ChemIDplus
ethyl mesylate
ChemIDplus
ethyl methanesulphonate
ChemIDplus
methylsulfonic acid ethyl ester
ChemIDplus
methylsulfonic acid, ethyl ester
ChemIDplus
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
0
C3H7N3O2
InChI=1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)
FUSGACRLAFQQRL-UHFFFAOYSA-N
117.10660
117.05383
CCN(N=O)C(N)=O
Beilstein:1761174
CAS:759-73-9
KEGG:C19178
PMID:11732210
PMID:11853764
PMID:11880538
PMID:16423555
PMID:21861612
PMID:22012195
PMID:22238669
PMID:23551873
PMID:24175309
PMID:8603364
Reaxys:1761174
Wikipedia:ENU
1-ethyl-1-nitrosourea
FlyBase miscellaneous CV
chebi_ontology
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine
1-Ethyl-1-nitrosourea
Aethylnitroso-harnstoff
ENU
Ethyl nitrosourea
N-Ethyl-N-nitroso carbamide
N-Ethyl-N-nitroso-urea
N-Ethylnitrosourea
NEU
CHEBI:23995
N-ethyl-N-nitrosourea
Beilstein:1761174
Beilstein
CAS:759-73-9
ChemIDplus
CAS:759-73-9
KEGG COMPOUND
CAS:759-73-9
NIST Chemistry WebBook
PMID:11732210
Europe PMC
PMID:11853764
Europe PMC
PMID:11880538
Europe PMC
PMID:16423555
Europe PMC
PMID:21861612
Europe PMC
PMID:22012195
Europe PMC
PMID:22238669
Europe PMC
PMID:23551873
Europe PMC
PMID:24175309
Europe PMC
PMID:8603364
Europe PMC
Reaxys:1761174
Reaxys
1-ethyl-1-nitrosourea
IUPAC
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine
NIST_Chemistry_WebBook
1-Ethyl-1-nitrosourea
ChemIDplus
Aethylnitroso-harnstoff
ChemIDplus
ENU
ChemIDplus
Ethyl nitrosourea
ChemIDplus
N-Ethyl-N-nitroso carbamide
ChemIDplus
N-Ethyl-N-nitroso-urea
ChemIDplus
N-Ethylnitrosourea
ChemIDplus
NEU
NIST_Chemistry_WebBook
An aliphatic sulfide in which the sulfur atom is bonded to at least one ethyl group.
chebi_ontology
ethyl sulfides
CHEBI:23996
ethyl sulfide
ethyl sulfides
ChEBI
chebi_ontology
fluoride salts
fluorides
CHEBI:24060
fluoride salt
fluoride salts
ChEBI
fluorides
ChEBI
0
F
InChI=1S/F
YCKRFDGAMUMZLT-UHFFFAOYSA-N
18.99840
18.99840
[F]
CAS:7782-41-4
WebElements:F
fluorine
chebi_ontology
9F
F
Fluor
fluor
fluorine
fluorum
CHEBI:24061
fluorine atom
CAS:7782-41-4
ChemIDplus
fluorine
IUPAC
9F
IUPAC
F
IUPAC
Fluor
ChemIDplus
fluor
ChEBI
fluorine
ChEBI
fluorum
ChEBI
fluorine molecular entity
chebi_ontology
fluorine compounds
fluorine molecular entities
CHEBI:24062
fluorine molecular entity
fluorine molecular entity
ChEBI
fluorine compounds
ChEBI
fluorine molecular entities
ChEBI
An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues.
chebi_ontology
CHEBI:24315
glutamic acid derivative
An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class.
PMID:20716061
chebi_ontology
glutamine family amino acids
CHEBI:24318
glutamine family amino acid
PMID:20716061
Europe PMC
glutamine family amino acids
ChEBI
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).
Wikipedia:Glutamine_synthetase
chebi_ontology
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
EC 6.3.1.2 inhibitor
EC 6.3.1.2 inhibitors
L-glutamate:ammonia ligase (ADP-forming) inhibitor
L-glutamate:ammonia ligase (ADP-forming) inhibitors
L-glutamine synthetase inhibitor
L-glutamine synthetase inhibitors
glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
glutamate--ammonia ligase inhibitor
glutamate--ammonia ligase inhibitors
glutamine synthetase inhibitor
glutamine synthetase inhibitors
glutamylhydroxamic synthetase inhibitor
glutamylhydroxamic synthetase inhibitors
CHEBI:24319
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
ChEBI
EC 6.3.1.2 inhibitor
ChEBI
EC 6.3.1.2 inhibitors
ChEBI
L-glutamate:ammonia ligase (ADP-forming) inhibitor
ChEBI
L-glutamate:ammonia ligase (ADP-forming) inhibitors
ChEBI
L-glutamine synthetase inhibitor
ChEBI
L-glutamine synthetase inhibitors
ChEBI
glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
ChEBI
glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
ChEBI
glutamate--ammonia ligase inhibitor
ChEBI
glutamate--ammonia ligase inhibitors
ChEBI
glutamine synthetase inhibitor
ChEBI
glutamine synthetase inhibitors
ChEBI
glutamylhydroxamic synthetase inhibitor
ChEBI
glutamylhydroxamic synthetase inhibitors
ChEBI
A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
glycosides
chebi_ontology
O-glycoside
O-glycosides
glycosides
CHEBI:24400
glycoside
glycosides
IUPAC
O-glycoside
ChEBI
O-glycosides
ChEBI
glycosides
ChEBI
A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
chemical entity
FlyBase miscellaneous CV
chebi_ontology
CHEBI:24431
chemical entity
chemical entity
UniProt
A role played by the molecular entity or part thereof within a biological context.
chebi_ontology
biological function
CHEBI:24432
biological role
biological function
ChEBI
A defined linked collection of atoms or a single atom within a molecular entity.
group
chebi_ontology
Gruppe
Rest
groupe
grupo
grupos
CHEBI:24433
group
group
IUPAC
Gruppe
ChEBI
Rest
ChEBI
groupe
IUPAC
grupo
IUPAC
grupos
IUPAC
Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas.
chebi_ontology
CHEBI:24436
guanidines
An organohalogen compound that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom.
chebi_ontology
alkyl halide
alkyl halides
haloalkanes
CHEBI:24469
haloalkane
alkyl halide
ChEBI
alkyl halides
ChEBI
haloalkanes
ChEBI
halogen molecular entity
chebi_ontology
halogen compounds
halogen molecular entities
CHEBI:24471
halogen molecular entity
halogen molecular entity
ChEBI
halogen compounds
ChEBI
halogen molecular entities
ChEBI
A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom.
chebi_ontology
halogenated hydrocarbons
halohydrocarbons
CHEBI:24472
halohydrocarbon
halogenated hydrocarbons
ChEBI
halohydrocarbons
ChEBI
halogen
halogens
chebi_ontology
Halogene
group 17 elements
group VII elements
halogene
halogenes
halogeno
halogenos
CHEBI:24473
halogen
halogen
IUPAC
halogens
IUPAC
Halogene
ChEBI
group 17 elements
ChEBI
group VII elements
ChEBI
halogene
ChEBI
halogenes
ChEBI
halogeno
ChEBI
halogenos
ChEBI
A cyclic compound having as ring members atoms of carbon and at least of one other element.
chebi_ontology
organic heterocycle
organic heterocyclic compounds
CHEBI:24532
organic heterocyclic compound
organic heterocycle
ChEBI
organic heterocyclic compounds
ChEBI
0
C9H18N6
InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
UUVWYPNAQBNQJQ-UHFFFAOYSA-N
210.27966
210.15929
CN(C)c1nc(nc(n1)N(C)C)N(C)C
Beilstein:195058
CAS:645-05-6
Drug_Central:141
Gmelin:603940
LINCS:LSM-3492
Patent:DE1240870
Patent:US3424752
Wikipedia:Altretamine
N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
FlyBase miscellaneous CV
chebi_ontology
2,4,6-tris(dimethylamino)-1,3,5-triazine
2,4,6-tris(dimethylamino)-s-triazine
HMM
Hexalen
Hexastat
altretamina
altretamine
altretaminum
CHEBI:24564
hexamethylmelamine
Beilstein:195058
Beilstein
CAS:645-05-6
ChemIDplus
CAS:645-05-6
NIST Chemistry WebBook
Drug_Central:141
DrugCentral
Gmelin:603940
Gmelin
N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
IUPAC
2,4,6-tris(dimethylamino)-1,3,5-triazine
ChemIDplus
2,4,6-tris(dimethylamino)-s-triazine
NIST_Chemistry_WebBook
HMM
ChemIDplus
Hexalen
ChemIDplus
Hexastat
ChemIDplus
altretamina
ChemIDplus
altretamine
ChemIDplus
altretaminum
ChemIDplus
0
C6H18N3OP
InChI=1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3
GNOIPBMMFNIUFM-UHFFFAOYSA-N
179.20050
179.11875
CN(C)P(=O)(N(C)C)N(C)C
Beilstein:1099903
CAS:680-31-9
Gmelin:3259
KEGG:C19250
N,N,N',N',N'',N''-hexamethylphosphoric triamide
hexamethylphosphoric triamide
FlyBase miscellaneous CV
chebi_ontology
HEMPA
HMPA
HMPT
HMPTA
Hexamethylphosphoramid
Hexamethylphosphorsaeuretriamid
hexamethylorthophosphoric triamide
hexamethylphosphoramide
hexamethylphosphoric acid triamide
phosphoric acid hexamethyltriamide
phosphoric hexamethyltriamide
phosphoric tris(dimethylamide)
CHEBI:24565
hexamethylphosphoric triamide
Beilstein:1099903
Beilstein
CAS:680-31-9
ChemIDplus
CAS:680-31-9
KEGG COMPOUND
CAS:680-31-9
NIST Chemistry WebBook
Gmelin:3259
Gmelin
N,N,N',N',N'',N''-hexamethylphosphoric triamide
IUPAC
hexamethylphosphoric triamide
ChemIDplus
HEMPA
NIST_Chemistry_WebBook
HMPA
ChemIDplus
HMPA
KEGG_COMPOUND
HMPT
ChemIDplus
HMPTA
ChemIDplus
Hexamethylphosphoramid
ChEBI
Hexamethylphosphorsaeuretriamid
ChEBI
hexamethylorthophosphoric triamide
NIST_Chemistry_WebBook
hexamethylphosphoramide
ChEBI
hexamethylphosphoric acid triamide
ChemIDplus
phosphoric acid hexamethyltriamide
NIST_Chemistry_WebBook
phosphoric hexamethyltriamide
NIST_Chemistry_WebBook
phosphoric tris(dimethylamide)
NIST_Chemistry_WebBook
A methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
0
C21H28N2O5S2
InChI=1S/C20H24N2O2S.CH4O3S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20;1-5(2,3)4/h5-10,21,23H,3-4,11-13H2,1-2H3;1H3,(H,2,3,4)
LOEQGPPJCCUXEJ-UHFFFAOYSA-N
452.58700
452.14396
CS(O)(=O)=O.CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12
CAS:23255-93-8
KEGG:C19432
PMID:1206768
PMID:1618027
PMID:2266978
PMID:2499511
PMID:2503417
PMID:3104567
PMID:6408464
PMID:6815525
PMID:8375330
Reaxys:4096157
1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-10H-dibenzo[b,e]thiopyran-10-one methanesulfonate
FlyBase miscellaneous CV
chebi_ontology
Etrenol
N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium methanesulfonate
N-[2-(diethylamino)ethyl]-4-methoxy-9-oxoxanthene-1-amine monomethanesulfonate
hycanthone methanesulfonate
hycanthone methanesulphonate
hycanthone monomesylate
hycanthone monomethanesulfonate
hycanthone monomethanesulphonate
CHEBI:24624
hycanthone mesylate
CAS:23255-93-8
ChemIDplus
CAS:23255-93-8
KEGG COMPOUND
PMID:1206768
Europe PMC
PMID:1618027
Europe PMC
PMID:2266978
Europe PMC
PMID:2499511
Europe PMC
PMID:2503417
Europe PMC
PMID:3104567
Europe PMC
PMID:6408464
Europe PMC
PMID:6815525
Europe PMC
PMID:8375330
Europe PMC
Reaxys:4096157
Reaxys
1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-10H-dibenzo[b,e]thiopyran-10-one methanesulfonate
IUPAC
Etrenol
ChEBI
N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium methanesulfonate
IUPAC
N-[2-(diethylamino)ethyl]-4-methoxy-9-oxoxanthene-1-amine monomethanesulfonate
ChEBI
hycanthone methanesulfonate
ChemIDplus
hycanthone methanesulphonate
ChemIDplus
hycanthone monomesylate
ChEBI
hycanthone monomethanesulfonate
ChemIDplus
hycanthone monomethanesulphonate
ChemIDplus
A compound consisting of carbon and hydrogen only.
hydrocarbon
hydrocarbons
chebi_ontology
Kohlenwasserstoff
Kohlenwasserstoffe
hidrocarburo
hidrocarburos
hydrocarbure
CHEBI:24632
hydrocarbon
hydrocarbon
IUPAC
hydrocarbons
IUPAC
Kohlenwasserstoff
ChEBI
Kohlenwasserstoffe
ChEBI
hidrocarburo
IUPAC
hidrocarburos
IUPAC
hydrocarbure
IUPAC
Benzenediols that have the hydroxy substituents in the 1- and 4-positions.
0
C6H2O2R4
106.079
106.00548
OC1=C(*)C(*)=C(O)C(*)=C1*
CHEBI:134188
chebi_ontology
1,4-benzoquinols
a 1,4-benzoquinol
a quinol
benzene-1,4-diols
CHEBI:24646
hydroquinones
1,4-benzoquinols
ChEBI
a 1,4-benzoquinol
ChEBI
a quinol
UniProt
benzene-1,4-diols
ChEBI
Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
chebi_ontology
CHEBI:24651
hydroxides
A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents.
hydroxyflavanone
chebi_ontology
hydroxyflavanones
CHEBI:24697
hydroxyflavanone
hydroxyflavanone
ChEBI
hydroxyflavanones
ChEBI
Any member of the class of naphthalenes that is naphthalene carrying one or more hydroxy groups.
chebi_ontology
CHEBI:24727
hydroxynaphthalene
A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
oxoacid
oxoacids
chebi_ontology
oxacids
oxiacids
oxo acid
oxy-acids
oxyacids
CHEBI:24833
oxoacid
oxoacid
IUPAC
oxoacids
IUPAC
oxacids
ChEBI
oxiacids
ChEBI
oxo acid
ChEBI
oxy-acids
ChEBI
oxyacids
ChEBI
chebi_ontology
inorganic anions
CHEBI:24834
inorganic anion
inorganic anions
ChEBI
A molecular entity that contains no carbon.
FlyBase miscellaneous CV
chebi_ontology
anorganische Verbindungen
inorganic compounds
inorganic entity
inorganic molecular entities
inorganics
CHEBI:24835
inorganic molecular entity
anorganische Verbindungen
ChEBI
inorganic compounds
ChEBI
inorganic entity
ChEBI
inorganic molecular entities
ChEBI
inorganics
ChEBI
chebi_ontology
inorganic oxides
CHEBI:24836
inorganic oxide
inorganic oxides
ChEBI
chebi_ontology
anorganisches Salz
inorganic salts
CHEBI:24839
inorganic salt
anorganisches Salz
ChEBI
inorganic salts
ChEBI
chebi_ontology
inorganic sulfate salts
inorganic sulfates
CHEBI:24840
inorganic sulfate salt
inorganic sulfate salts
ChEBI
inorganic sulfates
ChEBI
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
Wikipedia:Insecticide
chebi_ontology
insecticides
CHEBI:24852
insecticide
insecticides
ChEBI
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
chebi_ontology
agente intercalante
intercalating agent
intercalating agents
intercalating ligands
intercalators
CHEBI:24853
intercalator
agente intercalante
ChEBI
intercalating agent
ChEBI
intercalating agents
ChEBI
intercalating ligands
ChEBI
intercalators
ChEBI
Chemical element with atomic number 53.
0
I
InChI=1S/I
ZCYVEMRRCGMTRW-UHFFFAOYSA-N
126.90447
126.90447
[I]
WebElements:I
iodine
FlyBase miscellaneous CV
chebi_ontology
53I
I
Iod
J
Jod
iode
iodine
iodium
yodo
CHEBI:24859
iodine atom
iodine
IUPAC
53I
IUPAC
I
ChEBI
Iod
ChEBI
J
ChEBI
Jod
ChEBI
iode
ChEBI
iodine
ChEBI
iodium
ChEBI
yodo
ChEBI
A salt is an assembly of cations and anions.
salt
chebi_ontology
Salz
Salze
ionic compound
ionic compounds
sal
sales
salts
sel
sels
CHEBI:24866
salt
salt
IUPAC
Salz
ChEBI
Salze
ChEBI
ionic compound
ChEBI
ionic compounds
ChEBI
sal
ChEBI
sales
ChEBI
salts
ChEBI
sel
ChEBI
sels
ChEBI
chebi_ontology
monoatomic ions
CHEBI:24867
monoatomic ion
monoatomic ions
ChEBI
chebi_ontology
organic salts
organisches Salz
CHEBI:24868
organic salt
organic salts
ChEBI
organisches Salz
ChEBI
A molecular entity having a net electric charge.
Ion
ion
chebi_ontology
Ionen
iones
ions
CHEBI:24870
ion
Ion
ChEBI
ion
ChEBI
ion
IUPAC
Ionen
ChEBI
iones
ChEBI
ions
ChEBI
Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine.
chebi_ontology
isoquinoline alkaloids
CHEBI:24921
isoquinoline alkaloid
isoquinoline alkaloids
ChEBI
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
CHEBI:26619
CHEBI:35220
metabolite
chebi_ontology
metabolites
primary metabolites
secondary metabolites
CHEBI:25212
metabolite
metabolite
IUPAC
metabolites
ChEBI
primary metabolites
ChEBI
secondary metabolites
ChEBI
chebi_ontology
a metal cation
metal cations
CHEBI:25213
metal cation
a metal cation
UniProt
metal cations
ChEBI
An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol.
0
CH3O3SR
95.099
94.98029
CS(O*)(=O)=O
chebi_ontology
mesylate ester
mesylate esters
methanesulfonic acid esters
CHEBI:25223
methanesulfonate ester
mesylate ester
ChEBI
mesylate esters
ChEBI
methanesulfonic acid esters
ChEBI
A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid.
-1
CH3O3S
InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1
AFVFQIVMOAPDHO-UHFFFAOYSA-M
95.09872
94.98084
CS([O-])(=O)=O
MetaCyc:CPD-3746
UM-BBD_compID:c0347
methanesulfonate
chebi_ontology
methylsulfonate
CHEBI:25224
methanesulfonate
UM-BBD_compID:c0347
UM-BBD
methanesulfonate
IUPAC
methanesulfonate
UniProt
methylsulfonate
UM-BBD
0
C5H12N2O2
InChI=1S/C5H12N2O2/c1-4-7(6-8)5(2)9-3/h5H,4H2,1-3H3
DCUKVUVLSDGDEZ-UHFFFAOYSA-N
132.16106
132.08988
CCN(N=O)C(C)OC
Beilstein:4368978
CAS:61738-03-2
N-ethyl-1-methoxy-N-nitrosoethanamine
FlyBase miscellaneous CV
chebi_ontology
CHEBI:25234
1-methoxy-N-nitrosodiethylamine
Beilstein:4368978
ChemIDplus
CAS:61738-03-2
ChemIDplus
N-ethyl-1-methoxy-N-nitrosoethanamine
IUPAC
A member of the class of flavanones that consists of flavanone with one or more methoxy substituents.
chebi_ontology
methoxyflavanones
CHEBI:25240
methoxyflavanone
methoxyflavanones
ChEBI
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol.
0
C2H6O3S
InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3
MBABOKRGFJTBAE-UHFFFAOYSA-N
110.13200
110.00377
COS(C)(=O)=O
CAS:66-27-3
KEGG:C19181
MetaCyc:CPD-7038
PMID:11016630
PMID:14761437
PMID:16764919
PMID:21353429
PMID:21860482
PMID:22907509
PMID:23117069
PMID:23384783
PMID:23483329
Reaxys:1098586
Wikipedia:Methyl_methanesulfonate
methyl methanesulfonate
FlyBase miscellaneous CV
chebi_ontology
CB1540
MMS
Methanesulfonic acid methyl ester
Methyl mesylate
as-Dimethyl sulfite
CHEBI:25255
methyl methanesulfonate
CAS:66-27-3
ChemIDplus
CAS:66-27-3
KEGG COMPOUND
PMID:11016630
Europe PMC
PMID:14761437
Europe PMC
PMID:16764919
Europe PMC
PMID:21353429
Europe PMC
PMID:21860482
Europe PMC
PMID:22907509
Europe PMC
PMID:23117069
Europe PMC
PMID:23384783
Europe PMC
PMID:23483329
Europe PMC
Reaxys:1098586
Reaxys
methyl methanesulfonate
IUPAC
CB1540
ChEBI
MMS
ChemIDplus
MMS
KEGG_COMPOUND
Methanesulfonic acid methyl ester
ChemIDplus
Methyl mesylate
ChemIDplus
as-Dimethyl sulfite
ChemIDplus
chebi_ontology
methylxanthines
CHEBI:25348
methylxanthine
methylxanthines
ChEBI
A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
PMID:19777135
Wikipedia:Mitomycin
chebi_ontology
mitomycins
CHEBI:25357
mitomycin
PMID:19777135
Europe PMC
mitomycins
ChEBI
Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
molecule
chebi_ontology
Molekuel
molecula
molecules
neutral molecular compounds
CHEBI:25367
molecule
molecule
IUPAC
Molekuel
ChEBI
molecula
IUPAC
molecules
IUPAC
neutral molecular compounds
IUPAC
An oxoacid containing a single carboxy group.
chebi_ontology
monocarboxylic acids
CHEBI:25384
monocarboxylic acid
monocarboxylic acids
ChEBI
Any hydroxynaphthalene derivative that has a single hydroxy substituent.
chebi_ontology
CHEBI:25392
naphthols
+1
0.00000
[*+]
chebi_ontology
monoatomic monocations
monovalent inorganic cations
CHEBI:25414
monoatomic monocation
monoatomic monocations
ChEBI
monovalent inorganic cations
ChEBI
An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
0
C4H8Cl2S
InChI=1S/C4H8Cl2S/c5-1-3-7-4-2-6/h1-4H2
QKSKPIVNLNLAAV-UHFFFAOYSA-N
159.07772
157.97238
ClCCSCCCl
Beilstein:1733595
CAS:505-60-2
Gmelin:324535
KEGG:C19164
PMID:15908294
PMID:19559099
PMID:23091586
PMID:24467472
PMID:24641121
PMID:24791566
PMID:24801489
Wikipedia:Sulfur_mustard
1-chloro-2-[(2-chloroethyl)sulfanyl]ethane
bis(2-chloroethyl) sulfide
FlyBase miscellaneous CV
chebi_ontology
1,1'-thiobis(2-chloroethane)
1-chloro-2-[(2-chloroethyl)thio]ethane
Iprit
Lost
Mustard gas
Senfgas
Yperite
bis(2-chloroethyl) sulphide
bis(2-chloroethyl)sulfane
mustard gas
sulfur mustard
CHEBI:25434
bis(2-chloroethyl) sulfide
Beilstein:1733595
ChemIDplus
CAS:505-60-2
ChemIDplus
CAS:505-60-2
KEGG COMPOUND
CAS:505-60-2
NIST Chemistry WebBook
Gmelin:324535
Gmelin
PMID:15908294
Europe PMC
PMID:19559099
Europe PMC
PMID:23091586
Europe PMC
PMID:24467472
Europe PMC
PMID:24641121
Europe PMC
PMID:24791566
Europe PMC
PMID:24801489
Europe PMC
1-chloro-2-[(2-chloroethyl)sulfanyl]ethane
IUPAC
bis(2-chloroethyl) sulfide
ChemIDplus
1,1'-thiobis(2-chloroethane)
NIST_Chemistry_WebBook
1-chloro-2-[(2-chloroethyl)thio]ethane
IUPAC
Iprit
KEGG_COMPOUND
Lost
NIST_Chemistry_WebBook
Mustard gas
KEGG_COMPOUND
Senfgas
NIST_Chemistry_WebBook
Yperite
NIST_Chemistry_WebBook
bis(2-chloroethyl) sulphide
NIST_Chemistry_WebBook
bis(2-chloroethyl)sulfane
IUPAC
mustard gas
ChemIDplus
sulfur mustard
ChemIDplus
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
Wikipedia:Mutagen
chebi_ontology
mutagene
mutagenes
mutagenic agent
mutageno
mutagenos
mutagens
CHEBI:25435
mutagen
mutagene
ChEBI
mutagenes
ChEBI
mutagenic agent
ChEBI
mutageno
ChEBI
mutagenos
ChEBI
mutagens
ChEBI
Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings.
chebi_ontology
CHEBI:25477
naphthalenes
A substance used to destroy pests of the phylum Nematoda (roundworms).
Wikipedia:Nematicide
chebi_ontology
nematicides
nematocide
nematocides
CHEBI:25491
nematicide
nematicides
ChEBI
nematocide
ChEBI
nematocides
ChEBI
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
Wikipedia:Neurotransmitter
chebi_ontology
neurotransmitters
CHEBI:25512
neurotransmitter
neurotransmitters
ChEBI
0
N
14.007
14.00307
WebElements:N
nitrogen
chebi_ontology
7N
N
Stickstoff
azote
nitrogen
nitrogeno
CHEBI:25555
nitrogen atom
nitrogen
IUPAC
7N
IUPAC
N
IUPAC
Stickstoff
ChEBI
azote
IUPAC
nitrogen
ChEBI
nitrogeno
ChEBI
nonmetal
chebi_ontology
Nichtmetall
Nichtmetalle
no metal
no metales
non-metal
non-metaux
nonmetal
nonmetals
CHEBI:25585
nonmetal atom
nonmetal
IUPAC
Nichtmetall
ChEBI
Nichtmetalle
ChEBI
no metal
ChEBI
no metales
ChEBI
non-metal
ChEBI
non-metaux
ChEBI
nonmetal
ChEBI
nonmetals
ChEBI
chebi_ontology
organic heteromonocyclic compounds
CHEBI:25693
organic heteromonocyclic compound
organic heteromonocyclic compounds
ChEBI
Any organic ion with a net negative charge.
chebi_ontology
organic anions
CHEBI:25696
organic anion
organic anions
ChEBI
Any organic ion with a net positive charge.
chebi_ontology
organic cations
CHEBI:25697
organic cation
organic cations
ChEBI
An organooxygen compound with formula ROR, where R is not hydrogen.
0
OR2
15.99940
15.99491
[*]O[*]
ether
ethers
chebi_ontology
ethers
CHEBI:25698
ether
ether
IUPAC
ethers
IUPAC
ethers
ChEBI
chebi_ontology
organic ions
CHEBI:25699
organic ion
organic ions
ChEBI
Compounds of the general formula SO3HOR where R is an organyl group
chebi_ontology
organic sulfates
CHEBI:25704
organic sulfate
organic sulfates
ChEBI
An oxide is a chemical compound of oxygen with other chemical elements.
oxide
chebi_ontology
oxides
CHEBI:25741
oxide
oxide
ChEBI
oxides
ChEBI
0
O
InChI=1S/O
QVGXLLKOCUKJST-UHFFFAOYSA-N
15.99940
15.99491
[O]
KEGG:C00007
WebElements:O
oxygen
chebi_ontology
8O
O
Sauerstoff
oxigeno
oxygen
oxygene
CHEBI:25805
oxygen atom
oxygen
IUPAC
8O
IUPAC
O
IUPAC
Sauerstoff
ChEBI
oxigeno
ChEBI
oxygen
ChEBI
oxygene
ChEBI
oxygen molecular entity
chebi_ontology
oxygen molecular entities
CHEBI:25806
oxygen molecular entity
oxygen molecular entity
ChEBI
oxygen molecular entities
ChEBI
chebi_ontology
oxopurines
CHEBI:25810
oxopurine
oxopurines
ChEBI
FlyBase miscellaneous CV
chebi_ontology
CHEBI:25813
p-N,N-bis(2-chloroethyl)aminophenylvaleric acid
FlyBase miscellaneous CV
chebi_ontology
CHEBI:25814
p-N,N-bis(2-chloroethyl)amino-D-phenylalanine
FlyBase miscellaneous CV
chebi_ontology
CHEBI:25816
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
0
C12H18Cl2N2
InChI=1S/C12H18Cl2N2/c13-6-9-16(10-7-14)12-3-1-11(2-4-12)5-8-15/h1-4H,5-10,15H2
PJKCNYLAFQAJDD-UHFFFAOYSA-N
261.19020
260.08470
NCCc1ccc(cc1)N(CCCl)CCCl
Beilstein:3292665
CAS:58880-18-5
4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline
FlyBase miscellaneous CV
chebi_ontology
4-(bis(2-chloroethyl)amino)benzeneethanamine
CB 3034
p-(bis(2-chloroethyl)amino)phenethylamine
p-N,N-di-(2-chloroethyl)aminophenylethylamine
CHEBI:25818
4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline
Beilstein:3292665
ChemIDplus
CAS:58880-18-5
ChemIDplus
4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline
IUPAC
4-(bis(2-chloroethyl)amino)benzeneethanamine
ChemIDplus
CB 3034
ChemIDplus
p-(bis(2-chloroethyl)amino)phenethylamine
ChemIDplus
p-N,N-di-(2-chloroethyl)aminophenylethylamine
ChemIDplus
FlyBase miscellaneous CV
chebi_ontology
CHEBI:25829
p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine
A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring.
chebi_ontology
p-quinone
para-quinones
CHEBI:25830
p-quinones
p-quinone
ChEBI
para-quinones
ChEBI
chebi_ontology
CHEBI:25903
peptide antibiotic
Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
Wikipedia:Pesticide
pesticide
chebi_ontology
Pestizid
Pestizide
pesticides
CHEBI:25944
pesticide
pesticide
IUPAC
Pestizid
ChEBI
Pestizide
ChEBI
pesticides
ChEBI
An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine by a heteroatom. The definition normally excludes peptides containing phenylalanine residues.
chebi_ontology
CHEBI:25985
phenylalanine derivative
Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin.
Wikipedia:Phenylpropanoid
chebi_ontology
phenylpropanoids
CHEBI:26004
phenylpropanoid
phenylpropanoids
ChEBI
A phosphorus oxoacid that consits of one oxo and three hydroxy groups joined covalently to a central phosphorus atom.
0
H3O4P
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
NBIIXXVUZAFLBC-UHFFFAOYSA-N
97.99520
97.97690
[H]OP(=O)(O[H])O[H]
Beilstein:1921286
CAS:7664-38-2
Drug_Central:4478
Gmelin:2000
HMDB:HMDB0002142
KEGG:C00009
KEGG:D05467
KNApSAcK:C00007408
PMID:11455380
PMID:15630224
PMID:17439666
PMID:17518491
PMID:22282755
PMID:22333268
PMID:22381614
PMID:22401268
Reaxys:1921286
Wikipedia:Phosphoric_Acid
Phosphoric acid
phosphoric acid
tetraoxophosphoric acid
trihydrogen tetraoxophosphate(3-)
trihydroxidooxidophosphorus
chebi_ontology
H3PO4
Orthophosphoric acid
Phosphate
Phosphorsaeure
Phosphorsaeureloesungen
[PO(OH)3]
acide phosphorique
acidum phosphoricum
orthophosphoric acid
CHEBI:26078
phosphoric acid
Beilstein:1921286
Beilstein
CAS:7664-38-2
ChemIDplus
CAS:7664-38-2
KEGG COMPOUND
CAS:7664-38-2
NIST Chemistry WebBook
Drug_Central:4478
DrugCentral
Gmelin:2000
Gmelin
PMID:11455380
Europe PMC
PMID:15630224
Europe PMC
PMID:17439666
Europe PMC
PMID:17518491
Europe PMC
PMID:22282755
Europe PMC
PMID:22333268
Europe PMC
PMID:22381614
Europe PMC
PMID:22401268
Europe PMC
Reaxys:1921286
Reaxys
Phosphoric acid
KEGG_COMPOUND
phosphoric acid
IUPAC
tetraoxophosphoric acid
IUPAC
trihydrogen tetraoxophosphate(3-)
IUPAC
trihydroxidooxidophosphorus
IUPAC
H3PO4
IUPAC
Orthophosphoric acid
KEGG_COMPOUND
Phosphate
KEGG_COMPOUND
Phosphorsaeure
ChEBI
Phosphorsaeureloesungen
ChEBI
[PO(OH)3]
IUPAC
acide phosphorique
ChEBI
acidum phosphoricum
ChEBI
orthophosphoric acid
NIST_Chemistry_WebBook
chebi_ontology
phosphorus molecular entities
CHEBI:26082
phosphorus molecular entity
phosphorus molecular entities
ChEBI
Any amino acid whose side chain is capable of forming one or more hydrogen bonds as proton donors or acceptors.
0
C2H4NO2R
74.059
74.02420
OC(C(*)N)=O
CHEBI:8283
MetaCyc:Polar-amino-acids
PMID:12016058
polar amino acid
chebi_ontology
polar amino acids
polar amino-acid
polar amino-acids
CHEBI:26167
polar amino acid
PMID:12016058
Europe PMC
polar amino acid
ChEBI
polar amino acids
ChEBI
polar amino-acid
ChEBI
polar amino-acids
ChEBI
A compound that contains two or more hydroxy groups.
chebi_ontology
polyols
CHEBI:26191
polyol
polyols
ChEBI
Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine.
amidine
amidines
chebi_ontology
Amidines
amidines
CHEBI:2634
amidine
amidine
IUPAC
amidines
IUPAC
Amidines
KEGG_COMPOUND
amidines
ChEBI
chebi_ontology
CHEBI:26373
pteridines
chebi_ontology
CHEBI:26375
pterins
chebi_ontology
purine alkaloids
CHEBI:26385
purine alkaloid
purine alkaloids
ChEBI
A nucleobase whose skeleton is derived from purine.
0
C5H3N4R2
119.104
119.03577
C1(NC(=NC=2NC=NC12)*)=*
KEGG:C15587
purine nucleobase
chebi_ontology
a purine nucleobase
purine bases
purine nucleobases
CHEBI:26386
purine nucleobase
purine nucleobase
ChEBI
a purine nucleobase
UniProt
purine bases
ChEBI
purine nucleobases
ChEBI
A class of imidazopyrimidines that consists of purine and its substituted derivatives.
0
C5N4R7
116.080
116.01230
CHEBI:13678
chebi_ontology
CHEBI:26401
purines
A nucleobase whose skeleton is derived from pyrimidine.
0
C4HN2R4
77.064
77.01397
N1C(=C(C(=NC1=*)*)*)*
pyrimidine nucleobase
chebi_ontology
a pyrimidine nucleobase
pyrimidine bases
pyrimidine nucleobases
CHEBI:26432
pyrimidine nucleobase
pyrimidine nucleobase
ChEBI
a pyrimidine nucleobase
UniProt
pyrimidine bases
ChEBI
pyrimidine nucleobases
ChEBI
KEGG:C03169
chebi_ontology
N-D-Ribosylpyrimidine
pyrimidine nucleosides
CHEBI:26440
pyrimidine nucleoside
N-D-Ribosylpyrimidine
KEGG_COMPOUND
pyrimidine nucleosides
ChEBI
0
C12H10O4
InChI=1S/C6H6O2.C6H4O2/c2*7-5-1-2-6(8)4-3-5/h1-4,7-8H;1-4H
BDJXVNRFAQSMAA-UHFFFAOYSA-N
218.20540
218.05791
Oc1ccc(O)cc1.O=C1C=CC(=O)C=C1
Beilstein:3919222
CAS:106-34-3
Gmelin:253527
cyclohexa-2,5-diene-1,4-dione--benzene-1,4-diol (1:1)
FlyBase miscellaneous CV
chebi_ontology
Chinhydron
green hydroquinone
p-benzoquinhydrone
p-benzoquinone--hydroquinone compound (1:1)
CHEBI:26491
quinhydrone
Beilstein:3919222
Beilstein
CAS:106-34-3
ChemIDplus
CAS:106-34-3
NIST Chemistry WebBook
Gmelin:253527
Gmelin
cyclohexa-2,5-diene-1,4-dione--benzene-1,4-diol (1:1)
IUPAC
Chinhydron
ChemIDplus
green hydroquinone
NIST_Chemistry_WebBook
p-benzoquinhydrone
ChemIDplus
p-benzoquinone--hydroquinone compound (1:1)
NIST_Chemistry_WebBook
A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring.
chebi_ontology
CHEBI:26513
quinolines
rhamnosylglucoside
chebi_ontology
rhamnosylglucosides
CHEBI:26548
rhamnosylglucoside
rhamnosylglucoside
ChEBI
rhamnosylglucosides
ChEBI
rutinoside
chebi_ontology
rutinosides
CHEBI:26587
rutinoside
rutinoside
ChEBI
rutinosides
ChEBI
Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure.
chebi_ontology
s-triazines
CHEBI:26588
1,3,5-triazines
s-triazines
ChEBI
Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess.
PMID:16492686
PMID:19763019
PMID:20237329
saturated fatty acid
chebi_ontology
SFA
SFAs
saturated fatty acids
CHEBI:26607
saturated fatty acid
PMID:16492686
Europe PMC
PMID:19763019
Europe PMC
PMID:20237329
Europe PMC
saturated fatty acid
ChEBI
SFA
ChEBI
SFAs
ChEBI
saturated fatty acids
ChEBI
An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid.
0
CH2OR
45.017
44.99765
OC([*])=O
PMID:16633129
PMID:16870803
PMID:18203540
PMID:20148677
chebi_ontology
SCFA
SCFAs
short-chain fatty acids
CHEBI:26666
short-chain fatty acid
PMID:16633129
Europe PMC
PMID:16870803
Europe PMC
PMID:18203540
Europe PMC
PMID:20148677
Europe PMC
SCFA
ChEBI
SCFAs
ChEBI
short-chain fatty acids
ChEBI
0
Na
InChI=1S/Na
KEAYESYHFKHZAL-UHFFFAOYSA-N
22.98977
22.98977
[Na]
CAS:7440-23-5
Gmelin:16221
KEGG:C01330
WebElements:Na
sodium
chebi_ontology
11Na
Na
Natrium
natrium
sodio
sodium
CHEBI:26708
sodium atom
CAS:7440-23-5
ChemIDplus
Gmelin:16221
Gmelin
sodium
IUPAC
11Na
IUPAC
Na
IUPAC
Natrium
ChemIDplus
natrium
IUPAC
sodio
ChemIDplus
sodium
ChEBI
0
HNaO3S
InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1
DWAQJAXMDSEUJJ-UHFFFAOYSA-M
104.06191
103.95441
[Na+].OS([O-])=O
CAS:7631-90-5
Gmelin:22395
sodium hydrogensulfite
FlyBase miscellaneous CV
chebi_ontology
NaHSO3
Natriumbisulfit
Natriumhydrogensulfit
primaeres Natriumsulfit
saures Natriumsulfit
sodium bisulfite
sodium bisulphite
sodium hydrogen sulfite
CHEBI:26709
sodium hydrogensulfite
CAS:7631-90-5
ChemIDplus
Gmelin:22395
Gmelin
sodium hydrogensulfite
IUPAC
NaHSO3
IUPAC
Natriumbisulfit
ChEBI
Natriumhydrogensulfit
ChEBI
primaeres Natriumsulfit
ChEBI
saures Natriumsulfit
ChEBI
sodium bisulfite
ChemIDplus
sodium bisulphite
ChemIDplus
sodium hydrogen sulfite
ChemIDplus
chebi_ontology
sodium compounds
sodium molecular entities
CHEBI:26712
sodium molecular entity
sodium compounds
ChEBI
sodium molecular entities
ChEBI
Any alkali metal salt having sodium(1+) as the cation.
chebi_ontology
Natriumsalz
Natriumsalze
sodium salts
CHEBI:26714
sodium salt
Natriumsalz
ChEBI
Natriumsalze
ChEBI
sodium salts
ChEBI
FlyBase miscellaneous CV
chebi_ontology
CHEBI:26800
styrylquinoline
An ester of an alcohol and sulfuric acid.
0
O4SR2
96.06300
95.95173
[*]OS(=O)(=O)O[*]
chebi_ontology
sulfate ester
sulfuric acid ester
sulfuric acid esters
CHEBI:26819
sulfuric ester
sulfate ester
ChEBI
sulfuric acid ester
ChEBI
sulfuric acid esters
ChEBI
Salts and esters of sulfuric acid
sulfates
chebi_ontology
sulfuric acid derivative
sulphates
CHEBI:26820
sulfates
sulfates
ChEBI
sulfuric acid derivative
ChEBI
sulphates
ChEBI
Any sulfur molecular entity that involves either covalently bonded or anionic sulfur.
chebi_ontology
sulphides
CHEBI:26822
sulfide
sulphides
ChEBI
Any sulfurous acid derivative that is a salt or an ester of sulfurous acid.
Wikipedia:Sulfite
chebi_ontology
Sulfite
sulfito
sulfitos
sulphites
CHEBI:26823
sulfites
Sulfite
ChEBI
sulfito
ChEBI
sulfitos
ChEBI
sulphites
ChEBI
0
S
InChI=1S/S
NINIDFKCEFEMDL-UHFFFAOYSA-N
32.06600
31.97207
[S]
CAS:7704-34-9
KEGG:C00087
KEGG:D06527
PPDB:605
WebElements:S
sulfur
chebi_ontology
16S
Elemental sulfur
S
Schwefel
azufre
soufre
sulfur
sulphur
theion
CHEBI:26833
sulfur atom
CAS:7704-34-9
ChemIDplus
CAS:7704-34-9
NIST Chemistry WebBook
sulfur
IUPAC
16S
IUPAC
Elemental sulfur
KEGG_COMPOUND
S
IUPAC
S
KEGG_COMPOUND
Schwefel
ChEBI
azufre
ChEBI
soufre
ChEBI
sulfur
ChEBI
sulfur
UniProt
sulphur
ChEBI
theion
IUPAC
chebi_ontology
sulfur-containing amino acids
CHEBI:26834
sulfur-containing amino acid
sulfur-containing amino acids
ChEBI
sulfur molecular entity
chebi_ontology
sulfur molecular entities
CHEBI:26835
sulfur molecular entity
sulfur molecular entity
ChEBI
sulfur molecular entities
ChEBI
A sulfur oxoacid that consits of two oxo and two hydroxy groups joined covalently to a central sulfur atom.
0
H2O4S
InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)
QAOWNCQODCNURD-UHFFFAOYSA-N
98.07948
97.96738
[H]OS(=O)(=O)O[H]
CAS:7664-93-9
Gmelin:2122
KEGG:C00059
KEGG:D05963
KNApSAcK:C00007530
MolBase:4
PMID:13568755
PMID:16122922
PMID:19397353
PMID:22047659
PMID:22136045
PMID:22204399
PMID:22267186
PMID:22296037
PMID:22364556
PMID:22435616
PPDB:606
Reaxys:2037554
Wikipedia:Sulfuric_acid
Sulfuric acid
dihydrogen tetraoxosulfate
dihydroxidodioxidosulfur
hydrogen tetraoxosulfate(2-)
hydrogen tetraoxosulfate(VI)
sulfuric acid
tetraoxosulfuric acid
chebi_ontology
Acide sulfurique
Acido sulfurico
Acidum sulfuricum
H2SO4
Schwefelsaeureloesungen
[S(OH)2O2]
[SO2(OH)2]
sulphuric acid
CHEBI:26836
sulfuric acid
CAS:7664-93-9
ChemIDplus
CAS:7664-93-9
KEGG COMPOUND
CAS:7664-93-9
NIST Chemistry WebBook
Gmelin:2122
Gmelin
PMID:13568755
Europe PMC
PMID:16122922
Europe PMC
PMID:19397353
Europe PMC
PMID:22047659
Europe PMC
PMID:22136045
Europe PMC
PMID:22204399
Europe PMC
PMID:22267186
Europe PMC
PMID:22296037
Europe PMC
PMID:22364556
Europe PMC
PMID:22435616
Europe PMC
Reaxys:2037554
Reaxys
Sulfuric acid
KEGG_COMPOUND
dihydrogen tetraoxosulfate
IUPAC
dihydroxidodioxidosulfur
IUPAC
hydrogen tetraoxosulfate(2-)
IUPAC
hydrogen tetraoxosulfate(VI)
IUPAC
sulfuric acid
ChEBI
sulfuric acid
IUPAC
tetraoxosulfuric acid
IUPAC
Acide sulfurique
ChemIDplus
Acido sulfurico
ChemIDplus
Acidum sulfuricum
ChemIDplus
H2SO4
IUPAC
Schwefelsaeureloesungen
ChemIDplus
[S(OH)2O2]
MolBase
[SO2(OH)2]
IUPAC
sulphuric acid
MolBase
Any oxacycle having an oxolane (tetrahydrofuran) skeleton.
chebi_ontology
CHEBI:26912
oxolanes
An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms.
chebi_ontology
heterotricyclic compounds
organic heterotricyclic compounds
CHEBI:26979
organic heterotricyclic compound
heterotricyclic compounds
ChEBI
organic heterotricyclic compounds
ChEBI
Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group.
chebi_ontology
CHEBI:27024
toluenes
Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Wikipedia:Micronutrient
chebi_ontology
micronutrients
trace elements
CHEBI:27027
micronutrient
micronutrients
ChEBI
trace elements
ChEBI
An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.
transition element
chebi_ontology
Uebergangselement
Uebergangsmetalle
metal de transicion
metal de transition
metales de transicion
metaux de transition
transition element
transition elements
transition metal
transition metals
CHEBI:27081
transition element atom
transition element
IUPAC
Uebergangselement
ChEBI
Uebergangsmetalle
ChEBI
metal de transicion
ChEBI
metal de transition
ChEBI
metales de transicion
ChEBI
metaux de transition
ChEBI
transition element
ChEBI
transition elements
ChEBI
transition metal
ChEBI
transition metals
ChEBI
A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups.
0
C12H13N3O2
InChI=1S/C12H13N3O2/c16-9-7-8(13-1-2-13)12(17)11(15-5-6-15)10(9)14-3-4-14/h7H,1-6H2
PXSOHRWMIRDKMP-UHFFFAOYSA-N
231.25050
231.10078
O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1
CAS:68-76-8
Drug_Central:4372
KEGG:C19542
KEGG:D07254
PMID:146335
PMID:20371239
PMID:362189
PMID:3672382
PMID:582920
PMID:624547
PMID:74416
Reaxys:238057
Wikipedia:Triaziquone
2,3,5-tris(aziridin-1-yl)-1,4-benzoquinone
FlyBase miscellaneous CV
chebi_ontology
1,1',1''-(3,6-Dioxo-1,4-cyclohexadiene-1,2,4-triyl)trisaziridine
2,3,5-Ethylenimine-1,4-benzoquinone
2,3,5-Tri(1-aziridinyl)-p-benzoquinone
2,3,5-Tri-(1-aziridinyl)-p-benzoquinone
2,3,5-Triethyleneimino-1,4-benzoquinone
2,3,5-Tris(1-aziridino)-p-benzoquinone
2,3,5-Tris(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione
2,3,5-Tris(1-aziridinyl)-p-benzoquinone
2,3,5-Tris(aziridino)-1,4-benzoquinone
2,3,5-Tris(ethyleneimino)-1,4-benzoquinone
2,3,5-Tris(ethylenimino)-1,4-benzoquinone
2,3,5-Tris(ethylenimino)-p-benzoquinone
2,3,5-Tris(ethylenimino)benzoquinone
2,3,5-Trisethyleneiminobenzoquinone
Triazichon
Triaziquonum
Triethyleneaminobenzoquinone
Tris(1-aziridinyl)-p-benzoquinone
Tris(aziridinyl)-p-benzoquinone
Tris(aziridinyl)-para-benzoquinone
Tris(ethyleneimino)benzoquinone
triazicuona
triaziquone
CHEBI:27090
triaziquone
CAS:68-76-8
ChemIDplus
CAS:68-76-8
KEGG COMPOUND
CAS:68-76-8
NIST Chemistry WebBook
Drug_Central:4372
DrugCentral
PMID:146335
Europe PMC
PMID:20371239
Europe PMC
PMID:362189
Europe PMC
PMID:3672382
Europe PMC
PMID:582920
Europe PMC
PMID:624547
Europe PMC
PMID:74416
Europe PMC
Reaxys:238057
Reaxys
2,3,5-tris(aziridin-1-yl)-1,4-benzoquinone
IUPAC
1,1',1''-(3,6-Dioxo-1,4-cyclohexadiene-1,2,4-triyl)trisaziridine
ChemIDplus
2,3,5-Ethylenimine-1,4-benzoquinone
NIST_Chemistry_WebBook
2,3,5-Tri(1-aziridinyl)-p-benzoquinone
NIST_Chemistry_WebBook
2,3,5-Tri-(1-aziridinyl)-p-benzoquinone
ChemIDplus
2,3,5-Triethyleneimino-1,4-benzoquinone
ChemIDplus
2,3,5-Tris(1-aziridino)-p-benzoquinone
ChemIDplus
2,3,5-Tris(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione
NIST_Chemistry_WebBook
2,3,5-Tris(1-aziridinyl)-p-benzoquinone
ChemIDplus
2,3,5-Tris(aziridino)-1,4-benzoquinone
ChemIDplus
2,3,5-Tris(ethyleneimino)-1,4-benzoquinone
ChemIDplus
2,3,5-Tris(ethylenimino)-1,4-benzoquinone
ChemIDplus
2,3,5-Tris(ethylenimino)-p-benzoquinone
ChemIDplus
2,3,5-Tris(ethylenimino)benzoquinone
ChemIDplus
2,3,5-Trisethyleneiminobenzoquinone
ChemIDplus
Triazichon
ChemIDplus
Triaziquonum
ChemIDplus
Triethyleneaminobenzoquinone
ChemIDplus
Tris(1-aziridinyl)-p-benzoquinone
ChemIDplus
Tris(aziridinyl)-p-benzoquinone
NIST_Chemistry_WebBook
Tris(aziridinyl)-para-benzoquinone
KEGG_COMPOUND
Tris(ethyleneimino)benzoquinone
ChemIDplus
triazicuona
ChemIDplus
triaziquone
KEGG_DRUG
triaziquone
WHO_MedNet
chebi_ontology
trimethylxanthines
CHEBI:27134
trimethylxanthine
trimethylxanthines
ChEBI
chebi_ontology
heterobicyclic compounds
organic heterobicyclic compounds
CHEBI:27171
organic heterobicyclic compound
heterobicyclic compounds
ChEBI
organic heterobicyclic compounds
ChEBI
A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.
chebi_ontology
univalent acyl group
univalent carboacyl groups
univalent carboxylic acyl groups
CHEBI:27207
univalent carboacyl group
univalent acyl group
ChEBI
univalent carboacyl groups
ChEBI
univalent carboxylic acyl groups
ChEBI
chebi_ontology
CHEBI:27242
uridines
0
C3H5NO2
InChI=1S/C3H5NO2/c1-2-6-3(4)5/h2H,1H2,(H2,4,5)
LVLANIHJQRZTPY-UHFFFAOYSA-N
87.07734
87.03203
NC(=O)OC=C
Beilstein:1921122
CAS:15805-73-9
vinyl carbamate
FlyBase miscellaneous CV
chebi_ontology
carbamic acid, vinyl ester
ethenyl carbamate
CHEBI:27292
vinyl carbamate
Beilstein:1921122
ChemIDplus
CAS:15805-73-9
ChemIDplus
vinyl carbamate
IUPAC
carbamic acid, vinyl ester
ChemIDplus
ethenyl carbamate
ChemIDplus
Any plant metabolite that is found naturally as a component of a volatile oil.
Wikipedia:Essential_oil
chebi_ontology
essential oil component
essential oil components
ethereal oil component
ethereal oil components
volatile oil components
CHEBI:27311
volatile oil component
essential oil component
ChEBI
essential oil components
ChEBI
ethereal oil component
ChEBI
ethereal oil components
ChEBI
volatile oil components
ChEBI
chebi_ontology
wasserloesliche Vitamine
water-soluble vitamins
CHEBI:27314
water-soluble vitamin
wasserloesliche Vitamine
ChEBI
water-soluble vitamins
ChEBI
A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
zwitterion
zwitterions
chebi_ontology
compose zwitterionique
compuestos zwitterionicos
zwitteriones
zwitterionic compounds
CHEBI:27369
zwitterion
zwitterion
IUPAC
zwitterions
IUPAC
compose zwitterionique
IUPAC
compuestos zwitterionicos
IUPAC
zwitteriones
IUPAC
zwitterionic compounds
IUPAC
An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl.
0
CH4O3S
InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)
AFVFQIVMOAPDHO-UHFFFAOYSA-N
96.10666
95.98812
CS(O)(=O)=O
CHEBI:6813
Beilstein:1446024
CAS:75-75-2
Gmelin:1681
KEGG:C11145
MetaCyc:CPD-3746
PMID:24304088
PMID:24593036
Reaxys:1446024
Wikipedia:Methanesulfonic_acid
Methanesulfonic acid
methanesulfonic acid
chebi_ontology
Methansulfonsaeure
methylsulfonic acid
CHEBI:27376
methanesulfonic acid
Beilstein:1446024
Beilstein
CAS:75-75-2
ChemIDplus
CAS:75-75-2
KEGG COMPOUND
CAS:75-75-2
NIST Chemistry WebBook
Gmelin:1681
Gmelin
PMID:24304088
Europe PMC
PMID:24593036
Europe PMC
Reaxys:1446024
Reaxys
Methanesulfonic acid
KEGG_COMPOUND
methanesulfonic acid
IUPAC
Methansulfonsaeure
ChEBI
methylsulfonic acid
NIST_Chemistry_WebBook
An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
0
C19H19N7O6
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
OVBPIULPVIDEAO-LBPRGKRZSA-N
441.39750
441.13968
Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1
CHEBI:24075
CHEBI:42610
CHEBI:5140
CHEBI:569217
Beilstein:100781
CAS:59-30-3
DrugBank:DB00158
Drug_Central:1231
KEGG:C00504
KEGG:D00070
KNApSAcK:C00001539
LINCS:LSM-5355
MetaCyc:CPD-12826
PDBeChem:FOL
PMID:11261364
PMID:11451208
PMID:14387833
PMID:15754725
PMID:17784727
PMID:18788725
PMID:19355913
PMID:24650098
PMID:9040515
Reaxys:100781
Wikipedia:Folic_Acid
FOLIC ACID
Folic acid
N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
chebi_ontology
Folate
Folsaeure
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-pteroyl-L-glutamic acid
PGA
PteGlu
Pteroylglutamic acid
pteroyl-L-glutamic acid
pteroyl-L-monoglutamic acid
vitamin Bc
vitamin M
CHEBI:27470
folic acid
Beilstein:100781
Beilstein
CAS:59-30-3
ChemIDplus
CAS:59-30-3
KEGG COMPOUND
CAS:59-30-3
NIST Chemistry WebBook
Drug_Central:1231
DrugCentral
PMID:11261364
Europe PMC
PMID:11451208
Europe PMC
PMID:14387833
Europe PMC
PMID:15754725
Europe PMC
PMID:17784727
Europe PMC
PMID:18788725
ChEMBL
PMID:19355913
Europe PMC
PMID:24650098
Europe PMC
PMID:9040515
Europe PMC
Reaxys:100781
Reaxys
FOLIC ACID
PDBeChem
Folic acid
KEGG_COMPOUND
N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
IUPAC
Folate
KEGG_COMPOUND
Folsaeure
ChEBI
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
PDBeChem
N-pteroyl-L-glutamic acid
ChEBI
PGA
NIST_Chemistry_WebBook
PteGlu
NIST_Chemistry_WebBook
Pteroylglutamic acid
KEGG_COMPOUND
pteroyl-L-glutamic acid
ChemIDplus
pteroyl-L-monoglutamic acid
ChemIDplus
vitamin Bc
ChemIDplus
vitamin M
ChemIDplus
0
C15H18N4O5
InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
NWIBSHFKIJFRCO-WUDYKRTCSA-N
334.32720
334.12772
[H][C@]12CN3C4=C([C@@H](COC(N)=O)[C@@]3(OC)[C@@]1([H])N2)C(=O)C(N)=C(C)C4=O
CHEBI:25356
CHEBI:6953
Beilstein:3570056
CAS:50-07-7
DrugBank:DB00305
Drug_Central:1819
KEGG:C06681
KEGG:D00208
KNApSAcK:C00018668
LINCS:LSM-6310
Wikipedia:Mitomycin
Mitomycin C
[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
FlyBase miscellaneous CV
chebi_ontology
7-Amino-9alpha-methoxymitosane
Ametycine
MMC
Mitocin-C
Mitomycin
Mutamycin
CHEBI:27504
mitomycin C
Beilstein:3570056
Beilstein
CAS:50-07-7
ChemIDplus
CAS:50-07-7
KEGG COMPOUND
Drug_Central:1819
DrugCentral
Mitomycin C
KEGG_COMPOUND
[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
IUPAC
7-Amino-9alpha-methoxymitosane
ChemIDplus
Ametycine
ChemIDplus
MMC
ChemIDplus
Mitocin-C
ChemIDplus
Mitomycin
KEGG_COMPOUND
Mutamycin
ChemIDplus
0
B
InChI=1S/B
ZOXJGFHDIHLPTG-UHFFFAOYSA-N
10.81100
11.00930
[B]
CHEBI:22915
CHEBI:3152
CAS:7440-42-8
KEGG:C06266
WebElements:B
boron
chebi_ontology
5B
B
Bor
Boron
boracium
bore
boro
boron
CHEBI:27560
boron atom
CAS:7440-42-8
ChemIDplus
CAS:7440-42-8
KEGG COMPOUND
boron
IUPAC
5B
IUPAC
B
KEGG_COMPOUND
Bor
ChEBI
Boron
KEGG_COMPOUND
boracium
ChEBI
bore
ChEBI
boro
ChEBI
boron
ChEBI
A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.
0
C2H4O
InChI=1S/C2H4O/c1-2-3-1/h1-2H2
IAYPIBMASNFSPL-UHFFFAOYSA-N
44.05256
44.02621
C1CO1
CHEBI:24001
CHEBI:4900
Beilstein:102378
CAS:75-21-8
Gmelin:676
HMDB:HMDB0031305
KEGG:C06548
KEGG:D03474
PMID:11437638
PMID:24313866
PMID:24882394
PMID:25005741
PMID:3932500
Reaxys:102378
UM-BBD_compID:c0527
Wikipedia:Oxirane
oxirane
FlyBase miscellaneous CV
chebi_ontology
1,2-Epoxyaethan
1,2-epoxyethane
Aethylenoxid
Amprolene
Anprolene
Anproline
Dihydrooxirene
Dimethylene oxide
ETO
Ethylene oxide
Oxacyclopropane
Oxane
Oxidoethane
Oxyfume
epoxyethane
ethene oxide
oxyde d'ethylene
CHEBI:27561
oxirane
Beilstein:102378
Beilstein
CAS:75-21-8
ChemIDplus
CAS:75-21-8
KEGG COMPOUND
CAS:75-21-8
NIST Chemistry WebBook
Gmelin:676
Gmelin
PMID:11437638
Europe PMC
PMID:24313866
Europe PMC
PMID:24882394
Europe PMC
PMID:25005741
Europe PMC
PMID:3932500
Europe PMC
Reaxys:102378
Reaxys
UM-BBD_compID:c0527
UM-BBD
oxirane
IUPAC
1,2-Epoxyaethan
ChemIDplus
1,2-epoxyethane
NIST_Chemistry_WebBook
Aethylenoxid
ChemIDplus
Amprolene
ChemIDplus
Anprolene
NIST_Chemistry_WebBook
Anproline
ChemIDplus
Dihydrooxirene
ChemIDplus
Dimethylene oxide
ChemIDplus
ETO
ChemIDplus
Ethylene oxide
KEGG_COMPOUND
Oxacyclopropane
ChemIDplus
Oxane
ChemIDplus
Oxidoethane
ChemIDplus
Oxyfume
ChEBI
epoxyethane
NIST_Chemistry_WebBook
ethene oxide
NIST_Chemistry_WebBook
oxyde d'ethylene
ChemIDplus
0
C
InChI=1S/C
OKTJSMMVPCPJKN-UHFFFAOYSA-N
12.01070
12.00000
[C]
CHEBI:23009
CHEBI:3399
CAS:7440-44-0
KEGG:C06265
WebElements:C
carbon
chebi_ontology
6C
C
Carbon
Kohlenstoff
carbon
carbone
carbonium
carbono
CHEBI:27594
carbon atom
CAS:7440-44-0
ChemIDplus
CAS:7440-44-0
KEGG COMPOUND
carbon
IUPAC
6C
IUPAC
C
IUPAC
C
KEGG_COMPOUND
Carbon
KEGG_COMPOUND
Kohlenstoff
ChEBI
carbon
ChEBI
carbone
ChEBI
carbonium
ChEBI
carbono
ChEBI
0
C62H86N12O16
InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
RJURFGZVJUQBHK-IIXSONLDSA-N
1255.41700
1254.62847
[H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C
CHEBI:22218
CHEBI:2446
Beilstein:4173766
CAS:50-76-0
DrugBank:DB00970
Drug_Central:774
KEGG:C06770
KEGG:D00214
LINCS:LSM-5783
Wikipedia:Dactinomycin
2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide
Actinomycin D
FlyBase miscellaneous CV
chebi_ontology
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
ActD
Dactinomycin
actinomycin C1
actinomycin IV
CHEBI:27666
actinomycin D
Beilstein:4173766
Beilstein
CAS:50-76-0
ChemIDplus
CAS:50-76-0
KEGG COMPOUND
Drug_Central:774
DrugCentral
2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide
IUPAC
Actinomycin D
KEGG_COMPOUND
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
ChemIDplus
ActD
ChEBI
Dactinomycin
KEGG_COMPOUND
actinomycin C1
ChEBI
actinomycin IV
ChemIDplus
A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
0
C8H10N4O2
InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
RYYVLZVUVIJVGH-UHFFFAOYSA-N
194.19076
194.08038
Cn1cnc2n(C)c(=O)n(C)c(=O)c12
CHEBI:22982
CHEBI:3295
CHEBI:41472
Beilstein:17705
CAS:58-08-2
DrugBank:DB00201
Drug_Central:463
Gmelin:103040
HMDB:HMDB0001847
KEGG:C07481
KEGG:D00528
KNApSAcK:C00001492
LINCS:LSM-2026
MetaCyc:1-3-7-TRIMETHYLXANTHINE
PDBeChem:CFF
PMID:10510174
PMID:10796597
PMID:10803761
PMID:10822912
PMID:10884512
PMID:10924888
PMID:10983026
PMID:11014293
PMID:11022879
PMID:11209966
PMID:11312039
PMID:11410911
PMID:11431501
PMID:11815511
PMID:11949272
PMID:12397877
PMID:12457274
PMID:12574990
PMID:12915014
PMID:12943586
PMID:14521986
PMID:14607010
PMID:15257305
PMID:15280431
PMID:15681408
PMID:15718055
PMID:15840517
PMID:16143823
PMID:16391865
PMID:16528931
PMID:16644114
PMID:16709440
PMID:16805851
PMID:16856769
PMID:17132260
PMID:17387608
PMID:17508167
PMID:17724925
PMID:17932622
PMID:17957400
PMID:18068204
PMID:18258404
PMID:18421070
PMID:18625110
PMID:18647558
PMID:19007524
PMID:19047957
PMID:19084078
PMID:19088793
PMID:19418355
PMID:19879252
PMID:20164568
PMID:20470411
PMID:22770225
PMID:7441110
PMID:7689104
PMID:8332255
PMID:8347173
PMID:8679661
PMID:9063686
PMID:9067318
PMID:9132918
PMID:9218278
Reaxys:17705
Wikipedia:Caffeine
1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
CAFFEINE
Caffeine
caffeine
FlyBase miscellaneous CV
chebi_ontology
1,3,7-Trimethylxanthine
1,3,7-trimethyl-2,6-dioxopurine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-methyltheobromine
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
7-methyltheophylline
Coffein
Koffein
Thein
anhydrous caffeine
cafeina
cafeine
guaranine
mateina
methyltheobromine
teina
theine
CHEBI:27732
caffeine
Beilstein:17705
Beilstein
CAS:58-08-2
ChemIDplus
CAS:58-08-2
KEGG COMPOUND
CAS:58-08-2
NIST Chemistry WebBook
Drug_Central:463
DrugCentral
Gmelin:103040
Gmelin
PMID:10510174
Europe PMC
PMID:10796597
Europe PMC
PMID:10803761
Europe PMC
PMID:10822912
Europe PMC
PMID:10884512
Europe PMC
PMID:10924888
Europe PMC
PMID:10983026
Europe PMC
PMID:11014293
Europe PMC
PMID:11022879
Europe PMC
PMID:11209966
Europe PMC
PMID:11312039
Europe PMC
PMID:11410911
Europe PMC
PMID:11431501
Europe PMC
PMID:11815511
Europe PMC
PMID:11949272
Europe PMC
PMID:12397877
Europe PMC
PMID:12457274
Europe PMC
PMID:12574990
Europe PMC
PMID:12915014
Europe PMC
PMID:12943586
Europe PMC
PMID:14521986
Europe PMC
PMID:14607010
Europe PMC
PMID:15257305
Europe PMC
PMID:15280431
Europe PMC
PMID:15681408
Europe PMC
PMID:15718055
Europe PMC
PMID:15840517
Europe PMC
PMID:16143823
Europe PMC
PMID:16391865
Europe PMC
PMID:16528931
Europe PMC
PMID:16644114
Europe PMC
PMID:16709440
Europe PMC
PMID:16805851
Europe PMC
PMID:16856769
Europe PMC
PMID:17132260
Europe PMC
PMID:17387608
Europe PMC
PMID:17508167
Europe PMC
PMID:17724925
Europe PMC
PMID:17932622
Europe PMC
PMID:17957400
Europe PMC
PMID:18068204
Europe PMC
PMID:18258404
Europe PMC
PMID:18421070
Europe PMC
PMID:18625110
Europe PMC
PMID:18647558
Europe PMC
PMID:19007524
Europe PMC
PMID:19047957
Europe PMC
PMID:19084078
Europe PMC
PMID:19088793
Europe PMC
PMID:19418355
Europe PMC
PMID:19879252
Europe PMC
PMID:20164568
Europe PMC
PMID:20470411
Europe PMC
PMID:22770225
Europe PMC
PMID:7441110
Europe PMC
PMID:7689104
Europe PMC
PMID:8332255
Europe PMC
PMID:8347173
Europe PMC
PMID:8679661
Europe PMC
PMID:9063686
Europe PMC
PMID:9067318
Europe PMC
PMID:9132918
Europe PMC
PMID:9218278
Europe PMC
Reaxys:17705
Reaxys
1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
IUPAC
CAFFEINE
PDBeChem
Caffeine
KEGG_COMPOUND
caffeine
UniProt
1,3,7-Trimethylxanthine
KEGG_COMPOUND
1,3,7-trimethyl-2,6-dioxopurine
ChemIDplus
1,3,7-trimethylpurine-2,6-dione
IUPHAR
1,3,7-trimethylxanthine
NIST_Chemistry_WebBook
1-methyltheobromine
ChemIDplus
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
NIST_Chemistry_WebBook
7-methyltheophylline
NIST_Chemistry_WebBook
Coffein
ChemIDplus
Koffein
ChemIDplus
Thein
ChemIDplus
anhydrous caffeine
KEGG_DRUG
cafeina
ChemIDplus
cafeine
ChEBI
guaranine
IUPHAR
mateina
ChemIDplus
methyltheobromine
IUPHAR
teina
ChEBI
theine
NIST_Chemistry_WebBook
A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
0
C2H4Cl2
InChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2
WSLDOOZREJYCGB-UHFFFAOYSA-N
98.95856
97.96901
ClCCCl
CHEBI:18881
CHEBI:49557
CHEBI:497
Beilstein:605264
CAS:107-06-2
DrugBank:DB03733
Gmelin:49272
HMDB:HMDB0029571
KEGG:C06752
MetaCyc:12-DICHLOROETHANE
PDBeChem:DCE
PMID:24228488
PMID:24329990
PMID:24441515
PPDB:2774
Reaxys:605264
UM-BBD_compID:c0001
Wikipedia:1,2-Dichloroethane
1,2-DICHLOROETHANE
1,2-Dichloroethane
1,2-dichloroethane
FlyBase miscellaneous CV
chebi_ontology
1,2-DCE
1,2-Dichloraethan
Aethylenchlorid
Aethylendichlorid
DCE
Dutch liquid
EDC
Ethylene dichloride
Glycol dichloride
alpha,beta-dichloroethane
ethane dichloride
ethylene chloride
CHEBI:27789
1,2-dichloroethane
Beilstein:605264
Beilstein
CAS:107-06-2
ChemIDplus
CAS:107-06-2
KEGG COMPOUND
CAS:107-06-2
NIST Chemistry WebBook
Gmelin:49272
Gmelin
PMID:24228488
Europe PMC
PMID:24329990
Europe PMC
PMID:24441515
Europe PMC
Reaxys:605264
Reaxys
UM-BBD_compID:c0001
UM-BBD
1,2-DICHLOROETHANE
PDBeChem
1,2-Dichloroethane
KEGG_COMPOUND
1,2-dichloroethane
IUPAC
1,2-dichloroethane
UniProt
1,2-DCE
NIST_Chemistry_WebBook
1,2-Dichloraethan
ChEBI
Aethylenchlorid
ChEBI
Aethylendichlorid
ChEBI
DCE
ChemIDplus
Dutch liquid
KEGG_COMPOUND
EDC
ChemIDplus
Ethylene dichloride
KEGG_COMPOUND
Glycol dichloride
KEGG_COMPOUND
alpha,beta-dichloroethane
NIST_Chemistry_WebBook
ethane dichloride
ChemIDplus
ethylene chloride
ChemIDplus
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
0
Cl2H6N2Pt
H6Cl2N2Pt
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
LXZZYRPGZAFOLE-UHFFFAOYSA-L
300.04452
298.95560
[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H]
CHEBI:23314
CHEBI:3722
CAS:15663-27-1
DrugBank:DB00515
Gmelin:2519
HMDB:HMDB0014656
KEGG:C06911
KEGG:D00275
MetaCyc:CPD0-1392
MolBase:25
PMID:10883661
PMID:12537968
PMID:12831510
PMID:12935404
PMID:16327988
PMID:18472761
PMID:1855275
PMID:23554447
PMID:23604226
PMID:23651576
Patent:DE2318020
Patent:DE2329485
Reaxys:11324567
Wikipedia:Cisplatin
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Cisplatin
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
FlyBase miscellaneous CV
chebi_ontology
Briplatin
CDDP
Cismaplat
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Platamine
Platinex
Platinol
Randa
[PtCl2(NH3)2]
cis-DDP
cis-Diamminedichloroplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloroplatinum
cis-diammineplatinum(II) dichloride
cis-dichlorodiammineplatinum(II)
cis-platin
cisplatin
cisplatine
cisplatino
cisplatinum
CHEBI:27899
cisplatin
CAS:15663-27-1
ChemIDplus
CAS:15663-27-1
KEGG COMPOUND
Gmelin:2519
Gmelin
PMID:10883661
Europe PMC
PMID:12537968
Europe PMC
PMID:12831510
Europe PMC
PMID:12935404
Europe PMC
PMID:16327988
Europe PMC
PMID:18472761
Europe PMC
PMID:1855275
Europe PMC
PMID:23554447
Europe PMC
PMID:23604226
Europe PMC
PMID:23651576
Europe PMC
Reaxys:11324567
Reaxys
(SP-4-2)-diamminedichloridoplatinum
IUPAC
(SP-4-2)-diamminedichloroplatinum
IUPAC
Cisplatin
KEGG_COMPOUND
cis-diamminedichloridoplatinum(II)
IUPAC
cis-diamminedichloroplatinum(II)
IUPAC
Briplatin
ChemIDplus
CDDP
KEGG_COMPOUND
Cismaplat
DrugBank
Lederplatin
DrugBank
Neoplatin
DrugBank
Peyrone's chloride
ChemIDplus
Peyrone's salt
ChEBI
Platamine
DrugBank
Platinex
DrugBank
Platinol
KEGG_DRUG
Randa
DrugBank
[PtCl2(NH3)2]
KEGG_COMPOUND
cis-DDP
ChemIDplus
cis-Diamminedichloroplatinum(II)
KEGG_COMPOUND
cis-[PtCl2(NH3)2]
MolBase
cis-diamminedichloroplatinum
ChemIDplus
cis-diammineplatinum(II) dichloride
ChemIDplus
cis-dichlorodiammineplatinum(II)
ChemIDplus
cis-platin
ChEBI
cisplatin
ChemIDplus
cisplatine
ChemIDplus
cisplatino
ChemIDplus
cisplatinum
ChemIDplus
0
C9H12N6
InChI=1S/C9H12N6/c1-2-13(1)7-10-8(14-3-4-14)12-9(11-7)15-5-6-15/h1-6H2
IUCJMVBFZDHPDX-UHFFFAOYSA-N
204.23202
204.11234
C1CN1c1nc(nc(n1)N1CC1)N1CC1
CHEBI:27109
CHEBI:9708
Beilstein:242245
CAS:51-18-3
Drug_Central:2739
KEGG:C07642
Reaxys:242245
2,4,6-tri(aziridin-1-yl)-1,3,5-triazine
tretamine
FlyBase miscellaneous CV
chebi_ontology
2,4,6-tri(1-aziridinyl)-1,3,5-triazine
2,4,6-tris(1-aziridinyl)-1,3,5-triazine
2,4,6-tris(1-aziridinyl)-s-triazine
2,4,6-tris(aziridin-1-yl)-1,3,5-triazine
TEM
Triethylenemelamine
Trisaziridinyltriazine
CHEBI:27919
tretamine
Beilstein:242245
Beilstein
CAS:51-18-3
ChemIDplus
CAS:51-18-3
KEGG COMPOUND
CAS:51-18-3
NIST Chemistry WebBook
Drug_Central:2739
DrugCentral
Reaxys:242245
Reaxys
2,4,6-tri(aziridin-1-yl)-1,3,5-triazine
IUPAC
tretamine
ChemIDplus
2,4,6-tri(1-aziridinyl)-1,3,5-triazine
NIST_Chemistry_WebBook
2,4,6-tris(1-aziridinyl)-1,3,5-triazine
NIST_Chemistry_WebBook
2,4,6-tris(1-aziridinyl)-s-triazine
NIST_Chemistry_WebBook
2,4,6-tris(aziridin-1-yl)-1,3,5-triazine
ChEBI
TEM
ChEBI
Triethylenemelamine
KEGG_COMPOUND
Trisaziridinyltriazine
KEGG_COMPOUND
An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.
0
C9H11NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
COLNVLDHVKWLRT-UHFFFAOYSA-N
165.18918
165.07898
NC(Cc1ccccc1)C(O)=O
CHEBI:25984
CHEBI:8089
Beilstein:1910407
CAS:150-30-1
Gmelin:50836
KEGG:C02057
PMID:17439666
PMID:22264337
Reaxys:1910407
Wikipedia:Phenylalanine
2-amino-3-phenylpropanoic acid
Phenylalanine
phenylalanine
chebi_ontology
DL-Phenylalanine
F
PHE
Phenylalanin
alpha-Amino-beta-phenylpropionic acid
fenilalanina
CHEBI:28044
phenylalanine
Beilstein:1910407
Beilstein
CAS:150-30-1
ChemIDplus
CAS:150-30-1
NIST Chemistry WebBook
Gmelin:50836
Gmelin
PMID:17439666
Europe PMC
PMID:22264337
Europe PMC
Reaxys:1910407
Reaxys
2-amino-3-phenylpropanoic acid
IUPAC
Phenylalanine
KEGG_COMPOUND
phenylalanine
ChEBI
phenylalanine
IUPAC
DL-Phenylalanine
KEGG_COMPOUND
F
ChEBI
PHE
ChEBI
Phenylalanin
ChEBI
alpha-Amino-beta-phenylpropionic acid
KEGG_COMPOUND
fenilalanina
ChEBI
A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position.
0
C16H14O6
InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1
AIONOLUJZLIMTK-AWEZNQCLSA-N
302.27880
302.07904
COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1
CHEBI:24529
CHEBI:5681
Beilstein:92705
CAS:520-33-2
DrugBank:DB01094
Drug_Central:1362
HMDB:HMDB0005782
KEGG:C01709
KNApSAcK:C00000968
LINCS:LSM-20933
LIPID_MAPS_instance:LMPK12140003
MetaCyc:CPD-7072
PMID:16964766
PMID:22409373
PMID:22794525
PMID:22899565
PMID:22903244
Reaxys:92705
Wikipedia:Hesperetin
(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
Hesperetin
hesperetin
chebi_ontology
(-)-(S)-hesperetin
(-)-hesperetin
(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
3',5,7-Trihydroxy-4'-methoxyflavanone
CHEBI:28230
hesperetin
Beilstein:92705
Beilstein
CAS:520-33-2
ChemIDplus
CAS:520-33-2
KEGG COMPOUND
Drug_Central:1362
DrugCentral
LIPID_MAPS_instance:LMPK12140003
LIPID MAPS
PMID:16964766
Europe PMC
PMID:22409373
Europe PMC
PMID:22794525
Europe PMC
PMID:22899565
Europe PMC
PMID:22903244
Europe PMC
Reaxys:92705
Reaxys
(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
IUPAC
Hesperetin
KEGG_COMPOUND
hesperetin
UniProt
(-)-(S)-hesperetin
ChEBI
(-)-hesperetin
ChEBI
(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
ChEBI
3',5,7-Trihydroxy-4'-methoxyflavanone
KEGG_COMPOUND
A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
0
C2H6OS
InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
78.13444
78.01394
CS(C)=O
CHEBI:23801
CHEBI:42138
CHEBI:4612
Beilstein:506008
CAS:67-68-5
DrugBank:DB01093
Drug_Central:906
Gmelin:1556
HMDB:HMDB0002151
KEGG:C11143
KEGG:D01043
LINCS:LSM-36361
PDBeChem:DMS
PMID:11162043
PMID:11350866
PMID:15237653
PMID:15588915
PMID:15868171
PMID:16434015
PMID:19096138
PMID:19382398
PMID:21426213
PMID:22030943
PMID:22722716
PMID:22768202
PMID:22814967
Reaxys:506008
UM-BBD_compID:c0236
Wikipedia:Dimethyl_Sulfoxide
(methanesulfinyl)methane
DIMETHYL SULFOXIDE
Dimethyl sulfoxide
dimethyl sulfoxide
FlyBase miscellaneous CV
chebi_ontology
(CH3)2SO
DMSO
Dimethylsulfoxid
S(O)Me2
dimethyl sulfoxide
dimethyl sulfur oxide
dimethyl sulphoxide
dimethyli sulfoxidum
dimethylsulfoxyde
dimetil sulfoxido
dmso
methylsulfinylmethane
sulfinylbis(methane)
CHEBI:28262
dimethyl sulfoxide
Beilstein:506008
Beilstein
CAS:67-68-5
ChemIDplus
CAS:67-68-5
KEGG COMPOUND
CAS:67-68-5
NIST Chemistry WebBook
Drug_Central:906
DrugCentral
Gmelin:1556
Gmelin
PMID:11162043
Europe PMC
PMID:11350866
Europe PMC
PMID:15237653
Europe PMC
PMID:15588915
Europe PMC
PMID:15868171
Europe PMC
PMID:16434015
Europe PMC
PMID:19096138
Europe PMC
PMID:19382398
Europe PMC
PMID:21426213
Europe PMC
PMID:22030943
Europe PMC
PMID:22722716
Europe PMC
PMID:22768202
Europe PMC
PMID:22814967
Europe PMC
Reaxys:506008
Reaxys
UM-BBD_compID:c0236
UM-BBD
(methanesulfinyl)methane
IUPAC
DIMETHYL SULFOXIDE
PDBeChem
Dimethyl sulfoxide
KEGG_COMPOUND
dimethyl sulfoxide
IUPAC
dimethyl sulfoxide
UniProt
(CH3)2SO
NIST_Chemistry_WebBook
DMSO
KEGG_COMPOUND
Dimethylsulfoxid
ChEBI
S(O)Me2
ChEBI
dimethyl sulfoxide
ChemIDplus
dimethyl sulfur oxide
NIST_Chemistry_WebBook
dimethyl sulphoxide
ChemIDplus
dimethyli sulfoxidum
ChemIDplus
dimethylsulfoxyde
ChemIDplus
dimetil sulfoxido
ChemIDplus
dmso
IUPAC
methylsulfinylmethane
ChemIDplus
sulfinylbis(methane)
ChemIDplus
A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae.
0
C2H4Br2
InChI=1S/C2H4Br2/c3-1-2-4/h1-2H2
PAAZPARNPHGIKF-UHFFFAOYSA-N
187.86116
185.86798
BrCCBr
CHEBI:18880
CHEBI:496
Beilstein:605266
CAS:106-93-4
Gmelin:1913
HMDB:HMDB0060334
KEGG:C11088
MetaCyc:12-DIBROMOETHANE
PMID:10088182
PMID:11312844
PPDB:1484
Reaxys:605266
Wikipedia:1,2-Dibromoethane
1,2-Dibromoethane
1,2-dibromoethane
FlyBase miscellaneous CV
chebi_ontology
DBE
EDB
Ethylene dibromide
alpha,beta-dibromoethane
alpha,omega-dibromoethane
ethylene bromide
sym-Dibromoethane
CHEBI:28534
1,2-dibromoethane
Beilstein:605266
Beilstein
CAS:106-93-4
ChemIDplus
CAS:106-93-4
KEGG COMPOUND
CAS:106-93-4
NIST Chemistry WebBook
Gmelin:1913
Gmelin
PMID:10088182
Europe PMC
PMID:11312844
Europe PMC
Reaxys:605266
Reaxys
1,2-Dibromoethane
KEGG_COMPOUND
1,2-dibromoethane
IUPAC
1,2-dibromoethane
UniProt
DBE
NIST_Chemistry_WebBook
EDB
NIST_Chemistry_WebBook
Ethylene dibromide
KEGG_COMPOUND
alpha,beta-dibromoethane
NIST_Chemistry_WebBook
alpha,omega-dibromoethane
ChemIDplus
ethylene bromide
NIST_Chemistry_WebBook
sym-Dibromoethane
ChemIDplus
A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised.
0
CH3NO2
InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)
KXDHJXZQYSOELW-UHFFFAOYSA-N
61.04006
61.01638
NC(O)=O
CHEBI:22504
CHEBI:23002
CHEBI:3386
CHEBI:44573
Beilstein:1734754
CAS:463-77-4
DrugBank:DB04261
Gmelin:130345
KEGG:C01563
PDBeChem:OUT
Wikipedia:Carbamic_acid
CARBAMIC ACID
Carbamic acid
carbamic acid
chebi_ontology
Aminoameisensaeure
Aminoformic acid
Carbamate
Carbamidsaeure
CHEBI:28616
carbamic acid
Beilstein:1734754
Beilstein
CAS:463-77-4
ChemIDplus
CAS:463-77-4
KEGG COMPOUND
Gmelin:130345
Gmelin
CARBAMIC ACID
PDBeChem
Carbamic acid
KEGG_COMPOUND
carbamic acid
IUPAC
Aminoameisensaeure
ChEBI
Aminoformic acid
KEGG_COMPOUND
Carbamate
KEGG_COMPOUND
Carbamidsaeure
ChEBI
0
P
InChI=1S/P
OAICVXFJPJFONN-UHFFFAOYSA-N
30.97376
30.97376
[P]
CHEBI:26080
CHEBI:8168
CAS:7723-14-0
Gmelin:16235
KEGG:C06262
WebElements:P
phosphorus
chebi_ontology
15P
P
Phosphor
Phosphorus
fosforo
phosphore
phosphorus
CHEBI:28659
phosphorus atom
CAS:7723-14-0
ChemIDplus
CAS:7723-14-0
KEGG COMPOUND
Gmelin:16235
Gmelin
phosphorus
IUPAC
15P
IUPAC
P
IUPAC
P
KEGG_COMPOUND
Phosphor
ChEBI
Phosphorus
KEGG_COMPOUND
fosforo
ChEBI
phosphore
ChEBI
phosphorus
ChEBI
0
Cu
InChI=1S/Cu
RYGMFSIKBFXOCR-UHFFFAOYSA-N
63.54600
62.92960
[Cu]
CHEBI:23376
CHEBI:3874
CAS:7440-50-8
Gmelin:16269
KEGG:C00070
WebElements:Cu
copper
chebi_ontology
29Cu
Copper
Cu
Kupfer
cobre
copper
cuivre
cuprum
CHEBI:28694
copper atom
CAS:7440-50-8
ChemIDplus
CAS:7440-50-8
KEGG COMPOUND
Gmelin:16269
Gmelin
copper
IUPAC
29Cu
IUPAC
Copper
KEGG_COMPOUND
Cu
ChEBI
Cu
IUPAC
Kupfer
ChEBI
cobre
ChEBI
copper
ChEBI
cuivre
ChEBI
cuprum
IUPAC
A metal fluoride salt with a Na(+) counterion.
0
FNa
Na.F
InChI=1S/FH.Na/h1H;/q;+1/p-1
PUZPDOWCWNUUKD-UHFFFAOYSA-M
41.98817
41.98817
[F-].[Na+]
CHEBI:26713
CHEBI:9178
CAS:7681-49-4
KEGG:C08142
KEGG:D00943
Wikipedia:Sodium_Fluoride
Sodium fluoride
sodium fluoride
FlyBase miscellaneous CV
chebi_ontology
NaF
CHEBI:28741
sodium fluoride
CAS:7681-49-4
ChemIDplus
CAS:7681-49-4
KEGG COMPOUND
Sodium fluoride
KEGG_COMPOUND
sodium fluoride
IUPAC
NaF
IUPAC
A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
0
C28H34O15
InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
QUQPHWDTPGMPEX-QJBIFVCTSA-N
610.56056
610.18977
COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1
CHEBI:24530
CHEBI:5682
Beilstein:75140
CAS:520-26-3
DrugBank:DB04703
HMDB:HMDB0003265
KEGG:C09755
KEGG:D01038
KNApSAcK:C00000970
LINCS:LSM-2858
MetaCyc:CPD-7075
Reaxys:75140
Wikipedia:Hesperidin
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
Hesperidin
hesperidin
FlyBase miscellaneous CV
chebi_ontology
(S)-(-)-hesperidin
Cirantin
Ciratin
Hesperetin 7-O-rutinoside
Hesperidoside
CHEBI:28775
hesperidin
Beilstein:75140
Beilstein
CAS:520-26-3
ChemIDplus
CAS:520-26-3
KEGG COMPOUND
Reaxys:75140
Reaxys
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
IUPAC
Hesperidin
KEGG_COMPOUND
hesperidin
UniProt
(S)-(-)-hesperidin
ChemIDplus
Cirantin
ChemIDplus
Ciratin
KEGG_COMPOUND
Hesperetin 7-O-rutinoside
KEGG_COMPOUND
Hesperidoside
ChemIDplus
A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
0
C14H19Cl2NO2
InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
JCKYGMPEJWAADB-UHFFFAOYSA-N
304.21160
303.07928
OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl
CHEBI:25817
CHEBI:3601
CHEBI:48770
Beilstein:999011
CAS:305-03-3
DrugBank:DB00291
Drug_Central:588
KEGG:D00266
LINCS:LSM-2645
PDBeChem:CBL
PMID:22025197
PMID:22978684
PMID:23233721
PMID:23295789
PMID:23521128
PMID:23665800
PMID:23667729
PMID:23683018
PMID:23725434
PMID:23822827
PMID:24098639
PMID:24147900
PMID:24223689
Reaxys:999011
Wikipedia:Chlorambucil
4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
CHLORAMBUCIL
Chlorambucil
FlyBase miscellaneous CV
chebi_ontology
4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid
4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
Ambochlorin
Leukeran
N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid
chloraminophen
gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid
phenylbutyric acid nitrogen mustard
CHEBI:28830
chlorambucil
Beilstein:999011
Beilstein
CAS:305-03-3
ChemIDplus
CAS:305-03-3
NIST Chemistry WebBook
Drug_Central:588
DrugCentral
PMID:22025197
Europe PMC
PMID:22978684
Europe PMC
PMID:23233721
Europe PMC
PMID:23295789
Europe PMC
PMID:23521128
Europe PMC
PMID:23665800
Europe PMC
PMID:23667729
Europe PMC
PMID:23683018
Europe PMC
PMID:23725434
Europe PMC
PMID:23822827
Europe PMC
PMID:24098639
Europe PMC
PMID:24147900
Europe PMC
PMID:24223689
Europe PMC
Reaxys:999011
Reaxys
4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
IUPAC
CHLORAMBUCIL
PDBeChem
Chlorambucil
KEGG_DRUG
4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid
NIST_Chemistry_WebBook
4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
NIST_Chemistry_WebBook
Ambochlorin
NIST_Chemistry_WebBook
Leukeran
NIST_Chemistry_WebBook
N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid
NIST_Chemistry_WebBook
chloraminophen
ChemIDplus
gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid
NIST_Chemistry_WebBook
phenylbutyric acid nitrogen mustard
ChemIDplus
Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives.
0
C15H2O2R10
214.176
214.00548
O1C2=C(C(C(C1C3=C(C(=C(C(=C3*)*)*)*)*)*)=O)C(=C(C(=C2*)*)*)*
CHEBI:13636
CHEBI:24038
CHEBI:24054
MetaCyc:FLAVANONES
Wikipedia:Flavanone
chebi_ontology
2,3-dihydroflavones
a flavanone
CHEBI:28863
flavanones
2,3-dihydroflavones
ChEBI
a flavanone
UniProt
The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.
-1
CO2R
44.00950
43.98983
[O-]C([*])=O
CHEBI:13634
CHEBI:24022
CHEBI:4985
KEGG:C02403
PMID:18628202
Fatty acid anion
chebi_ontology
Alkanate
Fettsaeureanion
Fettsaeureanionen
a fatty acid
acido graso anionico
acidos grasos anionicos
anion de l'acide gras
fatty acid anions
CHEBI:28868
fatty acid anion
PMID:18628202
Europe PMC
Fatty acid anion
KEGG_COMPOUND
Alkanate
KEGG_COMPOUND
Fettsaeureanion
ChEBI
Fettsaeureanionen
ChEBI
a fatty acid
UniProt
acido graso anionico
ChEBI
acidos grasos anionicos
ChEBI
anion de l'acide gras
ChEBI
fatty acid anions
ChEBI
A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
0
C13H18Cl2N2O2
InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1
SGDBTWWWUNNDEQ-LBPRGKRZSA-N
305.20000
304.07453
N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O
CHEBI:25815
CHEBI:6742
CAS:148-82-3
DrugBank:DB01042
Drug_Central:1678
KEGG:D00369
PMID:10820424
PMID:10937717
PMID:11680815
PMID:11914777
PMID:18481314
PMID:445303
PMID:7494795
PMID:7605343
PMID:8552138
PMID:8951232
PMID:9218926
PMID:9250538
Patent:US108552
Patent:US275057
Patent:US3032584
Patent:US3032585
Reaxys:2816456
Wikipedia:Melphalan
4-[bis(2-chloroethyl)amino]-L-phenylalanine
FlyBase miscellaneous CV
chebi_ontology
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine
4-(Bis(2-chloroethyl)amino)-L-phenylalanine
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
L-PAM
L-Phenylalanine mustard
L-Sarcolysine
Phenylalanine mustard
Phenylalanine nitrogen mustard
melfalano
melphalan
melphalanum
p-Bis(beta-chloroethyl)aminophenylalanine
p-Di-(2-chloroethyl)amino-L-phenylalanine
p-L-Sarcolysin
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
p-N-Bis(2-chloroethyl)amino-L-phenylalanine
CHEBI:28876
melphalan
CAS:148-82-3
ChemIDplus
CAS:148-82-3
KEGG DRUG
Drug_Central:1678
DrugCentral
PMID:10820424
Europe PMC
PMID:10937717
Europe PMC
PMID:11680815
Europe PMC
PMID:11914777
Europe PMC
PMID:18481314
Europe PMC
PMID:445303
Europe PMC
PMID:7494795
Europe PMC
PMID:7605343
Europe PMC
PMID:8552138
Europe PMC
PMID:8951232
Europe PMC
PMID:9218926
Europe PMC
PMID:9250538
Europe PMC
Reaxys:2816456
Reaxys
4-[bis(2-chloroethyl)amino]-L-phenylalanine
IUPAC
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
ChemIDplus
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine
ChemIDplus
4-(Bis(2-chloroethyl)amino)-L-phenylalanine
ChemIDplus
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
ChemIDplus
L-PAM
ChemIDplus
L-Phenylalanine mustard
ChemIDplus
L-Sarcolysine
ChemIDplus
Phenylalanine mustard
ChemIDplus
Phenylalanine nitrogen mustard
ChemIDplus
melfalano
ChemIDplus
melphalan
KEGG_DRUG
melphalanum
ChemIDplus
p-Bis(beta-chloroethyl)aminophenylalanine
ChemIDplus
p-Di-(2-chloroethyl)amino-L-phenylalanine
ChemIDplus
p-L-Sarcolysin
ChemIDplus
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
ChEBI
p-N-Bis(2-chloroethyl)amino-L-phenylalanine
ChemIDplus
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
0
C6H14O6S2
InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3
COVZYZSDYWQREU-UHFFFAOYSA-N
246.30200
246.02318
CS(=O)(=O)OCCCCOS(C)(=O)=O
CHEBI:18936
CHEBI:3225
Beilstein:1791786
CAS:55-98-1
DrugBank:DB01008
Drug_Central:438
KEGG:C06862
KEGG:D00248
LINCS:LSM-5388
PMID:10523796
PMID:19361744
PMID:19611402
Patent:US2917432
Reaxys:1791786
Wikipedia:Busulfan
Busulfan
butane-1,4-diyl dimethanesulfonate
FlyBase miscellaneous CV
chebi_ontology
1,4-Bis(methanesulfonoxy)butane
1,4-Butanediol dimethanesulfonate
1,4-Dimesyloxybutane
1,4-Dimethanesulfonoxybutane
Bisulfex
Leucosulfan
Mablin
Mielucin
Misulban
Mitostan
Myeloleukon
Myleran
Tetramethylene bis(methanesulfonate)
busulfan
busulfano
busulfanum
CHEBI:28901
busulfan
Beilstein:1791786
Beilstein
CAS:55-98-1
ChemIDplus
CAS:55-98-1
KEGG DRUG
Drug_Central:438
DrugCentral
PMID:10523796
Europe PMC
PMID:19361744
Europe PMC
PMID:19611402
Europe PMC
Reaxys:1791786
Reaxys
Busulfan
KEGG_DRUG
butane-1,4-diyl dimethanesulfonate
IUPAC
1,4-Bis(methanesulfonoxy)butane
ChemIDplus
1,4-Butanediol dimethanesulfonate
ChemIDplus
1,4-Dimesyloxybutane
ChemIDplus
1,4-Dimethanesulfonoxybutane
ChemIDplus
Bisulfex
ChEBI
Leucosulfan
ChEBI
Mablin
ChEBI
Mielucin
ChEBI
Misulban
ChEBI
Mitostan
ChEBI
Myeloleukon
ChEBI
Myleran
KEGG_DRUG
Tetramethylene bis(methanesulfonate)
ChemIDplus
busulfan
WHO_MedNet
busulfano
WHO_MedNet
busulfanum
WHO_MedNet
An onium cation obtained by protonation of ammonia.
+1
H4N
InChI=1S/H3N/h1H3/p+1
QGZKDVFQNNGYKY-UHFFFAOYSA-O
18.03850
18.03383
[H][N+]([H])([H])[H]
CHEBI:22534
CHEBI:49783
CHEBI:7435
CAS:14798-03-9
Gmelin:84
KEGG:C01342
MetaCyc:AMMONIUM
MolBase:929
PDBeChem:NH4
PMID:11319011
PMID:11341317
PMID:12096804
PMID:14512268
PMID:14879753
PMID:16345391
PMID:16903292
PMID:17392693
PMID:18515490
PMID:19199063
PMID:19596600
PMID:19682559
PMID:19716251
PMID:21993530
PMID:22265469
PMID:22524020
PMID:22562341
PMID:22631217
Reaxys:16093784
Wikipedia:Ammonium
ammonium
azanium
chebi_ontology
AMMONIUM ION
Ammonium(1+)
NH4(+)
NH4+
[NH4](+)
CHEBI:28938
ammonium
CAS:14798-03-9
ChemIDplus
CAS:14798-03-9
NIST Chemistry WebBook
Gmelin:84
Gmelin
PMID:11319011
Europe PMC
PMID:11341317
Europe PMC
PMID:12096804
Europe PMC
PMID:14512268
Europe PMC
PMID:14879753
Europe PMC
PMID:16345391
Europe PMC
PMID:16903292
Europe PMC
PMID:17392693
Europe PMC
PMID:18515490
Europe PMC
PMID:19199063
Europe PMC
PMID:19596600
Europe PMC
PMID:19682559
Europe PMC
PMID:19716251
Europe PMC
PMID:21993530
Europe PMC
PMID:22265469
Europe PMC
PMID:22524020
Europe PMC
PMID:22562341
Europe PMC
PMID:22631217
Europe PMC
Reaxys:16093784
Reaxys
ammonium
ChEBI
ammonium
IUPAC
azanium
IUPAC
AMMONIUM ION
PDBeChem
Ammonium(1+)
ChemIDplus
NH4(+)
IUPAC
NH4(+)
UniProt
NH4+
KEGG_COMPOUND
[NH4](+)
MolBase
+1
C21H20NO4
InChI=1S/C21H19NO4/c1-22-11-13-8-19(25-3)20(26-4)9-15(13)14-6-5-12-7-17(23)18(24-2)10-16(12)21(14)22/h5-11H,1-4H3/p+1
OOKZVPUCASIEBL-UHFFFAOYSA-O
350.38784
350.13868
COc1cc2c(ccc3c4cc(OC)c(OC)cc4c[n+](C)c23)cc1O
CHEBI:24011
CHEBI:4968
CAS:52259-65-1
KEGG:C09438
KNApSAcK:C00001857
2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridinium
Fagaronine
FlyBase miscellaneous CV
chebi_ontology
CHEBI:28954
fagaronine
CAS:52259-65-1
KEGG COMPOUND
2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridinium
IUPAC
Fagaronine
KEGG_COMPOUND
A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid.
-2
C2O4R
88.019
87.97966
[O-]C(=O)[*]C([O-])=O
CHEBI:13632
CHEBI:23688
CHEBI:23689
CHEBI:38711
dicarboxylic acid dianion
chebi_ontology
a dicarboxylate
dicarboxylate
dicarboxylates
dicarboxylic acid dianions
CHEBI:28965
dicarboxylic acid dianion
dicarboxylic acid dianion
ChEBI
a dicarboxylate
UniProt
dicarboxylate
ChEBI
dicarboxylates
ChEBI
dicarboxylic acid dianions
ChEBI
0
CH2O3
InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)
BVKZGUZCCUSVTD-UHFFFAOYSA-N
62.02478
62.00039
OC(O)=O
CHEBI:13351
CHEBI:23017
CHEBI:23744
CHEBI:3401
CAS:463-79-6
Gmelin:25554
KEGG:C01353
PDBeChem:CO3
Carbonic acid
carbonic acid
dihydroxidooxidocarbon
chebi_ontology
Dihydrogen carbonate
H2CO3
Koehlensaeure
[CO(OH)2]
CHEBI:28976
carbonic acid
CAS:463-79-6
ChemIDplus
CAS:463-79-6
KEGG COMPOUND
Gmelin:25554
Gmelin
Carbonic acid
KEGG_COMPOUND
carbonic acid
IUPAC
dihydroxidooxidocarbon
IUPAC
Dihydrogen carbonate
KEGG_COMPOUND
H2CO3
IUPAC
H2CO3
KEGG_COMPOUND
Koehlensaeure
ChEBI
[CO(OH)2]
IUPAC
An ion of copper carrying a double positive charge.
+2
Cu
InChI=1S/Cu/q+2
JPVYNHNXODAKFH-UHFFFAOYSA-N
63.54600
62.92850
[Cu++]
CHEBI:20882
CHEBI:23380
CHEBI:49550
CAS:15158-11-9
Gmelin:6855
PDBeChem:CU
PMID:23900424
PMID:24168430
Reaxys:3587177
copper(2+)
copper(2+) ion
copper(II) cation
chebi_ontology
COPPER (II) ION
Cu(2+)
Cu(II)
Cu2+
copper(II) cation
copper, ion (Cu2+)
cupric ion
CHEBI:29036
copper(2+)
CAS:15158-11-9
ChemIDplus
Gmelin:6855
Gmelin
PMID:23900424
Europe PMC
PMID:24168430
Europe PMC
Reaxys:3587177
Reaxys
copper(2+)
IUPAC
copper(2+) ion
IUPAC
copper(II) cation
IUPAC
COPPER (II) ION
PDBeChem
Cu(2+)
UniProt
Cu(II)
ChEBI
Cu2+
ChEBI
copper(II) cation
ChEBI
copper, ion (Cu2+)
ChemIDplus
cupric ion
ChEBI
The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
-1
CO2R
44.00950
43.98983
[O-]C([*])=O
CHEBI:13626
CHEBI:13945
CHEBI:23026
CHEBI:58657
chebi_ontology
a carboxylate
carboxylic acid anions
carboxylic anions
CHEBI:29067
carboxylic acid anion
a carboxylate
UniProt
carboxylic acid anions
ChEBI
carboxylic anions
ChEBI
A monoatomic monocation obtained from sodium.
+1
Na
InChI=1S/Na/q+1
FKNQFGJONOIPTF-UHFFFAOYSA-N
22.98977
22.98922
[Na+]
CHEBI:26717
CHEBI:49766
CHEBI:9175
CAS:17341-25-2
Gmelin:15196
KEGG:C01330
PDBeChem:NA
sodium cation
sodium(1+)
sodium(1+) ion
sodium(I) cation
chebi_ontology
Na(+)
Na+
SODIUM ION
CHEBI:29101
sodium(1+)
CAS:17341-25-2
ChemIDplus
CAS:17341-25-2
NIST Chemistry WebBook
Gmelin:15196
Gmelin
sodium cation
IUPAC
sodium(1+)
IUPAC
sodium(1+) ion
IUPAC
sodium(I) cation
IUPAC
Na(+)
IUPAC
Na(+)
UniProt
Na+
KEGG_COMPOUND
SODIUM ION
PDBeChem
0
H2O3S
InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)
BDHFUVZGWQCTTF-UHFFFAOYSA-N
82.08008
81.97247
[H]S(O)(=O)=O
Gmelin:1404640
hydridohydroxidodioxidosulfur
sulfonic acid
chebi_ontology
HSHO3
Sulfonsaeure
[SHO2(OH)]
acide sulfonique
sulphonic acid
CHEBI:29214
sulfonic acid
Gmelin:1404640
Gmelin
hydridohydroxidodioxidosulfur
IUPAC
sulfonic acid
IUPAC
HSHO3
IUPAC
Sulfonsaeure
ChEBI
[SHO2(OH)]
IUPAC
acide sulfonique
ChEBI
sulphonic acid
ChEBI
A diatomic molecule containing covalently bonded hydrogen and fluorine atoms.
0
FH
InChI=1S/FH/h1H
KRHYYFGTRYWZRS-UHFFFAOYSA-N
20.00634
20.00623
F[H]
CAS:7664-39-3
Drug_Central:4499
Gmelin:166
KEGG:C16487
Hydrogen fluoride
fluorane
fluoridohydrogen
hydrogen fluoride
chebi_ontology
Fluoride
Fluorwasserstoff
HF
Hydrogenfluorid
[HF]
fluorure d'hydrogene
hydrofluoric acid
CHEBI:29228
hydrogen fluoride
CAS:7664-39-3
ChemIDplus
CAS:7664-39-3
KEGG COMPOUND
CAS:7664-39-3
NIST Chemistry WebBook
Drug_Central:4499
DrugCentral
Gmelin:166
Gmelin
Hydrogen fluoride
KEGG_COMPOUND
fluorane
IUPAC
fluoridohydrogen
IUPAC
hydrogen fluoride
IUPAC
Fluoride
KEGG_COMPOUND
Fluorwasserstoff
ChEBI
HF
IUPAC
Hydrogenfluorid
ChEBI
[HF]
IUPAC
fluorure d'hydrogene
ChEBI
hydrofluoric acid
ChemIDplus
-1
BH2O3
InChI=1S/BH2O3/c2-1(3)4/h2-3H/q-1
URSLCTBXQMKCFE-UHFFFAOYSA-N
60.82508
61.01025
[H]OB([O-])O[H]
Gmelin:49252
dihydrogen(trioxidoborate)(1-)
dihydrogenborate
dihydroxidooxidoborate(1-)
chebi_ontology
H2BO3(-)
[BO(OH)2](-)
CHEBI:29254
dihydrogenborate
Gmelin:49252
Gmelin
dihydrogen(trioxidoborate)(1-)
IUPAC
dihydrogenborate
IUPAC
dihydroxidooxidoborate(1-)
IUPAC
H2BO3(-)
IUPAC
[BO(OH)2](-)
IUPAC
-2
BHO3
InChI=1S/BHO3/c2-1(3)4/h2H/q-2
JSSGFLRDNVXLHY-UHFFFAOYSA-N
59.81714
60.00297
[H]OB([O-])[O-]
Gmelin:674511
hydrogen(trioxidoborate)(2-)
hydrogenborate
hydroxidodioxidoborate(2-)
chebi_ontology
HBO3(2-)
[BO2(OH)](2-)
CHEBI:29255
hydrogenborate
Gmelin:674511
Gmelin
hydrogen(trioxidoborate)(2-)
IUPAC
hydrogenborate
IUPAC
hydroxidodioxidoborate(2-)
IUPAC
HBO3(2-)
IUPAC
[BO2(OH)](2-)
IUPAC
CHEBI:13810
CHEBI:22325
CHEBI:2583
chebi_ontology
alkyl sulfates
CHEBI:29281
alkyl sulfate
alkyl sulfates
ChEBI
-1
H2N
InChI=1S/H2N/h1H2/q-1
HYGWNUKOUCZBND-UHFFFAOYSA-N
16.02262
16.01927
[H][N-][H]
amide
azanide
dihydridonitrate(1-)
chebi_ontology
NH2(-)
CHEBI:29337
azanide
amide
IUPAC
azanide
IUPAC
dihydridonitrate(1-)
IUPAC
NH2(-)
IUPAC
A divalent inorganic anion resulting from the removal of two protons from ammonia.
-2
HN
InChI=1S/HN/h1H/q-2
DZQYTNGKSBCIOE-UHFFFAOYSA-N
15.01468
15.01200
[N--][H]
azanediide
hydridonitrate(2-)
chebi_ontology
NH(2-)
imide
CHEBI:29340
hydridonitrate(2-)
azanediide
IUPAC
hydridonitrate(2-)
IUPAC
NH(2-)
IUPAC
imide
IUPAC
A carboxamide derived from a monocarboxylic acid.
0
CNOR3
42.01680
41.99799
[*]N([*])C([*])=O
CHEBI:13211
CHEBI:22207
CHEBI:25383
CHEBI:6977
chebi_ontology
monocarboxylic acid amides
CHEBI:29347
monocarboxylic acid amide
monocarboxylic acid amides
ChEBI
0
NO2
46.00550
45.99290
nitro
chebi_ontology
-NO2
CHEBI:29785
nitro group
nitro
IUPAC
-NO2
IUPAC
An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
0
C20H12
InChI=1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H
FMMWHPNWAFZXNH-UHFFFAOYSA-N
252.30928
252.09390
c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34
CHEBI:22716
CHEBI:3045
Beilstein:1911333
CAS:50-32-8
Gmelin:262573
KEGG:C07535
LINCS:LSM-2198
PMID:11932001
PMID:16256111
PMID:16381670
PMID:1844333
PMID:26530167
PMID:26703252
PMID:7561049
PMID:7721048
Reaxys:1911333
Wikipedia:Benzo(a)pyrene
Benzo[a]pyrene
benzo[pqr]tetraphene
FlyBase miscellaneous CV
chebi_ontology
(B(a)P)
3,4-BP
3,4-Benzopyrene
3,4-Benzpyrene
BP
Benzo(a)pyrene
Benzpyrene
benzo[def]chrysene
CHEBI:29865
benzo[a]pyrene
Beilstein:1911333
Beilstein
CAS:50-32-8
ChemIDplus
CAS:50-32-8
KEGG COMPOUND
CAS:50-32-8
NIST Chemistry WebBook
Gmelin:262573
Gmelin
PMID:11932001
Europe PMC
PMID:16256111
Europe PMC
PMID:16381670
Europe PMC
PMID:1844333
Europe PMC
PMID:26530167
Europe PMC
PMID:26703252
Europe PMC
PMID:7561049
Europe PMC
PMID:7721048
Europe PMC
Reaxys:1911333
Reaxys
Benzo[a]pyrene
KEGG_COMPOUND
benzo[pqr]tetraphene
IUPAC
(B(a)P)
ChEBI
3,4-BP
NIST_Chemistry_WebBook
3,4-Benzopyrene
NIST_Chemistry_WebBook
3,4-Benzpyrene
NIST_Chemistry_WebBook
BP
NIST_Chemistry_WebBook
Benzo(a)pyrene
ChemIDplus
Benzpyrene
KEGG_COMPOUND
benzo[def]chrysene
ChEBI
0
HO3S
81.07214
80.96464
PDBeChem:SFO
SULFO GROUP
hydroxydioxo-lambda(6)-sulfanyl
hydroxysulfonyl
sulfo
chebi_ontology
-S(O)2(OH)
CHEBI:29922
sulfo group
SULFO GROUP
PDBeChem
hydroxydioxo-lambda(6)-sulfanyl
IUPAC
hydroxysulfonyl
IUPAC
sulfo
IUPAC
-S(O)2(OH)
IUPAC
An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group
-1
C5H8NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1
WHUUTDBJXJRKMK-VKHMYHEASA-M
146.12136
146.04588
[NH3+][C@@H](CCC([O-])=O)C([O-])=O
CHEBI:13107
CHEBI:21301
CAS:11070-68-1
Gmelin:936654
MetaCyc:GLT
L-glutamate(1-)
hydrogen L-glutamate
chebi_ontology
(2S)-2-ammoniopentanedioate
L-glutamate
L-glutamic acid monoanion
L-glutamic acid, ion(1-)
CHEBI:29985
L-glutamate(1-)
CAS:11070-68-1
ChemIDplus
Gmelin:936654
Gmelin
L-glutamate(1-)
JCBN
hydrogen L-glutamate
IUPAC
(2S)-2-ammoniopentanedioate
IUPAC
L-glutamate
ChEBI
L-glutamate
UniProt
L-glutamic acid monoanion
JCBN
L-glutamic acid, ion(1-)
ChemIDplus
An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group
-1
C5H8NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1
WHUUTDBJXJRKMK-GSVOUGTGSA-M
146.12136
146.04588
[NH3+][C@H](CCC([O-])=O)C([O-])=O
CHEBI:12979
CHEBI:21022
Beilstein:8319427
MetaCyc:D-GLT
D-glutamate(1-)
hydrogen D-glutamate
chebi_ontology
(2R)-2-ammoniopentanedioate
D-glutamate
D-glutamic acid monoanion
CHEBI:29986
D-glutamate(1-)
Beilstein:8319427
Beilstein
D-glutamate(1-)
JCBN
hydrogen D-glutamate
IUPAC
(2R)-2-ammoniopentanedioate
IUPAC
D-glutamate
UniProt
D-glutamic acid monoanion
JCBN
A dicarboxylic acid dianion that is the conjugate base of glutamate(1-).
-2
C5H7NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2
WHUUTDBJXJRKMK-UHFFFAOYSA-L
145.11342
145.03860
NC(CCC([O-])=O)C([O-])=O
Beilstein:4134100
Gmelin:327903
Reaxys:4134100
2-aminopentanedioate
glutamate
glutamate(2-)
chebi_ontology
glutamic acid dianion
CHEBI:29987
glutamate(2-)
Beilstein:4134100
Beilstein
Gmelin:327903
Gmelin
Reaxys:4134100
Reaxys
2-aminopentanedioate
IUPAC
glutamate
IUPAC
glutamate(2-)
JCBN
glutamic acid dianion
JCBN
An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid.
-2
C5H7NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m0/s1
WHUUTDBJXJRKMK-VKHMYHEASA-L
145.11342
145.03860
N[C@@H](CCC([O-])=O)C([O-])=O
Gmelin:327905
(2S)-2-aminopentanedioate
L-glutamate
L-glutamate(2-)
chebi_ontology
L-glutamic acid dianion
CHEBI:29988
L-glutamate(2-)
Gmelin:327905
Gmelin
(2S)-2-aminopentanedioate
IUPAC
L-glutamate
IUPAC
L-glutamate(2-)
JCBN
L-glutamic acid dianion
JCBN
-2
C5H7NO4
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m1/s1
WHUUTDBJXJRKMK-GSVOUGTGSA-L
145.11342
145.03860
N[C@H](CCC([O-])=O)C([O-])=O
Beilstein:8143000
Gmelin:327904
(2R)-2-aminopentanedioate
D-glutamate
D-glutamate(2-)
chebi_ontology
D-glutamic acid dianion
CHEBI:29989
D-glutamate(2-)
Beilstein:8143000
Beilstein
Gmelin:327904
Gmelin
(2R)-2-aminopentanedioate
IUPAC
D-glutamate
IUPAC
D-glutamate(2-)
JCBN
D-glutamic acid dianion
JCBN
+1
CH6N3
InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)/p+1
ZRALSGWEFCBTJO-UHFFFAOYSA-O
60.07856
60.05562
NC(N)=[NH2+]
Beilstein:1902006
Gmelin:239627
guanidinium
chebi_ontology
[C(NH2)3](+)
diaminomethaniminium
guanidine
CHEBI:30087
guanidinium
Beilstein:1902006
Beilstein
Gmelin:239627
Gmelin
guanidinium
IUPAC
[C(NH2)3](+)
ChEBI
diaminomethaniminium
IUPAC
guanidine
UniProt
+2
0.00000
[*++]
CHEBI:23856
CHEBI:4665
KEGG:C00572
chebi_ontology
Divalent cation
divalent inorganic cations
monoatomic dications
CHEBI:30412
monoatomic dication
Divalent cation
KEGG_COMPOUND
divalent inorganic cations
ChEBI
monoatomic dications
ChEBI
The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
0
CH2O2
InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)
BDAGIHXWWSANSR-UHFFFAOYSA-N
46.02538
46.00548
[H]C(O)=O
CHEBI:24082
CHEBI:42460
CHEBI:5145
BPDB:1749
Beilstein:1209246
CAS:64-18-6
DrugBank:DB01942
Gmelin:1008
HMDB:HMDB0000142
KEGG:C00058
KNApSAcK:C00001182
LIPID_MAPS_instance:LMFA01010040
MetaCyc:FORMATE
PDBeChem:FMT
PMID:12591956
PMID:14637377
PMID:15811469
PMID:16120414
PMID:16185830
PMID:16222862
PMID:16230297
PMID:16445901
PMID:16465784
PMID:18034701
PMID:18397576
PMID:22080171
PMID:22280475
PMID:22304812
PMID:22385261
PMID:22447125
PMID:22483350
PMID:22499553
PMID:22540994
PMID:22606986
PMID:22622393
PMID:3946945
PMID:7361809
Patent:CN101481304
Reaxys:1209246
Wikipedia:Formic_acid
FORMIC ACID
Formic acid
formic acid
chebi_ontology
Acide formique
Ameisensaeure
H-COOH
HCO2H
HCOOH
Methanoic acid
aminic acid
bilorin
formylic acid
hydrogen carboxylic acid
methoic acid
CHEBI:30751
formic acid
Beilstein:1209246
Beilstein
CAS:64-18-6
ChemIDplus
CAS:64-18-6
KEGG COMPOUND
CAS:64-18-6
NIST Chemistry WebBook
Gmelin:1008
Gmelin
LIPID_MAPS_instance:LMFA01010040
LIPID MAPS
PMID:12591956
Europe PMC
PMID:14637377
Europe PMC
PMID:15811469
Europe PMC
PMID:16120414
Europe PMC
PMID:16185830
Europe PMC
PMID:16222862
Europe PMC
PMID:16230297
Europe PMC
PMID:16445901
Europe PMC
PMID:16465784
Europe PMC
PMID:18034701
Europe PMC
PMID:18397576
Europe PMC
PMID:22080171
Europe PMC
PMID:22280475
Europe PMC
PMID:22304812
Europe PMC
PMID:22385261
Europe PMC
PMID:22447125
Europe PMC
PMID:22483350
Europe PMC
PMID:22499553
Europe PMC
PMID:22540994
Europe PMC
PMID:22606986
Europe PMC
PMID:22622393
Europe PMC
PMID:3946945
Europe PMC
PMID:7361809
Europe PMC
Reaxys:1209246
Reaxys
FORMIC ACID
PDBeChem
Formic acid
KEGG_COMPOUND
formic acid
IUPAC
Acide formique
ChemIDplus
Ameisensaeure
ChemIDplus
H-COOH
IUPAC
HCO2H
ChEBI
HCOOH
NIST_Chemistry_WebBook
Methanoic acid
KEGG_COMPOUND
aminic acid
ChemIDplus
bilorin
ChemIDplus
formylic acid
ChemIDplus
hydrogen carboxylic acid
ChemIDplus
methoic acid
ChEBI
A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
0
HOR
17.007
17.00274
O[*]
CHEBI:13804
CHEBI:22288
CHEBI:2553
KEGG:C00069
Alcohol
alcohols
chebi_ontology
an alcohol
CHEBI:30879
alcohol
Alcohol
KEGG_COMPOUND
alcohols
IUPAC
an alcohol
UniProt
0
C2H5N
InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
NOWKCMXCCJGMRR-UHFFFAOYSA-N
43.06784
43.04220
C1CN1
CHEBI:24004
CHEBI:2954
Beilstein:102380
CAS:151-56-4
Gmelin:616
KEGG:C11687
Aziridine
aziridine
FlyBase miscellaneous CV
chebi_ontology
EI
azacyclopropane
dimethyleneimine
ethyleneimine
ethylenimine
CHEBI:30969
aziridine
Beilstein:102380
Beilstein
CAS:151-56-4
ChemIDplus
CAS:151-56-4
KEGG COMPOUND
CAS:151-56-4
NIST Chemistry WebBook
Gmelin:616
Gmelin
Aziridine
KEGG_COMPOUND
aziridine
IUPAC
EI
NIST_Chemistry_WebBook
azacyclopropane
NIST_Chemistry_WebBook
dimethyleneimine
NIST_Chemistry_WebBook
ethyleneimine
ChemIDplus
ethylenimine
NIST_Chemistry_WebBook
A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals.
-1
C5H9O2
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)/p-1
NQPDZGIKBAWPEJ-UHFFFAOYSA-M
101.12376
101.06080
CCCCC([O-])=O
CHEBI:14751
CHEBI:25890
Beilstein:3903735
CAS:10023-74-2
Gmelin:325619
PMID:17314444
PMID:18783570
Reaxys:3903735
pentanoate
chebi_ontology
CH3-[CH2]3-COO(-)
n-propylacetate
pentanoate
pentanoic acid, ion(1-)
CHEBI:31011
valerate
Beilstein:3903735
Beilstein
CAS:10023-74-2
ChemIDplus
Gmelin:325619
Gmelin
PMID:17314444
Europe PMC
PMID:18783570
Europe PMC
Reaxys:3903735
Reaxys
pentanoate
IUPAC
CH3-[CH2]3-COO(-)
IUPAC
n-propylacetate
ChEBI
pentanoate
UniProt
pentanoic acid, ion(1-)
ChemIDplus
A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group.
-1
C3H6NO2S
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1
XUJNEKJLAYXESH-UHFFFAOYSA-M
120.15128
120.01247
NC(CS)C([O-])=O
Beilstein:4128885
Gmelin:363235
Reaxys:4128885
cysteinate(1-)
hydrogen cysteinate
chebi_ontology
2-amino-3-mercaptopropanoate
2-amino-3-sulfanylpropanoate
cys(-)
cysteine monoanion
CHEBI:32456
cysteinate(1-)
Beilstein:4128885
Beilstein
Gmelin:363235
Gmelin
Reaxys:4128885
Reaxys
cysteinate(1-)
JCBN
hydrogen cysteinate
IUPAC
2-amino-3-mercaptopropanoate
ChEBI
2-amino-3-sulfanylpropanoate
IUPAC
cys(-)
IUPAC
cysteine monoanion
JCBN
-2
C3H5NO2S
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2
XUJNEKJLAYXESH-UHFFFAOYSA-L
119.14334
119.00520
NC(C[S-])C([O-])=O
Gmelin:49990
cysteinate
cysteinate(2-)
chebi_ontology
2-amino-3-sulfidopropanoate
cysteine dianion
CHEBI:32457
cysteinate(2-)
Gmelin:49990
Gmelin
cysteinate
IUPAC
cysteinate(2-)
JCBN
2-amino-3-sulfidopropanoate
IUPAC
cysteine dianion
JCBN
+1
C3H8NO2S
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1
XUJNEKJLAYXESH-UHFFFAOYSA-O
122.16716
122.02703
[NH3+]C(CS)C(O)=O
Gmelin:325859
1-carboxy-2-sulfanylethanaminium
cysteinium
chebi_ontology
1-carboxy-2-mercaptoethanaminium
H2cys(+)
cysteine cation
CHEBI:32458
cysteinium
Gmelin:325859
Gmelin
1-carboxy-2-sulfanylethanaminium
IUPAC
cysteinium
JCBN
1-carboxy-2-mercaptoethanaminium
ChEBI
H2cys(+)
IUPAC
cysteine cation
JCBN
An optically active form of phenylalaninate having L-configuration.
-1
C9H10NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m0/s1
COLNVLDHVKWLRT-QMMMGPOBSA-M
164.18120
164.07170
N[C@@H](Cc1ccccc1)C([O-])=O
Beilstein:4136718
Gmelin:329084
PMID:21956539
Reaxys:4136718
L-phenylalaninate
chebi_ontology
(2S)-2-amino-3-phenylpropanoate
L-phenylalanine anion
CHEBI:32486
L-phenylalaninate
Beilstein:4136718
Beilstein
Gmelin:329084
Gmelin
PMID:21956539
Europe PMC
Reaxys:4136718
Reaxys
L-phenylalaninate
IUPAC
(2S)-2-amino-3-phenylpropanoate
IUPAC
L-phenylalanine anion
JCBN
An optically active form of phenylalaninium having L-configuration.
+1
C9H12NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m0/s1
COLNVLDHVKWLRT-QMMMGPOBSA-O
166.19710
166.08626
[NH3+][C@@H](Cc1ccccc1)C(O)=O
PMID:21956539
L-phenylalaninium
chebi_ontology
(1S)-1-carboxy-2-phenylethanaminium
L-phenylalanine cation
CHEBI:32487
L-phenylalaninium
PMID:21956539
Europe PMC
L-phenylalaninium
IUPAC
(1S)-1-carboxy-2-phenylethanaminium
IUPAC
L-phenylalanine cation
JCBN
The D-enantiomer of phenylalaninate.
-1
C9H10NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m1/s1
COLNVLDHVKWLRT-MRVPVSSYSA-M
164.18120
164.07170
N[C@H](Cc1ccccc1)C([O-])=O
Beilstein:5740552
Gmelin:746993
D-phenylalaninate
chebi_ontology
(2R)-2-amino-3-phenylpropanoate
D-phenylalanine anion
CHEBI:32494
D-phenylalaninate
Beilstein:5740552
Beilstein
Gmelin:746993
Gmelin
D-phenylalaninate
IUPAC
(2R)-2-amino-3-phenylpropanoate
IUPAC
D-phenylalanine anion
JCBN
An optically active form of phenylalaninium having D-configuration.
+1
C9H12NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m1/s1
COLNVLDHVKWLRT-MRVPVSSYSA-O
166.19710
166.08626
[NH3+][C@H](Cc1ccccc1)C(O)=O
D-phenylalaninium
chebi_ontology
(1R)-1-carboxy-2-phenylethanaminium
D-phenylalanine cation
CHEBI:32495
D-phenylalaninium
D-phenylalaninium
IUPAC
(1R)-1-carboxy-2-phenylethanaminium
IUPAC
D-phenylalanine cation
JCBN
An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group.
-1
C9H10NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1
COLNVLDHVKWLRT-UHFFFAOYSA-M
164.18120
164.07170
NC(Cc1ccccc1)C([O-])=O
Gmelin:329083
phenylalaninate
chebi_ontology
2-amino-3-phenylpropanoate
phenylalanine anion
CHEBI:32504
phenylalaninate
Gmelin:329083
Gmelin
phenylalaninate
IUPAC
2-amino-3-phenylpropanoate
IUPAC
phenylalanine anion
JCBN
An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group.
+1
C9H12NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1
COLNVLDHVKWLRT-UHFFFAOYSA-O
166.19710
166.08626
[NH3+]C(Cc1ccccc1)C(O)=O
phenylalaninium
chebi_ontology
1-carboxy-2-phenylethanaminium
phenylalanine cation
CHEBI:32505
phenylalaninium
phenylalaninium
IUPAC
1-carboxy-2-phenylethanaminium
IUPAC
phenylalanine cation
JCBN
Any cyclic ether in which the oxygen atom forms part of a 3-membered ring.
0
C2OR4
40.02080
39.99491
[*]C1([*])OC1([*])[*]
CHEBI:13828
CHEBI:23930
CHEBI:4812
KEGG:C00722
PMID:10891060
Wikipedia:Epoxide
Epoxide
epoxides
chebi_ontology
Alkene oxide
Olefin oxide
an epoxide
epoxides
CHEBI:32955
epoxide
PMID:10891060
Europe PMC
Epoxide
KEGG_COMPOUND
epoxides
IUPAC
Alkene oxide
KEGG_COMPOUND
Olefin oxide
KEGG_COMPOUND
an epoxide
UniProt
epoxides
ChEBI
An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
CHEBI:22473
CHEBI:2633
KEGG:C00241
Amide
amides
chebi_ontology
CHEBI:32988
amide
Amide
KEGG_COMPOUND
amides
IUPAC
0
BH3O3
InChI=1S/BH3O3/c2-1(3)4/h2-4H
KGBXLFKZBHKPEV-UHFFFAOYSA-N
61.83302
62.01752
[H]OB(O[H])O[H]
CHEBI:22911
CHEBI:31299
CHEBI:41248
BPDB:2136
CAS:10043-35-3
CAS:11113-50-1
Drug_Central:3035
Gmelin:1585
KEGG:C12486
KEGG:D01089
MolBase:1644
PDBeChem:BO3
PPDB:2136
BORIC ACID
Boric acid
boric acid
trihydroxidoboron
FlyBase miscellaneous CV
chebi_ontology
B(OH)3
H3BO3
[B(OH)3]
boron trihydroxide
orthoboric acid
CHEBI:33118
boric acid
CAS:10043-35-3
ChemIDplus
CAS:10043-35-3
KEGG COMPOUND
CAS:10043-35-3
NIST Chemistry WebBook
CAS:11113-50-1
ChemIDplus
Drug_Central:3035
DrugCentral
Gmelin:1585
Gmelin
BORIC ACID
PDBeChem
Boric acid
KEGG_COMPOUND
boric acid
IUPAC
trihydroxidoboron
IUPAC
B(OH)3
NIST_Chemistry_WebBook
H3BO3
IUPAC
[B(OH)3]
MolBase
boron trihydroxide
NIST_Chemistry_WebBook
orthoboric acid
NIST_Chemistry_WebBook
boron oxoacid
chebi_ontology
boron oxoacids
oxoacids of boron
CHEBI:33145
boron oxoacid
boron oxoacid
ChEBI
boron oxoacids
ChEBI
oxoacids of boron
ChEBI
Any micronutrient that is an organic compound. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines.
CHEBI:10004
CHEBI:27305
Wikipedia:Vitamin
Vitamin
chebi_ontology
vitamina
vitaminas
vitamine
vitamines
vitamins
vitaminum
CHEBI:33229
vitamin
Vitamin
ChEBI
vitamina
ChEBI
vitaminas
ChEBI
vitamine
ChEBI
vitamines
ChEBI
vitamins
ChEBI
vitaminum
ChEBI
Intended use of the molecular entity or part thereof by humans.
chebi_ontology
CHEBI:33232
application
A particle not known to have substructure.
elementary particle
chebi_ontology
elementary particles
CHEBI:33233
fundamental particle
elementary particle
IUPAC
elementary particles
ChEBI
A monoatomic entity is a molecular entity consisting of a single atom.
chebi_ontology
atomic entity
monoatomic entities
CHEBI:33238
monoatomic entity
atomic entity
ChEBI
monoatomic entities
ChEBI
An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands).
coordination entities
coordination entity
chebi_ontology
coordination compounds
CHEBI:33240
coordination entity
coordination entities
IUPAC
coordination entity
IUPAC
coordination compounds
ChEBI
chebi_ontology
oxoacid derivatives
CHEBI:33241
oxoacid derivative
oxoacid derivatives
ChEBI
chebi_ontology
inorganic hydrides
CHEBI:33242
inorganic hydride
inorganic hydrides
ChEBI
An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
chebi_ontology
organic fundamental parents
organic parent hydrides
CHEBI:33245
organic fundamental parent
organic fundamental parents
ChEBI
organic parent hydrides
ChEBI
Any substituent group which does not contain carbon.
chebi_ontology
inorganic groups
CHEBI:33246
inorganic group
inorganic groups
ChEBI
Any substituent group or skeleton containing carbon.
chebi_ontology
organic groups
CHEBI:33247
organic group
organic groups
ChEBI
A univalent group formed by removing a hydrogen atom from a hydrocarbon.
hydrocarbyl group
hydrocarbyl groups
chebi_ontology
groupe hydrocarbyle
grupo hidrocarbilo
grupos hidrocarbilo
CHEBI:33248
hydrocarbyl group
hydrocarbyl group
IUPAC
hydrocarbyl groups
IUPAC
groupe hydrocarbyle
IUPAC
grupo hidrocarbilo
IUPAC
grupos hidrocarbilo
IUPAC
Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
organyl group
organyl groups
chebi_ontology
groupe organyle
grupo organilo
grupos organilo
CHEBI:33249
organyl group
organyl group
IUPAC
organyl groups
IUPAC
groupe organyle
IUPAC
grupo organilo
IUPAC
grupos organilo
IUPAC
A chemical entity constituting the smallest component of an element having the chemical properties of the element.
CHEBI:22671
CHEBI:23907
atom
chebi_ontology
atome
atomo
atoms
atomus
element
elements
CHEBI:33250
atom
atom
IUPAC
atome
IUPAC
atomo
IUPAC
atoms
ChEBI
atomus
ChEBI
element
ChEBI
elements
ChEBI
A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
nucleus
chebi_ontology
Atomkern
Kern
noyau
noyau atomique
nuclei
nucleo
nucleo atomico
nucleus atomi
CHEBI:33252
atomic nucleus
nucleus
IUPAC
Atomkern
ChEBI
Kern
ChEBI
noyau
IUPAC
noyau atomique
ChEBI
nuclei
ChEBI
nucleo
IUPAC
nucleo atomico
ChEBI
nucleus atomi
ChEBI
Heavy nuclear particle: proton or neutron.
nucleon
chebi_ontology
Nukleon
Nukleonen
nucleons
CHEBI:33253
nucleon
nucleon
IUPAC
nucleon
IUPAC
Nukleon
ChEBI
Nukleonen
ChEBI
nucleons
ChEBI
A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
primary amide
primary amides
chebi_ontology
CHEBI:33256
primary amide
primary amide
IUPAC
primary amides
IUPAC
A molecular entity all atoms of which have the same atomic number.
chebi_ontology
homoatomic entity
homoatomic molecular entities
homoatomic molecular entity
CHEBI:33259
elemental molecular entity
homoatomic entity
ChEBI
homoatomic molecular entities
ChEBI
homoatomic molecular entity
ChEBI
An organosulfur compound is a compound containing at least one carbon-sulfur bond.
CHEBI:23010
CHEBI:25714
Wikipedia:Organosulfur_compounds
organosulfur compound
chebi_ontology
organosulfur compounds
CHEBI:33261
organosulfur compound
organosulfur compound
ChEBI
organosulfur compounds
ChEBI
An anion consisting of more than one atom.
chebi_ontology
polyatomic anions
CHEBI:33273
polyatomic anion
polyatomic anions
ChEBI
chebi_ontology
chemical messenger
CHEBI:33280
molecular messenger
chemical messenger
ChEBI
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
CHEBI:22582
PMID:12964249
PMID:22117953
PMID:22439833
PMID:22849268
PMID:22849276
PMID:22958833
chebi_ontology
Antibiotika
Antibiotikum
antibiotic
antibiotics
antibiotique
antimicrobial
antimicrobial agents
antimicrobials
microbicide
microbicides
CHEBI:33281
antimicrobial agent
PMID:12964249
Europe PMC
PMID:22117953
Europe PMC
PMID:22439833
Europe PMC
PMID:22849268
Europe PMC
PMID:22849276
Europe PMC
PMID:22958833
Europe PMC
Antibiotika
ChEBI
Antibiotikum
ChEBI
antibiotic
ChEBI
antibiotics
ChEBI
antibiotique
IUPAC
antimicrobial
ChEBI
antimicrobial agents
ChEBI
antimicrobials
ChEBI
microbicide
ChEBI
microbicides
ChEBI
A substance (or active part thereof) that kills or slows the growth of bacteria.
chebi_ontology
antibacterial agents
antibacterials
bactericide
bactericides
CHEBI:33282
antibacterial agent
antibacterial agents
ChEBI
antibacterials
ChEBI
bactericide
ChEBI
bactericides
ChEBI
A nutrient is a food component that an organism uses to survive and grow.
chebi_ontology
nutrients
CHEBI:33284
nutrient
nutrients
ChEBI
A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
chebi_ontology
heteroorganic entities
organoelement compounds
CHEBI:33285
heteroorganic entity
heteroorganic entities
ChEBI
organoelement compounds
ChEBI
An agrochemical is a substance that is used in agriculture or horticulture.
Wikipedia:Agrochemical
chebi_ontology
agrichemical
agrichemicals
agricultural chemicals
agrochemicals
CHEBI:33286
agrochemical
agrichemical
ChEBI
agrichemicals
ChEBI
agricultural chemicals
ChEBI
agrochemicals
ChEBI
A fertilizer is any substance that is added to soil or water to assist the growth of plants.
chebi_ontology
fertiliser
fertilizers
CHEBI:33287
fertilizer
fertiliser
ChEBI
fertilizers
ChEBI
A substance administered to aid diagnosis of a disease.
chebi_ontology
diagnostic aid
CHEBI:33295
diagnostic agent
diagnostic aid
ChEBI
A molecular entity containing one or more atoms of an alkali metal.
chebi_ontology
alkali metal molecular entities
CHEBI:33296
alkali metal molecular entity
alkali metal molecular entities
ChEBI
Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
pnictogens
chebi_ontology
group 15 elements
group V elements
nitrogenoideos
nitrogenoides
pnictogene
pnictogenes
CHEBI:33300
pnictogen
pnictogens
IUPAC
group 15 elements
ChEBI
group V elements
ChEBI
nitrogenoideos
ChEBI
nitrogenoides
ChEBI
pnictogene
ChEBI
pnictogenes
ChEBI
A p-block molecular entity containing any pnictogen.
pnictogen molecular entity
chebi_ontology
pnictogen molecular entities
CHEBI:33302
pnictogen molecular entity
pnictogen molecular entity
ChEBI
pnictogen molecular entities
ChEBI
Any p-block element belonging to the group 16 family of the periodic table.
PMID:17084588
chalcogen
chalcogens
chebi_ontology
Chalkogen
Chalkogene
anfigeno
anfigenos
calcogeno
calcogenos
chalcogene
chalcogenes
group 16 elements
group VI elements
CHEBI:33303
chalcogen
PMID:17084588
Europe PMC
chalcogen
IUPAC
chalcogens
IUPAC
Chalkogen
ChEBI
Chalkogene
ChEBI
anfigeno
ChEBI
anfigenos
ChEBI
calcogeno
ChEBI
calcogenos
ChEBI
chalcogene
ChEBI
chalcogenes
ChEBI
group 16 elements
ChEBI
group VI elements
ChEBI
Any p-block molecular entity containing a chalcogen.
chalcogen molecular entity
chebi_ontology
chalcogen compounds
chalcogen molecular entities
CHEBI:33304
chalcogen molecular entity
chalcogen molecular entity
ChEBI
chalcogen compounds
ChEBI
chalcogen molecular entities
ChEBI
group 14 elements
chebi_ontology
carbon group element
carbon group elements
carbonoides
cristallogene
cristallogenes
group IV elements
CHEBI:33306
carbon group element atom
group 14 elements
IUPAC
carbon group element
ChEBI
carbon group elements
ChEBI
carbonoides
ChEBI
cristallogene
ChEBI
cristallogenes
ChEBI
group IV elements
ChEBI
An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.
0
CO2R2
44.010
43.98983
[*]C(=O)O[*]
CHEBI:13204
CHEBI:23028
CHEBI:3408
KEGG:C02391
Wikipedia:Ester
Carboxylic ester
carboxylic esters
chebi_ontology
a carboxylic ester
carboxylic acid esters
CHEBI:33308
carboxylic ester
Carboxylic ester
KEGG_COMPOUND
carboxylic esters
IUPAC
a carboxylic ester
UniProt
carboxylic acid esters
ChEBI
group 13 elements
chebi_ontology
Element der Borgruppe
boron group element
boron group elements
group III elements
CHEBI:33317
boron group element atom
group 13 elements
IUPAC
Element der Borgruppe
ChEBI
boron group element
ChEBI
boron group elements
ChEBI
group III elements
ChEBI
An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
main group elements
chebi_ontology
Hauptgruppenelement
Hauptgruppenelemente
main group element
CHEBI:33318
main group element atom
main group elements
IUPAC
Hauptgruppenelement
ChEBI
Hauptgruppenelemente
ChEBI
main group element
ChEBI
A group derived from an arene by removal of a hydrogen atom from a ring carbon atom.
aryl groups
chebi_ontology
Arylgruppe
groupe aryle
grupos arilo
CHEBI:33338
aryl group
aryl groups
IUPAC
Arylgruppe
ChEBI
groupe aryle
IUPAC
grupos arilo
IUPAC
group 10 elements
chebi_ontology
nickel group element
nickel group elements
CHEBI:33362
nickel group element atom
group 10 elements
IUPAC
nickel group element
ChEBI
nickel group elements
ChEBI
0
Pt
InChI=1S/Pt
BASFCYQUMIYNBI-UHFFFAOYSA-N
195.078
194.96479
[Pt]
CAS:7440-06-4
WebElements:Pt
platinum
chebi_ontology
78Pt
Platin
Pt
platine
platino
CHEBI:33364
platinum
CAS:7440-06-4
ChemIDplus
CAS:7440-06-4
NIST Chemistry WebBook
platinum
IUPAC
78Pt
IUPAC
Platin
ChEBI
Pt
IUPAC
platine
ChEBI
platino
ChEBI
chebi_ontology
PGM
Platinmetalle
Platinoide
platinoid
platinum group metal
platinum group metals
platinum metals
CHEBI:33365
platinum group metal atom
PGM
ChEBI
Platinmetalle
ChEBI
Platinoide
ChEBI
platinoid
ChEBI
platinum group metal
ChEBI
platinum group metals
ChEBI
platinum metals
ChEBI
group 11 elements
chebi_ontology
coinage metals
copper group element
copper group elements
CHEBI:33366
copper group element atom
group 11 elements
IUPAC
coinage metals
ChEBI
copper group element
ChEBI
copper group elements
ChEBI
chebi_ontology
oxoacids of sulfur
sulfur oxoacids
CHEBI:33402
sulfur oxoacid
oxoacids of sulfur
ChEBI
sulfur oxoacids
ChEBI
A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
hydracid
chebi_ontology
hydracids
CHEBI:33405
hydracid
hydracid
IUPAC
hydracids
ChEBI
chebi_ontology
pnictogen oxoacids
CHEBI:33408
pnictogen oxoacid
pnictogen oxoacids
ChEBI
sulfur oxoacid derivative
chebi_ontology
sulfur oxoacid derivatives
CHEBI:33424
sulfur oxoacid derivative
sulfur oxoacid derivative
ChEBI
sulfur oxoacid derivatives
ChEBI
-1
0.00000
[*-]
chebi_ontology
monoatomic monoanions
CHEBI:33429
monoatomic monoanion
monoatomic monoanions
ChEBI
chebi_ontology
CHEBI:33431
elemental chlorine
0
Cl
35.453
34.96885
chebi_ontology
atomic chlorine
CHEBI:33432
monoatomic chlorine
atomic chlorine
ChEBI
chebi_ontology
monoatomic halogens
CHEBI:33433
monoatomic halogen
monoatomic halogens
ChEBI
elemental halogen
chebi_ontology
elemental halogens
CHEBI:33434
elemental halogen
elemental halogen
ChEBI
elemental halogens
ChEBI
Arylmethyl groups and derivatives formed by substitution: ArCR2-.
benzylic group
benzylic groups
chebi_ontology
benzylic groups
groupe benzylique
CHEBI:33452
benzylic group
benzylic group
IUPAC
benzylic groups
IUPAC
benzylic groups
ChEBI
groupe benzylique
IUPAC
A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.
phosphorus oxoacid
chebi_ontology
Oxosaeure des Phosphors
oxoacids of phosphorus
phosphorus oxoacids
CHEBI:33457
phosphorus oxoacid
phosphorus oxoacid
ChEBI
Oxosaeure des Phosphors
ChEBI
oxoacids of phosphorus
ChEBI
phosphorus oxoacids
ChEBI
pnictogen oxoanion
chebi_ontology
pnictogen oxoanions
CHEBI:33459
pnictogen oxoanion
pnictogen oxoanion
ChEBI
pnictogen oxoanions
ChEBI
phosphorus oxoanion
chebi_ontology
oxoanions of phosphorus
phosphorus oxoanions
CHEBI:33461
phosphorus oxoanion
phosphorus oxoanion
ChEBI
oxoanions of phosphorus
ChEBI
phosphorus oxoanions
ChEBI
sulfur oxoanion
chebi_ontology
oxoanions of sulfur
sulfur oxoanions
CHEBI:33482
sulfur oxoanion
sulfur oxoanion
ChEBI
oxoanions of sulfur
ChEBI
sulfur oxoanions
ChEBI
chalcogen oxoacid
chebi_ontology
chalcogen oxoacids
CHEBI:33484
chalcogen oxoacid
chalcogen oxoacid
ChEBI
chalcogen oxoacids
ChEBI
chalcogen oxoanion
chebi_ontology
chalcogen oxoanions
CHEBI:33485
chalcogen oxoanion
chalcogen oxoanion
ChEBI
chalcogen oxoanions
ChEBI
A molecular entity containing one or more atoms of a transition element.
chebi_ontology
transition element molecular entities
transition metal molecular entity
CHEBI:33497
transition element molecular entity
transition element molecular entities
ChEBI
transition metal molecular entity
ChEBI
chebi_ontology
alkali metal cations
CHEBI:33504
alkali metal cation
alkali metal cations
ChEBI
chebi_ontology
transition element cations
transition metal cation
CHEBI:33515
transition element cation
transition element cations
ChEBI
transition metal cation
ChEBI
An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
CHEBI:25217
CHEBI:6788
KEGG:C00050
PMID:21784043
Wikipedia:Metal
chebi_ontology
elemental metal
elemental metals
metal element
metal elements
metals
CHEBI:33521
metal atom
PMID:21784043
Europe PMC
elemental metal
ChEBI
elemental metals
ChEBI
metal element
ChEBI
metal elements
ChEBI
metals
ChEBI
The sulfur oxoanion formed by deprotonation of sulfonic acid.
-1
HO3S
InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1
BDHFUVZGWQCTTF-UHFFFAOYSA-M
81.07214
80.96519
[H]S([O-])(=O)=O
Gmelin:971569
hydridotrioxidosulfate(1-)
chebi_ontology
SHO3(-)
[SHO3](-)
sulfonates
CHEBI:33543
sulfonate
Gmelin:971569
Gmelin
hydridotrioxidosulfate(1-)
IUPAC
SHO3(-)
IUPAC
[SHO3](-)
IUPAC
sulfonates
ChEBI
An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon.
0
HO3SR
81.07100
80.96464
OS([*])(=O)=O
chebi_ontology
organosulfonic acids
sulfonic acids
CHEBI:33551
organosulfonic acid
organosulfonic acids
ChEBI
sulfonic acids
ChEBI
sulfonic acid derivative
chebi_ontology
derivatives of sulfonic acid
sulfonic acid derivatives
CHEBI:33552
sulfonic acid derivative
sulfonic acid derivative
ChEBI
derivatives of sulfonic acid
ChEBI
sulfonic acid derivatives
ChEBI
An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.
-1
O3SR
80.064
79.95681
*S([O-])(=O)=O
chebi_ontology
organosulfonate
organosulfonate oxoanions
organosulfonates
CHEBI:33554
organosulfonate oxoanion
organosulfonate
ChEBI
organosulfonate oxoanions
ChEBI
organosulfonates
ChEBI
Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group.
chebi_ontology
arenesulfonic acids
arylsulfonic acid
arylsulfonic acids
CHEBI:33555
arenesulfonic acid
arenesulfonic acids
ChEBI
arylsulfonic acid
ChEBI
arylsulfonic acids
ChEBI
An amino-acid anion obtained by deprotonation of any alpha-amino acid.
alpha-amino-acid anion
chebi_ontology
alpha-amino acid anions
alpha-amino-acid anions
CHEBI:33558
alpha-amino-acid anion
alpha-amino-acid anion
ChEBI
alpha-amino acid anions
ChEBI
alpha-amino-acid anions
ChEBI
chebi_ontology
s-block element
s-block elements
CHEBI:33559
s-block element atom
s-block element
ChEBI
s-block elements
ChEBI
Any main group element atom belonging to the p-block of the periodic table.
chebi_ontology
p-block element
p-block elements
CHEBI:33560
p-block element atom
p-block element
ChEBI
p-block elements
ChEBI
chebi_ontology
d-block element
d-block elements
CHEBI:33561
d-block element atom
d-block element
ChEBI
d-block elements
ChEBI
CHEBI:22705
CHEBI:22711
chebi_ontology
CHEBI:33570
benzenediols
A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
0
CHO2R
45.01740
44.99765
OC([*])=O
CHEBI:13428
CHEBI:13627
CHEBI:23027
PMID:17147560
PMID:18433345
Wikipedia:Carboxylic_acid
carboxylic acid
carboxylic acids
chebi_ontology
Carbonsaeure
Carbonsaeuren
Karbonsaeure
RC(=O)OH
acide carboxylique
acides carboxyliques
acido carboxilico
acidos carboxilicos
CHEBI:33575
carboxylic acid
PMID:17147560
Europe PMC
PMID:18433345
Europe PMC
carboxylic acid
IUPAC
carboxylic acids
IUPAC
Carbonsaeure
ChEBI
Carbonsaeuren
ChEBI
Karbonsaeure
ChEBI
RC(=O)OH
IUPAC
acide carboxylique
IUPAC
acides carboxyliques
IUPAC
acido carboxilico
IUPAC
acidos carboxilicos
IUPAC
Any carboxylic acid having a sulfur substituent.
chebi_ontology
S-containing carboxylic acid
S-containing carboxylic acids
sulfur-containing carboxylic acids
CHEBI:33576
sulfur-containing carboxylic acid
S-containing carboxylic acid
ChEBI
S-containing carboxylic acids
ChEBI
sulfur-containing carboxylic acids
ChEBI
A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
chebi_ontology
main group compounds
main group molecular entities
CHEBI:33579
main group molecular entity
main group compounds
ChEBI
main group molecular entities
ChEBI
chebi_ontology
boron group molecular entities
CHEBI:33581
boron group molecular entity
boron group molecular entities
ChEBI
carbon group molecular entity
chebi_ontology
carbon group molecular entities
CHEBI:33582
carbon group molecular entity
carbon group molecular entity
ChEBI
carbon group molecular entities
ChEBI
Any molecule that consists of a series of atoms joined together to form a ring.
Wikipedia:Cyclic_compound
chebi_ontology
cyclic compounds
CHEBI:33595
cyclic compound
cyclic compounds
ChEBI
A cyclic compound having as ring members atoms of the same element only.
homocyclic compound
homocyclic compounds
chebi_ontology
isocyclic compounds
CHEBI:33597
homocyclic compound
homocyclic compound
IUPAC
homocyclic compounds
IUPAC
isocyclic compounds
IUPAC
A homocyclic compound in which all of the ring members are carbon atoms.
carbocyclic compound
carbocyclic compounds
chebi_ontology
carbocycle
CHEBI:33598
carbocyclic compound
carbocyclic compound
IUPAC
carbocyclic compounds
IUPAC
carbocycle
ChEBI
chebi_ontology
hydrogen compounds
hydrogen molecular entities
CHEBI:33608
hydrogen molecular entity
hydrogen compounds
ChEBI
hydrogen molecular entities
ChEBI
boron oxoanion
chebi_ontology
boron oxoanions
CHEBI:33619
boron oxoanion
boron oxoanion
ChEBI
boron oxoanions
ChEBI
chebi_ontology
polycyclic compounds
CHEBI:33635
polycyclic compound
polycyclic compounds
ChEBI
A molecule that features two fused rings.
chebi_ontology
bicyclic compounds
CHEBI:33636
bicyclic compound
bicyclic compounds
ChEBI
A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms.
ortho-fused polycyclic compounds
chebi_ontology
ortho-fused compounds
CHEBI:33637
ortho-fused compound
ortho-fused polycyclic compounds
IUPAC
ortho-fused compounds
ChEBI
A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have n common faces and less than 2n common atoms.
ortho- and peri-fused polycyclic compounds
chebi_ontology
ortho- and peri-fused compounds
CHEBI:33639
ortho- and peri-fused compound
ortho- and peri-fused polycyclic compounds
IUPAC
ortho- and peri-fused compounds
ChEBI
Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.
aliphatic compounds
chebi_ontology
CHEBI:33653
aliphatic compound
aliphatic compounds
IUPAC
A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
aromatic compounds
aromatic molecular entity
chebi_ontology
aromatics
aromatische Verbindungen
CHEBI:33655
aromatic compound
aromatic compounds
IUPAC
aromatic molecular entity
IUPAC
aromatics
ChEBI
aromatische Verbindungen
ChEBI
Any monocyclic or polycyclic aromatic hydrocarbon.
arene
arenes
chebi_ontology
aromatic hydrocarbons
CHEBI:33658
arene
arene
IUPAC
arenes
IUPAC
aromatic hydrocarbons
IUPAC
chebi_ontology
organic aromatic compounds
CHEBI:33659
organic aromatic compound
organic aromatic compounds
ChEBI
chebi_ontology
monocyclic compounds
CHEBI:33661
monocyclic compound
monocyclic compounds
ChEBI
A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms.
annulene
annulenes
chebi_ontology
CHEBI:33662
annulene
annulene
IUPAC
annulenes
IUPAC
cyclic hydrocarbon
chebi_ontology
cyclic hydrocarbons
CHEBI:33663
cyclic hydrocarbon
cyclic hydrocarbon
ChEBI
cyclic hydrocarbons
ChEBI
monocyclic hydrocarbon
monocyclic hydrocarbons
chebi_ontology
monocyclic hydrocarbons
CHEBI:33664
monocyclic hydrocarbon
monocyclic hydrocarbon
ChEBI
monocyclic hydrocarbons
IUPAC
monocyclic hydrocarbons
ChEBI
polycyclic hydrocarbon
polycyclic hydrocarbons
chebi_ontology
CHEBI:33666
polycyclic hydrocarbon
polycyclic hydrocarbon
IUPAC
polycyclic hydrocarbons
IUPAC
heteromonocyclic compound
heteromonocyclic compounds
chebi_ontology
CHEBI:33670
heteromonocyclic compound
heteromonocyclic compound
IUPAC
heteromonocyclic compounds
IUPAC
A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.
heteropolycyclic compounds
chebi_ontology
polyheterocyclic compounds
CHEBI:33671
heteropolycyclic compound
heteropolycyclic compounds
IUPAC
polyheterocyclic compounds
ChEBI
A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.
heterobicyclic compounds
chebi_ontology
CHEBI:33672
heterobicyclic compound
heterobicyclic compounds
IUPAC
An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
s-block molecular entity
chebi_ontology
s-block compounds
s-block molecular entities
CHEBI:33674
s-block molecular entity
s-block molecular entity
ChEBI
s-block compounds
ChEBI
s-block molecular entities
ChEBI
A main group molecular entity that contains one or more atoms of a p-block element.
chebi_ontology
p-block compounds
p-block molecular entities
p-block molecular entitiy
CHEBI:33675
p-block molecular entity
p-block compounds
ChEBI
p-block molecular entities
ChEBI
p-block molecular entitiy
ChEBI
A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.
d-block molecular entity
chebi_ontology
d-block compounds
d-block molecular entities
CHEBI:33676
d-block molecular entity
d-block molecular entity
ChEBI
d-block compounds
ChEBI
d-block molecular entities
ChEBI
Hydrides are chemical compounds of hydrogen with other chemical elements.
chebi_ontology
CHEBI:33692
hydrides
A macromolecule formed by a living organism.
biopolymer
chebi_ontology
Biopolymere
biomacromolecules
biopolymers
CHEBI:33694
biomacromolecule
biopolymer
IUPAC
Biopolymere
ChEBI
biomacromolecules
ChEBI
biopolymers
ChEBI
chebi_ontology
genetically encoded biomacromolecules
genetically encoded biopolymers
information biomacromolecules
information biopolymers
information macromolecule
information macromolecules
CHEBI:33695
information biomacromolecule
genetically encoded biomacromolecules
ChEBI
genetically encoded biopolymers
ChEBI
information biomacromolecules
ChEBI
information biopolymers
ChEBI
information macromolecule
ChEBI
information macromolecules
ChEBI
A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
nucleic acids
chebi_ontology
NA
Nukleinsaeure
Nukleinsaeuren
acide nucleique
acides nucleiques
acido nucleico
acidos nucleicos
CHEBI:33696
nucleic acid
nucleic acids
IUPAC
NA
ChEBI
Nukleinsaeure
ChEBI
Nukleinsaeuren
ChEBI
acide nucleique
ChEBI
acides nucleiques
ChEBI
acido nucleico
ChEBI
acidos nucleicos
ChEBI
A cation consisting of more than one atom.
chebi_ontology
polyatomic cations
CHEBI:33702
polyatomic cation
polyatomic cations
ChEBI
amino-acid cation
chebi_ontology
amino acid cation
amino-acid cations
CHEBI:33703
amino-acid cation
amino-acid cation
ChEBI
amino acid cation
ChEBI
amino-acid cations
ChEBI
An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group.
0
C2H4NO2R
74.05870
74.02420
NC([*])C(O)=O
CHEBI:10208
CHEBI:13779
CHEBI:22442
CHEBI:2642
KEGG:C00045
KEGG:C05167
alpha-amino acid
chebi_ontology
Amino acid
Amino acids
alpha-amino acids
alpha-amino carboxylic acids
CHEBI:33704
alpha-amino acid
alpha-amino acid
IUPAC
Amino acid
KEGG_COMPOUND
Amino acids
KEGG_COMPOUND
alpha-amino acids
ChEBI
alpha-amino acids
JCBN
alpha-amino carboxylic acids
IUPAC
When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.
amino-acid residue
chebi_ontology
amino acid residue
amino-acid residues
CHEBI:33708
amino-acid residue
amino-acid residue
IUPAC
amino acid residue
ChEBI
amino-acid residues
JCBN
A carboxylic acid containing one or more amino groups.
CHEBI:13815
CHEBI:22477
Wikipedia:Amino_acid
chebi_ontology
Aminocarbonsaeure
Aminokarbonsaeure
Aminosaeure
amino acids
CHEBI:33709
amino acid
Aminocarbonsaeure
ChEBI
Aminokarbonsaeure
ChEBI
Aminosaeure
ChEBI
amino acids
ChEBI
alpha-amino-acid cation
chebi_ontology
alpha-amino acid cations
alpha-amino-acid cations
CHEBI:33719
alpha-amino-acid cation
alpha-amino-acid cation
ChEBI
alpha-amino acid cations
ChEBI
alpha-amino-acid cations
ChEBI
copper group molecular entity
chebi_ontology
copper group molecular entities
CHEBI:33745
copper group molecular entity
copper group molecular entity
ChEBI
copper group molecular entities
ChEBI
nickel group molecular entity
chebi_ontology
nickel group molecular entities
CHEBI:33747
nickel group molecular entity
nickel group molecular entity
ChEBI
nickel group molecular entities
ChEBI
platinum molecular entity
chebi_ontology
platinum compounds
platinum molecular entities
CHEBI:33749
platinum molecular entity
platinum molecular entity
ChEBI
platinum compounds
ChEBI
platinum molecular entities
ChEBI
chebi_ontology
canonical nucleoside residues
common nucleoside residues
nucleoside residue
standard nucleoside residues
CHEBI:33791
canonical nucleoside residue
canonical nucleoside residues
ChEBI
common nucleoside residues
CBN
nucleoside residue
CBN
standard nucleoside residues
ChEBI
chebi_ontology
canonical deoxyribonucleoside residues
common 2'-deoxyribonucleoside residue
common 2'-deoxyribonucleoside residues
dN
dNuc
standard deoxyribonucleoside residues
CHEBI:33793
canonical deoxyribonucleoside residue
canonical deoxyribonucleoside residues
ChEBI
common 2'-deoxyribonucleoside residue
CBN
common 2'-deoxyribonucleoside residues
CBN
dN
CBN
dNuc
CBN
standard deoxyribonucleoside residues
ChEBI
An organic compound having at least one hydroxy group attached to a carbon atom.
CHEBI:64710
hydroxy compounds
chebi_ontology
organic alcohol
organic hydroxy compounds
CHEBI:33822
organic hydroxy compound
hydroxy compounds
IUPAC
organic alcohol
ChEBI
organic hydroxy compounds
ChEBI
Any organic molecule that consists of atoms connected in the form of a ring.
chebi_ontology
organic cyclic compounds
CHEBI:33832
organic cyclic compound
organic cyclic compounds
ChEBI
A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
heteroarenes
chebi_ontology
hetarenes
CHEBI:33833
heteroarene
heteroarenes
IUPAC
hetarenes
IUPAC
chebi_ontology
benzenoid aromatic compounds
benzenoid compound
CHEBI:33836
benzenoid aromatic compound
benzenoid aromatic compounds
ChEBI
benzenoid compound
ChEBI
An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents.
0
C5H8O3R2
116.115
116.04734
[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO
CHEBI:13661
CHEBI:25611
CHEBI:7647
KEGG:C00801
Nucleoside
nucleosides
chebi_ontology
a nucleoside
nucleosides
CHEBI:33838
nucleoside
Nucleoside
KEGG_COMPOUND
nucleosides
IUPAC
a nucleoside
UniProt
nucleosides
ChEBI
A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
Wikipedia:Macromolecule
macromolecule
chebi_ontology
macromolecules
polymer
polymer molecule
polymers
CHEBI:33839
macromolecule
macromolecule
IUPAC
macromolecules
ChEBI
polymer
ChEBI
polymer molecule
IUPAC
polymers
ChEBI
chebi_ontology
aromatic annulenes
CHEBI:33842
aromatic annulene
aromatic annulenes
ChEBI
A monocyclic aromatic hydrocarbon.
chebi_ontology
monocyclic arenes
CHEBI:33847
monocyclic arene
monocyclic arenes
ChEBI
A polycyclic aromatic hydrocarbon.
PMID:15198916
PMID:25679824
Wikipedia:Polycyclic_aromatic_hydrocarbon
chebi_ontology
PAH
PAHs
polycyclic arenes
polycyclic aromatic hydrocarbons
CHEBI:33848
polycyclic arene
PMID:15198916
Europe PMC
PMID:25679824
Europe PMC
PAH
ChEBI
PAHs
ChEBI
polycyclic arenes
ChEBI
polycyclic aromatic hydrocarbons
ChEBI
Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
0
C6HOR5
89.072
89.00274
C1(=C(C(=C(C(=C1*)*)*)*)*)O
CHEBI:13664
CHEBI:13825
CHEBI:25969
CHEBI:2857
KEGG:C15584
MetaCyc:Phenols
Wikipedia:Phenols
phenols
chebi_ontology
Aryl alcohol
a phenol
arenols
CHEBI:33853
phenols
phenols
IUPAC
Aryl alcohol
KEGG_COMPOUND
a phenol
UniProt
arenols
IUPAC
An amino acid whose structure includes an aromatic ring.
0
C2H4NO2R
88.085
74.02420
CHEBI:13820
CHEBI:22623
CHEBI:2835
KEGG:C01021
Wikipedia:Aromatic_amino_acid
Aromatic amino acid
chebi_ontology
aromatic amino acids
CHEBI:33856
aromatic amino acid
Aromatic amino acid
KEGG_COMPOUND
aromatic amino acids
ChEBI
An amino compound in which the amino group is linked directly to an aromatic system.
CHEBI:13827
CHEBI:22622
CHEBI:22646
CHEBI:2834
CHEBI:2863
chebi_ontology
aromatic amines
aryl amine
aryl amines
arylamine
arylamines
CHEBI:33860
aromatic amine
aromatic amines
ChEBI
aryl amine
ChEBI
aryl amines
ChEBI
arylamine
ChEBI
arylamines
ChEBI
chebi_ontology
transition element coordination entities
transition metal coordination compounds
transition metal coordination entities
CHEBI:33861
transition element coordination entity
transition element coordination entities
ChEBI
transition metal coordination compounds
ChEBI
transition metal coordination entities
ChEBI
platinum coordination entity
chebi_ontology
platinum coordination compounds
platinum coordination entities
CHEBI:33862
platinum coordination entity
platinum coordination entity
ChEBI
platinum coordination compounds
ChEBI
platinum coordination entities
ChEBI
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
reagent
chebi_ontology
reactif
reactivo
reagents
CHEBI:33893
reagent
reagent
IUPAC
reactif
IUPAC
reactivo
IUPAC
reagents
ChEBI
chebi_ontology
CHEBI:33937
macronutrient
chebi_ontology
halide salts
halides
CHEBI:33958
halide salt
halide salts
ChEBI
halides
ChEBI
0
C4H10O4S
InChI=1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3
DENRZWYUOJLTMF-UHFFFAOYSA-N
154.186
154.02998
CCOS(=O)(=O)OCC
CAS:64-67-5
KEGG:C14706
Diethyl sulfate
FlyBase miscellaneous CV
chebi_ontology
DES
CHEBI:34699
diethyl sulfate
CAS:64-67-5
KEGG COMPOUND
Diethyl sulfate
KEGG_COMPOUND
DES
KEGG_COMPOUND
A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
0
C4H10N2O
InChI=1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
WBNQDOYYEUMPFS-UHFFFAOYSA-N
102.135
102.07931
CCN(CC)N=O
Beilstein:1744991
CAS:55-18-5
KEGG:C14422
PMID:24696076
PMID:24755254
Reaxys:1744991
N-Nitrosodiethylamine
N-ethyl-N-nitrosoethanamine
FlyBase miscellaneous CV
chebi_ontology
1,1-diethyl-2-oxohydrazine
DANA
DEN
Diethylnitrosamine
N,N-diethylnitrosamine
N,N-diethylnitrosoamine
NDEA
diethylnitrosoamine
CHEBI:34873
N-nitrosodiethylamine
Beilstein:1744991
Beilstein
CAS:55-18-5
ChemIDplus
CAS:55-18-5
KEGG COMPOUND
CAS:55-18-5
NIST Chemistry WebBook
PMID:24696076
Europe PMC
PMID:24755254
Europe PMC
Reaxys:1744991
Reaxys
N-Nitrosodiethylamine
KEGG_COMPOUND
N-ethyl-N-nitrosoethanamine
IUPAC
1,1-diethyl-2-oxohydrazine
NIST_Chemistry_WebBook
DANA
NIST_Chemistry_WebBook
DEN
NIST_Chemistry_WebBook
Diethylnitrosamine
KEGG_COMPOUND
N,N-diethylnitrosamine
ChemIDplus
N,N-diethylnitrosoamine
ChemIDplus
NDEA
KEGG_COMPOUND
diethylnitrosoamine
ChemIDplus
chebi_ontology
nitrogen hydrides
CHEBI:35106
nitrogen hydride
nitrogen hydrides
ChEBI
Saturated acyclic nitrogen hydrides having the general formula NnHn+2.
chebi_ontology
azanes
CHEBI:35107
azane
azanes
ChEBI
chebi_ontology
sulfate salts
sulfates
sulphate salts
sulphates
CHEBI:35175
sulfate salt
sulfate salts
ChEBI
sulfates
ChEBI
sulphate salts
ChEBI
sulphates
ChEBI
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
Wikipedia:Antimetabolite
antimetabolite
chebi_ontology
antimetabolites
CHEBI:35221
antimetabolite
antimetabolite
IUPAC
antimetabolites
ChEBI
A substance that diminishes the rate of a chemical reaction.
inhibitor
chebi_ontology
inhibidor
inhibiteur
inhibitors
CHEBI:35222
inhibitor
inhibitor
IUPAC
inhibidor
ChEBI
inhibiteur
ChEBI
inhibitors
ChEBI
A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
catalyst
chebi_ontology
Katalysator
catalizador
catalyseur
CHEBI:35223
catalyst
catalyst
IUPAC
Katalysator
ChEBI
catalizador
ChEBI
catalyseur
ChEBI
0
C3H7NO2S
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)
XUJNEKJLAYXESH-UHFFFAOYSA-N
121.15922
121.01975
[NH3+]C(CS)C([O-])=O
Gmelin:49992
2-ammonio-3-sulfanylpropanoate
cysteine zwitterion
chebi_ontology
(+)H3N-CH(CH2SH)-COO(-)
2-ammonio-3-mercaptopropanoate
CHEBI:35237
cysteine zwitterion
Gmelin:49992
Gmelin
2-ammonio-3-sulfanylpropanoate
IUPAC
cysteine zwitterion
IUPAC
(+)H3N-CH(CH2SH)-COO(-)
ChEBI
2-ammonio-3-mercaptopropanoate
ChEBI
The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group.
amino acid zwitterion
chebi_ontology
CHEBI:35238
amino acid zwitterion
amino acid zwitterion
ChEBI
Ammonium, NH4(+), and derivatives formed by substitution by univalent groups.
chebi_ontology
ammonium ions
azanium ions
CHEBI:35274
ammonium ion
ammonium ions
ChEBI
azanium ions
ChEBI
Cations of structure R2C=N(+)R2.
iminium ion
chebi_ontology
iminium cations
iminium ions
CHEBI:35286
iminium ion
iminium ion
ChEBI
iminium cations
ChEBI
iminium ions
ChEBI
chebi_ontology
fused compounds
fused polycyclic compounds
fused-ring polycyclic compound
fused-ring polycyclic compounds
polycyclic fused-ring compounds
CHEBI:35293
fused compound
fused compounds
ChEBI
fused polycyclic compounds
ChEBI
fused-ring polycyclic compound
ChEBI
fused-ring polycyclic compounds
ChEBI
polycyclic fused-ring compounds
ChEBI
A polyclic compound in which all of the ring members are carbon atoms.
chebi_ontology
carbopolycyclic compounds
CHEBI:35294
carbopolycyclic compound
carbopolycyclic compounds
ChEBI
chebi_ontology
homopolycyclic compounds
CHEBI:35295
homopolycyclic compound
homopolycyclic compounds
ChEBI
chebi_ontology
ortho-fused polycyclic arenes
CHEBI:35296
ortho-fused polycyclic arene
ortho-fused polycyclic arenes
ChEBI
0
C22H14
InChI=1S/C22H14/c1-3-7-19-15(5-1)9-11-17-14-22-18(13-21(17)19)12-10-16-6-2-4-8-20(16)22/h1-14H
LHRCREOYAASXPZ-UHFFFAOYSA-N
278.34656
278.10955
c1ccc2c(c1)ccc1cc3c(ccc4ccccc34)cc21
CHEBI:18901
CHEBI:34684
CAS:53-70-3
KEGG:C14325
Dibenz[a,h]anthracene
FlyBase miscellaneous CV
chebi_ontology
1,2:5,6-Dibenzanthracene
DBA
CHEBI:35299
dibenz[a,h]anthracene
CAS:53-70-3
ChemIDplus
CAS:53-70-3
KEGG COMPOUND
CAS:53-70-3
NIST Chemistry WebBook
Dibenz[a,h]anthracene
KEGG_COMPOUND
1,2:5,6-Dibenzanthracene
KEGG_COMPOUND
DBA
ChemIDplus
chebi_ontology
ortho- and peri-fused polycyclic arenes
CHEBI:35300
ortho- and peri-fused polycyclic arene
ortho- and peri-fused polycyclic arenes
ChEBI
Any drug that enhances the activity of the central nervous system.
Wikipedia:Central_nervous_system_stimulants
central nervous system stimulant
chebi_ontology
CNS stimulant
analeptic
analeptic agent
analeptic drug
analeptics
central stimulant
CHEBI:35337
central nervous system stimulant
central nervous system stimulant
ChEBI
CNS stimulant
ChEBI
analeptic
ChEBI
analeptic agent
ChEBI
analeptic drug
ChEBI
analeptics
ChEBI
central stimulant
ChEBI
Any heteroorganic entity containing at least one carbon-nitrogen bond.
organonitrogen compounds
chebi_ontology
organonitrogens
CHEBI:35352
organonitrogen compound
organonitrogen compounds
IUPAC
organonitrogens
ChEBI
Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom.
KEGG:C06060
carboxamidines
chebi_ontology
Amidines
carboxamidines
CHEBI:35359
carboxamidine
carboxamidines
IUPAC
Amidines
KEGG_COMPOUND
carboxamidines
ChEBI
Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
0
CHO2R
45.01740
44.99765
OC([*])=O
CHEBI:13633
CHEBI:24024
CHEBI:4984
KEGG:C00162
PMID:14287444
PMID:14300208
PMID:14328676
Wikipedia:Fatty_acid
Fatty acid
fatty acids
chebi_ontology
Fettsaeure
Fettsaeuren
acide gras
acides gras
acido graso
acidos grasos
fatty acids
CHEBI:35366
fatty acid
PMID:14287444
Europe PMC
PMID:14300208
Europe PMC
PMID:14328676
Europe PMC
Fatty acid
KEGG_COMPOUND
fatty acids
IUPAC
Fettsaeure
ChEBI
Fettsaeuren
ChEBI
acide gras
ChEBI
acides gras
ChemIDplus
acido graso
ChEBI
acidos grasos
ChEBI
fatty acids
ChEBI
An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
CHEBI:33274
CHEBI:33436
oxoanion
chebi_ontology
oxoacid anions
oxoanions
CHEBI:35406
oxoanion
oxoanion
ChEBI
oxoacid anions
ChEBI
oxoanions
ChEBI
ortho-fused bicyclic arene
chebi_ontology
ortho-fused bicyclic arenes
CHEBI:35426
ortho-fused bicyclic arene
ortho-fused bicyclic arene
ChEBI
ortho-fused bicyclic arenes
ChEBI
ortho-fused polycyclic hydrocarbon
chebi_ontology
ortho-fused polycyclic hydrocarbons
CHEBI:35427
ortho-fused polycyclic hydrocarbon
ortho-fused polycyclic hydrocarbon
ChEBI
ortho-fused polycyclic hydrocarbons
ChEBI
ortho-fused bicyclic hydrocarbon
chebi_ontology
ortho-fused bicyclic hydrocarbons
CHEBI:35428
ortho-fused bicyclic hydrocarbon
ortho-fused bicyclic hydrocarbon
ChEBI
ortho-fused bicyclic hydrocarbons
ChEBI
A substance used in the prophylaxis or therapy of infectious diseases.
chebi_ontology
anti-infective agents
anti-infective drugs
antiinfective agents
antiinfective drug
CHEBI:35441
antiinfective agent
anti-infective agents
ChEBI
anti-infective drugs
ChEBI
antiinfective agents
ChEBI
antiinfective drug
ChEBI
A substance used to treat or prevent parasitic infections.
Wikipedia:Antiparasitic
chebi_ontology
antiparasitic drugs
antiparasitics
parasiticides
CHEBI:35442
antiparasitic agent
antiparasitic drugs
ChEBI
antiparasitics
ChEBI
parasiticides
ChEBI
Substance intended to kill parasitic worms (helminths).
anthelminthic
chebi_ontology
anthelminthics
anthelmintic
anthelmintics
antihelminth
antihelmintico
vermifuge
CHEBI:35443
anthelminthic drug
anthelminthic
IUPAC
anthelminthics
ChEBI
anthelmintic
IUPAC
anthelmintics
ChEBI
antihelminth
ChEBI
antihelmintico
ChEBI
vermifuge
ChEBI
A substance used in the treatment or control of nematode infestations.
chebi_ontology
antinematodal agent
antinematodal drugs
antinematodals
CHEBI:35444
antinematodal drug
antinematodal agent
ChEBI
antinematodal drugs
ChEBI
antinematodals
ChEBI
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
chebi_ontology
CNS agent
CNS drugs
central nervous system agents
CHEBI:35470
central nervous system drug
CNS agent
ChEBI
CNS drugs
ChEBI
central nervous system agents
ChEBI
A loosely defined grouping of drugs that have effects on psychological function.
Wikipedia:Psychotropic_drug
chebi_ontology
psychoactive agent
psychoactive drugs
psychopharmaceuticals
psychotropic drugs
CHEBI:35471
psychotropic drug
psychoactive agent
ChEBI
psychoactive drugs
ChEBI
psychopharmaceuticals
ChEBI
psychotropic drugs
ChEBI
chebi_ontology
alkali metal salts
CHEBI:35479
alkali metal salt
alkali metal salts
ChEBI
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
chebi_ontology
CHEBI:35480
analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
chebi_ontology
CHEBI:35481
non-narcotic analgesic
An agent that promotes the excretion of urine through its effects on kidney function.
chebi_ontology
diuretics
CHEBI:35498
diuretic
diuretics
ChEBI
An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds.
chebi_ontology
addition compounds
CHEBI:35504
addition compound
addition compounds
ChEBI
heterocyclic parent hydrides
chebi_ontology
heterocyclic fundamental parent
heterocyclic organic fundamental parents
organic heterocyclic fundamental parents
CHEBI:35552
heterocyclic organic fundamental parent
heterocyclic parent hydrides
IUPAC
heterocyclic fundamental parent
ChEBI
heterocyclic organic fundamental parents
ChEBI
organic heterocyclic fundamental parents
ChEBI
Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds.
mancude-ring systems
chebi_ontology
mancude rings
mancunide-ring systems
CHEBI:35568
mancude ring
mancude-ring systems
IUPAC
mancude rings
ChEBI
mancunide-ring systems
IUPAC
chebi_ontology
mancude organic heterobicyclic parents
mancude-ring organic heterobicyclic parents
CHEBI:35570
mancude organic heterobicyclic parent
mancude organic heterobicyclic parents
ChEBI
mancude-ring organic heterobicyclic parents
ChEBI
chebi_ontology
mancude organic heterocyclic parents
mancude-ring organic heterocyclic parents
CHEBI:35571
mancude organic heterocyclic parent
mancude organic heterocyclic parents
ChEBI
mancude-ring organic heterocyclic parents
ChEBI
chebi_ontology
organic mancude parents
organic mancude-ring parents
CHEBI:35573
organic mancude parent
organic mancude parents
ChEBI
organic mancude-ring parents
ChEBI
A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines.
0
C5H4N4
120.112
120.04360
HMDB:HMDB0001366
KEGG:C15587
MetaCyc:PURINE
PMID:12865945
PMID:24088627
purine
chebi_ontology
CHEBI:35584
purine
PMID:12865945
Europe PMC
PMID:24088627
Europe PMC
purine
IUPAC
The 1H-tautomer of purine.
0
C5H4N4
InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
KDCGOANMDULRCW-UHFFFAOYSA-N
120.11210
120.04360
c1nc2c[nH]cnc2n1
Gmelin:2379911
1H-purine
chebi_ontology
CHEBI:35586
1H-purine
Gmelin:2379911
Gmelin
1H-purine
ChEBI
The 3H-tautomer of purine.
0
C5H4N4
InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
KDCGOANMDULRCW-UHFFFAOYSA-N
120.11222
120.04360
c1nc2cnc[nH]c2n1
PMID:6149478
PMID:7178185
PMID:7296170
Reaxys:1210196
3H-purine
chebi_ontology
CHEBI:35588
3H-purine
PMID:6149478
Europe PMC
PMID:7178185
Europe PMC
PMID:7296170
Europe PMC
Reaxys:1210196
Reaxys
3H-purine
IUPAC
The 9H-tautomer of purine.
0
C5H4N4
InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
KDCGOANMDULRCW-UHFFFAOYSA-N
120.11222
120.04360
c1ncc2nc[nH]c2n1
Beilstein:606899
CAS:120-73-0
Gmelin:3120
Wikipedia:Purine
9H-purine
chebi_ontology
CHEBI:35589
9H-purine
Beilstein:606899
Beilstein
CAS:120-73-0
NIST Chemistry WebBook
Gmelin:3120
Gmelin
9H-purine
IUPAC
9H-purine
UniProt
A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.
carbon oxoanion
chebi_ontology
carbon oxoanions
oxocarbon anion
oxocarbon anions
CHEBI:35604
carbon oxoanion
carbon oxoanion
ChEBI
carbon oxoanions
ChEBI
oxocarbon anion
ChEBI
oxocarbon anions
ChEBI
chebi_ontology
carbon oxoacids
oxoacids of carbon
CHEBI:35605
carbon oxoacid
carbon oxoacids
ChEBI
oxoacids of carbon
ChEBI
A substance that inhibits or prevents the proliferation of neoplasms.
chebi_ontology
anticancer agent
anticancer agents
antineoplastic
antineoplastic agents
cytostatic
CHEBI:35610
antineoplastic agent
anticancer agent
ChEBI
anticancer agents
ChEBI
antineoplastic
ChEBI
antineoplastic agents
ChEBI
cytostatic
ChEBI
Any ether in which the oxygen is attached to at least one aryl substituent.
chebi_ontology
CHEBI:35618
aromatic ether
A member of the class of naphthols carrying a single hydroxy substituent at C-1 or C-2. A closed class.
0
C10H8O
144.170
144.05751
CAS:1321-67-1
naphthalenol
naphthol
chebi_ontology
hydroxynaphthalene
CHEBI:35682
naphthol
CAS:1321-67-1
ChemIDplus
naphthalenol
IUPAC
naphthol
IUPAC
hydroxynaphthalene
ChEBI
An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
chebi_ontology
antiplatyhelmintic agent
antiplatyhelmintic drugs
CHEBI:35684
antiplatyhelmintic drug
antiplatyhelmintic agent
ChEBI
antiplatyhelmintic drugs
ChEBI
Any carboxylic acid containing two carboxy groups.
CHEBI:23692
CHEBI:36172
CHEBI:4501
KEGG:C02028
Dicarboxylic acid
chebi_ontology
dicarboxylic acids
CHEBI:35692
dicarboxylic acid
Dicarboxylic acid
KEGG_COMPOUND
dicarboxylic acids
ChEBI
dicarboxylic acid anion
chebi_ontology
dicarboxylic acid anions
CHEBI:35693
dicarboxylic acid anion
dicarboxylic acid anion
ChEBI
dicarboxylic acid anions
ChEBI
A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter.
CHEBI:23960
CHEBI:4859
KEGG:C00287
Wikipedia:Ester
Ester
chebi_ontology
esters
CHEBI:35701
ester
Ester
KEGG_COMPOUND
esters
ChEBI
An ether in which the oxygen atom is linked to two ethyl groups.
0
C4H10O
InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3
RTZKZFJDLAIYFH-UHFFFAOYSA-N
74.12160
74.07316
CCOCC
CHEBI:23991
CHEBI:31565
Beilstein:1696894
CAS:60-29-7
Drug_Central:4417
Gmelin:25444
KEGG:C13240
KEGG:D01772
PMID:24443836
Reaxys:1696894
Wikipedia:Diethyl_ether
1,1'-oxydiethane
Diethyl ether
FlyBase miscellaneous CV
chebi_ontology
1,1'-oxybisethane
3-oxapentane
Aether
Anesthetic ether
Diethylaether
Ether
Pronarcol
R-610
aether
aether pro narcosi
diethyl oxide
ethoxyethane
ethyl ether
ethyl oxide
CHEBI:35702
diethyl ether
Beilstein:1696894
Beilstein
CAS:60-29-7
ChemIDplus
CAS:60-29-7
KEGG COMPOUND
CAS:60-29-7
NIST Chemistry WebBook
Drug_Central:4417
DrugCentral
Gmelin:25444
Gmelin
PMID:24443836
Europe PMC
Reaxys:1696894
Reaxys
1,1'-oxydiethane
IUPAC
Diethyl ether
KEGG_COMPOUND
1,1'-oxybisethane
ChemIDplus
3-oxapentane
ChemIDplus
Aether
ChEBI
Anesthetic ether
KEGG_COMPOUND
Diethylaether
ChEBI
Ether
KEGG_COMPOUND
Pronarcol
NIST_Chemistry_WebBook
R-610
ChEBI
aether
NIST_Chemistry_WebBook
aether pro narcosi
ChEBI
diethyl oxide
ChemIDplus
ethoxyethane
ChemIDplus
ethyl ether
ChemIDplus
ethyl oxide
ChemIDplus
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
CHEBI:10074
CHEBI:27333
KEGG:C06708
Wikipedia:Xenobiotic
Xenobiotic
xenobiotic
xenobiotics
chebi_ontology
xenobiotic compounds
CHEBI:35703
xenobiotic
Xenobiotic
KEGG_COMPOUND
xenobiotic
IUPAC
xenobiotics
IUPAC
xenobiotic compounds
ChEBI
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
chebi_ontology
immunosuppressant
immunosuppressive agents
inmunosupresor
CHEBI:35705
immunosuppressive agent
immunosuppressant
ChEBI
immunosuppressive agents
ChEBI
inmunosupresor
ChEBI
A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied).
nitro compounds
chebi_ontology
CHEBI:35715
nitro compound
nitro compounds
IUPAC
A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.
-1
CO2R
44.01000
43.98983
[O-]C([*])=O
CHEBI:13657
CHEBI:25382
CHEBI:3407
KEGG:C00060
chebi_ontology
Carboxylate
Monocarboxylate
a monocarboxylate
monocarboxylates
monocarboxylic acid anions
CHEBI:35757
monocarboxylic acid anion
Carboxylate
KEGG_COMPOUND
Monocarboxylate
KEGG_COMPOUND
a monocarboxylate
UniProt
monocarboxylates
ChEBI
monocarboxylic acid anions
ChEBI
A phosphorus oxoanion that is the conjugate base of phosphoric acid.
chebi_ontology
Pi
phosphate
phosphate ions
CHEBI:35780
phosphate ion
Pi
ChEBI
phosphate
ChEBI
phosphate ions
ChEBI
Compounds having the nitroso group, -NO, attached to carbon, or to another element, most commonly nitrogen or oxygen.
chebi_ontology
nitroso compounds
CHEBI:35800
nitroso compound
nitroso compounds
ChEBI
0
NO
30.00614
29.99799
nitroso
chebi_ontology
-N=O
O=N-
CHEBI:35801
nitroso group
nitroso
IUPAC
-N=O
IUPAC
O=N-
IUPAC
N-Nitroso amines, compounds of the structure R2NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of N-nitrosoamine and, as such, does not require the N locant.
0
N2OR2
44.01280
44.00106
[*]N([*])N=O
Wikipedia:Nitrosamine
chebi_ontology
N-Nitroso amines
nitrosamines
CHEBI:35803
nitrosamine
N-Nitroso amines
IUPAC
nitrosamines
ChEBI
0
C2H6N2O
InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3
UMFJAHHVKNCGLG-UHFFFAOYSA-N
74.08192
74.04801
CN(C)N=O
CHEBI:21778
CHEBI:34874
CAS:62-75-9
KEGG:C14704
PPDB:1645
N-Nitrosodimethylamine
N-methyl-N-nitrosomethanamine
FlyBase miscellaneous CV
chebi_ontology
1,1-Dimethyl-2-oxohydrazine
DMN
Dimethylnitrosamine
Dimethylnitrosoamine
N,N-Dimethylnitrosamine
CHEBI:35807
N-nitrosodimethylamine
CAS:62-75-9
ChemIDplus
CAS:62-75-9
KEGG COMPOUND
CAS:62-75-9
NIST Chemistry WebBook
N-Nitrosodimethylamine
ChemIDplus
N-Nitrosodimethylamine
KEGG_COMPOUND
N-methyl-N-nitrosomethanamine
IUPAC
1,1-Dimethyl-2-oxohydrazine
NIST_Chemistry_WebBook
DMN
ChemIDplus
Dimethylnitrosamine
KEGG_COMPOUND
Dimethylnitrosoamine
ChemIDplus
N,N-Dimethylnitrosamine
ChemIDplus
Any antimicrobial drug which is used to treat or prevent protozoal infections.
Wikipedia:Antiprotozoal_agent
chebi_ontology
antiprotozoal agent
antiprotozoal agents
antiprotozoal drugs
CHEBI:35820
antiprotozoal drug
antiprotozoal agent
ChEBI
antiprotozoal agents
ChEBI
antiprotozoal drugs
ChEBI
chebi_ontology
imidazopyrimidines
CHEBI:35875
imidazopyrimidine
imidazopyrimidines
ChEBI
pnictogen hydride
chebi_ontology
pnictogen hydrides
CHEBI:35881
pnictogen hydride
pnictogen hydride
ChEBI
pnictogen hydrides
ChEBI
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
chebi_ontology
neurotransmitter agents
CHEBI:35942
neurotransmitter agent
neurotransmitter agents
ChEBI
A chloroalkane that is ethane in which one or more of the hydrogens is replaced by chlorine.
chebi_ontology
CHEBI:36016
chloroethanes
A drug used to treat or prevent microbial infections.
chebi_ontology
antimicrobial drugs
CHEBI:36043
antimicrobial drug
antimicrobial drugs
ChEBI
chebi_ontology
organic chloride salts
CHEBI:36094
organic chloride salt
organic chloride salts
ChEBI
Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).
CHEBI:13684
CHEBI:26517
Wikipedia:Quinone
quinone
quinones
chebi_ontology
Chinon
quinones
CHEBI:36141
quinone
quinone
IUPAC
quinones
IUPAC
Chinon
ChEBI
quinones
ChEBI
A compound in which two monosaccharides are joined by a glycosidic bond.
CHEBI:23844
CHEBI:4654
KEGG:C01911
Disaccharide
disaccharides
chebi_ontology
Disaccharid
Disacharid
disacarido
disacaridos
CHEBI:36233
disaccharide
Disaccharide
KEGG_COMPOUND
disaccharides
IUPAC
Disaccharid
ChEBI
Disacharid
ChEBI
disacarido
ChEBI
disacaridos
IUPAC
chebi_ontology
naphthalenesulfonic acids
CHEBI:36336
naphthalenesulfonic acid
naphthalenesulfonic acids
ChEBI
Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
chebi_ontology
leptons
CHEBI:36338
lepton
leptons
ChEBI
Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
chebi_ontology
baryons
CHEBI:36339
baryon
baryons
ChEBI
Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
fermion
chebi_ontology
fermions
CHEBI:36340
fermion
fermion
IUPAC
fermions
ChEBI
A particle smaller than an atom.
chebi_ontology
subatomic particles
CHEBI:36342
subatomic particle
subatomic particles
ChEBI
A subatomic particle known to have substructure (i.e. consisting of smaller particles).
chebi_ontology
composite particles
CHEBI:36343
composite particle
composite particles
ChEBI
Hadron is a subatomic particle which experiences the strong force.
chebi_ontology
hadrons
CHEBI:36344
hadron
hadrons
ChEBI
A nucleus or any of its constituents in any of their energy states.
nuclear particle
chebi_ontology
CHEBI:36347
nuclear particle
nuclear particle
IUPAC
Any molecular entity consisting of more than one atom.
chebi_ontology
polyatomic entities
CHEBI:36357
polyatomic entity
polyatomic entities
ChEBI
An ion consisting of more than one atom.
chebi_ontology
polyatomic ions
CHEBI:36358
polyatomic ion
polyatomic ions
ChEBI
chebi_ontology
CHEBI:36360
phosphorus oxoacids and derivatives
chebi_ontology
saturated heterocyclic parent hydride
saturated heterocyclic parent hydrides
saturated organic heterocyclic parents
CHEBI:36388
saturated organic heterocyclic parent
saturated heterocyclic parent hydride
ChEBI
saturated heterocyclic parent hydrides
ChEBI
saturated organic heterocyclic parents
ChEBI
chebi_ontology
saturated heteromonocyclic parent hydride
saturated heteromonocyclic parent hydrides
saturated organic heteromonocyclic parents
CHEBI:36389
saturated organic heteromonocyclic parent
saturated heteromonocyclic parent hydride
ChEBI
saturated heteromonocyclic parent hydrides
ChEBI
saturated organic heteromonocyclic parents
ChEBI
chebi_ontology
mancude organic heterotricyclic parents
mancude-ring organic heterotricyclic parents
CHEBI:36416
mancude organic heterotricyclic parent
mancude organic heterotricyclic parents
ChEBI
mancude-ring organic heterotricyclic parents
ChEBI
A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.
0
C13H9N
InChI=1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H
DZBUGLKDJFMEHC-UHFFFAOYSA-N
179.21730
179.07350
c1ccc2nc3ccccc3cc2c1
Beilstein:120200
CAS:260-94-6
Gmelin:143403
PMID:11924543
PMID:24416442
Reaxys:120200
Wikipedia:Acridine
acridine
chebi_ontology
10-azaanthracene
2,3,5,6-dibenzopyridine
2,3-benzoquinoline
9-azaanthracene
Akridin
acrydine
benzo[b]quinoline
dibenzo[b,e]pyridine
CHEBI:36420
acridine
Beilstein:120200
Beilstein
CAS:260-94-6
ChemIDplus
CAS:260-94-6
NIST Chemistry WebBook
Gmelin:143403
Gmelin
PMID:11924543
Europe PMC
PMID:24416442
Europe PMC
Reaxys:120200
Reaxys
acridine
IUPAC
10-azaanthracene
ChemIDplus
2,3,5,6-dibenzopyridine
ChemIDplus
2,3-benzoquinoline
ChemIDplus
9-azaanthracene
ChemIDplus
Akridin
NIST_Chemistry_WebBook
acrydine
NIST_Chemistry_WebBook
benzo[b]quinoline
NIST_Chemistry_WebBook
dibenzo[b,e]pyridine
NIST_Chemistry_WebBook
Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
carbonyl compounds
chebi_ontology
CHEBI:36586
carbonyl compound
carbonyl compounds
IUPAC
Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
oxo compounds
chebi_ontology
organic oxo compounds
CHEBI:36587
organic oxo compound
oxo compounds
IUPAC
organic oxo compounds
ChEBI
An organochlorine compound is a compound containing at least one carbon-chlorine bond.
Wikipedia:Organochloride
organochlorine compound
chebi_ontology
chloroorganic compounds
chlororganische Verbindungen
organochloride compound
organochloride compounds
organochlorine compounds
CHEBI:36683
organochlorine compound
organochlorine compound
ChEBI
chloroorganic compounds
ChEBI
chlororganische Verbindungen
ChEBI
organochloride compound
ChEBI
organochloride compounds
ChEBI
organochlorine compounds
ChEBI
A compound containing at least one carbon-halogen bond.
chebi_ontology
organohalogen compounds
CHEBI:36684
organohalogen compound
organohalogen compounds
ChEBI
heterotricyclic compound
heterotricyclic compounds
chebi_ontology
heterotricyclic compounds
CHEBI:36688
heterotricyclic compound
heterotricyclic compound
ChEBI
heterotricyclic compounds
IUPAC
heterotricyclic compounds
ChEBI
A bicyclic compound in which all the ring atoms are carbon.
chebi_ontology
carbobicyclic compounds
CHEBI:36785
carbobicyclic compound
carbobicyclic compounds
ChEBI
-1
chebi_ontology
monoanions
CHEBI:36830
monoanion
monoanions
ChEBI
chebi_ontology
CHEBI:36892
elemental fluorine
0
F
18.998
18.99840
chebi_ontology
atomic fluorine
CHEBI:36895
monoatomic fluorine
atomic fluorine
ChEBI
chebi_ontology
inorganic ions
CHEBI:36914
inorganic ion
inorganic ions
ChEBI
chebi_ontology
inorganic cations
CHEBI:36915
inorganic cation
inorganic cations
ChEBI
A monoatomic or polyatomic species having one or more elementary charges of the proton.
CHEBI:23058
CHEBI:3473
KEGG:C01373
Cation
cation
chebi_ontology
Kation
Kationen
cationes
cations
CHEBI:36916
cation
Cation
KEGG_COMPOUND
cation
ChEBI
cation
IUPAC
Kation
ChEBI
Kationen
ChEBI
cationes
ChEBI
cations
ChEBI
chalcocarbonic acid
chalcocarbonic acids
chebi_ontology
chalcocarbonic acids
CHEBI:36961
chalcocarbonic acid
chalcocarbonic acid
ChEBI
chalcocarbonic acids
IUPAC
chalcocarbonic acids
ChEBI
An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
organochalcogen compound
chebi_ontology
organochalcogen compounds
CHEBI:36962
organochalcogen compound
organochalcogen compound
ChEBI
organochalcogen compounds
ChEBI
An organochalcogen compound containing at least one carbon-oxygen bond.
PMID:17586126
organooxygen compound
chebi_ontology
organooxygen compounds
CHEBI:36963
organooxygen compound
PMID:17586126
Europe PMC
organooxygen compound
ChEBI
organooxygen compounds
ChEBI
amino-acid anion
chebi_ontology
amino acid anions
amino-acid anions
CHEBI:37022
amino-acid anion
amino-acid anion
ChEBI
amino acid anions
ChEBI
amino-acid anions
ChEBI
A compound containing at least one carbon-bromine bond.
chebi_ontology
bromoorganic compound
organobromine compounds
CHEBI:37141
organobromine compound
bromoorganic compound
ChEBI
organobromine compounds
ChEBI
An organofluorine compound is a compound containing at least one carbon-fluorine bond.
organofluorine compound
chebi_ontology
fluoroorganic compound
fluoroorganic compounds
fluoroorganics
fluororganische Verbindungen
organofluorine compounds
CHEBI:37143
organofluorine compound
organofluorine compound
ChEBI
fluoroorganic compound
ChEBI
fluoroorganic compounds
ChEBI
fluoroorganics
ChEBI
fluororganische Verbindungen
ChEBI
organofluorine compounds
ChEBI
chebi_ontology
organic hydrides
CHEBI:37175
organic hydride
organic hydrides
ChEBI
mononuclear parent hydrides
chebi_ontology
mononuclear hydride
mononuclear hydrides
CHEBI:37176
mononuclear parent hydride
mononuclear parent hydrides
IUPAC
mononuclear hydride
ChEBI
mononuclear hydrides
IUPAC
chebi_ontology
CHEBI:37246
elemental sodium
A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease.
chebi_ontology
CHEBI:37334
diagnostic imaging agent
chebi_ontology
CHEBI:37335
MRI contrast agent
chebi_ontology
CHEBI:37404
elemental copper
Any ether in which the oxygen atom forms part of a ring.
CHEBI:37406
cyclic ether
cyclic ethers
epoxy compounds
chebi_ontology
cyclic ethers
epoxy compounds
CHEBI:37407
cyclic ether
cyclic ether
IUPAC
cyclic ethers
IUPAC
epoxy compounds
IUPAC
cyclic ethers
ChEBI
epoxy compounds
ChEBI
A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid units.
CHEBI:24074
CHEBI:24076
folates
chebi_ontology
folate
folates
CHEBI:37445
folic acids
folates
IUPAC
folate
ChEBI
folates
ChEBI
An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
CHEBI:13800
CHEBI:13801
CHEBI:22209
CHEBI:2426
KEGG:C00174
Acid
acid
chebi_ontology
Saeure
Saeuren
acide
acido
acids
CHEBI:37527
acid
Acid
KEGG_COMPOUND
acid
IUPAC
Saeure
ChEBI
Saeuren
ChEBI
acide
IUPAC
acido
ChEBI
acids
ChEBI
A molecular entity consisting of two or more chemical elements.
chebi_ontology
chemical compound
heteroatomic molecular entities
CHEBI:37577
heteroatomic molecular entity
chemical compound
ChEBI
heteroatomic molecular entities
ChEBI
Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements.
Wikipedia:Halide
chebi_ontology
halides
CHEBI:37578
halide
halides
ChEBI
0
C21H25Cl2N3O
InChI=1S/C21H25Cl2N3O/c1-3-26(12-9-22)11-4-10-24-21-17-7-5-15(23)13-20(17)25-19-8-6-16(27-2)14-18(19)21/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,24,25)
OIFINQAUHKZSBV-UHFFFAOYSA-N
406.34822
405.13747
CCN(CCCl)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12
Beilstein:498343
N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine
chebi_ontology
CHEBI:37594
N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine
Beilstein:498343
Beilstein
N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine
IUPAC
0
C23H28Cl3N3O
InChI=1S/C23H28Cl3N3O/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28)
UKOBAUFLOGFCMV-UHFFFAOYSA-N
468.84614
467.12980
COc1ccc2nc3cc(Cl)ccc3c(NC(C)CCCN(CCCl)CCCl)c2c1
CHEBI:47635
Beilstein:56337
CAS:64046-79-3
N(1),N(1)-bis(2-chloroethyl)-N(4)-(6-chloro-2-methoxyacridin-9-yl)pentane-1,4-diamine
quinacrine mustard
FlyBase miscellaneous CV
chebi_ontology
CHEBI:37595
quinacrine mustard
Beilstein:56337
Beilstein
CAS:64046-79-3
ChemIDplus
N(1),N(1)-bis(2-chloroethyl)-N(4)-(6-chloro-2-methoxyacridin-9-yl)pentane-1,4-diamine
IUPAC
quinacrine mustard
ChemIDplus
Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
Wikipedia:Nitrogen_mustard
nitrogen mustards
FlyBase miscellaneous CV
chebi_ontology
nitrogen mustard compound
nitrogen mustard compounds
nitrogen mustards
CHEBI:37598
nitrogen mustard
nitrogen mustards
IUPAC
nitrogen mustard compound
ChEBI
nitrogen mustard compounds
ChEBI
nitrogen mustards
ChEBI
An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom.
0
CNOR3
42.01680
41.99799
[*]C(=O)N([*])[*]
CHEBI:35354
CHEBI:35355
carboxamides
chebi_ontology
carboxamides
primary carboxamide
CHEBI:37622
carboxamide
carboxamides
IUPAC
carboxamides
ChEBI
primary carboxamide
ChEBI
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
chebi_ontology
protein kinase inhibitors
CHEBI:37699
protein kinase inhibitor
protein kinase inhibitors
ChEBI
A straight chain alkane composed of 4 carbon atoms.
0
C4H10
InChI=1S/C4H10/c1-3-4-2/h3-4H2,1-2H3
IJDNQMDRQITEOD-UHFFFAOYSA-N
58.12220
58.07825
CCCC
CHEBI:22945
CHEBI:25462
CHEBI:44430
Beilstein:969129
CAS:106-97-8
Gmelin:1148
PDBeChem:NBU
PMID:24179026
Reaxys:969129
Wikipedia:Butane
butane
chebi_ontology
E 943a
E-943a
E943a
N-BUTANE
R-600
n-Butan
n-C4H10
n-butane
CHEBI:37808
butane
Beilstein:969129
Beilstein
CAS:106-97-8
ChemIDplus
CAS:106-97-8
NIST Chemistry WebBook
Gmelin:1148
Gmelin
PMID:24179026
Europe PMC
Reaxys:969129
Reaxys
butane
IUPAC
butane
UniProt
E 943a
ChEBI
E-943a
ChEBI
E943a
ChEBI
N-BUTANE
PDBeChem
R-600
ChEBI
n-Butan
ChEBI
n-C4H10
NIST_Chemistry_WebBook
n-butane
NIST_Chemistry_WebBook
sulfuric acid derivative
chebi_ontology
sulfuric acid derivatives
CHEBI:37826
sulfuric acid derivative
sulfuric acid derivative
ChEBI
sulfuric acid derivatives
ChEBI
A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid.
carboacyl groups
carboxylic acyl group
chebi_ontology
carboxylic acyl groups
CHEBI:37838
carboacyl group
carboacyl groups
IUPAC
carboxylic acyl group
IUPAC
carboxylic acyl groups
IUPAC
chebi_ontology
azacycloalkanes
CHEBI:37949
azacycloalkane
azacycloalkanes
ChEBI
chebi_ontology
Farbstoff
Farbstoffe
colorante
colorantes
dyes
teinture
teintures
CHEBI:37958
dye
Farbstoff
ChEBI
Farbstoffe
ChEBI
colorante
ChEBI
colorantes
ChEBI
dyes
ChEBI
teinture
ChEBI
teintures
ChEBI
A carbopolyclic compound comprising of three carbocyclic rings.
chebi_ontology
carbotricyclic compounds
CHEBI:38032
carbotricyclic compound
carbotricyclic compounds
ChEBI
chebi_ontology
aminonaphthalenes
CHEBI:38034
aminonaphthalene
aminonaphthalenes
ChEBI
chebi_ontology
mesylate salt
mesylate salts
methanesulfonate salts
CHEBI:38037
methanesulfonate salt
mesylate salt
ChEBI
mesylate salts
ChEBI
methanesulfonate salts
ChEBI
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
chebi_ontology
antimalarials
CHEBI:38068
antimalarial
antimalarials
ChEBI
Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
chebi_ontology
heterocyclic organonitrogen compounds
organonitrogen heterocyclic compounds
CHEBI:38101
organonitrogen heterocyclic compound
heterocyclic organonitrogen compounds
ChEBI
organonitrogen heterocyclic compounds
ChEBI
Compounds based on a triazine skeleton.
chebi_ontology
CHEBI:38102
triazines
Any organic heterocyclic compound containing at least one ring oxygen atom.
PMID:17134300
chebi_ontology
heterocyclic organooxygen compounds
organooxygen heterocyclic compounds
oxacycles
CHEBI:38104
oxacycle
PMID:17134300
Europe PMC
heterocyclic organooxygen compounds
ChEBI
organooxygen heterocyclic compounds
ChEBI
oxacycles
ChEBI
chebi_ontology
heterocyclic organosulfur compounds
organosulfur heterocyclic compounds
CHEBI:38106
organosulfur heterocyclic compound
heterocyclic organosulfur compounds
ChEBI
organosulfur heterocyclic compounds
ChEBI
chebi_ontology
organic heterotetracyclic compounds
CHEBI:38163
organic heterotetracyclic compound
organic heterotetracyclic compounds
ChEBI
CHEBI:25429
CHEBI:38075
chebi_ontology
organic heteropolycyclic compounds
CHEBI:38166
organic heteropolycyclic compound
organic heteropolycyclic compounds
ChEBI
chebi_ontology
triamino-1,3,5-triazines
CHEBI:38175
triamino-1,3,5-triazine
triamino-1,3,5-triazines
ChEBI
chebi_ontology
polycyclic heteroarenes
CHEBI:38180
polycyclic heteroarene
polycyclic heteroarenes
ChEBI
chebi_ontology
azirinopyrroloindoles
CHEBI:38303
azirinopyrroloindole
azirinopyrroloindoles
ChEBI
Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure).
chebi_ontology
CHEBI:38313
diazines
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
chebi_ontology
cholinergic agent
cholinergic drugs
cholinomimetic
CHEBI:38323
cholinergic drug
cholinergic agent
ChEBI
cholinergic drugs
ChEBI
cholinomimetic
ChEBI
A pyrimidine carrying one or more oxo substituents.
chebi_ontology
pyrimidones
CHEBI:38337
pyrimidone
pyrimidones
ChEBI
chebi_ontology
1-benzopyrans
CHEBI:38443
1-benzopyran
1-benzopyrans
ChEBI
A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
chebi_ontology
benzophenanthridine alkaloids
CHEBI:38517
benzophenanthridine alkaloid
benzophenanthridine alkaloids
ChEBI
chebi_ontology
benzophenanthridines
CHEBI:38518
benzophenanthridine
benzophenanthridines
ChEBI
Any agent that affects the transport of molecular entities across a biological membrane.
chebi_ontology
membrane transport modulators
CHEBI:38632
membrane transport modulator
membrane transport modulators
ChEBI
Any flavonoid with a 3,4-dihydro-2-aryl-2H-1-benzopyran skeleton and its substituted derivatives.
0
C15OR14
196.160
195.99491
[*]c1c([*])c([*])c(c([*])c1[*])C1([*])Oc2c([*])c([*])c([*])c([*])c2C([*])([*])C1([*])[*]
chebi_ontology
CHEBI:38672
flavans
chebi_ontology
inorganic sodium salts
CHEBI:38702
inorganic sodium salt
inorganic sodium salts
ChEBI
Any dianion containing at least one carboxy group.
carboxylic acid dianion
chebi_ontology
carboxylic acid dianions
CHEBI:38716
carboxylic acid dianion
carboxylic acid dianion
ChEBI
carboxylic acid dianions
ChEBI
Any methoxyflavanone that is flavanone substituted by a methoxy group.
chebi_ontology
monomethoxyflavanones
CHEBI:38738
monomethoxyflavanone
monomethoxyflavanones
ChEBI
A hydroxyflavanone carrying three hydroxy substituents.
chebi_ontology
trihydroxyflavanones
CHEBI:38739
trihydroxyflavanone
trihydroxyflavanones
ChEBI
Any hydroxyflavanone carrying two hydroxy substituents.
chebi_ontology
dihydroxyflavanones
CHEBI:38749
dihydroxyflavanone
dihydroxyflavanones
ChEBI
A compound having the nitro group (-NO2) attached to a nitrogen atom.
N-nitro compounds
chebi_ontology
CHEBI:38780
N-nitro compound
N-nitro compounds
IUPAC
0
C14H11N6O3
311.276
311.08926
CHEBI:37074
chebi_ontology
CHEBI:38793
pteroate
0
C14H12N6O3
312.284
312.09709
CHEBI:26378
CAS:119-24-4
DrugBank:DB04196
Pteroic acid
chebi_ontology
Pteroinsaeure
CHEBI:38794
pteroic acid
CAS:119-24-4
ChemIDplus
Pteroic acid
ChemIDplus
Pteroinsaeure
ChEBI
chebi_ontology
CHEBI:38795
pteroic acids
chebi_ontology
CHEBI:38796
pteroates
A membrane transport modulator that is able to regulate intracellular calcium levels.
chebi_ontology
calcium channel modulators
CHEBI:38808
calcium channel modulator
calcium channel modulators
ChEBI
chebi_ontology
RyR modulator
ryanodine receptor modulators
ryanodine-sensitive calcium channel modulator
ryanodine-sensitive calcium-release channel modulator
CHEBI:38809
ryanodine receptor modulator
RyR modulator
ChEBI
ryanodine receptor modulators
ChEBI
ryanodine-sensitive calcium channel modulator
ChEBI
ryanodine-sensitive calcium-release channel modulator
ChEBI
Substance which produces loss of feeling or sensation.
anaesthetic
chebi_ontology
Anaesthetika
Anaesthetikum
anaesthetics
anesthetic agent
anesthetic drug
anesthetics
CHEBI:38867
anaesthetic
anaesthetic
IUPAC
Anaesthetika
ChEBI
Anaesthetikum
ChEBI
anaesthetics
ChEBI
anesthetic agent
ChEBI
anesthetic drug
ChEBI
anesthetics
ChEBI
Substance that produces loss of consciousness.
general anaesthetic
chebi_ontology
Allgemeinanaesthetika
Allgemeinanaesthetikum
general anaesthetics
general anesthetics
CHEBI:38869
general anaesthetic
general anaesthetic
IUPAC
Allgemeinanaesthetika
ChEBI
Allgemeinanaesthetikum
ChEBI
general anaesthetics
ChEBI
general anesthetics
ChEBI
chebi_ontology
Inhalationsanaesthetika
Inhalationsanaesthetikum
Inhalationsnarkotika
Inhalationsnarkotikum
anesthetic gases
inhalation anesthetics
CHEBI:38870
inhalation anaesthetic
Inhalationsanaesthetika
ChEBI
Inhalationsanaesthetikum
ChEBI
Inhalationsnarkotika
ChEBI
Inhalationsnarkotikum
ChEBI
anesthetic gases
ChEBI
inhalation anesthetics
ChEBI
Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
chebi_ontology
antischistosoma
antischistosomal drug
schistosomicide
schistosomicide drugs
schistosomicides
CHEBI:38941
schistosomicide drug
antischistosoma
ChEBI
antischistosomal drug
ChEBI
schistosomicide
ChEBI
schistosomicide drugs
ChEBI
schistosomicides
ChEBI
Any alkylbenzene that is benzene substituted with one or more methyl groups.
chebi_ontology
methylbenzenes
CHEBI:38975
methylbenzene
methylbenzenes
ChEBI
A monocyclic arene that is benzene substituted with one or more alkyl groups.
alkylbenzene
chebi_ontology
Alkylbenzol
alkylbenzenes
CHEBI:38976
alkylbenzene
alkylbenzene
ChEBI
Alkylbenzol
ChEBI
alkylbenzenes
ChEBI
Any sulfur oxoacid derivative derived from sulfurous acid.
sulfurous acid derivative
chebi_ontology
CHEBI:39087
sulfurous acid derivative
sulfurous acid derivative
ChEBI
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
Bronsted acid
chebi_ontology
Bronsted-Saeure
acide de Bronsted
donneur d'hydron
hydron donor
CHEBI:39141
Bronsted acid
Bronsted acid
IUPAC
Bronsted-Saeure
ChEBI
acide de Bronsted
IUPAC
donneur d'hydron
IUPAC
hydron donor
IUPAC
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
Bronsted base
chebi_ontology
Bronsted-Base
accepteur d'hydron
base de Bronsted
hydron acceptor
CHEBI:39142
Bronsted base
Bronsted base
IUPAC
Bronsted-Base
ChEBI
accepteur d'hydron
IUPAC
base de Bronsted
IUPAC
hydron acceptor
IUPAC
A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
Lewis base
chebi_ontology
Lewis-Base
base de Lewis
donneur d'une paire d'electrons
electron donor
CHEBI:39144
Lewis base
Lewis base
IUPAC
Lewis-Base
ChEBI
base de Lewis
IUPAC
donneur d'une paire d'electrons
ChEBI
electron donor
ChEBI
An N-nitro compound that is guanidine in which one of the hydrogens is replaced by a nitro group. It can exist in distinct tautomeric forms, as 1-nitroguanidine (a nitroimine) or 2-nitroguanidine (a nitroamine); in both solid and in solution, the nitroimine form predominates.
0
CH4N4O2
104.068
104.03343
CAS:556-88-7
Wikipedia:Nitroguanidine
nitroguanidine
chebi_ontology
picrite
CHEBI:39179
nitroguanidine
CAS:556-88-7
ChemIDplus
CAS:556-88-7
NIST Chemistry WebBook
nitroguanidine
IUPAC
picrite
NIST_Chemistry_WebBook
Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives.
chebi_ontology
CHEBI:39201
phenazines
chebi_ontology
dibenzopyridines
CHEBI:39206
dibenzopyridine
dibenzopyridines
ChEBI
A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms.
Wikipedia:Fumigation
chebi_ontology
fumigant pesticide
fumigants
CHEBI:39276
fumigant
fumigant pesticide
ChEBI
fumigants
ChEBI
Any saturated fatty acid lacking a side-chain.
PMID:15644336
straight-chain saturated fatty acid
chebi_ontology
straight-chain saturated fatty acids
CHEBI:39418
straight-chain saturated fatty acid
PMID:15644336
Europe PMC
straight-chain saturated fatty acid
ChEBI
straight-chain saturated fatty acids
ChEBI
CHEBI:13784
CHEBI:26445
CHEBI:7263
chebi_ontology
CHEBI:39446
pyrimidine ribonucleosides
Any compound having a pyrimidine as part of its structure.
CHEBI:13681
CHEBI:26448
chebi_ontology
CHEBI:39447
pyrimidines
A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated.
-1
H2O4P
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
NBIIXXVUZAFLBC-UHFFFAOYSA-M
96.98724
96.96962
[H]OP([O-])(=O)O[H]
CHEBI:29137
CHEBI:39739
DrugBank:DB02831
Gmelin:1999
PDBeChem:2HP
dihydrogen(tetraoxidophosphate)(1-)
dihydrogenphosphate
dihydrogentetraoxophosphate(1-)
dihydrogentetraoxophosphate(V)
dihydroxidodioxidophosphate(1-)
chebi_ontology
DIHYDROGENPHOSPHATE ION
H2PO4(-)
[PO2(OH)2](-)
CHEBI:39745
dihydrogenphosphate
Gmelin:1999
Gmelin
dihydrogen(tetraoxidophosphate)(1-)
IUPAC
dihydrogenphosphate
IUPAC
dihydrogentetraoxophosphate(1-)
IUPAC
dihydrogentetraoxophosphate(V)
IUPAC
dihydroxidodioxidophosphate(1-)
IUPAC
DIHYDROGENPHOSPHATE ION
PDBeChem
H2PO4(-)
IUPAC
[PO2(OH)2](-)
IUPAC
KEGG:C02019
Cyclic ketone
cyclic ketones
chebi_ontology
CHEBI:3992
cyclic ketone
Cyclic ketone
KEGG_COMPOUND
cyclic ketones
IUPAC
A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16degreeC) with a high boiling point (230degreeC), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF).
0
C4H10O2
InChI=1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2
WERYXYBDKMZEQL-UHFFFAOYSA-N
90.12100
90.06808
OCCCCO
CAS:110-63-4
DrugBank:DB01955
PDBeChem:BU1
PMID:11803699
PMID:15298490
PMID:16193534
PMID:17854202
PMID:18203723
PMID:19915428
PMID:20112336
PMID:21548140
PMID:21602812
Reaxys:1633445
Wikipedia:1,4-Butanediol
butane-1,4-diol
chebi_ontology
1,4-BD
1,4-BUTANEDIOL
1,4-butylene glycol
1,4-dihydroxybutane
1,4-tetramethylene glycol
HO(CH2)4OH
HOCH2CH2CH2CH2OH
tetramethylene 1,4-diol
tetramethylene glycol
CHEBI:41189
butane-1,4-diol
CAS:110-63-4
ChemIDplus
CAS:110-63-4
NIST Chemistry WebBook
PMID:11803699
Europe PMC
PMID:15298490
Europe PMC
PMID:16193534
Europe PMC
PMID:17854202
Europe PMC
PMID:18203723
Europe PMC
PMID:19915428
Europe PMC
PMID:20112336
Europe PMC
PMID:21548140
Europe PMC
PMID:21602812
Europe PMC
Reaxys:1633445
Reaxys
butane-1,4-diol
IUPAC
1,4-BD
ChemIDplus
1,4-BUTANEDIOL
PDBeChem
1,4-butylene glycol
ChemIDplus
1,4-dihydroxybutane
ChemIDplus
1,4-tetramethylene glycol
ChemIDplus
HO(CH2)4OH
ChEBI
HOCH2CH2CH2CH2OH
ChEBI
tetramethylene 1,4-diol
ChemIDplus
tetramethylene glycol
ChemIDplus
-2
CO3
InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
BVKZGUZCCUSVTD-UHFFFAOYSA-L
60.00890
59.98584
[O-]C([O-])=O
CHEBI:29201
CHEBI:41605
Beilstein:3600898
CAS:3812-32-6
Gmelin:1559
PDBeChem:CO3
carbonate
trioxidocarbonate(2-)
chebi_ontology
CARBONATE ION
CO3(2-)
Karbonat
[CO3](2-)
CHEBI:41609
carbonate
Beilstein:3600898
Beilstein
CAS:3812-32-6
ChemIDplus
Gmelin:1559
Gmelin
carbonate
IUPAC
trioxidocarbonate(2-)
IUPAC
CARBONATE ION
PDBeChem
CO3(2-)
ChEBI
Karbonat
ChEBI
[CO3](2-)
IUPAC
An alkane comprising of two carbon atoms.
0
C2H6
InChI=1S/C2H6/c1-2/h1-2H3
OTMSDBZUPAUEDD-UHFFFAOYSA-N
30.06904
30.04695
CC
CHEBI:23975
CHEBI:42260
Beilstein:1730716
CAS:74-84-0
Gmelin:212
PDBeChem:EHN
PMID:12826252
PMID:14664856
PMID:16236899
Reaxys:1730716
Wikipedia:Ethane
ETHANE
ethane
chebi_ontology
Aethan
C2H6
CH3-CH3
Ethan
R-170
bimethyl
dimethyl
ethyl hydride
methylmethane
CHEBI:42266
ethane
Beilstein:1730716
Beilstein
CAS:74-84-0
ChemIDplus
CAS:74-84-0
NIST Chemistry WebBook
Gmelin:212
Gmelin
PMID:12826252
Europe PMC
PMID:14664856
Europe PMC
PMID:16236899
Europe PMC
Reaxys:1730716
Reaxys
ETHANE
PDBeChem
ethane
IUPAC
Aethan
ChEBI
C2H6
ChEBI
CH3-CH3
IUPAC
Ethan
ChEBI
R-170
ChEBI
bimethyl
NIST_Chemistry_WebBook
dimethyl
NIST_Chemistry_WebBook
ethyl hydride
NIST_Chemistry_WebBook
methylmethane
NIST_Chemistry_WebBook
0
CHO
29.01804
29.00274
CHEBI:24089
CHEBI:42480
PDBeChem:FOR
FORMYL GROUP
aldehyde group
carbaldehyde
formyl
chebi_ontology
-CH(O)
-CHO
Fo
H-CO-
methanoyl
CHEBI:42485
formyl group
FORMYL GROUP
PDBeChem
aldehyde group
IUPAC
carbaldehyde
IUPAC
formyl
IUPAC
-CH(O)
IUPAC
-CHO
IUPAC
Fo
CBN
H-CO-
IUPAC
methanoyl
IUPAC
An aminocarboxamidine, the parent compound of the guanidines.
0
CH5N3
InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)
ZRALSGWEFCBTJO-UHFFFAOYSA-N
59.07062
59.04835
NC(N)=N
CHEBI:24435
CHEBI:42816
Beilstein:506044
CAS:113-00-8
DrugBank:DB00536
Drug_Central:1344
Gmelin:100679
PDBeChem:GAI
PMID:8070089
Reaxys:506044
Wikipedia:Guanidine
GUANIDINE
guanidine
chebi_ontology
Gu
H2N-C(=NH)-NH2
aminomethanamidine
guanidin
iminourea
CHEBI:42820
guanidine
Beilstein:506044
Beilstein
CAS:113-00-8
ChemIDplus
CAS:113-00-8
NIST Chemistry WebBook
Drug_Central:1344
DrugCentral
Gmelin:100679
Gmelin
PMID:8070089
Europe PMC
Reaxys:506044
Reaxys
GUANIDINE
PDBeChem
guanidine
IUPAC
Gu
ChEBI
H2N-C(=NH)-NH2
IUPAC
aminomethanamidine
NIST_Chemistry_WebBook
guanidin
ChEBI
iminourea
NIST_Chemistry_WebBook
0
HO
17.00734
17.00274
CHEBI:24706
CHEBI:43171
PDBeChem:HYD
HYDROXY GROUP
hydroxy
hydroxy group
oxidanyl
chebi_ontology
-OH
hydroxyl
hydroxyl group
CHEBI:43176
hydroxy group
HYDROXY GROUP
PDBeChem
hydroxy
IUPAC
hydroxy group
UniProt
oxidanyl
IUPAC
-OH
IUPAC
hydroxyl
ChEBI
hydroxyl group
ChEBI
chebi_ontology
CHEBI:43254
(4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one
A phosphate ion that is the conjugate base of dihydrogenphosphate.
-2
HO4P
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
NBIIXXVUZAFLBC-UHFFFAOYSA-L
95.97930
95.96234
OP([O-])([O-])=O
CHEBI:29139
CHEBI:43470
Gmelin:1998
MolBase:1628
PDBeChem:IPS
PDBeChem:PI
hydrogen(tetraoxidophosphate)(2-)
hydrogenphosphate
hydrogentetraoxophosphate(2-)
hydrogentetraoxophosphate(V)
hydroxidotrioxidophosphate(2-)
chebi_ontology
HPO4(2-)
HYDROGENPHOSPHATE ION
INORGANIC PHOSPHATE GROUP
[P(OH)O3](2-)
[PO3(OH)](2-)
hydrogen phosphate
phosphate
CHEBI:43474
hydrogenphosphate
Gmelin:1998
Gmelin
hydrogen(tetraoxidophosphate)(2-)
IUPAC
hydrogenphosphate
IUPAC
hydrogentetraoxophosphate(2-)
IUPAC
hydrogentetraoxophosphate(V)
IUPAC
hydroxidotrioxidophosphate(2-)
IUPAC
HPO4(2-)
IUPAC
HYDROGENPHOSPHATE ION
PDBeChem
INORGANIC PHOSPHATE GROUP
PDBeChem
[P(OH)O3](2-)
MolBase
[PO3(OH)](2-)
IUPAC
hydrogen phosphate
ChEBI
phosphate
UniProt
-1
HO4S
InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1
QAOWNCQODCNURD-UHFFFAOYSA-M
97.07154
96.96010
[H]OS([O-])(=O)=O
CHEBI:29199
CHEBI:45693
Gmelin:2121
PDBeChem:SOH
hydrogen(tetraoxidosulfate)(1-)
hydrogensulfate
hydrogensulfate(1-)
hydrogentetraoxosulfate(1-)
hydrogentetraoxosulfate(VI)
hydroxidotrioxidosulfate(1-)
chebi_ontology
HSO4(-)
HYDROGEN SULFATE
[SO3(OH)](-)
CHEBI:45696
hydrogensulfate
Gmelin:2121
Gmelin
hydrogen(tetraoxidosulfate)(1-)
IUPAC
hydrogensulfate
IUPAC
hydrogensulfate(1-)
IUPAC
hydrogentetraoxosulfate(1-)
IUPAC
hydrogentetraoxosulfate(VI)
IUPAC
hydroxidotrioxidosulfate(1-)
IUPAC
HSO4(-)
IUPAC
HYDROGEN SULFATE
PDBeChem
[SO3(OH)](-)
IUPAC
0
O
15.99940
15.99491
CHEBI:29353
CHEBI:44607
PDBeChem:OXO
OXO GROUP
oxo
chebi_ontology
=O
CHEBI:46629
oxo group
OXO GROUP
PDBeChem
oxo
IUPAC
=O
IUPAC
A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
Wikipedia:Solvent
chebi_ontology
Loesungsmittel
solvant
solvents
CHEBI:46787
solvent
Loesungsmittel
ChEBI
solvant
ChEBI
solvents
ChEBI
Any ether carrying a hydroxy group at unspecified position.
hydroxyether
chebi_ontology
CHEBI:46789
hydroxyether
hydroxyether
ChEBI
A hydroxyether that is ethanol substituted by a methoxy group at position 2.
0
C3H8O2
InChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
XNWFRZJHXBZDAG-UHFFFAOYSA-N
76.09442
76.05243
COCCO
CHEBI:19677
CHEBI:44217
Beilstein:1731074
CAS:109-86-4
DrugBank:DB02806
Gmelin:81877
MetaCyc:2-METHOXYETHANOL
PDBeChem:MXE
PMID:11354470
PMID:24399739
PPDB:1639
Reaxys:1731074
Wikipedia:2-Methoxyethanol
2-METHOXYETHANOL
2-methoxyethanol
FlyBase miscellaneous CV
chebi_ontology
1-hydroxy-2-methoxyethane
2-hydroxyethyl methyl ether
2-methoxy-1-ethanol
3-oxa-1-butanol
HOCH2CH2OCH3
Methyl cellosolve
beta-methoxyethanol
methyl oxitol
monomethyl ethylene glycol ether
CHEBI:46790
2-methoxyethanol
Beilstein:1731074
ChemIDplus
CAS:109-86-4
ChemIDplus
CAS:109-86-4
NIST Chemistry WebBook
Gmelin:81877
Gmelin
PMID:11354470
Europe PMC
PMID:24399739
Europe PMC
Reaxys:1731074
Reaxys
2-METHOXYETHANOL
PDBeChem
2-methoxyethanol
IUPAC
1-hydroxy-2-methoxyethane
ChemIDplus
2-hydroxyethyl methyl ether
NIST_Chemistry_WebBook
2-methoxy-1-ethanol
ChemIDplus
3-oxa-1-butanol
ChemIDplus
HOCH2CH2OCH3
NIST_Chemistry_WebBook
Methyl cellosolve
ChemIDplus
beta-methoxyethanol
NIST_Chemistry_WebBook
methyl oxitol
ChemIDplus
monomethyl ethylene glycol ether
ChemIDplus
0
CHO2
45.01744
44.99765
CHEBI:23025
CHEBI:41420
PDBeChem:CBX
CARBOXY GROUP
carboxy
chebi_ontology
-C(O)OH
-CO2H
-COOH
carboxyl group
CHEBI:46883
carboxy group
CARBOXY GROUP
PDBeChem
carboxy
IUPAC
-C(O)OH
IUPAC
-CO2H
ChEBI
-COOH
IUPAC
carboxyl group
ChEBI
chebi_ontology
tetrahydrofuranols
CHEBI:47017
tetrahydrofuranol
tetrahydrofuranols
ChEBI
chebi_ontology
dihydroxytetrahydrofurans
CHEBI:47019
dihydroxytetrahydrofuran
dihydroxytetrahydrofurans
ChEBI
CHEBI:27220
CHEBI:36947
chebi_ontology
urea derivatives
CHEBI:47857
ureas
urea derivatives
ChEBI
A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
chebi_ontology
photosensitising agent
CHEBI:47868
photosensitizing agent
photosensitising agent
ChEBI
Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group.
CHEBI:13809
CHEBI:33553
chebi_ontology
alkanesulfonic acids
alkylsulfonic acids
CHEBI:47901
alkanesulfonic acid
alkanesulfonic acids
ChEBI
alkylsulfonic acids
ChEBI
Any member of the 'superclass' flavonoids whose skeleton is based on 1-benzopyran with an aryl substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds.
CHEBI:13638
CHEBI:24044
CHEBI:5077
KEGG:C01579
Wikipedia:Flavonoid
Flavonoid
chebi_ontology
2-aryl-1-benzopyran
2-aryl-1-benzopyrans
flavonoids
CHEBI:47916
flavonoid
Flavonoid
KEGG_COMPOUND
2-aryl-1-benzopyran
ChEBI
2-aryl-1-benzopyrans
ChEBI
flavonoids
ChEBI
Any hydroxyflavanone with a hydroxy substituent at position 3' of the phenyl ring.
MetaCyc:3-Hydroxy-Flavanones
chebi_ontology
CHEBI:48024
3'-hydroxyflavanones
chebi_ontology
Schwefeloxide
oxides of sulfur
sulfur oxides
CHEBI:48154
sulfur oxide
Schwefeloxide
ChEBI
oxides of sulfur
ChEBI
sulfur oxides
ChEBI
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
chebi_ontology
Desinfektionsmittel
desinfectant
disinfectants
disinfecting agent
CHEBI:48219
disinfectant
Desinfektionsmittel
ChEBI
desinfectant
ChEBI
disinfectants
ChEBI
disinfecting agent
ChEBI
A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
polar solvent
chebi_ontology
polar solvents
CHEBI:48354
polar solvent
polar solvent
IUPAC
polar solvents
ChEBI
chebi_ontology
CHEBI:48355
non-polar solvent
A polar solvent that is capable of acting as a hydron (proton) donor.
protogenic solvent
chebi_ontology
CHEBI:48356
protic solvent
protogenic solvent
IUPAC
chebi_ontology
CHEBI:48357
aprotic solvent
A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds.
dipolar aprotic solvent
chebi_ontology
CHEBI:48358
polar aprotic solvent
dipolar aprotic solvent
IUPAC
0
CH4N2O
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
XSQUKJJJFZCRTK-UHFFFAOYSA-N
60.05534
60.03236
NC(O)=N
Beilstein:773698
CAS:4744-36-9
carbamimidic acid
chebi_ontology
H2N-C(=NH)-OH
H2N-C(OH)=NH
HO-C(=NH)-NH2
Isoharnstoff
carbamimic acid
carbonamidimidic acid
isourea
pseudourea
CHEBI:48376
carbamimidic acid
Beilstein:773698
Beilstein
CAS:4744-36-9
ChemIDplus
carbamimidic acid
IUPAC
H2N-C(=NH)-OH
IUPAC
H2N-C(OH)=NH
IUPAC
HO-C(=NH)-NH2
IUPAC
Isoharnstoff
ChEBI
carbamimic acid
ChemIDplus
carbonamidimidic acid
IUPAC
isourea
ChemIDplus
pseudourea
ChemIDplus
Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH).
imidic acid
imidic acids
chebi_ontology
imidic acids
imino acids
CHEBI:48377
imidic acid
imidic acid
ChEBI
imidic acids
IUPAC
imidic acids
ChEBI
imino acids
IUPAC
carboximidic acid
carboximidic acids
chebi_ontology
carboximidic acids
CHEBI:48378
carboximidic acid
carboximidic acid
ChEBI
carboximidic acids
IUPAC
carboximidic acids
ChEBI
A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
isoureas
chebi_ontology
isoureas
CHEBI:48379
isourea
isoureas
IUPAC
isoureas
ChEBI
Esters or salts of methanesulfonic acid.
chebi_ontology
CHEBI:48544
methanesulfonates
A role played by a substance that can react readily with, and thereby eliminate, radicals.
chebi_ontology
free radical scavengers
free-radical scavenger
CHEBI:48578
radical scavenger
free radical scavengers
ChEBI
free-radical scavenger
ChEBI
Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
antagonist
chebi_ontology
antagonista
antagoniste
antagonists
CHEBI:48706
antagonist
antagonist
IUPAC
antagonista
ChEBI
antagoniste
ChEBI
antagonists
ChEBI
0
H2O3S
InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)
LSNNMFCWUKXFEE-UHFFFAOYSA-N
82.08008
81.97247
OS(O)=O
CHEBI:26837
CHEBI:9344
CAS:7782-99-2
Gmelin:1458
KEGG:C00094
KNApSAcK:C00019662
PDBeChem:SO3
UM-BBD_compID:c0348
Sulfurous acid
dihydrogen trioxosulfate
dihydroxidooxidosulfur
sulfurous acid
trioxosulfuric acid
chebi_ontology
H2SO3
S(O)(OH)2
Sulfite
[SO(OH)2]
acide sulfureux
acido sulfuroso
schweflige Saeure
sulphurous acid
CHEBI:48854
sulfurous acid
CAS:7782-99-2
ChemIDplus
Gmelin:1458
Gmelin
UM-BBD_compID:c0348
UM-BBD
Sulfurous acid
KEGG_COMPOUND
dihydrogen trioxosulfate
IUPAC
dihydroxidooxidosulfur
IUPAC
sulfurous acid
IUPAC
trioxosulfuric acid
IUPAC
H2SO3
IUPAC
S(O)(OH)2
IUPAC
Sulfite
KEGG_COMPOUND
[SO(OH)2]
IUPAC
acide sulfureux
ChEBI
acido sulfuroso
ChEBI
schweflige Saeure
ChemIDplus
sulphurous acid
ChemIDplus
chebi_ontology
CHEBI:48857
sulfite salt
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
chebi_ontology
Anticholinergika
Anticholinergikum
acetylcholine antagonists
acetylcholine receptor antagonist
agent anticholinergique
agente anticolinergico
agentes anticolinergicos
anticholinergic agents
anticholinergics
anticholinergiques
anticolinergicos
cholinergic-blocking agents
CHEBI:48873
cholinergic antagonist
Anticholinergika
ChEBI
Anticholinergikum
ChEBI
acetylcholine antagonists
ChEBI
acetylcholine receptor antagonist
IUPHAR
agent anticholinergique
ChEBI
agente anticolinergico
ChEBI
agentes anticolinergicos
ChEBI
anticholinergic agents
ChEBI
anticholinergics
ChEBI
anticholinergiques
ChEBI
anticolinergicos
ChEBI
cholinergic-blocking agents
ChEBI
Any L-alpha-amino acid carrying an N-acyl substituent.
0
C3H3NO3R2
101.061
101.01129
CHEBI:13240
CHEBI:7232
KEGG:C02850
chebi_ontology
N-Acyl-L-amino acid
CHEBI:48927
N-acyl-L-alpha-amino acid
N-Acyl-L-amino acid
KEGG_COMPOUND
0
H
InChI=1S/H
YZCKVEUIGOORGS-UHFFFAOYSA-N
1.00794
1.00783
[H]
CHEBI:24634
CHEBI:49636
WebElements:H
hydrogen
chebi_ontology
1H
H
Wasserstoff
hidrogeno
hydrogen
hydrogene
CHEBI:49637
hydrogen atom
hydrogen
IUPAC
1H
IUPAC
H
IUPAC
Wasserstoff
ChEBI
hidrogeno
ChEBI
hydrogen
ChEBI
hydrogene
ChEBI
A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups.
chebi_ontology
organic amino compounds
CHEBI:50047
organic amino compound
organic amino compounds
ChEBI
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
0
C2H5N3O2
InChI=1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)
ZRKWMRDKSOPRRS-UHFFFAOYSA-N
103.08012
103.03818
CN(N=O)C(N)=O
CHEBI:25565
CHEBI:34843
CHEBI:50101
Beilstein:1756040
CAS:684-93-5
KEGG:C14595
PMID:11479921
PMID:12767522
PMID:15990165
PMID:19181008
PMID:24441676
PMID:6243984
PMID:8098217
PMID:8603364
Wikipedia:N-Methyl-N-nitrosourea
1-methyl-1-nitrosourea
N-Methyl-N-nitrosourea
FlyBase miscellaneous CV
chebi_ontology
1-(aminocarbonyl)-1-methyl-2-oxohydrazine
1-nitroso-1-methylurea
MNU
Methylnitrosoharnstoff
Methylnitrosourea
N-Methyl-N-nitrosoharnstoff
N-Nitroso-N-methylharnstoff
N-methyl-N-nitrosocarbamide
N-methyl-N-nitrosouree
N-nitroso-N-methylcarbamide
N-nitroso-N-methylurea
N-nitroso-N-methyluree
N-nitrosomethylurea
NMH
NMU
methylnitrosouree
nitrosomethylurea
CHEBI:50102
N-methyl-N-nitrosourea
Beilstein:1756040
Beilstein
CAS:684-93-5
ChemIDplus
CAS:684-93-5
KEGG COMPOUND
CAS:684-93-5
NIST Chemistry WebBook
PMID:11479921
Europe PMC
PMID:12767522
Europe PMC
PMID:15990165
Europe PMC
PMID:19181008
Europe PMC
PMID:24441676
Europe PMC
PMID:6243984
Europe PMC
PMID:8098217
Europe PMC
PMID:8603364
Europe PMC
1-methyl-1-nitrosourea
IUPAC
N-Methyl-N-nitrosourea
KEGG_COMPOUND
1-(aminocarbonyl)-1-methyl-2-oxohydrazine
NIST_Chemistry_WebBook
1-nitroso-1-methylurea
ChemIDplus
MNU
ChemIDplus
Methylnitrosoharnstoff
ChEBI
Methylnitrosourea
KEGG_COMPOUND
N-Methyl-N-nitrosoharnstoff
ChEBI
N-Nitroso-N-methylharnstoff
ChEBI
N-methyl-N-nitrosocarbamide
ChemIDplus
N-methyl-N-nitrosouree
ChEBI
N-nitroso-N-methylcarbamide
NIST_Chemistry_WebBook
N-nitroso-N-methylurea
ChemIDplus
N-nitroso-N-methyluree
ChEBI
N-nitrosomethylurea
NIST_Chemistry_WebBook
NMH
ChemIDplus
NMU
ChemIDplus
methylnitrosouree
ChemIDplus
nitrosomethylurea
NIST_Chemistry_WebBook
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
CHEBI:76774
chebi_ontology
EC 3.1.4.* (phosphoric diester hydrolase) inhibitors
phosphodiesterase inhibitor
phosphodiesterase inhibitors
phosphoric diester hydrolase (EC 3.1.4.*) inhibitor
phosphoric diester hydrolase (EC 3.1.4.*) inhibitors
phosphoric diester hydrolase inhibitor
phosphoric diester hydrolase inhibitors
CHEBI:50218
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
EC 3.1.4.* (phosphoric diester hydrolase) inhibitors
ChEBI
phosphodiesterase inhibitor
ChEBI
phosphodiesterase inhibitors
ChEBI
phosphoric diester hydrolase (EC 3.1.4.*) inhibitor
ChEBI
phosphoric diester hydrolase (EC 3.1.4.*) inhibitors
ChEBI
phosphoric diester hydrolase inhibitor
ChEBI
phosphoric diester hydrolase inhibitors
ChEBI
Any protective agent counteracting or neutralizing the action of poisons.
chebi_ontology
antidotes
CHEBI:50247
antidote
antidotes
ChEBI
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
PMID:23993918
PMID:23998799
PMID:24329110
PMID:24628402
PMID:24709544
PMID:25144792
PMID:25157234
PMID:25269430
PMID:25391982
PMID:25591121
PMID:25620096
PMID:25795057
PMID:26028253
PMID:26184144
PMID:28070577
PMID:28215138
PMID:28219047
PMID:28259775
PMID:28319647
PMID:28329729
PMID:28334528
Wikipedia:Prodrug
chebi_ontology
Prodrugs
CHEBI:50266
prodrug
PMID:23993918
Europe PMC
PMID:23998799
Europe PMC
PMID:24329110
Europe PMC
PMID:24628402
Europe PMC
PMID:24709544
Europe PMC
PMID:25144792
Europe PMC
PMID:25157234
Europe PMC
PMID:25269430
Europe PMC
PMID:25391982
Europe PMC
PMID:25591121
Europe PMC
PMID:25620096
Europe PMC
PMID:25795057
Europe PMC
PMID:26028253
Europe PMC
PMID:26184144
Europe PMC
PMID:28070577
Europe PMC
PMID:28215138
Europe PMC
PMID:28219047
Europe PMC
PMID:28259775
Europe PMC
PMID:28319647
Europe PMC
PMID:28329729
Europe PMC
PMID:28334528
Europe PMC
Prodrugs
ChEBI
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
chebi_ontology
chemoprotectant
chemoprotectants
chemoprotective agent
chemoprotective agents
protective agents
CHEBI:50267
protective agent
chemoprotectant
ChEBI
chemoprotectants
ChEBI
chemoprotective agent
ChEBI
chemoprotective agents
ChEBI
protective agents
ChEBI
A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
chebi_ontology
DNA topoisomerase inhibitor
DNA topoisomerase inhibitors
EC 5.99.1.2 (DNA topoisomerase) inhibitors
EC 5.99.1.2 (topoisomerase I) inhibitor
EC 5.99.1.2 (topoisomerase I) inhibitors
EC 5.99.1.2 inhibitor
EC 5.99.1.2 inhibitors
topoisomerase I (EC 5.99.1.2) inhibitor
topoisomerase I (EC 5.99.1.2) inhibitors
topoisomerase I inhibitor
topoisomerase I inhibitors
type I DNA topoisomerase inhibitor
type I DNA topoisomerase inhibitors
CHEBI:50276
EC 5.99.1.2 (DNA topoisomerase) inhibitor
DNA topoisomerase inhibitor
ChEBI
DNA topoisomerase inhibitors
ChEBI
EC 5.99.1.2 (DNA topoisomerase) inhibitors
ChEBI
EC 5.99.1.2 (topoisomerase I) inhibitor
ChEBI
EC 5.99.1.2 (topoisomerase I) inhibitors
ChEBI
EC 5.99.1.2 inhibitor
ChEBI
EC 5.99.1.2 inhibitors
ChEBI
topoisomerase I (EC 5.99.1.2) inhibitor
ChEBI
topoisomerase I (EC 5.99.1.2) inhibitors
ChEBI
topoisomerase I inhibitor
ChEBI
topoisomerase I inhibitors
ChEBI
type I DNA topoisomerase inhibitor
ChEBI
type I DNA topoisomerase inhibitors
ChEBI
chebi_ontology
canonical nucleotide residues
CHEBI:50297
canonical nucleotide residue
canonical nucleotide residues
ChEBI
chebi_ontology
canonical deoxyribonucleotide residues
CHEBI:50298
canonical deoxyribonucleotide residue
canonical deoxyribonucleotide residues
ChEBI
chebi_ontology
CHEBI:50312
onium compound
Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
onium cations
chebi_ontology
onium cations
onium ion
onium ions
CHEBI:50313
onium cation
onium cations
IUPAC
onium cations
ChEBI
onium ion
ChEBI
onium ions
ChEBI
+1
FH2
InChI=1S/FH2/h1H2/q+1
YNESUKSMQODWNS-UHFFFAOYSA-N
21.01428
21.01350
[H][F+][H]
fluoranium
fluoronium
chebi_ontology
H2F(+)
[FH2](+)
CHEBI:50314
fluoronium
fluoranium
IUPAC
fluoronium
IUPAC
H2F(+)
IUPAC
[FH2](+)
ChEBI
+1
ClH2
InChI=1S/ClH2/h1H2/q+1
IGJWHVUMEJASKV-UHFFFAOYSA-N
37.46858
36.98395
[H][Cl+][H]
Gmelin:331
chloranium
chloronium
chebi_ontology
H2Cl(+)
[ClH2](+)
CHEBI:50315
chloronium
Gmelin:331
Gmelin
chloranium
IUPAC
chloronium
IUPAC
H2Cl(+)
IUPAC
[ClH2](+)
IUPAC
chebi_ontology
nucleotide residues
CHEBI:50319
nucleotide residue
nucleotide residues
ChEBI
chebi_ontology
nucleoside residues
CHEBI:50320
nucleoside residue
nucleoside residues
ChEBI
A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid.
chebi_ontology
canonical amino-acid side-chain
canonical amino-acid side-chains
proteinogenic amino-acid side-chain
proteinogenic amino-acid side-chain groups
proteinogenic amino-acid side-chains
CHEBI:50325
proteinogenic amino-acid side-chain group
canonical amino-acid side-chain
ChEBI
canonical amino-acid side-chains
ChEBI
proteinogenic amino-acid side-chain
ChEBI
proteinogenic amino-acid side-chain groups
ChEBI
proteinogenic amino-acid side-chains
ChEBI
0
CH3S
47.10052
46.99555
sulfanylmethyl
chebi_ontology
-CH2-SH
HS-CH2-
cysteine side-chain
CHEBI:50326
sulfanylmethyl group
sulfanylmethyl
IUPAC
-CH2-SH
IUPAC
HS-CH2-
IUPAC
cysteine side-chain
ChEBI
0
C3H5O2
73.07060
73.02895
2-carboxyethyl
chebi_ontology
glutamic acid side-chain
CHEBI:50329
2-carboxyethyl group
2-carboxyethyl
IUPAC
glutamic acid side-chain
ChEBI
An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
Wikipedia:Dihydrofolate_reductase_inhibitor
chebi_ontology
7,8-dihydrofolate reductase inhibitor
7,8-dihydrofolate reductase inhibitors
DHFR inhibitor
DHFR inhibitors
EC 1.5.1.3 (dihydrofolate reductase) inhibitors
EC 1.5.1.3 inhibitor
EC 1.5.1.3 inhibitors
NADPH-dihydrofolate reductase inhibitor
NADPH-dihydrofolate reductase inhibitors
dihydrofolate reductase (EC 1.5.1.3) inhibitor
dihydrofolate reductase (EC 1.5.1.3) inhibitors
dihydrofolate reductase inhibitor
dihydrofolate reductase inhibitors
dihydrofolic acid reductase inhibitor
dihydrofolic acid reductase inhibitors
dihydrofolic reductase inhibitor
dihydrofolic reductase inhibitors
folic acid reductase inhibitor
folic acid reductase inhibitors
folic reductase inhibitor
folic reductase inhibitors
tetrahydrofolate dehydrogenase inhibitor
tetrahydrofolate dehydrogenase inhibitors
CHEBI:50683
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
7,8-dihydrofolate reductase inhibitor
ChEBI
7,8-dihydrofolate reductase inhibitors
ChEBI
DHFR inhibitor
ChEBI
DHFR inhibitors
ChEBI
EC 1.5.1.3 (dihydrofolate reductase) inhibitors
ChEBI
EC 1.5.1.3 inhibitor
ChEBI
EC 1.5.1.3 inhibitors
ChEBI
NADPH-dihydrofolate reductase inhibitor
ChEBI
NADPH-dihydrofolate reductase inhibitors
ChEBI
dihydrofolate reductase (EC 1.5.1.3) inhibitor
ChEBI
dihydrofolate reductase (EC 1.5.1.3) inhibitors
ChEBI
dihydrofolate reductase inhibitor
ChEBI
dihydrofolate reductase inhibitors
ChEBI
dihydrofolic acid reductase inhibitor
ChEBI
dihydrofolic acid reductase inhibitors
ChEBI
dihydrofolic reductase inhibitor
ChEBI
dihydrofolic reductase inhibitors
ChEBI
folic acid reductase inhibitor
ChEBI
folic acid reductase inhibitors
ChEBI
folic reductase inhibitor
ChEBI
folic reductase inhibitors
ChEBI
tetrahydrofolate dehydrogenase inhibitor
ChEBI
tetrahydrofolate dehydrogenase inhibitors
ChEBI
A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified.
chebi_ontology
cross-linking reagents
CHEBI:50684
cross-linking reagent
cross-linking reagents
ChEBI
A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues.
CHEBI:25679
CHEBI:35319
CHEBI:7758
KEGG:C00930
Oligosaccharide
oligosaccharides
chebi_ontology
O-glycosylglycoside
O-glycosylglycosides
oligosacarido
oligosacaridos
CHEBI:50699
oligosaccharide
Oligosaccharide
KEGG_COMPOUND
oligosaccharides
IUPAC
O-glycosylglycoside
ChEBI
O-glycosylglycosides
ChEBI
oligosacarido
ChEBI
oligosacaridos
IUPAC
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
chebi_ontology
Dietary Supplement
Food Supplementation
Nutritional supplement
CHEBI:50733
nutraceutical
Dietary Supplement
ChEBI
Food Supplementation
ChEBI
Nutritional supplement
ChEBI
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
CHEBI:132229
CHEBI:50234
chebi_ontology
DNA gyrase inhibitor
DNA gyrase inhibitors
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
DNA topoisomerase (ATP-hydrolysing) inhibitor
DNA topoisomerase (ATP-hydrolysing) inhibitors
DNA topoisomerase II inhibitor
DNA topoisomerase II inhibitors
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
EC 5.99.1.3 inhibitor
EC 5.99.1.3 inhibitors
inhibitor of type II topoisomerase
inhibitors of type II topoisomerase
topoisomerase II inhibitor
topoisomerase II inhibitors
topoisomerase-II inhibitor
topoisomerase-II inhibitors
type II DNA topoisomerase inhibitor
type II DNA topoisomerase inhibitors
CHEBI:50750
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
DNA gyrase inhibitor
ChEBI
DNA gyrase inhibitors
ChEBI
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
ChEBI
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
ChEBI
DNA topoisomerase (ATP-hydrolysing) inhibitor
ChEBI
DNA topoisomerase (ATP-hydrolysing) inhibitors
ChEBI
DNA topoisomerase II inhibitor
ChEBI
DNA topoisomerase II inhibitors
ChEBI
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
ChEBI
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
ChEBI
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
ChEBI
EC 5.99.1.3 inhibitor
ChEBI
EC 5.99.1.3 inhibitors
ChEBI
inhibitor of type II topoisomerase
ChEBI
inhibitors of type II topoisomerase
ChEBI
topoisomerase II inhibitor
ChEBI
topoisomerase II inhibitors
ChEBI
topoisomerase-II inhibitor
ChEBI
topoisomerase-II inhibitors
ChEBI
type II DNA topoisomerase inhibitor
ChEBI
type II DNA topoisomerase inhibitors
ChEBI
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
Wikipedia:Immunotherapy
chebi_ontology
Biomodulator
Immune factor
Immunologic factor
Immunological factor
immunomodulators
CHEBI:50846
immunomodulator
Biomodulator
ChEBI
Immune factor
ChEBI
Immunologic factor
ChEBI
Immunological factor
ChEBI
immunomodulators
ChEBI
Any molecular entity that contains carbon.
CHEBI:25700
CHEBI:33244
chebi_ontology
organic compounds
organic entity
organic molecular entities
CHEBI:50860
organic molecular entity
organic compounds
ChEBI
organic entity
ChEBI
organic molecular entities
ChEBI
chebi_ontology
azaarenes
CHEBI:50893
azaarene
azaarenes
ChEBI
A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Wikipedia:Genotoxicity
chebi_ontology
genotoxic agent
genotoxic agents
genotoxins
CHEBI:50902
genotoxin
genotoxic agent
ChEBI
genotoxic agents
ChEBI
genotoxins
ChEBI
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
chebi_ontology
agente carcinogeno
cancerigene
cancerogene
carcinogen
carcinogene
carcinogenic agents
carcinogeno
carcinogens
CHEBI:50903
carcinogenic agent
agente carcinogeno
ChEBI
cancerigene
ChEBI
cancerogene
ChEBI
carcinogen
ChEBI
carcinogene
ChEBI
carcinogenic agents
ChEBI
carcinogeno
ChEBI
carcinogens
ChEBI
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
Wikipedia:Allergen
chebi_ontology
alergeno
allergene
allergenic agent
CHEBI:50904
allergen
alergeno
ChEBI
allergene
ChEBI
allergenic agent
ChEBI
A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
chebi_ontology
agent teratogene
teratogen
teratogeno
CHEBI:50905
teratogenic agent
agent teratogene
ChEBI
teratogen
ChEBI
teratogeno
ChEBI
A role is particular behaviour which a material entity may exhibit.
chebi_ontology
CHEBI:50906
role
A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals.
chebi_ontology
agente hepatotoxico
hepatotoxic agents
hepatotoxicant
hepatotoxicants
hepatotoxin
hepatotoxins
hepatoxic agent
hepatoxicant
CHEBI:50908
hepatotoxic agent
agente hepatotoxico
ChEBI
hepatotoxic agents
ChEBI
hepatotoxicant
ChEBI
hepatotoxicants
ChEBI
hepatotoxin
ChEBI
hepatotoxins
ChEBI
hepatoxic agent
ChEBI
hepatoxicant
ChEBI
A poison that interferes with the functions of the nervous system.
CHEBI:50911
Wikipedia:Neurotoxin
chebi_ontology
agente neurotoxico
nerve poison
nerve poisons
neurotoxic agent
neurotoxic agents
neurotoxicant
neurotoxins
CHEBI:50910
neurotoxin
agente neurotoxico
ChEBI
nerve poison
ChEBI
nerve poisons
ChEBI
neurotoxic agent
ChEBI
neurotoxic agents
ChEBI
neurotoxicant
ChEBI
neurotoxins
ChEBI
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
CHEBI:75764
chebi_ontology
A-kinase inhibitor
A-kinase inhibitors
AP50 kinase inhibitor
AP50 kinase inhibitors
ATP-protein transphosphorylase inhibitor
ATP-protein transphosphorylase inhibitors
ATP:protein phosphotransferase (non-specific) inhibitor
ATP:protein phosphotransferase (non-specific) inhibitors
BR serine/threonine-protein kinase 2 inhibitor
BR serine/threonine-protein kinase 2 inhibitors
CK-2 inhibitor
CK-2 inhibitors
CKI inhibitor
CKI inhibitors
CKII inhibitor
CKII inhibitors
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors
EC 2.7.11.1 inhibitor
EC 2.7.11.1 inhibitors
HIPK2 inhibitor
HIPK2 inhibitors
Hpr kinase inhibitor
Hpr kinase inhibitors
M phase-specific cdc2 kinase inhibitor
M phase-specific cdc2 kinase inhibitors
MKNK2 inhibitor
MKNK2 inhibitors
PAK-1 inhibitor
PAK-1 inhibitors
PAK1 inhibitor
PAK1 inhibitors
PKA inhibitor
PKA inhibitors
Prp4 protein kinase inhibitor
Prp4 protein kinase inhibitors
Raf kinase inhibitor
Raf kinase inhibitors
Raf-1 inhibitor
Raf-1 inhibitors
STK32 inhibitor
STK32 inhibitors
T-antigen kinase inhibitor
T-antigen kinase inhibitors
WEE1Hu inhibitor
WEE1Hu inhibitors
Wee 1-like kinase inhibitor
Wee 1-like kinase inhibitors
Wee-kinase inhibitor
Wee-kinase inhibitors
betaIIPKC inhibitor
betaIIPKC inhibitors
cAMP-dependent protein kinase A inhibitor
cAMP-dependent protein kinase A inhibitors
cAMP-dependent protein kinase inhibitor
cAMP-dependent protein kinase inhibitors
cGMP-dependent protein kinase inhibitor
cGMP-dependent protein kinase inhibitors
calcium-dependent protein kinase C inhibitor
calcium-dependent protein kinase C inhibitors
calcium/phospholipid-dependent protein kinase inhibitor
calcium/phospholipid-dependent protein kinase inhibitors
casein kinase (phosphorylating) inhibitor
casein kinase (phosphorylating) inhibitors
casein kinase 2 inhibitor
casein kinase 2 inhibitors
casein kinase I inhibitor
casein kinase I inhibitors
casein kinase II inhibitor
casein kinase II inhibitors
casein kinase inhibitor
casein kinase inhibitors
cyclic AMP-dependent protein kinase A inhibitor
cyclic AMP-dependent protein kinase A inhibitors
cyclic AMP-dependent protein kinase inhibitor
cyclic AMP-dependent protein kinase inhibitors
cyclic monophosphate-dependent protein kinase inhibitor
cyclic monophosphate-dependent protein kinase inhibitors
cyclic nucleotide-dependent protein kinase inhibitor
cyclic nucleotide-dependent protein kinase inhibitors
cyclin-dependent kinase inhibitor
cyclin-dependent kinase inhibitors
dsk1 inhibitor
dsk1 inhibitors
epsilon PKC inhibitor
epsilon PKC inhibitors
glycogen synthase a kinase inhibitor
glycogen synthase a kinase inhibitors
glycogen synthase kinase inhibitor
glycogen synthase kinase inhibitors
hydroxyalkyl-protein kinase inhibitor
hydroxyalkyl-protein kinase inhibitors
mitogen-activated S6 kinase inhibitor
mitogen-activated S6 kinase inhibitors
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors
non-specific serine/threonine protein kinase inhibitor
non-specific serine/threonine protein kinase inhibitors
p21 activated kinase-1 inhibitor
p21 activated kinase-1 inhibitors
p82 kinase inhibitor
p82 kinase inhibitors
phosphorylase b kinase kinase inhibitor
phosphorylase b kinase kinase inhibitors
protein glutamyl kinase inhibitor
protein glutamyl kinase inhibitors
protein kinase (phosphorylating) inhibitor
protein kinase (phosphorylating) inhibitors
protein kinase A inhibitor
protein kinase A inhibitors
protein kinase CK2 inhibitor
protein kinase CK2 inhibitors
protein kinase p58 inhibitor
protein kinase p58 inhibitors
protein phosphokinase inhibitor
protein phosphokinase inhibitors
protein serine kinase inhibitor
protein serine kinase inhibitors
protein serine-threonine kinase inhibitor
protein serine-threonine kinase inhibitors
protein-aspartyl kinase inhibitor
protein-aspartyl kinase inhibitors
protein-cysteine kinase inhibitor
protein-cysteine kinase inhibitors
protein-serine kinase inhibitor
protein-serine kinase inhibitors
protein-serine/threonine kinase inhibitors
ribosomal S6 protein kinase inhibitor
ribosomal S6 protein kinase inhibitors
ribosomal protein S6 kinase II inhibitor
ribosomal protein S6 kinase II inhibitors
serine kinase inhibitor
serine kinase inhibitors
serine protein kinase inhibitor
serine protein kinase inhibitors
serine(threonine) protein kinase inhibitor
serine(threonine) protein kinase inhibitors
serine-specific protein kinase inhibitor
serine-specific protein kinase inhibitors
serine/threonine protein kinase inhibitor
serine/threonine protein kinase inhibitors
threonine-specific protein kinase inhibitor
threonine-specific protein kinase inhibitors
twitchin kinase inhibitor
twitchin kinase inhibitors
type-2 casein kinase inhibitor
type-2 casein kinase inhibitors
CHEBI:50925
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
A-kinase inhibitor
ChEBI
A-kinase inhibitors
ChEBI
AP50 kinase inhibitor
ChEBI
AP50 kinase inhibitors
ChEBI
ATP-protein transphosphorylase inhibitor
ChEBI
ATP-protein transphosphorylase inhibitors
ChEBI
ATP:protein phosphotransferase (non-specific) inhibitor
ChEBI
ATP:protein phosphotransferase (non-specific) inhibitors
ChEBI
BR serine/threonine-protein kinase 2 inhibitor
ChEBI
BR serine/threonine-protein kinase 2 inhibitors
ChEBI
CK-2 inhibitor
ChEBI
CK-2 inhibitors
ChEBI
CKI inhibitor
ChEBI
CKI inhibitors
ChEBI
CKII inhibitor
ChEBI
CKII inhibitors
ChEBI
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors
ChEBI
EC 2.7.11.1 inhibitor
ChEBI
EC 2.7.11.1 inhibitors
ChEBI
HIPK2 inhibitor
ChEBI
HIPK2 inhibitors
ChEBI
Hpr kinase inhibitor
ChEBI
Hpr kinase inhibitors
ChEBI
M phase-specific cdc2 kinase inhibitor
ChEBI
M phase-specific cdc2 kinase inhibitors
ChEBI
MKNK2 inhibitor
ChEBI
MKNK2 inhibitors
ChEBI
PAK-1 inhibitor
ChEBI
PAK-1 inhibitors
ChEBI
PAK1 inhibitor
ChEBI
PAK1 inhibitors
ChEBI
PKA inhibitor
ChEBI
PKA inhibitors
ChEBI
Prp4 protein kinase inhibitor
ChEBI
Prp4 protein kinase inhibitors
ChEBI
Raf kinase inhibitor
ChEBI
Raf kinase inhibitors
ChEBI
Raf-1 inhibitor
ChEBI
Raf-1 inhibitors
ChEBI
STK32 inhibitor
ChEBI
STK32 inhibitors
ChEBI
T-antigen kinase inhibitor
ChEBI
T-antigen kinase inhibitors
ChEBI
WEE1Hu inhibitor
ChEBI
WEE1Hu inhibitors
ChEBI
Wee 1-like kinase inhibitor
ChEBI
Wee 1-like kinase inhibitors
ChEBI
Wee-kinase inhibitor
ChEBI
Wee-kinase inhibitors
ChEBI
betaIIPKC inhibitor
ChEBI
betaIIPKC inhibitors
ChEBI
cAMP-dependent protein kinase A inhibitor
ChEBI
cAMP-dependent protein kinase A inhibitors
ChEBI
cAMP-dependent protein kinase inhibitor
ChEBI
cAMP-dependent protein kinase inhibitors
ChEBI
cGMP-dependent protein kinase inhibitor
ChEBI
cGMP-dependent protein kinase inhibitors
ChEBI
calcium-dependent protein kinase C inhibitor
ChEBI
calcium-dependent protein kinase C inhibitors
ChEBI
calcium/phospholipid-dependent protein kinase inhibitor
ChEBI
calcium/phospholipid-dependent protein kinase inhibitors
ChEBI
casein kinase (phosphorylating) inhibitor
ChEBI
casein kinase (phosphorylating) inhibitors
ChEBI
casein kinase 2 inhibitor
ChEBI
casein kinase 2 inhibitors
ChEBI
casein kinase I inhibitor
ChEBI
casein kinase I inhibitors
ChEBI
casein kinase II inhibitor
ChEBI
casein kinase II inhibitors
ChEBI
casein kinase inhibitor
ChEBI
casein kinase inhibitors
ChEBI
cyclic AMP-dependent protein kinase A inhibitor
ChEBI
cyclic AMP-dependent protein kinase A inhibitors
ChEBI
cyclic AMP-dependent protein kinase inhibitor
ChEBI
cyclic AMP-dependent protein kinase inhibitors
ChEBI
cyclic monophosphate-dependent protein kinase inhibitor
ChEBI
cyclic monophosphate-dependent protein kinase inhibitors
ChEBI
cyclic nucleotide-dependent protein kinase inhibitor
ChEBI
cyclic nucleotide-dependent protein kinase inhibitors
ChEBI
cyclin-dependent kinase inhibitor
ChEBI
cyclin-dependent kinase inhibitors
ChEBI
dsk1 inhibitor
ChEBI
dsk1 inhibitors
ChEBI
epsilon PKC inhibitor
ChEBI
epsilon PKC inhibitors
ChEBI
glycogen synthase a kinase inhibitor
ChEBI
glycogen synthase a kinase inhibitors
ChEBI
glycogen synthase kinase inhibitor
ChEBI
glycogen synthase kinase inhibitors
ChEBI
hydroxyalkyl-protein kinase inhibitor
ChEBI
hydroxyalkyl-protein kinase inhibitors
ChEBI
mitogen-activated S6 kinase inhibitor
ChEBI
mitogen-activated S6 kinase inhibitors
ChEBI
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor
ChEBI
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors
ChEBI
non-specific serine/threonine protein kinase inhibitor
ChEBI
non-specific serine/threonine protein kinase inhibitors
ChEBI
p21 activated kinase-1 inhibitor
ChEBI
p21 activated kinase-1 inhibitors
ChEBI
p82 kinase inhibitor
ChEBI
p82 kinase inhibitors
ChEBI
phosphorylase b kinase kinase inhibitor
ChEBI
phosphorylase b kinase kinase inhibitors
ChEBI
protein glutamyl kinase inhibitor
ChEBI
protein glutamyl kinase inhibitors
ChEBI
protein kinase (phosphorylating) inhibitor
ChEBI
protein kinase (phosphorylating) inhibitors
ChEBI
protein kinase A inhibitor
ChEBI
protein kinase A inhibitors
ChEBI
protein kinase CK2 inhibitor
ChEBI
protein kinase CK2 inhibitors
ChEBI
protein kinase p58 inhibitor
ChEBI
protein kinase p58 inhibitors
ChEBI
protein phosphokinase inhibitor
ChEBI
protein phosphokinase inhibitors
ChEBI
protein serine kinase inhibitor
ChEBI
protein serine kinase inhibitors
ChEBI
protein serine-threonine kinase inhibitor
ChEBI
protein serine-threonine kinase inhibitors
ChEBI
protein-aspartyl kinase inhibitor
ChEBI
protein-aspartyl kinase inhibitors
ChEBI
protein-cysteine kinase inhibitor
ChEBI
protein-cysteine kinase inhibitors
ChEBI
protein-serine kinase inhibitor
ChEBI
protein-serine kinase inhibitors
ChEBI
protein-serine/threonine kinase inhibitors
ChEBI
ribosomal S6 protein kinase inhibitor
ChEBI
ribosomal S6 protein kinase inhibitors
ChEBI
ribosomal protein S6 kinase II inhibitor
ChEBI
ribosomal protein S6 kinase II inhibitors
ChEBI
serine kinase inhibitor
ChEBI
serine kinase inhibitors
ChEBI
serine protein kinase inhibitor
ChEBI
serine protein kinase inhibitors
ChEBI
serine(threonine) protein kinase inhibitor
ChEBI
serine(threonine) protein kinase inhibitors
ChEBI
serine-specific protein kinase inhibitor
ChEBI
serine-specific protein kinase inhibitors
ChEBI
serine/threonine protein kinase inhibitor
ChEBI
serine/threonine protein kinase inhibitors
ChEBI
threonine-specific protein kinase inhibitor
ChEBI
threonine-specific protein kinase inhibitors
ChEBI
twitchin kinase inhibitor
ChEBI
twitchin kinase inhibitors
ChEBI
type-2 casein kinase inhibitor
ChEBI
type-2 casein kinase inhibitors
ChEBI
+1
C2H6N
InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2/p+1
NOWKCMXCCJGMRR-UHFFFAOYSA-O
44.07578
44.04948
C1C[NH2+]1
Gmelin:322803
aziridinium
chebi_ontology
aziridinium ion
CHEBI:50929
aziridinium
Gmelin:322803
Gmelin
aziridinium
IUPAC
aziridinium ion
ChEBI
Thioxanthene and its substitution derivatives.
chebi_ontology
CHEBI:50930
thioxanthenes
Compounds containing an aziridine ring that contains a quaternary nitrogen atom.
chebi_ontology
aziridinium ions
CHEBI:50946
aziridinium ion
aziridinium ions
ChEBI
A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups.
chebi_ontology
tertiary amino compounds
CHEBI:50996
tertiary amino compound
tertiary amino compounds
ChEBI
A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
0
C20H24N2OS
InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3
FBQPGGIHOFZRGH-UHFFFAOYSA-N
340.48200
340.16093
CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12
CHEBI:19039
CHEBI:6552
Beilstein:312369
CAS:479-50-5
DrugBank:DB04967
Drug_Central:1616
HMDB:HMDB0015607
KEGG:C11715
PMID:21148553
PMID:21935361
PMID:4368942
PMID:6887199
PMID:9169823
Reaxys:312369
Wikipedia:Lucanthone
1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
Lucanthone
FlyBase miscellaneous CV
chebi_ontology
1-((2-(diethylamino)ethyl)amino)-4-methylthioxanthen-9-one
1-diethylaminoethylethylamino-4-methyl-thioxanthenone
1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one
lucanthone
lucanthonum
lucantona
CHEBI:51052
lucanthone
Beilstein:312369
Beilstein
CAS:479-50-5
ChemIDplus
CAS:479-50-5
KEGG COMPOUND
Drug_Central:1616
DrugCentral
PMID:21148553
Europe PMC
PMID:21935361
Europe PMC
PMID:4368942
Europe PMC
PMID:6887199
Europe PMC
PMID:9169823
Europe PMC
Reaxys:312369
Reaxys
1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
IUPAC
Lucanthone
KEGG_COMPOUND
1-((2-(diethylamino)ethyl)amino)-4-methylthioxanthen-9-one
ChemIDplus
1-diethylaminoethylethylamino-4-methyl-thioxanthenone
ChEBI
1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one
ChEBI
lucanthone
ChemIDplus
lucanthone
WHO_MedNet
lucanthonum
ChemIDplus
lucantona
ChemIDplus
A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
chebi_ontology
hormone receptor modulators
CHEBI:51061
hormone receptor modulator
hormone receptor modulators
ChEBI
chebi_ontology
CHEBI:51067
tetraphenes
chebi_ontology
organic halide salts
CHEBI:51069
organic halide salt
organic halide salts
ChEBI
+1
C30H31N6
InChI=1S/C30H31N6/c1-5-35(6-2)26-17-19-28-30(21-26)36(25-10-8-7-9-11-25)29-20-23(14-18-27(29)31-28)33-32-22-12-15-24(16-13-22)34(3)4/h7-21H,5-6H2,1-4H3/q+1
TYOFQDFFFPHHNT-UHFFFAOYSA-N
475.60758
475.26047
CCN(CC)c1ccc2nc3ccc(cc3[n+](-c3ccccc3)c2c1)\N=N\c1ccc(cc1)N(C)C
Beilstein:9234599
3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium
chebi_ontology
CHEBI:51070
Janus Green B cation
Beilstein:9234599
Beilstein
3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium
IUPAC
A role played by the molecular entity or part thereof within a chemical context.
chebi_ontology
CHEBI:51086
chemical role
CHEBI:25556
CHEBI:7594
KEGG:C06061
chebi_ontology
Nitrogenous compounds
nitrogen compounds
nitrogen molecular entities
CHEBI:51143
nitrogen molecular entity
Nitrogenous compounds
KEGG_COMPOUND
nitrogen compounds
ChEBI
nitrogen molecular entities
ChEBI
nitrogen group
chebi_ontology
nitrogen groups
nitrogen-containing group
nitrogenous group
CHEBI:51144
nitrogen group
nitrogen group
ChEBI
nitrogen groups
ChEBI
nitrogen-containing group
ChEBI
nitrogenous group
ChEBI
An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case.
chebi_ontology
dipolar compounds
CHEBI:51151
dipolar compound
dipolar compounds
ChEBI
0
Cl2H6N2Pt
300.045
298.95559
CAS:14913-33-8
Gmelin:101110
diamminedichloridoplatinum
diamminedichloridoplatinum(II)
diamminedichloroplatinum
diamminedichloroplatinum(II)
chebi_ontology
diammine(dichloro)platinum
diammineplatinum dichloride
CHEBI:51214
diamminedichloroplatinum
CAS:14913-33-8
NIST Chemistry WebBook
Gmelin:101110
Gmelin
diamminedichloridoplatinum
IUPAC
diamminedichloridoplatinum(II)
IUPAC
diamminedichloroplatinum
IUPAC
diamminedichloroplatinum(II)
IUPAC
diammine(dichloro)platinum
ChEBI
diammineplatinum dichloride
NIST_Chemistry_WebBook
Sulfate salts where the cation is a metal ion.
chebi_ontology
metal sulfates
CHEBI:51336
metal sulfate
metal sulfates
ChEBI
An angular ortho-fused polycyclic arene consisting of four fused benzene rings.
0
C18H12
InChI=1S/C18H12/c1-2-7-15-12-18-16(11-14(15)6-1)10-9-13-5-3-4-8-17(13)18/h1-12H
DXBHBZVCASKNBY-UHFFFAOYSA-N
228.28788
228.09390
c1ccc2cc3c(ccc4ccccc34)cc2c1
CHEBI:33088
CHEBI:34557
Beilstein:1909298
CAS:56-55-3
Gmelin:244702
KEGG:C14317
PMID:25528193
PMID:25528488
PMID:26720419
PMID:7561049
Patent:DE481819
Patent:DE486766
Reaxys:1909298
Wikipedia:Tetraphene
tetraphene
chebi_ontology
1,2-Benzanthracene
1,2-Benzanthrazen
2,3-benzphenanthrene
Benz[a]anthracene
benzanthrene
naphthanthracene
CHEBI:51348
tetraphene
Beilstein:1909298
Beilstein
CAS:56-55-3
ChemIDplus
CAS:56-55-3
KEGG COMPOUND
CAS:56-55-3
NIST Chemistry WebBook
Gmelin:244702
Gmelin
PMID:25528193
Europe PMC
PMID:25528488
Europe PMC
PMID:26720419
Europe PMC
PMID:7561049
Europe PMC
Reaxys:1909298
Reaxys
tetraphene
IUPAC
1,2-Benzanthracene
KEGG_COMPOUND
1,2-Benzanthrazen
ChemIDplus
2,3-benzphenanthrene
ChemIDplus
Benz[a]anthracene
KEGG_COMPOUND
benzanthrene
NIST_Chemistry_WebBook
naphthanthracene
ChemIDplus
Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
chebi_ontology
organodiyl groups
CHEBI:51422
organodiyl group
organodiyl groups
ChEBI
chebi_ontology
CHEBI:51446
organic divalent group
chebi_ontology
CHEBI:51447
organic univalent group
A carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid.
CHEBI:21653
CHEBI:22226
chebi_ontology
N-acyl amino acid
N-acyl amino acids
N-acyl-amino-acid
N-acyl-amino-acids
N-acylamino acid
N-acylamino acids
acyl-amino-acid
acyl-amino-acids
acylamino acids
CHEBI:51569
N-acyl-amino acid
N-acyl amino acid
ChEBI
N-acyl amino acids
ChEBI
N-acyl-amino-acid
ChEBI
N-acyl-amino-acids
ChEBI
N-acylamino acid
ChEBI
N-acylamino acids
ChEBI
acyl-amino-acid
ChEBI
acyl-amino-acids
ChEBI
acylamino acids
ChEBI
Acridines which are substituted in any position by one or more amino groups or substituted amino groups. Note that the term 'aminoacridine' is the International Prorietary Name (INN) for 9-aminoacridine.
chebi_ontology
aminoacridine
CHEBI:51803
aminoacridines
aminoacridine
ChEBI
chebi_ontology
organic polycyclic compounds
CHEBI:51958
organic polycyclic compound
organic polycyclic compounds
ChEBI
chebi_ontology
organic tricyclic compounds
CHEBI:51959
organic tricyclic compound
organic tricyclic compounds
ChEBI
A biological role played by the molecular entity or part thereof within a biochemical context.
chebi_ontology
CHEBI:52206
biochemical role
chebi_ontology
CHEBI:52208
biophysical role
A role played by the molecular entity or part thereof which causes the development of a pathological process.
chebi_ontology
etiopathogenetic agent
etiopathogenetic role
CHEBI:52209
aetiopathogenetic role
etiopathogenetic agent
ChEBI
etiopathogenetic role
ChEBI
A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
chebi_ontology
CHEBI:52210
pharmacological role
chebi_ontology
CHEBI:52211
physiological role
Any substance introduced into a living organism with therapeutic or diagnostic purpose.
CHEBI:33293
CHEBI:33294
chebi_ontology
farmaco
medicament
pharmaceuticals
CHEBI:52217
pharmaceutical
farmaco
ChEBI
medicament
ChEBI
pharmaceuticals
ChEBI
A member of the class of butanediols that is butane in which two of the hydrogens have been replaced by hydroxy groups.
butanediol
chebi_ontology
butanediols
CHEBI:52684
butanediol
butanediol
IUPAC
butanediols
ChEBI
A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
0
C20H24N2O2S
InChI=1S/C20H24N2O2S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20/h5-10,21,23H,3-4,11-13H2,1-2H3
MFZWMTSUNYWVBU-UHFFFAOYSA-N
356.48200
356.15585
CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12
Beilstein:1402722
CAS:3105-97-3
Drug_Central:1383
KEGG:D00541
LINCS:LSM-5614
PMID:1888160
PMID:21935361
PMID:2957147
PMID:5573958
PMID:626982
PMID:7369442
Patent:NL6410359
Patent:US3294803
Patent:US3312598
Reaxys:1402722
Wikipedia:Hycanthone
1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one
Hycanthone
chebi_ontology
1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one
1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one
Hycanthon
Lucanthone metabolite
hicantona
hycanthone
hycanthonum
CHEBI:52768
hycanthone
Beilstein:1402722
Beilstein
CAS:3105-97-3
ChemIDplus
CAS:3105-97-3
KEGG DRUG
Drug_Central:1383
DrugCentral
PMID:1888160
Europe PMC
PMID:21935361
Europe PMC
PMID:2957147
Europe PMC
PMID:5573958
Europe PMC
PMID:626982
Europe PMC
PMID:7369442
Europe PMC
Reaxys:1402722
Reaxys
1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one
IUPAC
Hycanthone
KEGG_DRUG
1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one
ChemIDplus
1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
ChemIDplus
1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one
ChEBI
Hycanthon
ChemIDplus
Lucanthone metabolite
ChemIDplus
hicantona
ChemIDplus
hycanthone
KEGG_DRUG
hycanthone
WHO_MedNet
hycanthonum
ChemIDplus
An antagonist at the A2A receptor.
Wikipedia:Adenosine_A2A_receptor
chebi_ontology
adenosine A2A receptor antagonists
CHEBI:53121
adenosine A2A receptor antagonist
adenosine A2A receptor antagonists
ChEBI
A cyclic compound having as ring members atoms of at least two different elements.
Heterocyclic compound
chebi_ontology
compuesto heterociclico
compuestos heterociclicos
heterocycle
heterocyclic compounds
CHEBI:5686
heterocyclic compound
Heterocyclic compound
KEGG_COMPOUND
compuesto heterociclico
IUPAC
compuestos heterociclicos
IUPAC
heterocycle
ChEBI
heterocyclic compounds
ChEBI
A D-alpha-amino acid zwitterion that is D-phenylalanine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3.
0
C9H11NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
COLNVLDHVKWLRT-MRVPVSSYSA-N
165.18910
165.07898
[NH3+][C@H](Cc1ccccc1)C([O-])=O
MetaCyc:CPD-216
(2R)-2-azaniumyl-3-phenylpropanoate
chebi_ontology
(2R)-2-ammonio-3-phenylpropanoate
D-phenylalanine
CHEBI:57981
D-phenylalanine zwitterion
(2R)-2-azaniumyl-3-phenylpropanoate
IUPAC
(2R)-2-ammonio-3-phenylpropanoate
IUPAC
D-phenylalanine
UniProt
An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-phenylalanine; major species at pH 7.3.
0
C9H11NO2
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
COLNVLDHVKWLRT-QMMMGPOBSA-N
165.18910
165.07898
[NH3+][C@@H](Cc1ccccc1)C([O-])=O
MetaCyc:PHE
PMID:21956539
(2S)-2-azaniumyl-3-phenylpropanoate
chebi_ontology
(2S)-2-ammonio-3-phenylpropanoate
L-phenylalanine
phenylalanine
CHEBI:58095
L-phenylalanine zwitterion
PMID:21956539
Europe PMC
(2S)-2-azaniumyl-3-phenylpropanoate
IUPAC
(2S)-2-ammonio-3-phenylpropanoate
IUPAC
L-phenylalanine
UniProt
phenylalanine
ChEBI
Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6).
-1
CO2R
44.010
43.98983
[O-]C([*])=O
chebi_ontology
a short-chain fatty acid
short-chain fatty acid anions
CHEBI:58951
short-chain fatty acid anion
a short-chain fatty acid
UniProt
short-chain fatty acid anions
ChEBI
Any fatty acid anion in which there is no C-C unsaturation.
chebi_ontology
saturated fatty acid anions
CHEBI:58953
saturated fatty acid anion
saturated fatty acid anions
ChEBI
Any saturated fatty acid anion lacking a carbon side-chain.
chebi_ontology
straight-chain saturated fatty acid anions
CHEBI:58954
straight-chain saturated fatty acid anion
straight-chain saturated fatty acid anions
ChEBI
An organic anion of general formula RS(=O)2O(-) where R is an organyl group.
-1
O4SR
96.06300
95.95173
[O-]S(=O)(=O)O[*]
chebi_ontology
organosulfate oxoanions
CHEBI:58958
organosulfate oxoanion
organosulfate oxoanions
ChEBI
Any fatty acid whose skeletal carbon atoms form an unbranched open chain.
chebi_ontology
straight-chain fatty acids
CHEBI:59202
straight-chain fatty acid
straight-chain fatty acids
ChEBI
A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid.
chebi_ontology
straight-chain FA anion
straight-chain FA anions
straight-chain fatty acid anions
CHEBI:59203
straight-chain fatty acid anion
straight-chain FA anion
ChEBI
straight-chain FA anions
ChEBI
straight-chain fatty acid anions
ChEBI
Compounds containing one or more phosphoric acid units.
chebi_ontology
CHEBI:59698
phosphoric acids
A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
chebi_ontology
nucleophile
nucleophiles
nucleophilic reagents
CHEBI:59740
nucleophilic reagent
nucleophile
ChEBI
nucleophiles
ChEBI
nucleophilic reagents
ChEBI
Hydroxy boron compounds of general formula BxOyHz.
chebi_ontology
CHEBI:59765
boric acids
Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group.
-1
C2H3NO2R
88.08520
73.01638
C[C@H](N)C([O-])=O
chebi_ontology
L-alpha-amino carboxylate
CHEBI:59814
L-alpha-amino acid anion
L-alpha-amino carboxylate
ChEBI
Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group.
0
C2H4NO2R
74.059
74.02420
[NH3+][C@@H]([*])C([O-])=O
chebi_ontology
L-alpha-amino acid zwitterions
an L-alpha-amino acid
CHEBI:59869
L-alpha-amino acid zwitterion
L-alpha-amino acid zwitterions
ChEBI
an L-alpha-amino acid
UniProt
Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group.
0
C2H4NO2R
74.059
74.02420
[NH3+][C@H]([*])C([O-])=O
chebi_ontology
D-alpha-amino acid zwitterions
a D-alpha-amino acid
CHEBI:59871
D-alpha-amino acid zwitterion
D-alpha-amino acid zwitterions
ChEBI
a D-alpha-amino acid
UniProt
A carboxylic acid anion that is the conjugate base of an N-acyl-L-alpha-amino acid arising from deprotonation of the C-1 carboxy group.
-1
C3H2NO3R2
100.05290
100.00347
[O-]C(=O)[C@H]([*])NC([*])=O
chebi_ontology
N-acyl-L-alpha-amino acid(1-)
an N-acyl-L-amino acid
CHEBI:59874
N-acyl-L-alpha-amino acid anion
N-acyl-L-alpha-amino acid(1-)
ChEBI
an N-acyl-L-amino acid
UniProt
The conjugate base of an N-acyl-D-alpha-amino acid arising from deprotonation of the C-1 carboxy group.
-1
C3H2NO3R2
100.05290
100.00347
[O-]C(=O)[C@@H]([*])NC([*])=O
chebi_ontology
N-acyl-D-alpha-amino acid(1-)
an N-acyl-D-amino acid
CHEBI:59876
N-acyl-D-alpha-amino acid anion
N-acyl-D-alpha-amino acid(1-)
ChEBI
an N-acyl-D-amino acid
UniProt
Any anion arising from deprotonation of at least one OH group in a flavonoid compound.
chebi_ontology
flavonoid oxoanions
CHEBI:60038
flavonoid oxoanion
flavonoid oxoanions
ChEBI
A metal cation with a valence of two.
chebi_ontology
a divalent metal cation
CHEBI:60240
divalent metal cation
a divalent metal cation
UniProt
An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one.
chebi_ontology
a monovalent cation
CHEBI:60242
monovalent inorganic cation
a monovalent cation
UniProt
R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives.
+1
CHN3R5
130.21130
55.01705
[H][N+](C)=C(N(C)C)N(C)C
chebi_ontology
diaminomethaniminium ion
diaminomethaniminium ions
guanidinium ions
CHEBI:60251
guanidinium ion
diaminomethaniminium ion
ChEBI
diaminomethaniminium ions
ChEBI
guanidinium ions
ChEBI
Zwitterionic form of any peptide where the amino terminus is positively charged and the carboxy terminus is negatively charged.
0
C2H4NO2R(C2H2NOR)n
chebi_ontology
peptide zwitterions
CHEBI:60466
peptide zwitterion
peptide zwitterions
ChEBI
Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.
chebi_ontology
adjuvants
CHEBI:60809
adjuvant
adjuvants
ChEBI
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
chebi_ontology
tubulin modulators
CHEBI:60832
tubulin modulator
tubulin modulators
ChEBI
Any alpha-amino acid anion in which the parent amino acid has D-configuration.
-1
C2H3NO2R
88.08520
73.01638
C[C@@H](N)C([O-])=O
chebi_ontology
D-alpha-amino acid anions
D-alpha-amino carboxylate
CHEBI:60895
D-alpha-amino acid anion
D-alpha-amino acid anions
ChEBI
D-alpha-amino carboxylate
ChEBI
A poison that interferes with the function of the kidneys.
chebi_ontology
nephrotoxins
CHEBI:61015
nephrotoxin
nephrotoxins
ChEBI
Any compound that has a nucleobase as a part.
chebi_ontology
nucleobase-containing compound
nucleobase-containing compounds
nucleobase-containing molecular entities
CHEBI:61120
nucleobase-containing molecular entity
nucleobase-containing compound
SUBMITTER
nucleobase-containing compounds
ChEBI
nucleobase-containing molecular entities
ChEBI
A flavonoid oxoanion that is the conjugate base of hesperetin arising from selective deprtotonation of the 7-hydroxy group.
-1
C16H13O6
InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/p-1/t14-/m0/s1
AIONOLUJZLIMTK-AWEZNQCLSA-M
301.27080
301.07176
COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc([O-])cc2O1
MetaCyc:CPD-7072
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxochroman-7-olate
chebi_ontology
hesperetin anion
CHEBI:61249
hesperetin(1-)
MetaCyc:CPD-7072
SUBMITTER
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxochroman-7-olate
IUPAC
hesperetin anion
ChEBI
chebi_ontology
CHEBI:616459
carbamimidoylazanium
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
PMID:17099073
chebi_ontology
microtubule destabilising agent
microtubule destabilising agents
microtubule destabilising role
microtubule destabilizing role
microtubule-destabilising agents
microtubule-destabilizing agent
microtubule-destabilizing agents
CHEBI:61951
microtubule-destabilising agent
PMID:17099073
Europe PMC
microtubule destabilising agent
ChEBI
microtubule destabilising agents
ChEBI
microtubule destabilising role
ChEBI
microtubule destabilizing role
SUBMITTER
microtubule-destabilising agents
ChEBI
microtubule-destabilizing agent
ChEBI
microtubule-destabilizing agents
ChEBI
Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group.
0
C2H4NO2R
74.059
74.02420
C(C([O-])=O)(*)[NH3+]
MetaCyc:Polar-amino-acids
chebi_ontology
a polar amino acid
CHEBI:62031
polar amino acid zwitterion
MetaCyc:Polar-amino-acids
SUBMITTER
a polar amino acid
UniProt
An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens.
-1
CH2O3SR
94.09000
93.97246
[H]C([H])([*])S([O-])(=O)=O
KEGG:C15521
MetaCyc:Alkanesulfonates
chebi_ontology
1,1-di-unsubstituted alkanesulfonate
1,1-di-unsubstituted alkanesulfonates
1,1-diunsubstituted alkanesulfonates
CHEBI:62081
1,1-diunsubstituted alkanesulfonate
1,1-di-unsubstituted alkanesulfonate
ChEBI
1,1-di-unsubstituted alkanesulfonates
ChEBI
1,1-diunsubstituted alkanesulfonates
ChEBI
The dicarboxylic acid dianion formed from folic acid by loss of a proton from each of the two carboxy groups in the glutamic acid moiety.
-2
C19H17N7O6
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/p-2/t12-/m0/s1
OVBPIULPVIDEAO-LBPRGKRZSA-L
439.38160
439.12513
Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)nc2c(=O)[nH]1
MetaCyc:CPD-12826
N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate(2-)
chebi_ontology
folate
CHEBI:62501
folate(2-)
MetaCyc:CPD-12826
SUBMITTER
N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate(2-)
IUPAC
folate
UniProt
Any additive that enhances the efficiency of fuel.
chebi_ontology
fuel additives
fuel enhancer
CHEBI:62803
fuel additive
fuel additives
ChEBI
fuel enhancer
ChEBI
A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity.
chebi_ontology
glycosyl compounds
CHEBI:63161
glycosyl compound
glycosyl compounds
ChEBI
Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.
chebi_ontology
carbohydrate derivatives
derivatised carbohydrate
derivatised carbohydrates
derivatized carbohydrate
derivatized carbohydrates
CHEBI:63299
carbohydrate derivative
carbohydrate derivatives
ChEBI
derivatised carbohydrate
ChEBI
derivatised carbohydrates
ChEBI
derivatized carbohydrate
ChEBI
derivatized carbohydrates
ChEBI
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1).
Wikipedia:Alkaline_phosphatase
chebi_ontology
EC 3.1.3.1 (alkaline phosphatase) inhibitors
EC 3.1.3.1 inhibitor
EC 3.1.3.1 inhibitors
alkaline phenyl phosphatase inhibitor
alkaline phenyl phosphatase inhibitors
alkaline phosphatase (EC 3.1.3.1) inhibitor
alkaline phosphatase (EC 3.1.3.1) inhibitors
alkaline phosphatase inhibitor
alkaline phosphatase inhibitors
alkaline phosphohydrolase inhibitor
alkaline phosphohydrolase inhibitors
alkaline phosphomonoesterase inhibitor
alkaline phosphomonoesterase inhibitors
glycerophosphatase inhibitor
glycerophosphatase inhibitors
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors
phosphomonoesterase inhibitor
phosphomonoesterase inhibitors
CHEBI:63332
EC 3.1.3.1 (alkaline phosphatase) inhibitor
EC 3.1.3.1 (alkaline phosphatase) inhibitors
ChEBI
EC 3.1.3.1 inhibitor
ChEBI
EC 3.1.3.1 inhibitors
ChEBI
alkaline phenyl phosphatase inhibitor
ChEBI
alkaline phenyl phosphatase inhibitors
ChEBI
alkaline phosphatase (EC 3.1.3.1) inhibitor
ChEBI
alkaline phosphatase (EC 3.1.3.1) inhibitors
ChEBI
alkaline phosphatase inhibitor
ChEBI
alkaline phosphatase inhibitors
ChEBI
alkaline phosphohydrolase inhibitor
ChEBI
alkaline phosphohydrolase inhibitors
ChEBI
alkaline phosphomonoesterase inhibitor
ChEBI
alkaline phosphomonoesterase inhibitors
ChEBI
glycerophosphatase inhibitor
ChEBI
glycerophosphatase inhibitors
ChEBI
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor
ChEBI
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors
ChEBI
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor
ChEBI
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors
ChEBI
phosphomonoesterase inhibitor
ChEBI
phosphomonoesterase inhibitors
ChEBI
A carbohydrate derivative that is formally obtained from a disaccharide.
chebi_ontology
disaccharide derivatives
CHEBI:63353
disaccharide derivative
disaccharide derivatives
ChEBI
A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated).
chebi_ontology
sulfur-containing amino-acid anions
CHEBI:63470
sulfur-containing amino-acid anion
sulfur-containing amino-acid anions
ChEBI
An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated).
chebi_ontology
aromatic amino-acid anions
CHEBI:63473
aromatic amino-acid anion
aromatic amino-acid anions
ChEBI
A substance capable of undergoing rapid and highly exothermic decomposition.
Wikipedia:Explosive_material
chebi_ontology
explosive compound
explosive compounds
explosive material
explosives
explosives chemical
explosives chemicals
CHEBI:63490
explosive
explosive compound
ChEBI
explosive compounds
ChEBI
explosive material
ChEBI
explosives
ChEBI
explosives chemical
ChEBI
explosives chemicals
ChEBI
Any substance which is added to food to preserve or enhance its flavour and/or appearance.
Wikipedia:Food_additive
chebi_ontology
food additives
CHEBI:64047
food additive
food additives
ChEBI
Any organic salt prepared using an organosulfonic acid as the acid component.
chebi_ontology
organosulfonate salts
organosulphonate salt
organosulphonate salts
CHEBI:64382
organosulfonate salt
organosulfonate salts
ChEBI
organosulphonate salt
ChEBI
organosulphonate salts
ChEBI
A food additive which is added to flour or dough to improve baking quality and/or colour.
Wikipedia:Flour_treatment_agent
flour treatment agent
chebi_ontology
dough improver
dough improvers
improving agent
improving agents
CHEBI:64577
flour treatment agent
flour treatment agent
ChEBI
dough improver
ChEBI
dough improvers
ChEBI
improving agent
ChEBI
improving agents
ChEBI
An inorganic cation with a valency of two.
chebi_ontology
CHEBI:64641
divalent inorganic cation
An organic molecular entity containing a single carbon atom (C1).
chebi_ontology
one-carbon compounds
CHEBI:64708
one-carbon compound
one-carbon compounds
ChEBI
Any organic molecular entity that is acidic and contains carbon in covalent linkage.
chebi_ontology
organic acids
CHEBI:64709
organic acid
organic acids
ChEBI
The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it.
Wikipedia:Cosmetics
chebi_ontology
cosmetic component
cosmetics
CHEBI:64857
cosmetic
cosmetic component
ChEBI
cosmetics
ChEBI
Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
Wikipedia:Poison
chebi_ontology
poisonous agent
poisonous agents
poisonous substance
poisonous substances
poisons
toxic agent
toxic agents
toxic substance
toxic substances
CHEBI:64909
poison
poisonous agent
ChEBI
poisonous agents
ChEBI
poisonous substance
ChEBI
poisonous substances
ChEBI
poisons
ChEBI
toxic agent
ChEBI
toxic agents
ChEBI
toxic substance
ChEBI
toxic substances
ChEBI
Any compound that inhibits cell division (mitosis).
Wikipedia:Mitotic_inhibitor
chebi_ontology
antimitotics
mitosis inhibitor
mitosis inhibitors
mitotic inhibitor
mitotic inhibitors
CHEBI:64911
antimitotic
antimitotics
ChEBI
mitosis inhibitor
ChEBI
mitosis inhibitors
ChEBI
mitotic inhibitor
ChEBI
mitotic inhibitors
ChEBI
An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
chebi_ontology
antiplasmodial agent
antiplasmodial agents
antiplasmodial drugs
antiplasmodium agent
antiplasmodium agents
antiplasmodium drug
antiplasmodium drugs
CHEBI:64915
antiplasmodial drug
antiplasmodial agent
ChEBI
antiplasmodial agents
ChEBI
antiplasmodial drugs
ChEBI
antiplasmodium agent
ChEBI
antiplasmodium agents
ChEBI
antiplasmodium drug
ChEBI
antiplasmodium drugs
ChEBI
An N-acyl-L-alpha-amino acid anion obtained by deprotonation of any folic acid.
chebi_ontology
folate
folate anion
folate anions
CHEBI:67011
folates
folate
ChEBI
folate anion
ChEBI
folate anions
ChEBI
A chemosterilant intended to sterilize insects.
chebi_ontology
insect chemosterilant
insect chemosterilants
insect sterilants
CHEBI:67105
insect sterilant
insect chemosterilant
ChEBI
insect chemosterilants
ChEBI
insect sterilants
ChEBI
A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups.
0
C8H18O6S2
InChI=1S/C8H18O6S2/c1-7(13-15(3,9)10)5-6-8(2)14-16(4,11)12/h7-8H,5-6H2,1-4H3
JDZNTUQRMDAIRO-UHFFFAOYSA-N
274.35500
274.05448
CC(CCC(C)OS(C)(=O)=O)OS(C)(=O)=O
CAS:55-93-6
PMID:3800321
Reaxys:1796040
hexane-2,5-diyl dimethanesulfonate
FlyBase miscellaneous CV
chebi_ontology
1,4-bis(methylsulfonyloxy)-1,4-dimethylbutane
1,4-dimethanesulfonoxy-1,4-dimethylbutane
1,4-dimethylbusulfan
1,4-dimethylmyleran
2,5-dimethanesulfomyloxyhexane
2,5-hexanediol dimesylate
2,5-hexanediol dimethylsulfonate
DMM
dimethylbusulfan
CHEBI:67107
dimethylmyleran
CAS:55-93-6
ChemIDplus
PMID:3800321
Europe PMC
Reaxys:1796040
Reaxys
hexane-2,5-diyl dimethanesulfonate
IUPAC
1,4-bis(methylsulfonyloxy)-1,4-dimethylbutane
ChemIDplus
1,4-dimethanesulfonoxy-1,4-dimethylbutane
ChemIDplus
1,4-dimethylbusulfan
ChEBI
1,4-dimethylmyleran
ChEBI
2,5-dimethanesulfomyloxyhexane
ChemIDplus
2,5-hexanediol dimesylate
ChEBI
2,5-hexanediol dimethylsulfonate
ChemIDplus
DMM
ChemIDplus
dimethylbusulfan
ChemIDplus
A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
PMID:8597061
Wikipedia:Ryanodine_receptor
chebi_ontology
RyR activator
RyR activators
RyR agonist
RyR agonists
RyRs activator
RyRs agonist
ryanodine receptor activator
ryanodine receptor activators
CHEBI:67114
ryanodine receptor agonist
PMID:8597061
Europe PMC
RyR activator
ChEBI
RyR activators
ChEBI
RyR agonist
ChEBI
RyR agonists
ChEBI
RyRs activator
ChEBI
RyRs agonist
ChEBI
ryanodine receptor activator
ChEBI
ryanodine receptor activators
ChEBI
An ammonium ion resulting from the protonation of the tertiary amino group of lycanthone.
+1
C20H25N2O2S
InChI=1S/C20H24N2O2S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20/h5-10,21,23H,3-4,11-13H2,1-2H3/p+1
MFZWMTSUNYWVBU-UHFFFAOYSA-O
357.49000
357.16313
CC[NH+](CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12
Reaxys:19574704
N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium
chebi_ontology
CHEBI:67141
hycanthone(1+)
Reaxys:19574704
Reaxys
N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium
IUPAC
A molecule that can substitute for a normal nucleobase in nucleic acids.
Wikipedia:Base_analog
FlyBase miscellaneous CV
chebi_ontology
base analog
base analogs
base analogue
base analogues
nucleobase analog
nucleobase analogs
nucleobase analogues
CHEBI:67142
nucleobase analogue
base analog
ChEBI
base analogs
ChEBI
base analogue
ChEBI
base analogues
ChEBI
nucleobase analog
ChEBI
nucleobase analogs
ChEBI
nucleobase analogues
ChEBI
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
chebi_ontology
Type I cell-death inhibitor
Type I cell-death inhibitors
Type I programmed cell-death inhibitor
Type I programmed cell-death inhibitors
apoptosis inhibitors
CHEBI:68494
apoptosis inhibitor
Type I cell-death inhibitor
ChEBI
Type I cell-death inhibitors
ChEBI
Type I programmed cell-death inhibitor
ChEBI
Type I programmed cell-death inhibitors
ChEBI
apoptosis inhibitors
ChEBI
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
chebi_ontology
Type I cell-death inducer
Type I cell-death inducers
Type I programmed cell-death inducer
Type I programmed cell-death inducers
apoptosis inducers
CHEBI:68495
apoptosis inducer
Type I cell-death inducer
ChEBI
Type I cell-death inducers
ChEBI
Type I programmed cell-death inducer
ChEBI
Type I programmed cell-death inducers
ChEBI
apoptosis inducers
ChEBI
An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
Wikipedia:Topoisomerase
chebi_ontology
topoisomerase inhibitors
CHEBI:70727
topoisomerase inhibitor
topoisomerase inhibitors
ChEBI
An antagonist at any adenosine receptor.
Wikipedia:Adenosine_receptor
chebi_ontology
adenosine receptor antagonists
CHEBI:71232
adenosine receptor antagonist
adenosine receptor antagonists
ChEBI
An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)
Wikipedia:Transferase
chebi_ontology
EC 2 inhibitor
EC 2 inhibitors
EC 2.* (transferase) inhibitors
EC 2.* inhibitor
EC 2.* inhibitors
transferase inhibitor
transferase inhibitors
CHEBI:71300
EC 2.* (transferase) inhibitor
EC 2 inhibitor
ChEBI
EC 2 inhibitors
ChEBI
EC 2.* (transferase) inhibitors
ChEBI
EC 2.* inhibitor
ChEBI
EC 2.* inhibitors
ChEBI
transferase inhibitor
ChEBI
transferase inhibitors
ChEBI
Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them.
Wikipedia:Flavonoids
chebi_ontology
flavonoid
CHEBI:72544
flavonoids
flavonoid
ChEBI
Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
chebi_ontology
organic compound
organic compounds
organic molecules
CHEBI:72695
organic molecule
organic compound
ChEBI
organic compounds
ChEBI
organic molecules
ChEBI
A member of the class of flavanones having one or more glycosyl residues attached at unspecified positions.
chebi_ontology
flavanone glycosides
CHEBI:72730
flavanone glycoside
flavanone glycosides
ChEBI
An L-alpha-amino acid which is biosynthesised from erythrose 4-phosphate and phosphoenolpyruvate (i.e. phenylalanine, tyrosine, and tryptophan). A closed class.
chebi_ontology
erythrose 4-phosphate and phosphoenolpyruvate family amino acid
erythrose 4-phosphate and phosphoenolpyruvate family amino acids
erythrose 4-phosphate family amino acid
erythrose 4-phosphate family amino acids
erythrose 4-phosphate/phosphoenolpyruvate family amino acids
phosphoenolpyruvate family amino acid
phosphoenolpyruvate family amino acids
CHEBI:73690
erythrose 4-phosphate/phosphoenolpyruvate family amino acid
erythrose 4-phosphate and phosphoenolpyruvate family amino acid
ChEBI
erythrose 4-phosphate and phosphoenolpyruvate family amino acids
ChEBI
erythrose 4-phosphate family amino acid
ChEBI
erythrose 4-phosphate family amino acids
ChEBI
erythrose 4-phosphate/phosphoenolpyruvate family amino acids
ChEBI
phosphoenolpyruvate family amino acid
ChEBI
phosphoenolpyruvate family amino acids
ChEBI
An antimetabolite that impairs the action of folic acids
Wikipedia:Antifolate
chebi_ontology
antifolates
folic acid antagonist
folic acid antagonists
CHEBI:73913
antifolate
antifolates
ChEBI
folic acid antagonist
ChEBI
folic acid antagonists
ChEBI
A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.
Wikipedia:Astringent
chebi_ontology
adstringent
adstringents
astringents
CHEBI:74783
astringent
adstringent
ChEBI
adstringents
ChEBI
astringents
ChEBI
An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*).
chebi_ontology
EC 5.* (isomerase) inhibitors
EC 5.* inhibitor
EC 5.* inhibitors
EC 5.*.*.* inhibitor
EC 5.*.*.* inhibitors
isomerase (EC 5.*) inhibitor
isomerase (EC 5.*) inhibitors
isomerase inhibitor
isomerase inhibitors
CHEBI:75596
EC 5.* (isomerase) inhibitor
EC 5.* (isomerase) inhibitors
ChEBI
EC 5.* inhibitor
ChEBI
EC 5.* inhibitors
ChEBI
EC 5.*.*.* inhibitor
ChEBI
EC 5.*.*.* inhibitors
ChEBI
isomerase (EC 5.*) inhibitor
ChEBI
isomerase (EC 5.*) inhibitors
ChEBI
isomerase inhibitor
ChEBI
isomerase inhibitors
ChEBI
A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).
chebi_ontology
C--N bond-forming ligase inhibitor
C--N bond-forming ligase inhibitors
C-N bond-forming ligase (EC 6.3.*) inhibitor
C-N bond-forming ligase (EC 6.3.*) inhibitors
C-N bond-forming ligase inhibitor
C-N bond-forming ligase inhibitors
EC 6.3.* (C-N bond-forming ligase) inhibitorS
EC 6.3.* inhibitor
EC 6.3.* inhibitors
EC 6.3.*.* inhibitor
EC 6.3.*.* inhibitors
CHEBI:75600
EC 6.3.* (C-N bond-forming ligase) inhibitor
C--N bond-forming ligase inhibitor
ChEBI
C--N bond-forming ligase inhibitors
ChEBI
C-N bond-forming ligase (EC 6.3.*) inhibitor
ChEBI
C-N bond-forming ligase (EC 6.3.*) inhibitors
ChEBI
C-N bond-forming ligase inhibitor
ChEBI
C-N bond-forming ligase inhibitors
ChEBI
EC 6.3.* (C-N bond-forming ligase) inhibitorS
ChEBI
EC 6.3.* inhibitor
ChEBI
EC 6.3.* inhibitors
ChEBI
EC 6.3.*.* inhibitor
ChEBI
EC 6.3.*.* inhibitors
ChEBI
Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
Wikipedia:Ligase
chebi_ontology
EC 6.* (ligase) inhibitors
EC 6.* inhibitor
EC 6.* inhibitors
EC 6.*.*.* inhibitor
EC 6.*.*.* inhibitors
ligase inhibitor
ligase inhibitors
CHEBI:75603
EC 6.* (ligase) inhibitor
EC 6.* (ligase) inhibitors
ChEBI
EC 6.* inhibitor
ChEBI
EC 6.* inhibitors
ChEBI
EC 6.*.*.* inhibitor
ChEBI
EC 6.*.*.* inhibitors
ChEBI
ligase inhibitor
ChEBI
ligase inhibitors
ChEBI
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
chebi_ontology
eukaryotic metabolites
CHEBI:75763
eukaryotic metabolite
eukaryotic metabolites
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
CHEBI:77721
CHEBI:77743
chebi_ontology
animal metabolites
CHEBI:75767
animal metabolite
animal metabolites
ChEBI
Any animal metabolite produced during a metabolic reaction in mammals.
CHEBI:77464
CHEBI:77744
chebi_ontology
mammalian metabolites
CHEBI:75768
mammalian metabolite
mammalian metabolites
ChEBI
Any of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises vitamin B1, B2, B3, B5, B6, B7, B9, and B12. (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such.)
PMID:22743781
PMID:23093174
PMID:23238962
PMID:23449527
PMID:23462586
PMID:23690582
Wikipedia:B_vitamin
chebi_ontology
B vitamins
B-group vitamin
B-group vitamins
vitamin B
CHEBI:75769
B vitamin
PMID:22743781
Europe PMC
PMID:23093174
Europe PMC
PMID:23238962
Europe PMC
PMID:23449527
Europe PMC
PMID:23462586
Europe PMC
PMID:23690582
Europe PMC
B vitamins
ChEBI
B-group vitamin
ChEBI
B-group vitamins
ChEBI
vitamin B
ChEBI
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
chebi_ontology
Mus musculus metabolite
Mus musculus metabolites
mouse metabolites
CHEBI:75771
mouse metabolite
Mus musculus metabolite
ChEBI
Mus musculus metabolites
ChEBI
mouse metabolites
ChEBI
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
CHEBI:76949
CHEBI:76951
chebi_ontology
S. cerevisiae metabolite
S. cerevisiae metabolites
S. cerevisiae secondary metabolite
S. cerevisiae secondary metabolites
Saccharomyces cerevisiae metabolites
Saccharomyces cerevisiae secondary metabolites
baker's yeast metabolite
baker's yeast metabolites
baker's yeast secondary metabolite
baker's yeast secondary metabolites
CHEBI:75772
Saccharomyces cerevisiae metabolite
S. cerevisiae metabolite
ChEBI
S. cerevisiae metabolites
ChEBI
S. cerevisiae secondary metabolite
ChEBI
S. cerevisiae secondary metabolites
ChEBI
Saccharomyces cerevisiae metabolites
ChEBI
Saccharomyces cerevisiae secondary metabolites
ChEBI
baker's yeast metabolite
ChEBI
baker's yeast metabolites
ChEBI
baker's yeast secondary metabolite
ChEBI
baker's yeast secondary metabolites
ChEBI
Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
chebi_ontology
prokaryotic metabolites
CHEBI:75787
prokaryotic metabolite
prokaryotic metabolites
ChEBI
An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid.
0
C2H4NO2R
74.059
74.02420
[NH3+]C([*])C([O-])=O
MetaCyc:Aromatic-Amino-Acids
chebi_ontology
an aromatic amino-acid
aromatic amino-acid zwitterions
CHEBI:76042
aromatic amino-acid zwitterion
MetaCyc:Aromatic-Amino-Acids
SUBMITTER
an aromatic amino-acid
UniProt
aromatic amino-acid zwitterions
ChEBI
Any metabolite produced by metabolism of a xenobiotic compound.
chebi_ontology
xenobiotic metabolites
CHEBI:76206
xenobiotic metabolite
xenobiotic metabolites
ChEBI
A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans.
PMID:22519407
PMID:24001847
chebi_ontology
propellants
CHEBI:76414
propellant
PMID:22519407
Europe PMC
PMID:24001847
Europe PMC
propellants
ChEBI
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
CHEBI:77078
chebi_ontology
marine metabolites
CHEBI:76507
marine metabolite
marine metabolites
ChEBI
A nitroso compound that is any urea in which one of the nitrogens is substituted by a nitroso group
chebi_ontology
CHEBI:76551
N-nitrosoureas
A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*).
chebi_ontology
EC 2.7.* (P-containing group transferase) inhibitors
EC 2.7.* (phosphorus-containing group transferase) inhibitor
EC 2.7.* (phosphorus-containing group transferase) inhibitors
EC 2.7.* inhibitor
EC 2.7.* inhibitors
phosphorus-containing group transferase (EC 2.7.*) inhibitor
phosphorus-containing group transferase (EC 2.7.*) inhibitors
phosphorus-containing group transferase inhibitor
phosphorus-containing group transferase inhibitors
CHEBI:76668
EC 2.7.* (P-containing group transferase) inhibitor
EC 2.7.* (P-containing group transferase) inhibitors
ChEBI
EC 2.7.* (phosphorus-containing group transferase) inhibitor
ChEBI
EC 2.7.* (phosphorus-containing group transferase) inhibitors
ChEBI
EC 2.7.* inhibitor
ChEBI
EC 2.7.* inhibitors
ChEBI
phosphorus-containing group transferase (EC 2.7.*) inhibitor
ChEBI
phosphorus-containing group transferase (EC 2.7.*) inhibitors
ChEBI
phosphorus-containing group transferase inhibitor
ChEBI
phosphorus-containing group transferase inhibitors
ChEBI
An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*).
chebi_ontology
EC 5.99.* (miscellaneous isomerases) inhibitor
EC 5.99.* (miscellaneous isomerases) inhibitors
EC 5.99.* (other isomerase) inhibitor
EC 5.99.* (other isomerase) inhibitors
EC 5.99.* (other isomerases) inhibitors
EC 5.99.* inhibitor
EC 5.99.* inhibitors
CHEBI:76697
EC 5.99.* (other isomerases) inhibitor
EC 5.99.* (miscellaneous isomerases) inhibitor
ChEBI
EC 5.99.* (miscellaneous isomerases) inhibitors
ChEBI
EC 5.99.* (other isomerase) inhibitor
ChEBI
EC 5.99.* (other isomerase) inhibitors
ChEBI
EC 5.99.* (other isomerases) inhibitors
ChEBI
EC 5.99.* inhibitor
ChEBI
EC 5.99.* inhibitors
ChEBI
An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
Wikipedia:Oxidoreductase
chebi_ontology
EC 1.* (oxidoreductase) inhibitors
EC 1.* inhibitor
EC 1.* inhibitors
oxidoreductase (EC 1.*) inhibitor
oxidoreductase (EC 1.*) inhibitors
oxidoreductase inhibitor
oxidoreductase inhibitors
CHEBI:76725
EC 1.* (oxidoreductase) inhibitor
EC 1.* (oxidoreductase) inhibitors
ChEBI
EC 1.* inhibitor
ChEBI
EC 1.* inhibitors
ChEBI
oxidoreductase (EC 1.*) inhibitor
ChEBI
oxidoreductase (EC 1.*) inhibitors
ChEBI
oxidoreductase inhibitor
ChEBI
oxidoreductase inhibitors
ChEBI
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*).
chebi_ontology
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors
EC 1.5.* inhibitor
EC 1.5.* inhibitors
inhibitor of oxidoreductase acting on CH-NH group of donor
inhibitor of oxidoreductase acting on CH-NH group of donors
inhibitors of oxidoreductase acting on CH-NH group of donor
inhibitors of oxidoreductase acting on CH-NH group of donors
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors
CHEBI:76731
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors
ChEBI
EC 1.5.* inhibitor
ChEBI
EC 1.5.* inhibitors
ChEBI
inhibitor of oxidoreductase acting on CH-NH group of donor
ChEBI
inhibitor of oxidoreductase acting on CH-NH group of donors
ChEBI
inhibitors of oxidoreductase acting on CH-NH group of donor
ChEBI
inhibitors of oxidoreductase acting on CH-NH group of donors
ChEBI
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor
ChEBI
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors
ChEBI
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors).
chebi_ontology
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors
EC 1.8.* inhibitor
EC 1.8.* inhibitors
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors
CHEBI:76735
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors
ChEBI
EC 1.8.* inhibitor
ChEBI
EC 1.8.* inhibitors
ChEBI
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor
ChEBI
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors
ChEBI
Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
Wikipedia:Hydrolase
chebi_ontology
EC 3.* (hydrolase) inhibitors
EC 3.* inhibitor
EC 3.* inhibitors
EC 3.*.*.* inhibitor
EC 3.*.*.* inhibitors
hydrolase (EC 3.*) inhibitor
hydrolase (EC 3.*) inhibitors
hydrolase inhibitor
hydrolase inhibitors
CHEBI:76759
EC 3.* (hydrolase) inhibitor
EC 3.* (hydrolase) inhibitors
ChEBI
EC 3.* inhibitor
ChEBI
EC 3.* inhibitors
ChEBI
EC 3.*.*.* inhibitor
ChEBI
EC 3.*.*.* inhibitors
ChEBI
hydrolase (EC 3.*) inhibitor
ChEBI
hydrolase (EC 3.*) inhibitors
ChEBI
hydrolase inhibitor
ChEBI
hydrolase inhibitors
ChEBI
A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*).
chebi_ontology
EC 3.1.* (ester hydrolase) inhibitors
EC 3.1.* inhibitor
EC 3.1.* inhibitors
ester hydrolase (EC 3.1.*) inhibitor
ester hydrolase (EC 3.1.*) inhibitors
ester hydrolase inhibitor
ester hydrolase inhibitors
CHEBI:76760
EC 3.1.* (ester hydrolase) inhibitor
EC 3.1.* (ester hydrolase) inhibitors
ChEBI
EC 3.1.* inhibitor
ChEBI
EC 3.1.* inhibitors
ChEBI
ester hydrolase (EC 3.1.*) inhibitor
ChEBI
ester hydrolase (EC 3.1.*) inhibitors
ChEBI
ester hydrolase inhibitor
ChEBI
ester hydrolase inhibitors
ChEBI
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
chebi_ontology
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
EC 3.5.* inhibitor
EC 3.5.* inhibitors
CHEBI:76764
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
ChEBI
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
ChEBI
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
ChEBI
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
ChEBI
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
ChEBI
EC 3.5.* inhibitor
ChEBI
EC 3.5.* inhibitors
ChEBI
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*).
chebi_ontology
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors
EC 3.1.3.* inhibitor
EC 3.1.3.* inhibitors
inhibitor of phosphoric monoester hydrolase
inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)
inhibitors of phosphoric monoester hydrolase
inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors
phosphoric monoester hydrolase inhibitor
phosphoric monoester hydrolase inhibitors
CHEBI:76775
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors
ChEBI
EC 3.1.3.* inhibitor
ChEBI
EC 3.1.3.* inhibitors
ChEBI
inhibitor of phosphoric monoester hydrolase
ChEBI
inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)
ChEBI
inhibitors of phosphoric monoester hydrolase
ChEBI
inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)
ChEBI
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor
ChEBI
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors
ChEBI
phosphoric monoester hydrolase inhibitor
ChEBI
phosphoric monoester hydrolase inhibitors
ChEBI
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
chebi_ontology
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
EC 3.5.1.* inhibitor
EC 3.5.1.* inhibitors
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
CHEBI:76807
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
ChEBI
EC 3.5.1.* inhibitor
ChEBI
EC 3.5.1.* inhibitors
ChEBI
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
ChEBI
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
ChEBI
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*).
chebi_ontology
EC 2.7.11.* (protein-serine/threonine kinase) inhibitors
EC 2.7.11.* inhibitor
EC 2.7.11.* inhibitors
protein-serine/threonine kinase (EC 2.7.11.*) inhibitor
protein-serine/threonine kinase (EC 2.7.11.*) inhibitors
protein-serine/threonine kinase inhibitor
protein-serine/threonine kinase inhibitors
CHEBI:76812
EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
EC 2.7.11.* (protein-serine/threonine kinase) inhibitors
ChEBI
EC 2.7.11.* inhibitor
ChEBI
EC 2.7.11.* inhibitors
ChEBI
protein-serine/threonine kinase (EC 2.7.11.*) inhibitor
ChEBI
protein-serine/threonine kinase (EC 2.7.11.*) inhibitors
ChEBI
protein-serine/threonine kinase inhibitor
ChEBI
protein-serine/threonine kinase inhibitors
ChEBI
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).
chebi_ontology
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors
EC 6.3.1.* inhibitor
EC 6.3.1.* inhibitors
acid-ammonia (or amine) ligase inhibitor
acid-ammonia (or amine) ligase inhibitors
CHEBI:76823
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors
ChEBI
EC 6.3.1.* inhibitor
ChEBI
EC 6.3.1.* inhibitors
ChEBI
acid-ammonia (or amine) ligase inhibitor
ChEBI
acid-ammonia (or amine) ligase inhibitors
ChEBI
An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class.
chebi_ontology
EC 5.99.1.* (miscellaneous isomerase) inhibitors
EC 5.99.1.* inhibitor
EC 5.99.1.* inhibitors
CHEBI:76830
EC 5.99.1.* (miscellaneous isomerase) inhibitor
EC 5.99.1.* (miscellaneous isomerase) inhibitors
ChEBI
EC 5.99.1.* inhibitor
ChEBI
EC 5.99.1.* inhibitors
ChEBI
An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*).
chebi_ontology
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.5.1.* inhibitor
EC 1.5.1.* inhibitors
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors
CHEBI:76863
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors
ChEBI
EC 1.5.1.* inhibitor
ChEBI
EC 1.5.1.* inhibitors
ChEBI
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor
ChEBI
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors
ChEBI
An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*).
chebi_ontology
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.8.1.* inhibitor
EC 1.8.1.* inhibitors
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors
CHEBI:76869
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors
ChEBI
EC 1.8.1.* inhibitor
ChEBI
EC 1.8.1.* inhibitors
ChEBI
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor
ChEBI
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
CHEBI:75766
CHEBI:76925
chebi_ontology
plant metabolites
plant secondary metabolites
CHEBI:76924
plant metabolite
plant metabolites
ChEBI
plant secondary metabolites
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
CHEBI:75765
CHEBI:76947
chebi_ontology
fungal metabolites
CHEBI:76946
fungal metabolite
fungal metabolites
ChEBI
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
chebi_ontology
human xenobiotic metabolites
CHEBI:76967
human xenobiotic metabolite
human xenobiotic metabolites
ChEBI
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
CHEBI:75760
CHEBI:76970
chebi_ontology
CHEBI:76969
bacterial metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
chebi_ontology
E.coli metabolite
E.coli metabolites
Escherichia coli metabolites
CHEBI:76971
Escherichia coli metabolite
E.coli metabolite
ChEBI
E.coli metabolites
ChEBI
Escherichia coli metabolites
ChEBI
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
Wikipedia:Trypanothione-disulfide_reductase
chebi_ontology
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors
EC 1.8.1.12 inhibitor
EC 1.8.1.12 inhibitors
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors
NADPH2:trypanothione oxidoreductase inhibitor
NADPH2:trypanothione oxidoreductase inhibitors
NADPH:trypanothione oxidoreductase inhibitor
NADPH:trypanothione oxidoreductase inhibitors
trypanothione reductase inhibitor
trypanothione reductase inhibitors
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors
trypanothione:NADP(+) oxidoreductase inhibitor
trypanothione:NADP(+) oxidoreductase inhibitors
CHEBI:77402
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors
ChEBI
EC 1.8.1.12 inhibitor
ChEBI
EC 1.8.1.12 inhibitors
ChEBI
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor
ChEBI
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors
ChEBI
NADPH2:trypanothione oxidoreductase inhibitor
ChEBI
NADPH2:trypanothione oxidoreductase inhibitors
ChEBI
NADPH:trypanothione oxidoreductase inhibitor
ChEBI
NADPH:trypanothione oxidoreductase inhibitors
ChEBI
trypanothione reductase inhibitor
ChEBI
trypanothione reductase inhibitors
ChEBI
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor
ChEBI
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors
ChEBI
trypanothione:NADP(+) oxidoreductase inhibitor
ChEBI
trypanothione:NADP(+) oxidoreductase inhibitors
ChEBI
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
CHEBI:75770
CHEBI:77123
chebi_ontology
H. sapiens metabolite
H. sapiens metabolites
Homo sapiens metabolite
Homo sapiens metabolites
CHEBI:77746
human metabolite
H. sapiens metabolite
ChEBI
H. sapiens metabolites
ChEBI
Homo sapiens metabolite
ChEBI
Homo sapiens metabolites
ChEBI
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
Wikipedia:Amidase
chebi_ontology
EC 3.5.1.4 (amidase) inhibitors
EC 3.5.1.4 inhibitor
EC 3.5.1.4 inhibitors
N-acetylaminohydrolase inhibitor
N-acetylaminohydrolase inhibitors
acylamidase inhibitor
acylamidase inhibitors
acylamide amidohydrolase inhibitor
acylamide amidohydrolase inhibitors
amidase (EC 3.5.1.4) inhibitor
amidase (EC 3.5.1.4) inhibitors
amidase inhibitor
amidase inhibitors
amidohydrolase inhibitor
amidohydrolase inhibitors
deaminase inhibitor
deaminase inhibitors
fatty acylamidase inhibitor
fatty acylamidase inhibitors
CHEBI:77941
EC 3.5.1.4 (amidase) inhibitor
EC 3.5.1.4 (amidase) inhibitors
ChEBI
EC 3.5.1.4 inhibitor
ChEBI
EC 3.5.1.4 inhibitors
ChEBI
N-acetylaminohydrolase inhibitor
ChEBI
N-acetylaminohydrolase inhibitors
ChEBI
acylamidase inhibitor
ChEBI
acylamidase inhibitors
ChEBI
acylamide amidohydrolase inhibitor
ChEBI
acylamide amidohydrolase inhibitors
ChEBI
amidase (EC 3.5.1.4) inhibitor
ChEBI
amidase (EC 3.5.1.4) inhibitors
ChEBI
amidase inhibitor
ChEBI
amidase inhibitors
ChEBI
amidohydrolase inhibitor
ChEBI
amidohydrolase inhibitors
ChEBI
deaminase inhibitor
ChEBI
deaminase inhibitors
ChEBI
fatty acylamidase inhibitor
ChEBI
fatty acylamidase inhibitors
ChEBI
A propellant that is used to expel foods from an aerosol container.
chebi_ontology
food propellants
CHEBI:78017
food propellant
food propellants
ChEBI
Any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
chebi_ontology
dietary component
dietary components
food components
CHEBI:78295
food component
dietary component
ChEBI
dietary components
ChEBI
food components
ChEBI
Any minor or unwanted substance introduced into the environment that can have undesired effects.
chebi_ontology
environmental contaminants
CHEBI:78298
environmental contaminant
environmental contaminants
ChEBI
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Wikipedia:Refrigerant
chebi_ontology
refrigerants
CHEBI:78433
refrigerant
refrigerants
ChEBI
Any compound that causes severe skin, eye and mucosal pain and irritation.
PMID:16168310
Wikipedia:Blister_agent
chebi_ontology
blister agent
blister agents
vesicants
CHEBI:78592
vesicant
PMID:16168310
Europe PMC
blister agent
ChEBI
blister agents
ChEBI
vesicants
ChEBI
An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3.
0
C2H4NO2R
74.059
74.02420
[NH3+]C([*])C([O-])=O
CHEBI:83409
MetaCyc:Alpha-Amino-Acids
chebi_ontology
an alpha-amino acid
CHEBI:78608
alpha-amino acid zwitterion
MetaCyc:Alpha-Amino-Acids
SUBMITTER
an alpha-amino acid
UniProt
Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation.
chebi_ontology
carbohydrates and derivatives
carbohydrates and their derivatives
CHEBI:78616
carbohydrates and carbohydrate derivatives
carbohydrates and derivatives
ChEBI
carbohydrates and their derivatives
ChEBI
Any metabolite produced by all living cells.
chebi_ontology
essential metabolite
essential metabolites
fundamental metabolites
CHEBI:78675
fundamental metabolite
essential metabolite
ChEBI
essential metabolites
ChEBI
fundamental metabolites
ChEBI
Any inorganic anion with a valency of three.
chebi_ontology
trivalent inorganic anions
CHEBI:79387
trivalent inorganic anion
trivalent inorganic anions
ChEBI
Any inorganic anion with a valency of two.
chebi_ontology
divalent inorganic anions
CHEBI:79388
divalent inorganic anion
divalent inorganic anions
ChEBI
Any inorganic anion with a valency of one.
chebi_ontology
monovalent inorganic anions
CHEBI:79389
monovalent inorganic anion
monovalent inorganic anions
ChEBI
An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
chebi_ontology
crustacean metabolites
CHEBI:83039
crustacean metabolite
crustacean metabolites
ChEBI
A Daphnia metabolite produced by the species Daphnia magna.
chebi_ontology
Daphnia magna metabolites
CHEBI:83056
Daphnia magna metabolite
Daphnia magna metabolites
ChEBI
A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
Wikipedia:Daphnia
chebi_ontology
Daphnia metabolites
CHEBI:83057
Daphnia metabolite
Daphnia metabolites
ChEBI
An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid.
0
O3SR2
80.06300
79.95681
[*]S(=O)(=O)O[*]
chebi_ontology
organosulfonate ester
organosulfonate esters
organosulfonic esters
CHEBI:83347
organosulfonic ester
organosulfonate ester
ChEBI
organosulfonate esters
ChEBI
organosulfonic esters
ChEBI
An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3.
-1
O4SR
96.064
95.95173
[O-]S(=O)(=O)O[*]
MetaCyc:Organo-Sulfates
chebi_ontology
alkyl sulfate anion
an alkyl sulfate
CHEBI:83414
alkyl sulfate(1-)
MetaCyc:Organo-Sulfates
SUBMITTER
alkyl sulfate anion
ChEBI
an alkyl sulfate
UniProt
Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom.
chebi_ontology
canonical amino acid derivative
canonical amino acid derivatives
canonical amino-acid derivative
canonical amino-acid derivatives
proteinogenic amino acid derivatives
proteinogenic amino-acid derivative
proteinogenic amino-acid derivatives
CHEBI:83811
proteinogenic amino acid derivative
canonical amino acid derivative
ChEBI
canonical amino acid derivatives
ChEBI
canonical amino-acid derivative
ChEBI
canonical amino-acid derivatives
ChEBI
proteinogenic amino acid derivatives
ChEBI
proteinogenic amino-acid derivative
ChEBI
proteinogenic amino-acid derivatives
ChEBI
Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom.
chebi_ontology
non-canonical amino acid derivative
non-canonical amino-acid derivatives
non-proteinogenic amino-acid derivatives
CHEBI:83812
non-proteinogenic amino acid derivative
non-canonical amino acid derivative
ChEBI
non-canonical amino-acid derivatives
ChEBI
non-proteinogenic amino-acid derivatives
ChEBI
Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration.
Wikipedia:Proteinogenic_amino_acid
chebi_ontology
canonical amino acid
canonical amino acids
proteinogenic amino acids
CHEBI:83813
proteinogenic amino acid
canonical amino acid
ChEBI
canonical amino acids
ChEBI
proteinogenic amino acids
ChEBI
Any amino-acid that is not naturally encoded in the genetic code of any organism.
Wikipedia:Non-proteinogenic_amino_acids
chebi_ontology
non-canonical amino acid
non-canonical amino acids
non-canonical amino-acid
non-canonical amino-acids
non-coded amino acid
non-coded amino acids
non-coded amino-acid
non-coded amino-acids
non-proteinogenic amino acids
non-proteinogenic amino-acid
non-proteinogenic amino-acids
CHEBI:83820
non-proteinogenic amino acid
non-canonical amino acid
ChEBI
non-canonical amino acids
ChEBI
non-canonical amino-acid
ChEBI
non-canonical amino-acids
ChEBI
non-coded amino acid
ChEBI
non-coded amino acids
ChEBI
non-coded amino-acid
ChEBI
non-coded amino-acids
ChEBI
non-proteinogenic amino acids
ChEBI
non-proteinogenic amino-acid
ChEBI
non-proteinogenic amino-acids
ChEBI
Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues.
CHEBI:25359
chebi_ontology
amino acid derivatives
modified amino acids
CHEBI:83821
amino acid derivative
amino acid derivatives
ChEBI
modified amino acids
ChEBI
Any L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
chebi_ontology
non-proteinogenic L-alpha-amino acids
CHEBI:83822
non-proteinogenic L-alpha-amino acid
non-proteinogenic L-alpha-amino acids
ChEBI
Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
chebi_ontology
non-proteinogenic alpha-amino acids
non-proteinogenic alpha-amino-acid
non-proteinogenic alpha-amino-acids
CHEBI:83925
non-proteinogenic alpha-amino acid
non-proteinogenic alpha-amino acids
ChEBI
non-proteinogenic alpha-amino-acid
ChEBI
non-proteinogenic alpha-amino-acids
ChEBI
A proteinogenic amino acid derivative resulting from reaction of L-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of L-glutamic acid by a heteroatom.
chebi_ontology
L-glutamic acid derivatives
CHEBI:83982
L-glutamic acid derivative
L-glutamic acid derivatives
ChEBI
A non-proteinogenic amino acid derivative resulting from reaction of D-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-phenylalanine by a heteroatom.
chebi_ontology
D-phenylalanine derivatives
CHEBI:84143
D-phenylalanine derivative
D-phenylalanine derivatives
ChEBI
A proteinogenic amino acid derivative resulting from reaction of L-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-phenylalanine by a heteroatom.
chebi_ontology
L-phenylalanine derivatives
CHEBI:84144
L-phenylalanine derivative
L-phenylalanine derivatives
ChEBI
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
chebi_ontology
algal metabolites
CHEBI:84735
algal metabolite
algal metabolites
ChEBI
Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin.
PMID:21265866
PMID:22132817
PMID:22314516
PMID:23891889
PMID:23974587
PMID:25535470
PMID:25574195
PMID:25643794
Wikipedia:Skin_whitening
chebi_ontology
melanogenesis inhibitor
melanogenesis inhibitors
skin bleaching agent
skin bleaching agents
skin depigmenting agent
skin depigmenting agents
skin lightening agents
skin whitening agent
skin whitening agents
CHEBI:85046
skin lightening agent
PMID:21265866
Europe PMC
PMID:22132817
Europe PMC
PMID:22314516
Europe PMC
PMID:23891889
Europe PMC
PMID:23974587
Europe PMC
PMID:25535470
Europe PMC
PMID:25574195
Europe PMC
PMID:25643794
Europe PMC
melanogenesis inhibitor
ChEBI
melanogenesis inhibitors
ChEBI
skin bleaching agent
ChEBI
skin bleaching agents
ChEBI
skin depigmenting agent
ChEBI
skin depigmenting agents
ChEBI
skin lightening agents
ChEBI
skin whitening agent
ChEBI
skin whitening agents
ChEBI
Any metabolite (endogenous or exogenous) found in human blood serum samples.
chebi_ontology
human blood serum metabolites
CHEBI:85234
human blood serum metabolite
human blood serum metabolites
ChEBI
A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
0
C23H30ClN3O
InChI=1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)
GPKJTRJOBQGKQK-UHFFFAOYSA-N
399.95700
399.20774
CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12
Beilstein:497807
Beilstein:95500
CAS:83-89-6
DrugBank:DB01103
Drug_Central:2338
HMDB:HMDB0015235
KEGG:C07339
KEGG:D08179
LINCS:LSM-1577
MetaCyc:ATABRINE
PMID:11339632
PMID:11908878
PMID:19747949
Reaxys:95500
Wikipedia:Quinacrine
4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine
Quinacrine
chebi_ontology
2-methoxy-6-chloro-9-diethylaminopentylaminoacridine
3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine
Mepacrine
N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
mepacrine
CHEBI:8711
quinacrine
Beilstein:497807
Beilstein
Beilstein:95500
Beilstein
CAS:83-89-6
ChemIDplus
CAS:83-89-6
KEGG COMPOUND
Drug_Central:2338
DrugCentral
PMID:11339632
Europe PMC
PMID:11908878
Europe PMC
PMID:19747949
Europe PMC
Reaxys:95500
Reaxys
4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine
IUPAC
Quinacrine
KEGG_COMPOUND
2-methoxy-6-chloro-9-diethylaminopentylaminoacridine
ChemIDplus
3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine
ChemIDplus
6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine
ChemIDplus
Mepacrine
KEGG_COMPOUND
N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
ChemIDplus
mepacrine
ChemIDplus
Any metal which causes the onset of an allergic reaction.
chebi_ontology
allergenic metal
allergenic metals
metal allergens
CHEBI:88184
metal allergen
allergenic metal
ChEBI
allergenic metals
ChEBI
metal allergens
ChEBI
Any drug which causes the onset of an allergic reaction.
chebi_ontology
allergenic drug
CHEBI:88188
drug allergen
allergenic drug
ChEBI
A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.
chebi_ontology
receptor modulators
CHEBI:90710
receptor modulator
receptor modulators
ChEBI
FlyBase miscellaneous CV
FBcv:0000000
FlyBase CV
pub_type
FBcv:0000001
This term was obsoleted because it was only ever used to annotate one publication: A copy of Calvin Bridges death certificate. This can still be found in the Drosophila offprint collection (FBrf0186653).
death certificate
true
Phenotype that is a defect in thermotaxis (GO:0043052). 'thermotaxis' is defined as: 'The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.'
thermotaxis behavior defective
thermotaxis behaviour defective
phenotypic_class
FBcv:0000002
thermotaxis defective
Phenotype that is a defect in thermotaxis (GO:0043052). 'thermotaxis' is defined as: 'The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.'
FBC:DOS
GOC:cab1
WB_REF:cgc467
FBcv:0000807
abbrev:1
mode_of_assay
FBcv:0000003
This term has been obsoleted because it is no longer used and relevant. mc151005
In transgenic Drosophila (intraspecific)
true
FBcv:0000807
abbrev:2
mode_of_assay
FBcv:0000004
This term has been obsoleted because it is no longer used and relevant. mc151005
Whole-organism transient assay (intraspecific)
true
Term used to qualify a descriptor.
FlyBase miscellaneous CV
FBcv:0000005
qualifier
Term used to qualify a descriptor.
FBC:MMC
Phenotype of males that is a reduction in the proportion of fertilized eggs produced, but only to > 50% of wild-type.
phenotypic_class
FBcv:0000006
male semi-fertile
Phenotype of females that is a reduction in the proportion of fertilized eggs produced, but only to > 50% of wild-type.
phenotypic_class
FBcv:0000007
female semi-fertile
Genotype g1 is a modifier of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is significantly different from that caused by g2 alone.
phenotypic_class
variegation
FBcv:0000008
modifier of variegation
Genotype g1 is a modifier of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is significantly different from that caused by g2 alone.
FBC:DOS
variegation
FBC:DOS
FBcv:0000176
PATO:0000083
temporal_qualifier
FBcv:0000009
This term has been obsoleted because all of its children terms have been obsoleted [FBC:MMC]. mc161027
temporal stage qualifier
true
FBcv:0000176
PATO:0001773
FlyBase miscellaneous CV
FBcv:0000010
This term has been obsoleted because there are new terms to replace it [FBC:MMC]. mc160113
monophasic
true
FBcv:0000176
temporal_qualifier
FBcv:0000011
This term has been obsoleted because all of its children terms have been obsoleted [FBC:MMC]. mc161027
relative temporal qualifier
true
FBcv:0000176
PATO:0000165
FlyBase miscellaneous CV
FBcv:0000012
This term has been obsoleted because both of its children terms have been obsoleted [FBC:MMC]. mc160113
absolute temporal qualifier
true
Term that describes an allele, balancer, group or publication.
FlyBase miscellaneous CV
FBcv:0000013
descriptor
Term that describes an allele, balancer, group or publication.
FBC:MMC
Qualifier used to describe the appearance of extra copies of an anatomical structure.
structural_qualifier
FBcv:0000014
structural qualifier
Qualifier used to describe the appearance of extra copies of an anatomical structure.
FBC:MMC
pub_type
FBcv:0000015
This term was obsoleted because it was little used.
postage stamp
true
FlyBase miscellaneous CV
FBcv:0000016
Consider - FBsv:0000605.
Baylor TE recombination mapping kit stock
true
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000017
penetrance qualifier
true
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is complete when all the individuals of a given genotype exhibit the phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000018
penetrance complete
true
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is complete when all the individuals of a given genotype exhibit the phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only some the individuals of a given genotype exhibit the phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000019
penetrance incomplete
true
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only some the individuals of a given genotype exhibit the phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only a percentage of the individuals of a given genotype exhibit the phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000020
This term should be modified by a % value. This is not currently possible in FlyBase curation.
penetrance percent
true
Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only a percentage of the individuals of a given genotype exhibit the phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level.
FlyBase miscellaneous CV
FBcv:0000021
expressivity qualifier
true
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level.
ISBN:978-0-7167-3520-5
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is complete when an individual of a given genotype expresses the full phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000022
expressivity complete
true
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is complete when an individual of a given genotype expresses the full phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is incomplete when an individual of a given genotype expresses only partially the phenotype associated with that genotype.
FlyBase miscellaneous CV
FBcv:0000023
expressivity incomplete
true
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is incomplete when an individual of a given genotype expresses only partially the phenotype associated with that genotype.
ISBN:978-0-7167-3520-5
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'High expressivity' conveys that while expressivity is not complete, the phenotype expressed is approaching that of complete expressivity.
FlyBase miscellaneous CV
FBcv:0000024
expressivity high
true
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'High expressivity' conveys that while expressivity is not complete, the phenotype expressed is approaching that of complete expressivity.
ISBN:978-0-7167-3520-5
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'Low expressivity' conveys that phenotype expressed is a much reduced version compared to complete expressivity.
FlyBase miscellaneous CV
FBcv:0000025
expressivity low
true
Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'Low expressivity' conveys that phenotype expressed is a much reduced version compared to complete expressivity.
ISBN:978-0-7167-3520-5
FlyBase miscellaneous CV
FBcv:0000026
recessive visible allele recombination mapping stock
true
FlyBase miscellaneous CV
FBcv:0000027
dominant visible allele recombination mapping stock
true
FlyBase miscellaneous CV
FBcv:0000028
Consider - FBsv:0001018.
SNP recombination mapping stock
true
FlyBase miscellaneous CV
FBcv:0000029
transposable element mutagenesis stock
true
FBcv:0000052
spatial_qualifier
FBcv:0000030
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
compartment
true
FBcv:0000052
spatial_qualifier
FBcv:0000031
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
anterior compartment
true
FBcv:0000052
spatial_qualifier
FBcv:0000032
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
compartment boundary
true
FBcv:0000052
spatial_qualifier
FBcv:0000033
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
anterior/posterior compartment boundary
true
FBcv:0000052
spatial_qualifier
FBcv:0000034
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
dorsal/ventral compartment boundary
true
FBcv:0000052
spatial_qualifier
FBcv:0000035
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
dorsal compartment
true
FBcv:0000052
spatial_qualifier
FBcv:0000036
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
posterior compartment
true
FBcv:0000052
spatial_qualifier
FBcv:0000037
This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027
ventral compartment
true
PATO:0001631
spatial_qualifier
FBcv:0000038
relative spatial qualifier
PATO:0001632
spatial_qualifier
FBcv:0000039
anterior to
PATO:0001234
spatial_qualifier
FBcv:0000040
distal to
PATO:0001233
spatial_qualifier
FBcv:0000041
dorsal to
FlyBase miscellaneous CV
deletion kit stock
FBcv:0000042
deficiency kit stock
true
FlyBase miscellaneous CV
FBcv:0000043
Consider - FBsv:0001020.
transposase source for transposable element mutagenesis
true
FlyBase miscellaneous CV
FBcv:0000044
Consider - FBsv:0001022.
ammunition source for transposable element mutagenesis
true
PATO:0001633
spatial_qualifier
FBcv:0000045
posterior to
temporal_qualifier
FBcv:0000046
precursor
PATO:0001195
spatial_qualifier
FBcv:0000047
proximal to
PATO:0001772
spatial_qualifier
FBcv:0000048
surrounding
PATO:0001196
spatial_qualifier
FBcv:0000049
ventral to
PATO:0001771
spatial_qualifier
FBcv:0000050
vicinity of
Present in the area that separates segments.
spatial_qualifier
FBcv:0000051
segment boundary
Present in the area that separates segments.
FBC:MMC
Qualifier that describes the spatial characteristics of a phenotype or expression pattern.
spatial_qualifier
FBcv:0000052
spatial qualifier
Qualifier that describes the spatial characteristics of a phenotype or expression pattern.
FBC:MMC
Restricted to anterior region of some specified type.
spatial_qualifier
FBcv:0000053
anterior
Restricted to anterior region of some specified type.
FBC:DS
Restricted to apical region of some specified type.
spatial_qualifier
FBcv:0000054
apical
Restricted to apical region of some specified type.
FBC:DS
Restricted to basal region of some specified type.
spatial_qualifier
FBcv:0000055
basal
Restricted to basal region of some specified type.
FBC:DS
Restricted to central region of some specified type.
spatial_qualifier
FBcv:0000056
central
Restricted to central region of some specified type.
FBC:DS
FBcv:0000052
spatial_qualifier
FBcv:0000057
This term has been obsoleted because there is no way to combine it with an anatomy term to produce a meaningful statement [FBC:MMC]. mc160113.
contralateral
true
Restricted to distal region of some specified type.
spatial_qualifier
FBcv:0000058
distal
Restricted to distal region of some specified type.
FBC:DS
Restricted to dorsal region of some specified type.
spatial_qualifier
FBcv:0000059
dorsal
Restricted to dorsal region of some specified type.
FBC:DS
Restricted to dorso-lateral region of some specified type.
spatial_qualifier
FBcv:0000060
dorso-lateral
Restricted to dorso-lateral region of some specified type.
FBC:DS
When, compared to wild-type, an extra copy of an anatomical structure is present in an abnormal location, then this structure is ectopic.
structural_qualifier
FBcv:0000061
An extra copy of an anatomical structure that is present in the same location as in wild-type is supernumerary, rather than ectopic.
ectopic
When, compared to wild-type, an extra copy of an anatomical structure is present in an abnormal location, then this structure is ectopic.
FBC:DOS
FBcv:0000052
spatial_qualifier
FBcv:0000062
This term has been obsoleted because there is no way to combine it with an anatomy term to produce a meaningful statement [FBC:MMC]. mc161027
ipsilateral
true
Restricted to lateral region(s) of some specified type.
spatial_qualifier
FBcv:0000063
lateral
Restricted to lateral region(s) of some specified type.
FBC:DS
Restricted to medial region of some specified type.
spatial_qualifier
FBcv:0000064
medial
Restricted to medial region of some specified type.
FBC:DS
Restricted to posterior region of some specified type.
spatial_qualifier
FBcv:0000065
posterior
Restricted to posterior region of some specified type.
FBC:DS
Restricted to proximal region of some specified type.
spatial_qualifier
FBcv:0000066
proximal
Restricted to proximal region of some specified type.
FBC:DS
Restricted to unknown part(s) of a specified type.
spatial_qualifier
FBcv:0000067
restricted
Restricted to unknown part(s) of a specified type.
FBC:DS
Present in the correct location but in larger numbers than in wild-type.
structural_qualifier
FBcv:0000068
supernumerary
Present in the correct location but in larger numbers than in wild-type.
FBC:DOS
Expressed everywhere at some specified stage.
spatial_qualifier
FBcv:0000069
ubiquitous
Expressed everywhere at some specified stage.
FBC:DOS
Restricted to ventral region of some specified type.
spatial_qualifier
FBcv:0000070
ventral
Restricted to ventral region of some specified type.
FBC:DS
Restricted to ventro-lateral region of some specified type.
spatial_qualifier
FBcv:0000071
ventro-lateral
Restricted to ventro-lateral region of some specified type.
FBC:DS
FlyBase miscellaneous CV
FBcv:0000072
gene expression qualifier
true
FlyBase miscellaneous CV
FBcv:0000073
embryonic expression pattern
true
Position in the egg or pre-gastrula embryo expressed as a percentage of egg length, where 0% corresponds to the posterior tip and 100% to the anterior tip.
spatial_qualifier
FBcv:0000074
egg length
Position in the egg or pre-gastrula embryo expressed as a percentage of egg length, where 0% corresponds to the posterior tip and 100% to the anterior tip.
FBC:DOS
At the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000075
0% egg length
At the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000076
0-10% egg length
0-10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
The full length of the pre-gastrula embryo.
spatial_qualifier
FBcv:0000077
0-100% egg length
The full length of the pre-gastrula embryo.
FBC:DOS
0-20% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000078
0-20% egg length
0-20% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-30% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000079
0-30% egg length
0-30% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-40% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000080
0-40% egg length
0-40% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-50% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000081
0-50% egg length
0-50% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-60% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000082
0-60% egg length
0-60% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-70% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000083
0-70% egg length
0-70% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-80% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000084
0-80% egg length
0-80% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
0-90% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000085
0-90% egg length
0-90% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000086
10% egg length
10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
10-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000087
10-100% egg length
10-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-20% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000088
10-20% egg length
10-20% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000089
10-30% egg length
10-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000090
10-40% egg length
10-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000091
10-50% egg length
10-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000092
10-60% egg length
10-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000093
10-70% egg length
10-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000094
10-80% egg length
10-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
10-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000095
10-90% egg length
10-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
At the anterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000096
100% egg length
At the anterior tip of the egg or pre-gastrula embryo.
FBC:DOS
10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000097
20% egg length
10% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
20-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000098
20-100% egg length
20-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000099
20-30% egg length
20-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000100
20-40% egg length
20-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000101
20-50% egg length
20-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000102
20-60% egg length
20-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000103
20-70% egg length
20-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000104
20-80% egg length
20-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
20-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000105
20-90% egg length
20-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000106
30% egg length
30% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
30-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000107
30-100% egg length
30-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000108
30-40% egg length
30-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000109
30-50% egg length
30-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000110
30-60% egg length
30-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000111
30-70% egg length
30-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000112
30-80% egg length
30-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
30-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000113
30-90% egg length
30-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000114
40% egg length
40% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
40-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000115
40-100% egg length
40-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000116
40-50% egg length
40-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000117
40-60% egg length
40-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000118
40-70% egg length
40-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000119
40-80% egg length
40-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
40-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000120
40-90% egg length
40-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
50% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000121
50% egg length
50% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
50-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000122
50-100% egg length
50-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
50-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000123
50-60% egg length
50-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
50-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000124
50-70% egg length
50-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
50-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000125
50-80% egg length
50-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
50-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000126
50-90% egg length
50-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
60% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000127
60% egg length
60% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
60-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000128
60-100% egg length
60-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
60-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000129
60-80% egg length
60-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
60-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000130
60-90% egg length
60-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
70% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000131
70% egg length
70% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
70-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000132
70-100% egg length
70-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
70-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000133
70-80% egg length
70-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
70-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000134
70-90% egg length
70-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
80% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000135
80% egg length
80% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
80-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000136
80-90% egg length
80-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
90% of egg length from the posterior tip of the egg or pre-gastrula embryo.
spatial_qualifier
FBcv:0000137
90% egg length
90% of egg length from the posterior tip of the egg or pre-gastrula embryo.
FBC:DOS
true
90-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBcv:0000138
spatial_qualifier
90-100% egg length
FBcv:0000139
90-100% egg length
90-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
A record of an analysis carried out by FlyBase that has not been formally published.
pub_type
FBcv:0000140
FlyBase analysis
A record of an analysis carried out by FlyBase that has not been formally published.
FBC:SM
Expression pattern which varies in intensity following a gradient in a specific axis.
spatial_qualifier
FBcv:0000141
gradient
Expression pattern which varies in intensity following a gradient in a specific axis.
FBC:MMC
Expression pattern which varies in intensity following a gradient in the anterior-posterior axis.
spatial_qualifier
FBcv:0000142
anterior posterior gradient
Expression pattern which varies in intensity following a gradient in the anterior-posterior axis.
FBC:MMC
Expression pattern which varies in intensity following a gradient in the dorsal-ventral axis.
spatial_qualifier
FBcv:0000143
dorsal ventral gradient
Expression pattern which varies in intensity following a gradient in the dorsal-ventral axis.
FBC:MMC
FlyBase miscellaneous CV
FBcv:0000144
maternal pattern
true
Restricted to stripes in some specified type.
spatial_qualifier
FBcv:0000145
striped
Restricted to stripes in some specified type.
FBC:DS
Sequence change caused by the cleavage of a 19-24 bp palindromic DNA site by the I-CreI endonuclease.
change induced by I-CreI endonuclease cleavage
origin_of_mutation
FBcv:0000146
I-CreI
Sequence change caused by the cleavage of a 19-24 bp palindromic DNA site by the I-CreI endonuclease.
UniProt:P05725
Expression in even, but not odd numbered segment of the blastoderm.
embryonic_pattern_qualifier
FBcv:0000147
even pair rule expression pattern
Expression in even, but not odd numbered segment of the blastoderm.
FBC:DOS
Expression in odd, but not even numbered segments of the blastoderm.
embryonic_pattern_qualifier
FBcv:0000148
odd pair rule expression pattern
Expression in odd, but not even numbered segments of the blastoderm.
FBC:DOS
A list of species found in a specified area.
pub_type
FBcv:0000149
species list
A list of species found in a specified area.
FBC:SM
Restricted to a segmentally repeated pattern with some specified type.
spatial_qualifier
FBcv:0000150
segmentally repeated
Restricted to a segmentally repeated pattern with some specified type.
FBC:DOS
pub_type
FBcv:0000151
This term was obsoleted because there because there were no instances of its use to classify any artefact in FlyBase.
archive
true
A stock with one or more chromosomes (balancers) that are used primarily for their ability to preserve a stock genotype without selection.
FlyBase miscellaneous CV
FBcv:0000152
Consider - FBsv:0001001.
balancer stock
true
A stock with one or more chromosomes (balancers) that are used primarily for their ability to preserve a stock genotype without selection.
FBC:KM
A phenotypic effect which is expressed in and limited to cells of the mutant genetic constitution under investigation is said to be cell autonomous.
genotype_to_phenotype_relation
FBcv:0000153
cell autonomous
A phenotypic effect which is expressed in and limited to cells of the mutant genetic constitution under investigation is said to be cell autonomous.
FlyBase:FBrf0002379
A phenotypic effect which is not expressed in/limited to cells of the mutant genetic constitution under investigation is said to be cell non-autonomous.
genotype_to_phenotype_relation
FBcv:0000154
cell non-autonomous
A phenotypic effect which is not expressed in/limited to cells of the mutant genetic constitution under investigation is said to be cell non-autonomous.
FlyBase:FBrf0002379
Chromosome that carries inversions and visible mutations, and which can be used to identify the genotype of an individual.
FlyBase miscellaneous CV
FBcv:0000155
single balancer
Chromosome that carries inversions and visible mutations, and which can be used to identify the genotype of an individual.
FlyBase:FBrf0089469
FlyBase:FBrf0202435
FlyBase miscellaneous CV
FBcv:0000156
pair of homologous balancers
true
FlyBase miscellaneous CV
FBcv:0000157
recessive lethal balancer
true
FlyBase miscellaneous CV
FBcv:0000158
Consider - FBsv:0001006.
balancer for chromosome 1
true
FlyBase miscellaneous CV
FBcv:0000159
Consider - FBsv:0001007.
balancer for chromosome 2
true
FlyBase miscellaneous CV
FBcv:0000160
Consider - FBsv:0001008.
balancer for chromosome 3
true
A phenotypic attribute is described as showing a maternal effect when the phenotype of an individual is a manifestation of the genotype of the mother, rather than the genotype of the individual.
genotype_to_phenotype_relation
FBcv:0000161
maternal effect
A phenotypic attribute is described as showing a maternal effect when the phenotype of an individual is a manifestation of the genotype of the mother, rather than the genotype of the individual.
ISBN:978-0-7167-3520-5
A phenotypic attribute is described as showing a non-rescuable maternal effect (strict maternal effect) when the introduction of a wild-type copy of the responsible mutation from the father has no ameliorating effect on the maternal effect mutant phenotype.
genotype_to_phenotype_relation
FBcv:0000162
non-rescuable maternal effect
A phenotypic attribute is described as showing a non-rescuable maternal effect (strict maternal effect) when the introduction of a wild-type copy of the responsible mutation from the father has no ameliorating effect on the maternal effect mutant phenotype.
FlyBase:FBrf0049894
A phenotypic attribute is described as showing a rescuable maternal effect when the introduction of a wild-type copy of the responsible mutation from the father ameliorates the maternal effect mutant phenotype.
genotype_to_phenotype_relation
FBcv:0000163
rescuable maternal effect
A phenotypic attribute is described as showing a rescuable maternal effect when the introduction of a wild-type copy of the responsible mutation from the father ameliorates the maternal effect mutant phenotype.
FlyBase:FBrf0049894
A phenotypic attribute is described as showing a paternal effect when the phenotype of an individual is a manifestation of the genotype of the father, rather than the genotype of the individual.
genotype_to_phenotype_relation
FBcv:0000164
paternal effect
A phenotypic attribute is described as showing a paternal effect when the phenotype of an individual is a manifestation of the genotype of the father, rather than the genotype of the individual.
FlyBase:FBrf0102738
FlyBase miscellaneous CV
FBcv:0000165
pair of balancers for chromosome 2
true
Qualifier that describes an observed expression pattern.
expression_qualifier
FBcv:0000166
morphological qualifier
Qualifier that describes an observed expression pattern.
FBC:MMC
Weak expression.
expression_qualifier
FBcv:0000167
faint
Weak expression.
FBC:MMC
Expression pattern that resembles small grains or particles.
PATO:0001759
expression_qualifier
FBcv:0000168
granular
Expression pattern that resembles small grains or particles.
FBC:MMC
Strong expression.
PATO:0000049
expression_qualifier
FBcv:0000169
intense
Strong expression.
FBC:MMC
Expression pattern that resembles small dots.
PATO:0001512
expression_qualifier
FBcv:0000170
punctate
Expression pattern that resembles small dots.
FBC:MMC
Expression pattern that is constant throughout the assayed anatomical entity.
PATO:0000438
expression_qualifier
FBcv:0000171
uniform
Expression pattern that is constant throughout the assayed anatomical entity.
FBC:MMC
Expression pattern that changes throughout the assayed anatomical entity.
PATO:0001227
expression_qualifier
FBcv:0000172
variable
Expression pattern that changes throughout the assayed anatomical entity.
FBC:MMC
FlyBase miscellaneous CV
FBcv:0000173
pair of balancers for chromosome 3
true
FlyBase miscellaneous CV
FBcv:0000174
Consider - FBsv:0001012.
dominant male sterile balancer
true
FlyBase miscellaneous CV
FBcv:0000175
Consider - FBsv:0001012.
dominant female sterile balancer
true
temporal_qualifier
FBcv:0000176
temporal qualifier
FlyBase miscellaneous CV
FBcv:0000177
dominant female sterile balancer for chromosome 2
true
FBcv:0000176
PATO:0000694
temporal_qualifier
FBcv:0000178
This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027
early
true
FlyBase miscellaneous CV
FBcv:0000179
dominant female sterile balancer for chromosome 3
true
FlyBase miscellaneous CV
FBcv:0000180
dominant male sterile balancer for chromosome 2
true
FBcv:0000176
PATO:0000502
temporal_qualifier
FBcv:0000181
This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027
late
true
FBcv:0000176
temporal_qualifier
FBcv:0000182
This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027
mid
true
FBcv:0000176
FlyBase miscellaneous CV
FBcv:0000183
This term has been obsoleted because there are new stage terms that can be used instead [FBC:MMC]. mc160113
n day
true
FBcv:0000176
FlyBase miscellaneous CV
FBcv:0000184
This term has been obsoleted because there are new stage terms that can be used instead [FBC:MMC]. mc160113
n hr
true
FlyBase miscellaneous CV
FBcv:0000185
dominant male sterile balancer for chromosome 3
true
FlyBase miscellaneous CV
FBcv:0000186
recessive lethal balancer for chromosome 1
true
FlyBase miscellaneous CV
FBcv:0000187
recessive lethal balancer for chromosome 2
true
Qualifier that describes the type of publication.
FlyBase miscellaneous CV
FBcv:0000188
publication descriptor
Qualifier that describes the type of publication.
FBC:MMC
A publicly available document. It includes individual articles, such as research papers and reviews, and collections of articles, such as scientific journals.
pub_type
FBcv:0000189
publication class
A publicly available document. It includes individual articles, such as research papers and reviews, and collections of articles, such as scientific journals.
FBC:DOS
FBC:SM
An individual abstract of a presentation at a meeting, congress, conference, symposium, colloquium, seminar, workshop, round table, or other professional gathering.
MeSH:D016416
Meeting Abstracts
pub_type
FBcv:0000190
abstract
An individual abstract of a presentation at a meeting, congress, conference, symposium, colloquium, seminar, workshop, round table, or other professional gathering.
MeSH:D016416
Meeting Abstracts
MeSH:D016416
pub_type
FBcv:0000191
This term was obsoleted because it only ever used to annotate a couple of publications.
advertisement
true
A work consisting of a self-described account.
MeSH:D020493
pub_type
FBcv:0000192
autobiography
A work consisting of a self-described account.
MeSH:D020493
A work consisting of a list of books, articles, documents, publications, and other items, usually on a single subject or related subjects.
MeSH:D016417
Bibliography
pub_type
FBcv:0000193
bibliographic list
A work consisting of a list of books, articles, documents, publications, and other items, usually on a single subject or related subjects.
MeSH:D016417
Bibliography
MeSH:D016417
A work consisting of an account of the events, works, and achievements, personal and professional, during a person's life. This class includes articles on the activities and accomplishments of living persons as well as the presentation of an obituary.
MeSH:D019215
pub_type
FBcv:0000194
biography
A work consisting of an account of the events, works, and achievements, personal and professional, during a person's life. This class includes articles on the activities and accomplishments of living persons as well as the presentation of an obituary.
MeSH:D019215
A publication on a single subject or related subjects that is complete in itself, whether constructed of chapters, sections, or parts, and that is not issued on a regular, ongoing basis. Every chapter is written by the same author or authors of the publication.
pub_type
FBcv:0000195
For books (in the common sense of the term) that have different authors for each chapter, please use 'edited book'.
book
A publication on a single subject or related subjects that is complete in itself, whether constructed of chapters, sections, or parts, and that is not issued on a regular, ongoing basis. Every chapter is written by the same author or authors of the publication.
FBC:SM
pub_type
FBcv:0000196
This term was obsoleted because it was little used in curation. The formerly associated publications have mainly been annotated with other, more appropriate publication classes.
booklet
true
A work consisting of a critical analysis of one or more books or other monographic works.
MeSH:D022921
Book Reviews
pub_type
FBcv:0000197
book review
A work consisting of a critical analysis of one or more books or other monographic works.
MeSH:D022921
Book Reviews
MeSH:D022921
pub_type
CD-ROM
FBcv:0000198
computer file
true
The published records of the papers delivered at or issued on the occasion of individual congresses, symposia, and meetings; abstracts of papers delivered at such congresses; reports of the officers and delegates of such congresses; combinations of the foregoing; or proceedings of the conference of a society if they are not limited to matters of internal organization.
MeSH:D016423
Congresses
conference proceedings
meeting report
pub_type
FBcv:0000199
The definition is taken straight from the MeSH term Congresses, which PubMed uses to annotate both meeting reports written by attendees and conference abstract books. This term should therefore be used to index both of these two rather different artefacts.
conference report
The published records of the papers delivered at or issued on the occasion of individual congresses, symposia, and meetings; abstracts of papers delivered at such congresses; reports of the officers and delegates of such congresses; combinations of the foregoing; or proceedings of the conference of a society if they are not limited to matters of internal organization.
MeSH:D016423
Congresses
MeSH:D016423
pub_type
FBcv:0000200
This term was obsoleted because it was little used. All publications associated with it have been re-annotated with other publication classes.
demonstration
true
A record of a DNA or RNA sequence in some standard format, such as GenBank or EMBL or DDBJ.
pub_type
FBcv:0000201
DNA/RNA sequence record
A record of a DNA or RNA sequence in some standard format, such as GenBank or EMBL or DDBJ.
FBC:DOS
FBC:SM
A record of a protein sequence in some standard format, such as UniProtKB.
pub_type
FBcv:0000202
protein sequence record
A record of a protein sequence in some standard format, such as UniProtKB.
FBC:SM
A work consisting of an acknowledgement of an error, issued by a publisher, editor, or author.
MeSH:D016425
Corrigendum
Published Erratum
correction
pub_type
FBcv:0000203
erratum
A work consisting of an acknowledgement of an error, issued by a publisher, editor, or author.
MeSH:D016425
Corrigendum
MeSH:D016425
Published Erratum
MeSH:D016425
A film or video that is factual, documentary or instructional in character.
video
pub_type
FBcv:0000204
film
A film or video that is factual, documentary or instructional in character.
FBC:SM
MeSH:D019499
MeSH:D019514
A work consisting of a conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by the interviewer.
MeSH:D017203
pub_type
FBcv:0000205
interview
A work consisting of a conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by the interviewer.
MeSH:D017203
pub_type
FBcv:0000206
This term was obsoleted because it only ever used to annotate one, unarchived publication.
jigsaw puzzle
true
A work consisting of written or printed communication between individuals or between persons and representatives of corporate bodies. The correspondence may be personal or professional.
MeSH:D016422
pub_type
FBcv:0000207
In medical and other scientific publications the letter is usually from one or more authors to the editor of the journal or book publishing the item being commented upon or discussed.
letter
A work consisting of written or printed communication between individuals or between persons and representatives of corporate bodies. The correspondence may be personal or professional.
MeSH:D016422
pub_type
FBcv:0000208
This term was obsoleted because it had only been used once in FlyBase, and this was for an artefact that is not present in a FlyBase associated archive. The associated record in FlyBase CHADO has been obsoleted.
microscope slides
true
A work consisting of an announcement or statement of recent or current events of new data and matters of interest in the field of medicine or science, published in a scientific journal.
MeSH:D016433
pub_type
FBcv:0000209
news article
A work consisting of an announcement or statement of recent or current events of new data and matters of interest in the field of medicine or science, published in a scientific journal.
FBC:SM
MeSH:D016433
A work consisting of a critical or explanatory note written to discuss, support, or dispute an article or other presentation previously published.
MeSH:D016420
Comment
pub_type
FBcv:0000210
note
A work consisting of a critical or explanatory note written to discuss, support, or dispute an article or other presentation previously published.
MeSH:D016420
Comment
MeSH:D016420
A published announcement of a death accompanied by a short biography of the deceased.
pub_type
FBcv:0000211
obituary
A published announcement of a death accompanied by a short biography of the deceased.
FBC:SM
An article reporting original research, published in a peer-reviewed journal.
Journal article
MeSH:D016428
pub_type
FBcv:0000212
Note that this is a much more specific class than that referred to by MeSH Journal article (D016428).
paper
An article reporting original research, published in a peer-reviewed journal.
FBC:SM
Journal article
MeSH:D016428
A work consisting of documents granted by a government giving exclusive rights to an inventor or assignee to manufacture, use, or sell an invention for a certain number of years.
MeSH:D020490
pub_type
FBcv:0000213
patent
A work consisting of documents granted by a government giving exclusive rights to an inventor or assignee to manufacture, use, or sell an invention for a certain number of years.
MeSH:D020490
A work that has not been formally published and that consists of observations or data submitted by a researcher or group of researchers directly to FlyBase.
pub_type
FBcv:0000214
personal communication to FlyBase
A work that has not been formally published and that consists of observations or data submitted by a researcher or group of researchers directly to FlyBase.
FBC:DOS
FBC:SM
A literary or oral work expressing meaning via symbolism and following formal or informal patterns.
MeSH:D055821
poetry
pub_type
FBcv:0000215
poem
A literary or oral work expressing meaning via symbolism and following formal or informal patterns.
MeSH:D055821
poetry
MeSH:D055821
A work consisting of a single or multi-sheet notice made to attract attention to events, activities, causes, goods, or services. It is for posting, usually in a public place and is chiefly pictorial. It is intended to make an immediate impression from a distance.
MeSH:D019519
pub_type
FBcv:0000216
The class does not encompass poster presentations at conferences and meetings.
poster
A work consisting of a single or multi-sheet notice made to attract attention to events, activities, causes, goods, or services. It is for posting, usually in a public place and is chiefly pictorial. It is intended to make an immediate impression from a distance.
MeSH:D019519
A written or recorded communication directed at members of the news media for the purpose of announcing something ostensibly newsworthy.
pub_type
FBcv:0000217
press release
A written or recorded communication directed at members of the news media for the purpose of announcing something ostensibly newsworthy.
http://en.wikipedia.org/w/index.php?title=Press_release&oldid=482495713
pub_type
FBcv:0000218
This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive. Records annotated with this term have been obsoleted in the FlyBase CHADO database.
recording
true
A work consisting of a statement issued by one or more authors of an article or a book, withdrawing or disavowing acknowledgement of their participation in performing research or writing the results of their study.
MeSH:D016440
Retraction of Publication
pub_type
FBcv:0000219
retraction
A work consisting of a statement issued by one or more authors of an article or a book, withdrawing or disavowing acknowledgement of their participation in performing research or writing the results of their study.
MeSH:D016440
Retraction of Publication
MeSH:D016440
An article or book published after examination of published material on a subject.
MeSH:D016454
pub_type
FBcv:0000220
The reviews most often desired are reviews of the current literature, but a review of historical literature is also within the scope of this publication type.
review
An article or book published after examination of published material on a subject.
MeSH:D016454
pub_type
FBcv:0000221
This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive.
slides
true
A mildly satirical mockery or parody of a conventional publication type.
MeSH:D020480
pub_type
FBcv:0000222
spoof
A mildly satirical mockery or parody of a conventional publication type.
FBC:SM
A list of Drosophila stocks kept by a specified stock center or research group.
pub_type
FBcv:0000223
stock list
A list of Drosophila stocks kept by a specified stock center or research group.
FBC:SM
Supporting content or information, such as animation, datasets, multimedia files, video, movies, audio files, text files, or software, which is submitted for publication in an online journal or an online edition of a journal. This information may be referenced in the text of the article with a link to the supplementary data provided.
MeSH:D058537
Electronic Supplementary Materials
additional files
supplementary information
supporting information
pub_type
FBcv:0000224
supplementary material
Supporting content or information, such as animation, datasets, multimedia files, video, movies, audio files, text files, or software, which is submitted for publication in an online journal or an online edition of a journal. This information may be referenced in the text of the article with a link to the supplementary data provided.
MeSH:D058537
Electronic Supplementary Materials
MeSH:D058537
pub_type
FBcv:0000225
This term was obsoleted because it had been used only once in ~20 years of curation.
T-shirt
true
A diagram that is designed to be touched, rather than looked at. These are generally made for use by blind or visually impaired people.
pub_type
FBcv:0000226
tactile diagram
true
A diagram that is designed to be touched, rather than looked at. These are generally made for use by blind or visually impaired people.
FBC:DOS
An article describing exercises or practicals suitable for teaching.
pub_type
FBcv:0000227
teaching note
An article describing exercises or practicals suitable for teaching.
FBC:SM
A work consisting of a formal presentation made usually to fulfill requirements for an academic degree.
MeSH:D019478
Academic Dissertations
pub_type
FBcv:0000228
thesis
A work consisting of a formal presentation made usually to fulfill requirements for an academic degree.
MeSH:D019478
Academic Dissertations
MeSH:D019478
A systematic effort to annotate gene models on a sequenced Drosophila genome, such as those conducted for D. melanogaster at the Celera Jamboree. Annotations may be performed manually or automatically.
pub_type
automatic genome annotation
FBcv:0000229
Note that the name of this publication type will change to simply 'genome annotation', but this change has been delayed pending required work on the database.
curated genome annotation
A systematic effort to annotate gene models on a sequenced Drosophila genome, such as those conducted for D. melanogaster at the Celera Jamboree. Annotations may be performed manually or automatically.
FBC:SM
FBcv:0000229
pub_type
FBcv:0000230
This term was obsoleted because it was hardly ever used. Please use FBcv:0000229 instead.
automatic genome annotation
true
A work consisting of a set of statements, directions, or principles presenting current or future rules or policy.
Guideline
MeSH:D016431
pub_type
FBcv:0000231
white paper
A work consisting of a set of statements, directions, or principles presenting current or future rules or policy.
FBC:SM
MeSH:D016431
Guideline
MeSH:D016431
FlyBase miscellaneous CV
FBcv:0000232
recessive lethal balancer for chromosome 3
true
A work that has not been formally published.
MeSH:D022902
Unpublished Works
pub_type
privately distributed report
FBcv:0000233
unpublished
A work that has not been formally published.
MeSH:D022902
Unpublished Works
MeSH:D022902
Qualifier that describes the language of the publication.
language
FBcv:0000234
publication language
Qualifier that describes the language of the publication.
FBC:MMC
Publication in the Afrikaans language.
language
FBcv:0000235
Afrikaans
Publication in the Afrikaans language.
FBC:MMC
Publication in the Arabic language.
language
FBcv:0000236
Arabic
Publication in the Arabic language.
FBC:MMC
Publication in the Armenian language.
language
FBcv:0000237
Armenian
Publication in the Armenian language.
FBC:MMC
Publication in the Belarussian language.
language
Belarusian
FBcv:0000238
Belarussian
Publication in the Belarussian language.
FBC:MMC
Publication in the Bulgarian language.
language
FBcv:0000239
Bulgarian
Publication in the Bulgarian language.
FBC:MMC
Publication in the Catalan language.
language
FBcv:0000240
Catalan
Publication in the Catalan language.
FBC:MMC
Publication in the Chinese language.
language
FBcv:0000241
Chinese
Publication in the Chinese language.
FBC:MMC
Publication in the Cumbrian language.
language
FBcv:0000242
Cumbrian
Publication in the Cumbrian language.
FBC:MMC
Publication in the Czech language.
language
FBcv:0000243
Czech
Publication in the Czech language.
FBC:MMC
Publication in the Danish language.
language
FBcv:0000244
Danish
Publication in the Danish language.
FBC:MMC
Publication in the Dutch language.
language
FBcv:0000245
Dutch
Publication in the Dutch language.
FBC:MMC
Publication in the English language.
language
FBcv:0000246
English
Publication in the English language.
FBC:MMC
Publication in the Estonian language.
language
FBcv:0000247
Estonian
Publication in the Estonian language.
FBC:MMC
Publication in the Faroese language.
language
FBcv:0000248
Faroese
Publication in the Faroese language.
FBC:MMC
Publication in the Farsi language.
language
FBcv:0000249
Farsi
Publication in the Farsi language.
FBC:MMC
Publication in the Finnish language.
language
FBcv:0000250
Finnish
Publication in the Finnish language.
FBC:MMC
Publication in the Flemish language.
language
FBcv:0000251
Flemish
Publication in the Flemish language.
FBC:MMC
Publication in the French language.
language
FBcv:0000252
French
Publication in the French language.
FBC:MMC
Publication in the German language.
language
FBcv:0000253
German
Publication in the German language.
FBC:MMC
Publication in the Greek language.
language
FBcv:0000254
Greek
Publication in the Greek language.
FBC:MMC
Publication in the Hebrew language.
language
FBcv:0000255
Hebrew
Publication in the Hebrew language.
FBC:MMC
Publication in the Hungarian language.
language
FBcv:0000256
Hungarian
Publication in the Hungarian language.
FBC:MMC
Publication in the Icelandic language.
language
FBcv:0000257
Icelandic
Publication in the Icelandic language.
FBC:MMC
Publication in the Indonesian language.
language
FBcv:0000258
Indonesian
Publication in the Indonesian language.
FBC:MMC
Publication in the Italian language.
language
FBcv:0000259
Italian
Publication in the Italian language.
FBC:MMC
Publication in the Japanese language.
language
FBcv:0000260
Japanese
Publication in the Japanese language.
FBC:MMC
Publication in the Jugoslavian language.
language
FBcv:0000261
Jugoslavian
Publication in the Jugoslavian language.
FBC:MMC
Publication in the Korean language.
language
FBcv:0000262
Korean
Publication in the Korean language.
FBC:MMC
Publication in the Latin language.
language
FBcv:0000263
Latin
Publication in the Latin language.
FBC:MMC
Publication in the Latvian language.
language
FBcv:0000264
Latvian
Publication in the Latvian language.
FBC:MMC
Publication in the Lithuanian language.
language
FBcv:0000265
Lithuanian
Publication in the Lithuanian language.
FBC:MMC
Publication in the Malay language.
language
FBcv:0000266
Malay
Publication in the Malay language.
FBC:MMC
Publication in the Malayalam language.
language
FBcv:0000267
Malayalam
Publication in the Malayalam language.
FBC:MMC
Publication in the Norwegian language.
language
FBcv:0000268
Norwegian
Publication in the Norwegian language.
FBC:MMC
Publication in the Polish language.
language
FBcv:0000269
Polish
Publication in the Polish language.
FBC:MMC
Publication in the Portuguese language.
language
FBcv:0000270
Portuguese
Publication in the Portuguese language.
FBC:MMC
Publication in the Serbo-Croat (Roman) language.
language
FBcv:0000271
Serbo-Croat(Roman)
Publication in the Serbo-Croat (Roman) language.
FBC:MMC
Publication in the Roman language.
language
FBcv:0000272
Romanian
Publication in the Roman language.
FBC:MMC
Publication in the Russian language.
language
FBcv:0000273
Russian
Publication in the Russian language.
FBC:MMC
Publication in the Serbo-Croat language.
language
FBcv:0000274
Serbo-Croat
Publication in the Serbo-Croat language.
FBC:MMC
Publication in the Slovak language.
language
FBcv:0000275
Slovak
Publication in the Slovak language.
FBC:MMC
Publication in the Slovenian language.
language
FBcv:0000276
Slovenian
Publication in the Slovenian language.
FBC:MMC
Publication in the Spanish language.
language
FBcv:0000277
Spanish
Publication in the Spanish language.
FBC:MMC
Publication in the Swedish language.
language
FBcv:0000278
Swedish
Publication in the Swedish language.
FBC:MMC
Publication in the Turkish language.
language
FBcv:0000279
Turkish
Publication in the Turkish language.
FBC:MMC
Publication in the Ukrainian language.
language
FBcv:0000280
Ukrainian
Publication in the Ukrainian language.
FBC:MMC
Publication in the Yiddish language.
language
FBcv:0000281
Yiddish
Publication in the Yiddish language.
FBC:MMC
Rank that describes the usefulness of mutants according to their phenotype.
scorability
FBcv:0000282
mutant scorability rank
Rank that describes the usefulness of mutants according to their phenotype.
FBC:MMC
The RK1 rank describes mutants that are easily scored.
scorability
FBcv:0000283
RK1
The RK1 rank describes mutants that are easily scored.
FlyBase:FBrf0066905
The RK2 rank describes mutants that are usable but less convenient.
scorability
FBcv:0000284
RK2
The RK2 rank describes mutants that are usable but less convenient.
FlyBase:FBrf0066905
The RK3 rank describes mutants that are of limited usefulness.
scorability
FBcv:0000285
RK3
The RK3 rank describes mutants that are of limited usefulness.
FlyBase:FBrf0066905
Term that describes the type of allele.
allele morphy class
allele_class
FBcv:0000286
allele class
Term that describes the type of allele.
FBC:MMC
An allele that either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
allele_class
FBcv:0000287
Loss of function alleles are generally, but not exclusively, recessive. At haplo-insufficient loci (loci that require two copies for normal function), loss of function alleles can be dominant.
loss of function allele
An allele that either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
FlyBase:FBrf0049147
An allele inferred to completely lack function from the observation that addition of extra copies in the genome has no effect on the phenotype. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
allele_class
FBcv:0000288
amorphic allele - genetic evidence
An allele inferred to completely lack function from the observation that addition of extra copies in the genome has no effect on the phenotype. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
FlyBase:FBrf0002371
FlyBase:FBrf0049147
Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy)).
allele_class
FBcv:0000289
hypomorphic allele - genetic evidence
Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy)).
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
allele_class
FBcv:0000290
Gain of function alleles are generally dominant. But not all dominant alleles are gain of function alleles.
gain of function allele
An allele that either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
FlyBase:FBrf0049147
An allele that is inferred to make a gene product with a novel function or expression pattern compared to wild-type based on the evidence that the phenotype is unaffected by extra or fewer doses of the wild-type gene.
allele_class
FBcv:0000291
neomorphic allele - genetic evidence
An allele that is inferred to make a gene product with a novel function or expression pattern compared to wild-type based on the evidence that the phenotype is unaffected by extra or fewer doses of the wild-type gene.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele.
allele_class
FBcv:0000292
antimorphic allele - genetic evidence
An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy).
allele_class
FBcv:0000293
hypermorphic allele - genetic evidence
An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy).
FlyBase:FBrf0002371
FlyBase:FBrf0049147
Allele that corresponds to the wild-type one.
allele_class
FBcv:0000294
wild-type allele
Allele that corresponds to the wild-type one.
FBC:MMC
Wild-type allele that can be distinguished from others.
allele_class
FBcv:0000295
wild-type generic
Wild-type allele that can be distinguished from others.
FBC:MMC
Wild-type allele that can only be distinguished from another one under special conditions.
allele_class
FBcv:0000296
isoallele
Wild-type allele that can only be distinguished from another one under special conditions.
FlyBase:FBrf0202435
FlyBase miscellaneous CV
FBcv:0000297
extracted wild-type chromosome 1
true
A phenotypic attribute is described as recessive when it is manifest only in individuals homozygous or hemizygous for the allele that causes that phenotype.
dominance_qualifier
FBcv:0000298
recessive
A phenotypic attribute is described as recessive when it is manifest only in individuals homozygous or hemizygous for the allele that causes that phenotype.
ISBN:978-0-8053-0316-2
A phenotypic attribute is described as dominant when it is manifest in individuals heterozygous for the allele that causes that phenotype.
dominance_qualifier
FBcv:0000299
dominant
A phenotypic attribute is described as dominant when it is manifest in individuals heterozygous for the allele that causes that phenotype.
ISBN:978-0-8053-0316-2
A phenotypic attribute is described as codominant when it is manifest in individuals carrying the allele that causes that phenotype, irrespective of the homologous allele.
dominance_qualifier
FBcv:0000300
codominant
A phenotypic attribute is described as codominant when it is manifest in individuals carrying the allele that causes that phenotype, irrespective of the homologous allele.
ISBN:978-0-8053-0316-2
A phenotypic attribute is described as semidominant when individuals heterozygous for the allele show phenotypes part way between homozygotes for either allele.
dominance_qualifier
FBcv:0000301
semidominant
A phenotypic attribute is described as semidominant when individuals heterozygous for the allele show phenotypes part way between homozygotes for either allele.
ISBN:978-0-8053-0316-2
FlyBase miscellaneous CV
FBcv:0000302
extracted wild-type chromosome 2
true
FlyBase miscellaneous CV
FBcv:0000303
extracted wild-type chromosome 3
true
FlyBase miscellaneous CV
FBcv:0000304
extracted wild-type chromosome 4
true
FlyBase miscellaneous CV
FBcv:0000305
extracted wild-type chromosome Y
true
Expression is limited to one or other sex by virtue of the particular biology of that sex, rather than the sex-linkage of the genes underlying the attribute.
sex_qualifier
FBcv:0000306
May be used to qualify expression of phenotypes or of genes, transgenes etc.
sex limited
Expression is limited to one or other sex by virtue of the particular biology of that sex, rather than the sex-linkage of the genes underlying the attribute.
FlyBase:FBrf0075559
Expression is limited to males by virtue of the particular biology of males, rather than the sex-linkage of the gene(s) involved.
sex_qualifier
FBcv:0000307
May be used to qualify expression of phenotypes or of genes, transgenes etc.
male limited
Expression is limited to males by virtue of the particular biology of males, rather than the sex-linkage of the gene(s) involved.
FlyBase:FBrf0075559
Expression is limited to females by virtue of the particular biology of females, rather than the sex-linkage of the gene(s) involved.
sex_qualifier
FBcv:0000308
May be used to qualify expression of phenotypes or of genes, transgenes etc.
female limited
Expression is limited to females by virtue of the particular biology of females, rather than the sex-linkage of the gene(s) involved.
FlyBase:FBrf0075559
Phenotype expressed only under specific environmental conditions that do not induce the same defect in wild-type animals.
environmental_qualifier
conditional qualifier
FBcv:0000309
conditional
Phenotype expressed only under specific environmental conditions that do not induce the same defect in wild-type animals.
FBC:DOS
Phenotype only expressed in some subset of the temperature range within which wild-type animals are viable.
environmental_qualifier
FBcv:0000310
temperature conditional
Phenotype only expressed in some subset of the temperature range within which wild-type animals are viable.
FBC:DOS
Phenotype only expressed at high temperatures.
conditional - heat sensitive
conditional ts
hs
environmental_qualifier
FBcv:0000311
heat sensitive
Phenotype only expressed at high temperatures.
FBC:DOS
Phenotype only expressed at low temperatures.
conditional - cold sensitive
conditional cs
cs
environmental_qualifier
FBcv:0000312
cold sensitive
Phenotype only expressed at low temperatures.
FBC:DOS
Phenotype expressed only in the presence of some specific drug (CHEBI:23888) whose presence does not induce the same defect in wild-type animals.
environmental_qualifier
FBcv:0000313
drug conditional
Phenotype expressed only in the presence of some specific drug (CHEBI:23888) whose presence does not induce the same defect in wild-type animals.
FBC:DOS
Phenotype expressed only in the presence of RU486 (CHEBI:50692), also known as mifepristone.
conditional RU486
conditional mifepristone
environmental_qualifier
FBcv:0000314
RU486 conditional
Phenotype expressed only in the presence of RU486 (CHEBI:50692), also known as mifepristone.
FBC:DOS
Phenotype expressed only in the presence of tetracycline (CHEBI:27902).
conditional tetracycline
environmental_qualifier
FBcv:0000315
tetracycline conditional
Phenotype expressed only in the presence of tetracycline (CHEBI:27902).
FBC:DOS
Phenotype that is the partial or full transformation of one or more segments (FBbt:00000003) or segmental appendages from one identity to another. For example, in antennapedia an antenna is partially or fully transformed into a leg.
phenotypic_class
FBcv:0000316
homeotic
Phenotype that is the partial or full transformation of one or more segments (FBbt:00000003) or segmental appendages from one identity to another. For example, in antennapedia an antenna is partially or fully transformed into a leg.
FBC:DOS
FlyBase miscellaneous CV
FBcv:0000317
isogenic chromosome 1
true
FlyBase miscellaneous CV
FBcv:0000318
isogenic chromosome 2
true
Expression across a contiguous block of two or more segments of the blastoderm.
embryonic_pattern_qualifier
FBcv:0000319
gap expression pattern
Expression across a contiguous block of two or more segments of the blastoderm.
FBC:DOS
Expression in the terminal regions of the embryo/larva: the acron, telson and adjacent segments.
embryonic_pattern_qualifier
terminal
FBcv:0000320
terminal expression pattern
Expression in the terminal regions of the embryo/larva: the acron, telson and adjacent segments.
FBC:DOS
FlyBase miscellaneous CV
FBcv:0000321
isogenic chromosome 3
true
Expression in alternate segments of the blastoderm.
embryonic_pattern_qualifier
FBcv:0000322
pair rule expression pattern
Expression in alternate segments of the blastoderm.
FBC:DOS
Qualifier that describes an expression pattern of a segment polarity gene. Expression is observed in a specific location in each segment.
embryonic_pattern_qualifier
FBcv:0000323
segment polarity expression pattern
Qualifier that describes an expression pattern of a segment polarity gene. Expression is observed in a specific location in each segment.
FBC:MMC
Phenotype that is a defect in dorsal/ventral axis specification (GO:0009950). 'dorsal/ventral axis specification' is defined as: 'The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.'
phenotypic_class
dorsal-ventral polarity
FBcv:0000324
dorsal/ventral axis specification defective
Phenotype that is a defect in dorsal/ventral axis specification (GO:0009950). 'dorsal/ventral axis specification' is defined as: 'The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.'
FBC:DOS
GOC:dph
GOC:go_curators
GOC:tb
dorsal-ventral polarity
FBC:DOS
A phenotype that is an expansion of the developing embryonic nervous system at the expense of developing ventral epidermis.
djs93
2011-09-13T02:42:10Z
phenotypic_class
FBcv:0000325
Typically this is caused by and expansion of the population of neuroblasts at the expense of prospective epidermis, both of which originate in the ventral ectoderm.
neurogenic phenotype
A phenotype that is an expansion of the developing embryonic nervous system at the expense of developing ventral epidermis.
FlyBase:FBrf0040185
FlyBase miscellaneous CV
FBcv:0000326
isogenic chromosome 4
true
FlyBase miscellaneous CV
FBcv:0000327
P-element transposase source for transposable element mutagenesis
true
FlyBase miscellaneous CV
FBcv:0000328
hobo transposase source for transposable element mutagenesis
true
FlyBase miscellaneous CV
FBcv:0000329
piggyBac transposase source for transposable element mutagenesis
true
FlyBase miscellaneous CV
FBcv:0000330
minos transposase source for transposable element mutagenesis
true
FBcv:0000176
PATO:0001774
temporal_qualifier
FBcv:0000331
This term has been obsoleted because there are new terms to replace it [FBC:MMC]. mc161027
polyphasic
true
Qualifier that relates the expression of a phenotype to the sex of the individual.
sex qualifier
sex_qualifier
FBcv:0000332
sex
Qualifier that relates the expression of a phenotype to the sex of the individual.
FBC:MMC
sex qualifier
FBC:DOS
Expressed in males.
sex_qualifier
FBcv:0000333
This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in males.
male
Expressed in males.
FBC:DOS
Expressed in females.
sex_qualifier
FBcv:0000334
This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in females.
female
Expressed in females.
FBC:DOS
A clone of germline cells that share a genotype.
germ-line clone
clone_qualifier
FBcv:0000335
germline clone
A clone of germline cells that share a genotype.
FBC:DOS
A clone of somatic cells that share a genotype that is different from the genotype of the animal in which it resides and from which it is derived.
clone_qualifier
FBcv:0000336
somatic clone
A clone of somatic cells that share a genotype that is different from the genotype of the animal in which it resides and from which it is derived.
FBC:DOS
FlyBase miscellaneous CV
FBcv:0000337
P-element ammunition for transposable element mutagenesis
true
FlyBase miscellaneous CV
FBcv:0000338
hobo ammunition for transposable element mutagenesis
true
FBcv:0000811
extent
FBcv:0000339
DEPRECATION WARNING: This term has been obsoleted as 'fully' is assumed in the absence of use of 'partially'. mc151118
fully
true
Incomplete penetrance or expressivity of a phenotype or incomplete suppression of a phenotype.
extent
FBcv:0000340
Note on usage: This qualifier should not be used in combination with lethal, viable, sterile or fertile. For these cases, terms of the form semi-X should be used instead.
partially
Incomplete penetrance or expressivity of a phenotype or incomplete suppression of a phenotype.
FBC:DOS
FBcv:0000811
intensity_qualifier
FBcv:0000341
This term has been obsoleted as it should be assumed a phenotype is good, unless it is said otherwise, by using other qualifiers. mc151118
good
true
Qualifier that describes a phenotype that has poor penetrance or expressivity.
intensity_qualifier
FBcv:0000342
poor
Qualifier that describes a phenotype that has poor penetrance or expressivity.
FBC:MMC
Qualifier that describes a phenotype that has reduced penetrance or expressivity when compared to wild-type.
intensity_qualifier
FBcv:0000343
reduced
Qualifier that describes a phenotype that has reduced penetrance or expressivity when compared to wild-type.
FBC:MMC
Qualifier that describes an electrophoretic migration of a gene product that is slower than the wild-type.
PATO:0000304
intensity_qualifier
FBcv:0000344
slow
Qualifier that describes an electrophoretic migration of a gene product that is slower than the wild-type.
FBC:MMC
Qualifier that describes an electrophoretic migration of a gene product that is intermediate in speed compared to the wild-type.
PATO:0000303
intensity_qualifier
FBcv:0000345
fast
Qualifier that describes an electrophoretic migration of a gene product that is intermediate in speed compared to the wild-type.
FBC:MMC
Qualifier that describes a phenotype that is intermediate in speed compared to the wild-type.
intensity_qualifier
FBcv:0000346
This qualifier can be used to describe an electrophoretic migration of a gene product that is intermediate in speed compared to the wild-type.
intermediate
Qualifier that describes a phenotype that is intermediate in speed compared to the wild-type.
FBC:MMC
phenotypic_class
FBcv:0000347
phenotypic class
The canonical phenotype of a wild-type Drosophilid.
phenotypic_class
FBcv:0000348
wild-type
The canonical phenotype of a wild-type Drosophilid.
FBC:DOS
A phenotype that is survival to mature adulthood, where mature is defined as after adult stage A3 (FBdv:00006012).
phenotypic_class
FBcv:0000349
Note, this term should not be used with the qualifier 'partially'. Use semi-viable or semi-lethal instead.
viable
A phenotype that is survival to mature adulthood, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
A phenotype of a population that is the death of some significant proportion of animals in that population, but less that half, prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
semi-viable
phenotypic_class
FBcv:0000350
partially lethal - majority live
A phenotype of a population that is the death of some significant proportion of animals in that population, but less that half, prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
phenotypic_class
FBcv:0000351
Note on usage: lethal is appropriate in cases where escaper adults are very rare. The lethal phase prior to becoming a mature adult may be further specified using children terms which specify stage.
lethal
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
FBC:KM
A phenotype of a population that is the death of a majority of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
semi-lethal
phenotypic_class
FBcv:0000352
Stages during which there is significant death prior to mature adulthood can be indicated using one or more stage qualifiers.
partially lethal - majority die
A phenotype of a population that is the death of a majority of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
FBC:KM
FBC:NB
A phenotype that is a failure of mutant cells to survive.
phenotypic_class
FBcv:0000353
Typically, this phenotype is assayed in clones of cells.
cell lethal
A phenotype that is a failure of mutant cells to survive.
FBC:DOS
A post-embryonic, macroscopic, anatomical phenotype.
phenotypic_class
FBcv:0000354
visible
A post-embryonic, macroscopic, anatomical phenotype.
FBC:DOS
Phenotype that is a defect in eye color compared to wild-type.
eye colour defective
phenotypic_class
FBcv:0000355
eye color defective
Phenotype that is a defect in eye color compared to wild-type.
FBC:DOS
A phenotype that is a defect in body color compared to wild-type.
body colour defective
phenotypic_class
FBcv:0000356
body color defective
A phenotype that is a defect in body color compared to wild-type.
FBC:DOS
A phenotype that is a defect in the size of the whole body or some body part compared to wild-type.
phenotypic_class
FBcv:0000357
size defective
A phenotype that is a defect in the size of the whole body or some body part compared to wild-type.
FBC:DOS
Phenotype that is a decrease in body size compared to identically raised wild-type controls.
phenotypic_class
FBcv:0000358
small body
Phenotype that is a decrease in body size compared to identically raised wild-type controls.
FBC:DOS
Phenotype that is a decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth - there may be fewer cells in an otherwise normal volume of tissue.
reduced cell number
phenotypic_class
FBcv:0000359
decreased cell number
Phenotype that is a decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth - there may be fewer cells in an otherwise normal volume of tissue.
FBC:DOS
Phenotype that is a decrease in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth of a tissue - there may be more cells in an otherwise normal volume of tissue.
reduced cell size
phenotypic_class
FBcv:0000360
Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells.
decreased cell size
Phenotype that is a decrease in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth of a tissue - there may be more cells in an otherwise normal volume of tissue.
FBC:DOS
Phenotype that is an increase in body size compared to identically raised wild-type controls.
phenotypic_class
FBcv:0000361
large body
Phenotype that is an increase in body size compared to identically raised wild-type controls.
FBC:DOS
Phenotype that is an increase in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type.
phenotypic_class
FBcv:0000362
This phenotype is not necessarily accompanied by overgrowth of a tissue - there may be more cells in an otherwise normal volume of tissue. It is not necessarily due to an increase in cell growth -it may be the result of an increase in the division rate at normal growth rates. It may not even be due to an increase in the cell division rate - a reduced rate of cell death while the division rate is normal could also achieve it.
increased cell number
Phenotype that is an increase in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is an increase in the size of cells compared to wild-type.
phenotypic_class
FBcv:0000363
May be due to an increase in the cell growth rate or to a reduced rate of cell division along with a normal rate of cell growth.
increased cell size
Phenotype that is an increase in the size of cells compared to wild-type.
FBC:DOS
A phenotype that is the inability to produce a zygote.
phenotypic_class
FBcv:0000364
The cause of sterility may be physical or behavioral. Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead.
sterile
A phenotype that is the inability to produce a zygote.
FBC:DOS
A phenotype that is a reduction in the proportion of fertilized eggs produced to below 50% of wild-type.
phenotypic_class
FBcv:0000365
semi-sterile
A phenotype that is a reduction in the proportion of fertilized eggs produced to below 50% of wild-type.
FBC:DOS
A phenotype that is the inability of females to mate and produce fertilized offspring.
phenotypic_class
FBcv:0000366
The cause of sterility may be physical or behavioral. Note: this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead.
female sterile
A phenotype that is the inability of females to mate and produce fertilized offspring.
FBC:DOS
A phenotype that is a reduction in the proportion of fertilized eggs produced by females to below 50% of wild-type.
phenotypic_class
FBcv:0000367
female semi-sterile
A phenotype that is a reduction in the proportion of fertilized eggs produced by females to below 50% of wild-type.
FBC:DOS
A phenotype of female sterility due to defects in the female germline.
female sterile germ-line-dependent
phenotypic_class
FBcv:0000368
female sterile germline-dependent
A phenotype of female sterility due to defects in the female germline.
FBC:DOS
A phenotype of female sterility due to defects in somatic cells of the ovary (FBbt:00006030), or of the products of these cells (such as eggshell).
phenotypic_class
FBcv:0000369
female sterile soma-dependent
A phenotype of female sterility due to defects in somatic cells of the ovary (FBbt:00006030), or of the products of these cells (such as eggshell).
FBC:DOS
A phenotype that is the inability of males to mate and produce fertilized offspring.
phenotypic_class
FBcv:0000370
The cause of sterility may be physical or behavioral. Note - this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead.
male sterile
A phenotype that is the inability of males to mate and produce fertilized offspring.
FBC:DOS
A phenotype that is a reduction in the proportion of fertilized eggs produced by males to below 50% of wild-type.
phenotypic_class
FBcv:0000371
male semi-sterile
A phenotype that is a reduction in the proportion of fertilized eggs produced by males to below 50% of wild-type.
FBC:DOS
A phenotype of male sterility due to defects in the male germline.
male sterile germ-line-dependent
phenotypic_class
FBcv:0000372
male sterile germline-dependent
A phenotype of male sterility due to defects in the male germline.
FBC:DOS
A phenotype of male sterility due to defects in somatic cells of the testis (FBbt:00006031) or of the products of these cells.
phenotypic_class
FBcv:0000373
male sterile soma-dependent
A phenotype of male sterility due to defects in somatic cells of the testis (FBbt:00006031) or of the products of these cells.
FBC:DOS
A phenotype that is the ability to mate and as a result produce fertilized eggs.
phenotypic_class
FBcv:0000374
Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead.
fertile
A phenotype that is the ability to mate and as a result produce fertilized eggs.
FBC:DOS
Phenotype that is a reduction in the proportion of fertilized eggs produced, but only to > 50% of wild-type.
phenotypic_class
FBcv:0000375
semi-fertile
Phenotype that is a reduction in the proportion of fertilized eggs produced, but only to > 50% of wild-type.
FBC:DOS
A phenotype that is the ability of males to mate and as a result produce fertilized eggs.
phenotypic_class
FBcv:0000376
Note - this term should not be used with the qualifier 'partially' - use male semi-sterile or male semi-fertile instead.
male fertile
A phenotype that is the ability of males to mate and as a result produce fertilized eggs.
FBC:DOS
A phenotype that is the ability of females to mate and as a result produce fertilized eggs.
phenotypic_class
FBcv:0000377
Note - this term should not be used with the qualifier 'partially' - use female semi-sterile or female semi-fertile instead.
female fertile
A phenotype that is the ability of females to mate and as a result produce fertilized eggs.
FBC:DOS
A phenotype in which all offspring are sterile. Typically, this is due to maternal effect sterility resulting from defects in pole cell development.
phenotypic_class
FBcv:0000378
grandchildless
A phenotype in which all offspring are sterile. Typically, this is due to maternal effect sterility resulting from defects in pole cell development.
ISBN:978-0-87969-321-3
Genotype g1 is an enhancer of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is greater than that caused by g2 alone.
phenotypic_class
FBcv:0000379
Typically, g2 is a chromosomal aberration or an insertion.
enhancer of variegation
Genotype g1 is an enhancer of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is greater than that caused by g2 alone.
FBC:DOS
Genotype g1 is a non-enhancer of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not greater than that caused by g2 alone.
phenotypic_class
FBcv:0000380
non-enhancer of variegation
Genotype g1 is a non-enhancer of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not greater than that caused by g2 alone.
FBC:DOS
Genotype g1 is a suppressor of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is less than that caused by to g2 alone.
phenotypic_class
FBcv:0000381
Typically, g2 is a chromosomal aberration or an insertion.
suppressor of variegation
Genotype g1 is a suppressor of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is less than that caused by to g2 alone.
FBC:DOS
Genotype g1 is a non-suppressor of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not less than that caused by g2 alone.
phenotypic_class
FBcv:0000382
non-suppressor of variegation
Genotype g1 is a non-suppressor of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not less than that caused by g2 alone.
FBC:DOS
A phenotype that is the inability to synthesize some organic compound that can be synthesized by wild-type animals, and that is required for normal growth and/or development.
phenotypic_class
FBcv:0000383
auxotroph
A phenotype that is the inability to synthesize some organic compound that can be synthesized by wild-type animals, and that is required for normal growth and/or development.
http://en.wikipedia.org/wiki/Auxotrophic
Phenotype that is a defect in aging (GO:0007568). 'aging' is defined as: 'A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).'
phenotypic_class
FBcv:0000384
aging defective
Phenotype that is a defect in aging (GO:0007568). 'aging' is defined as: 'A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).'
GOC:PO_curators
Phenotype that is a shorter adult life-span than wild-type.
increased adult mortality
phenotypic_class
FBcv:0000385
short lived
Phenotype that is a shorter adult life-span than wild-type.
FBC:DOS
Phenotype that is a longer adult life-span than wild-type.
phenotypic_class
FBcv:0000386
long lived
Phenotype that is a longer adult life-span than wild-type.
FBC:DOS
Phenotype that is a defect in behavior (GO:0007610). 'behavior' is defined as: 'The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.'
behaviour defective
behavioural
phenotypic_class
behavioral
FBcv:0000387
behavior defective
Phenotype that is a defect in behavior (GO:0007610). 'behavior' is defined as: 'The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.'
GOC:ems
GOC:jl
ISBN:0395448956
PMID:20160973
Phenotype that is a change in the strong tendency, seen in wild-type Drosophila melanogaster, to climb - a behavior otherwise known as negative gravitaxis (GO:0048060 ; movement away from the source of gravity).
phenotypic_class
geotaxis behaviour defective
gravitaxis behavior defective
FBcv:0000388
Note, this term should not be used when flies have climbing defects purely as a consequence of locomotion defects, use 'locomotor behavior defective' instead.
gravitaxis defective
Phenotype that is a change in the strong tendency, seen in wild-type Drosophila melanogaster, to climb - a behavior otherwise known as negative gravitaxis (GO:0048060 ; movement away from the source of gravity).
FBC:DOS
Phenotype that is a disposition to paralysis under conditions that do not cause paralysis in a wild-type animal. Paralysis is defined as an inability to exhibit `multicellular organismal movement` (GO:0050879)
phenotypic_class
FBcv:0000389
paralytic
Phenotype that is a disposition to paralysis under conditions that do not cause paralysis in a wild-type animal. Paralysis is defined as an inability to exhibit `multicellular organismal movement` (GO:0050879)
FBC:DOS
A phenotype consisting of decreased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type.
phenotypic_class
FBcv:0000390
hypoactive
A phenotype consisting of decreased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type.
FBC:DOS
A phenotype exhibited following mechanical shock and consisting of a brief period of intense, uncoordinated motor activity (legs and wings flailing, abdomen coiling) followed by a prolonged period of paralysis.
phenotypic_class
easily shocked
FBcv:0000391
bang sensitive
A phenotype exhibited following mechanical shock and consisting of a brief period of intense, uncoordinated motor activity (legs and wings flailing, abdomen coiling) followed by a prolonged period of paralysis.
FlyBase:FBrf0022877
easily shocked
FlyBase:FBrf0022877
A phenotype consisting of increased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type.
phenotypic_class
FBcv:0000392
hyperactive
A phenotype consisting of increased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type.
FBC:DOS
Phenotype that is a defect in response to pain (GO:0048265). 'response to pain' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.'
phenotypic_class
FBcv:0000393
pain response defective
Phenotype that is a defect in response to pain (GO:0048265). 'response to pain' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.'
FBC:DOS
GOC:jid
PMID:10203867
PMID:12723742
PMID:12843304
Wikipedia:Pain
Phenotype that is a defect in circadian rhythm (GO:0007623). 'circadian rhythm' is defined as: 'Any biological process in an organism that recurs with a regularity of approximately 24 hours.'
phenotypic_class
FBcv:0000394
circadian rhythm defective
Phenotype that is a defect in circadian rhythm (GO:0007623). 'circadian rhythm' is defined as: 'Any biological process in an organism that recurs with a regularity of approximately 24 hours.'
FBC:DOS
GOC:bf
GOC:go_curators
Phenotype that is a defect in locomotor rhythm (GO:0045475). 'locomotor rhythm' is defined as: 'The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.'
phenotypic_class
FBcv:0000395
locomotor rhythm defective
Phenotype that is a defect in locomotor rhythm (GO:0045475). 'locomotor rhythm' is defined as: 'The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.'
FBC:DOS
GOC:go_curators
Phenotype that is a defect in eclosion rhythm (GO:0008062). 'eclosion rhythm' is defined as: 'The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.'
phenotypic_class
FBcv:0000396
eclosion rhythm defective
Phenotype that is a defect in eclosion rhythm (GO:0008062). 'eclosion rhythm' is defined as: 'The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.'
FBC:DOS
PMID:11715043
Phenotype that is a defect in learning (GO:0007612). 'learning' is defined as: 'Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.'
phenotypic_class
FBcv:0000397
learning defective
Phenotype that is a defect in learning (GO:0007612). 'learning' is defined as: 'Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.'
FBC:DOS
ISBN:0582227089
ISBN:0721662544
Phenotype that is a defect in memory (GO:0007613). 'memory' is defined as: 'The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).'
phenotypic_class
FBcv:0000398
memory defective
Phenotype that is a defect in memory (GO:0007613). 'memory' is defined as: 'The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).'
FBC:DOS
GOC:curators
ISBN:0582227089
Phenotype that is a defect in courtship behavior (GO:0007619). 'courtship behavior' is defined as: 'The behavior of an organism for the purpose of attracting sexual partners.'
phenotypic_class
FBcv:0000399
courtship behavior defective
Phenotype that is a defect in courtship behavior (GO:0007619). 'courtship behavior' is defined as: 'The behavior of an organism for the purpose of attracting sexual partners.'
FBC:DOS
GOC:ai
GOC:dph
Phenotype that is a defect in mating (GO:0007618). 'mating' is defined as: 'The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.'
phenotypic_class
FBcv:0000400
mating defective
Phenotype that is a defect in mating (GO:0007618). 'mating' is defined as: 'The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.'
FBC:DOS
GOC:jl
ISBN:0387520546
Phenotype that is a defect in circadian mating behavior (GO:0035648). 'circadian mating behavior' is defined as: 'The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.'
phenotypic_class
FBcv:0000401
mating rhythm defective
Phenotype that is a defect in circadian mating behavior (GO:0035648). 'circadian mating behavior' is defined as: 'The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.'
FBC:DOS
GOC:bf
GOC:dos
PMID:11470898
PMID:17276917
Phenotype that is a defect in male courtship behavior, veined wing generated song production (GO:0045433). This is defined as 'The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.'
singing defective
song production defective
phenotypic_class
FBcv:0000402
song defective
Phenotype that is a defect in male courtship behavior, veined wing generated song production (GO:0045433). This is defined as 'The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.'
FBC:DOS
GOC:mtg_sensu
PMID:11092827
singing defective
FBC:SM
song production defective
FBC:SM
Phenotype that is a defect in chemosensory behavior (GO:0007635). 'chemosensory behavior' is defined as: 'Behavior that is dependent upon the sensation of chemicals.'.'
chemosensitive behaviour defective
phenotypic_class
FBcv:0000403
chemosensitive behavior defective
Phenotype that is a defect in chemosensory behavior (GO:0007635). 'chemosensory behavior' is defined as: 'Behavior that is dependent upon the sensation of chemicals.'.'
FBC:DOS
GOC:go_curators
Phenotype that is a defect in sensory perception of smell (GO:0007608). 'sensory perception of smell' is defined as: 'The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.'
olfaction defective
phenotypic_class
FBcv:0000404
smell perception defective
Phenotype that is a defect in sensory perception of smell (GO:0007608). 'sensory perception of smell' is defined as: 'The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.'
FBC:DOS
GOC:ai
Phenotype that is a defect in sensory perception of taste (GO:0050909). 'sensory perception of taste' is defined as: 'The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.'
gustation defective
taste defective
phenotypic_class
FBcv:0000405
taste perception defective
Phenotype that is a defect in sensory perception of taste (GO:0050909). 'sensory perception of taste' is defined as: 'The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.'
FBC:DOS
GOC:ai
Phenotype that is a failure to exhibit proboscis extension reflex in response to a sugar stimulus via taste sensilla on the tarsus.
phenotypic_class
FBcv:0000406
tarsal response defective
Phenotype that is a failure to exhibit proboscis extension reflex in response to a sugar stimulus via taste sensilla on the tarsus.
FBC:DOS
Phenotype that is a defect in sensory perception of sound (GO:0007605). 'sensory perception of sound' is defined as: 'The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.'
phenotypic_class
auditory system defective
FBcv:0000407
auditory perception defective
Phenotype that is a defect in sensory perception of sound (GO:0007605). 'sensory perception of sound' is defined as: 'The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.'
FBC:DOS
GOC:ai
Phenotype that is a defect in response to stress (GO:0006950). 'response to stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).'
environmental stress response defective
phenotypic_class
FBcv:0000408
stress response defective
Phenotype that is a defect in response to stress (GO:0006950). 'response to stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).'
FBC:DOS
GOC:mah
Phenotype that is a defect in response to osmotic stress (GO:0006970). 'response to osmotic stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.'
phenotypic_class
FBcv:0000409
osmotic stress response defective
Phenotype that is a defect in response to osmotic stress (GO:0006970). 'response to osmotic stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.'
FBC:DOS
GOC:jl
Phenotype that is a defect in response to heat (GO:0009408). 'response to heat' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.'
phenotypic_class
FBcv:0000410
heat stress response defective
Phenotype that is a defect in response to heat (GO:0009408). 'response to heat' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.'
FBC:DOS
GOC:lr
Phenotype that is a defect in visual behavior (GO:0007632). 'visual behavior' is defined as: 'The behavior of an organism in response to a visual stimulus.'
visual behaviour defective
phenotypic_class
FBcv:0000411
visual behavior defective
Phenotype that is a defect in visual behavior (GO:0007632). 'visual behavior' is defined as: 'The behavior of an organism in response to a visual stimulus.'
FBC:DOS
GOC:jid
GOC:pr
Phenotype that is a defect in optomotor response: a motor response during flight or walking that serves to stabilize both image formation on the retina and locomotor course.
optomotor behaviour defective
phenotypic_class
FBcv:0000412
optomotor response defective
Phenotype that is a defect in optomotor response: a motor response during flight or walking that serves to stabilize both image formation on the retina and locomotor course.
FBC:DOS
Phenotype that is a defect in phototaxis (GO:0042331). 'phototaxis' is defined as: 'The directed movement of a motile cell or organism in response to light.'
phenotypic_class
phototaxis behaviour defective
FBcv:0000413
phototaxis defective
Phenotype that is a defect in phototaxis (GO:0042331). 'phototaxis' is defined as: 'The directed movement of a motile cell or organism in response to light.'
FBC:DOS
GOC:jl
ISBN:0192800981
Phenotype that is a defect in locomotory behavior (GO:0007626). 'locomotory behavior' is defined as: 'The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.'
locomotor behaviour defective
phenotypic_class
FBcv:0000414
locomotor behavior defective
Phenotype that is a defect in locomotory behavior (GO:0007626). 'locomotory behavior' is defined as: 'The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.'
FBC:DOS
GOC:dph
Phenotype that is a reduced ability to jump or a reduced jump response. This may be due to neurological or muscular defects.
phenotypic_class
FBcv:0000415
jumping defective
Phenotype that is a reduced ability to jump or a reduced jump response. This may be due to neurological or muscular defects.
FBC:DOS
Phenotype that is a lack of normal co-ordination in locomotor activity.
phenotypic_class
FBcv:0000416
uncoordinated
Phenotype that is a lack of normal co-ordination in locomotor activity.
FBC:DOS
Phenotype that is a defect in flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'
flight behaviour defective
phenotypic_class
FBcv:0000417
This term is agnostic as to the causes of defects in flight. An animal's flight may be defective for mechanical, behavioral or sensory reasons.
flight defective
Phenotype that is a defect in flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'
FBC:DOS
GOC:dph
Phenotype that is the absence of flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'
phenotypic_class
FBcv:0000418
This term is agnostic as to the causes of flightlessness. An animal may be flightless for mechanical or behavioral reasons.
flightless
Phenotype that is the absence of flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'
FBC:DOS
GOC:dph
Phenotype that is a defect in feeding behavior (GO:0007631). 'feeding behavior' is defined as: 'Behavior associated with the intake of food.'
feeding behaviour defective
phenotypic_class
FBcv:0000419
feeding behavior defective
Phenotype that is a defect in feeding behavior (GO:0007631). 'feeding behavior' is defined as: 'Behavior associated with the intake of food.'
FBC:DOS
GOC:mah
Phenotype that is a defect in grooming behavior (GO:0007625). 'grooming behavior' is defined as: 'The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.'
grooming behaviour defective
phenotypic_class
FBcv:0000420
grooming behavior defective
Phenotype that is a defect in grooming behavior (GO:0007625). 'grooming behavior' is defined as: 'The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.'
FBC:DOS
GOC:jl
GOC:pr
Phenotype that is reduction in or loss of a stereotypical behavioral response to touch.
touch sensitivity defective
phenotypic_class
FBcv:0000421
This phenotype is commonly assayed by scoring larval avoidance responses following stroking of the thoracic segments (see Kernan et al., 1994). On its own, this is not sufficient evidence for a defect in sensory perception of touch, as motor defects can also cause this phenotype.
touch response defective
Phenotype that is reduction in or loss of a stereotypical behavioral response to touch.
FlyBase:FBrf0073546
Phenotype that is a defect in entrainment of circadian clock by photoperiod (GO:0043153), which is defined as: 'The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).'
phenotypic_class
FBcv:0000422
photoperiod response variant
Phenotype that is a defect in entrainment of circadian clock by photoperiod (GO:0043153), which is defined as: 'The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).'
FBC:DOS
GOC:jl
Phenotype that is a defect in DNA repair (GO:0006281). 'DNA repair' is defined as: 'The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.'
phenotypic_class
FBcv:0000423
DNA repair defective
Phenotype that is a defect in DNA repair (GO:0006281). 'DNA repair' is defined as: 'The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.'
FBC:DOS
PMID:11563486
Phenotype that is a change in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type. This may be due to effects on the regulation of cell death (GO:0010941) or in cell death (GO:0008219) pathways themselves.
apoptosis defective
pcd defective
programmed cell death defective
phenotypic_class
FBcv:0000424
cell death defective
Phenotype that is a change in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type. This may be due to effects on the regulation of cell death (GO:0010941) or in cell death (GO:0008219) pathways themselves.
FBC:DOS
Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
pcd increase
programmed cell death increase
phenotypic_class
FBcv:0000425
increased cell death
Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is a decrease in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
pcd decrease
programmed cell death decrease
phenotypic_class
FBcv:0000426
decreased cell death
Phenotype that is a decrease in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is a defect in cell growth (GO:0016049). 'cell growth' is defined as: 'The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.'
phenotypic_class
FBcv:0000427
Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells.
cell growth defective
Phenotype that is a defect in cell growth (GO:0016049). 'cell growth' is defined as: 'The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.'
FBC:DOS
GOC:ai
Phenotype that is a defect in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type.
phenotypic_class
FBcv:0000428
cell size defective
Phenotype that is a defect in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is a defect in the shape (PATO:0000052) of some cell compared to wild-type.
phenotypic_class
FBcv:0000429
cell shape defective
Phenotype that is a defect in the shape (PATO:0000052) of some cell compared to wild-type.
FBC:DOS
Phenotype that is a defect in the asymmetric distribution of components within a cell. For example an epithelial cell is 'cell polarity defective' if it lacks the normal asymmetric distribution of proteins or cell components such as junctions or villi along its apical-basal axis.
phenotypic_class
FBcv:0000430
cell polarity defective
Phenotype that is a defect in the asymmetric distribution of components within a cell. For example an epithelial cell is 'cell polarity defective' if it lacks the normal asymmetric distribution of proteins or cell components such as junctions or villi along its apical-basal axis.
FBC:DOS
Phenotype that is a defect in meiotic cell cycle (GO:0051321). 'meiotic cell cycle' is defined as: 'Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.'
phenotypic_class
meiotic
FBcv:0000431
meiotic cell cycle defective
Phenotype that is a defect in meiotic cell cycle (GO:0051321). 'meiotic cell cycle' is defined as: 'Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.'
FBC:DOS
GOC:ai
Phenotype that is a defect in mitotic cell cycle (GO:0000278). 'mitotic cell cycle' is defined as: 'Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.'
phenotypic_class
mitotic
FBcv:0000432
mitotic cell cycle defective
Phenotype that is a defect in mitotic cell cycle (GO:0000278). 'mitotic cell cycle' is defined as: 'Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.'
FBC:DOS
GOC:mah
ISBN:0815316194
Reactome:69278
Phenotype that is a defect in cytokinesis (GO:0000910). 'cytokinesis' is defined as: 'The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.'
phenotypic_class
FBcv:0000433
cytokinesis defective
Phenotype that is a defect in cytokinesis (GO:0000910). 'cytokinesis' is defined as: 'The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.'
FBC:DOS
GOC:mtg_cell_cycle
Phenotype that is a defect in the electrophysiological properties of some class of neurons, muscles or anatomical structure of the nervous system. Examples of these phenotypes at the neuron class level include defects in spontaneous or evoked excitatory junction potential. Examples at a more gross anatomical level include abnormal retinal electrophysiology (e.g.- measured by an electroretinogram).
phenotypic_class
FBcv:0000434
neurophysiology defective
Phenotype that is a defect in the electrophysiological properties of some class of neurons, muscles or anatomical structure of the nervous system. Examples of these phenotypes at the neuron class level include defects in spontaneous or evoked excitatory junction potential. Examples at a more gross anatomical level include abnormal retinal electrophysiology (e.g.- measured by an electroretinogram).
FBC:DOS
Phenotype that is a defect in nervous system (FBbt:00005093). 'nervous system' is defined as: 'All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.'
phenotypic_class
FBcv:0000435
neuroanatomy defective
Phenotype that is a defect in nervous system (FBbt:00005093). 'nervous system' is defined as: 'All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.'
FBC:DOS
FlyBase:FBrf0166419
Phenotype that is a defect in sex determination (GO:0007530). 'sex determination' is defined as: 'Any process that establishes and transmits the specification of sexual status of an individual organism.'
phenotypic_class
FBcv:0000436
sex-determination defective
Phenotype that is a defect in sex determination (GO:0007530). 'sex determination' is defined as: 'Any process that establishes and transmits the specification of sexual status of an individual organism.'
FBC:DOS
ISBN:0198506732
FBcv:0000436
phenotypic_class
FBcv:0000437
This term was obsoleted because it was felt that the evidence provided in papers is not enough to annotate with this term. mc161014
dosage compensation defective
true
Phenotype that is a difference in electrophoretic migration of a gene product compared to wild-type.
phenotypic_class
FBcv:0000438
electrophoretic variant
Phenotype that is a difference in electrophoretic migration of a gene product compared to wild-type.
FBC:DOS
Phenotype that is a decreased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
phenotypic_class
FBcv:0000439
chemical resistant
Phenotype that is a decreased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
FBC:DOS
Phenotype that is an increased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
phenotypic_class
FBcv:0000440
chemical sensitive
Phenotype that is an increased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
FBC:DOS
Phenotype that is a decreased tendency for radiation exposure to cause toxic effects.
phenotypic_class
FBcv:0000441
radiation resistant
Phenotype that is a decreased tendency for radiation exposure to cause toxic effects.
FBC:DOS
Phenotype that is an increased tendency for radiation exposure to cause toxic effects.
phenotypic_class
FBcv:0000442
radiation sensitive
Phenotype that is an increased tendency for radiation exposure to cause toxic effects.
FBC:DOS
Dominant phenotype consisting of short slender bristles and delayed development. Homozygotes are cell lethal.
phenotypic_class
FBcv:0000443
The phenotype may be a general result of mutations in essential components of the protein synthesis pathway, as a number of Minutes encode ribosomal proteins. In an animal that is heterozygous for a Minute mutation, cells with two wild-type alleles of the affected gene have a growth advantage. Many developmental studies take advantage of this fact to give somatic clones a growth advantage. The term 'Minute' should not be used to annotate the resulting phenotypes.
Minute
Dominant phenotype consisting of short slender bristles and delayed development. Homozygotes are cell lethal.
FlyBase:FBrf0066905
Phenotype that is an increase in size of a tissue or organ due to increased numbers of cells, where the affected tissue or organ maintains its normal form.
hyperplastic
phenotypic_class
FBcv:0000444
hyperplasia
Phenotype that is an increase in size of a tissue or organ due to increased numbers of cells, where the affected tissue or organ maintains its normal form.
ISBN:9780198506737
Phenotype that is characterized by the formation of abnormal masses of tissue (tumors) as the result of neoplasia.
phenotypic_class
FBcv:0000445
tumorigenic
Phenotype that is characterized by the formation of abnormal masses of tissue (tumors) as the result of neoplasia.
FBC:DOS
Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies.
melanotic 'tumor'
phenotypic_class
FBcv:0000446
Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immune response. While melanotic masses are commonly referred to as melanotic tumors in the historical literature, this is a misnomer as they are rarely neoplastic.
melanotic mass phenotype
Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies.
FlyBase:FBrf0094387
FlyBase:FBrf0194475
Phenotype characterized by closely associated necrosis and melanization.
phenotypic_class
FBcv:0000447
melanotic necrosis
Phenotype characterized by closely associated necrosis and melanization.
FlyBase:FBrf0155704
Phenotype that is a defect in immune response (GO:0006955). 'immune response' is defined as: 'Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.'
phenotypic_class
FBcv:0000448
immune response defective
Phenotype that is a defect in immune response (GO:0006955). 'immune response' is defined as: 'Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.'
FBC:DOS
GOC:add
GO_REF:0000022
Phenotype that is a defect in establishment of planar polarity (GO:0001736). 'establishment of planar polarity' is defined as: 'Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.'
tissue polarity defective
phenotypic_class
FBcv:0000449
For apical-basal polarity phenotypes of epithelia, the appropriate term is 'cell polarity defective'.
planar polarity defective
Phenotype that is a defect in establishment of planar polarity (GO:0001736). 'establishment of planar polarity' is defined as: 'Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.'
GOC:dph
Phenotype that is a change in the rate of some developmental process (GO:0032502) taking place prior to mature adulthood (defined as adult stage A3), compared to wild-type. Note, developmental processes include stages in development of the whole animal (e.g.- larval development) as well as specific sub-processes, such as dorsal closure.
phenotypic_class
FBcv:0000450
A more complete formalization would require a clause specifying stage. It might be possible to do this in OWL using the same system as we are using for lethal phase.
developmental rate defective
Phenotype that is a change in the rate of some developmental process (GO:0032502) taking place prior to mature adulthood (defined as adult stage A3), compared to wild-type. Note, developmental processes include stages in development of the whole animal (e.g.- larval development) as well as specific sub-processes, such as dorsal closure.
FBC:DOS
Phenotype that is a defect in wound healing (GO:0042060). 'wound healing' is defined as: 'The series of events that restore integrity to a damaged tissue, following an injury.'
phenotypic_class
FBcv:0000451
wound healing defective
Phenotype that is a defect in wound healing (GO:0042060). 'wound healing' is defined as: 'The series of events that restore integrity to a damaged tissue, following an injury.'
GOC:bf
PMID:15269788
Describes the origin of the mutation that causes a phenotype.
origin_of_mutation
FBcv:0000452
origin of mutation
Describes the origin of the mutation that causes a phenotype.
FBC:MMC
FlyBase miscellaneous CV
FBcv:0000453
piggyBac ammunition for transposable element mutagenesis
true
FBcv:0000455
origin_of_mutation
FBcv:0000454
synthetic
true
DNA change introduced by using an in vitro construct. The sequence of the in vitro construct determines the type of change.
change induced by in vitro construct
origin_of_mutation
FBcv:0000455
in vitro construct
DNA change introduced by using an in vitro construct. The sequence of the in vitro construct determines the type of change.
FBC:MMC
Sequence change introduced by using an in vitro construct that contains a fusion of the regulatory region of one gene on to the coding region of another. Examples in FlyBase include heat shock constructs, FRT flip out constructs and reporter genes.
change induced by an in vitro construct - regulatory fusion
origin_of_mutation
in vitro construct | regulatory fusion
FBcv:0000456
Notes on usage: Use this, rather than 'in vitro construct - deletion', for families of promoter deletions. Thus, a family of deletions of eve promoters driving Ecol\\lacZ will have regulatory fusion, but not deletion, as their mutagen.
in vitro construct - regulatory fusion
Sequence change introduced by using an in vitro construct that contains a fusion of the regulatory region of one gene on to the coding region of another. Examples in FlyBase include heat shock constructs, FRT flip out constructs and reporter genes.
FBC:DOS
Sequence change introduced by using an in vitro construct that contains a in-frame fusion of the open reading frames from two or more genes. In FlyBase, the resulting genes may be classified as fusion genes or tagged genes.
change induced by an in vitro construct - coding region fusion
origin_of_mutation
in vitro construct | coding region fusion
FBcv:0000457
in vitro construct - coding region fusion
Sequence change introduced by using an in vitro construct that contains a in-frame fusion of the open reading frames from two or more genes. In FlyBase, the resulting genes may be classified as fusion genes or tagged genes.
FBC:DOS
Mutation induced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene.
mutation induced by an in vitro construct - site directed mutagenesis
origin_of_mutation
in vitro construct | site directed mutagenesis
FBcv:0000458
in vitro construct - site directed mutagenesis
Mutation induced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene.
FBC:DOS
Sequence change introduced by an in vitro construct generated by internal deletion of some genomic sequence or cDNA.
change induced by an in vitro construct - deletion
origin_of_mutation
in vitro construct | deletion
FBcv:0000459
in vitro construct - deletion
Sequence change introduced by an in vitro construct generated by internal deletion of some genomic sequence or cDNA.
FBC:DOS
Sequence change introduced by an in vitro construct containing a genomic fragment that partially or fully rescues loss of function mutations or deletions of the gene whose sequence it carries.
change induced by an in vitro construct - genomic fragment
origin_of_mutation
in vitro construct | genomic fragment
FBcv:0000460
Notes on usage: 1. This term is applicable whether or not rescue using the construct is complete. 2. When a smaller rescue fragment is derived from a larger, by deletion of one or both ends, the mutagen shall be 'in vitro construct | deletion', with the larger being stated as the progenitor allele.
in vitro construct - genomic fragment
Sequence change introduced by an in vitro construct containing a genomic fragment that partially or fully rescues loss of function mutations or deletions of the gene whose sequence it carries.
FBC:DOS
Sequence change introduced by an in vitro construct that contains the wild-type open reading frame of a gene (without introns), the expression of which is controlled by a wild-type promoter of the same gene. Such constructs are often generated by fusing a cDNA to a genomic region containing promoter sequences, or more rarely by deletion of introns and other non-essential sequences from a genomic region, leaving a wild type coding region and promoter intact.
change induced by an in vitro construct - minigene
origin_of_mutation
in vitro construct | minigene
FBcv:0000461
in vitro construct - minigene
Sequence change introduced by an in vitro construct that contains the wild-type open reading frame of a gene (without introns), the expression of which is controlled by a wild-type promoter of the same gene. Such constructs are often generated by fusing a cDNA to a genomic region containing promoter sequences, or more rarely by deletion of introns and other non-essential sequences from a genomic region, leaving a wild type coding region and promoter intact.
FBC:DOS
Sequence change introduced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene resulting in a change to the change to the amino acids sequence encodes..
change induced by an in vitro construct - amino acid replacement
origin_of_mutation
in vitro construct | amino acid replacement
FBcv:0000462
in vitro construct - amino acid replacement
Sequence change introduced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene resulting in a change to the change to the amino acids sequence encodes..
FBC:DOS
Sequence change introduced by an in vitro construct designed to generate dsRNA for RNA interference (RNAi) experiments.
change induced by an in vitro construct - RNAi
origin_of_mutation
in vitro construct | RNAi
FBcv:0000463
in vitro construct - RNAi
Sequence change introduced by an in vitro construct designed to generate dsRNA for RNA interference (RNAi) experiments.
FBC:DOS
FBcv:0000455
in vitro construct | other
origin_of_mutation
FBcv:0000464
in vitro construct - other
true
Mutation found in a natural population.
origin_of_mutation
FBcv:0000465
natural population
Mutation found in a natural population.
FBC:MMC
Mutation caused by exposure to a temperature that is higher or lower than 25 degrees Celsius.
mutation induced by temperature treatment
origin_of_mutation
environmental treatment
FBcv:0000466
temperature
Mutation caused by exposure to a temperature that is higher or lower than 25 degrees Celsius.
FBC:MMC
Mutation induced by exposure to temperature that is lower than 25 degrees Celsius.
mutation induced by cold treatment
origin_of_mutation
cold-treatment
FBcv:0000467
cold
Mutation induced by exposure to temperature that is lower than 25 degrees Celsius.
FBC:MMC
Mutation induced by exposure to a temperature that is higher than 25 degrees Celsius.
mutation induced by heat treatment
origin_of_mutation
heat-treatment
FBcv:0000468
heat
Mutation induced by exposure to a temperature that is higher than 25 degrees Celsius.
FBC:MMC
Mutation caused by a spontaneous event.
mutation induced by spontaneous event
origin_of_mutation
FBcv:0000469
spontaneous
Mutation caused by a spontaneous event.
FBC:MMC
Sequence change induced by the genetic exchange that takes place between DNA sequences.
change induced by recombination
origin_of_mutation
FBcv:0000470
recombination
Sequence change induced by the genetic exchange that takes place between DNA sequences.
FBC:MC
ISBN:978-0-8153-3218-3
Sequence change caused by a DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor (GO:0035822).
change induced by gene conversion
origin_of_mutation
FBcv:0000471
Strictly, gene conversion (GO:0035822) defines only the endogenous process, not its use for engineered gene targeting.
gene conversion
Sequence change caused by a DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor (GO:0035822).
PMID:17846636
Mutation caused by a recombination event that causes the unequal exchange of small intralocus regions, usually leading to the formation of duplication and deficiency products.
mutation induced by intralocus exchange
origin_of_mutation
FBcv:0000472
intralocus exchange
Mutation caused by a recombination event that causes the unequal exchange of small intralocus regions, usually leading to the formation of duplication and deficiency products.
FBC:MC
FlyBase:FBrf0014117
FlyBase:FBrf0202435
Sequence change caused by a recombination event that causes an unequal exchange of genetic material between homologous or non-homologous regions.
change induced by unequal recombination
origin_of_mutation
FBcv:0000473
unequal recombination
Sequence change caused by a recombination event that causes an unequal exchange of genetic material between homologous or non-homologous regions.
FlyBase:FBrf0202435
Sequence change caused by the exchange of genetic material during mitosis that occurs at crossing over, and more frequently between homologous chromosomes.
change induced by mitotic recombination
origin_of_mutation
FBcv:0000474
mitotic recombination
Sequence change caused by the exchange of genetic material during mitosis that occurs at crossing over, and more frequently between homologous chromosomes.
FlyBase:FBrf0202435
Sequence change caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and an increase in the number of functional copies. It causes a reversion from mutant to wild-type phenotype.
mutation induced by magnification
origin_of_mutation
FBcv:0000475
magnification
Sequence change caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and an increase in the number of functional copies. It causes a reversion from mutant to wild-type phenotype.
FlyBase:FBrf0202435
FlyBase:FBrf0218934
Mutation that is caused by a recombination event that causes the breakdown of compound chromosome arms resulting in duplications or deletions in proximal regions.
mutation induced by detachment
origin_of_mutation
FBcv:0000476
detachment
Mutation that is caused by a recombination event that causes the breakdown of compound chromosome arms resulting in duplications or deletions in proximal regions.
FBC:MC
FlyBase:FBrf0202435
Mutation caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and a reduction in the number of functional copies. It leads to an aggravation of phenotype, in the case of a mutation causing a change from a wildtype to mutant phenotype or a change from a mutant to a more severe mutant phenotype.
mutation induced by reduction
origin_of_mutation
FBcv:0000477
reduction
Mutation caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and a reduction in the number of functional copies. It leads to an aggravation of phenotype, in the case of a mutation causing a change from a wildtype to mutant phenotype or a change from a mutant to a more severe mutant phenotype.
FlyBase:FBrf0026874
Sequence change induced by a recombination event catalyzed by a recombinase that occurs at specific nucleotide sequences.
change induced by site specific recombination
origin_of_mutation
FBcv:0000478
site specific recombination
Sequence change induced by a recombination event catalyzed by a recombinase that occurs at specific nucleotide sequences.
FlyBase:FBrf0202435
ISBN:978-0-8153-3218-3
Sequence change caused by a site specific recombination event catalyzed by the tyrosine recombinase FLPase, that recognizes minimal FLP recombination target (FRT) sites of 34 base pairs. For site specific integration, the recombination site consists of 48 base pairs containing an additional isolated base pair and a third 13 base pair direct repeat.
change induced by FLPase recombination
origin_of_mutation
FBcv:0000479
FLPase
Sequence change caused by a site specific recombination event catalyzed by the tyrosine recombinase FLPase, that recognizes minimal FLP recombination target (FRT) sites of 34 base pairs. For site specific integration, the recombination site consists of 48 base pairs containing an additional isolated base pair and a third 13 base pair direct repeat.
FlyBase:FBrf0201927
UniProt:P03870
Sequence change caused by the cleavage of an 18 base pair DNA sequence by the I-SceI endonuclease.
change induced by I-SceI endonuclease cleavage
origin_of_mutation
SCEI endonuclease
FBcv:0000480
I-SceI
Sequence change caused by the cleavage of an 18 base pair DNA sequence by the I-SceI endonuclease.
FlyBase:FBrf0128625
UniProt:P03882
Sequence change induced by a site specific recombination event catalyzed by the tyrosine recombinase cre. Recombination is induced between two 34 base pairs loxP sites. These consist of two 13 base pair perfect inverted repeats flanking an 8 base pair asymmetric spacer that confers directionality.
change induced by cre recombinase recombination
origin_of_mutation
Cre recombinase
FBcv:0000481
cre recombinase
Sequence change induced by a site specific recombination event catalyzed by the tyrosine recombinase cre. Recombination is induced between two 34 base pairs loxP sites. These consist of two 13 base pair perfect inverted repeats flanking an 8 base pair asymmetric spacer that confers directionality.
FlyBase:FBrf0201927
PMID:6954485
UniProt:P06956
Sequence change induced by chromosomal segregation.
change induced by segregation
origin_of_mutation
FBcv:0000482
segregation
Sequence change induced by chromosomal segregation.
FBC:MMC
Mutation induced by the mobilization of a transposable element.
mutation induced by transposable element activity
origin_of_mutation
FBcv:0000483
transposable element activity
Mutation induced by the mobilization of a transposable element.
FBC:MC
FlyBase:FBrf0202435
Mutation caused by hybrid dysgenesis that results from the mobilization of the I-element retrotransposon.
mutation induced by IR-hybrid dysgenesis
origin_of_mutation
IR
FBcv:0000484
IR-hybrid dysgenesis
Mutation caused by hybrid dysgenesis that results from the mobilization of the I-element retrotransposon.
FlyBase:FBrf0202435
Mutation induced by hybrid dysgenesis caused by the mobilization of the Stalker transposable element.
mutation induced by Stalker-hybrid dysgenesis
origin_of_mutation
FBcv:0000485
Stalker-hybrid dysgenesis
Mutation induced by hybrid dysgenesis caused by the mobilization of the Stalker transposable element.
FlyBase:FBrf0202435
Mutation induced by the transposable activity caused by a P-element, a DNA transposable element. The P-element is 2.9 kilobases in length with 31 base pairs inverted terminal repeats. Upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion. Mobilization is induced by the activity of a P-element transposase.
mutation induced by P-element activity
origin_of_mutation
FBcv:0000486
P-element activity
Mutation induced by the transposable activity caused by a P-element, a DNA transposable element. The P-element is 2.9 kilobases in length with 31 base pairs inverted terminal repeats. Upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion. Mobilization is induced by the activity of a P-element transposase.
FlyBase:FBrf0202435
Mutation caused by hybrid dysgenesis that results from the action of the P-element.
mutation induced by PM hybrid dysgenesis
origin_of_mutation
FBcv:0000487
PM hybrid dysgenesis
Mutation caused by hybrid dysgenesis that results from the action of the P-element.
FlyBase:FBrf0202435
Mutation induced by the mobilization of a P-element by the Delta2-3 transposase. The source of Delta2-3 is a stable genomic integration from which the third intron has been deleted.
mutation induced by P-element mobilization by Delta2-3 transposase
origin_of_mutation
&Dgr;2-3
FBcv:0000488
Delta2-3 transposase
Mutation induced by the mobilization of a P-element by the Delta2-3 transposase. The source of Delta2-3 is a stable genomic integration from which the third intron has been deleted.
FlyBase:FBrf0202435
Mutation caused by a P-element that is inserted into the genome and that is used to create more insertions at other sites.
mutation induced by jumpstarter mobilization
origin_of_mutation
Js
Jumpstarter
FBcv:0000489
jumpstarter activity
Mutation caused by a P-element that is inserted into the genome and that is used to create more insertions at other sites.
FlyBase:FBrf0202435
Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.1. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It is missing a 23 base pairs deletion of the 3' terminus compared to p pi25.1wc.
mutation induced by P-element mobilization by p pi25.1 supplied transposase
origin_of_mutation
p pi25.1
p&pgr;25.1
FBcv:0000490
p pi25.1 supplied transposase
Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.1. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It is missing a 23 base pairs deletion of the 3' terminus compared to p pi25.1wc.
FlyBase:FBrf0202435
Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.7wc. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It has an additional 23 base pairs deletion of the 3' terminus compared to p pi25.1.
mutation induced by P-element mobilization by p pi25.7wc supplied transposase
origin_of_mutation
p pi25.7wc
p&pgr;25.7wc
FBcv:0000491
p pi25.7wc
Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.7wc. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It has an additional 23 base pairs deletion of the 3' terminus compared to p pi25.1.
FlyBase:FBrf0202435
Mutation caused by PM hybrid dysgenesis that is induced by the higher frequency of recombination in certain male chromosomes.
mutation induced by male recombination
origin_of_mutation
MR
FBcv:0000492
male recombination induced by dysgenesis
Mutation caused by PM hybrid dysgenesis that is induced by the higher frequency of recombination in certain male chromosomes.
FlyBase:FBrf0202435
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Haifa, Israel.
mutation induced by MRh12 male recombination
origin_of_mutation
MRh12
FBcv:0000493
MRh12 induced male recombination
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Haifa, Israel.
FlyBase:FBrf0202435
Mutation caused by a male recombination event in the second and third chromosomes induced by a male recombination factor which is present in chromosomes extracted from a population in Harlingen, Texas.
mutation induced by MRT007 male recombination
origin_of_mutation
MRT007
FBcv:0000494
MRT007 induced male recombination
Mutation caused by a male recombination event in the second and third chromosomes induced by a male recombination factor which is present in chromosomes extracted from a population in Harlingen, Texas.
FlyBase:FBrf0202435
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece.
mutation induced by MRF23.5 male recombination
origin_of_mutation
MRF23.5
FBcv:0000495
MRF23.5 induced male recombination
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece.
FlyBase:FBrf0202435
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece.
mutation induced by MRF31.1 male recombination
origin_of_mutation
MRF31.1
FBcv:0000496
MRF31.1 induced male recombination
Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Patras, Greece.
FlyBase:FBrf0202435
Mutation induced by the transposable activity caused by hobo, a DNA transposable element. The hobo element is 3.0 kilobases in length with 12 base pairs inverted terminal repeats. After mobilization by the hobo transposase and upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion.
mutation induced by hobo element activity
origin_of_mutation
FBcv:0000497
hobo activity
Mutation induced by the transposable activity caused by hobo, a DNA transposable element. The hobo element is 3.0 kilobases in length with 12 base pairs inverted terminal repeats. After mobilization by the hobo transposase and upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion.
FlyBase:FBrf0202435
Mutation caused by hybrid dysgenesis that results from the mobilization of the hobo element.
mutation induced by hobo dysgenesis
origin_of_mutation
FBcv:0000498
hobo dysgenesis
Mutation caused by hybrid dysgenesis that results from the mobilization of the hobo element.
FlyBase:FBrf0202435
Mutation caused by the activity of the hobo element, mobilized by an hobo transposase which is produced from the supplied P-element helper plasmid HBL1.
mutation induced by Hobo transposase source HBL1
origin_of_mutation
Hobbled1
Hobo transposase source
FBcv:0000499
HBL1 supplied transposase
Mutation caused by the activity of the hobo element, mobilized by an hobo transposase which is produced from the supplied P-element helper plasmid HBL1.
FlyBase:FBrf0202435
Mutation induced by the transposable activity caused by mariner, a DNA transposable element. The mariner element is 1.3 kilobases in length with 28 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of these two bases upon insertion. Mobilization is induced by the activity of the mariner transposase.
mutation induced by mariner activity
origin_of_mutation
FBcv:0000500
mariner activity
Mutation induced by the transposable activity caused by mariner, a DNA transposable element. The mariner element is 1.3 kilobases in length with 28 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of these two bases upon insertion. Mobilization is induced by the activity of the mariner transposase.
FlyBase:FBrf0202435
Mutation induced by transposable activity caused by the gypsy retrovirus. The gypsy element is a 7.5 kilobases in length with 482 base pairs terminal repeats. Mobilization is induced by the activity of the gypsy element transposase.
mutation induced by gypsy element activity
origin_of_mutation
FBcv:0000501
gypsy element activity
Mutation induced by transposable activity caused by the gypsy retrovirus. The gypsy element is a 7.5 kilobases in length with 482 base pairs terminal repeats. Mobilization is induced by the activity of the gypsy element transposase.
FlyBase:FBrf0202435
Mutation induced by the transposable activity caused by piggyBac, a DNA transposable element. The piggyBac is 2.5 kilobases in length with 13 base pairs inverted terminal repeats. It specifically targets TTAA dinucleotides and generates a flanking duplication of these 4 base pairs upon insertion. Mobilization is induced by the activity of the piggyBac transposase.
mutation induced by piggyBac activity
origin_of_mutation
FBcv:0000502
piggyBac activity
Mutation induced by the transposable activity caused by piggyBac, a DNA transposable element. The piggyBac is 2.5 kilobases in length with 13 base pairs inverted terminal repeats. It specifically targets TTAA dinucleotides and generates a flanking duplication of these 4 base pairs upon insertion. Mobilization is induced by the activity of the piggyBac transposase.
FlyBase:FBrf0202435
Mutation induced by exposure to radiation.
mutation induced by irradiation
origin_of_mutation
FBcv:0000503
irradiation
Mutation induced by exposure to radiation.
FBC:MMC
Mutation induced by exposure to ionizing radiation.
mutation induced by ionizing irradiation
origin_of_mutation
FBcv:0000504
ionizing radiation
Mutation induced by exposure to ionizing radiation.
FBC:MMC
Mutation induced by exposure to alpha rays.
mutation induced by alpha ray irradiation
origin_of_mutation
&agr; ray
FBcv:0000505
alpha ray
Mutation induced by exposure to alpha rays.
FBC:MMC
Mutation induced by exposure to gamma rays.
mutation induced by gamma ray irradiation
origin_of_mutation
&ggr; ray
FBcv:0000506
gamma ray
Mutation induced by exposure to gamma rays.
FBC:MMC
Mutation induced by exposure to 60Co gamma rays.
mutation induced by 60Co gamma ray irradiation
origin_of_mutation
60Co &ggr; ray
FBcv:0000507
60Co gamma ray
Mutation induced by exposure to 60Co gamma rays.
FBC:MMC
Mutation induced by exposure to 137Cs gamma rays.
mutation induced by 137Cs gamma ray irradiation
origin_of_mutation
137Cs &ggr; ray
FBcv:0000508
137Cs gamma ray
Mutation induced by exposure to 137Cs gamma rays.
FBC:MMC
Mutation induced by exposure to 226Ra alpha rays.
mutation induced by 226Ra alpha ray irradiation
origin_of_mutation
226Ra &agr; ray
radium
FBcv:0000509
226Ra alpha ray
Mutation induced by exposure to 226Ra alpha rays.
FBC:MMC
Mutation induced by exposure to 32P radiation.
mutation induced by 32-P irradiation
origin_of_mutation
32-Phosphorous
FBcv:0000510
32P
Mutation induced by exposure to 32P radiation.
FBC:MMC
Mutation induced by exposure to 3H radiation.
mutation induced by 3H irradiation
origin_of_mutation
tritium
FBcv:0000511
3H
Mutation induced by exposure to 3H radiation.
FBC:MMC
Mutation induced by exposure to 3H-deoxycytidine radiation.
mutation induced by 3H-deoxycytidine irradiation
origin_of_mutation
FBcv:0000512
3H-deoxycytidine
Mutation induced by exposure to 3H-deoxycytidine radiation.
FBC:MMC
Mutation induced by exposure to 3H-thymidine radiation.
mutation induced by 3H-thymidine irradiation
origin_of_mutation
FBcv:0000513
3H-thymidine
Mutation induced by exposure to 3H-thymidine radiation.
FBC:MMC
Mutation induced by treatment in a Bevatron.
mutation induced by Bevatron irradiation
origin_of_mutation
FBcv:0000514
Bevatron
Mutation induced by treatment in a Bevatron.
FBC:MMC
Mutation induced by exposure to deuteron radiation.
mutation induced by deuteron irradiation
origin_of_mutation
FBcv:0000515
deuteron
Mutation induced by exposure to deuteron radiation.
FBC:MMC
Mutation induced by exposure to neutron radiation.
mutation induced by neutron irradiation
origin_of_mutation
FBcv:0000516
neutron
Mutation induced by exposure to neutron radiation.
FBC:MMC
Mutation induced by exposure to 252Cf fission neutron radiation.
mutation induced by 252Cf fission neutron irradiation
origin_of_mutation
FBcv:0000517
252Cf fission neutron
Mutation induced by exposure to 252Cf fission neutron radiation.
FBC:MMC
Mutation induced by exposure to X rays.
mutation induced by X ray irradiation
origin_of_mutation
FBcv:0000518
X ray
Mutation induced by exposure to X rays.
FBC:MMC
Mutation induced by exposure to non-ionizing radiation.
mutation induced by non-ionizing irradiation
origin_of_mutation
FBcv:0000519
non-ionizing radiation
Mutation induced by exposure to non-ionizing radiation.
FBC:MMC
Mutation induced by exposure to a magnetic field.
mutation induced by magnetic field irradiation
origin_of_mutation
FBcv:0000520
magnetic field
Mutation induced by exposure to a magnetic field.
FBC:MMC
Mutation induced by exposure to radio waves.
mutation induced by radio waves irradiation
origin_of_mutation
FBcv:0000521
radio waves
Mutation induced by exposure to radio waves.
FBC:MMC
Mutation induced by exposure to the stratosphere.
mutation induced by stratosphere irradiation
origin_of_mutation
FBcv:0000522
stratosphere
Mutation induced by exposure to the stratosphere.
FBC:MMC
Mutation induced by exposure to supersonic radiation.
mutation induced by supersonic irradiation
origin_of_mutation
FBcv:0000523
supersonic
Mutation induced by exposure to supersonic radiation.
FBC:MMC
Mutation induced by exposure to U.V. radiation.
mutation induced by U.V. irradiation
origin_of_mutation
FBcv:0000524
U.V.
Mutation induced by exposure to U.V. radiation.
FBC:MMC
A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
mutation induced by chemical exposure
origin_of_mutation
FBcv:0000525
chemical
A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
CHEBI:24431
Any chemical (FBcv:0000525) that has role some alkylating agent (CHEBI:22333).
mutation induced by alkylating agent exposure
origin_of_mutation
FBcv:0000526
alkylating agent
Any chemical (FBcv:0000525) that has role some alkylating agent (CHEBI:22333).
CHEBI:22333
No description.
mutation induced by diethyl sulfate exposure
origin_of_mutation
DES
FBcv:0000527
diethyl sulfate
No description.
CHEBI:34699
No description.
mutation induced by 2-chloroethyl methanesulfonate exposure
origin_of_mutation
CB1506
FBcv:0000528
2-chloroethyl methanesulfonate
No description.
CHEBI:19508
No description.
mutation induced by 2-fluoroethyl methanesulfonate exposure
origin_of_mutation
CB1522
FBcv:0000529
2-fluoroethyl methanesulfonate
No description.
CHEBI:19579
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
mutation induced by EMS exposure
mutation induced by ethyl methanesulfonate exposure
origin_of_mutation
CB1528
EMS
FBcv:0000530
ethyl methanesulfonate
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
CHEBI:23994
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
mutation induced by ENU exposure
mutation induced by ethyl nitrosourea exposure
origin_of_mutation
ENU
N-ethyl-N-nitrosourea
FBcv:0000531
ethyl nitrosourea
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
CHEBI:23995
N-ethyl-N-nitrosourea
CHEBI:23995
A methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
mutation induced by HMS exposure
mutation induced by hycanthon methanesulfonate exposure
origin_of_mutation
HMS
hycanthone mesylate
FBcv:0000532
hycanthon methanesulfonate
A methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
CHEBI:24624
hycanthone mesylate
CHEBI:24624
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol.
mutation induced by MMS exposure
mutation induced by methyl methanesulfonate exposure
origin_of_mutation
CB1540
MMS
FBcv:0000533
methyl methanesulfonate
A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol.
CHEBI:25255
An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
FBcv:0000536
mutation induced by bis(2-chloroethyl) sulfide exposure
mutation induced by mustard gas exposure
mutation induced by sulfur gas exposure
origin_of_mutation
1,1'-thiobis(2-chloroethane)
CB1735
mustard gas
sulfur mustard
FBcv:0000534
bis(2-chloroethyl) sulfide
An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
CHEBI:25434
1,1'-thiobis(2-chloroethane)
CHEBI:25434
mustard gas
CHEBI:25434
sulfur mustard
CHEBI:25434
An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position.
mutation induced by N-methyl-N'-nitro-N-nitrosoguanidine exposure
origin_of_mutation
MNNG
NNG
FBcv:0000535
N-methyl-N'-nitro-N-nitrosoguanidine
An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position.
CHEBI:21759
true
FlyBase miscellaneous CV
FBcv:0000537
minos ammunition for transposable element mutagenesis
true
No description.
mutation induced by carbamate exposure
origin_of_mutation
FBcv:0000538
carbamate
No description.
CHEBI:13941
A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.
mutation induced by urethane exposure
origin_of_mutation
FBcv:0000539
urethane
A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.
CHEBI:17967
No description.
mutation induced by vinyl carbamate exposure
origin_of_mutation
FBcv:0000540
vinyl carbamate
No description.
CHEBI:27292
Any chemical (FBcv:0000525) that has role some intercalator (CHEBI:24853).
mutation induced by intercalating agent exposure
origin_of_mutation
FBcv:0000541
intercalating agent
Any chemical (FBcv:0000525) that has role some intercalator (CHEBI:24853).
CHEBI:24853
No description.
mutation induced by mitomycin C exposure
origin_of_mutation
FBcv:0000542
mitomycin C
No description.
CHEBI:27504
No description.
mutation induced by quinacrine mustard exposure
origin_of_mutation
2-methoxy-6-[3-(ethyl-2-chloroethyl)aminopropylamino]acridine
ICR 100
FBcv:0000543
Mapped to CHEBI on basis of synonym - quinacrine mustard. Originally primary name, ICR 100 is now relegated to a synonym.
quinacrine mustard
No description.
CHEBI:37595
ICR 100
CHEBI:37595
No description.
mutation induced by ICR 170 exposure
origin_of_mutation
2-methoxy-6-dichloro-9-(3-ethyl-2-chloroethyl-aminopropylamino)acridine-dihydrochloride
FBcv:0000544
ICR 170
No description.
CHEBI:21183
A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae.
mutation induced by 1,2-dibromoethane exposure
origin_of_mutation
DBE
FBcv:0000545
1,2-dibromoethane
A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae.
CHEBI:28534
A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
mutation induced by 1,2-dichloroethane exposure
origin_of_mutation
DCE
FBcv:0000546
1,2-dichloroethane
A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
CHEBI:27789
A haloalkane that is bromoethane substituted by chlorine at position 2.
mutation induced by 1-bromo-2-chloroethane exposure
origin_of_mutation
BCE
FBcv:0000547
1-bromo-2-chloroethane
A haloalkane that is bromoethane substituted by chlorine at position 2.
CHEBI:19032
A molecule that can substitute for a normal nucleobase in nucleic acids.
origin_of_mutation
nucleobase analogue
FBcv:0000548
base analog
A molecule that can substitute for a normal nucleobase in nucleic acids.
CHEBI:67142
nucleobase analogue
CHEBI:67142
A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.
mutation induced by 5-bromouracil exposure
origin_of_mutation
FBcv:0000549
5-bromouracil
A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen.
CHEBI:20552
A uridine having a bromo substituent at the 5-position.
mutation induced by 5-bromouridine exposure
origin_of_mutation
FBcv:0000550
5-bromouridine
A uridine having a bromo substituent at the 5-position.
CHEBI:20553
Any chemical (FBcv:0000525) that has role some enzyme inhibitor (CHEBI:23924).
mutation induced by enzyme inhibitor exposure
origin_of_mutation
FBcv:0000551
enzyme inhibitor
Any chemical (FBcv:0000525) that has role some enzyme inhibitor (CHEBI:23924).
CHEBI:23924
No description.
mutation induced by aminopterin exposure
origin_of_mutation
FBcv:0000552
aminopterin
No description.
CHEBI:22526
A molecular entity that contains no carbon.
inorganic molecular entity
mutation induced by inorganic compound exposure
origin_of_mutation
FBcv:0000553
inorganic compound
A molecular entity that contains no carbon.
CHEBI:24835
inorganic molecular entity
CHEBI:24835
A metal sulfate compound having copper(2+) as the metal ion.
mutation induced by cupric sulfate
origin_of_mutation
copper(2+) sulfate
FBcv:0000554
cupric sulfate
A metal sulfate compound having copper(2+) as the metal ion.
CHEBI:23414
copper(2+) sulfate
CHEBI:23414
No description.
mutation induced by H3BO3 exposure
origin_of_mutation
FBcv:0000555
H3BO3
No description.
CHEBI:33118
No description.
mutation induced by sodium bisulphite exposure
origin_of_mutation
FBcv:0000556
sodium bisulphite
No description.
CHEBI:26709
A metal fluoride salt with a Na(+) counterion.
mutation induced by sodium fluoride exposure
origin_of_mutation
FBcv:0000557
sodium fluoride
A metal fluoride salt with a Na(+) counterion.
CHEBI:28741
Mutation induced by exposure to epoxy hydrocarbon.
mutation induced by epoxy hydrocarbon exposure
origin_of_mutation
FBcv:0000558
epoxy hydrocarbon
Mutation induced by exposure to epoxy hydrocarbon.
FBC:MMC
No description.
mutation induced by diepoxybutane exposure
origin_of_mutation
DEB
erythritol anhydride
FBcv:0000559
diepoxybutane
No description.
CHEBI:23704
No description.
mutation induced by diepoxyoctane exposure
origin_of_mutation
1,2:7,8-diepoxyoctane
FBcv:0000560
diepoxyoctane
No description.
CHEBI:23705
1,2:7,8-diepoxyoctane
CHEBI:23705
FBcv:0000525
origin_of_mutation
FBcv:0000561
unclassified chemical
true
No description.
mutation induced by 1,2:5,6-dibenzanthracene exposure
origin_of_mutation
FBcv:0000562
1,2:5,6-dibenzanthracene
No description.
CHEBI:35299
A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups.
mutation induced by 1,4-dimethanesulfonoxy-1,4-dimethylbutane exposure
origin_of_mutation
1,4-dimethanesulfonoxy-1:4-dimethylbutane
CB2348
dimethylmyleran
FBcv:0000563
1,4-dimethanesulfonoxy-1,4-dimethylbutane
A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups.
CHEBI:67107
dimethylmyleran
CHEBI:67107
Mutation induced by exposure to 1,4-dimethanesulfonoxybut-2-yne.
mutation induced by 1,4-dimethanesulfonoxybut-2-yne exposure
origin_of_mutation
CB2058
FBcv:0000564
1,4-dimethanesulfonoxybut-2-yne
Mutation induced by exposure to 1,4-dimethanesulfonoxybut-2-yne.
FBC:MMC
Dominance relationships describe the dependence of the expression of a phenotypic attribute of an allele on the genotype at the locus in question. An allele might be recessive with respect to one phenotypic attribute, but dominant with respect to another.
dominance_qualifier
FBcv:0000565
dominance relationship qualifier
Dominance relationships describe the dependence of the expression of a phenotypic attribute of an allele on the genotype at the locus in question. An allele might be recessive with respect to one phenotypic attribute, but dominant with respect to another.
FBC:rd
Mutation induced by exposure to 1,6-dimethylsulfonoxy D-mannitol.
mutation induced by 1,6-dimethylsulfonoxy D-mannitol exposure
origin_of_mutation
CB2511
FBcv:0000566
1,6-dimethylsulfonoxy D-mannitol
Mutation induced by exposure to 1,6-dimethylsulfonoxy D-mannitol.
FBC:MMC
Mutation induced by exposure to 1,6-dimethylsulfonoxy L-mannitol.
mutation induced by 1,6-dimethylsulfonoxy L-mannitol exposure
origin_of_mutation
CB2628
FBcv:0000567
1,6-dimethylsulfonoxy L-mannitol
Mutation induced by exposure to 1,6-dimethylsulfonoxy L-mannitol.
FBC:MMC
No description.
mutation induced by 1-amino-2-naphthol-4-sulfonic acid exposure
origin_of_mutation
FBcv:0000568
1-amino-2-naphthol-4-sulfonic acid
No description.
CHEBI:19024
A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
mutation induced by lucanthone exposure
origin_of_mutation
1-diethylaminoethylethylamino-4-methyl-thioxanthenone
1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
lucanthone
FBcv:0000569
lucanthone
A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.
CHEBI:51052
1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one
CHEBI:51052
lucanthone
CHEBI:51052
A hydroxyether that is ethanol substituted by a methoxy group at position 2.
mutation induced by 2-methoxyethanol exposure
origin_of_mutation
FBcv:0000570
2-methoxyethanol
A hydroxyether that is ethanol substituted by a methoxy group at position 2.
CHEBI:46790
A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups.
mutation induced by 2,5-bis(ethyleneimino)-1,4-benzoquinone exposure
origin_of_mutation
2,5,-bisethylene-imine-1,4-benzoquinone
FBcv:0000571
2,5-bis(ethyleneimino)-1,4-benzoquinone
A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups.
CHEBI:19363
A member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively.
mutation induced by 7-bromomethyl-12-methylbenz[a]anthracene exposure
origin_of_mutation
7-bromomethyl 12 methyl benz&agr; anthracine
7-bromomethyl 12 methyl benzalpha anthracine
7-bromomethyl-12-methyltetraphene
FBcv:0000572
7-bromomethyl-12-methylbenz[a]anthracene
A member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively.
CHEBI:20787
7-bromomethyl-12-methyltetraphene
CHEBI:20787
No description.
mutation induced by actinomycin D exposure
origin_of_mutation
FBcv:0000573
actinomycin D
No description.
CHEBI:27666
An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
mutation induced by benzo(alpha)pyrene exposure
origin_of_mutation
benzo(&agr;)pyrene
benzo[a]pyrene
FBcv:0000574
benzo(alpha)pyrene
An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
CHEBI:29865
benzo[a]pyrene
CHEBI:29865
A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
mutation induced by caffeine exposure
origin_of_mutation
FBcv:0000575
caffeine
A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
CHEBI:27732
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
mutation induced by cisplatin exposure
origin_of_mutation
cis-dichlorodiammineplatinum(II)
FBcv:0000576
cisplatin
A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
CHEBI:27899
An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.
mutation induced by colchicine exposure
origin_of_mutation
FBcv:0000577
colchicine
An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.
CHEBI:23359
A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
mutation induced by dimethyl sulfoxide exposure
origin_of_mutation
FBcv:0000578
dimethyl sulfoxide
A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
CHEBI:28262
High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
mutation induced by DNA treatment
origin_of_mutation
FBcv:0000579
DNA
High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
CHEBI:16991
An ether in which the oxygen atom is linked to two ethyl groups.
mutation induced by ethyl ether exposure
origin_of_mutation
FBcv:0000580
ethyl ether
An ether in which the oxygen atom is linked to two ethyl groups.
CHEBI:35702
No description.
mutation induced by ethylenimine exposure
origin_of_mutation
EI
FBcv:0000581
ethylenimine
No description.
CHEBI:30969
A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.
mutation induced by ethylene oxide exposure
origin_of_mutation
ethylene oxide
oxirane
FBcv:0000582
ethylene oxide
A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom.
CHEBI:27561
ethylene oxide
CHEBI:27561
oxirane
CHEBI:27561
No description.
mutation induced by fagaronine exposure
origin_of_mutation
FBcv:0000583
fagaronine
No description.
CHEBI:28954
An aldehyde resulting from the formal oxidation of methanol.
mutation induced by formaldehyde exposure
origin_of_mutation
FBcv:0000584
formaldehyde
An aldehyde resulting from the formal oxidation of methanol.
CHEBI:16842
A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
mutation induced by hesperidine exposure
origin_of_mutation
hesperidin
FBcv:0000585
hesperidine
A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
CHEBI:28775
hesperidin
CHEBI:28775
No description.
mutation induced by HMM exposure
mutation induced by hexamethylmelamine exposure
origin_of_mutation
HMM
altretamine
FBcv:0000586
hexamethylmelamine
No description.
CHEBI:24564
No description.
mutation induced by HMPA exposure
mutation induced by hexamethylphosphoramide exposure
origin_of_mutation
HMPA
FBcv:0000587
hexamethylphosphoramide
No description.
CHEBI:24565
Chemical element with atomic number 53.
mutation induced by iodine exposure
origin_of_mutation
FBcv:0000588
iodine
Chemical element with atomic number 53.
CHEBI:24859
No description.
mutation induced by Janus green B exposure
origin_of_mutation
Janus green B chloride
FBcv:0000589
Janus green B
No description.
CHEBI:21184
Janus green B chloride
CHEBI:21184
No description.
mutation induced by methoxy diethylnitrosamine exposure
origin_of_mutation
1-methoxy-N-nitrosodiethylamine
FBcv:0000590
Mapped to CHEBI:25234 (1-methoxy-N-nitrosodiethylamine) based on synonym of nitrosodiethylamine being diethylnitrosamine and CHEBI:25234 being classified as a mutagen.
methoxy diethylnitrosamine
No description.
CHEBI:25234
1-methoxy-N-nitrosodiethylamine
CHEBI:25234
Mutation induced by exposure to natural gas.
mutation induced by natural gas exposure
origin_of_mutation
FBcv:0000591
natural gas
Mutation induced by exposure to natural gas.
FBC:MMC
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
mutation induced by MNU exposure
mutation induced by nitrosomethyl urea exposure
origin_of_mutation
MNU
N-methyl-N-nitrosourea
FBcv:0000592
nitrosomethyl urea
A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
CHEBI:50102
N-methyl-N-nitrosourea
CHEBI:50102
No description.
mutation induced by DMN exposure
mutation induced by N-nitrosodimethylamine exposure
origin_of_mutation
DMN
FBcv:0000593
N-nitrosodimethylamine
No description.
CHEBI:35807
No description.
mutation induced by p-N,N-di(2-chloroethyl)aminophenylvaleric acid exposure
origin_of_mutation
CB1356
FBcv:0000594
p-N,N-di(2-chloroethyl)aminophenylvaleric acid
No description.
CHEBI:25813
No description.
mutation induced by p-N,N-di-(2-chloroethyl)amino-D-phenylalanine exposure
origin_of_mutation
CB3026
FBcv:0000595
p-N,N-di-(2-chloroethyl)amino-D-phenylalanine
No description.
CHEBI:25814
A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
mutation induced by melphalan exposure
mutation induced by p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine exposure
origin_of_mutation
CB3007
melphalan
FBcv:0000596
p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine
A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
CHEBI:28876
melphalan
CHEBI:28876
No description.
mutation induced by p-N,N-di-(2-chloroethyl)amino-L-phenylalanine exposure
origin_of_mutation
CB3025
FBcv:0000597
p-N,N-di-(2-chloroethyl)amino-L-phenylalanine
No description.
CHEBI:25816
FlyBase miscellaneous CV
FBcv:0000598
Consider - FBsv:0001009.
dominant temperature-sensitive lethal balancer
true
No description.
mutation induced by p-N,N-di-(2-chloroethyl)aminophenylethylamine exposure
origin_of_mutation
CB3034
FBcv:0000599
p-N,N-di-(2-chloroethyl)aminophenylethylamine
No description.
CHEBI:25818
No description.
mutation induced by p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine exposure
origin_of_mutation
CB305
FBcv:0000600
p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine
No description.
CHEBI:25829
No description.
mutation induced by quinhydrone exposure
origin_of_mutation
FBcv:0000601
quinhydrone
No description.
CHEBI:26491
No description.
mutation induced by S-2-chloroethylcysteine exposure
origin_of_mutation
CB1592
FBcv:0000602
S-2-chloroethylcysteine
No description.
CHEBI:22025
No description.
mutation induced by styryl quinoline exposure
origin_of_mutation
CB3086
FBcv:0000603
styryl quinoline
No description.
CHEBI:26800
A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups.
mutation induced by triaziquone exposure
origin_of_mutation
FBcv:0000604
triaziquone
A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups.
CHEBI:27090
No description.
mutation induced by triethylenemelamine exposure
origin_of_mutation
CB1246
TEM
tretamine
FBcv:0000605
triethylenemelamine
No description.
CHEBI:27919
tretamine
CHEBI:27919
Assay method used to generate an allele.
FBcv:0000807
mode_of_assay
FBcv:0000606
This term has been obsoleted because it is no longer used and relevant. mc151005
allele assay method
true
Assay method used to generate an allele.
FBC:MMC
FBcv:0000807
mode_of_assay
FBcv:0000607
This term has been obsoleted because it is no longer used and relevant. mc151005
In transgenic Drosophila
true
FBcv:0000807
mode_of_assay
FBcv:0000608
This term has been obsoleted because it is no longer used and relevant. mc151005
Whole-organism transient assay
true
FBcv:0000807
abbrev:3
mode_of_assay
FBcv:0000609
This term has been obsoleted because it is no longer used and relevant. mc151005
Drosophila cell culture
true
FBcv:0000807
abbrev:5
mode_of_assay
FBcv:0000610
This term has been obsoleted because it is no longer used and relevant. mc151005
In transgenic Drosophila (allele of one drosophilid species in genome of another drosophilid)
true
FBcv:0000807
abbrev:6
mode_of_assay
FBcv:0000611
This term has been obsoleted because it is no longer used and relevant. mc151005
Whole-organism transient assay (allele from one drosophilid species assayed in another drosophilid)
true
FBcv:0000807
abbrev:7
mode_of_assay
FBcv:0000612
This term has been obsoleted because it is no longer used and relevant. mc151005
In transgenic Drosophila (allele of foreign species in genome of drosophilid)
true
FBcv:0000807
abbrev:8
mode_of_assay
FBcv:0000613
This term has been obsoleted because it is no longer used and relevant. mc151005
Whole-organism transient assay (allele of foreign species assayed in drosophilid)
true
FlyBase miscellaneous CV
FBcv:0000614
Consider - FBsv:0000000.
stock descriptor
true
FlyBase miscellaneous CV
FBcv:0000615
extracted wild-type chromosome
true
FlyBase miscellaneous CV
FBcv:0000616
I don't think this is a useful term.
laboratory stock
true
FlyBase miscellaneous CV
FBcv:0000617
selected wild-type stock
true
FlyBase miscellaneous CV
FBcv:0000618
Consider - FBsv:0001005.
wild-type stock
true
FlyBase miscellaneous CV
FBcv:0000619
Consider - FBsv:0001002.
isogenic stock
true
Qualifier that describes the relation between two phenotypes that are due to genotypes g1 and g2.
genetic_interaction_type
FBcv:0000620
genetic interaction qualifier
Qualifier that describes the relation between two phenotypes that are due to genotypes g1 and g2.
FBC:MMC
The genotype g1 is a suppressor of genotype g2 if (and only if) the phenotype due to g2 is made less severe by g1.
genetic_interaction_type
FBcv:0000621
Not used directly in curation, but automatically inferred from its inverse (suppressible).
suppressor
The genotype g1 is a suppressor of genotype g2 if (and only if) the phenotype due to g2 is made less severe by g1.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
A phenotype due to genotype g1 is suppressible by genotype g2 if the if the phenotype due to the genotype g1g2 is less severe than that due to g1 alone.
genetic_interaction_type
FBcv:0000622
suppressible
A phenotype due to genotype g1 is suppressible by genotype g2 if the if the phenotype due to the genotype g1g2 is less severe than that due to g1 alone.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
Genotype g1 is enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
genetic_interaction_type
FBcv:0000623
Not used directly in curation, but automatically inferred from its inverse (enhanceable).
enhancer
Genotype g1 is enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
A phenotype due to genotype g1 is enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
genetic_interaction_type
FBcv:0000624
enhanceable
A phenotype due to genotype g1 is enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
Genotype g1 is a non-enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is not more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
genetic_interaction_type
FBcv:0000625
Not used directly in curation, but automatically inferred from its inverse (non-enhanceable).
non-enhancer
Genotype g1 is a non-enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is not more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
FBC:MMC
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
A phenotype due to genotype g1 is non-enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
genetic_interaction_type
FBcv:0000626
non-enhanceable
A phenotype due to genotype g1 is non-enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
The genotype g1 is a non-suppressor of genotype g2 if (and only if) the phenotype due to g2 is not made less severe by g1.
genetic_interaction_type
FBcv:0000627
Not used directly in curation, but automatically inferred from its inverse (non-suppressible).
non-suppressor
The genotype g1 is a non-suppressor of genotype g2 if (and only if) the phenotype due to g2 is not made less severe by g1.
FBC:MMC
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
A phenotype due to genotype g1 is non-suppressible by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no less severe than the phenotype due to g1 alone.
genetic_interaction_type
FBcv:0000628
non-suppressible
A phenotype due to genotype g1 is non-suppressible by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no less severe than the phenotype due to g1 alone.
FBC:DOS
FlyBase:FBrf0000957
ISBN:978-0-387-52054-4
FlyBase miscellaneous CV
FBcv:0000629
dominant temperature-sensitive lethal balancer for chromosome 2
true
FlyBase miscellaneous CV
FBcv:0000630
dominant temperature-sensitive lethal balancer for chromosome 3
true
FlyBase miscellaneous CV
FBcv:0000631
DrosDel Project deficiency core kit stock
true
FlyBase miscellaneous CV
FBcv:0000632
Consider - FBsv:0000601.
Bloomington Stock Center deficiency kit stock
true
FlyBase miscellaneous CV
FBcv:0000633
Exelixis deficiency kit stock
true
FlyBase miscellaneous CV
FBcv:0000634
duplication kit stock
true
FlyBase miscellaneous CV
FBcv:0000635
Consider - FBsv:0000603.
Cambridge 2 duplication kit stock
true
FlyBase miscellaneous CV
FBcv:0000636
Consider - FBsv:0000602.
Bloomington duplication kit stock
true
FlyBase miscellaneous CV
FBcv:0000637
Gene Disruption Project stock
true
FlyBase miscellaneous CV
FBcv:0000638
Consider - FBsv:0001003.
sequenced strain
true
FlyBase miscellaneous CV
FBcv:0000639
Consider - FBsv:0000604.
Golic gene replacement kit stock
true
FlyBase miscellaneous CV
FBcv:0000640
Golic laboratory gene replacement kit stock
true
FlyBase miscellaneous CV
FBcv:0000641
stock by cytotype
true
FlyBase miscellaneous CV
FBcv:0000642
H cytotype stock
true
FlyBase miscellaneous CV
FBcv:0000643
hobo family transposable element insertions present
true
FlyBase miscellaneous CV
FBcv:0000644
hobo family transposable element insertions absent
true
FlyBase miscellaneous CV
FBcv:0000645
P cytotype stock
true
FlyBase miscellaneous CV
FBcv:0000646
P-element family transposable element insertions absent
true
FlyBase miscellaneous CV
FBcv:0000647
P-element family transposable element insertions present
true
FlyBase miscellaneous CV
FBcv:0000648
mapping stock
true
FlyBase miscellaneous CV
FBcv:0000649
visible allele recombination mapping stock
true
Work consisting of a statement of the opinions, beliefs, and policy of the editor or publisher of a journal, usually on current matters of medical or scientific significance to the medical community or society at large.
MeSH:D016421
pub_type
FBcv:0000650
editorial
Work consisting of a statement of the opinions, beliefs, and policy of the editor or publisher of a journal, usually on current matters of medical or scientific significance to the medical community or society at large.
MeSH:D016421
FBcv:0000199
pub_type
FBcv:0000651
This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199
meeting report
true
A publication containing a collection of separate articles written by distinct authors.
Parent publication
multipub
multipublication
pub_type
FBcv:0000652
compendium
A publication containing a collection of separate articles written by distinct authors.
FBC:SM
Parent publication
FBC:SM
multipub
FBC:SM
multipublication
FBC:SM
Restricted to unknown subtype(s) of a specified type.
expression_qualifier
FBcv:0000653
subset
Restricted to unknown subtype(s) of a specified type.
FBC:DS
Qualifier that describes the expression pattern of an embryo.
embryonic_pattern_qualifier
FBcv:0000654
embryonic pattern qualifier
Qualifier that describes the expression pattern of an embryo.
FBC:MMC
VDRC
Vienna
FlyBase miscellaneous CV
FBcv:0000655
Consider - FBsv:0000107.
Vienna Drosophila RNAi Center
true
FlyBase miscellaneous CV
FBcv:0000656
Consider - FBsv:0000008.
frozen specimen
true
FlyBase miscellaneous CV
FBcv:0000657
mutant stock
true
FlyBase miscellaneous CV
FBcv:0000658
DrosDel Project deficiency stock
true
FlyBase miscellaneous CV
FBcv:0000659
deficiency stock
true
FlyBase miscellaneous CV
FBcv:0000660
Consider - FBsv:0000501.
inbred line
true
FlyBase miscellaneous CV
FBcv:0000661
Consider - FBsv:0000502.
isofemale line
true
A stock established from flies collected in the wild within the past 3 years.
FlyBase miscellaneous CV
FBcv:0000662
Consider - FBsv:0000504.
recently collected stock
true
A stock established from flies collected in the wild within the past 3 years.
FBC:KM
FlyBase miscellaneous CV
FBcv:0000663
transposable element-containing stock
true
FlyBase miscellaneous CV
FBcv:0000664
duplication stock
true
Phenotype that is an abnormality in body size compared to wild-type animals raised under the same conditions as the animals exhibiting the phenotype.
phenotypic_class
FBcv:0000665
body size defective
Phenotype that is an abnormality in body size compared to wild-type animals raised under the same conditions as the animals exhibiting the phenotype.
FBC:DOS
FBcv:0000199
pub_type
FBcv:0000666
This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199
conference proceedings
true
A set of related web pages containing content such as text, images, video, audio, etc., prepared and maintained as a collection of information on a particular subject.
pub_type
FBcv:0000667
website
A set of related web pages containing content such as text, images, video, audio, etc., prepared and maintained as a collection of information on a particular subject.
FBC:SM
Phenotype that is a defect in cell adhesion (GO:0007155). 'cell adhesion' is defined as: 'The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.'
phenotypic_class
FBcv:0000668
cell adhesion defective
Phenotype that is a defect in cell adhesion (GO:0007155). 'cell adhesion' is defined as: 'The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.'
FBC:DOS
GOC:hb
GOC:pf
Phenotype that is a defect in hatching behavior (GO:0035187). 'hatching behavior' is defined as: 'The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.'
hatching behaviour defective
phenotypic_class
FBcv:0000669
hatching behavior defective
Phenotype that is a defect in hatching behavior (GO:0035187). 'hatching behavior' is defined as: 'The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.'
FBC:DOS
GOC:pr
PMID:10436051
Phenotype that is a defect in eclosion (GO:0007562). 'eclosion' is defined as: 'The emergence of an adult insect from a pupa case.'
phenotypic_class
FBcv:0000670
eclosion defective
Phenotype that is a defect in eclosion (GO:0007562). 'eclosion' is defined as: 'The emergence of an adult insect from a pupa case.'
FBC:DOS
GOC:dgh
GOC:dos
GOC:mah
ISBN:0198600461
Phenotype that is a defect in cell cycle (GO:0007049). 'cell cycle' is defined as: 'The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.'
phenotypic_class
FBcv:0000671
cell cycle defective
Phenotype that is a defect in cell cycle (GO:0007049). 'cell cycle' is defined as: 'The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.'
FBC:DOS
GOC:go_curators
GOC:mtg_cell_cycle
Phenotype that is a defect in endomitotic cell cycle (GO:0007113). 'endomitotic cell cycle' is defined as: 'A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.'
endocycle defective
phenotypic_class
FBcv:0000672
endomitotic cell cycle defective
Phenotype that is a defect in endomitotic cell cycle (GO:0007113). 'endomitotic cell cycle' is defined as: 'A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.'
FBC:DOS
GOC:curators
GOC:dos
GOC:expert_vm
FlyBase miscellaneous CV
FBcv:0000673
Consider - FBsv:0001003.
sequenced whole genome stock
true
FlyBase miscellaneous CV
FBcv:0000674
phiC31 based integration system
true
FlyBase miscellaneous CV
FBcv:0000675
phiC31 docking site stock
true
FlyBase miscellaneous CV
FBcv:0000676
Consider - FBsv:0000503.
multi-female collection
true
60-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
djs93
2009-05-28T03:54:39Z
spatial_qualifier
FBcv:0000677
60-70% egg length
60-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
80-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
djs93
2009-05-28T03:55:30Z
spatial_qualifier
FBcv:0000678
80-100% egg length
80-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo.
FBC:DOS
Phenotype that is a defect in circadian behavior (GO:0048512). 'circadian behavior' is defined as: 'The specific behavior of an organism that recurs with a regularity of approximately 24 hours.'
djs93
2009-11-30T11:06:35Z
phenotypic_class
FBcv:0000679
circadian behavior defective
Phenotype that is a defect in circadian behavior (GO:0048512). 'circadian behavior' is defined as: 'The specific behavior of an organism that recurs with a regularity of approximately 24 hours.'
FBC:DOS
GOC:bf
GOC:go_curators
GOC:pr
Phenotype that is a defect in proboscis extension reflex (GO:0007637). 'proboscis extension reflex' is defined as: 'The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.'
phenotypic_class
FBcv:0000680
proboscis extension reflex defective
Phenotype that is a defect in proboscis extension reflex (GO:0007637). 'proboscis extension reflex' is defined as: 'The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.'
FB:FBrf0044924
FBC:DOS
GOC:jid
Phenotype that is a defect in sensory perception (GO:0007600). 'sensory perception' is defined as: 'The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'
djs93
2010-02-23T12:28:26Z
phenotypic_class
FBcv:0000681
sensory perception defective
Phenotype that is a defect in sensory perception (GO:0007600). 'sensory perception' is defined as: 'The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'
FBC:DOS
GOC:ai
GOC:dph
Phenotype that is a defect in sensory perception of touch (GO:0050975). 'sensory perception of touch' is defined as: 'The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).'
phenotypic_class
touch perception defective
FBcv:0000682
touch perception defective
Phenotype that is a defect in sensory perception of touch (GO:0050975). 'sensory perception of touch' is defined as: 'The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).'
FBC:DOS
GOC:ai
Phenotype that is a defect in response to temperature stimulus (GO:0009266). 'response to temperature stimulus' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.'
djs93
2010-02-23T12:51:02Z
phenotypic_class
FBcv:0000683
temperature response defective
Phenotype that is a defect in response to temperature stimulus (GO:0009266). 'response to temperature stimulus' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.'
FBC:DOS
GOC:hb
Phenotype that is a defect in response to cold (GO:0009409). 'response to cold' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.'
djs93
2010-02-23T02:11:27Z
phenotypic_class
FBcv:0000684
cold stress response defective
Phenotype that is a defect in response to cold (GO:0009409). 'response to cold' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.'
FBC:DOS
GOC:lr
Parental effects describe the dependence of the expression of a phenotypic attribute of an allele on the parent from which that allele is inherited.
genotype_to_phenotype_relation
FBcv:0000685
parental effect
Parental effects describe the dependence of the expression of a phenotypic attribute of an allele on the parent from which that allele is inherited.
FBC:rd
Phenotype that is a defect in axis specification (GO:0009798). 'axis specification' is defined as: 'The establishment, maintenance and elaboration of a pattern along a line or around a point.'
phenotypic_class
FBcv:0000686
This phenotypic class does not encompass planar polarity.
axis specification defective
Phenotype that is a defect in axis specification (GO:0009798). 'axis specification' is defined as: 'The establishment, maintenance and elaboration of a pattern along a line or around a point.'
FBC:DOS
GOC:dph
GOC:go_curators
GOC:isa_complete
Descriptor that relates to aspects of a balancer.
FlyBase miscellaneous CV
FBcv:0000687
balancer descriptor
Descriptor that relates to aspects of a balancer.
FBC:MMC
An allele that completely lacks function, coding either for a completely inactive gene product or none at all.
djs93
2010-09-06T03:57:21Z
allele_class
amorph
null
FBcv:0000688
amorphic allele
An allele that completely lacks function, coding either for a completely inactive gene product or none at all.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to completely lack function, producing either a completely inactive gene product or none at all.
djs93
2010-09-06T03:57:49Z
molecular null
allele_class
FBcv:0000689
amorphic allele - molecular evidence
An allele shown by molecular evidence to completely lack function, producing either a completely inactive gene product or none at all.
FlyBase:FBrf0049147
Allele that makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2010-09-06T03:58:15Z
hypomorph
allele_class
FBcv:0000690
hypomorphic allele
Allele that makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2010-09-06T03:59:31Z
allele_class
FBcv:0000691
hypomorphic allele - molecular evidence
An allele shown by molecular evidence to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FlyBase:FBrf0049147
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern compared to wild-type.
djs93
2010-09-06T04:01:04Z
allele_class
FBcv:0000692
neomorphic allele - molecular evidence
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern compared to wild-type.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
Allele shown by molecular evidence to make either a functionally wild-type gene product at increased levels or a gene product with the same function as wild-type but with increased activity.
djs93
2010-09-06T04:01:04Z
allele_class
FBcv:0000693
hypermorphic allele - molecular evidence
Allele shown by molecular evidence to make either a functionally wild-type gene product at increased levels or a gene product with the same function as wild-type but with increased activity.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product.
djs93
2010-09-06T04:01:04Z
allele_class
dominant negative
FBcv:0000694
antimorphic allele - molecular evidence
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product.
FlyBase:FBrf0049147
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product.
djs93
2010-09-06T04:02:05Z
allele_class
antimorph
FBcv:0000695
antimorphic allele
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type.
djs93
2010-09-06T04:02:45Z
allele_class
hypermorph
FBcv:0000696
hypermorphic allele
An allele that makes either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes a gene product with a novel function or expression pattern compared to wild-type.
djs93
2010-09-06T04:03:33Z
allele_class
neomorph
FBcv:0000697
neomorphic allele
An allele that makes a gene product with a novel function or expression pattern compared to wild-type.
FlyBase:FBrf0002371
FlyBase:FBrf0049147
A phenotype that is a disruption in the wild-type pattern of segments or parasegments of the embryo or larva.
phenotypic_class
FBcv:0000698
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
embryonic/larval segmentation phenotype
A phenotype that is a disruption in the wild-type pattern of segments or parasegments of the embryo or larva.
FlyBase:FBrf0035438
Embryonic/larval segmentation phenotype that is the complete or partial loss of alternate segments or parasegments.
phenotypic_class
FBcv:0000699
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
pair rule phenotype
Embryonic/larval segmentation phenotype that is the complete or partial loss of alternate segments or parasegments.
FlyBase:FBrf0035438
Embryonic/larval segmentation phenotype that is the complete or partial loss of even segments.
phenotypic_class
FBcv:0000700
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
even pair-rule phenotype
Embryonic/larval segmentation phenotype that is the complete or partial loss of even segments.
FlyBase:FBrf0035438
Embryonic/larval segmentation phenotype that is the complete or partial loss of odd segments.
phenotypic_class
FBcv:0000701
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
odd pair-rule phenotype
Embryonic/larval segmentation phenotype that is the complete or partial loss of odd segments.
FlyBase:FBrf0035438
Embryonic/larval segmentation phenotype in which some fraction of each segment (along the anterior-posterior axis) is deleted and replaced by a mirror image duplication of the remaining part of the segment.
phenotypic_class
FBcv:0000702
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
segment polarity phenotype
Embryonic/larval segmentation phenotype in which some fraction of each segment (along the anterior-posterior axis) is deleted and replaced by a mirror image duplication of the remaining part of the segment.
FlyBase:FBrf0035438
Embryonic/larval segmentation phenotype that is the complete loss of a contiguous stretch of 2 or more segments.
phenotypic_class
FBcv:0000703
Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
gap phenotype
Embryonic/larval segmentation phenotype that is the complete loss of a contiguous stretch of 2 or more segments.
FlyBase:FBrf0035438
Phenotype expressed only in the presence or absence of some specific chemical whose presence or absence does not induce the same defect in wild-type animals.
djs93
2010-09-20T11:13:19Z
environmental_qualifier
FBcv:0000704
chemical conditional
Phenotype expressed only in the presence or absence of some specific chemical whose presence or absence does not induce the same defect in wild-type animals.
FBC:DOS
Phenotype that is a defect in sleep (GO:0030431). 'sleep' is defined as: 'Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.'
djs93
2010-09-20T12:06:13Z
phenotypic_class
FBcv:0000705
sleep defective
Phenotype that is a defect in sleep (GO:0030431). 'sleep' is defined as: 'Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.'
FBC:DOS
ISBN:0192800981
Phenotype that is a defect in entry into diapause (GO:0055115). 'entry into diapause' is defined as: 'The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.'
djs93
2010-09-20T12:06:28Z
phenotypic_class
FBcv:0000706
diapause defective
Phenotype that is a defect in entry into diapause (GO:0055115). 'entry into diapause' is defined as: 'The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.'
FBC:DOS
GOC:ds
GOC:jid
GOC:mah
Phenotype that is a defect in entry into reproductive diapause (GO:0055116). 'entry into reproductive diapause' is defined as: 'The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.'
djs93
2010-09-20T12:21:29Z
phenotypic_class
FBcv:0000707
reproductive diapause defective
Phenotype that is a defect in entry into reproductive diapause (GO:0055116). 'entry into reproductive diapause' is defined as: 'The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.'
FBC:DOS
GOC:ds
GOC:jid
GOC:mah
Phenotype that is a defect in response to starvation (GO:0042594). 'response to starvation' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.'
phenotypic_class
FBcv:0000708
starvation stress response defective
Phenotype that is a defect in response to starvation (GO:0042594). 'response to starvation' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.'
FBC:DOS
GOC:go_curators
Phenotype that is an increase or decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by defects in cell growth - there may be a greater or lesser number of cells in an otherwise normal volume of tissue.
phenotypic_class
FBcv:0000709
cell number defective
Phenotype that is an increase or decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by defects in cell growth - there may be a greater or lesser number of cells in an otherwise normal volume of tissue.
FBC:DOS
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double stranded break in an engineered donor construct that contains sequence homologous to the target gene.
change induced by gene targeting via homologous recombination
origin_of_mutation
FBcv:0000710
Strictly, homologous recombinational repair (GO:0000724) defines only the endogenous process, not its use for engineered gene targeting.
gene targeting by homologous recombination
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double stranded break in an engineered donor construct that contains sequence homologous to the target gene.
FBC:MC
FlyBase:FBrf0202435
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break on both sides of the homologous region in an engineered donor sequence. This double-strand break is usually generated by cutting at a single site adjacent to the homologous region in a circularized donor sequence. This typically generates a simple targeted replacement of the target sequence by the donor sequence. However, more complicated outcomes are possible.
change induced by ends-out gene targeting
origin_of_mutation
FBcv:0000711
ends-out gene targeting
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break on both sides of the homologous region in an engineered donor sequence. This double-strand break is usually generated by cutting at a single site adjacent to the homologous region in a circularized donor sequence. This typically generates a simple targeted replacement of the target sequence by the donor sequence. However, more complicated outcomes are possible.
FBC:MC
FlyBase:FBrf0167363
FlyBase:FBrf0202435
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break within an engineered homologous donor sequence. This typically generates a tandem duplication of the homologous sequence from the donor, separated by the remainder of the incoming donor DNA. However, more complicated outcomes are possible.
change induced by ends-in gene targeting
origin_of_mutation
FBcv:0000712
ends-in gene targeting
Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break within an engineered homologous donor sequence. This typically generates a tandem duplication of the homologous sequence from the donor, separated by the remainder of the incoming donor DNA. However, more complicated outcomes are possible.
FBC:MC
FlyBase:FBrf0167363
FlyBase:FBrf0202435
Phenotype that is a inability to jump. This may be due to neurological or muscular defects.
djs93
2011-03-10T04:57:06Z
phenotypic_class
FBcv:0000713
jumpless
Phenotype that is a inability to jump. This may be due to neurological or muscular defects.
FBC:DOS
Phenotype only expressed under some specific nutritional regime.
djs93
2011-01-14T12:34:01Z
environmental_qualifier
FBcv:0000714
nutrition conditional
Phenotype only expressed under some specific nutritional regime.
FBC:DOS
Phenotype only expressed under conditions where calorie intake is restricted.
djs93
2011-01-14T05:12:37Z
environmental_qualifier
FBcv:0000715
calorie restriction conditional
Phenotype only expressed under conditions where calorie intake is restricted.
FBC:DOS
Phenotype that is a defect in cell migration (GO:0016477). 'cell migration' is defined as: 'The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.'
phenotypic_class
FBcv:0000716
cell migration defective
Phenotype that is a defect in cell migration (GO:0016477). 'cell migration' is defined as: 'The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.'
FBC:DOS
GOC:cjm
GOC:dph
GOC:ems
GOC:pf
Wikipedia:Cell_migration
Phenotype that is an increase in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
phenotypic_class
FBcv:0000717
increased cell growth
Phenotype that is an increase in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is an decrease in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
phenotypic_class
FBcv:0000718
decreased cell growth
Phenotype that is an decrease in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
FBC:DOS
Phenotype that is a decrease in size of an initially normally sized organ or tissue due to wasting away of cells.
djs93
2011-03-10T05:59:04Z
phenotypic_class
FBcv:0000719
atrophy
Phenotype that is a decrease in size of an initially normally sized organ or tissue due to wasting away of cells.
FBC:DOS
Phenotype that is a defect or in or absence of a jump response (GO:0007630). The jump response in Drosophila is a reflex escape response that can be triggered by a number of signals including odor and light. Standard assays are commonly used to test odor and light induced jump response.
djs93
2011-03-11T08:03:28Z
phenotypic_class
FBcv:0000720
jump response defective
Phenotype that is a defect or in or absence of a jump response (GO:0007630). The jump response in Drosophila is a reflex escape response that can be triggered by a number of signals including odor and light. Standard assays are commonly used to test odor and light induced jump response.
FlyBase:FBrf0187887
FlyBase:FBrf0191819
Phenotype that is a defect in mating behavior (GO:0007617). 'mating behavior' is defined as: 'The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.'
phenotypic_class
FBcv:0000721
mating behavior defective
Phenotype that is a defect in mating behavior (GO:0007617). 'mating behavior' is defined as: 'The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.'
FBC:DOS
GOC:ai
GOC:dph
A clone of somatic cells that share a mutant genotype that includes being Minute +/+ and that is part of and derived from an animal with a different genotype that includes being Minute +/-.
djs93
2011-01-27T04:55:28Z
clone_qualifier
FBcv:0000722
somatic clone - Minute background
A clone of somatic cells that share a mutant genotype that includes being Minute +/+ and that is part of and derived from an animal with a different genotype that includes being Minute +/-.
FBC:DOS
Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form.
phenotypic_class
FBcv:0000723
neoplasia
Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form.
FBC:DOS
Phenotype that is a reduction in size of an organ or tissue compared to wild-type due to reduced numbers of cells being produced during its development or growth.
phenotypic_class
FBcv:0000724
This term should not be used where an organ or tissue is reduced in size due to the wasting away of existing cells.
hypoplasia
Phenotype that is a reduction in size of an organ or tissue compared to wild-type due to reduced numbers of cells being produced during its development or growth.
FBC:DOS
Phenotype that is a defect in response to oxidative stress (GO:0006979). 'response to oxidative stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.'
phenotypic_class
FBcv:0000725
oxidative stress response defective
Phenotype that is a defect in response to oxidative stress (GO:0006979). 'response to oxidative stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.'
FBC:DOS
GOC:jl
PMID:12115731
Expressed in virgin females.
djs93
2011-04-21T01:10:32Z
sex_qualifier
FBcv:0000726
May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin females.
virgin female
Expressed in virgin females.
FBC:DOS
Expressed in mated females.
djs93
2011-04-21T01:10:49Z
sex_qualifier
FBcv:0000727
May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females.
mated female
Expressed in mated females.
FBC:DOS
Expressed in virgin males.
djs93
2011-04-21T01:11:13Z
sex_qualifier
FBcv:0000728
May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin males.
virgin male
Expressed in virgin males.
FBC:DOS
Expressed in mated males.
djs93
2011-04-21T01:11:21Z
sex_qualifier
FBcv:0000729
May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females.
mated male
Expressed in mated males.
FBC:DOS
Expression is limited to virgin females.
djs93
2011-04-21T01:11:46Z
sex_qualifier
FBcv:0000730
May be used to qualify expression of phenotypes or of genes, transgenes etc.
virgin female limited
Expression is limited to virgin females.
FBC:DOS
Expression is limited to mated females.
djs93
2011-04-21T01:11:59Z
sex_qualifier
FBcv:0000731
May be used to qualify expression of phenotypes or of genes, transgenes etc.
mated female limited
Expression is limited to mated females.
FBC:DOS
Expression is limited to mated males.
djs93
2011-04-21T01:12:14Z
sex_qualifier
FBcv:0000732
May be used to qualify expression of phenotypes or of genes, transgenes etc.
mated male limited
Expression is limited to mated males.
FBC:DOS
Expression is limited to virgin males.
djs93
2011-04-21T01:13:00Z
sex_qualifier
FBcv:0000733
May be used to qualify expression of phenotypes or of genes, transgenes etc.
virgin male limited
Expression is limited to virgin males.
FBC:DOS
Embryonic/larval segmentation phenotype that is the complete or partial loss of terminal regions of the embryo/larva: the acron, telson and immediately adjacent segments.
djs93
2011-09-13T02:31:53Z
phenotypic_class
FBcv:0000734
terminal phenotype
Embryonic/larval segmentation phenotype that is the complete or partial loss of terminal regions of the embryo/larva: the acron, telson and immediately adjacent segments.
FBC:DOS
A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
mutation induced by N-nitrosodiethylamine exposure
origin_of_mutation
NDEA
FBcv:0000735
N-nitrosodiethylamine
A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
CHEBI:34873
NDEA
FlyBase:FBrf0139766
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at high temperatures, but that retains at least some function at lower temperatures.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000736
heat sensitive amorphic allele
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at high temperatures, but that retains at least some function at lower temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to completely lack function at some temperatures (restrictive temperatures) but not others (permissive temperatures) from the observation that addition of extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000737
temperature conditional amorphic allele - genetic evidence
An allele inferred to completely lack function at some temperatures (restrictive temperatures) but not others (permissive temperatures) from the observation that addition of extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
A publication that is not issued on a regular, ongoing basis containing separate articles or chapters (typically reviews) written by different authors on a single subject or related subjects, overseen by one or more editors.
djs93
2012-07-10T04:05:08Z
pub_type
FBcv:0000738
edited book
A publication that is not issued on a regular, ongoing basis containing separate articles or chapters (typically reviews) written by different authors on a single subject or related subjects, overseen by one or more editors.
FBC:SM
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at some temperatures, but not others.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000739
temperature conditional amorphic allele
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at some temperatures, but not others.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000740
cold sensitive amorphic allele - genetic evidence
An allele inferred to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000741
heat sensitive amorphic allele - genetic evidence
An allele inferred to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures).
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000742
cold sensitive amorphic allele - molecular evidence
An allele shown by molecular evidence to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures).
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures).
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000743
heat sensitive amorphic allele - molecular evidence
An allele shown by molecular evidence to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures).
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to completely lack function at some temperatures (restrictive temperatures) but not at others (permissive temperatures).
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000744
temperature conditional amorphic allele - molecular evidence
An allele shown by molecular evidence to completely lack function at some temperatures (restrictive temperatures) but not at others (permissive temperatures).
FBC:DOS
FlyBase:FBrf0049147
An allele that at some temperatures but not others either makes no functional gene product or makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000745
temperature conditional loss of function allele
An allele that at some temperatures but not others either makes no functional gene product or makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that at high temperatures but not low temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000746
heat sensitive loss of function allele
An allele that at high temperatures but not low temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that at low temperatures but not high temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
allele_class
FBcv:0000747
cold sensitive loss of function allele
An allele that at low temperatures but not high temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that at some temperatures but not others, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000748
temperature conditional gain of function allele
An allele that at some temperatures but not others, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that at high temperatures but not low temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000749
heat sensitive gain of function allele
An allele that at high temperatures but not low temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that at low temperatures but not high temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
allele_class
FBcv:0000750
cold sensitive gain of function allele
An allele that at low temperatures but not high temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type.
FBC:DOS
FlyBase:FBrf0049147
An allele that, at some temperatures but not others, makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000751
temperature conditional hypomorphic allele
An allele that, at some temperatures but not others, makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes a gene product that is functionally equivalent to wild-type but which at high temperatures is present in a lesser amount or with lowered activity, and that retains normal levels of expression or activity at low temperatures.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000752
heat sensitive hypomorphic allele
An allele that makes a gene product that is functionally equivalent to wild-type but which at high temperatures is present in a lesser amount or with lowered activity, and that retains normal levels of expression or activity at low temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes a gene product that is functionally equivalent to wild-type but which at low temperatures is present in a lesser amount or with lowered activity, and that retains normal function at higher temperatures.
allele_class
FBcv:0000753
cold sensitive hypomorphic allele
An allele that makes a gene product that is functionally equivalent to wild-type but which at low temperatures is present in a lesser amount or with lowered activity, and that retains normal function at higher temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000754
temperature conditional hypomorphic allele - genetic evidence
An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to have normal activity at high temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at lower temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000755
cold sensitive hypomorphic allele - genetic evidence
An allele inferred from genetic evidence to have normal activity at high temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at lower temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to have normal activity at low temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at higher temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000756
heat sensitive hypomorphic allele - genetic evidence
An allele inferred from genetic evidence to have normal activity at low temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at higher temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy)).
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a normal gene product in normal amounts at some temperatures, but at other temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000757
temperature conditional hypomorphic allele - molecular evidence
An allele shown by molecular evidence to make a normal gene product in normal amounts at some temperatures, but at other temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a normal gene product in normal amounts at high temperatures, but at lower temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000758
cold sensitive hypomorphic allele - molecular evidence
An allele shown by molecular evidence to make a normal gene product in normal amounts at high temperatures, but at lower temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a normal gene product in normal amounts at low temperatures, but at higher temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000759
heat sensitive hypomorphic allele - molecular evidence
An allele shown by molecular evidence to make a normal gene product in normal amounts at low temperatures, but at higher temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity.
FBC:DOS
FlyBase:FBrf0049147
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at some temperatures, but not others.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000760
temperature conditional antimorphic allele
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at some temperatures, but not others.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at high temperatures, but not at lower temperatures.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000761
heat sensitive antimorphic allele
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at high temperatures, but not at lower temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at cold temperatures, but not at higher temperatures.
allele_class
FBcv:0000762
cold sensitive antimorphic allele
An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at cold temperatures, but not at higher temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at some temperatures (restrictive temperatures) but not at others (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000763
temperature conditional antimorphic allele - genetic evidence
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at some temperatures (restrictive temperatures) but not at others (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000764
cold sensitive antimorphic allele - genetic evidence
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at high temperatures (restrictive temperatures) but not at lower temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000765
heat sensitive antimorphic allele - genetic evidence
An allele inferred to make a gene product that is antagonistic to the wild-type gene product at high temperatures (restrictive temperatures) but not at lower temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at some temperatures but not others.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000766
temperature conditional antimorphic allele - molecular evidence
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at some temperatures but not others.
FBC:DOS
FlyBase:FBrf0049147
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at low temperatures but not higher temperatures.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000767
cold sensitive antimorphic allele - molecular evidence
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at low temperatures but not higher temperatures.
FBC:DOS
FlyBase:FBrf0049147
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at high temperatures but not lower temperatures.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000768
heat sensitive antimorphic allele - molecular evidence
An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at high temperatures but not lower temperatures.
FBC:DOS
FlyBase:FBrf0049147
An allele that, at some temperatures but not others, makes a gene product with a novel function or expression pattern compared to wild-type.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000769
temperature conditional neomorphic allele
An allele that, at some temperatures but not others, makes a gene product with a novel function or expression pattern compared to wild-type.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, at some high temperatures but not lower temperatures, makes a gene product with a novel function or expression pattern compared to wild-type.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000770
heat sensitive neomorphic allele
An allele that, at some high temperatures but not lower temperatures, makes a gene product with a novel function or expression pattern compared to wild-type.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, at some low temperatures but not higher temperatures, makes a gene product at with a novel function or expression pattern compared to wild-type.
allele_class
FBcv:0000771
cold sensitive neomorphic allele
An allele that, at some low temperatures but not higher temperatures, makes a gene product at with a novel function or expression pattern compared to wild-type.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some temperatures (non-permissive temperatures) but not others (permissive temperatures) based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000772
temperature conditional neomorphic allele - genetic evidence
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some temperatures (non-permissive temperatures) but not others (permissive temperatures) based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000773
cold sensitive neomorphic allele - genetic evidence
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000774
heat sensitive neomorphic allele - genetic evidence
An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at some temperatures but not others.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000775
temperature conditional neomorphic allele - molecular evidence
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at some temperatures but not others.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at low temperatures but not higher temperatures.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000776
cold sensitive neomorphic allele - molecular evidence
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at low temperatures but not higher temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at high temperatures but not lower temperatures.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000777
heat sensitive neomorphic allele - molecular evidence
An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at high temperatures but not lower temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, at some temperatures but not others, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.
djs93
2012-03-22T03:57:02Z
allele_class
FBcv:0000778
temperature conditional hypermorphic allele
An allele that, at some temperatures but not others, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, at high temperatures but not lower temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.
djs93
2012-03-22T03:54:34Z
allele_class
FBcv:0000779
heat sensitive hypermorphic allele
An allele that, at high temperatures but not lower temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele that, at low temperatures but not higher temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type..
allele_class
FBcv:0000780
cold sensitive hypermorphic allele
An allele that, at low temperatures but not higher temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type..
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at some temperatures (non-permissive temperatures) but not others (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000781
temperature conditional hypermorphic allele - genetic evidence
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at some temperatures (non-permissive temperatures) but not others (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000782
cold sensitive hypermorphic allele - genetic evidence
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000783
heat sensitive hypermorphic allele - genetic evidence
An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at some temperatures but not others.
djs93
2012-03-22T03:55:17Z
allele_class
FBcv:0000784
temperature conditional hypermorphic allele - molecular evidence
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at some temperatures but not others.
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at low temperatures but not higher temperatures.
djs93
2012-03-22T03:58:31Z
allele_class
FBcv:0000785
cold sensitive hypermorphic allele - molecular evidence
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at low temperatures but not higher temperatures.
FBC:DOS
FlyBase:FBrf0049147
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at high temperatures but not lower temperatures.
djs93
2012-03-22T03:59:43Z
allele_class
FBcv:0000786
heat sensitive hypermorphic allele - molecular evidence
An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at high temperatures but not lower temperatures.
FBC:DOS
FlyBase:FBrf0049147
A publication issued on a regular, ongoing basis containing separate research articles and other writings such as reviews, comments and conference reports.
djs93
2012-07-10T04:08:06Z
MeSH:D020492
pub_type
Periodicals
FBcv:0000787
journal
A publication issued on a regular, ongoing basis containing separate research articles and other writings such as reviews, comments and conference reports.
FBC:SM
MeSH:D020492
Periodicals
MeSH:D020492
A work consisting of a news item appearing in a general-interest newspaper or other general news periodical, containing information of current and timely interest in the field of medicine or science.
djs93
2012-07-10T04:17:34Z
MeSH:D018431
pub_type
FBcv:0000788
newspaper article
A work consisting of a news item appearing in a general-interest newspaper or other general news periodical, containing information of current and timely interest in the field of medicine or science.
FBC:SM
MeSH:D018431
A record of a nucleotide or protein sequence in some standard format.
djs93
2012-07-10T05:42:47Z
pub_type
FBcv:0000789
sequence record
A record of a nucleotide or protein sequence in some standard format.
FBC:SM
Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means.
djs93
2012-07-13T02:06:57Z
MeSH:D019991
pub_type
FBcv:0000790
database
Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means.
FBC:SM
MeSH:D019991
A phenotype in which the aging process (GO:0007568) is slower than in wild-type.
phenotypic_class
FBcv:0000791
delayed aging
A phenotype in which the aging process (GO:0007568) is slower than in wild-type.
FBC:DOC
A phenotype in which the aging process (GO:0007568) is accelerated compared to wild-type.
phenotypic_class
FBcv:0000792
premature aging
A phenotype in which the aging process (GO:0007568) is accelerated compared to wild-type.
FBC:DOC
An adult phenotype that becomes more severe with age.
djs93
2012-10-10T12:02:35Z
temporal_qualifier
FBcv:0000793
progressive
An adult phenotype that becomes more severe with age.
FBC:DOS
Cell autonomy statements describe the cellular focus of mutant phenotype, generally revealed by genetic mosaic analysis, in terms of whether the mutant has its phenotypic effect limited to, or not limited to, cells of the mutant genotype.
genotype_to_phenotype_relation
FBcv:0000797
cell autonomy qualifier
Cell autonomy statements describe the cellular focus of mutant phenotype, generally revealed by genetic mosaic analysis, in terms of whether the mutant has its phenotypic effect limited to, or not limited to, cells of the mutant genotype.
FBC:rd
FlyBase miscellaneous CV
FBcv:0000799
gene descriptor
true
FlyBase miscellaneous CV
FBcv:0000801
polymorphism assay
true
FlyBase miscellaneous CV
restriction fragment length polymorphism
FBcv:0000803
RFLP
true
FlyBase miscellaneous CV
FBcv:0000805
DNA sequence variant
true
Descriptor that relates to aspects of an allele.
FlyBase miscellaneous CV
FBcv:0000807
allele descriptor
Descriptor that relates to aspects of an allele.
FBC:MMC
Qualifier that describes an observable phenotype.
FlyBase miscellaneous CV
FBcv:0000809
phenotype qualifier
Qualifier that describes an observable phenotype.
FBC:MMC
Qualifier that describes a particular quality of an observable phenotype.
FlyBase miscellaneous CV
FBcv:0000811
qualitative qualifier
Qualifier that describes a particular quality of an observable phenotype.
FBC:MMC
A clone of cells that share a genotype.
clone_qualifier
clone qualifier
FBcv:0000812
clone of cells
A clone of cells that share a genotype.
FBC:DOS
Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
mutation induced by nitrogen mustard exposure
origin_of_mutation
2-chloro-N-(2-chloroethyl)-N-methylethanamine
CB1414
HN2
mechlorethamine
FBcv:0000813
nitrogen mustard
Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR.
CHEBI:37598
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
mutation induced by 1,4-dimethanesulfonoxybutane exposure
mutation induced by busulfan exposure
origin_of_mutation
CB2041
busulfan
FBcv:0000814
1,4-dimethanesulfonoxybutane
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
CHEBI:28901
busulfan
CHEBI:28901
A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
chlorambucil
mutation induced by chlorambucil exposure
mutation induced by p-N,N-di-(2-chloroethyl)aminophenylbutyric acid exposure
origin_of_mutation
CB1348
FBcv:0000815
p-N,N-di-(2-chloroethyl)aminophenylbutyric acid
A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
CHEBI:28830
chlorambucil
CHEBI:28830
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at low temperatures, but that retains at least some function at higher temperatures.
FlyBase miscellaneous CV
FBcv:0001003
cold sensitive amorphic allele
An allele that completely lacks function (i.e. whose gene productive is completely inactive) at low temperatures, but that retains at least some function at higher temperatures.
FBC:DOS
FlyBase:FBrf0002371
FlyBase:FBrf0049147
Phenotype expressed only in the presence of beta-estradiol (CHEBI:16469).
conditional beta-estradiol
environmental_qualifier
FBcv:0001315
beta-estradiol conditional
Phenotype expressed only in the presence of beta-estradiol (CHEBI:16469).
FBC:DOS
Phenotype that is a defect in endocytosis (GO:0006897). 'endocytosis' is defined as: 'A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.'
phenotypic_class
FBcv:0001324
endocytosis defective
Phenotype that is a defect in endocytosis (GO:0006897). 'endocytosis' is defined as: 'A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.'
FBC:DOS
GOC:mah
ISBN:0198506732
ISBN:0716731363
Phenotype that is a defect in exocytosis (GO:0006887). 'exocytosis' is defined as: 'A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.'
phenotypic_class
FBcv:0001325
exocytosis defective
Phenotype that is a defect in exocytosis (GO:0006887). 'exocytosis' is defined as: 'A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.'
GOC:mah
ISBN:0716731363
PMID:22323285
A defect in or loss of some anatomical structure or biological process compared to wild-type.
phenotypic class
phenotypic_class
FBcv:0001347
The subclasses of this term classify Drosophila phenotypes into different common categories. They have been chosen by FlyBase to reflect phenotype terms most often reported by Drosophila researchers in the published literature.
phenotype
A defect in or loss of some anatomical structure or biological process compared to wild-type.
FBC:DOS
Mutation induced by the transposable activity caused by Minos, a DNA transposable element. The minos element is 1.4 kilobases in length with 254 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of 2 base pairs upon insertion. Mobilization is induced by the activity of the minos transposase.
mutation induced by minos activity
origin_of_mutation
FBcv:0001500
minos activity
Mutation induced by the transposable activity caused by Minos, a DNA transposable element. The minos element is 1.4 kilobases in length with 254 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of 2 base pairs upon insertion. Mobilization is induced by the activity of the minos transposase.
FBC:DOS
FlyBase:FBrf0202435
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to eclosion from the pupal case (the end of the P-stage).
lethal - all die before end of pharate adult stage
phenotypic_class
As the P-Stage and the 'pharate adult stage' have the same end, there is no need for a separate term for 'lethal - all die before end of pharate adult stage.
lethal - all die before end of P-stage
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to eclosion from the pupal case (the end of the P-stage).
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the first instar larval stage.
phenotypic_class
lethal - all die before end of first instar larval stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the first instar larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the larval stage.
lethal - all die before end of third instar larval stage
phenotypic_class
As the larval stage and third instar larval stage have the same end, there is no need for a separate term for 'lethal - all die before end of third instar larval stage'.
lethal - all die before end of larval stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the second instar larval stage.
phenotypic_class
lethal - all die before end of second instar larval stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the second instar larval stage.
FBC:DOS
A phenotype that is an increase in the rate of death in a population at any stage of life (during development or adulthood), over the rate seen in a wild type control population.
phenotypic_class
increased mortality
A phenotype that is an increase in the rate of death in a population at any stage of life (during development or adulthood), over the rate seen in a wild type control population.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the P-stage.
phenotypic_class
lethal - all die during P-stage
A phenotype of a population that is the death of all animals in that population during the P-stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the first instar larval stage.
phenotypic_class
lethal - all die during first instar larval stage
A phenotype of a population that is the death of all animals in that population during the first instar larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the larval stage.
phenotypic_class
lethal - all die during larval stage
A phenotype of a population that is the death of all animals in that population during the larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the second instar larval stage.
phenotypic_class
lethal - all die during second instar larval stage
A phenotype of a population that is the death of all animals in that population during the second instar larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the third instar larval stage.
phenotypic_class
lethal - all die during third instar larval stage
A phenotype of a population that is the death of all animals in that population during the third instar larval stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the P-stage.
phenotypic_class
majority die during P-stage
A phenotype of a population that is the death of the majority of animals in that population during the P-stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the first instar larval stage.
phenotypic_class
majority die during first instar larval stage
A phenotype of a population that is the death of the majority of animals in that population during the first instar larval stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the larval stage.
phenotypic_class
majority die during larval stage
A phenotype of a population that is the death of the majority of animals in that population during the larval stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the second instar larval stage.
phenotypic_class
majority die during second instar larval stage
A phenotype of a population that is the death of the majority of animals in that population during the second instar larval stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the third instar larval stage.
phenotypic_class
majority die during third instar larval stage
A phenotype of a population that is the death of the majority of animals in that population during the third instar larval stage.
FBC:DOS
A phenotype of a population that is the death of some significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
phenotypic_class
partially lethal
A phenotype of a population that is the death of some significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
FBC:KM
A phenotype of a population that is the death of a significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
phenotypic_class
increased mortality during development
A phenotype of a population that is the death of a significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the P-stage.
phenotypic_class
some die during P-stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the P-stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the first instar larval stage.
phenotypic_class
some die during first instar larval stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the first instar larval stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the second instar larval stage.
phenotypic_class
some die during second instar larval stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the second instar larval stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the larval stage.
phenotypic_class
some die during larval stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the larval stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the third instar larval stage.
phenotypic_class
some die during third instar larval stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the third instar larval stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the pharate adult stage.
phenotypic_class
lethal - all die during pharate adult stage
A phenotype of a population that is the death of all animals in that population during the pharate adult stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the prepupal stage.
phenotypic_class
lethal - all die before end of prepupal stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the prepupal stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the pupal stage.
phenotypic_class
lethal - all die before end of pupal stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the pupal stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the pupal stage.
phenotypic_class
lethal - all die during pupal stage
A phenotype of a population that is the death of all animals in that population during the pupal stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the prepupal stage.
phenotypic_class
lethal - all die during prepupal stage
A phenotype of a population that is the death of all animals in that population during the prepupal stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the embryonic stage.
phenotypic_class
lethal - all die before end of embryonic stage
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the embryonic stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population during the embryonic stage.
phenotypic_class
lethal - all die during embryonic stage
A phenotype of a population that is the death of all animals in that population during the embryonic stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the pupal stage.
phenotypic_class
majority die during pupal stage
A phenotype of a population that is the death of the majority of animals in that population during the pupal stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the prepupal stage.
phenotypic_class
majority die during prepupal stage
A phenotype of a population that is the death of the majority of animals in that population during the prepupal stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the pharate adult stage.
phenotypic_class
majority die during pharate adult stage
A phenotype of a population that is the death of the majority of animals in that population during the pharate adult stage.
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population during the embryonic stage.
phenotypic_class
This term is agnostic about whether any survive to adulthood.
majority die during embryonic stage
A phenotype of a population that is the death of the majority of animals in that population during the embryonic stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the pharate adult stage.
phenotypic_class
some die during pharate adult stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the pharate adult stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the pupal stage.
phenotypic_class
some die during pupal stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the pupal stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the prepupal stage.
phenotypic_class
some die during prepupal stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the prepupal stage.
FBC:DOS
A phenotype of a population that is the death of a significant proportion of animals in that population during the embryonic stage.
phenotypic_class
some die during embryonic stage
A phenotype of a population that is the death of a significant proportion of animals in that population during the embryonic stage.
FBC:DOS
A phenotype of a population that is the death of all animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
phenotypic_class
lethal - all die during immature adult stage
A phenotype of a population that is the death of all animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
FBC:DOS
A phenotype of a population that is the death of the majority of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
phenotypic_class
majority die during immature adult stage
A phenotype of a population that is the death of the majority of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
FBC:DOS
A phenotype of a population that is the death of some significant number of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
phenotypic_class
some die during immature adult stage
A phenotype of a population that is the death of some significant number of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
FBC:DOS
Qualifier that describes aspects of genetic models of disease.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003000
disease qualifier
Qualifier that describes aspects of genetic models of disease.
FBC:MMC
Makes a condition better.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003001
The 'ameliorates' term is used in FlyBase disease annotation when an allele interacts to remove or reduce the severity of the disease phenotype associated with a given disease model (FBC:ST).
ameliorates
Makes a condition better.
FBC:ST
Contrary to expectation, does not make a condition better.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003002
The 'DOES NOT ameliorate' term is used in FlyBase disease annotation when an allele is expected to remove or reduce the severity of the disease phenotype associated with a given disease model but fails to do so.
DOES NOT ameliorate
Contrary to expectation, does not make a condition better.
FBC:ST
Contrary to expectation, does not make a condition worse.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003003
The 'DOES NOT exacerbate' term is used in FlyBase disease annotation when an allele is expected to makes the disease phenotype associated with a given disease model more severe but fails to do so (FBC:ST).
DOES NOT exacerbate
Contrary to expectation, does not make a condition worse.
FBC:ST
Contrary to expectation, characteristics associated with a given condition are not recapitulated in a different system.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003004
The 'DOES NOT model' term is used in FlyBase disease annotation when an allele is expected to recapitulate one or more aspects of a particular human disease phenotype in Drosophila but fails to do so (FBC:ST).
DOES NOT model
Contrary to expectation, characteristics associated with a given condition are not recapitulated in a different system.
FBC:ST
Makes a condition worse.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003005
The 'exacerbates' term is used in FlyBase disease annotation when an allele interacts to make the disease phenotype associated with a given disease model more severe (FBC:ST).
exacerbates
Makes a condition worse.
FBC:ST
Characteristics associated with a given condition recapitulated in a different system.
mmc46
2014-03-27T11:07:29Z
disease_qualifier
FBcv:0003006
The 'model of' term is used in FlyBase disease annotation when alleles (typically of fly or human genes) recapitulate one or more aspect of a human disease phenotype in Drosophila (FBC:ST).
model of
Characteristics associated with a given condition recapitulated in a different system.
FBC:ST
Sequence change induced by a cleavage event that is caused by an endonuclease that recognizes and cleaves specific sequences in double stranded DNA causing double-strand breaks (DSB).
mmc46
2014-03-27T11:07:29Z
change induced by site specific cleavage
origin_of_mutation
FBcv:0003007
site specific cleavage
Sequence change induced by a cleavage event that is caused by an endonuclease that recognizes and cleaves specific sequences in double stranded DNA causing double-strand breaks (DSB).
FlyBase:FBrf0202435
Sequence change caused by a cleavage of a specific DNA sequence induced by CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 nuclease system. This system relies on the transcription of a chimeric guide RNA (gRNA) which directs the Cas9 endonuclease to a specified DNA sequence through basepairing to 20 nucleotide CRISPR target sites. These sites are located next to a 3 nucleotide protospacer adjacent motif (PAM) required for DNA cleavage.
mmc46
2014-03-27T11:07:29Z
change induced by CRISPR/Cas9 endonuclease cleavage
origin_of_mutation
CRISPR/Cas9 endonuclease
FBcv:0003008
CRISPR/Cas9
Sequence change caused by a cleavage of a specific DNA sequence induced by CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 nuclease system. This system relies on the transcription of a chimeric guide RNA (gRNA) which directs the Cas9 endonuclease to a specified DNA sequence through basepairing to 20 nucleotide CRISPR target sites. These sites are located next to a 3 nucleotide protospacer adjacent motif (PAM) required for DNA cleavage.
FlyBase:FBrf0222128
FlyBase:FBrf0222292
FlyBase:FBrf0222617
UniProt:Q99ZW2
Sequence change caused by the cleavage of specific DNA sequences by transcription activator-like effector nucleases (TALENs). TALEN proteins comprise a DNA binding domain fused to the catalytic domain of the FokI endonuclease. The DNA binding domain contains a repetitive region within the middle of the protein, consisting of tandem repeats of 34 amino acid segments, with each of these segments recognizing a single base pair. The specificity of the binding is determined by two hypervariable amino acids in positions 12 and 13 (repeat-variable diresidues). Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of TALENs which bind to adjacent sequences separated by a spacer region, allowing dimerization and promoting cleavage.
mmc46
2014-03-27T11:07:29Z
change induced by TALE endonuclease cleavage
origin_of_mutation
TALE endonuclease
FBcv:0003009
TALEN
Sequence change caused by the cleavage of specific DNA sequences by transcription activator-like effector nucleases (TALENs). TALEN proteins comprise a DNA binding domain fused to the catalytic domain of the FokI endonuclease. The DNA binding domain contains a repetitive region within the middle of the protein, consisting of tandem repeats of 34 amino acid segments, with each of these segments recognizing a single base pair. The specificity of the binding is determined by two hypervariable amino acids in positions 12 and 13 (repeat-variable diresidues). Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of TALENs which bind to adjacent sequences separated by a spacer region, allowing dimerization and promoting cleavage.
PMID:10954606
PMID:20660643
Sequence change caused by a site specific recombination catalyzed by the serine recombinase phiC31 integrase that recognizes a minimal high-efficiency attP recognition site of 39 base pairs and a minimal high-efficiency attB recognition site of 34 base pairs. The attP and attB sites contain imperfect inverted repeats flanking a short recombination core (TTG) that provides directionality.
mmc46
2014-03-27T11:07:29Z
change induced by phiC31 integrase recombination
origin_of_mutation
FBcv:0003010
phiC31 integrase
Sequence change caused by a site specific recombination catalyzed by the serine recombinase phiC31 integrase that recognizes a minimal high-efficiency attP recognition site of 39 base pairs and a minimal high-efficiency attB recognition site of 34 base pairs. The attP and attB sites contain imperfect inverted repeats flanking a short recombination core (TTG) that provides directionality.
FlyBase:FBrf0174693
FlyBase:FBrf0201927
UniProt:Q9T221
Descriptor that relates aspects of the grouping of genes or gene products.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003011
group descriptor
Descriptor that relates aspects of the grouping of genes or gene products.
FBC:MMC
Genes or gene products that are acknowledged to form a natural biological group.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003012
gene or gene product group
Genes or gene products that are acknowledged to form a natural biological group.
FBC:SM
Two or more genes contiguously arranged where the individual genes are either identical in sequence, or essentially so (SO:0005851).
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003013
gene array group
Two or more genes contiguously arranged where the individual genes are either identical in sequence, or essentially so (SO:0005851).
FBC:SM
SO:ma
Genes whose products share a common biological and/or molecular function.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003014
functional group
Genes whose products share a common biological and/or molecular function.
FBC:SM
Genes with the same location on the chromosome and whose products have a similar function.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003015
gene complex group
Genes with the same location on the chromosome and whose products have a similar function.
FBC:SM
http://www.sdbonline.org/fly/aignfam/ensplitc.htm
Genes whose protein products form a macromolecular complex (GO:0043234).
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003016
protein complex group
Genes whose protein products form a macromolecular complex (GO:0043234).
FBC:SM
GOC:go_curators
Genes whose products act in a specified signal transduction or metabolic pathway.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003017
pathway group
Genes whose products act in a specified signal transduction or metabolic pathway.
FBC:SM
Genes whose products act in a specified biological process.
mmc46
2014-03-28T15:23:42Z
group_descriptor
FBcv:0003018
process group
Genes whose products act in a specified biological process.
FBC:SM
Mutation caused by the transposable activity caused by the I-element, a non-LTR retrotransposon. The I-element is 5371 base pairs long. Mobilization is induced by the activity of the I-element transposase.
mmc46
2014-09-16T13:30:48Z
mutation induced by I-element activity
origin_of_mutation
FBcv:0003019
I-element activity
Mutation caused by the transposable activity caused by the I-element, a non-LTR retrotransposon. The I-element is 5371 base pairs long. Mobilization is induced by the activity of the I-element transposase.
FlyBase:FBrf0202435
Mutation caused by the transposable activity caused by the Stalker element, a LTR retrotransposon. Mobilization is induced by the activity of the stalker element transposase.
mmc46
2014-09-16T13:30:48Z
mutation induced by Stalker element activity
origin_of_mutation
FBcv:0003020
Stalker element activity
Mutation caused by the transposable activity caused by the Stalker element, a LTR retrotransposon. Mobilization is induced by the activity of the stalker element transposase.
FlyBase:FBrf0202435
Term that describes a dataset.
mmc46
2016-02-24T19:19:21Z
FlyBase miscellaneous CV
FBcv:0003021
dataset descriptor
Term that describes a dataset.
FBC:GD
Term that specifies the dataset component type.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003022
dataset entity type
Term that specifies the dataset component type.
FBC:GD
A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003023
project
A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study.
FBC:GD
Biological source material characterized by an experiment.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003024
biosample
Biological source material characterized by an experiment.
FBC:GD
Quantitative or qualitative assessment of biological source material to measure some attribute.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003025
assay
Quantitative or qualitative assessment of biological source material to measure some attribute.
FBC:GD
Analysis of raw data generated by an assay(s) that makes some conclusion.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003026
result
Analysis of raw data generated by an assay(s) that makes some conclusion.
FBC:GD
A collection of material reagents.
mmc46
2016-02-24T19:19:21Z
dataset_entity_type
FBcv:0003027
reagent collection
A collection of material reagents.
FBC:GD
The data type content of a dataset.
mmc46
2016-02-24T19:19:21Z
FlyBase miscellaneous CV
FBcv:0003028
dataset data type
The data type content of a dataset.
FBC:GD
The type of project as characterized its data content.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003029
project type
The type of project as characterized its data content.
FBC:GD
A project that groups together related sub-projects.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003030
umbrella project
A project that groups together related sub-projects.
FBC:GD
A project that characterizes an organism's genome sequence.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003031
genome
A project that characterizes an organism's genome sequence.
FBC:GD
A project that characterizes the intraspecific variation of an organism's genome.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003032
genome variation
A project that characterizes the intraspecific variation of an organism's genome.
FBC:GD
A project that characterizes the occupancy profile of a factor that binds directly or indirectly to the genome.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003033
genome binding
A project that characterizes the occupancy profile of a factor that binds directly or indirectly to the genome.
FBC:GD
A project that characterizes the set of transcribed RNA sequences expressed by the genome.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003034
transcriptome
A project that characterizes the set of transcribed RNA sequences expressed by the genome.
FBC:GD
A project that characterizes the set of proteins expressed in an organism.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003035
proteome
A project that characterizes the set of proteins expressed in an organism.
FBC:GD
A project that characterizes the set of inter-molecular interactions in an organism.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003036
interactome
A project that characterizes the set of inter-molecular interactions in an organism.
FBC:GD
A project that characterizes the set of small molecules in an organism.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003037
metabolome
A project that characterizes the set of small molecules in an organism.
FBC:GD
A project that searches for the genes responsible for a particular observable trait.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003038
phenotypic screen
A project that searches for the genes responsible for a particular observable trait.
FBC:GD
A project that searches for chemicals, natural or synthetic, that elicit some biological effect.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003039
chemical screen
A project that searches for chemicals, natural or synthetic, that elicit some biological effect.
FBC:GD
A project that constructs models describing the set of transcripts and polypeptides encoded by some group of genes.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003040
gene model annotation
A project that constructs models describing the set of transcripts and polypeptides encoded by some group of genes.
FBC:GD
A project that reconstructs the evolutionary history of a group of genes or organisms.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003041
phylogenetic analysis
A project that reconstructs the evolutionary history of a group of genes or organisms.
FBC:GD
A project that describes a large material resource that is accessible to the community.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003042
reagent
A project that describes a large material resource that is accessible to the community.
FBC:GD
A project type that is not described by other more specific terms.
mmc46
2016-02-24T19:19:21Z
project_type
FBcv:0003043
other
A project type that is not described by other more specific terms.
FBC:GD
The type of biosample as characterized by its biological source material.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003044
biosample type
The type of biosample as characterized by its biological source material.
FBC:GD
A biosample that comprises the whole animal.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003045
whole organism
A biosample that comprises the whole animal.
FBC:GD
A biosample derived from a multicellular structure comprising similar cells with some specific function, typically isolated by dissection.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003046
tissue
A biosample derived from a multicellular structure comprising similar cells with some specific function, typically isolated by dissection.
FBC:GD
A biosample containing dissociated cells isolated from the organism, typically isolated by affinity capture or sorting methods.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003047
isolated cells
A biosample containing dissociated cells isolated from the organism, typically isolated by affinity capture or sorting methods.
FBC:GD
A biosample consisting of cells that were isolated from animal tissue and cultured in vitro for a limited amount of time.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003048
primary cell line
A biosample consisting of cells that were isolated from animal tissue and cultured in vitro for a limited amount of time.
FBC:GD
A biosample consisting of cells isolated from animal tissue that have acquired the ability to proliferate indefinitely.
mmc46
2016-02-24T19:19:21Z
biosample_type
FBcv:0003049
immortalized cell line
A biosample consisting of cells isolated from animal tissue that have acquired the ability to proliferate indefinitely.
FBC:GD
The type of assay as characterized by its data content.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003050
assay type
The type of assay as characterized by its data content.
FBC:GD
An assay of 5' capped transcripts, using CAGE to biotinylate and isolate the 7-methylguanosine cap, with subsequent characterization by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003051
CAGE-Seq
An assay of 5' capped transcripts, using CAGE to biotinylate and isolate the 7-methylguanosine cap, with subsequent characterization by high-throughput sequencing.
FBC:GD
A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and analysis of co-purifying DNA fragments using genome tiling array.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003052
ChIP-chip
A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and analysis of co-purifying DNA fragments using genome tiling array.
FBC:GD
A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and high-throughput sequencing of co-purifying DNA fragments.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003053
ChIP-Seq
A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and high-throughput sequencing of co-purifying DNA fragments.
FBC:GD
An RNA binding assay of some protein as characterized by cross-linking immunoprecipitation (CLiP) and high-throughput sequencing of co-purifying RNA fragments.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003054
CLiP-Seq
An RNA binding assay of some protein as characterized by cross-linking immunoprecipitation (CLiP) and high-throughput sequencing of co-purifying RNA fragments.
FBC:GD
A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by genome tiling array.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003055
DamID-chip
A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by genome tiling array.
FBC:GD
A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003056
DamID-Seq
A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by high-throughput sequencing.
FBC:GD
An assay that characterizes the genome's DNase hypersensitivity using genome tiling array.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003057
DNase-chip
An assay that characterizes the genome's DNase hypersensitivity using genome tiling array.
FBC:GD
An assay that characterizes the genome's DNase hypersensitivity using high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003058
DNase-Seq
An assay that characterizes the genome's DNase hypersensitivity using high-throughput sequencing.
FBC:GD
An assay that characterizes transcriptional regulatory elements using formaldehyde-assisted isolation of regulatory elements (FAIRE) and high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003059
FAIRE-Seq
An assay that characterizes transcriptional regulatory elements using formaldehyde-assisted isolation of regulatory elements (FAIRE) and high-throughput sequencing.
FBC:GD
An assay that maps the genome-wide position, orientation and amount of transcriptionally engaged RNA polymerase by global run-on sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003060
GRO-Seq
An assay that maps the genome-wide position, orientation and amount of transcriptionally engaged RNA polymerase by global run-on sequencing.
PMID:19056941
An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by genome tiling array.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003061
MNase-chip
An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by genome tiling array.
FBC:GD
An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003062
MNase-Seq
An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by high-throughput sequencing.
FBC:GD
An assay of 5'-capped transcripts using the orthogonal approaches of reverse transcriptase template-switching and cap-trapping, with subsequent characterization by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003063
RAMPAGE-Seq
An assay of 5'-capped transcripts using the orthogonal approaches of reverse transcriptase template-switching and cap-trapping, with subsequent characterization by high-throughput sequencing.
PMID:22936248
An assay mapping genomic replication patterns by labeling newly synthesized DNA in vivo with 5-bromo-2-deoxyuridine (BrdU), with subsequent affinity purification and characterization by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003064
Repli-Seq
An assay mapping genomic replication patterns by labeling newly synthesized DNA in vivo with 5-bromo-2-deoxyuridine (BrdU), with subsequent affinity purification and characterization by high-throughput sequencing.
PMID:19966280
Ribosome profiling, an assay in which mRNA fragments protected by ribosomes are isolated and characterized by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003065
Ribo-Seq
Ribosome profiling, an assay in which mRNA fragments protected by ribosomes are isolated and characterized by high-throughput sequencing.
PMID:22056041
An assay in which a factor is immunoprecipitated and the associated RNA sequences are characterized by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003066
RIP-Seq
An assay in which a factor is immunoprecipitated and the associated RNA sequences are characterized by high-throughput sequencing.
PMID:21051541
Measurement of global transcript abundance by hybridization of cDNA to an oligonucleotide array, in which the array contains a set of probes designed with complementarity to each annotated transcript.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003067
RNA expression microarray
Measurement of global transcript abundance by hybridization of cDNA to an oligonucleotide array, in which the array contains a set of probes designed with complementarity to each annotated transcript.
FBC:GD
A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003068
RNA-Seq
A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing.
PMID:18451266
Measurement of transcribed regions across the genome by hybridization of cDNA to an oligonucleotide array, in which the genome is represented by oligonucleotides at regularly spaced intervals.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003069
RNA tiling array
Measurement of transcribed regions across the genome by hybridization of cDNA to an oligonucleotide array, in which the genome is represented by oligonucleotides at regularly spaced intervals.
FBC:GD
An assay characterizing of small RNA species 17-35 nt in size by high-throughput sequencing.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003070
short RNA-Seq
An assay characterizing of small RNA species 17-35 nt in size by high-throughput sequencing.
FBC:GD
An assay that identifies and characterizes of proteins and their post-translational modifications by mass spectrometry.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003071
protein mass spectrometry
An assay that identifies and characterizes of proteins and their post-translational modifications by mass spectrometry.
FBC:GD
An assay that identifies and characterizes lipids by mass spectrometry.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003072
lipid mass spectrometry
An assay that identifies and characterizes lipids by mass spectrometry.
FBC:GD
An assay that identifies and characterizes complex carbohydrates by mass spectrometry.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003073
carbohydrate mass spectrometry
An assay that identifies and characterizes complex carbohydrates by mass spectrometry.
FBC:GD
An assay that identifies and characterizes small metabolites by mass spectrometry.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003074
metabolite mass spectrometry
An assay that identifies and characterizes small metabolites by mass spectrometry.
FBC:GD
An assay that identifies the molecules that interact with a particular bait factor by mass spectrometry.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003075
affinity purification and mass spectrometry
An assay that identifies the molecules that interact with a particular bait factor by mass spectrometry.
FBC:GD
An assay that tests proteins pairwise for interaction by fusing each to separate, complementary domains of some protein, usually a transcription factor. Upon interaction, the proximity of the complementary domains generates reporter activity.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003076
two hybrid screen
An assay that tests proteins pairwise for interaction by fusing each to separate, complementary domains of some protein, usually a transcription factor. Upon interaction, the proximity of the complementary domains generates reporter activity.
FBC:GD
An assay that uses a panel of RNA interference (RNAi) reagents to systematically knockdown a large set of genes, one at a time, to identify those that are involved in some biological process.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003077
RNAi screen
An assay that uses a panel of RNA interference (RNAi) reagents to systematically knockdown a large set of genes, one at a time, to identify those that are involved in some biological process.
FBC:GD
An assay that uses a panel of deficiencies to systematically delete large segments of the genome to identify those segments that are involved in some biological process.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003078
deficiency screen
An assay that uses a panel of deficiencies to systematically delete large segments of the genome to identify those segments that are involved in some biological process.
FBC:GD
An assay that uses a large set of mutations to identify genes that are involved in some biological process.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003079
genetic screen
An assay that uses a large set of mutations to identify genes that are involved in some biological process.
FBC:GD
An assay that characterizes copy number variation of the genome in a sample using genome tiling array.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003080
comparative genomic hybridization by array
An assay that characterizes copy number variation of the genome in a sample using genome tiling array.
FBC:GD
An assay of genomic sequence that generates a large number of random genomic sequences, typically derived from paired-end sequencing of genomic fragments, that together give a complete (albeit scrambled) representation of the entire genome.
mmc46
2016-02-24T19:19:21Z
assay_type
FBcv:0003081
whole genome shotgun sequencing
An assay of genomic sequence that generates a large number of random genomic sequences, typically derived from paired-end sequencing of genomic fragments, that together give a complete (albeit scrambled) representation of the entire genome.
FBC:GD
The type of result as characterized by its data content.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003082
result type
The type of result as characterized by its data content.
FBC:GD
A result that maps the relative position of genetic markers, where distances are measured by recombination frequency.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003083
genetic map
A result that maps the relative position of genetic markers, where distances are measured by recombination frequency.
FBC:GD
A result that maps the relative position of genes and other sequence landmarks.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003084
physical map
A result that maps the relative position of genes and other sequence landmarks.
FBC:GD
A result in which a collection of whole genome shotgun sequences is combined to build successively larger contigs.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003085
whole genome shotgun assembly
A result in which a collection of whole genome shotgun sequences is combined to build successively larger contigs.
FBC:GD
The result of reconstruction of the genome achieved by aligning and merging smaller fragments.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003086
genome assembly
The result of reconstruction of the genome achieved by aligning and merging smaller fragments.
FBC:GD
The result of extensive sequence alignment and merging to produce a genome assembly that serves as the current reference for a particular organism.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003087
reference genome assembly
The result of extensive sequence alignment and merging to produce a genome assembly that serves as the current reference for a particular organism.
FBC:GD
A result that provides the expression values for all (or some subset) of genes in a given biological sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003088
gene expression profile
A result that provides the expression values for all (or some subset) of genes in a given biological sample.
FBC:GD
A result that profiles expressed RNA-seq sequences along genome.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003089
RNA-seq profile
A result that profiles expressed RNA-seq sequences along genome.
FBC:GD
A result that profiles the genome occupancy for some factor.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003090
genome binding profile
A result that profiles the genome occupancy for some factor.
FBC:GD
A result of Ribo-seq analysis that profiles ribosome protected sequences along the genome.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003091
mRNA translation profile
A result of Ribo-seq analysis that profiles ribosome protected sequences along the genome.
FBC:GD
An analysis that results in the identification of discrete transcription start site regions.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003092
TSS identification
An analysis that results in the identification of discrete transcription start site regions.
FBC:GD
An analysis that results in the identification of discrete polyadenylation sites.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003093
poly(A) site identification
An analysis that results in the identification of discrete polyadenylation sites.
FBC:GD
An analysis that results in the identification of discrete exon junctions.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003094
exon junction identification
An analysis that results in the identification of discrete exon junctions.
FBC:GD
An analysis that results in the identification of discrete A-to-I RNA editing sites.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003095
editing site identification
An analysis that results in the identification of discrete A-to-I RNA editing sites.
FBC:GD
An analysis that results in the identification of discrete DNA or RNA binding sites.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003096
binding site identification
An analysis that results in the identification of discrete DNA or RNA binding sites.
FBC:GD
An analysis that results from the comparison of expression profiles for different conditions to identify genes that are regulated by those conditions.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003097
differential gene expression analysis
An analysis that results from the comparison of expression profiles for different conditions to identify genes that are regulated by those conditions.
FBC:GD
The analysis of a gene expression profiles to define sets of genes that share similar expression characteristics.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003098
expression clustering
The analysis of a gene expression profiles to define sets of genes that share similar expression characteristics.
FBC:GD
A result that represents a set of genes that share similar expression characteristics across some set of conditions.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003099
expression cluster
A result that represents a set of genes that share similar expression characteristics across some set of conditions.
FBC:GD
A result that represents a set of genes that have some shared characteristic.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003100
gene list
A result that represents a set of genes that have some shared characteristic.
FBC:GD
A result that represents a set of protein-protein interactions for a given sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003101
protein-protein interaction
A result that represents a set of protein-protein interactions for a given sample.
FBC:GD
A result that represents a set of RNA-protein interactions for a given sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003102
RNA-protein interaction
A result that represents a set of RNA-protein interactions for a given sample.
FBC:GD
A result that represents a set of RNA-RNA interactions for a given sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003103
RNA-RNA interaction
A result that represents a set of RNA-RNA interactions for a given sample.
FBC:GD
A result that represents a set of small molecules identified for a given sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003104
metabolite profile
A result that represents a set of small molecules identified for a given sample.
FBC:GD
A result that represents the range of phenotypes obtained for a set of genetic perturbations.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003105
phenotypic profile
A result that represents the range of phenotypes obtained for a set of genetic perturbations.
FBC:GD
A result that represents the copy number variation across the genome for a given sample.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003106
genomic copy number profile
A result that represents the copy number variation across the genome for a given sample.
FBC:GD
A result that represents the mapping of coordinates between two different genome assemblies for a given species.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003107
liftover file
A result that represents the mapping of coordinates between two different genome assemblies for a given species.
FBC:GD
A result that is produced from the detailed examination of data to come to some conclusion.
mmc46
2016-02-24T19:19:21Z
result_type
FBcv:0003108
analysis
A result that is produced from the detailed examination of data to come to some conclusion.
FBC:GD
The type of reagent collection as characterized by the material resources comprised by the collection.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003109
reagent collection type
The type of reagent collection as characterized by the material resources comprised by the collection.
FBC:GD
A collection of large chromosomal aberrations, available as fly stocks, which may include duplications, deletions, inversions or translocations.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003110
aberration stock collection
A collection of large chromosomal aberrations, available as fly stocks, which may include duplications, deletions, inversions or translocations.
FBC:GD
A collection of alleles that are available as fly stocks.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003111
allele collection
A collection of alleles that are available as fly stocks.
FBC:GD
A collection of cDNAs available as plasmids.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003112
cDNA library
A collection of cDNAs available as plasmids.
FBC:GD
A collection of transgenic constructs that are available as fly stocks.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003113
construct collection
A collection of transgenic constructs that are available as fly stocks.
FBC:GD
A collection of PCR products used for the synthesis of double-stranded RNA to induce RNA-interference.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003114
dsRNA amplicon collection
A collection of PCR products used for the synthesis of double-stranded RNA to induce RNA-interference.
FBC:GD
A collection of transgenic constructs, available as fly stocks, designed to target gene knockdown by RNA-interference.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003115
RNAi construct collection
A collection of transgenic constructs, available as fly stocks, designed to target gene knockdown by RNA-interference.
FBC:GD
A collection of genomic DNA clones available as plasmids. This may include BAC, YAC, fosmid, cosmid and P1 clone collections.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003116
genomic clone collection
A collection of genomic DNA clones available as plasmids. This may include BAC, YAC, fosmid, cosmid and P1 clone collections.
FBC:GD
A collection of wild-type fly strains.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003117
fly strain collection
A collection of wild-type fly strains.
FBC:GD
A collection of transgenic construct insertions available as fly stocks.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003118
transgenic insertion collection
A collection of transgenic construct insertions available as fly stocks.
FBC:GD
A collection of transposable element insertions available as fly stocks.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003119
TE insertion stock collection
A collection of transposable element insertions available as fly stocks.
FBC:GD
A collection of hybridization targets on a microarray.
mmc46
2016-02-24T19:19:21Z
reagent_collection_type
FBcv:0003120
microarray library
A collection of hybridization targets on a microarray.
FBC:GD
A descriptor that describes some aspect of a dataset.
mmc46
2016-02-24T19:19:21Z
FlyBase miscellaneous CV
FBcv:0003121
dataset attribute
A descriptor that describes some aspect of a dataset.
FBC:GD
A descriptor that describes some aspect of a project.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003122
project attribute
A descriptor that describes some aspect of a project.
FBC:GD
The aim of the project investigation, as defined by the key variables in the set of experiments.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003123
study design
The aim of the project investigation, as defined by the key variables in the set of experiments.
FBC:GD
A project study design that aims to compare different species.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003124
species study
A project study design that aims to compare different species.
FBC:GD
A project study design that aims to compare different wild-type strains for a given species.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003125
strain study
A project study design that aims to compare different wild-type strains for a given species.
FBC:GD
A project study design that aims to characterize the biological mechanisms responsible for the development or maintenance of the sex-related properties of an organism.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003126
sex study
A project study design that aims to characterize the biological mechanisms responsible for the development or maintenance of the sex-related properties of an organism.
FBC:CT
A project study design investigating the biological mechanisms responsible for the control or maintenance of development.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003127
developmental stage study
A project study design investigating the biological mechanisms responsible for the control or maintenance of development.
FBC:CT
A project study design investigating the biological mechanisms responsible for the control or maintenance of circadian rhythm.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003128
circadian rhythm study
A project study design investigating the biological mechanisms responsible for the control or maintenance of circadian rhythm.
FBC:CT
A project study design investigating the biological mechanisms of the cell responsible for maintaining or controlling aspects of the cell cycle.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003129
cell cycle study
A project study design investigating the biological mechanisms of the cell responsible for maintaining or controlling aspects of the cell cycle.
FBC:CT
A project study design investigating the biological mechanisms of intact or dissected tissues in order to understand their form or function.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003130
tissue type study
A project study design investigating the biological mechanisms of intact or dissected tissues in order to understand their form or function.
FBC:CT
A project study design involving the use of cultured or extracted cells with an investigative focus of studying a cellular property.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003131
cell type study
A project study design involving the use of cultured or extracted cells with an investigative focus of studying a cellular property.
FBC:CT
A project study design examining subcellular components of cells including organelles, the nucleus, or any other grouping of intra- or extracellular material.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003132
subcellular component study
A project study design examining subcellular components of cells including organelles, the nucleus, or any other grouping of intra- or extracellular material.
FBC:CT
A project study design in which the goal of the study is to examine properties of a specific gene or set of genes.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003133
gene study
A project study design in which the goal of the study is to examine properties of a specific gene or set of genes.
FBC:CT
A project study design investigating the effects of a biotic stimulus on some aspect of an organism.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003134
biotic stimulus study
A project study design investigating the effects of a biotic stimulus on some aspect of an organism.
FBC:CT
A project study design investigating the effects of a chemical stimulus on some aspect of an organism.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003135
chemical stimulus study
A project study design investigating the effects of a chemical stimulus on some aspect of an organism.
FBC:CT
A project study design investigating the effects of a physical stimulus on some aspect of an organism.
mmc46
2016-02-24T19:19:21Z
project_attribute
FBcv:0003136
physical stimulus study
A project study design investigating the effects of a physical stimulus on some aspect of an organism.
FBC:CT
Characteristics pertaining to the growth conditions, treatments and tissue isolation methods used to generate and obtain a biosample.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003137
biosample attribute
Characteristics pertaining to the growth conditions, treatments and tissue isolation methods used to generate and obtain a biosample.
FBC:GD
The scope and purity of a biosample, ranging from single cell to environmental sample.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003138
biosample scope
The scope and purity of a biosample, ranging from single cell to environmental sample.
http://www.ncbi.nlm.nih.gov/books/NBK54364/
A biosample that is derived from only a single cell.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003139
single cell sample
A biosample that is derived from only a single cell.
FBC:CT
A biosample that is derived from one individual.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003140
single individual sample
A biosample that is derived from one individual.
FBC:CT
A biosample that is derived from multiple individuals.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003141
multi-individual sample
A biosample that is derived from multiple individuals.
FBC:CT
A biosample that is derived from multiple species.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003142
multispecies sample
A biosample that is derived from multiple species.
FBC:CT
A biosample derived from an environmental sample for which the species content is unknown.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003143
environmental
A biosample derived from an environmental sample for which the species content is unknown.
http://www.ncbi.nlm.nih.gov/books/NBK54364/
A biosample that was synthesized in a laboratory.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003144
artificial
A biosample that was synthesized in a laboratory.
http://www.ncbi.nlm.nih.gov/books/NBK54364/
A sample that originated from a wild caught population and is considered true wild type.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003145
wild caught
A sample that originated from a wild caught population and is considered true wild type.
FBC:CT
Growth conditions and treatments used to culture the organism prior to biosample isolation.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003146
growth condition
Growth conditions and treatments used to culture the organism prior to biosample isolation.
FBC:GD
An inbred strain is subjected to artificial laboratory selection of some trait over the course of several generations.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003147
trait selection
An inbred strain is subjected to artificial laboratory selection of some trait over the course of several generations.
FBC:GD
A sample that is derived from a controlled mating between individuals of two specific species.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003148
interspecific hybrid
A sample that is derived from a controlled mating between individuals of two specific species.
FBC:CT
A sample in which the individuals have undergone mating.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003149
mated
A sample in which the individuals have undergone mating.
FBC:CT
A sample in which the individuals have not undergone mating.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003150
virgin
A sample in which the individuals have not undergone mating.
FBC:CT
A sample that is maintained in conditions comparable to constant darkness.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003151
constant dark
A sample that is maintained in conditions comparable to constant darkness.
FBC:CT
A sample that is maintained in conditions comparable to constant light.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003152
constant light
A sample that is maintained in conditions comparable to constant light.
FBC:CT
A sample that is maintained in conditions with a specific cycle that included exposure to both light and darkness.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003153
light-dark cycle
A sample that is maintained in conditions with a specific cycle that included exposure to both light and darkness.
FBC:CT
A sample that is derived from a primary cell culture.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003154
primary cell culture
A sample that is derived from a primary cell culture.
FBC:CT
Characteristics pertaining to the cell culture conditions used to generate the biosample.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003155
cell culture property
Characteristics pertaining to the cell culture conditions used to generate the biosample.
FBC:GD
A sample that contains a transfected agent which is not incorporated into the genome.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003156
transiently transfected cell line
A sample that contains a transfected agent which is not incorporated into the genome.
FBC:CT
A sample that contains a transfected agent which has been stably incorporated into the genome.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003157
stably transfected cell line
A sample that contains a transfected agent which has been stably incorporated into the genome.
FBC:CT
A sample that is derived from a population of cells undergoing a log phase of division.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003158
log phase cells
A sample that is derived from a population of cells undergoing a log phase of division.
FBC:CT
A sample that is derived from a population of cells undergoing a stationary phase of division.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003159
stationary phase cells
A sample that is derived from a population of cells undergoing a stationary phase of division.
FBC:CT
A sample that is derived from a population of cells undergoing cell cycle division in a synchronized manner.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003160
cell cycle synchronized cells
A sample that is derived from a population of cells undergoing cell cycle division in a synchronized manner.
FBC:CT
The cells that are grown in liquid culture.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003161
suspension culture
The cells that are grown in liquid culture.
FBC:GD
The cells that are grown on plates.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003162
adherent culture
The cells that are grown on plates.
FBC:GD
The conditioned medium containing factors secreted by cultured cells that has been isolated.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003163
culture supernatant
The conditioned medium containing factors secreted by cultured cells that has been isolated.
FBC:GD
Methods pertaining to the experimental treatment or isolation of a biosample.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003164
biosample method
Methods pertaining to the experimental treatment or isolation of a biosample.
FBC:GD
A sample that has undergone a disruption to the activity of one of its genes.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003165
gene perturbation
A sample that has undergone a disruption to the activity of one of its genes.
FBC:GD
Treatment of an organism with a biological stimulus, such as an infectious or parasitic agent.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003166
biotic treatment
Treatment of an organism with a biological stimulus, such as an infectious or parasitic agent.
FBC:GD
A sample that has been exposed to one or more forms of chemical agent.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003167
chemical treatment
A sample that has been exposed to one or more forms of chemical agent.
FBC:CT
A sample that has been exposed to changes in the physical environment including temperature, pressure and radiation.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003168
physical treatment
A sample that has been exposed to changes in the physical environment including temperature, pressure and radiation.
FBC:GD
A sample that has been dissected from the tissue of a more complete organism.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003169
tissue dissection
A sample that has been dissected from the tissue of a more complete organism.
FBC:CT
A single cell type that has been isolated by affinity purification or fluorescent cell sorting.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003170
cell isolation
A single cell type that has been isolated by affinity purification or fluorescent cell sorting.
FBC:GD
A sample that has undergone fractionation in order to isolate specific subcellular components for study.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003171
subcellular fractionation
A sample that has undergone fractionation in order to isolate specific subcellular components for study.
FBC:CT
A sample in which specific cells within a tissue have been ablated by some method, such as targeted expression of a cell toxin, or laser ablation of fluorescently marked cells.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003172
cell ablation
A sample in which specific cells within a tissue have been ablated by some method, such as targeted expression of a cell toxin, or laser ablation of fluorescently marked cells.
FBC:GD
A sample that has been labelled in a targeted, cell-specific manner.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003173
targeted cell labeling
A sample that has been labelled in a targeted, cell-specific manner.
FBC:CT
Neuronal activity that has been perturbed using genetically controlled agents to activate or depress membrane potential.
mmc46
2016-02-24T19:19:21Z
biosample_attribute
FBcv:0003174
neuronal activity perturbation
Neuronal activity that has been perturbed using genetically controlled agents to activate or depress membrane potential.
FBC:GD
Some characteristic of an assay pertaining to the methods involved in processing the biological source material or generating the raw output data of the assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003175
assay attribute
Some characteristic of an assay pertaining to the methods involved in processing the biological source material or generating the raw output data of the assay.
FBC:GD
A type of biomolecule that is isolated from a biosample and characterized by downstream steps in an assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003176
assay material
A type of biomolecule that is isolated from a biosample and characterized by downstream steps in an assay.
FBC:GD
Material that is derived from isolation of genomic DNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003177
genomic DNA isolation
Material that is derived from isolation of genomic DNA.
FBC:CT
Material that is derived from isolation of the total RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003178
total RNA isolation
Material that is derived from isolation of the total RNA.
FBC:CT
Material that is derived from the isolation of RNA containing a poly(A) tail.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003179
poly(A) RNA isolation
Material that is derived from the isolation of RNA containing a poly(A) tail.
FBC:CT
The isolation of small RNA species 17-35 nt in size.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003180
short RNA isolation
The isolation of small RNA species 17-35 nt in size.
FBC:GD
Material that is derived from the isolation of translated messenger RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003181
translated mRNA isolation
Material that is derived from the isolation of translated messenger RNA.
FBC:CT
Material that is derived from the isolation of proteins.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003182
protein isolation
Material that is derived from the isolation of proteins.
FBC:CT
Material that is derived from the isolation of chromatin and its subcellular components and/or binding partners.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003183
chromatin isolation
Material that is derived from the isolation of chromatin and its subcellular components and/or binding partners.
FBC:CT
Isolation of RNA-protein complexes.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003184
RNA-protein isolation
Isolation of RNA-protein complexes.
FBC:GD
Material that is derived from the isolation of metabolites.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003185
metabolite isolation
Material that is derived from the isolation of metabolites.
FBC:CT
The biosample that is depleted of specific biomolecule types before further processing.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003186
assay material depletion
The biosample that is depleted of specific biomolecule types before further processing.
FBC:GD
Material that has undergone the depletion of ribosomal RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003187
rRNA depletion
Material that has undergone the depletion of ribosomal RNA.
FBC:CT
Material that has undergone the depletion of single-stranded RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003188
ssRNA depletion
Material that has undergone the depletion of single-stranded RNA.
FBC:CT
Material that has undergone the depletion of double-stranded RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003189
dsRNA depletion
Material that has undergone the depletion of double-stranded RNA.
FBC:CT
Material that has undergone the depletion of unbound RNA.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003190
unbound RNA depletion
Material that has undergone the depletion of unbound RNA.
FBC:CT
The biosample that is enriched for a specific biomolecule type for further processing.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003191
assay material selection
The biosample that is enriched for a specific biomolecule type for further processing.
FBC:GD
Material that has been selected using Chromatin Immunoprecipitation, or ChIP.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003192
ChIP
Material that has been selected using Chromatin Immunoprecipitation, or ChIP.
FBC:CT
Material that has been selected using DNA Adenine Methyltransferase Identification, or DamID.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003193
DamID
Material that has been selected using DNA Adenine Methyltransferase Identification, or DamID.
FBC:CT
Material that has been selected using formaldehyde-assisted isolation of Regulatory Elements or FAIRE.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003194
FAIRE
Material that has been selected using formaldehyde-assisted isolation of Regulatory Elements or FAIRE.
FBC:CT
Material that has been selected using Cap Analysis Gene Expression, in which the 7-methylguanosine cap at 5' transcript ends is biotinylated and affinity purified.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003195
CAGE
Material that has been selected using Cap Analysis Gene Expression, in which the 7-methylguanosine cap at 5' transcript ends is biotinylated and affinity purified.
PMID:16489339
Chromatin that has been cleaved using micrococcal nuclease to cleave at linker DNA between nucleosomes.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003196
MNase
Chromatin that has been cleaved using micrococcal nuclease to cleave at linker DNA between nucleosomes.
FBC:GD
Material that has been selected from a sample treated by deoxyribonuclease.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003197
DNase
Material that has been selected from a sample treated by deoxyribonuclease.
FBC:CT
Material that has been selected using a low salt chromatin extraction, typically 80mM.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003198
low salt chromatin extraction
Material that has been selected using a low salt chromatin extraction, typically 80mM.
FBC:CT
Material that has been selected using a high salt chromatin extraction, typically 600mM.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003199
high salt chromatin extraction
Material that has been selected using a high salt chromatin extraction, typically 600mM.
FBC:CT
Mononucleosomal fragments, generated by micrococcal nuclease cleavage at linker DNA between nucleosomes, that have been isolated by gel electrophoresis.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003200
mononucleosomal DNA isolation
Mononucleosomal fragments, generated by micrococcal nuclease cleavage at linker DNA between nucleosomes, that have been isolated by gel electrophoresis.
FBC:GD
Material that has been selected using affinity purification.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003201
affinity purification
Material that has been selected using affinity purification.
FBC:CT
Material that has been selected using size fractionation.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003202
size fractionation
Material that has been selected using size fractionation.
FBC:CT
Material that has been selected using short sequences of deoxy-thymine nucleotides to affinity purify RNA containing long polyA stretches.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003203
oligo-dT selection
Material that has been selected using short sequences of deoxy-thymine nucleotides to affinity purify RNA containing long polyA stretches.
FBC:CT
Material that has been selected using short sequences of deoxy-thymine nucleotides to prime first strand cDNA synthesis by reverse transcriptase at long polyA stretches.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003204
oligo-dT priming
Material that has been selected using short sequences of deoxy-thymine nucleotides to prime first strand cDNA synthesis by reverse transcriptase at long polyA stretches.
FBC:CT
Random oligomers that have been used to prime first strand cDNA synthesis by reverse transcriptase at random positions along transcripts.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003205
random priming
Random oligomers that have been used to prime first strand cDNA synthesis by reverse transcriptase at random positions along transcripts.
FBC:GD
Material that has been selected based on density via density sedimentation.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003206
density sedimentation
Material that has been selected based on density via density sedimentation.
FBC:CT
Nucleotide analogs that are used to map the position and orientation of the RNA polymerase active site.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003207
nuclear run-on
Nucleotide analogs that are used to map the position and orientation of the RNA polymerase active site.
FBC:GD
A method used to characterize the biological molecules isolated from a biosample.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003208
assay method
A method used to characterize the biological molecules isolated from a biosample.
FBC:GD
A method that uses Sanger sequencing for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003209
Sanger sequencing
A method that uses Sanger sequencing for this assay.
FBC:CT
A method that uses single molecule sequencing, by highly processive DNA polymerase to generate an extremely long single read on the order of several kilobases, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003210
single molecule real time sequencing
A method that uses single molecule sequencing, by highly processive DNA polymerase to generate an extremely long single read on the order of several kilobases, for this assay.
FBC:GD
A method that uses high-throughput sequencing for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003211
high-throughput sequencing
A method that uses high-throughput sequencing for this assay.
FBC:CT
A method that uses 454 sequencing, a form of high-throughput sequencing with 400-500 nt read length, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003212
454 sequencing
A method that uses 454 sequencing, a form of high-throughput sequencing with 400-500 nt read length, for this assay.
FBC:CT
A method that uses Illumina sequencing, a form of high-throughput sequencing, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003213
Illumina sequencing
A method that uses Illumina sequencing, a form of high-throughput sequencing, for this assay.
FBC:CT
A method that uses an Affymetrix Gene Expression Array, version 1, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003214
Affymetrix Gene Expression Array 1
A method that uses an Affymetrix Gene Expression Array, version 1, for this assay.
FBC:CT
FBC:GD
A method that uses an Affymetrix Gene Expression Array, version 2, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003215
Affymetrix Gene Expression Array 2
A method that uses an Affymetrix Gene Expression Array, version 2, for this assay.
FBC:CT
A method that uses a genomic tiling array, a subtype of microarray chip in which the genome is represented by oligonucleotides at regularly spaced intervals, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003216
genomic tiling array
A method that uses a genomic tiling array, a subtype of microarray chip in which the genome is represented by oligonucleotides at regularly spaced intervals, for this assay.
FBC:CT
A method that uses a peptide array, a subtype of microarray chip, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003217
peptide array
A method that uses a peptide array, a subtype of microarray chip, for this assay.
FBC:CT
A method that uses mass spectrometry, an analytical technique for sorting ions based on mass, for this assay.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003218
mass spectrometry
A method that uses mass spectrometry, an analytical technique for sorting ions based on mass, for this assay.
FBC:CT
A method that uses two samples, one a control and the other an experimental sample, for this assay. The samples are labeled in different colors and hybridized to the same oligonucleotide array. Each sample is scanned using different excitation and emission parameters.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003219
two channel scanning
A method that uses two samples, one a control and the other an experimental sample, for this assay. The samples are labeled in different colors and hybridized to the same oligonucleotide array. Each sample is scanned using different excitation and emission parameters.
FBC:GD
A method that uses an RNA-seq assay in which only one end of the library fragment is sequenced.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003220
single-end layout
A method that uses an RNA-seq assay in which only one end of the library fragment is sequenced.
FBC:GD
A method that uses an RNA-seq assay in which both ends of the library fragment are sequenced to provide additional mapping constraints.
mmc46
2016-02-24T19:19:21Z
assay_attribute
FBcv:0003221
paired-end layout
A method that uses an RNA-seq assay in which both ends of the library fragment are sequenced to provide additional mapping constraints.
FBC:GD
Some characteristic of a result pertaining to the methods involved in analyzing the input data, or the content or format of the output data.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003222
result attribute
Some characteristic of a result pertaining to the methods involved in analyzing the input data, or the content or format of the output data.
FBC:GD
A genomic mapping profile that distinguishes forward and reverse strand distributions.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003223
stranded profile
A genomic mapping profile that distinguishes forward and reverse strand distributions.
FBC:GD
A genomic mapping profile that does not distinguish between forward and reverse strand mapping.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003224
unstranded profile
A genomic mapping profile that does not distinguish between forward and reverse strand mapping.
FBC:GD
An alignment of high-throughput sequences that includes only those reads mapping uniquely to the genome.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003225
uniquely mapping read alignment
An alignment of high-throughput sequences that includes only those reads mapping uniquely to the genome.
FBC:GD
An alignment of high-throughput sequences that includes reads mapping to multiple sites in the genome. Coverage values for a given sequence weighted equally across the multiple sites to which it maps.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003226
multiply mapping read alignment
An alignment of high-throughput sequences that includes reads mapping to multiple sites in the genome. Coverage values for a given sequence weighted equally across the multiple sites to which it maps.
FBC:GD
A unit of expression (reads per kilobase per million reads) in which high-throughput sequencing reads mapping to a given feature are normalized both to the size of that feature and to the total number of reads in the sample.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003227
RPKM calculation
A unit of expression (reads per kilobase per million reads) in which high-throughput sequencing reads mapping to a given feature are normalized both to the size of that feature and to the total number of reads in the sample.
FBC:GD
A unit of expression (reads per million miRNA reads) in which high-throughput sequencing reads for a given miRNA are normalized against all reads mapping to all miRNA.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003228
RPMM calculation
A unit of expression (reads per million miRNA reads) in which high-throughput sequencing reads for a given miRNA are normalized against all reads mapping to all miRNA.
FBC:GD
A unit of expression (reads per million reads) in which high-throughput sequencing reads for a given type of feature are normalized against all reads mapping to all features of the same type.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003229
RPM calculation
A unit of expression (reads per million reads) in which high-throughput sequencing reads for a given type of feature are normalized against all reads mapping to all features of the same type.
FBC:GD
Sequencing the full extent of selected large clones, typically by sub-cloning large inserts as smaller fragments, to improve the accuracy and completeness of an assembly.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003230
clone-based finishing
Sequencing the full extent of selected large clones, typically by sub-cloning large inserts as smaller fragments, to improve the accuracy and completeness of an assembly.
FlyBase:FBrf0155823
Mapping of restriction enzyme recognition sites to develop a physical map of a genome.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003231
restriction fingerprinting
Mapping of restriction enzyme recognition sites to develop a physical map of a genome.
FBC:GD
Mapping of short (200-500 bp) sequence-tagged sites (STS) landmarks to develop a physical map of a genome.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003232
sequence tagged site mapping
Mapping of short (200-500 bp) sequence-tagged sites (STS) landmarks to develop a physical map of a genome.
FBC:GD
An ordered list of a minimal set of overlapping clones that provides complete coverage across an assembly.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003233
tiling path
An ordered list of a minimal set of overlapping clones that provides complete coverage across an assembly.
FBC:GD
Sequences that have been mapped to mitotic or polytene chromosomes to guide genome assembly.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003234
cytogenetic mapping
Sequences that have been mapped to mitotic or polytene chromosomes to guide genome assembly.
FBC:GD
There is sequence for one or more chromosomes. This could be a completely sequenced chromosome without gaps or a chromosome containing scaffolds or contigs with gaps between them. There may also be unplaced or unlocalized scaffolds.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003235
assembly level - chromosome
There is sequence for one or more chromosomes. This could be a completely sequenced chromosome without gaps or a chromosome containing scaffolds or contigs with gaps between them. There may also be unplaced or unlocalized scaffolds.
http://www.ncbi.nlm.nih.gov/assembly/help/
Some sequence contigs have been connected across gaps to create scaffolds, but no scaffolds have been placed on chromosomes.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003236
assembly level - scaffold
Some sequence contigs have been connected across gaps to create scaffolds, but no scaffolds have been placed on chromosomes.
http://www.ncbi.nlm.nih.gov/assembly/help/
The assembly represents the whole genome, though there may still be gaps.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003237
genome representation - full
The assembly represents the whole genome, though there may still be gaps.
http://www.ncbi.nlm.nih.gov/assembly/help/
The assembly represents only part of the organism's genome, because only a single chromosome was targeted, coverage is <1, or total length is less than half the average for other assemblies of the same species.
mmc46
2016-02-24T19:19:21Z
result_attribute
FBcv:0003238
genome representation - partial
The assembly represents only part of the organism's genome, because only a single chromosome was targeted, coverage is <1, or total length is less than half the average for other assemblies of the same species.
http://www.ncbi.nlm.nih.gov/assembly/help/
Sequence change caused by the cleavage of specific DNA sequences by zinc finger nucleases (ZFNs). ZFN proteins comprise a DNA binding domain linked to the DNA cleavage domain of FokI endonuclease. The DNA binding domain is composed of three Cys2His2 zinc fingers, with each zinc finger contacting three consecutive base pairs of DNA. The specificity of the binding is determined by the sequence of the three-zinc finger DNA binding domain, which recognizes a 9 base pair sequence. Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of ZFNs which bind to sequences in close proximity, allowing dimerization and promoting cleavage.
mmc46
2016-04-06T10:22:52Z
change induced by zinc finger nuclease-mediated cleavage
origin_of_mutation
zinc finger nuclease
FBcv:0003239
ZFN
Sequence change caused by the cleavage of specific DNA sequences by zinc finger nucleases (ZFNs). ZFN proteins comprise a DNA binding domain linked to the DNA cleavage domain of FokI endonuclease. The DNA binding domain is composed of three Cys2His2 zinc fingers, with each zinc finger contacting three consecutive base pairs of DNA. The specificity of the binding is determined by the sequence of the three-zinc finger DNA binding domain, which recognizes a 9 base pair sequence. Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of ZFNs which bind to sequences in close proximity, allowing dimerization and promoting cleavage.
PMID:10954606
PMID:12730594
PMID:8577732
mmc46
2016-05-17T15:35:41Z
assay_attribute
FBcv:0003240
expression array
Phenotype that is a defect in sensory perception of light stimulus (GO:0050953). 'sensory perception of light stimulus' is defined as: 'The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'
phenotypic_class
FBcv:0004000
visual perception defective
Phenotype that is a defect in sensory perception of light stimulus (GO:0050953). 'sensory perception of light stimulus' is defined as: 'The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'
FBC:MMC
GOC:ai
Sequence change caused by a site specific recombination catalyzed by the serine recombinase Bxb1 integrase that recognizes a minimal high-efficiency attPX recognition site of 48 base pairs and a minimal high-efficiency attBX recognition site of 38 base pairs. The attPX and attBX sites share an 8bp common core flanked by imperfect inverted repeats (19bp in attPX and 8bp in attBX). A non-palindromic central dinucleotide (5'-GT) determines the directionality of integration.
temj2
2017-06-12T10:56:07Z
change induced by Bxb1 integrase recombination
origin_of_mutation
FBcv:0005000
Bxb1 integrase
Sequence change caused by a site specific recombination catalyzed by the serine recombinase Bxb1 integrase that recognizes a minimal high-efficiency attPX recognition site of 48 base pairs and a minimal high-efficiency attBX recognition site of 38 base pairs. The attPX and attBX sites share an 8bp common core flanked by imperfect inverted repeats (19bp in attPX and 8bp in attBX). A non-palindromic central dinucleotide (5'-GT) determines the directionality of integration.
PMID:14636570
Term that describes the use of an experimental tool.
temj2
2017-06-28T11:41:27Z
FlyBase miscellaneous CV
FBcv:0005001
experimental tool descriptor
Term that describes the use of an experimental tool.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that gene product by an experimental method.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
gene product detection tag
FBcv:0005002
gene product detection tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that gene product by an experimental method.
FBC:GM
gene product detection tag
FBC:GM
Sequence that forms all or part of the RNA product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that RNA product by an experimental method.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
RNA detection tag
FBcv:0005003
RNA detection tool
Sequence that forms all or part of the RNA product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that RNA product by an experimental method.
FBC:GM
RNA detection tag
FBC:TJ
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that protein product by an experimental method.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
protein detection tag
FBcv:0005004
protein detection tool
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of that protein product by an experimental method.
FBC:GM
protein detection tag
FBC:TJ
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme whose activity can be used to detect the presence of that protein product.
temj2
2017-06-28T11:41:27Z
MI:0365
experimental_tool_descriptor
FBcv:0005005
reporter enzyme
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme whose activity can be used to detect the presence of that protein product.
FBC:GM
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that exhibits the property of fluorescence, that can be used to detect the presence of that protein product. A fluorescent protein emits light following the absorption of radiation, with the wavelength of the emitted light being longer than the excitation wavelength of the absorbed radiation.
temj2
2017-06-28T11:41:27Z
MI:0687
experimental_tool_descriptor
FBcv:0005006
fluorescent protein
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that exhibits the property of fluorescence, that can be used to detect the presence of that protein product. A fluorescent protein emits light following the absorption of radiation, with the wavelength of the emitted light being longer than the excitation wavelength of the absorbed radiation.
FBC:GM
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 499-519nm.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005007
green fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 499-519nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 424-467nm.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005008
blue fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 424-467nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 474-492nm.
temj2
2017-06-28T11:41:27Z
MI:0733
experimental_tool_descriptor
FBcv:0005009
cyan fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 474-492nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 524-538nm.
temj2
2017-06-28T11:41:27Z
MI:0368
experimental_tool_descriptor
FBcv:0005010
yellow fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 524-538nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 559-572nm.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005011
orange fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 559-572nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 574-610nm.
temj2
2017-06-28T11:41:27Z
MI:0732
experimental_tool_descriptor
FBcv:0005012
red fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 574-610nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 625-659nm.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005013
far-red fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak within the wavelength range of 625-659nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak equal or greater than 670nm.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005014
infra-red fluorescent protein
Protein having well characterized fluorescence excitation and emission spectra, with an emission peak equal or greater than 670nm.
FBC:GM
http://blog.addgene.org/which-fluorescent-protein-should-i-use
A fluorescent protein whose spectral properties are changeable, resulting from a reversible or irreversible change in fluorophore conformation. Changes in fluorophore conformation may occur either as a function of time (in the case of fluorescent timer proteins), or in response to an external trigger such as irradiation with a specific wavelength of light (in the case of photomodulatable fluorescent proteins).
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005015
modulatable fluorescent protein
A fluorescent protein whose spectral properties are changeable, resulting from a reversible or irreversible change in fluorophore conformation. Changes in fluorophore conformation may occur either as a function of time (in the case of fluorescent timer proteins), or in response to an external trigger such as irradiation with a specific wavelength of light (in the case of photomodulatable fluorescent proteins).
FBC:TEMJ
A fluorescent protein whose spectral properties can be modulated by exposure to light of a specific wavelength, triggering a conformational change of the fluorophore and subsequent change in fluorescent state.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005016
photomodulatable fluorescent protein
A fluorescent protein whose spectral properties can be modulated by exposure to light of a specific wavelength, triggering a conformational change of the fluorophore and subsequent change in fluorescent state.
FBC:TEMJ
PMID:20539741
A protein that can be switched from an essentially non-fluorescent state to a fluorescent state by irradiation with a pulse of light of a specific wavelength. This activation is irreversible.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005017
photoactivatable fluorescent protein
A protein that can be switched from an essentially non-fluorescent state to a fluorescent state by irradiation with a pulse of light of a specific wavelength. This activation is irreversible.
FBC:GM
http://www.leica-microsystems.com/science-lab/photoactivatable-photoconvertable-and-photoswitchable-fluorescent-proteins/
A protein that can be converted from one fluorescent state to another fluorescent state (with a changed emission spectrum peak) by irradiation with a pulse of light of a specific wavelength. This conversion is irreversible.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005018
photoconvertible fluorescent protein
A protein that can be converted from one fluorescent state to another fluorescent state (with a changed emission spectrum peak) by irradiation with a pulse of light of a specific wavelength. This conversion is irreversible.
FBC:GM
http://www.leica-microsystems.com/science-lab/photoactivatable-photoconvertable-and-photoswitchable-fluorescent-proteins/
A protein that can be reversibly switched between a non-fluorescent state and a fluorescent state, or between two different fluorescent states. The switch from one state to the other is triggered by irradiation with a pulse of light of a specific wavelength, and the switch back to the original state is triggered with a pulse of light of another specific wavelength.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005019
photoswitchable fluorescent protein
A protein that can be reversibly switched between a non-fluorescent state and a fluorescent state, or between two different fluorescent states. The switch from one state to the other is triggered by irradiation with a pulse of light of a specific wavelength, and the switch back to the original state is triggered with a pulse of light of another specific wavelength.
FBC:GM
FBC:TEMJ
http://www.leica-microsystems.com/science-lab/photoactivatable-photoconvertable-and-photoswitchable-fluorescent-proteins/
A protein that converts from one fluorescent state to another fluorescent state (with a changed emission spectrum peak) over time.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005020
fluorescent timer protein
A protein that converts from one fluorescent state to another fluorescent state (with a changed emission spectrum peak) over time.
FBC:GM
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an epitope that can be used to detect the presence of the tagged protein product. An epitope (SO:0001018) is defined as 'A binding site that, in the molecule, interacts selectively and non-covalently with antibodies, B cells or T cells.'
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005021
epitope tag
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes an epitope that can be used to detect the presence of the tagged protein product. An epitope (SO:0001018) is defined as 'A binding site that, in the molecule, interacts selectively and non-covalently with antibodies, B cells or T cells.'
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged gene product either to a specific subcellular location within the cell or for secretion to the extracellular space.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005022
gene product localization tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged gene product either to a specific subcellular location within the cell or for secretion to the extracellular space.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein either to a specific subcellular location within the cell or for secretion to the extracellular space.
temj2
2017-06-28T11:41:27Z
SO:0001527
experimental_tool_descriptor
FBcv:0005023
protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein either to a specific subcellular location within the cell or for secretion to the extracellular space.
FBC:GM
http://en.wikipedia.org/wiki/Target_peptide
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the nucleus.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005024
nuclear protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the nucleus.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the mitochondrion.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005025
mitochondrial protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the mitochondrion.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the peroxisome.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005026
peroxisomal protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the peroxisome.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the centrosome.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005027
centrosome protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the centrosome.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the microtubule.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005028
microtubule protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the microtubule.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the endoplasmic reticulum.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005029
endoplasmic reticulum protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the endoplasmic reticulum.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the Golgi apparatus.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005030
Golgi protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the Golgi apparatus.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to a cellular membrane. The membrane targeting sequence may be an intrinsic component of the membrane (GO:0031224), having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane; or may be an extrinsic component of the membrane (GO:0019898), being loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005031
membrane protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to a cellular membrane. The membrane targeting sequence may be an intrinsic component of the membrane (GO:0031224), having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane; or may be an extrinsic component of the membrane (GO:0019898), being loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
FBC:GM
GOC:dos
GOC:jl
GOC:mah
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the plasma membrane.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005032
plasma membrane protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the plasma membrane.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to a vesicle.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005033
vesicle protein localization tag
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to a vesicle.
FBC:GM
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the secretory pathway. This results in the protein either being secreted or inserted into a cellular membrane, depending on the presence of other specific sequences in the tagged protein. The signal sequence must be fused to the N-terminal end of the tagged protein.
temj2
2017-06-28T11:41:27Z
SO:0000418
experimental_tool_descriptor
FBcv:0005034
signal sequence
A peptide sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which is used to target the tagged protein to the secretory pathway. This results in the protein either being secreted or inserted into a cellular membrane, depending on the presence of other specific sequences in the tagged protein. The signal sequence must be fused to the N-terminal end of the tagged protein.
FBC:GM
http://en.wikipedia.org/wiki/Signal_peptide
A peptide sequence used to target a tagged protein for export from the nucleus to the cytoplasm.
temj2
2017-06-28T11:41:27Z
SO:0001531
NES
experimental_tool_descriptor
FBcv:0005035
nuclear export signal
A peptide sequence used to target a tagged protein for export from the nucleus to the cytoplasm.
FBC:GM
SO:0001531
http://en.wikipedia.org/wiki/Nuclear_export_signal
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific, novel property that facilitates purification of the gene product and/or any associated macromolecular complex by an experimental method.
temj2
2017-06-28T11:41:27Z
isolation tag
experimental_tool_descriptor
FBcv:0005036
purification tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific, novel property that facilitates purification of the gene product and/or any associated macromolecular complex by an experimental method.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which is used to regulate the activity of the tagged gene product.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005037
gene product activity regulation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which is used to regulate the activity of the tagged gene product.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the activity of the tagged gene product being regulated in response to a particular stimulus.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005038
conditional activity regulation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the activity of the tagged gene product being regulated in response to a particular stimulus.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the activity of the tagged gene product being regulated in response to irradiation with a pulse of light.
temj2
2017-06-28T11:41:27Z
light-dependent activity regulation tag
experimental_tool_descriptor
FBcv:0005039
light-regulated activity regulation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the activity of the tagged gene product being regulated in response to irradiation with a pulse of light.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being regulated by binding to a small molecule, such as an ion or ligand.
temj2
2017-06-28T11:41:27Z
small molecule-dependent activity regulation tag
experimental_tool_descriptor
FBcv:0005040
small molecule-regulated activity regulation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
Sequence that forms part of the protein encoded by a transgenic locus or modified endogenous locus and which allows a protein to be inactivated by the chromophore-assisted light inactivation (CALI) technique. The tag consists of a peptide sequence that specifically binds a membrane-permeable, chromophore-containing molecule. When activated using a pulse of high-intensity light that is absorbed by the chromophore but not by cellular components, the membrane-permeable molecule generates short-lived reactive oxygen species which inactivate the tagged protein to which the molecule is bound via the chromophore-assisted light inactivation tag.
temj2
2017-06-28T11:41:27Z
CALI tag
experimental_tool_descriptor
FBcv:0005041
chromophore-assisted light inactivation tag
Sequence that forms part of the protein encoded by a transgenic locus or modified endogenous locus and which allows a protein to be inactivated by the chromophore-assisted light inactivation (CALI) technique. The tag consists of a peptide sequence that specifically binds a membrane-permeable, chromophore-containing molecule. When activated using a pulse of high-intensity light that is absorbed by the chromophore but not by cellular components, the membrane-permeable molecule generates short-lived reactive oxygen species which inactivate the tagged protein to which the molecule is bound via the chromophore-assisted light inactivation tag.
FBC:GM
PMID:14625562
PMID:16605242
PMID:21226520
PMID:3399501
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005042
gene product degradation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process that is dependent on the cell cycle.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005043
cell-cycle regulated gene product degradation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process that is dependent on the cell cycle.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of a biologically relevant property that is not part of or directly encoded by the genome, for example pH, redox state, membrane potential, a change in concentration of a particular molecule. For experimental tools that are used to detect a gene product directly encoded by the genome, see instead 'gene product detection tag'.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005044
genetically encoded sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of a biologically relevant property that is not part of or directly encoded by the genome, for example pH, redox state, membrane potential, a change in concentration of a particular molecule. For experimental tools that are used to detect a gene product directly encoded by the genome, see instead 'gene product detection tag'.
FBC:GM
PMID:20664080
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of a molecule that is not part of or directly encoded by the genome.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005045
small molecule sensor
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and confers a specific property that facilitates detection of a molecule that is not part of or directly encoded by the genome.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of calcium ion concentration.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005046
calcium ion sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of calcium ion concentration.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of pH.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005047
pH sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of pH.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of voltage.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005048
voltage sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of voltage.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the redox state of a cell/tissue.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005049
redox state sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the redox state of a cell/tissue.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of changes in the mechanical force the gene product is subjected to.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005050
mechanical force sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of changes in the mechanical force the gene product is subjected to.
FBC:GM
Component that forms part of a 'split system'. A split system component corresponds to a non-functional fragment of a functional experimental tool that would normally be encoded by a single gene product. When combined with another appropriate split system component in vivo, a functional experimental tool is produced. The fragments of a split system can be brought together in vivo in a number of different ways; for example, by fusing fragments to peptides that physically interact in vivo.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005051
split system component
Component that forms part of a 'split system'. A split system component corresponds to a non-functional fragment of a functional experimental tool that would normally be encoded by a single gene product. When combined with another appropriate split system component in vivo, a functional experimental tool is produced. The fragments of a split system can be brought together in vivo in a number of different ways; for example, by fusing fragments to peptides that physically interact in vivo.
FBC:GM
Non-fluorescent fragment of a fluorescent protein. A functional fluorophore can be reconstituted if a split fluorescent protein fragment is expressed with a complementary split fluorescent protein fragment and the fragments are brought together in vivo, permitting the study of biological interactions. Protein-protein interactions can be studied using the bimolecular fluorescence complementation (BiFC) technique, where a fluorescent protein is reconstituted if the two complementary split fluorescent protein fragments are fused to interacting proteins or protein domains that bring the split halves together into the same macromolecular complex. Associations between closely apposed cells can be studied if the two complementary split fluorescent protein fragments are tethered to the surface of these cells, for example to study connectivity in the nervous system using the GFP Reconstitution Across Synaptic Partners (GRASP) technique.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005052
split fluorescent protein
Non-fluorescent fragment of a fluorescent protein. A functional fluorophore can be reconstituted if a split fluorescent protein fragment is expressed with a complementary split fluorescent protein fragment and the fragments are brought together in vivo, permitting the study of biological interactions. Protein-protein interactions can be studied using the bimolecular fluorescence complementation (BiFC) technique, where a fluorescent protein is reconstituted if the two complementary split fluorescent protein fragments are fused to interacting proteins or protein domains that bring the split halves together into the same macromolecular complex. Associations between closely apposed cells can be studied if the two complementary split fluorescent protein fragments are tethered to the surface of these cells, for example to study connectivity in the nervous system using the GFP Reconstitution Across Synaptic Partners (GRASP) technique.
FBC:GM
PMID:11983170
PMID:18255029
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes a catalytically inactive fragment of an enzyme whose activity can be used to detect the presence of that protein product when complementary split reporter enzyme fragments are brought together in vivo. Fragments may be brought together when fused to peptides that physically interact, permitting the study of protein-protein interactions.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005053
split reporter enzyme
Sequence that forms all or part of the protein product encoded by a transgenic locus or modified endogenous locus and that encodes a catalytically inactive fragment of an enzyme whose activity can be used to detect the presence of that protein product when complementary split reporter enzyme fragments are brought together in vivo. Fragments may be brought together when fused to peptides that physically interact, permitting the study of protein-protein interactions.
FBC:GM
PMID:9237989
http://orcid.org/0000-0002-1373-1705
Sequence encoding a site-specific DNA-binding domain fused to a heterodimerization domain, e.g. a leucine zipper. A functional transcriptional driver can be reconstituted if this split system component is brought together in vivo with a split system component that encodes a transcription activation domain fused to the complementary heterodimerization domain.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005054
split driver - DNA-binding fragment
Sequence encoding a site-specific DNA-binding domain fused to a heterodimerization domain, e.g. a leucine zipper. A functional transcriptional driver can be reconstituted if this split system component is brought together in vivo with a split system component that encodes a transcription activation domain fused to the complementary heterodimerization domain.
FBC:GM
FlyBase:FBrf0193617
Sequence encoding a transcription activation domain fused to a heterodimerization domain. A functional transcription driver can be reconstituted if this split system component is brought together in vivo with a split system component that encodes a DNA-binding domain fused to the complementary heterodimerization domain.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005055
split driver - transcription activation fragment
Sequence encoding a transcription activation domain fused to a heterodimerization domain. A functional transcription driver can be reconstituted if this split system component is brought together in vivo with a split system component that encodes a DNA-binding domain fused to the complementary heterodimerization domain.
FBC:GM
FlyBase:FBrf0193617
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which allows the tagged gene product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005056
gene product cleavage tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which allows the tagged gene product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process.
FBC:GM
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which allows the tagged protein product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process. Examples of protein cleavage tags include sequences recognized and cleaved by proteases such as the human rhinovirus (HRV) 3C protease (often produced with the tradename PreScission Protease) and the tobacco etch virus (TEV) protease. Protein product cleavage can be used for a number of different purposes, including release of a protein after purification, or removal of a detection tag to assess that the tag does not interfere with protein function.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005057
protein cleavage tag
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which allows the tagged protein product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process. Examples of protein cleavage tags include sequences recognized and cleaved by proteases such as the human rhinovirus (HRV) 3C protease (often produced with the tradename PreScission Protease) and the tobacco etch virus (TEV) protease. Protein product cleavage can be used for a number of different purposes, including release of a protein after purification, or removal of a detection tag to assess that the tag does not interfere with protein function.
FBC:GM
FBC:TEMJ
Component that forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005058
binary expression system component
Component that forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
FBC:GM
FlyBase:FBrf0216478
Transactivator ('driver') that is encoded by a transgenic locus or modified endogenous locus and which forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005059
binary expression system - driver
Transactivator ('driver') that is encoded by a transgenic locus or modified endogenous locus and which forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
FBC:GM
FlyBase:FBrf0216478
Specific DNA sequence that is used as the effector in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
temj2
2017-06-28T11:41:27Z
binary expression system - effector
experimental_tool_descriptor
FBcv:0005060
binary expression system - regulatory region
Specific DNA sequence that is used as the effector in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
FBC:GM
FlyBase:FBrf0216478
Repressor that can be used to regulate expression in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
temj2
2017-06-28T11:41:27Z
experimental_tool_descriptor
FBcv:0005061
binary expression system - repressor
Repressor that can be used to regulate expression in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.
FBC:GM
FlyBase:FBrf0216478
An enzyme that mediates a recombination exchange reaction between two DNA templates, each containing a specific recognition site. The recognition site for a particular site-specific recombinase is defined by the enzyme itself. The recognition site contains perfect inverted repeats flanking an asymmetric spacer. Under normal conditions, the two recognition sites are identical and are reformed during the recombination event, and thus the reaction is bidirectional: recombination can occur in both 'forward' and 'reverse' directions. However, recognition sites can be mutated to drive the directionality of the reaction: different classes of site may be combined so that recombination can occur in one direction, but produces reformed sites that are no longer compatible. In addition, mutually exclusive sites have been engineered for some recombinases. Recombinases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
temj2
2017-06-28T11:41:27Z
site-specific recombinase
experimental_tool_descriptor
FBcv:0005062
recombinase
An enzyme that mediates a recombination exchange reaction between two DNA templates, each containing a specific recognition site. The recognition site for a particular site-specific recombinase is defined by the enzyme itself. The recognition site contains perfect inverted repeats flanking an asymmetric spacer. Under normal conditions, the two recognition sites are identical and are reformed during the recombination event, and thus the reaction is bidirectional: recombination can occur in both 'forward' and 'reverse' directions. However, recognition sites can be mutated to drive the directionality of the reaction: different classes of site may be combined so that recombination can occur in one direction, but produces reformed sites that are no longer compatible. In addition, mutually exclusive sites have been engineered for some recombinases. Recombinases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
FlyBase:FBrf0231034
The recognition site for a particular site-specific recombinase, an enzyme that mediates a recombination exchange reaction between two DNA templates, each containing a copy of the recognition site. The recognition site contains perfect inverted repeats flanking an asymmetric spacer. Under normal conditions, the two recognition sites are identical and are reformed during the recombination event, and thus the reaction is bidirectional: recombination can occur in both 'forward' and 'reverse' directions. However, recognition sites can be mutated to drive the directionality of the reaction: different classes of site may be combined so that recombination can occur in one direction, but produces reformed sites that are no longer compatible. In addition, mutually exclusive sites have been engineered for some recombinases. Recombinases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
temj2
2017-06-28T11:41:27Z
site-specific recombination target region
experimental_tool_descriptor
FBcv:0005063
recombinase target site
The recognition site for a particular site-specific recombinase, an enzyme that mediates a recombination exchange reaction between two DNA templates, each containing a copy of the recognition site. The recognition site contains perfect inverted repeats flanking an asymmetric spacer. Under normal conditions, the two recognition sites are identical and are reformed during the recombination event, and thus the reaction is bidirectional: recombination can occur in both 'forward' and 'reverse' directions. However, recognition sites can be mutated to drive the directionality of the reaction: different classes of site may be combined so that recombination can occur in one direction, but produces reformed sites that are no longer compatible. In addition, mutually exclusive sites have been engineered for some recombinases. Recombinases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
FlyBase:FBrf0231034
Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated in response to a particular stimulus. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a conditional driver permits further refinement of this expression pattern.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005064
binary expression system - conditional driver
Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated in response to a particular stimulus. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a conditional driver permits further refinement of this expression pattern.
FBC:GM
Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated by binding to a small molecule, such as an ion or ligand. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a small molecule-regulated driver driver permits further refinement of this expression pattern.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005065
binary expression system - small molecule-regulated driver
Transactivator ('driver') that forms part of a binary expression system and whose activity is regulated by binding to a small molecule, such as an ion or ligand. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. Use of a small molecule-regulated driver driver permits further refinement of this expression pattern.
FBC:GM
Repressor that can be used to regulate expression in a binary expression system and whose activity is regulated in response to a particular stimulus. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder. Use of a conditional repressor permits further refinement of this expression pattern.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005066
binary expression system - conditional repressor
Repressor that can be used to regulate expression in a binary expression system and whose activity is regulated in response to a particular stimulus. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder. Use of a conditional repressor permits further refinement of this expression pattern.
FBC:GM
Repressor that can be used to regulate expression in a binary expression system and whose activity is regulated by temperature. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder. Use of a temperature conditional repressor permits further refinement of this expression pattern.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005067
binary expression system - temperature conditional repressor
Repressor that can be used to regulate expression in a binary expression system and whose activity is regulated by temperature. A binary expression system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder. Use of a temperature conditional repressor permits further refinement of this expression pattern.
FBC:GM
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which is designed to impact or assess any proximate gene(s) when integrated into the genome.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005068
insertional mutagenesis tool
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which is designed to impact or assess any proximate gene(s) when integrated into the genome.
FBC:GM
FBC:LC
An enhancer trap cassette is designed to report or utilize the expression of endogenous enhancer elements upon integration of the cassette into the genome. The basic components of an enhancer trap cassette are a minimal promoter element fused upstream of a gene. Upon integration into the genome, a neighboring genomic enhancer may activate expression of the gene encoded by the enhancer trap cassette. Depending on the nature of this gene, the insertion may directly report the expression pattern of the 'trapped' enhancer (e.g. if the gene encodes a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest (e.g. if the gene encodes a driver that forms part of a binary expression system). An enhancer trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. An enhancer trap insertion can be mutagenic, disrupting the function of an endogenous locus, depending on the particular insertion site.
temj2
2017-12-13T13:17:30Z
SO:0001479
experimental_tool_descriptor
enhancer detection tool
FBcv:0005069
enhancer trap
An enhancer trap cassette is designed to report or utilize the expression of endogenous enhancer elements upon integration of the cassette into the genome. The basic components of an enhancer trap cassette are a minimal promoter element fused upstream of a gene. Upon integration into the genome, a neighboring genomic enhancer may activate expression of the gene encoded by the enhancer trap cassette. Depending on the nature of this gene, the insertion may directly report the expression pattern of the 'trapped' enhancer (e.g. if the gene encodes a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest (e.g. if the gene encodes a driver that forms part of a binary expression system). An enhancer trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. An enhancer trap insertion can be mutagenic, disrupting the function of an endogenous locus, depending on the particular insertion site.
FBC:GM
FlyBase:FBrf0128252
FlyBase:FBrf0216478
PMID:10899970
enhancer detection tool
FBC:GM
A protein trap cassette is designed to tag protein(s) encoded by an endogenous locus upon integration of the cassette into the genome. The basic structure of a protein trap cassette is an artificial exon composed of a splice acceptor site, an open reading frame without initiation and stop codons, and a splice donor site. No promoter sequences are present. Upon integration into a coding intron of an endogenous locus, the open reading frame (ORF) encoded by the artificial exon can be incorporated into ('tag') the protein encoded by the locus. This only occurs if the insertion is in the correct orientation and when the frame of the artificial exon corresponds to that of the preceeding exon. Thus, only one out of six insertions in a coding intron will function as a protein trap. To account for each reading frame, three versions of a given protein trap element, differing only in the splice phase, are typically produced for use in an insertional mutagenesis screen. Depending on the nature of the ORF encoded by the artificial exon, the tag may be used to detect the expression pattern and/or subcellular localization of the protein (e.g. if the tag is an epitope tag or fluorescent protein), to drive expression of a gene of interest (e.g. if the tag is a driver that forms part of a binary expression system), or may modify the properties of the endogenous protein (e.g. if the tag affects protein localization or stability). A protein trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. The presence of the splice acceptor and donor sites mean that a protein trap cassette is not inherently mutagenic, since it is designed to insert in frame into a protein. However, an insertion into an intron that splits a critical functional or localization domain may alter the activity of the encoded protein, and the protein trap tag sequence itself may be designed to alter function (for example targeting the protein to a new location within the cell or altering its stability).
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005070
protein trap
A protein trap cassette is designed to tag protein(s) encoded by an endogenous locus upon integration of the cassette into the genome. The basic structure of a protein trap cassette is an artificial exon composed of a splice acceptor site, an open reading frame without initiation and stop codons, and a splice donor site. No promoter sequences are present. Upon integration into a coding intron of an endogenous locus, the open reading frame (ORF) encoded by the artificial exon can be incorporated into ('tag') the protein encoded by the locus. This only occurs if the insertion is in the correct orientation and when the frame of the artificial exon corresponds to that of the preceeding exon. Thus, only one out of six insertions in a coding intron will function as a protein trap. To account for each reading frame, three versions of a given protein trap element, differing only in the splice phase, are typically produced for use in an insertional mutagenesis screen. Depending on the nature of the ORF encoded by the artificial exon, the tag may be used to detect the expression pattern and/or subcellular localization of the protein (e.g. if the tag is an epitope tag or fluorescent protein), to drive expression of a gene of interest (e.g. if the tag is a driver that forms part of a binary expression system), or may modify the properties of the endogenous protein (e.g. if the tag affects protein localization or stability). A protein trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. The presence of the splice acceptor and donor sites mean that a protein trap cassette is not inherently mutagenic, since it is designed to insert in frame into a protein. However, an insertion into an intron that splits a critical functional or localization domain may alter the activity of the encoded protein, and the protein trap tag sequence itself may be designed to alter function (for example targeting the protein to a new location within the cell or altering its stability).
FBC:GM
FlyBase:FBrf0216478
FlyBase:FBrf0236840
A gene trap cassette is designed to interrupt transcription of an endogenous locus upon integration of the cassette into the genome. The basic components of a gene trap cassette are a promoterless gene with an upstream splice acceptor site. Upon integration into an intron, splicing from the genomic splice donor site to the splice acceptor site in the cassette results in a transcriptional fusion containing the endogenous exon(s) upstream of the insertion fused to the gene sequence encoded by the cassette. Any open reading frame (ORF) encoded by the trap cassette gene may be translated from this transcriptional fusion either as a translational fusion with any ORF sequence encoded by the upstream exons, or if an internal ribosome entry site (IRES) or viral 2A-like peptide sequence (which promotes ribosome skipping) is present upstream of the gene trap ORF, it may be produced as a separate protein expressed under the control of the regulatory sequences of the endogenous locus. Gene trap insertions are usually mutagenic, disrupting the locus into which they have inserted, since termination sequences are usually present at the 3' end of the cassette, truncating the endogenous transcript. Depending on the nature of the gene encoded by the gene trap cassette, a gene trap insertion may directly report the expression pattern of the disrupted locus (e.g. if it encodes a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest in the pattern of the trapped locus (e.g. if it is a driver that forms part of a binary expression system). A gene trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR.
temj2
2017-12-13T13:17:30Z
SO:0001477
experimental_tool_descriptor
FBcv:0005071
gene trap
A gene trap cassette is designed to interrupt transcription of an endogenous locus upon integration of the cassette into the genome. The basic components of a gene trap cassette are a promoterless gene with an upstream splice acceptor site. Upon integration into an intron, splicing from the genomic splice donor site to the splice acceptor site in the cassette results in a transcriptional fusion containing the endogenous exon(s) upstream of the insertion fused to the gene sequence encoded by the cassette. Any open reading frame (ORF) encoded by the trap cassette gene may be translated from this transcriptional fusion either as a translational fusion with any ORF sequence encoded by the upstream exons, or if an internal ribosome entry site (IRES) or viral 2A-like peptide sequence (which promotes ribosome skipping) is present upstream of the gene trap ORF, it may be produced as a separate protein expressed under the control of the regulatory sequences of the endogenous locus. Gene trap insertions are usually mutagenic, disrupting the locus into which they have inserted, since termination sequences are usually present at the 3' end of the cassette, truncating the endogenous transcript. Depending on the nature of the gene encoded by the gene trap cassette, a gene trap insertion may directly report the expression pattern of the disrupted locus (e.g. if it encodes a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest in the pattern of the trapped locus (e.g. if it is a driver that forms part of a binary expression system). A gene trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR.
FBC:GM
PMID:10899970
http://www.genetrap.org/tutorials/overview.html#vector
The basic components of a polyA trap cassette are a promoter fused to a gene sequence that lacks a polyadenylation (polyA) sequence but is followed by a splice donor sequence. If the cassette is integrated into the genome outside a gene, the mRNA produced by the polyA trap is not polyadenylated and is expected to be rapidly degraded. However, if the cassette is integrated into an intron, the promoter in the polyA trap will drive expression of a transcriptional fusion containing the polyA gene trap fused to any downstream exons. The downstream terminal exon can provide a polyA signal, allowing stable expression of the gene encoded by the polyA trap. polyA trap cassettes can be used to report the expression of genes that are not normally expressed, or are expressed at very low levels, or may be used as a marker of successful integration of an insertion into a transcription unit. A polyA trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005072
polyA trap
The basic components of a polyA trap cassette are a promoter fused to a gene sequence that lacks a polyadenylation (polyA) sequence but is followed by a splice donor sequence. If the cassette is integrated into the genome outside a gene, the mRNA produced by the polyA trap is not polyadenylated and is expected to be rapidly degraded. However, if the cassette is integrated into an intron, the promoter in the polyA trap will drive expression of a transcriptional fusion containing the polyA gene trap fused to any downstream exons. The downstream terminal exon can provide a polyA signal, allowing stable expression of the gene encoded by the polyA trap. polyA trap cassettes can be used to report the expression of genes that are not normally expressed, or are expressed at very low levels, or may be used as a marker of successful integration of an insertion into a transcription unit. A polyA trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR.
FBC:GM
FlyBase:FBrf0132344
FlyBase:FBrf0206814
PMID:9560157
http://www.genetrap.org/tutorials/overview.html#vector
The basic component of a promoter trap cassette is a promoterless gene. This gene is not flanked by splice acceptor or donor sites, and thus the gene within a promoter trap can only be expressed if the cassette integrates into the genome within an exon, resulting in a transcriptional fusion. If the promoter trap gene encodes an open reading frame (ORF) and the insertion is in the correct frame, the trap ORF may be translated from this transcriptional fusion either as a translational fusion with ORF sequence of the disrupted endogenous locus, or if an internal ribosome entry site (IRES) or viral 2A-like peptide sequence (which promotes ribosome skipping) is present upstream of the promoter trap ORF, it may be produced as a separate protein expressed under the control of the regulatory sequences of the endogenous locus. Depending on the nature of the gene encoded by the promoter trap cassette, the insertion may directly report the expression pattern of the 'trapped' locus (e.g. if the gene encoded by the cassette is a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest (e.g. if the gene encoded by the cassette is a driver that form part of a binary expression system). A promoter trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. Promoter trap insertions are usually mutagenic, disrupting the locus into which they have inserted, since termination sequences are usually present at the 3' end of the cassette, truncating the endogenous transcript.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005073
promoter trap
The basic component of a promoter trap cassette is a promoterless gene. This gene is not flanked by splice acceptor or donor sites, and thus the gene within a promoter trap can only be expressed if the cassette integrates into the genome within an exon, resulting in a transcriptional fusion. If the promoter trap gene encodes an open reading frame (ORF) and the insertion is in the correct frame, the trap ORF may be translated from this transcriptional fusion either as a translational fusion with ORF sequence of the disrupted endogenous locus, or if an internal ribosome entry site (IRES) or viral 2A-like peptide sequence (which promotes ribosome skipping) is present upstream of the promoter trap ORF, it may be produced as a separate protein expressed under the control of the regulatory sequences of the endogenous locus. Depending on the nature of the gene encoded by the promoter trap cassette, the insertion may directly report the expression pattern of the 'trapped' locus (e.g. if the gene encoded by the cassette is a reporter enzyme or fluorescent protein), or it may be used to drive expression of any gene of interest (e.g. if the gene encoded by the cassette is a driver that form part of a binary expression system). A promoter trap cassette may be inserted into a genome as part of a transgenic construct via transposable-element-mediated transgenesis, or may be inserted directly into a modified endogenous locus via a genome engineering method such as homologous recombination or CRISPR. Promoter trap insertions are usually mutagenic, disrupting the locus into which they have inserted, since termination sequences are usually present at the 3' end of the cassette, truncating the endogenous transcript.
FBC:GM
PMID:10899970
The basic components of a misexpression element are an enhancer sequence plus a minimal promoter. Upon integration into the genome, this element can activate expression of nearby endogenous loci. Typically, constructs containing misexpression elements are designed to insert at or near the 5' end of a gene, such that expression from the promoter within the misexpression element drives overexpression of the endogenous locus and causes a gain-of-function phenotype. However, if the insertion is within a locus, a truncated product may be produced, while an insertion in the opposite orientation to that of the direction of transcription of the endogenous locus can result in the production of an antisense transcript. If the enhancer present in the misexpression element forms part of a binary expression system, the misexpression pattern of the endogenous gene is controlled by combining the misexpression element insertion with a driver expressed in the desired temporal and spatial pattern.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005074
misexpression element
The basic components of a misexpression element are an enhancer sequence plus a minimal promoter. Upon integration into the genome, this element can activate expression of nearby endogenous loci. Typically, constructs containing misexpression elements are designed to insert at or near the 5' end of a gene, such that expression from the promoter within the misexpression element drives overexpression of the endogenous locus and causes a gain-of-function phenotype. However, if the insertion is within a locus, a truncated product may be produced, while an insertion in the opposite orientation to that of the direction of transcription of the endogenous locus can result in the production of an antisense transcript. If the enhancer present in the misexpression element forms part of a binary expression system, the misexpression pattern of the endogenous gene is controlled by combining the misexpression element insertion with a driver expressed in the desired temporal and spatial pattern.
FBC:GM
FlyBase:FBrf0090768
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which can be used to an modify an organism's genetic material in a defined manner. Genome engineering can occur on many levels, ranging from targeting of an individual gene with a small modification through to the engineering of chromosomal rearrangements. In addition to the manipulation of endogenous loci, genome engineering can also be used to introduce exogenous material into the genome, and to manipulate such exogenous material already introduced the genome.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005075
genome engineering tool
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which can be used to an modify an organism's genetic material in a defined manner. Genome engineering can occur on many levels, ranging from targeting of an individual gene with a small modification through to the engineering of chromosomal rearrangements. In addition to the manipulation of endogenous loci, genome engineering can also be used to introduce exogenous material into the genome, and to manipulate such exogenous material already introduced the genome.
FlyBase:FBrf0231034
An enzyme that mediates an exchange reaction between two DNA templates, resulting in integration of DNA from one of the templates into the other. An integrase binds a pair of compatible recognition sites (typically called attP and attB) which each contain a short integration core flanked by imperfect inverted repeats that are not identical. Exchange between the attP/attB pair results in the formation of hybrid sites (typically called attL and attR) that are no longer a substrate of the integrase. Thus the exchange reaction driven by an integrase is unidirectional. Mutually exclusive pairs of recognition site have been engineered for some integrases. Integrases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005076
integrase
An enzyme that mediates an exchange reaction between two DNA templates, resulting in integration of DNA from one of the templates into the other. An integrase binds a pair of compatible recognition sites (typically called attP and attB) which each contain a short integration core flanked by imperfect inverted repeats that are not identical. Exchange between the attP/attB pair results in the formation of hybrid sites (typically called attL and attR) that are no longer a substrate of the integrase. Thus the exchange reaction driven by an integrase is unidirectional. Mutually exclusive pairs of recognition site have been engineered for some integrases. Integrases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
FlyBase:FBrf0231034
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
site-specific DNA nuclease
FBcv:0005077
nuclease
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
FBC:GM
FlyBase:FBrf0231034
site-specific DNA nuclease
FBC:GM
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner, and in which the specificity is determined by a guide RNA that contains sequence complementary to the DNA sequence of interest, rather than being an inherent property of the nuclease itself.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005078
RNA-guided nuclease
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner, and in which the specificity is determined by a guide RNA that contains sequence complementary to the DNA sequence of interest, rather than being an inherent property of the nuclease itself.
FBC:GM
FlyBase:FBrf0231034
A recognition site for an integrase, an enzyme that mediates an exchange reaction between two DNA templates, resulting in integration of DNA from one of the templates into the other. An integrase binds a pair of compatible recognition sites (typically called attP and attB) which each contain a short integration core flanked by imperfect inverted repeats that are not identical. Exchange between the attP/attB pair results in the formation of hybrid sites (typically called attL and attR) that are no longer a substrate of the integrase. Thus the exchange reaction driven by an integrase is unidirectional. Mutually exclusive pairs of recognition site have been engineered for some integrases. Integrases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005079
integrase target site
A recognition site for an integrase, an enzyme that mediates an exchange reaction between two DNA templates, resulting in integration of DNA from one of the templates into the other. An integrase binds a pair of compatible recognition sites (typically called attP and attB) which each contain a short integration core flanked by imperfect inverted repeats that are not identical. Exchange between the attP/attB pair results in the formation of hybrid sites (typically called attL and attR) that are no longer a substrate of the integrase. Thus the exchange reaction driven by an integrase is unidirectional. Mutually exclusive pairs of recognition site have been engineered for some integrases. Integrases can be used to generate many different types of genetic modification, with the outcome being influenced by the relative orientation (direct or inverted), relative location and composition of the two recognition sites. The types of possible modification include deletion of DNA, generation of chromosomal rearrangements, integration of DNA into the genome, and replacement of genetic material with that from a donor plasmid using recombination-mediated cassette exchange (RMCE).
FlyBase:FBrf0231034
A recognition site for a site-specific DNA nuclease, an enzyme that catalyzes hydrolysis of DNA in a site-specific manner. The DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005080
nuclease target site
A recognition site for a site-specific DNA nuclease, an enzyme that catalyzes hydrolysis of DNA in a site-specific manner. The DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
FBC:GM
FlyBase:FBrf0231034
Engineered sequence that forms all or part of a transgenic locus or modified endogenous locus and that has the property of a 'regulatory_region' (SO:0005836). 'regulatory_region' is defined as 'A region of sequence that is involved in the control of a biological process.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005081
engineered regulatory region
Engineered sequence that forms all or part of a transgenic locus or modified endogenous locus and that has the property of a 'regulatory_region' (SO:0005836). 'regulatory_region' is defined as 'A region of sequence that is involved in the control of a biological process.
FBC:GM
Engineered sequence that forms all or part of a transgenic locus or modified endogenous locus and that has the property of a 'transcription_regulatory_region' (SO:0001679). 'transcription_regulatory_region' is defined as 'A regulatory region that is involved in the control of the process of transcription.'.
temj2
2017-12-13T13:17:30Z
experimental_tool_descriptor
FBcv:0005082
engineered transcription regulatory region
Engineered sequence that forms all or part of a transgenic locus or modified endogenous locus and that has the property of a 'transcription_regulatory_region' (SO:0001679). 'transcription_regulatory_region' is defined as 'A regulatory region that is involved in the control of the process of transcription.'.
FBC:GM
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process that is regulated by a small molecule.
temj2
2017-12-22T13:09:10Z
small molecule-dependent gene product degradation tag
experimental_tool_descriptor
FBcv:0005083
small molecule-regulated gene product degradation tag
Sequence that forms part of the gene product encoded by a transgenic locus or modified endogenous locus and which results in the tagged gene product being targeted for degradation by a specific process that is regulated by a small molecule.
FBC:GM
Phenotype that is a defect in copulation (GO:0007620). 'copulation' is defined as: 'The act of sexual union between male and female, involving the transfer of sperm.'
phenotypic_class
FBcv:0006000
copulation defective
Phenotype that is a defect in copulation (GO:0007620). 'copulation' is defined as: 'The act of sexual union between male and female, involving the transfer of sperm.'
FBC:TEMJ
ISBN:0721662544
Phenotype that is an increase in the number of gametes produced.
phenotypic_class
FBcv:0006001
increased fecundity
Phenotype that is an increase in the number of gametes produced.
FBC:TEMJ
Phenotype that is a decrease in the number of gametes produced.
phenotypic_class
FBcv:0006002
decreased fecundity
Phenotype that is a decrease in the number of gametes produced.
FBC:TEMJ
population of Drosophila
Phenotype that is a defect in oviposition (GO:0007620). 'oviposition' is defined as: 'The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.'.
phenotypic_class
FBcv:0006004
This term should only be used to report defects specifically in oviposition, as opposed to an overall loss of fertility. If a difference in "oviposition rate" is measured by authors as a proxy for sterility/fertility, it would be better to use the terms "sterile", "semi-sterile", or "semi-fertile", as appropriate.
oviposition defective
Phenotype that is a defect in oviposition (GO:0007620). 'oviposition' is defined as: 'The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.'.
FBC:TEMJ
GOC:ems
A phenotype that is an increased occurrence of cell division (GO:0051301). 'cell division' is defined as 'The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.'.
phenotypic_class
FBcv:0006005
increased occurrence of cell division
A phenotype that is an increased occurrence of cell division (GO:0051301). 'cell division' is defined as 'The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.'.
FBC:TEMJ
GOC:di
GOC:go_curators
GOC:pr
A phenotype that is a decreased occurrence of cell division (GO:0051301). 'cell division' is defined as 'The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.'.
phenotypic_class
FBcv:0006006
decreased occurrence of cell division
A phenotype that is a decreased occurrence of cell division (GO:0051301). 'cell division' is defined as 'The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.'.
FBC:TEMJ
GOC:di
GOC:go_curators
GOC:pr
population of cells
A short report describing a single stand-alone research finding that is peer-reviewed and published.
http://orcid.org/0000-0002-1373-1705
2019-06-25T08:45:04Z
pub_type
FBcv:0007000
micropublication
A short report describing a single stand-alone research finding that is peer-reviewed and published.
FBC:SM
http://www.micropublication.org
A version of a scientific manuscript that is shared publicly on the web without peer review. In most cases, work posted as a preprint will be submitted for peer review at a journal.
http://orcid.org/0000-0002-1373-1705
2019-06-25T09:00:50Z
pub_type
FBcv:0007001
preprint
A version of a scientific manuscript that is shared publicly on the web without peer review. In most cases, work posted as a preprint will be submitted for peer review at a journal.
FBC:SM
http://www.asapbio.org/preprint-info
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to regulate the activity of a neuron. This is often achieved by manipulation of membrane potential or synaptic transmission dynamics.
http://orcid.org/0000-0002-1373-1705
2019-06-25T09:54:56Z
electrically signalling cell activity regulation tool
experimental_tool_descriptor
FBcv:0007002
neuron activity regulation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to regulate the activity of a neuron. This is often achieved by manipulation of membrane potential or synaptic transmission dynamics.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron. This is often achieved by inducing membrane hyperpolarization (GO:0060081).
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:13:24Z
electrically signalling cell inhibition tool
experimental_tool_descriptor
FBcv:0007003
neuron inhibition tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron. This is often achieved by inducing membrane hyperpolarization (GO:0060081).
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated in response to a particular stimulus.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:15:49Z
experimental_tool_descriptor
FBcv:0007004
conditional neuron inhibition tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated in response to a particular stimulus.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by irradiation with a pulse of light.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:17:16Z
optogenetic neuron inhibition tool
experimental_tool_descriptor
FBcv:0007005
light-regulated neuron inhibition tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by irradiation with a pulse of light.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:18:34Z
experimental_tool_descriptor
FBcv:0007006
small molecule-regulated neuron inhibition tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by temperature.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:20:00Z
thermogenetic neuron inhibition tool
experimental_tool_descriptor
FBcv:0007007
temperature-regulated neuron inhibition tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to inhibit the activity of a neuron, where this property can be regulated by temperature.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron. This is often achieved by inducing membrane depolarization (GO:0051899).
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:25:57Z
electrically signalling cell activation tool
experimental_tool_descriptor
FBcv:0007008
neuron activation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron. This is often achieved by inducing membrane depolarization (GO:0051899).
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated in response to a particular stimulus.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:26:57Z
experimental_tool_descriptor
FBcv:0007009
conditional neuron activation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated in response to a particular stimulus.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by temperature.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:28:57Z
thermogenetic neuron activation tool
experimental_tool_descriptor
FBcv:0007010
temperature-regulated neuron activation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by temperature.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by irradiation with a pulse of light.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:31:02Z
optogenetic neuron activation tool
experimental_tool_descriptor
FBcv:0007011
light-regulated neuron activation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by irradiation with a pulse of light.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:34:48Z
experimental_tool_descriptor
FBcv:0007012
small molecule-regulated neuron activation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to stimulate the activity of a neuron, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:53:21Z
experimental_tool_descriptor
FBcv:0007013
cell ablation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated in response to a particular stimulus.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:54:32Z
experimental_tool_descriptor
FBcv:0007014
conditional cell ablation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated in response to a particular stimulus.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by temperature.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:55:40Z
experimental_tool_descriptor
FBcv:0007015
temperature-regulated cell ablation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by temperature.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by irradiation with a pulse of light.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:56:47Z
experimental_tool_descriptor
FBcv:0007016
light-regulated cell ablation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by irradiation with a pulse of light.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
http://orcid.org/0000-0002-1373-1705
2019-06-25T10:57:45Z
experimental_tool_descriptor
FBcv:0007017
small molecule-regulated cell ablation tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property used to ablate a specific cell or anatomical structure, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activity of a specific biological process.
http://orcid.org/0000-0002-1373-1705
2019-06-25T11:38:48Z
reporter of biological process pathway activity
experimental_tool_descriptor
FBcv:0007018
biological process activity sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activity of a specific biological process.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activity of a specific signal transduction pathway.
http://orcid.org/0000-0002-1373-1705
2019-06-25T11:41:19Z
reporter of signal transduction pathway activity
experimental_tool_descriptor
FBcv:0007019
signal transduction pathway activity sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activity of a specific signal transduction pathway.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activation state of a specific gene product.
http://orcid.org/0000-0002-1373-1705
2019-06-25T11:43:24Z
gene product activation state detection tool
experimental_tool_descriptor
FBcv:0007020
gene product activity sensor
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that is used to provide a readout of the activation state of a specific gene product.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring macromolecules, facilitating the subsequent purification or detection of the tagged macromolecules by an experimental method.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:01:14Z
experimental_tool_descriptor
FBcv:0007021
proximity labeling tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring macromolecules, facilitating the subsequent purification or detection of the tagged macromolecules by an experimental method.
FBC:GM
PMID:30774936
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring proteins, facilitating the subsequent purification or detection of the tagged proteins by an experimental method.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:08:26Z
experimental_tool_descriptor
FBcv:0007022
proximity labeling tool (protein)
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring proteins, facilitating the subsequent purification or detection of the tagged proteins by an experimental method.
FBC:GM
PMID:29125959
PMID:30774936
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring RNA, facilitating the subsequent purification or detection of the tagged RNA by an experimental method.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:18:36Z
experimental_tool_descriptor
FBcv:0007023
proximity labeling tool (RNA)
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring RNA, facilitating the subsequent purification or detection of the tagged RNA by an experimental method.
FBC:GM
PMID:30774936
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring DNA, facilitating the subsequent purification or detection of the tagged DNA by an experimental method.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:24:50Z
experimental_tool_descriptor
FBcv:0007024
proximity labeling tool (DNA)
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that encodes an enzyme which covalently tags neighboring DNA, facilitating the subsequent purification or detection of the tagged DNA by an experimental method.
FBC:GM
PMID:30774936
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to facilitate the detection of a specific cell population by an experimental method.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:41:38Z
experimental_tool_descriptor
FBcv:0007025
cell labeling tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and that confers a specific property that can be used to facilitate the detection of a specific cell population by an experimental method.
FBC:GM
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific property that can be used to stochastically label cells in the same sample with different colors of fluorescent protein. This property can be exploited to study cell morphology and to track lineages of clonally related cells.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:42:41Z
experimental_tool_descriptor
FBcv:0007026
multicolor cell labeling tool
Sequence that forms all or part of the gene product encoded by a transgenic locus or modified endogenous locus and confers a specific property that can be used to stochastically label cells in the same sample with different colors of fluorescent protein. This property can be exploited to study cell morphology and to track lineages of clonally related cells.
FBC:GM
PMID:25491327
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which allows the tagged protein product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process that can be regulated by binding to a small molecule, such as an ion or ligand.
http://orcid.org/0000-0002-1373-1705
2019-06-25T14:58:18Z
experimental_tool_descriptor
FBcv:0007027
small molecule-regulated protein cleavage tag
Sequence that forms part of the protein product encoded by a transgenic locus or modified endogenous locus and which allows the tagged protein product to be cleaved (broken into smaller molecules by the rupture of a covalent bond) by a specific process that can be regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
Catalytically inactive fragment of a recombinase. A functional recombinase can be reconstituted when complementary split recombinase fragments are brought together in vivo by fusing the fragments to peptides that physically interact.
http://orcid.org/0000-0002-1373-1705
2019-06-26T07:55:34Z
experimental_tool_descriptor
FBcv:0007028
split recombinase
Catalytically inactive fragment of a recombinase. A functional recombinase can be reconstituted when complementary split recombinase fragments are brought together in vivo by fusing the fragments to peptides that physically interact.
FBC:GM
Sequence that has a property that allows specific binding to another macromolecule.
http://orcid.org/0000-0002-1373-1705
2019-06-26T08:11:17Z
experimental_tool_descriptor
FBcv:0007029
specific binding tool
Sequence that has a property that allows specific binding to another macromolecule.
FBC:GM
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated in response to a particular stimulus.
http://orcid.org/0000-0002-1373-1705
2019-06-26T08:12:05Z
experimental_tool_descriptor
FBcv:0007030
conditional specific binding tool
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated in response to a particular stimulus.
FBC:GM
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by irradiation with a pulse of light.
http://orcid.org/0000-0002-1373-1705
2019-06-26T08:13:06Z
experimental_tool_descriptor
FBcv:0007031
light-regulated specific binding tool
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by irradiation with a pulse of light.
FBC:GM
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by temperature.
http://orcid.org/0000-0002-1373-1705
2019-06-26T08:13:56Z
experimental_tool_descriptor
FBcv:0007032
temperature-regulated specific binding tool
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by temperature.
FBC:GM
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
http://orcid.org/0000-0002-1373-1705
2019-06-26T08:14:35Z
experimental_tool_descriptor
FBcv:0007033
small molecule-regulated specific binding tool
Sequence that has a property that allows specific binding to another macromolecule, where this property can be regulated by binding to a small molecule, such as an ion or ligand.
FBC:GM
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner, having a cognate recognition site of 20-30bp. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
http://orcid.org/0000-0002-1373-1705
2019-06-26T09:17:20Z
experimental_tool_descriptor
FBcv:0007035
meganuclease
An enzyme that catalyzes hydrolysis of DNA in a site-specific manner, having a cognate recognition site of 20-30bp. When used in vivo, the DNA cutting stimulates cellular repair mechanisms, which can be exploited to produce genome modifications. For example, repair by homologous recombination in the presence of an exogenous template can be used to introduce targeted changes into the genome.
FBC:GM
FlyBase:FBrf0231034
Work consisting of speeches read or delivered before an audience or class, especially for instruction or to set forth some subject.
http://orcid.org/0000-0002-1373-1705
2020-01-23T15:24:54Z
pub_type
FBcv:0007036
lecture
Work consisting of speeches read or delivered before an audience or class, especially for instruction or to set forth some subject.
MeSH:D019531
An immunoglobulin molecule having a specific amino acid sequence that gives each antibody the ability to adhere to and interact with the antigen that induced its synthesis and with molecules containing structures similar to that antigen. An antigen is any substance capable of inducing a specific immune response, including but not limited to toxins, bacterial proteins and viruses.
http://orcid.org/0000-0002-1373-1705
2020-01-24T08:44:55Z
XCO:0000194
experimental_tool_descriptor
FBcv:0007037
antibody
An immunoglobulin molecule having a specific amino acid sequence that gives each antibody the ability to adhere to and interact with the antigen that induced its synthesis and with molecules containing structures similar to that antigen. An antigen is any substance capable of inducing a specific immune response, including but not limited to toxins, bacterial proteins and viruses.
XCO:0000194
Phenotype expressed only in the presence or absence of light, which may be white light or particular wavelength(s).
http://orcid.org/0000-0002-1373-1705
2020-01-24T09:10:41Z
environmental_qualifier
FBcv:0007038
light conditional
Phenotype expressed only in the presence or absence of light, which may be white light or particular wavelength(s).
FBC:CP
An antibody whose domain architecture has been engineered in vitro. An engineered antibody typically contains only a subset of the domains found in a naturally occurring antibody. In some cases, domains that are normally found in different chains of a naturally occurring antibody are synthesized as a single fusion protein.
http://orcid.org/0000-0002-1373-1705
2020-02-03T11:36:12Z
experimental_tool_descriptor
FBcv:0007039
engineered antibody
An antibody whose domain architecture has been engineered in vitro. An engineered antibody typically contains only a subset of the domains found in a naturally occurring antibody. In some cases, domains that are normally found in different chains of a naturally occurring antibody are synthesized as a single fusion protein.
FBC:GM
An engineered antibody consisting of the antigen-binding variable domain (VHH domain) of a camelid single-domain heavy chain antibody (HCab).
http://orcid.org/0000-0002-1373-1705
2020-02-03T11:51:11Z
experimental_tool_descriptor
FBcv:0007040
nanobody
An engineered antibody consisting of the antigen-binding variable domain (VHH domain) of a camelid single-domain heavy chain antibody (HCab).
FBC:GM
PMID:22886243
PMID:8502296
PMID:9323027
An engineered antibody consisting of the heavy (VH) and light (VL) chains of an immunoglobulin, separated by a short flexible linker peptide and expressed as a single fusion protein.
http://orcid.org/0000-0002-1373-1705
2020-02-03T12:25:24Z
sFv antibody
scFv antibody
single-chain variable region fragment antibody
experimental_tool_descriptor
FBcv:0007041
single-chain variable fragment antibody
An engineered antibody consisting of the heavy (VH) and light (VL) chains of an immunoglobulin, separated by a short flexible linker peptide and expressed as a single fusion protein.
FBC:GM
PMID:3045807
sFv antibody
PMID:3045807
scFv antibody
FBC:GM
single-chain variable region fragment antibody
PMID:3045807
An RMCE target element contains a region of DNA sequence flanked by a pair of target sites for a recombinase or an integrase, which are arranged such that this target sequence cassette can be replaced with donor sequence from a compatible RMCE donor element via recombination-mediated cassette exchange (RMCE). For RMCE mediated by a recombinase, the target cassette is flanked by two non-identical recombinase target sites that each carry a different mutation in the spacer sequence of the target site; this renders the two sites incompatible with each other. A compatible RMCE donor cassette is flanked by the same pair of non-identical sites; in the presence of recombinase, a double recombination event between the identical sites on the donor and target sequences results in replacement of the target cassette with the donor cassette. In the case of RMCE mediated by an integrase, the RMCE cassette is flanked by identical integrase target sites, while a compatible RMCE donor cassette is flanked by copies of the orthogonal integrase target site; in the presence of integrase, a double recombination event results in the target cassette being replaced with that of the donor cassette. In this case, if the flanking sites are in inverted orientation, replacement of the target cassette can occur in either direction.
http://orcid.org/0000-0002-1373-1705
2020-02-03T14:52:50Z
recombination-mediated cassette exchange target element
experimental_tool_descriptor
FBcv:0007042
RMCE target element
An RMCE target element contains a region of DNA sequence flanked by a pair of target sites for a recombinase or an integrase, which are arranged such that this target sequence cassette can be replaced with donor sequence from a compatible RMCE donor element via recombination-mediated cassette exchange (RMCE). For RMCE mediated by a recombinase, the target cassette is flanked by two non-identical recombinase target sites that each carry a different mutation in the spacer sequence of the target site; this renders the two sites incompatible with each other. A compatible RMCE donor cassette is flanked by the same pair of non-identical sites; in the presence of recombinase, a double recombination event between the identical sites on the donor and target sequences results in replacement of the target cassette with the donor cassette. In the case of RMCE mediated by an integrase, the RMCE cassette is flanked by identical integrase target sites, while a compatible RMCE donor cassette is flanked by copies of the orthogonal integrase target site; in the presence of integrase, a double recombination event results in the target cassette being replaced with that of the donor cassette. In this case, if the flanking sites are in inverted orientation, replacement of the target cassette can occur in either direction.
FBC:GM
FlyBase:FBrf0231034
PMID:21445009
PMID:7947678
An RMCE donor element contains a region of DNA sequence flanked by a pair of target sites for a recombinase or an integrase, which are arranged such that this donor sequence cassette can be used to replace target sequence of a compatible RMCE target element via recombination-mediated cassette exchange (RMCE). For RMCE mediated by a recombinase, the target cassette is flanked by two non-identical recombinase target sites that each carry a different mutation in the spacer sequence of the target site; this renders the two sites incompatible with each other. A compatible RMCE donor cassette is flanked by the same pair of non-identical sites; in the presence of recombinase, a double recombination event between the identical sites on the donor and target sequences results in replacement of the target cassette with the donor cassette. In the case of RMCE mediated by an integrase, the RMCE cassette is flanked by identical integrase target sites, while a compatible RMCE donor cassette is flanked by copies of the orthogonal integrase target site; in the presence of integrase, a double recombination event results in the target cassette being replaced with that of the donor cassette. In this case, if the flanking sites are in inverted orientation, replacement of the target cassette can occur in either direction.
http://orcid.org/0000-0002-1373-1705
2020-02-03T15:00:41Z
recombination-mediated cassette exchange donor element
experimental_tool_descriptor
FBcv:0007043
RMCE donor element
An RMCE donor element contains a region of DNA sequence flanked by a pair of target sites for a recombinase or an integrase, which are arranged such that this donor sequence cassette can be used to replace target sequence of a compatible RMCE target element via recombination-mediated cassette exchange (RMCE). For RMCE mediated by a recombinase, the target cassette is flanked by two non-identical recombinase target sites that each carry a different mutation in the spacer sequence of the target site; this renders the two sites incompatible with each other. A compatible RMCE donor cassette is flanked by the same pair of non-identical sites; in the presence of recombinase, a double recombination event between the identical sites on the donor and target sequences results in replacement of the target cassette with the donor cassette. In the case of RMCE mediated by an integrase, the RMCE cassette is flanked by identical integrase target sites, while a compatible RMCE donor cassette is flanked by copies of the orthogonal integrase target site; in the presence of integrase, a double recombination event results in the target cassette being replaced with that of the donor cassette. In this case, if the flanking sites are in inverted orientation, replacement of the target cassette can occur in either direction.
FBC:GM
FlyBase:FBrf0231034
PMID:21445009
PMID:7947678
A docking element is an element that has been introduced into a site in the genome to allow integration of DNA at a defined location; this neutralizes the problem of position effects that are seen with non-specific insertion techniques such as transposable-element-mediated transgenesis. A docking element contains a single target site for an integrase, allowing subsequent integration of DNA into this site from a donor element via integrase mediated recombination. The docking element in the genome typically contains the 'attB' site and the donor plasmid contains the 'attP' site, since this directionality gives higher integration rates compared to the alternative combination where the 'attB' site is integrated into the genome. A docking element insertion is typically selected to be 'benign' (that is it does not result in disruption of an endogenous locus) and to show a high rate of integration in the presence of integrase.
http://orcid.org/0000-0002-1373-1705
2020-02-03T15:54:09Z
docking site element
landing site element
experimental_tool_descriptor
FBcv:0007044
This includes any element containing a single site for integrase-mediated integration, as in FBrf0231034 Fig 10a, but not elements with multiple integrase sites, as in FBrf0231034 Fig 10b (see FBcv:0007042 - RMCE target element). Elements with sites for recombinase-mediated exchange (as in FBrf0231034 Fig 10c) are only included if they additionally carry exactly one integrase site for integrase-mediated integration.
docking element
A docking element is an element that has been introduced into a site in the genome to allow integration of DNA at a defined location; this neutralizes the problem of position effects that are seen with non-specific insertion techniques such as transposable-element-mediated transgenesis. A docking element contains a single target site for an integrase, allowing subsequent integration of DNA into this site from a donor element via integrase mediated recombination. The docking element in the genome typically contains the 'attB' site and the donor plasmid contains the 'attP' site, since this directionality gives higher integration rates compared to the alternative combination where the 'attB' site is integrated into the genome. A docking element insertion is typically selected to be 'benign' (that is it does not result in disruption of an endogenous locus) and to show a high rate of integration in the presence of integrase.
FBC:GM
FlyBase:FBrf0192974
FlyBase:FBrf0194996
FlyBase:FBrf0231034
PMID:11359900
PMID:12563279
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which can be used to modify an RNA of interest in a defined manner. Examples of RNA engineering include the targeting of an individual transcript for knockdown, and targeted manipulation of RNA splicing or editing.
http://orcid.org/0000-0002-1373-1705
2020-02-04T09:01:14Z
experimental_tool_descriptor
FBcv:0007045
RNA engineering tool
Sequence that forms all or part of a transgenic locus or modified endogenous locus and which can be used to modify an RNA of interest in a defined manner. Examples of RNA engineering include the targeting of an individual transcript for knockdown, and targeted manipulation of RNA splicing or editing.
FBC:GM
PMID:30021724
PMID:30388409
PMID:31367845
An enzyme that catalyzes hydrolysis of RNA in a site-specific manner, and in which the specificity is determined by a guide RNA that contains sequence complementary to the target RNA sequence of interest, rather than being an inherent property of the ribonuclease itself. This property can be used to modify an organism's transcriptome in a defined manner.
http://orcid.org/0000-0002-1373-1705
2020-02-04T09:12:14Z
experimental_tool_descriptor
FBcv:0007046
RNA-guided ribonuclease
An enzyme that catalyzes hydrolysis of RNA in a site-specific manner, and in which the specificity is determined by a guide RNA that contains sequence complementary to the target RNA sequence of interest, rather than being an inherent property of the ribonuclease itself. This property can be used to modify an organism's transcriptome in a defined manner.
FBC:GM
PMID:30021724
PMID:30388409
PMID:31367845
FlyBase miscellaneous CV
FBcv:0010000
Consider - FBsv:0000002.
living stock
true
FlyBase miscellaneous CV
FBcv:0010001
Consider - FBsv:0000003.
molecular extract
true
FlyBase miscellaneous CV
FBcv:0010002
Consider - FBsv:0000005.
preserved specimen
true
FlyBase miscellaneous CV
FBcv:0010003
E cytotype stock
true
FlyBase miscellaneous CV
FBcv:0010004
M cytotype stock
true
FlyBase miscellaneous CV
FBcv:0010005
Consider - FBsv:0000004.
genomic DNA
true
FlyBase miscellaneous CV
FBcv:0010006
Consider - FBsv:0000007.
ethanol-preserved specimen
true
FlyBase miscellaneous CV
FBcv:0010007
pinned specimen
true
FlyBase miscellaneous CV
FBcv:0010009
Consider - FBsv:0001010.
fluorescent balancer
true
FlyBase miscellaneous CV
FBcv:0010010
Consider - FBsv:0001011.
lacZ balancer
true
FlyBase miscellaneous CV
FBcv:0010011
laboratory wild-type stock
true
FlyBase miscellaneous CV
FBcv:0010012
Consider - FBsv:0000100.
collection
true
FlyBase miscellaneous CV
FBcv:0010013
Consider - FBsv:0000101.
stock center collection
true
FlyBase miscellaneous CV
FBcv:0010014
Consider - FBsv:0000102.
laboratory collection
true
FlyBase miscellaneous CV
FBcv:0010015
Saxton laboratory
true
FlyBase miscellaneous CV
FBcv:0010016
Consider - FBsv:0000109.
Garcia-Bellido laboratory
true
FlyBase miscellaneous CV
FBcv:0010017
Consider - FBsv:0000108.
Nusslein-Volhard laboratory
true
FlyBase miscellaneous CV
FBcv:0010018
Consider - FBsv:0000110.
Carpenter laboratory
true
FlyBase miscellaneous CV
Harvard Medical School Exelixis Drosophila Collection
FBcv:0010019
Artavanis laboratory
true
FlyBase miscellaneous CV
Artavanis-Tsakonas laboratory
FBcv:0010020
Consider - FBsv:0000105.
Exelixis Drosophila Stock Collection at Harvard Medical School
true
Bloomington
FlyBase miscellaneous CV
BDSC
BSC
FBcv:0010021
Consider - FBsv:0000103.
Bloomington Drosophila Stock Center
true
species stock center
FlyBase miscellaneous CV
Drosophila species stock center
Tucson
FBcv:0010022
Consider - FBsv:0000106.
San Diego Drosophila Species Stock Center
true
FlyBase miscellaneous CV
Szeged
FBcv:0010023
Szeged Drosophila Stock Centre
true
FlyBase miscellaneous CV
DGRC
Kyoto
Kyoto stock center
FBcv:0010024
Consider - FBsv:0000104.
Drosophila Genetic Resource Center
true
molecular process
molecular_function
catalytic activity
biological_process
true
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Any entity that is ordered in discrete units along a linear axis.
Chris Mungall
sequentially ordered entity
Any individual unit of a collection of like units arranged in a linear order
Chris Mungall
An individual unit can be a molecular entity such as a base pair, or an abstract entity, such as the abstraction of a base pair.
sequence atomic unit
A material entity consisting of multiple components that are causally integrated.
May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43
Chris Mungall
http://www.jbiomedsem.com/content/4/1/43
system
ready for release
pending final vetting
requires discussion
## Elucidation
This is used when the statement/axiom is assumed to hold true 'eternally'
## How to interpret (informal)
First the "atemporal" FOL is derived from the OWL using the standard
interpretation. This axiom is temporalized by embedding the axiom
within a for-all-times quantified sentence. The t argument is added to
all instantiation predicates and predicates that use this relation.
## Example
Class: nucleus
SubClassOf: part_of some cell
forall t :
forall n :
instance_of(n,Nucleus,t)
implies
exists c :
instance_of(c,Cell,t)
part_of(n,c,t)
## Notes
This interpretation is *not* the same as an at-all-times relation
axiom holds for all times
true
MF(X)-directly_regulates->MF(Y)-enabled_by->GP(Z) => MF(Y)-has_input->GP(Y) e.g. if 'protein kinase activity'(X) directly_regulates 'protein binding activity (Y)and this is enabled by GP(Z) then X has_input Z
infer input from direct reg
GP(X)-enables->MF(Y)-has_part->MF(Z) => GP(X) enables MF(Z),
e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase coupled transporter activity' has_part 'ATPase activity' then GP(X) enables 'ATPase activity'
enabling an MF enables its parts
true
GP(X)-enables->MF(Y)-part_of->BP(Z) => GP(X) involved_in BP(Z) e.g. if X enables 'protein kinase activity' and Y 'part of' 'signal tranduction' then X involved in 'signal transduction'
involved in BP
This rule is dubious: added as a quick fix for expected inference in GO-CAM. The problem is most acute for transmembrane proteins, such as receptors or cell adhesion molecules, which have some subfunctions inside the cell (e.g. kinase activity) and some subfunctions outside (e.g. ligand binding). Correct annotation of where these functions occurs leads to incorrect inference about the location of the whole protein. This should probably be weakened to "... -> overlaps"
If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this.
inferring direct reg edge from input to regulatory subfunction
inferring direct neg reg edge from input to regulatory subfunction
inferring direct positive reg edge from input to regulatory subfunction
effector input is compound function input
Input of effector is input of its parent MF
if effector directly regulates X, its parent MF directly regulates X
if effector directly positively regulates X, its parent MF directly positively regulates X
if effector directly negatively regulates X, its parent MF directly negatively regulates X
'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).
'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).